| Year |
Citation |
Score |
| 2020 |
Slotkin TA, Skavicus S, Levin ED, Seidler FJ. Paternal Δ9-Tetrahydrocannabinol Exposure Prior to Mating Elicits Deficits in Cholinergic Synaptic Function in the Offspring. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32077955 DOI: 10.1093/toxsci/kfaa004 |
0.46 |
|
| 2020 |
Hawkey AB, Glazer L, Dean C, Wells CN, Odamah KA, Slotkin TA, Seidler FJ, Levin ED. Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish. Neurotoxicology and Teratology. 106853. PMID 31911208 DOI: 10.1016/j.ntt.2019.106853 |
0.33 |
|
| 2019 |
Slotkin TA, Skavicus S, Ko A, Levin ED, Seidler FJ. PERINATAL DIAZINON EXPOSURE COMPROMISES THE DEVELOPMENT OF ACETYLCHOLINE AND SEROTONIN SYSTEMS. Toxicology. 152240. PMID 31251962 DOI: 10.1016/j.tox.2019.152240 |
0.388 |
|
| 2018 |
Cauley M, Hall BJ, Abreu-Villaça Y, Junaid S, White H, Kiany A, Slotkin TA, Levin ED. Critical developmental periods for effects of low-level tobacco smoke exposure on behavioral performance. Neurotoxicology. PMID 30036564 DOI: 10.1016/j.neuro.2018.07.012 |
0.311 |
|
| 2018 |
Slotkin TA, Ko A, Seidler FJ. Does Growth Impairment Underlie the Adverse Effects of Dexamethasone on Development of Noradrenergic Systems? Toxicology. PMID 29935188 DOI: 10.1016/j.tox.2018.06.008 |
0.342 |
|
| 2017 |
Slotkin TA, Skavicus S, Seidler FJ. Diazinon And Parathion Diverge In Their Effects On Development Of Noradrenergic Systems. Brain Research Bulletin. PMID 28235599 DOI: 10.1016/j.brainresbull.2017.02.004 |
0.449 |
|
| 2016 |
Slotkin TA, Skavicus S, Card J, Giulio RT, Seidler FJ. In vitro models reveal differences in the developmental neurotoxicity of an environmental polycylic aromatic hydrocarbon mixture compared to benzo[a]pyrene: Neuronotypic PC12 Cells and embryonic neural stem cells. Toxicology. 377: 49-56. PMID 28049045 DOI: 10.1016/j.tox.2016.12.008 |
0.305 |
|
| 2016 |
Slotkin TA, Stadler A, Skavicus S, Card J, Ruff J, Levin ED, Seidler FJ. Is There a Critical Period for the Developmental Neurotoxicity of Low-Level Tobacco Smoke Exposure? Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27633979 DOI: 10.1093/toxsci/kfw180 |
0.305 |
|
| 2015 |
Slotkin TA, Skavicus S, Seidler FJ. Prenatal drug exposures sensitize noradrenergic circuits to subsequent disruption by chlorpyrifos. Toxicology. 338: 8-16. PMID 26419632 DOI: 10.1016/j.tox.2015.09.005 |
0.431 |
|
| 2015 |
Slotkin TA, Skavicus S, Levin ED, Seidler FJ. Prenatal nicotine changes the response to postnatal chlorpyrifos: Interactions targeting serotonergic synaptic function and cognition. Brain Research Bulletin. 111: 84-96. PMID 25592617 DOI: 10.1016/j.brainresbull.2015.01.003 |
0.386 |
|
| 2015 |
Slotkin TA, Seidler FJ. Prenatal nicotine alters the developmental neurotoxicity of postnatal chlorpyrifos directed toward cholinergic systems: better, worse, or just "different?". Brain Research Bulletin. 110: 54-67. PMID 25510202 DOI: 10.1016/j.brainresbull.2014.12.003 |
0.388 |
|
| 2014 |
Levin ED, Cauley M, Johnson JE, Cooper EM, Stapleton HM, Ferguson PL, Seidler FJ, Slotkin TA. Prenatal dexamethasone augments the neurobehavioral teratology of chlorpyrifos: significance for maternal stress and preterm labor. Neurotoxicology and Teratology. 41: 35-42. PMID 24177596 DOI: 10.1016/J.Ntt.2013.10.004 |
0.412 |
|
| 2013 |
Slotkin TA, Cooper EM, Stapleton HM, Seidler FJ. Does thyroid disruption contribute to the developmental neurotoxicity of chlorpyrifos? Environmental Toxicology and Pharmacology. 36: 284-7. PMID 23686008 DOI: 10.1016/J.Etap.2013.04.003 |
0.37 |
|
| 2013 |
Slotkin TA, Card J, Infante A, Seidler FJ. BDE99 (2,2',4,4',5-pentabromodiphenyl ether) suppresses differentiation into neurotransmitter phenotypes in PC12 cells. Neurotoxicology and Teratology. 37: 13-7. PMID 23422510 DOI: 10.1016/j.ntt.2013.02.001 |
0.313 |
|
| 2013 |
Slotkin TA, Card J, Infante A, Seidler FJ. Prenatal dexamethasone augments the sex-selective developmental neurotoxicity of chlorpyrifos: implications for vulnerability after pharmacotherapy for preterm labor. Neurotoxicology and Teratology. 37: 1-12. PMID 23416428 DOI: 10.1016/j.ntt.2013.02.002 |
0.45 |
|
| 2012 |
Slotkin TA, Card J, Seidler FJ. Chlorpyrifos developmental neurotoxicity: interaction with glucocorticoids in PC12 cells. Neurotoxicology and Teratology. 34: 505-12. PMID 22796634 DOI: 10.1016/j.ntt.2012.07.002 |
0.326 |
|
| 2012 |
Levin E, Cauley M, Johnson J, Sexton H, Gordon K, Seidler F, Slotkin T. Does pharmacotherapy of preterm labor sensitize the brain to neurotoxicants? Sequential exposure to dexamethasone and chlorpyrifos Neurotoxicology and Teratology. 34: 368. DOI: 10.1016/J.Ntt.2012.05.002 |
0.314 |
|
| 2011 |
Slotkin TA, Seidler FJ. Mimicking maternal smoking and pharmacotherapy of preterm labor: fetal nicotine exposure enhances the effect of late gestational dexamethasone treatment on noradrenergic circuits. Brain Research Bulletin. 86: 435-40. PMID 21875656 DOI: 10.1016/j.brainresbull.2011.08.009 |
0.39 |
|
| 2011 |
Seidler FJ, Slotkin TA. Developmental neurotoxicity targeting hepatic and cardiac sympathetic innervation: effects of organophosphates are distinct from those of glucocorticoids. Brain Research Bulletin. 85: 225-30. PMID 21453761 DOI: 10.1016/j.brainresbull.2011.03.021 |
0.379 |
|
| 2011 |
Powers CM, Levin ED, Seidler FJ, Slotkin TA. Silver exposure in developing zebrafish produces persistent synaptic and behavioral changes. Neurotoxicology and Teratology. 33: 329-32. PMID 21035540 DOI: 10.1016/j.ntt.2010.10.006 |
0.323 |
|
| 2010 |
Adigun AA, Ryde IT, Seidler FJ, Slotkin TA. Organophosphate exposure during a critical developmental stage reprograms adenylyl cyclase signaling in PC12 cells. Brain Research. 1329: 36-44. PMID 20298678 DOI: 10.1016/J.Brainres.2010.03.025 |
0.354 |
|
| 2010 |
Levin ED, Timofeeva OA, Yang L, Petro A, Ryde IT, Wrench N, Seidler FJ, Slotkin TA. Early postnatal parathion exposure in rats causes sex-selective cognitive impairment and neurotransmitter defects which emerge in aging. Behavioural Brain Research. 208: 319-27. PMID 20015457 DOI: 10.1016/j.bbr.2009.11.007 |
0.391 |
|
| 2010 |
Slotkin TA, Ryde IT, Seidler FJ. Additive and synergistic effects of fetal nicotine and dexamethasone exposure on cholinergic synaptic function in adolescence and adulthood: Implications for the adverse consequences of maternal smoking and pharmacotherapy of preterm delivery. Brain Research Bulletin. 81: 552-60. PMID 19913076 DOI: 10.1016/j.brainresbull.2009.11.003 |
0.383 |
|
| 2010 |
Adigun AA, Wrench N, Seidler FJ, Slotkin TA. Neonatal dexamethasone treatment leads to alterations in cell signaling cascades controlling hepatic and cardiac function in adulthood. Neurotoxicology and Teratology. 32: 193-9. PMID 19853034 DOI: 10.1016/J.Ntt.2009.10.002 |
0.314 |
|
| 2009 |
Yanai J, Pinkas A, Seidler FJ, Ryde IT, Van der Zee EA, Slotkin TA. Neurobehavioral teratogenicity of sarin in an avian model. Neurotoxicology and Teratology. 31: 406-12. PMID 19660543 DOI: 10.1016/j.ntt.2009.07.007 |
0.364 |
|
| 2009 |
