François Paquet-Durand - Publications

Affiliations: 
Institute for Ophthalmic Research University of Tuebingen, Germany, Tübingen, Baden-Württemberg, Germany 

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Samardzija M, Corna A, Gomez-Sintes R, Jarboui MA, Armento A, Roger JE, Petridou E, Haq W, Paquet-Durand F, Zrenner E, de la Villa P, Zeck G, Grimm C, Boya P, Ueffing M, et al. HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice. Cell Death and Differentiation. PMID 33159184 DOI: 10.1038/s41418-020-00653-3  0.48
2020 Fischer MD, Michalakis S, Wilhelm B, Zobor D, Muehlfriedel R, Kohl S, Weisschuh N, Ochakovski GA, Klein R, Schoen C, Sothilingam V, Garcia-Garrido M, Kuehlewein L, Kahle N, Werner A, ... ... Paquet-Durand F, et al. Safety and Vision Outcomes of Subretinal Gene Therapy Targeting Cone Photoreceptors in Achromatopsia: A Nonrandomized Controlled Trial. Jama Ophthalmology. PMID 32352493 DOI: 10.1001/jamaophthalmol.2020.1032  0.48
2019 Paquet-Durand F, Marigo V, Ekström P. RD Genes Associated with High Photoreceptor cGMP-Levels (Mini-Review). Advances in Experimental Medicine and Biology. 1185: 245-249. PMID 31884619 DOI: 10.1007/978-3-030-27378-1_40  0.36
2019 Power M, Das S, Schütze K, Marigo V, Ekström P, Paquet-Durand F. Cellular mechanisms of hereditary photoreceptor degeneration - Focus on cGMP. Progress in Retinal and Eye Research. PMID 31374251 DOI: 10.1016/j.preteyeres.2019.07.005  0.36
2019 Himawan E, Ekström P, Buzgo M, Gaillard P, Stefánsson E, Marigo V, Loftsson T, Paquet-Durand F. Drug delivery to retinal photoreceptors. Drug Discovery Today. PMID 30877076 DOI: 10.1016/j.drudis.2019.03.004  0.36
2018 Mencl S, Trifunović D, Zrenner E, Paquet-Durand F. PKG-Dependent Cell Death in 661W Cone Photoreceptor-like Cell Cultures (Experimental Study). Advances in Experimental Medicine and Biology. 1074: 511-517. PMID 29721983 DOI: 10.1007/978-3-319-75402-4_63  0.48
2018 Trifunović D, Petridou E, Comitato A, Marigo V, Ueffing M, Paquet-Durand F. Primary Rod and Cone Degeneration Is Prevented by HDAC Inhibition. Advances in Experimental Medicine and Biology. 1074: 367-373. PMID 29721965 DOI: 10.1007/978-3-319-75402-4_45  0.48
2018 Vighi E, Trifunović D, Veiga-Crespo P, Rentsch A, Hoffmann D, Sahaboglu A, Strasser T, Kulkarni M, Bertolotti E, van den Heuvel A, Peters T, Reijerkerk A, Euler T, Ueffing M, Schwede F, ... ... Paquet-Durand F, et al. Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 29531030 DOI: 10.1073/pnas.1718792115  0.48
2017 Schön C, Sothilingam V, Mühlfriedel R, Garcia Garrido M, Beck SC, Tanimoto N, Wissinger B, Paquet-Durand F, Biel M, Michalakis S, Seeliger MW, Consortium RC. Gene therapy successfully delays degeneration in a mouse model of PDE6A-linked retinitis pigmentosa (RP 43). Human Gene Therapy. PMID 29212391 DOI: 10.1089/hum.2017.156  0.4
2017 Sahaboglu A, Sharif A, Feng L, Secer E, Zrenner E, Paquet-Durand F. Temporal progression of PARP activity in the Prph2 mutant rd2 mouse: Neuroprotective effects of the PARP inhibitor PJ34. Plos One. 12: e0181374. PMID 28723922 DOI: 10.1371/journal.pone.0181374  0.48
