Keith A. Crutcher - Publications

Affiliations: 
University of Cincinnati, Cincinnati, OH 
Area:
Neuroscience Biology

72/146 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Pettigrew DB, Singh N, Kirthivasan S, Crutcher KA. The Role of Tissue Geometry in Spinal Cord Regeneration. Medicina (Kaunas, Lithuania). 58. PMID 35454380 DOI: 10.3390/medicina58040542  0.716
2019 Pettigrew DB, Dobson CB, Isaacson LG, Leuthardt EC, Lilley HN, Suidan GL, Crutcher KA. Segregated neural explants exhibit co-oriented, asymmetric, neurite outgrowth. Plos One. 14: e0216263. PMID 31487284 DOI: 10.1371/Journal.Pone.0216263  0.728
2010 Richeri A, Bianchimano P, Crutcher KA, Brauer MM. Reduced sympathetic neurite outgrowth on uterine tissue sections from rats treated with estrogen. Cell and Tissue Research. 340: 287-301. PMID 20387079 DOI: 10.1007/S00441-010-0956-X  0.392
2008 Shelton SB, Pettigrew DB, Hermann AD, Zhou W, Sullivan PM, Crutcher KA, Strauss KI. A simple, efficient tool for assessment of mice after unilateral cortex injury. Journal of Neuroscience Methods. 168: 431-42. PMID 18164073 DOI: 10.1016/J.Jneumeth.2007.11.003  0.686
2007 Al-Shawi R, Hafner A, Chun S, Raza S, Crutcher K, Thrasivoulou C, Simons P, Cowen T. ProNGF, sortilin, and age-related neurodegeneration. Annals of the New York Academy of Sciences. 1119: 208-15. PMID 18056969 DOI: 10.1196/Annals.1404.024  0.41
2007 Pettigrew DB, Li YQ, Kuntz C, Crutcher KA. Global expression of NGF promotes sympathetic axonal growth in CNS white matter but does not alter its parallel orientation. Experimental Neurology. 203: 95-109. PMID 16989811 DOI: 10.1016/J.Expneurol.2006.07.026  0.759
2006 Zhou W, Scott SA, Shelton SB, Crutcher KA. Cathepsin D-mediated proteolysis of apolipoprotein E: possible role in Alzheimer's disease. Neuroscience. 143: 689-701. PMID 16997486 DOI: 10.1016/J.Neuroscience.2006.08.019  0.3
2006 Dhanoa NK, Krol KM, Jahed A, Crutcher KA, Kawaja MD. Null mutations for exon III and exon IV of the p75 neurotrophin receptor gene enhance sympathetic sprouting in response to elevated levels of nerve growth factor in transgenic mice. Experimental Neurology. 198: 416-26. PMID 16488412 DOI: 10.1016/J.Expneurol.2005.12.022  0.405
2005 Bierl MA, Jones EE, Crutcher KA, Isaacson LG. 'Mature' nerve growth factor is a minor species in most peripheral tissues. Neuroscience Letters. 380: 133-7. PMID 15854765 DOI: 10.1016/J.Neulet.2005.01.029  0.374
2004 Busciglio J, Brady S, Takashima A, Klein P, Kim L, LaFerla F, Geula C, Stokely M, Tezapsidis N, Gouras G, Strobel G, Crutcher K, Forero D. Axonal transport hypothesis moves on to implicate presenilin: Alzheimer research forum live discussion Journal of Alzheimer's Disease. 6: 537-545. PMID 15573458 DOI: 10.3233/Jad-2004-6511  0.337
2004 Marques MA, Owens PA, Crutcher KA. Progress toward identification of protease activity involved in proteolysis of apolipoprotein e in human brain. Journal of Molecular Neuroscience : Mn. 24: 73-80. PMID 15314253 DOI: 10.1385/Jmn:24:1:073  0.331
2003 Chalar C, Richeri A, Viettro L, Chávez-Genaro R, Bianchimano P, Marmol NM, Crutcher K, Burnstock G, Cowen T, Brauer MM. Plasticity in developing rat uterine sensory nerves: the role of NGF and TrkA. Cell and Tissue Research. 314: 191-205. PMID 13680358 DOI: 10.1007/S00441-003-0799-9  0.38
2003 Cowen T, Woodhoo A, Sullivan CD, Jolly R, Crutcher KA, Wyatt S, Michael GJ, Orike N, Gatzinsky K, Thrasivoulou C. Reduced age-related plasticity of neurotrophin receptor expression in selected sympathetic neurons of the rat. Aging Cell. 2: 59-69. PMID 12882335 DOI: 10.1046/J.1474-9728.2003.00035.X  0.356
2002 Kudwa AE, Shoemaker SE, Crutcher KA, Isaacson LG. Evidence for reduced accumulation of exogenous neurotrophin by aged sympathetic neurons. Brain Research. 948: 24-32. PMID 12383952 DOI: 10.1016/S0006-8993(02)02945-1  0.404
2002 Chávez-Genaro R, Crutcher K, Viettro L, Richeri A, Coirolo N, Burnstock G, Cowen T, Brauer MM. Differential effects of oestrogen on developing and mature uterine sympathetic nerves. Cell and Tissue Research. 308: 61-73. PMID 12012206 DOI: 10.1007/S00441-002-0521-3  0.368
2002 Crutcher KA. Aging and neuronal plasticity: lessons from a model. Autonomic Neuroscience : Basic & Clinical. 96: 25-32. PMID 11911499 DOI: 10.1016/S1566-0702(01)00373-3  0.382
2001 Pettigrew DB, Crutcher KA. Myelin contributes to the parallel orientation of axonal growth on white matter in vitro. Bmc Neuroscience. 2: 9. PMID 11399205 DOI: 10.1186/1471-2202-2-9  0.737