Slotkin TA, Wrench N, Ryde IT, Lassiter TL, Levin ED, Seidler FJ. Neonatal parathion exposure disrupts serotonin and dopamine synaptic function in rat brain regions: modulation by a high-fat diet in adulthood. Neurotoxicology and Teratology. 31: 390-9. PMID 19616088 DOI: 10.1016/j.ntt.2009.07.003 |
0.305 |
|
| 2009 |
Slotkin TA, Lassiter TL, Ryde IT, Wrench N, Levin ED, Seidler FJ. Consumption of a high-fat diet in adulthood ameliorates the effects of neonatal parathion exposure on acetylcholine systems in rat brain regions. Environmental Health Perspectives. 117: 916-22. PMID 19590683 DOI: 10.1289/ehp.0800459 |
0.384 |
|
| 2009 |
Slotkin TA, Ryde IT, Wrench N, Card JA, Seidler FJ. Nonenzymatic role of acetylcholinesterase in neuritic sprouting: regional changes in acetylcholinesterase and choline acetyltransferase after neonatal 6-hydroxydopamine lesions. Neurotoxicology and Teratology. 31: 183-6. PMID 19452616 DOI: 10.1016/j.ntt.2008.12.007 |
0.357 |
|
| 2009 |
Slotkin TA, Seidler FJ. Protein kinase C is a target for diverse developmental neurotoxicants: transcriptional responses to chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells. Brain Research. 1263: 23-32. PMID 19368821 DOI: 10.1016/j.brainres.2009.01.049 |
0.343 |
|
| 2009 |
Slotkin T, Seidler F. Transcriptional profiles reveal similarities and differences in the effects of developmental neurotoxicants on differentiation into neurotransmitter phenotypes in PC12 cells. Brain Research Bulletin. 78: 211-25. PMID 18812211 DOI: 10.1016/j.brainresbull.2008.08.021 |
0.33 |
|
| 2008 |
Slotkin TA, Bodwell BE, Ryde IT, Levin ED, Seidler FJ. Exposure of neonatal rats to parathion elicits sex-selective impairment of acetylcholine systems in brain regions during adolescence and adulthood. Environmental Health Perspectives. 116: 1308-14. PMID 18941570 DOI: 10.1289/ehp.11451 |
0.438 |
|
| 2008 |
Timofeeva OA, Sanders D, Seemann K, Yang L, Hermanson D, Regenbogen S, Agoos S, Kallepalli A, Rastogi A, Braddy D, Wells C, Perraut C, Seidler FJ, Slotkin TA, Levin ED. Persistent behavioral alterations in rats neonatally exposed to low doses of the organophosphate pesticide, parathion. Brain Research Bulletin. 77: 404-11. PMID 18817854 DOI: 10.1016/j.brainresbull.2008.08.019 |
0.418 |
|
| 2008 |
Slotkin TA, Seidler FJ, Wood CR, Lau C. Development of glucocorticoid receptor regulation in the rat forebrain: implications for adverse effects of glucocorticoids in preterm infants. Brain Research Bulletin. 76: 531-5. PMID 18534262 DOI: 10.1016/j.brainresbull.2008.03.002 |
0.379 |
|
| 2008 |
Slotkin TA, Ryde IT, Mackillop EA, Bodwell BE, Seidler FJ. Adolescent nicotine administration changes the responses to nicotine given subsequently in adulthood: adenylyl cyclase cell signaling in brain regions during nicotine administration and withdrawal, and lasting effects. Brain Research Bulletin. 76: 522-30. PMID 18534261 DOI: 10.1016/j.brainresbull.2008.03.001 |
0.301 |
|
| 2008 |
Slotkin TA, Seidler FJ, Ryde IT, Yanai J. Developmental neurotoxic effects of chlorpyrifos on acetylcholine and serotonin pathways in an avian model. Neurotoxicology and Teratology. 30: 433-9. PMID 18436430 DOI: 10.1016/j.ntt.2008.02.005 |
0.355 |
|
| 2008 |
Slotkin TA, Bodwell BE, Ryde IT, Seidler FJ. Adolescent nicotine treatment changes the response of acetylcholine systems to subsequent nicotine administration in adulthood. Brain Research Bulletin. 76: 152-65. PMID 18395624 DOI: 10.1016/j.brainresbull.2007.12.009 |
0.3 |
|
| 2008 |
Slotkin TA, Bodwell BE, Levin ED, Seidler FJ. Neonatal exposure to low doses of diazinon: long-term effects on neural cell development and acetylcholine systems. Environmental Health Perspectives. 116: 340-8. PMID 18335101 DOI: 10.1289/ehp.11005 |
0.451 |
|
| 2008 |
Roegge CS, Timofeeva OA, Seidler FJ, Slotkin TA, Levin ED. Developmental diazinon neurotoxicity in rats: later effects on emotional response. Brain Research Bulletin. 75: 166-72. PMID 18158111 DOI: 10.1016/J.Brainresbull.2007.08.008 |
0.365 |
|
| 2008 |
Timofeeva OA, Roegge CS, Seidler FJ, Slotkin TA, Levin ED. Persistent cognitive alterations in rats after early postnatal exposure to low doses of the organophosphate pesticide, diazinon. Neurotoxicology and Teratology. 30: 38-45. PMID 18096363 DOI: 10.1016/J.Ntt.2007.10.002 |
0.35 |
|
| 2007 |
Buznikov GA, Nikitina LA, Rakić LM, Milosević I, Bezuglov VV, Lauder JM, Slotkin TA. The sea urchin embryo, an invertebrate model for mammalian developmental neurotoxicity, reveals multiple neurotransmitter mechanisms for effects of chlorpyrifos: therapeutic interventions and a comparison with the monoamine depleter, reserpine. Brain Research Bulletin. 74: 221-31. PMID 17720543 DOI: 10.1016/J.Brainresbull.2007.06.012 |
0.305 |
|
| 2007 |
Slotkin TA, Ryde IT, Seidler FJ. Separate or sequential exposure to nicotine prenatally and in adulthood: persistent effects on acetylcholine systems in rat brain regions. Brain Research Bulletin. 74: 91-103. PMID 17683794 DOI: 10.1016/j.brainresbull.2007.05.007 |
0.35 |
|
| 2007 |
Slotkin TA, Ryde IT, Tate CA, Seidler FJ. Lasting effects of nicotine treatment and withdrawal on serotonergic systems and cell signaling in rat brain regions: separate or sequential exposure during fetal development and adulthood. Brain Research Bulletin. 73: 259-72. PMID 17562392 DOI: 10.1016/j.brainresbull.2007.03.012 |
0.357 |
|
| 2007 |
Slotkin TA, Seidler FJ. Comparative developmental neurotoxicity of organophosphates in vivo: transcriptional responses of pathways for brain cell development, cell signaling, cytotoxicity and neurotransmitter systems. Brain Research Bulletin. 72: 232-74. PMID 17452286 DOI: 10.1016/j.brainresbull.2007.01.005 |
0.344 |
|
| 2007 |
Zerrate MC, Pletnikov M, Connors SL, Vargas DL, Seidler FJ, Zimmerman AW, Slotkin TA, Pardo CA. Neuroinflammation and behavioral abnormalities after neonatal terbutaline treatment in rats: implications for autism. The Journal of Pharmacology and Experimental Therapeutics. 322: 16-22. PMID 17400887 DOI: 10.1124/jpet.107.121483 |
0.339 |
|
| 2007 |
Slotkin TA, Seidler FJ. Prenatal chlorpyrifos exposure elicits presynaptic serotonergic and dopaminergic hyperactivity at adolescence: critical periods for regional and sex-selective effects. Reproductive Toxicology (Elmsford, N.Y.). 23: 421-7. PMID 17267174 DOI: 10.1016/j.reprotox.2006.07.010 |
0.32 |
|
| 2007 |
Slotkin TA, MacKillop EA, Rudder CL, Ryde IT, Tate CA, Seidler FJ. Permanent, sex-selective effects of prenatal or adolescent nicotine exposure, separately or sequentially, in rat brain regions: indices of cholinergic and serotonergic synaptic function, cell signaling, and neural cell number and size at 6 months of age. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1082-97. PMID 17047666 DOI: 10.1038/sj.npp.1301231 |
0.334 |
|
| 2006 |
Slotkin TA, Levin ED, Seidler FJ. Comparative developmental neurotoxicity of organophosphate insecticides: effects on brain development are separable from systemic toxicity. Environmental Health Perspectives. 114: 746-51. PMID 16675431 DOI: 10.1289/ehp.8828 |
0.376 |
|
| 2006 |
Jameson RR, Seidler FJ, Qiao D, Slotkin TA. Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells. Environmental Health Perspectives. 114: 667-72. PMID 16675418 DOI: 10.1289/ehp.8750 |
0.361 |
|