2016 Trifunović D, Arango-Gonzalez B, Comitato A, Barth M, Del Amo EM, Kulkarni M, Sahaboglu A, Hauck SM, Urtti A, Arsenijevic Y, Ueffing M, Marigo V, Paquet-Durand F. HDAC inhibition in the cpfl1 mouse protects degenerating cone photoreceptors in vivo. Human Molecular Genetics. 25: 4462-4472. PMID 28172811 DOI: 10.1093/hmg/ddw275  0.48
2016 Sahaboglu A, Barth M, Secer E, Amo EM, Urtti A, Arsenijevic Y, Zrenner E, Paquet-Durand F. Olaparib significantly delays photoreceptor loss in a model for hereditary retinal degeneration. Scientific Reports. 6: 39537. PMID 28004814 DOI: 10.1038/srep39537  0.48
2016 Trifunović D, Arango-Gonzalez B, Comitato A, Barth M, Del Amo EM, Kulkarni M, Sahaboglu A, Hauck SM, Urtti A, Arsenijevic Y, Ueffing M, Marigo V, Paquet-Durand F. HDAC inhibition in the cpfl1 mouse protects degenerating cone photoreceptors in vivo. Human Molecular Genetics. PMID 27530254 DOI: 10.1093/hmg/ddw275  0.48
2016 Kulkarni M, Trifunović D, Schubert T, Euler T, Paquet-Durand F. Calcium dynamics change in degenerating cone photoreceptors. Human Molecular Genetics. PMID 27402880 DOI: 10.1093/hmg/ddw219  0.44
2016 Schön C, Paquet-Durand F, Michalakis S. Cav1.4 L-Type Calcium Channels Contribute to Calpain Activation in Degenerating Photoreceptors of rd1 Mice. Plos One. 11: e0156974. PMID 27270916 DOI: 10.1371/journal.pone.0156974  0.48
2016 Valdés J, Trachsel-Moncho L, Sahaboglu A, Trifunović D, Miranda M, Ueffing M, Paquet-Durand F, Schmachtenberg O. Organotypic retinal explant cultures as in vitro alternative for diabetic retinopathy studies. Altex. PMID 27159027 DOI: 10.14573/altex.1603111  0.48
2015 Trifunović D, Djedović N, Lavrnja I, Wendrich KS, Paquet-Durand F, Miljković D. Cell death of spinal cord ED1(+) cells in a rat model of multiple sclerosis. Peerj. 3: e1189. PMID 26413432 DOI: 10.7717/peerj.1189  0.48
2015 Sothilingam V, Garcia Garrido M, Jiao K, Buena-Atienza E, Sahaboglu A, Trifunović D, Balendran S, Koepfli T, Mühlfriedel R, Schön C, Biel M, Heckmann A, Beck SC, Michalakis S, Wissinger B, ... ... Paquet-Durand F, et al. Retinitis pigmentosa: impact of different Pde6a point mutations on the disease phenotype. Human Molecular Genetics. PMID 26188004 DOI: 10.1093/hmg/ddv275  0.48
2015 Kulkarni M, Schubert T, Baden T, Wissinger B, Euler T, Paquet-Durand F. Imaging Ca2+ dynamics in cone photoreceptor axon terminals of the mouse retina. Journal of Visualized Experiments : Jove. e52588. PMID 25993489 DOI: 10.3791/52588  0.4
2015 Schubert T, Gleiser C, Heiduschka P, Franz C, Nagel-Wolfrum K, Sahaboglu A, Weisschuh N, Eske G, Rohbock K, Rieger N, Paquet-Durand F, Wissinger B, Wolfrum U, Hirt B, Singer W, et al. Deletion of myosin VI causes slow retinal optic neuropathy and age-related macular degeneration (AMD)-relevant retinal phenotype. Cellular and Molecular Life Sciences : Cmls. 72: 3953-69. PMID 25939269 DOI: 10.1007/s00018-015-1913-3  0.44
2015 Brennenstuhl C, Tanimoto N, Burkard M, Wagner R, Bolz S, Trifunovic D, Kabagema-Bilan C, Paquet-Durand F, Beck SC, Huber G, Seeliger MW, Ruth P, Wissinger B, Lukowski R. Targeted ablation of the Pde6h gene in mice reveals cross-species differences in cone and rod phototransduction protein isoform inventory. The Journal of Biological Chemistry. 290: 10242-55. PMID 25739440 DOI: 10.1074/jbc.M114.611921  0.48
2015 Kulkarni M, Schubert T, Baden T, Wissinger B, Euler T, Paquet-Durand F. Imaging Ca2+ dynamics in cone photoreceptor axon terminals of the mouse retina Journal of Visualized Experiments. 2015. DOI: 10.3791/52588  0.48
2015 Schubert T, Gleiser C, Heiduschka P, Franz C, Nagel-Wolfrum K, Sahaboglu A, Weisschuh N, Eske G, Rohbock K, Rieger N, Paquet-Durand F, Wissinger B, Wolfrum U, Hirt B, Singer W, et al. Deletion of myosin VI causes slow retinal optic neuropathy and age-related macular degeneration (AMD)-relevant retinal phenotype Cellular and Molecular Life Sciences. DOI: 10.1007/s00018-015-1913-3  0.48
2014 Farinelli P, Perera A, Arango-Gonzalez B, Trifunovic D, Wagner M, Carell T, Biel M, Zrenner E, Michalakis S, Paquet-Durand F, Ekström PA. DNA methylation and differential gene regulation in photoreceptor cell death. Cell Death & Disease. 5: e1558. PMID 25476906 DOI: 10.1038/cddis.2014.512  0.48
2014 Arango-Gonzalez B, Trifunović D, Sahaboglu A, Kranz K, Michalakis S, Farinelli P, Koch S, Koch F, Cottet S, Janssen-Bienhold U, Dedek K, Biel M, Zrenner E, Euler T, Ekström P, ... ... Paquet-Durand F, et al. Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration. Plos One. 9: e112142. PMID 25392995 DOI: 10.1371/journal.pone.0112142  0.48
2014 Carido M, Zhu Y, Postel K, Benkner B, Cimalla P, Karl MO, Kurth T, Paquet-Durand F, Koch E, Münch TA, Tanaka EM, Ader M. Characterization of a mouse model with complete RPE loss and its use for RPE cell transplantation. Investigative Ophthalmology & Visual Science. 55: 5431-44. PMID 25103259 DOI: 10.1167/iovs.14-14325  0.48
2014 Ekström PA, Ueffing M, Zrenner E, Paquet-Durand F. Novel in situ activity assays for the quantitative molecular analysis of neurodegenerative processes in the retina. Current Medicinal Chemistry. 21: 3478-93. PMID 24934347  0.48
2014 Sahaboglu A, Tanimoto N, Bolz S, Garrido MG, Ueffing M, Seeliger MW, Löwenheim H, Ekström P, Paquet-Durand F. Knockout of PARG110 confers resistance to cGMP-induced toxicity in mammalian photoreceptors. Cell Death & Disease. 5: e1234. PMID 24853412 DOI: 10.1038/cddis.2014.208  0.48
2014 Paquet-Durand F, Sahaboglu A, Dietter J, Paquet-Durand O, Hitzmann B, Ueffing M, Ekström PAR. How long does a photoreceptor cell take to die? Implications for the causative cell death mechanisms Advances in Experimental Medicine and Biology. 801: 575-581. PMID 24664746 DOI: 10.1007/978-1-4614-3209-8_73  0.48
2014 Sahaboglu A, Bolz S, Löwenheim H, Paquet-Durand F. Expression of poly(ADP-ribose) glycohydrolase in wild-type and PARG-110 knock-out retina. Advances in Experimental Medicine and Biology. 801: 463-9. PMID 24664732 DOI: 10.1007/978-1-4614-3209-8_59  0.48