| 2006 |
Slotkin TA, Pinkerton KE, Seidler FJ. Perinatal environmental tobacco smoke exposure in rhesus monkeys: Critical periods and regional selectivity for effects on brain cell development and lipid peroxidation Environmental Health Perspectives. 114: 34-39. PMID 16393655 DOI: 10.1289/ehp.8286 |
0.334 |
|
| 2006 |
Kreider ML, Tate CA, Cousins MM, Oliver CA, Seidler FJ, Slotkin TA. Lasting effects of developmental dexamethasone treatment on neural cell number and size, synaptic activity, and cell signaling: critical periods of vulnerability, dose-effect relationships, regional targets, and sex selectivity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 12-35. PMID 15920497 DOI: 10.1038/sj.npp.1300783 |
0.396 |
|
| 2006 |
Roegge C, Timofeva O, Seidler F, Slotkin TA, Levin ED. Persisting effects of early postnatal diazinon exposure on emotional reactivity in rats Neurotoxicology and Teratology. 28: 709. DOI: 10.1016/J.Ntt.2006.09.015 |
0.304 |
|
| 2005 |
Garcia SJ, Seidler FJ, Slotkin TA. Developmental neurotoxicity of chlorpyrifos: targeting glial cells. Environmental Toxicology and Pharmacology. 19: 455-61. PMID 21783512 DOI: 10.1016/J.Etap.2004.12.007 |
0.444 |
|
| 2005 |
Slikker W, Xu ZA, Levin ED, Slotkin TA. Mode of action: disruption of brain cell replication, second messenger, and neurotransmitter systems during development leading to cognitive dysfunction--developmental neurotoxicity of nicotine. Critical Reviews in Toxicology. 35: 703-11. PMID 16417037 DOI: 10.1080/10408440591007421 |
0.327 |
|
| 2005 |
Slotkin TA, Tate CA, Cousins MM, Seidler FJ. Imbalances emerge in cardiac autonomic cell signaling after neonatal exposure to terbutaline or chlorpyrifos, alone or in combination. Brain Research. Developmental Brain Research. 160: 219-30. PMID 16256208 DOI: 10.1016/j.devbrainres.2005.09.006 |
0.337 |
|
| 2005 |
Slotkin TA, Brown KK, Seidler FJ. Developmental exposures of rats to chlorpyrifos elicits sex-selective hyperlipidemia and hyperinsulinemia in adulthood Environmental Health Perspectives. 113: 1291-1294. PMID 16203236 DOI: 10.1289/ehp.8133 |
0.368 |
|
| 2005 |
Aldridge JE, Meyer A, Seidler FJ, Slotkin TA. Alterations in central nervous system serotonergic and dopaminergic synaptic activity in adulthood after prenatal or neonatal chlorpyrifos exposure. Environmental Health Perspectives. 113: 1027-31. PMID 16079074 DOI: 10.1289/Ehp.7968 |
0.352 |
|
| 2005 |
Slotkin TA, Seidler FJ. The alterations in CNS serotonergic mechanisms caused by neonatal chlorpyrifos exposure are permanent Developmental Brain Research. 158: 115-119. PMID 16024092 DOI: 10.1016/j.devbrainres.2005.06.008 |
0.331 |
|
| 2005 |
Slotkin TA, Oliver CA, Seidler FJ. Critical periods for the role of oxidative stress in the developmental neurotoxicity of chlorpyrifos and terbutaline, alone or in combination. Brain Research. Developmental Brain Research. 157: 172-80. PMID 15963356 DOI: 10.1016/j.devbrainres.2005.04.001 |
0.427 |
|
| 2005 |
Kreider ML, Aldridge JE, Cousins MM, Oliver CA, Seidler FJ, Slotkin TA. Disruption of rat forebrain development by glucocorticoids: critical perinatal periods for effects on neural cell acquisition and on cell signaling cascades mediating noradrenergic and cholinergic neurotransmitter/neurotrophic responses. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1841-55. PMID 15841102 DOI: 10.1038/Sj.Npp.1300743 |
0.437 |
|
| 2005 |
Roy TS, Sharma V, Seidler FJ, Slotkin TA. Quantitative morphological assessment reveals neuronal and glial deficits in hippocampus after a brief subtoxic exposure to chlorpyrifos in neonatal rats. Brain Research. Developmental Brain Research. 155: 71-80. PMID 15763277 DOI: 10.1016/j.devbrainres.2004.12.004 |
0.377 |
|
| 2005 |
Meyer A, Seidler FJ, Aldridge JE, Slotkin TA. Developmental exposure to terbutaline alters cell signaling in mature rat brain regions and augments the effects of subsequent neonatal exposure to the organophosphorus insecticide chlorpyrifos. Toxicology and Applied Pharmacology. 203: 154-66. PMID 15710176 DOI: 10.1016/J.Taap.2004.08.005 |
0.418 |
|
| 2005 |
Beer A, Slotkin TA, Seidler FJ, Aldridge JE, Yanai J. Nicotine therapy in adulthood reverses the synaptic and behavioral deficits elicited by prenatal exposure to phenobarbital. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 156-65. PMID 15496940 DOI: 10.1038/Sj.Npp.1300582 |
0.349 |
|
| 2005 |
Slotkin TA, Seidler FJ, Qiao D, Aldridge JE, Tate CA, Cousins MM, Proskocil BJ, Sekhon HS, Clark JA, Lupo SL, Spindel ER. Effects of prenatal nicotine exposure on primate brain development and attempted amelioration with supplemental choline or vitamin C: neurotransmitter receptors, cell signaling and cell development biomarkers in fetal brain regions of rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 129-44. PMID 15316571 DOI: 10.1038/Sj.Npp.1300544 |
0.301 |
|
| 2004 |
Yanai J, Beer A, Huleihel R, Izrael M, Katz S, Levi Y, Rozenboim I, Yaniv SP, Slotkin TA. Convergent effects on cell signaling mechanisms mediate the actions of different neurobehavioral teratogens: alterations in cholinergic regulation of protein kinase C in chick and avian models. Annals of the New York Academy of Sciences. 1025: 595-601. PMID 15542768 DOI: 10.1196/annals.1316.074 |
0.322 |
|
| 2004 |
Slotkin TA, Southard MC, Adam SJ, Cousins MM, Seidler FJ. α7 Nicotinic acetylcholine receptors targeted by cholinergic developmental neurotoxicants: Nicotine and chlorpyrifos Brain Research Bulletin. 64: 227-235. PMID 15464859 DOI: 10.1016/j.brainresbull.2004.07.005 |
0.303 |
|
| 2004 |
Kreider ML, Seidler FJ, Cousins MM, Tate CA, Slotkin TA. Transiently overexpressed alpha2-adrenoceptors and their control of DNA synthesis in the developing brain. Brain Research. Developmental Brain Research. 152: 233-9. PMID 15351511 DOI: 10.1016/j.devbrainres.2004.07.001 |
0.34 |
|
| 2004 |
Slotkin TA. Cholinergic systems in brain development and disruption by neurotoxicants: Nicotine, environmental tobacco smoke, organophosphates Toxicology and Applied Pharmacology. 198: 132-151. PMID 15236950 DOI: 10.1016/j.taap.2003.06.001 |
0.36 |
|
| 2004 |
Vatury O, Barg J, Slotkin TA, Yanai J. Altered localization of choline transporter sites in the mouse hippocampus after prenatal heroin exposure Brain Research Bulletin. 63: 25-32. PMID 15121236 DOI: 10.1016/j.brainresbull.2003.11.004 |
0.354 |
|
| 2004 |
Icenogle LM, Christopher NC, Blackwelder WP, Caldwell DP, Qiao D, Seidler FJ, Slotkin TA, Levin ED. Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation. Neurotoxicology and Teratology. 26: 95-101. PMID 15001218 DOI: 10.1016/j.ntt.2003.09.001 |
0.377 |
|
| 2004 |
Meyer A, Seidler FJ, Aldridge JE, Tate CA, Cousins MM, Slotkin TA. Critical periods for chlorpyrifos-induced developmental neurotoxicity: alterations in adenylyl cyclase signaling in adult rat brain regions after gestational or neonatal exposure. Environmental Health Perspectives. 112: 295-301. PMID 14998743 DOI: 10.1289/Ehp.6755 |
0.426 |
|
| 2004 |