2014 Arango-Gonzalez B, Leitritz MA, Fischer D, Gerberding M, Paquet-Durand F, Ueffing M. [Current therapeutic approaches in inherited retinal degeneration: from genes to chip]. Klinische MonatsbläTter FüR Augenheilkunde. 231: 222-31. PMID 24658859 DOI: 10.1055/s-0033-1360259  0.48
2013 Du J, Cleghorn WM, Contreras L, Lindsay K, Rountree AM, Chertov AO, Turner SJ, Sahaboglu A, Linton J, Sadilek M, Satrústegui J, Sweet IR, Paquet-Durand F, Hurley JB. Inhibition of mitochondrial pyruvate transport by zaprinast causes massive accumulation of aspartate at the expense of glutamate in the retina. The Journal of Biological Chemistry. 288: 36129-40. PMID 24187136 DOI: 10.1074/jbc.M113.507285  0.44
2013 Farinelli P, Arango-Gonzalez B, Völkl J, Alesutan I, Lang F, Zrenner E, Paquet-Durand F, Ekström PA. Retinitis Pigmentosa: over-expression of anti-ageing protein Klotho in degenerating photoreceptors. Journal of Neurochemistry. 127: 868-79. PMID 23796581 DOI: 10.1111/jnc.12353  0.48
2013 Kranz K, Paquet-Durand F, Weiler R, Janssen-Bienhold U, Dedek K. Testing for a gap junction-mediated bystander effect in retinitis pigmentosa: secondary cone death is not altered by deletion of connexin36 from cones. Plos One. 8: e57163. PMID 23468924 DOI: 10.1371/journal.pone.0057163  0.48
2013 Sahaboglu A, Paquet-Durand O, Dietter J, Dengler K, Bernhard-Kurz S, Ekström PAR, Hitzmann B, Ueffing M, Paquet-Durand F. Retinitis pigmentosa: Rapid neurodegeneration is governed by slow cell death mechanisms Cell Death and Disease. 4. PMID 23392176 DOI: 10.1038/cddis.2013.12  0.48
2013 Hübener J, Weber JJ, Richter C, Honold L, Weiss A, Murad F, Breuer P, Wüllner U, Bellstedt P, Paquet-Durand F, Takano J, Saido TC, Riess O, Nguyen HP. Calpain-mediated ataxin-3 cleavage in the molecular pathogenesis of spinocerebellar ataxia type 3 (SCA3). Human Molecular Genetics. 22: 508-18. PMID 23100324 DOI: 10.1093/hmg/dds449  0.48
2012 Wei T, Schubert T, Paquet-Durand F, Tanimoto N, Chang L, Koeppen K, Ott T, Griesbeck O, Seeliger MW, Euler T, Wissinger B. Light-driven calcium signals in mouse cone photoreceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6981-94. PMID 22593066 DOI: 10.1523/JNEUROSCI.6432-11.2012  0.48
2012 Trifunović D, Sahaboglu A, Kaur J, Mencl S, Zrenner E, Ueffing M, Arango-Gonzalez B, Paquet-Durand F. Neuroprotective strategies for the treatment of inherited photoreceptor degeneration. Current Molecular Medicine. 12: 598-612. PMID 22515977  0.48
2012 Fischer MD, Huber G, Paquet-Durand F, Humphries P, Redmond TM, Grimm C, Seeliger MW. In vivo assessment of rodent retinal structure using spectral domain optical coherence tomography. Advances in Experimental Medicine and Biology. 723: 489-94. PMID 22183368 DOI: 10.1007/978-1-4614-0631-0_61  0.48
2012 Sancho-Pelluz J, Paquet-Durand F. HDAC inhibition prevents Rd1 mouse photoreceptor degeneration. Advances in Experimental Medicine and Biology. 723: 107-13. PMID 22183322 DOI: 10.1007/978-1-4614-0631-0_15  0.48
2011 Kaur J, Mencl S, Sahaboglu A, Farinelli P, van Veen T, Zrenner E, Ekström P, Paquet-Durand F, Arango-Gonzalez B. Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats. Plos One. 6: e22181. PMID 21765948 DOI: 10.1371/journal.pone.0022181  0.48
2011 Paquet-Durand F, Beck S, Michalakis S, Goldmann T, Huber G, Mühlfriedel R, Trifunovi? D, Fischer MD, Fahl E, Duetsch G, Becirovic E, Wolfrum U, van Veen T, Biel M, Tanimoto N, et al. A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa. Human Molecular Genetics. 20: 941-7. PMID 21149284 DOI: 10.1093/hmg/ddq539  0.48
2010 Sancho-Pelluz J, Alavi MV, Sahaboglu A, Kustermann S, Farinelli P, Azadi S, van Veen T, Romero FJ, Paquet-Durand F, Ekström P. Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse. Cell Death & Disease. 1: e24. PMID 21364632 DOI: 10.1038/cddis.2010.4  0.48
2010 Sahaboglu A, Tanimoto N, Kaur J, Sancho-Pelluz J, Huber G, Fahl E, Arango-Gonzalez B, Zrenner E, Ekström P, Löwenheim H, Seeliger M, Paquet-Durand F. PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function. Plos One. 5: e15495. PMID 21124852 DOI: 10.1371/journal.pone.0015495  0.48
2010 Paquet-Durand F, Sanges D, McCall J, Silva J, van Veen T, Marigo V, Ekström P. Photoreceptor rescue and toxicity induced by different calpain inhibitors. Journal of Neurochemistry. 115: 930-40. PMID 20807308 DOI: 10.1111/j.1471-4159.2010.06983.x  0.48
2010 Michalakis S, Mühlfriedel R, Tanimoto N, Krishnamoorthy V, Koch S, Fischer MD, Becirovic E, Bai L, Huber G, Beck SC, Fahl E, Büning H, Paquet-Durand F, Zong X, Gollisch T, et al. Restoration of cone vision in the CNGA3-/- mouse model of congenital complete lack of cone photoreceptor function. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 2057-63. PMID 20628362 DOI: 10.1038/mt.2010.149  0.48
2010 Trifunović D, Dengler K, Michalakis S, Zrenner E, Wissinger B, Paquet-Durand F. cGMP-dependent cone photoreceptor degeneration in the cpfl1 mouse retina. The Journal of Comparative Neurology. 518: 3604-17. PMID 20593360 DOI: 10.1002/cne.22416  0.48
2009 Huber G, Beck SC, Grimm C, Sahaboglu-Tekgoz A, Paquet-Durand F, Wenzel A, Humphries P, Redmond TM, Seeliger MW, Fischer MD. Spectral domain optical coherence tomography in mouse models of retinal degeneration. Investigative Ophthalmology & Visual Science. 50: 5888-95. PMID 19661229 DOI: 10.1167/iovs.09-3724  0.48
2009 Bujakowska K, Maubaret C, Chakarova CF, Tanimoto N, Beck SC, Fahl E, Humphries MM, Kenna PF, Makarov E, Makarova O, Paquet-Durand F, Ekström PA, van Veen T, Leveillard T, Humphries P, et al. Study of gene-targeted mouse models of splicing factor gene Prpf31 implicated in human autosomal dominant retinitis pigmentosa (RP). Investigative Ophthalmology & Visual Science. 50: 5927-33. PMID 19578015 DOI: 10.1167/iovs.08-3275  0.48
2009 Podrygajlo G, Tegenge MA, Gierse A, Paquet-Durand F, Tan S, Bicker G, Stern M. Cellular phenotypes of human model neurons (NT2) after differentiation in aggregate culture. Cell and Tissue Research. 336: 439-52. PMID 19377856 DOI: 10.1007/s00441-009-0783-0  0.48