Rhodes MC, Seidler FJ, Qiao D, Tate CA, Cousins MM, Slotkin TA. Does pharmacotherapy for preterm labor sensitize the developing brain to environmental neurotoxicants? Cellular and synaptic effects of sequential exposure to terbutaline and chlorpyrifos in neonatal rats. Toxicology and Applied Pharmacology. 195: 203-17. PMID 14998686 DOI: 10.1016/j.taap.2003.11.008 |
0.496 |
|
| 2004 |
Roy TS, Seidler FJ, Slotkin TA. Morphologic effects of subtoxic neonatal chlorpyrifos exposure in developing rat brain: Regionally selective alterations in neurons and glia Developmental Brain Research. 148: 197-206. PMID 14766197 DOI: 10.1016/j.devbrainres.2003.12.004 |
0.415 |
|
| 2004 |
Qiao D, Seidler FJ, Abreu-Villaça Y, Tate CA, Cousins MM, Slotkin TA. Chlorpyrifos exposure during neurulation: cholinergic synaptic dysfunction and cellular alterations in brain regions at adolescence and adulthood. Brain Research. Developmental Brain Research. 148: 43-52. PMID 14757517 DOI: 10.1016/j.devbrainres.2003.10.004 |
0.461 |
|
| 2004 |
Meyer A, Seidler FJ, Slotkin TA. Developmental effects of chlorpyrifos extend beyond neurotoxicity: Critical periods for immediate and delayed-onset effects on cardiac and hepatic cell signaling Environmental Health Perspectives. 112: 170-178. PMID 14754571 |
0.345 |
|
| 2004 |
Rhodes MC, Seidler FJ, Abdel-Rahman A, Tate CA, Nyska A, Rincavage HL, Slotkin TA. Terbutaline is a developmental neurotoxicant: effects on neuroproteins and morphology in cerebellum, hippocampus, and somatosensory cortex. The Journal of Pharmacology and Experimental Therapeutics. 308: 529-37. PMID 14610225 DOI: 10.1124/jpet.103.060095 |
0.39 |
|
| 2003 |
Xu Z, Seidler FJ, Tate CA, Garcia SJ, Slikker W, Slotkin TA. Sex-selective hippocampal alterations after adolescent nicotine administration: effects on neurospecific proteins. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 5: 955-60. PMID 14668080 DOI: 10.1080/14622200310001615321 |
0.341 |
|
| 2003 |
Navarro HA, Basta PV, Seidler FJ, Slotkin TA. Short-term adolescent nicotine exposure in rats elicits immediate and delayed deficits in T-lymphocyte function: Critical periods, patterns of exposure, dose thresholds Nicotine and Tobacco Research. 5: 859-868. PMID 14668069 DOI: 10.1080/14622200310001614610 |
0.338 |
|
| 2003 |
Meyer A, Seidler FJ, Cousins MM, Slotkin TA. Developmental neurotoxicity elicited by gestational exposure to chlorpyrifos: When is adenylyl cyclase a target? Environmental Health Perspectives. 111: 1871-1876. PMID 14644659 DOI: 10.1289/EHP.6468 |
0.352 |
|
| 2003 |
Abreu-Villaça Y, Seidler FJ, Slotkin TA. Impact of adolescent nicotine exposure on adenylyl cyclase-mediated cell signaling: Enzyme induction, neurotransmitter-specific effects, regional selectivities, and the role of withdrawal Brain Research. 988: 164-172. PMID 14519538 DOI: 10.1016/S0006-8993(03)03368-7 |
0.315 |
|
| 2003 |
Slotkin TA, Seidler FJ, Yanai J. Heroin neuroteratogenicity: Delayed-onset deficits in catecholaminergic synaptic activity Brain Research. 984: 189-197. PMID 12932853 DOI: 10.1016/S0006-8993(03)03152-4 |
0.331 |
|
| 2003 |
Slotkin TA, Freibaum BD, Tate CA, Thillai I, Ferguson SA, Cada AM, Seidler FJ. Long-lasting CNS effects of a short-term chemical knockout of ornithine decarboxylase during development: nicotinic cholinergic receptor upregulation and subtle macromolecular changes in adulthood. Brain Research. 981: 118-25. PMID 12885432 DOI: 10.1016/S0006-8993(03)02993-7 |
0.391 |
|
| 2003 |
Abreu-Villaça Y, Seidler FJ, Tate CA, Slotkin TA. Nicotine is a neurotoxin in the adolescent brain: critical periods, patterns of exposure, regional selectivity, and dose thresholds for macromolecular alterations. Brain Research. 979: 114-28. PMID 12850578 DOI: 10.1016/S0006-8993(03)02885-3 |
0.361 |
|
| 2003 |
Abreu-Villaça Y, Seidler FJ, Qiao D, Tate CA, Cousins MM, Thillai I, Slotkin TA. Short-term adolescent nicotine exposure has immediate and persistent effects on cholinergic systems: critical periods, patterns of exposure, dose thresholds. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1935-49. PMID 12784097 DOI: 10.1038/sj.npp.1300221 |
0.377 |
|
| 2003 |
Qiao D, Seidler FJ, Tate CA, Cousins MM, Slotkin TA. Fetal chlorpyrifos exposure: adverse effects on brain cell development and cholinergic biomarkers emerge postnatally and continue into adolescence and adulthood. Environmental Health Perspectives. 111: 536-44. PMID 12676612 DOI: 10.1289/ehp.5828 |
0.441 |
|
| 2003 |
Garcia SJ, Seidler FJ, Slotkin TA. Developmental neurotoxicity elicited by prenatal or postnatal chlorpyrifos exposure: effects on neurospecific proteins indicate changing vulnerabilities. Environmental Health Perspectives. 111: 297-303. PMID 12611658 DOI: 10.1289/Ehp.5791 |
0.443 |
|
| 2003 |
Shahak H, Slotkin TA, Yanai J. Alterations in PKCγ in the mouse hippocampus after prenatal exposure to heroin: A link from cell signaling to behavioral outcome Developmental Brain Research. 140: 117-125. PMID 12524182 DOI: 10.1016/S0165-3806(02)00607-7 |
0.342 |
|
| 2003 |
Garofolo MC, Seidler FJ, Cousins MM, Tate CA, Qiao D, Slotkin TA. Developmental toxicity of terbutaline: critical periods for sex-selective effects on macromolecules and DNA synthesis in rat brain, heart, and liver. Brain Research Bulletin. 59: 319-29. PMID 12464406 DOI: 10.1016/S0361-9230(02)00925-5 |
0.377 |
|
| 2003 |
Dam K, Seidler FJ, Slotkin TA. Transcriptional biomarkers distinguish between vulnerable periods for developmental neurotoxicity of chlorpyrifos: Implications for toxicogenomics. Brain Research Bulletin. 59: 261-5. PMID 12464398 DOI: 10.1016/S0361-9230(02)00874-2 |
0.666 |
|
| 2002 |
Levin ED, Addy N, Baruah A, Elias A, Christopher NC, Seidler FJ, Slotkin TA. Prenatal chlorpyrifos exposure in rats causes persistent behavioral alterations. Neurotoxicology and Teratology. 24: 733-41. PMID 12460655 DOI: 10.1016/S0892-0362(02)00272-6 |
0.391 |
|
| 2002 |
Qiao D, Seidler FJ, Padilla S, Slotkin TA. Developmental neurotoxicity of chlorpyrifos: what is the vulnerable period? Environmental Health Perspectives. 110: 1097-103. PMID 12417480 DOI: 10.1289/ehp.021101097 |
0.395 |
|
| 2002 |
Slotkin TA, Tate CA, Cousins MM, Seidler FJ. Functional alterations in CNS catecholamine systems in adolescence and adulthood after neonatal chlorpyrifos exposure. Brain Research. Developmental Brain Research. 133: 163-73. PMID 11882346 DOI: 10.1016/S0165-3806(02)00284-5 |
0.433 |
|
| 2002 |
Garcia SJ, Seidler FJ, Qiao D, Slotkin TA. Chlorpyrifos targets developing glia: effects on glial fibrillary acidic protein. Brain Research. Developmental Brain Research. 133: 151-61. PMID 11882345 DOI: 10.1016/S0165-3806(02)00283-3 |
0.425 |
|
| 2002 |
Roy TS, Seidler FJ, Slotkin TA. Prenatal nicotine exposure evokes alterations of cell structure in hippocampus and somatosensory cortex Journal of Pharmacology and Experimental Therapeutics. 300: 124-133. PMID 11752107 DOI: 10.1124/jpet.300.1.124 |
0.356 |
|
| 2001 |
Navarro HA, Basta PV, Seidler FJ, Slotkin TA. Neonatal chlorpyrifos administration elicits deficits in immune function in adulthood: A neural effect? Developmental Brain Research. 130: 249-252. PMID 11675126 DOI: 10.1016/S0165-3806(01)00254-1 |
0.375 |
|
| 2001 |
Xu Z, Seidler FJ, Ali SF, Slikker W, Slotkin TA. Fetal and adolescent nicotine administration: effects on CNS serotonergic systems. Brain Research. 914: 166-78. PMID 11578609 DOI: 10.1016/S0006-8993(01)02797-4 |
0.301 |
|
| 2001 |
Levin ED, Addy N, Nakajima A, Christopher NC, Seidler FJ, Slotkin TA. Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats. Brain Research. Developmental Brain Research. 130: 83-9. PMID 11557096 DOI: 10.1016/S0165-3806(01)00215-2 |
0.392 |
|
| 2001 |
Raines KW, Seidler FJ, Slotkin TA. Alterations in serotonin transporter expression in brain regions of rats exposed neonatally to chlorpyrifos Developmental Brain Research. 130: 65-72. PMID 11557094 DOI: 10.1016/S0165-3806(01)00211-5 |
0.323 |
|
| 2001 |
Slotkin TA, Cousins MM, Tate CA, Seidler FJ. Persistent cholinergic presynaptic deficits after neonatal chlorpyrifos exposure. Brain Research. 902: 229-43. PMID 11384617 DOI: 10.1016/S0006-8993(01)02387-3 |
0.519 |
|
| 2001 |
Slotkin TA, Pinkerton KE, Garofolo MC, Auman JT, McCook EC, Seidler FJ. Perinatal exposure to environmental tobacco smoke induces adenylyl cyclase and alters receptor-mediated cell signaling in brain and heart of neonatal rats. Brain Research. 898: 73-81. PMID 11292450 DOI: 10.1016/S0006-8993(01)02145-X |
0.303 |
|
| 2001 |
Trauth JA, Seidler FJ, Ali SF, Slotkin TA. Adolescent nicotine exposure produces immediate and long-term changes in CNS noradrenergic and dopaminergic function. Brain Research. 892: 269-80. PMID 11172774 DOI: 10.1016/S0006-8993(00)03227-3 |
0.351 |
|
| 2001 |
Garcia SJ, Seidler FJ, Crumpton TL, Slotkin TA. Does the developmental neurotoxicity of chlorpyrifos involve glial targets? Macromolecule synthesis, adenylyl cyclase signaling, nuclear transcription factors, and formation of reactive oxygen in C6 glioma cells. Brain Research. 891: 54-68. PMID 11164809 DOI: 10.1016/S0006-8993(00)03189-9 |
0.329 |
|
| 2000 |
Slotkin TA, Ferguson SA, Cada AM, McCook EC, Seidler FJ. Neonatal polyamine depletion by α-difluoromethylornithine: Effects on adenylyl cyclase cell signaling are separable from effects on brain region growth Brain Research. 887: 16-22. PMID 11134585 DOI: 10.1016/S0006-8993(00)02961-9 |
0.365 |
|
| 2000 |
Trauth JA, Seidler FJ, Slotkin TA. Persistent and delayed behavioral changes after nicotine treatment in adolescent rats. Brain Research. 880: 167-72. PMID 11033001 DOI: 10.1016/S0006-8993(00)02823-7 |
0.345 |
|
| 2000 |
Steingart RA, Abu-Roumi M, Newman ME, Silverman WF, Slotkin TA, Yanai J. Neurobehavioral damage to cholinergic systems caused by prenatal exposure to heroin or phenobarbital: cellular mechanisms and the reversal of deficits by neural grafts. Brain Research. Developmental Brain Research. 122: 125-33. PMID 10960681 DOI: 10.1016/S0165-3806(00)00063-8 |
0.321 |
|
| 2000 |
Trauth JA, McCook EC, Seidler FJ, Slotkin TA. Modeling adolescent nicotine exposure: effects on cholinergic systems in rat brain regions. Brain Research. 873: 18-25. PMID 10915806 DOI: 10.1016/S0006-8993(00)02465-3 |
0.336 |
|
| 2000 |
Dam K, Seidler FJ, Slotkin TA. Chlorpyrifos exposure during a critical neonatal period elicits gender-selective deficits in the development of coordination skills and locomotor activity. Brain Research. Developmental Brain Research. 121: 179-87. PMID 10876030 DOI: 10.1016/S0165-3806(00)00044-4 |
0.678 |
|
| 2000 |
Trauth JA, Seidler FJ, Slotkin TA. An animal model of adolescent nicotine exposure: effects on gene expression and macromolecular constituents in rat brain regions. Brain Research. 867: 29-39. PMID 10837795 DOI: 10.1016/S0006-8993(00)02208-3 |
0.381 |
|
| 2000 |
Crumpton TL, Seidler FJ, Slotkin TA. Developmental neurotoxicity of chlorpyrifos in vivo and in vitro: Effects on nuclear transcription factors involved in cell replication and differentiation Brain Research. 857: 87-98. PMID 10700556 DOI: 10.1016/S0006-8993(99)02357-4 |
0.324 |
|
| 1999 |
Trauth JA, Seidler FJ, McCook EC, Slotkin TA. Adolescent nicotine exposure causes persistent upregulation of nicotinic cholinergic receptors in rat brain regions. Brain Research. 851: 9-19. PMID 10642823 DOI: 10.1016/S0006-8993(99)01994-0 |
0.355 |
|
| 1999 |
Dam K, Seidler FJ, Slotkin TA. Chlorpyrifos releases norepinephrine from adult and neonatal rat brain synaptosomes. Brain Research. Developmental Brain Research. 118: 129-33. PMID 10611511 DOI: 10.1016/S0165-3806(99)00139-X |
0.668 |
|
| 1999 |
Dam K, Garcia SJ, Seidler FJ, Slotkin TA. Neonatal chlorpyrifos exposure alters synaptic development and neuronal activity in cholinergic and catecholaminergic pathways. Brain Research. Developmental Brain Research. 116: 9-20. PMID 10446342 DOI: 10.1016/S0165-3806(99)00067-X |
0.682 |
|
| 1999 |
Slotkin TA. Developmental cholinotoxicants: Nicotine and chlorpyrifos Environmental Health Perspectives. 107: 71-80. PMID 10229709 DOI: 10.1289/ehp.99107s171 |
0.342 |
|
| 1999 |
Trauth JA, Seidler FJ, McCook EC, Slotkin TA. Persistent c-fos induction by nicotine in developing rat brain regions: interaction with hypoxia. Pediatric Research. 45: 38-45. PMID 9890606 DOI: 10.1203/00006450-199901000-00007 |
0.389 |
|
| 1998 |
Slotkin TA, Zhang J, McCook EC, Seidler FJ. Glucocorticoid administration alters nuclear transcription factors in fetal rat brain: implications for the use of antenatal steroids. Brain Research. Developmental Brain Research. 111: 11-24. PMID 9804869 DOI: 10.1016/S0165-3806(98)00115-1 |
0.355 |
|
| 1998 |
Roy TS, Andrews JE, Seidler FJ, Slotkin TA. Chlorpyrifos elicits mitotic abnormalities and apoptosis in neuroepithelium of cultured rat embryos. Teratology. 58: 62-8. PMID 9787407 DOI: 10.1002/(SICI)1096-9926(199808)58:2<62::AID-TERA7>3.0.CO;2-2 |
0.351 |
|
| 1998 |
Song X, Violin JD, Seidler FJ, Slotkin TA. Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells. Toxicology and Applied Pharmacology. 151: 182-91. PMID 9705902 DOI: 10.1006/taap.1998.8424 |
0.365 |
|
| 1998 |
Dam K, Seidler FJ, Slotkin TA. Developmental neurotoxicity of chlorpyrifos: delayed targeting of DNA synthesis after repeated administration. Brain Research. Developmental Brain Research. 108: 39-45. PMID 9693782 DOI: 10.1016/S0165-3806(98)00028-5 |
0.682 |
|
| 1998 |
McGrath KE, Seidler FJ, Slotkin TA. Convergent control of serotonin transporter expression by glucocorticoids and cocaine in fetal and neonatal rat brain. Brain Research. Developmental Brain Research. 104: 209-13. PMID 9466725 DOI: 10.1016/S0165-3806(97)00144-2 |
0.329 |
|
| 1998 |
Johnson DE, Seidler FJ, Slotkin TA. Early biochemical detection of delayed neurotoxicity resulting from developmental exposure to chloropyrifos. Brain Research Bulletin. 45: 143-7. PMID 9443830 DOI: 10.1016/S0361-9230(97)00329-8 |
0.442 |
|
| 1997 |
Campbell CG, Seidler FJ, Slotkin TA. Chlorpyrifos interferes with cell development in rat brain regions. Brain Research Bulletin. 43: 179-89. PMID 9222531 DOI: 10.1016/S0361-9230(96)00436-4 |
0.398 |
|
| 1997 |
Song X, Seidler FJ, Saleh JL, Zhang J, Padilla S, Slotkin TA. Cellular mechanisms for developmental toxicity of chlorpyrifos: targeting the adenylyl cyclase signaling cascade. Toxicology and Applied Pharmacology. 145: 158-74. PMID 9221834 DOI: 10.1006/taap.1997.8171 |
0.372 |
|
| 1997 |