2009 Paquet-Durand F, Hauck SM, van Veen T, Ueffing M, Ekström P. PKG activity causes photoreceptor cell death in two retinitis pigmentosa models. Journal of Neurochemistry. 108: 796-810. PMID 19187097 DOI: 10.1111/j.1471-4159.2008.05822.x  0.48
2008 Sancho-Pelluz J, Arango-Gonzalez B, Kustermann S, Romero FJ, van Veen T, Zrenner E, Ekström P, Paquet-Durand F. Photoreceptor cell death mechanisms in inherited retinal degeneration. Molecular Neurobiology. 38: 253-69. PMID 18982459 DOI: 10.1007/s12035-008-8045-9  0.48
2007 Bicker G, Gierse A, Tan S, Paquet-Durand F. Simulation of stroke-related damage in cultured human nerve cells. Altex. 24: 16-8. PMID 19835047  0.48
2007 Paquet-Durand F, Bicker G. Human model neurons in studies of brain cell damage and neural repair. Current Molecular Medicine. 7: 541-54. PMID 17896991 DOI: 10.2174/156652407781695747  0.48
2007 Paquet-Durand F, Silva J, Talukdar T, Johnson LE, Azadi S, van Veen T, Ueffing M, Hauck SM, Ekström PA. Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10311-9. PMID 17881537 DOI: 10.1523/JNEUROSCI.1514-07.2007  0.48
2007 Paquet-Durand F, Johnson L, Ekström P. Calpain activity in retinal degeneration. Journal of Neuroscience Research. 85: 693-702. PMID 17171699 DOI: 10.1002/jnr.21151  0.48
2007 Azadi S, Johnson LE, Paquet-Durand F, Perez MT, Zhang Y, Ekström PA, van Veen T. CNTF+BDNF treatment and neuroprotective pathways in the rd1 mouse retina. Brain Research. 1129: 116-29. PMID 17156753 DOI: 10.1016/j.brainres.2006.10.031  0.48
2006 Paquet-Durand F, Gierse A, Bicker G. Diltiazem protects human NT-2 neurons against excitotoxic damage in a model of simulated ischemia. Brain Research. 1124: 45-54. PMID 17070504 DOI: 10.1016/j.brainres.2006.09.077  0.48
2006 Azadi S, Paquet-Durand F, Medstrand P, van Veen T, Ekström PA. Up-regulation and increased phosphorylation of protein kinase C (PKC) delta, mu and theta in the degenerating rd1 mouse retina. Molecular and Cellular Neurosciences. 31: 759-73. PMID 16503160 DOI: 10.1016/j.mcn.2006.01.001  0.48
2006 Paquet-Durand F, Azadi S, Hauck SM, Ueffing M, van Veen T, Ekström P. Calpain is activated in degenerating photoreceptors in the rd1 mouse. Journal of Neurochemistry. 96: 802-14. PMID 16405498 DOI: 10.1111/j.1471-4159.2005.03628.x  0.48
2006 Hauck SM, Ekström PA, Ahuja-Jensen P, Suppmann S, Paquet-Durand F, van Veen T, Ueffing M. Differential modification of phosducin protein in degenerating rd1 retina is associated with constitutively active Ca2+/calmodulin kinase II in rod outer segments. Molecular & Cellular Proteomics : McP. 5: 324-36. PMID 16253986 DOI: 10.1074/mcp.M500217-MCP200  0.48
2004 Paquet-Durand F, Bicker G. Hypoxic/ischaemic cell damage in cultured human NT-2 neurons. Brain Research. 1011: 33-47. PMID 15140642 DOI: 10.1016/j.brainres.2004.02.060  0.48
2003 Paquet-Durand F, Tan S, Bicker G. Turning teratocarcinoma cells into neurons: rapid differentiation of NT-2 cells in floating spheres. Brain Research. Developmental Brain Research. 142: 161-7. PMID 12711367 DOI: 10.1016/S0165-3806(03)00065-8  0.48
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