Zeiders JL, Seidler FJ, Slotkin TA. Ontogeny of regulatory mechanisms for beta-adrenoceptor control of rat cardiac adenylyl cyclase: targeting of G-proteins and the cyclase catalytic subunit. Journal of Molecular and Cellular Cardiology. 29: 603-15. PMID 9140819 DOI: 10.1006/jmcc.1996.0303 |
0.303 |
|
| 1997 |
Slotkin TA. Cryptic brain cell injury caused by fetal nicotine exposure is associated with persistent elevations of c-fos protooncogene expression Brain Research. 750: 180-188. PMID 9098543 DOI: 10.1016/S0006-8993(96)01345-5 |
0.37 |
|
| 1996 |
Tolson CM, Seidler FJ, McCook EC, Slotkin TA. Does concurrent or prior nicotine exposure interact with neonatal hypoxia to produce cardiac cell damage? Teratology. 52: 298-305. PMID 8838253 DOI: 10.1002/tera.1420520508 |
0.362 |
|
| 1996 |
Slotkin TA, Barnes GA, McCook EC, Seidler FJ. Programming of brainstem serotonin transporter development by prenatal glucocorticoids Developmental Brain Research. 93: 155-161. PMID 8804702 DOI: 10.1016/0165-3806(96)00027-2 |
0.322 |
|
| 1995 |
Whitney KD, Seidler FJ, Slotkin TA. Developmental neurotoxicity of chlorpyrifos: cellular mechanisms. Toxicology and Applied Pharmacology. 134: 53-62. PMID 7545834 DOI: 10.1006/taap.1995.1168 |
0.429 |
|
| 1994 |
Slotkin TA, Lau C, Mccook EC, Lappi SE, Seidler FJ. Glucocorticoids Enhance Intracellular Signaling via Adenylate Cyclase at Three Distinct Loci in the Fetus: A Mechanism for Heterologous Teratogenic Sensitization? Toxicology and Applied Pharmacology. 127: 64-75. PMID 8048055 DOI: 10.1006/taap.1994.1140 |
0.32 |
|
| 1994 |
Seidler FJ, Albright ES, Lappi SE, Slotkin TA. In search of a mechanism for receptor-mediated neurobehavioral teratogenesis by nicotine: catecholamine release by nicotine in immature rat brain regions Developmental Brain Research. 82: 1-8. PMID 7842497 DOI: 10.1016/0165-3806(94)90142-2 |
0.334 |
|
| 1993 |
Zahalka EA, Seidler FJ, Yanai J, Slotkin TA. Fetal nicotine exposure alters ontogeny of M1-receptors and their link to G-proteins. Neurotoxicology and Teratology. 15: 107-15. PMID 8510605 DOI: 10.1016/0892-0362(93)90069-Z |
0.337 |
|
| 1993 |
Slotkin TA, Lappi SE, Seidler FJ. Impact of fetal nicotine exposure on development of rat brain regions: Critical sensitive periods or effects of withdrawal? Brain Research Bulletin. 31: 319-328. PMID 8490731 DOI: 10.1016/0361-9230(93)90224-Y |
0.401 |
|
| 1993 |
Zahalka EA, Seidler FJ, Lappi SE, Yanai J, Slotkin TA. Differential development of cholinergic nerve terminal markers in rat brain regions: implications for nerve terminal density, impulse activity and specific gene expression Brain Research. 601: 221-229. PMID 8431769 DOI: 10.1016/0006-8993(93)91714-4 |
0.344 |
|
| 1993 |
Seidler FJ, Slotkin TA. Prenatal cocaine and cell development in rat brain regions: Effects on ornithine decarboxylase and macromolecules Brain Research Bulletin. 30: 91-99. PMID 8420640 DOI: 10.1016/0361-9230(93)90043-B |
0.348 |
|
| 1993 |
Slotkin TA, McCook EC, Seidler FJ. Glucocorticoids regulate the development of intracellular signaling: enhanced forebrain adenylate cyclase catalytic subunit activity after fetal dexamethasone exposure. Brain Research Bulletin. 32: 359-64. PMID 8221125 DOI: 10.1016/0361-9230(93)90200-U |
0.346 |
|
| 1992 |
Carlos RQ, Seidler FJ, Slotkin TA. Fetal dexamethasone exposure sensitizes neonatal rat brain to hypoxia: effects on protein and DNA synthesis. Brain Research. Developmental Brain Research. 64: 161-6. PMID 1786639 DOI: 10.1016/0165-3806(91)90220-D |
0.404 |
|
| 1992 |
Carlos RQ, Seidler FJ, Slotkin TA. Fetal dexamethasone exposure alters macromolecular characteristics of rat brain development: a critical period for regionally selective alterations? Teratology. 46: 45-59. PMID 1641811 DOI: 10.1002/tera.1420460108 |
0.342 |
|
| 1992 |
Zahalka EA, Seidler FJ, Lappi SE, Mccook EC, Yanai J, Slotkin TA. Deficits in development of central cholinergic pathways caused by fetal nicotine exposure: Differential effects on choline acetyltransferase activity and [3H]hemicholinium-3 binding Neurotoxicology and Teratology. 14: 375-382. PMID 1488031 DOI: 10.1016/0892-0362(92)90047-E |
0.433 |
|
| 1992 |
Seidler FJ, Levin ED, Lappi SE, Slotkin TA. Fetal nicotine exposure ablates the ability of postnatal nicotine challenge to release norepinephrine from rat brain regions. Brain Research. Developmental Brain Research. 69: 288-91. PMID 1424104 DOI: 10.1016/0165-3806(92)90170-2 |
0.391 |
|
| 1992 |
Slotkin TA, McCook EC, Lappi SE, Seidler FJ. Altered development of basal and forskolin-stimulated adenylate cyclase activity in brain regions of rats exposed to nicotine prenatally Developmental Brain Research. 68: 233-239. PMID 1394969 DOI: 10.1016/0165-3806(92)90065-5 |
0.344 |
|
| 1992 |
Slotkin TA, Lappi SE, McCook EC, Tayyeb MI, Eylers JP, Seidlcr FJ. Glucocorticoids and the development of neuronal function: Effects of prenatal dexamethasone exposure on central noradrenergic activity Neonatology. 61: 326-336. PMID 1391259 DOI: 10.1159/000243761 |
0.425 |
|
| 1991 |
Slotkin TA, Navarro HA, McCook EC, Seidler FJ. Fetal nicotine exposure produces postnatal up-regulation of adenylate cyclase activity in peripheral tissues. Life Sciences. 47: 1561-7. PMID 2174490 DOI: 10.1016/0024-3205(90)90185-T |
0.301 |
|
| 1991 |
Carlos RQ, Seidler FJ, Lappi SE, Slotkin TA. Fetal dexamethasone exposure affects basal ornithine decarboxylase activity in developing rat brain regions and alters acute responses to hypoxia and maternal separation Neonatology. 59: 69-77. PMID 2036470 DOI: 10.1159/000243325 |
0.443 |
|
| 1991 |
McFarland BJ, Seidler FJ, Slotkin TA. Inhibition of DNA synthesis in neonatal rat brain regions caused by acute nicotine administration Developmental Brain Research. 58: 223-229. PMID 2029766 DOI: 10.1016/0165-3806(91)90008-7 |
0.351 |
|
| 1991 |
Slotkin TA, Lappi SE, Tayyeb MI, Seidler FJ. Chronic prenatal nicotine exposure sensitizes rat brain to acute postnatal nicotine challenge as assessed with ornithine decarboxylase Life Sciences. 49: 665-670. PMID 1865760 DOI: 10.1016/0024-3205(91)90113-P |
0.316 |
|
| 1991 |
Smith IV WT, Seidler FJ, Slotkin TA. Acute stimulation of ornithine decarboxylase in neonatal rat brain regions by nicotine: a central receptor-mediated process? Developmental Brain Research. 63: 85-93. PMID 1790600 DOI: 10.1016/0165-3806(91)90069-U |
0.319 |
|
| 1991 |
Wagner JP, Seidler FJ, Slotkin TA. Presynaptic input regulates development of beta-adrenergic control of rat brain ornithine decarboxylase: effects of 6-hydroxydopamine or propranolol. Brain Research Bulletin. 26: 885-90. PMID 1657319 DOI: 10.1016/0361-9230(91)90253-G |
0.318 |
|
| 1990 |
Duncan CP, Seidler FJ, Lappi SE, Slotkin TA. Dual control of DNA synthesis by alpha- and beta-adrenergic mechanisms in normoxic and hypoxic neonatal rat brain. Brain Research. Developmental Brain Research. 55: 29-33. PMID 2170056 DOI: 10.1016/0165-3806(90)90102-5 |
0.314 |
|
| 1990 |
Seidler FJ, Slotkin TA. Effects of acute hypoxia on neonatal rat brain: Regionally selective, long-term alterations in catecholamine levels and turnover Brain Research Bulletin. 24: 157-161. PMID 2157528 DOI: 10.1016/0361-9230(90)90200-J |
0.377 |
|
| 1990 |
Seidler FJ, Bell JM, Slotkin TA. Undernutrition and overnutrition in the neonatal rat: long-term effects on noradrenergic pathways in brain regions. Pediatric Research. 27: 191-7. PMID 2156213 DOI: 10.1203/00006450-199002000-00021 |
0.39 |
|
| 1990 |
Lau C, Cameron A, Antolick L, Slotkin TA. Trophic control of the ornithine decarboxylase/polyamine system in neonatal rat brain regions: lesions caused by 6-hydroxydopamine produce effects selective for cerebellum Developmental Brain Research. 52: 167-173. PMID 2110039 DOI: 10.1016/0165-3806(90)90232-N |
0.37 |
|
| 1989 |
Slotkin TA, Windh R, Whitmore WL, Seidler FJ. Adrenergic control of DNA synthesis in developing rat brain regions: effects of intracisternal administration of isoproterenol. Brain Research Bulletin. 21: 737-40. PMID 3219605 DOI: 10.1016/0361-9230(88)90040-8 |
0.353 |
|
| 1989 |
Navarro HA, Seidler FJ, Schwartz RD, Baker FE, Dobbins SS, Slotkin TA. Prenatal exposure to nicotine impairs nervous system development at a dose which does not affect viability or growth. Brain Research Bulletin. 23: 187-92. PMID 2819477 DOI: 10.1016/0361-9230(89)90146-9 |
0.361 |
|
| 1989 |
Slotkin TA, Baker FE, Dobbins SS, Eylers JP, Lappi SE, Seidler FJ. Prenatal terbutaline exposure in the rat: Selective effects on development of noradrenergic projections to cerebellum Brain Research Bulletin. 23: 263-265. PMID 2590837 DOI: 10.1016/0361-9230(89)90206-2 |
0.406 |
|
| 1988 |
Bell JM, Whitmore WL, Barnes G, Seidler FJ, Slotkin TA. Perinatal dietary exposure to soy lecithin: altered sensitivity to central cholinergic stimulation. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 4: 497-501. PMID 3455608 DOI: 10.1016/0736-5748(86)90001-8 |
0.433 |
|
| 1988 |
Navarro HA, Lachowicz J, Bartolome J, Whitmore WL, Slotkin TA. Effects of prenatal dexamethasone on development of ornithine decarboxylase activity in brain and peripheral tissues of rats. Pediatric Research. 24: 465-9. PMID 3174289 DOI: 10.1203/00006450-198810000-00009 |
0.334 |
|
| 1988 |
Slotkin TA. Perinatal exposure to methadone: How do early biochemical alterations cause neurofunctional disturbances? Progress in Brain Research. 73: 265-279. PMID 3047797 |
0.305 |
|
| 1988 |
Bell JM, Whitmore WL, Queen KL, Orband-Miller L, Slotkin TA. Biochemical determinants of growth sparing during neonatal nutritional deprivation or enhancement: ornithine decarboxylase, polyamines, and macromolecules in brain regions and heart. Pediatric Research. 22: 599-604. PMID 2446242 DOI: 10.1203/00006450-198711000-00024 |
0.311 |
|
| 1987 |
Slotkin TA, Cho H, Whitmore WL. Effects of prenatal nicotine exposure on neuronal development: Selective actions on central and peripheral catecholaminergic pathways Brain Research Bulletin. 18: 601-611. PMID 3607529 DOI: 10.1016/0361-9230(87)90130-4 |
0.419 |
|
| 1987 |
Slotkin TA, Orband-Miller L, Queen KL. Do catecholamines contribute to the effects of neonatal hypoxia on development of brain and heart? Influence of concurrent α-adrenergic blockade on ornithine decarboxylase activity International Journal of Developmental Neuroscience. 5: 135-143. PMID 2845716 DOI: 10.1016/0736-5748(87)90059-1 |
0.303 |
|
| 1986 |
Slotkin TA, Greer N, Faust J, Cho H, Seidler FJ. Effects of maternal nicotine injections on brain development in the rat: ornithine decarboxylase activity, nucleic acids and proteins in discrete brain regions. Brain Research Bulletin. 17: 41-50. PMID 3756543 DOI: 10.1016/0361-9230(86)90159-0 |
0.367 |
|
| 1986 |
Slotkin TA, Cowdery TS, Orband L, Pachman S, Whitmore WL. Effects of neonatal hypoxia on brain development in the rat: immediate and long-term biochemical alterations in discrete regions. Brain Research. 374: 63-74. PMID 3719331 DOI: 10.1016/0006-8993(86)90395-1 |
0.39 |
|
| 1986 |
Bell JM, Whitmore WL, Cowdery T, Slotkin TA. Perinatal dietary supplementation with a soy lecithin preparation: Effects on development of central catecholaminergic neurotransmitter systems Brain Research Bulletin. 17: 189-195. PMID 2876756 DOI: 10.1016/0361-9230(86)90115-2 |
0.424 |
|
| 1985 |
Slotkin TA, Pachman S, Kavlock RJ, Bartolome J. Early biochemical detection of adverse effects of a neurobehavioral teratogen: influence of prenatal methylmercury exposure on ornithine decarboxylase in brain and other tissues of fetal and neonatal rat. Teratology. 32: 195-202. PMID 4049277 DOI: 10.1002/tera.1420320207 |
0.39 |
|
| 1985 |
Morris G, Nadler JV, Nemeroff CB, Slotkin TA. Effects of neonatal treatment with 6-aminonicotinamide on basal and isoproterenol-stimulated ornithine decarboxylase activity in cerebellum of the development rat. Biochemical Pharmacology. 34: 3281-4. PMID 2931085 DOI: 10.1016/0006-2952(85)90346-6 |
0.411 |
|
| 1985 |
Seidler FJ, Slotkin TA. Adrenomedullary function in the neonatal rat: responses to acute hypoxia The Journal of Physiology. 358: 1-16. PMID 2858585 DOI: 10.1113/jphysiol.1985.sp015536 |
0.341 |
|
| 1985 |
Bell JM, Slotkin TA. Perinatal dietary supplementation with a commercial soy lecithin preparation: Effects on behavior and brain biochemistry in the developing rat Developmental Psychobiology. 18: 383-394. PMID 2415412 |
0.423 |
|
| 1985 |
Slotkin TA, Pachman S, Kavlock RJ, Bartolome J. Effects of neonatal methylmercury exposure on development of nucleic acids and proteins in rat brain: regional specificity. Brain Research Bulletin. 14: 397-400. PMID 2411358 DOI: 10.1016/0361-9230(85)90015-2 |
0.383 |
|
| 1984 |
Slotkin TA, Bartolome J, Persons D, Whitmore WL. Polyamines in brain and heart of the neonatal rat: effects of inhibitors of ornithine decarboxylase and spermidine synthase. Life Sciences. 35: 1125-31. PMID 6434889 DOI: 10.1016/0024-3205(84)90078-X |
0.339 |
|
| 1984 |
Slotkin TA, Persons D, Slepetis RJ, Taylor D, Bartolome J. Control of nucleic acid and protein synthesis in developing brain, kidney, and heart of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase. Teratology. 30: 211-24. PMID 6208628 DOI: 10.1002/tera.1420300209 |
0.319 |
|
| 1984 |
Bartolome J, Whitmore WL, Slotkin TA. Effects of neonatal mercuric chloride administration on growth and biochemical development of neuronal and non-neuronal tissues in the rat: Comparison with methylmercury Toxicology Letters. 22: 101-111. PMID 6147034 DOI: 10.1016/0378-4274(84)90052-3 |
0.361 |
|
| 1984 |
Bartolome J, Whitmore WL, Seidler FJ, Slotkin TA. Exposure to methylmercury in utero: effects on biochemical development of catecholamine neurotransmitter systems. Life Sciences. 35: 657-70. PMID 6146912 DOI: 10.1016/0024-3205(84)90261-3 |
0.429 |
|
| 1983 |
Slotkin TA, Seidler FJ, Whitmore WL, Weigel SJ, Slepetis RJ, Lerea L, Trepanier PA, Bartolome J. Critical periods for the role of ornithine decarboxylase and the polyamines in growth and development of the rat: Effects of exposure to α-difluoromethylornithine during discrete prenatal or postnatal intervals. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 1: 113-27. PMID 24875723 DOI: 10.1016/0736-5748(83)90038-2 |
0.389 |
|
| 1983 |
Slotkin TA, Whitmore WL, Lerea L, Slepetis RJ, Weigel SJ, Trepanier PA, Seidler FJ. Role of ornithine decarboxylase and the polyamines in nervous system development: Short-term postnatal administration of α-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 1: 7-16. PMID 24875600 DOI: 10.1016/0736-5748(83)90004-7 |
0.357 |
|
| 1983 |
Slotkin TA, Slepetis RJ, Weigel SJ, Whitmore WL. Effects of alpha-fluoromethylhistidine (FMH), an irreversible inhibitor of histidine decarboxylase, on development of brain histamine and catecholamine systems in the neonatal rat. Life Sciences. 32: 2897-903. PMID 6855476 DOI: 10.1016/0024-3205(83)90326-0 |
0.386 |
|
| 1983 |
Morris G, Lau C, Slotkin TA. Regulation of brain ornithine decarboxylase activity in the neonatal rat European Journal of Pharmacology. 88: 177-184. PMID 6852109 DOI: 10.1016/0014-2999(83)90004-3 |
0.358 |
|
| 1983 |
Morris G, Seidler FJ, Slotkin TA. Stimulation of ornithine decarboxylase by histamine or norepinephrine in brain regions of the developing rat: Evidence for biogenic amines as trophic agents in neonatal brain development Life Sciences. 32: 1565-1571. PMID 6835005 DOI: 10.1016/0024-3205(83)90862-7 |
0.378 |
|
| 1983 |
Slotkin TA, Bartolome J, Whitmore WL. Developmental effects of α-fluoromethylhistidine, an irreversible inhibitor of histidine decarboxylase, on growth and on levels and turnover of catecholamines Life Sciences. 33: 2137-2145. PMID 6645794 DOI: 10.1016/0024-3205(83)90338-7 |
0.313 |
|
| 1982 |
Bartolome J, Chait EA, Trepanier P, Whitmore WL, Weigel S, Slotkin TA. Organ specificity of neonatal methyl mercury hydroxide poisoning in the rat: effects of ornithine decarboxylase activity in developing tissues. Toxicology Letters. 13: 267-76. PMID 7147271 DOI: 10.1016/0378-4274(82)90222-3 |
0.337 |
|
| 1982 |
Slotkin TA, Weigel SJ, Whitmore WL, Seidler FJ. Maternal methadone administration: deficit in development of alpha-noradrenergic responses in developing rat brain as assessed by norepinephrine stimulation of 33Pi incorporation into phospholipids in vivo. Biochemical Pharmacology. 31: 1899-902. PMID 6285928 DOI: 10.1016/0006-2952(82)90494-4 |
0.408 |
|
| 1982 |
Smith P, Slotkin TA, Mills E. Development of sympathetic ganglionic neurotransmission in the neonatal rat. Pre- and postganglionic nerve response to asphyxia and 2-deoxyglucose Neuroscience. 7: 501-507. PMID 6281684 DOI: 10.1016/0306-4522(82)90283-4 |
0.34 |
|
| 1982 |
Chantry CJ, Seidler FJ, Slotkin TA. Non-neurogenic mechanism for reserpine-induced release of catecholamines from the adrenal medulla of neonatal rats: possible modulation by opiate receptors. Neuroscience. 7: 673-8. PMID 6280102 DOI: 10.1016/0306-4522(82)90073-2 |
0.335 |
|
| 1982 |
Lau C, Slotkin TA. Maturation of sympathetic neurotransmission in the rat heart. VIII. Slowed development of noradrenergic synapses resulting from hypothyroidism Journal of Pharmacology and Experimental Therapeutics. 220: 629-636. PMID 6278128 |
0.323 |
|
| 1982 |
Seidler FJ, Whitmore WL, Slotkin TA. Delays in growth and biochemical development of rat brain caused by maternal methadone administration: are the alterations in synaptogenesis and cellular maturation independent of reduced maternal food intake? Developmental Neuroscience. 5: 13-8. PMID 6125371 DOI: 10.1159/000112657 |
0.312 |
|
| 1981 |
Subramanian N, Whitmore WL, Slotkin TA. Trans-synaptic modulation of histamine H-1 receptor development in rat brain Journal of Neuroscience. 1: 674-678. PMID 7346575 |
0.368 |
|
| 1981 |
Slotkin TA, Weigel SJ, Barnes GA, Whitmore WL, Seidler FJ. Alterations in the development of catecholamine turnover induced by perinatal methadone: Differences in central vs. peripheral sympathetic nervous systems Life Sciences. 29: 2519-2525. PMID 7321774 DOI: 10.1016/0024-3205(81)90707-4 |
0.37 |
|
| 1981 |
Smith PG, Mills E, Slotkin TA. Maturation of sympathetic neurotransmission in the efferent pathway to the rat heart: Ultrastructural analysis of ganglionic synaptogenesis in euthyroid and hyperthyroid neonates Neuroscience. 6: 911-918. PMID 6264344 DOI: 10.1016/0306-4522(81)90172-X |
0.315 |
|
| 1979 |
Slotkin TA, Whitmore WL, Salvaggio M, Seidler FJ. Perinatal methadone addiction affects brain synaptic development of biogenic amine systems in the rat. Life Sciences. 24: 1223-9. PMID 571949 DOI: 10.1016/0024-3205(79)90059-6 |
0.306 |
|
| 1978 |
Kirksey DF, Seidler FJ, Slotkin TA. Ontogeny of (--)-[3H]norepinephrine uptake properties of synaptic storage vesicles of rat brain. Brain Research. 150: 367-75. PMID 678975 DOI: 10.1016/0006-8993(78)90287-1 |
0.333 |
|
| 1978 |
Slotkin TA, Seidler FJ, Whitmore WL. Methadone inhibits serotonin and norephinephrine uptake into rat brain synaptosomes and synaptic vesicles in vitro but not in vivo. European Journal of Pharmacology. 49: 357-62. PMID 668807 DOI: 10.1016/0014-2999(78)90309-6 |
0.301 |
|
| 1977 |
Bartolomé J, Bartolomé M, Seidler J, Anderson TR, Slotkin TA. Effects of early postnatal guanethidine administration on adrenal medulla and brain of developing rats. Biochemical Pharmacology. 25: 2387-90. PMID 999726 DOI: 10.1016/0006-2952(76)90033-2 |
0.371 |
|
| 1977 |
Thadani PV, Slotkin TA, Schanberg SM. Effects of late prenatal or early postnatal ethanol exposure on ornithine decarboxylase activity in brain and heart of developing rats. Neuropharmacology. 16: 289-93. PMID 859687 DOI: 10.1016/0028-3908(77)90109-5 |
0.3 |
|
| 1977 |
Thadani PV, Lau C, Slotkin TA, Schanberg SM. Effect of maternal ethanol ingestion on neonatal rat brain and heart ornithine decarboxylase. Biochemical Pharmacology. 26: 523-7. PMID 849350 DOI: 10.1016/0006-2952(77)90328-8 |
0.309 |
|
| 1977 |
Lau C, Bartolomé M, Slotkin TA. Development of central and peripheral catecholaminergic systems in rats addicted perinatally to methadone Neuropharmacology. 16: 473-478. PMID 21355 DOI: 10.1016/0028-3908(77)90003-X |
0.408 |
|
| 1977 |
ROSENTHAL RN, SLOTKIN TA. DEVELOPMENT OF NICOTINIC RESPONSES IN THE RAT ADRENAL MEDULLA AND LONG‐TERM EFFECTS OF NEONATAL NICOTINE ADMINISTRATION British Journal of Pharmacology. 60: 59-64. PMID 18246 DOI: 10.1111/j.1476-5381.1977.tb16747.x |
0.301 |
|
| 1977 |
Lau C, Bartolomé J, Seidler F, Slotkin T. Critical periods for effects of prenatal reserpine administration on development of rat brain and adrenal medulla Neuropharmacology. 16: 799-809. DOI: 10.1016/0028-3908(77)90141-1 |
0.37 |
|
| 1976 |
Bartolomé J, Slotkin TA. Effects of postnatal reserpine administration on sympatho-adrenal development in the rat Biochemical Pharmacology. 25: 1513-1519. PMID 942452 DOI: 10.1016/0006-2952(76)90070-8 |
0.316 |
|
| 1976 |
SEIDLER FJ, SLOTKIN TA. EFFECTS OF CHRONIC NICOTINE ADMINISTRATION ON THE DENERVATED RAT ADRENAL MEDULLA British Journal of Pharmacology. 56: 201-207. PMID 3249 DOI: 10.1111/j.1476-5381.1976.tb07443.x |
0.341 |
|
| 1975 |
SLOTKIN TA. EFFECTS OF RESERPINE ON THE ADRENAL MEDULLA OF THE SPONTANEOUSLY HYPERTENSIVE RAT British Journal of Pharmacology. 53: 349-356. PMID 1137729 DOI: 10.1111/j.1476-5381.1975.tb07370.x |
0.308 |
|
| 1975 |
Anderson TR, Slotkin TA. Maturation of the adrenal medulla-IV. Effects of morphine Biochemical Pharmacology. 24: 1469-1474. PMID 7 DOI: 10.1016/0006-2952(75)90020-9 |
0.339 |
|
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