2001 Pettigrew DB, Shockley KP, Crutcher KA. Disruption of spinal cord white matter and sciatic nerve geometry inhibits axonal growth in vitro in the absence of glial scarring. Bmc Neuroscience. 2: 8. PMID 11399204 DOI: 10.1186/1471-2202-2-8  0.757
2000 Krol KM, Crutcher KA, Kalisch BE, Rylett RJ, Kawaja MD. Absence of p75(NTR) expression reduces nerve growth factor immunolocalization in cholinergic septal neurons. The Journal of Comparative Neurology. 427: 54-66. PMID 11042591 DOI: 10.1002/1096-9861(20001106)427:1<54::Aid-Cne4>3.0.Co;2-F  0.351
2000 Pettigrew DB, Levin L, Crutcher KA. Sympathetic neurite growth on central nervous system sections is region-specific and unaltered by aging. Neurobiology of Aging. 21: 629-38. PMID 11016531 DOI: 10.1016/S0197-4580(00)00155-X  0.723
2000 Shafer AJ, Crutcher KA, Isaacson LG. Remodeling of adult sensory axons in the superior cervical ganglion in response to exogenous nerve growth factor. Brain Research. 864: 252-62. PMID 10802032 DOI: 10.1016/S0006-8993(00)02163-6  0.432
1999 Kuchela GA, Crutcher KA, Naheed U, Thrasivoulou C, Cowen T. NGF expression in the aged rat pineal gland does not correlate with loss of sympathetic axonal branches and varicosities Neurobiology of Aging. 20: 685-693. PMID 10674435 DOI: 10.1016/S0197-4580(99)00064-0  0.442
1999 Pettigrew DB, Crutcher KA. White matter of the CNS supports or inhibits neurite outgrowth in vitro depending on geometry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8358-66. PMID 10493737 DOI: 10.1523/Jneurosci.19-19-08358.1999  0.752
1999 Walsh GS, Krol KM, Crutcher KA, Kawaja MD. Enhanced neurotrophin-induced axon growth in myelinated portions of the CNS in mice lacking the p75 neurotrophin receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4155-68. PMID 10234043 DOI: 10.1523/Jneurosci.19-10-04155.1999  0.455
1998 Isaacson LG, Crutcher KA. Uninjured aged sympathetic neurons sprout in response to exogenous NGF in vivo. Neurobiology of Aging. 19: 333-9. PMID 9733166 DOI: 10.1016/S0197-4580(98)00073-6  0.442
1998 Tolar M, Scott SA, Crutcher KA. Sympathetic neurite outgrowth is greater on plaque-poor vs. plaque-rich regions of Alzheimer's disease cryostat sections. Brain Research. 787: 49-58. PMID 9518548 DOI: 10.1016/S0006-8993(97)01455-8  0.353
1998 Joshi SN, Crutcher KA. Rat microglia exhibit increased density on Alzheimer's plaques in vitro. Experimental Neurology. 149: 42-50. PMID 9454613 DOI: 10.1006/Exnr.1997.6678  0.333
1997 Kawaja MD, Crutcher KA. Sympathetic axons invade the brains of mice overexpressing nerve growth factor. The Journal of Comparative Neurology. 383: 60-72. PMID 9184986 DOI: 10.1002/(Sici)1096-9861(19970623)383:1<60::Aid-Cne5>3.0.Co;2-J  0.468
1996 Marques MA, Tolar M, Harmony JA, Crutcher KA. A thrombin cleavage fragment of apolipoprotein E exhibits isoform-specific neurotoxicity. Neuroreport. 7: 2529-32. PMID 8981417 DOI: 10.1097/00001756-199611040-00025  0.303
1996 Cowen T, Gavazzi I, Weingartner J, Crutcher KA. Levels of NGF protein do not correlate with changes in innervation of the rat iris in old age Neuroreport. 7: 2216-2220. PMID 8930992 DOI: 10.1097/00001756-199609020-00032  0.369
1996 Fahnestock M, Scott SA, Jetté N, Weingartner JA, Crutcher KA. Nerve growth factor mRNA and protein levels measured in the same tissue from normal and Alzheimer's disease parietal cortex. Brain Research. Molecular Brain Research. 42: 175-8. PMID 8915599 DOI: 10.1016/S0169-328X(96)00193-3  0.325
1996 Tian X, Scott SA, Weingartner J, Crutcher KA. Enhanced sympathetic neurite outgrowth on rat hippocampal tissue sections following septal lesions. Brain Research. 725: 111-4. PMID 8828593 DOI: 10.1016/0006-8993(96)00285-5  0.354
1996 Isaacson LG, Schwenk KL, Billieu SC, Crutcher KA. Sympathetic response to intracranial NGF infusion in the absence of afferent input: axonal sprouting without neurotransmitter production. Experimental Neurology. 141: 57-66. PMID 8797668 DOI: 10.1006/exnr.1996.0139  0.363
1995 Isaacson LG, Ondris D, Crutcher KA. Plasticity of mature sensory cerebrovascular axons following intracranial infusion of nerve growth factor. The Journal of Comparative Neurology. 361: 451-60. PMID 8550892 DOI: 10.1002/Cne.903610309  0.452
1995 Isaacson LG, Crutcher KA. The duration of sprouted cerebrovascular axons following intracranial infusion of nerve growth factor. Experimental Neurology. 131: 174-9. PMID 7895818 DOI: 10.1016/0014-4886(95)90039-X  0.442
1995 Scott SA, Mufson EJ, Weingartner JA, Skau KA, Crutcher KA. Nerve growth factor in Alzheimer's disease: increased levels throughout the brain coupled with declines in nucleus basalis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 6213-21. PMID 7666203 DOI: 10.1523/Jneurosci.15-09-06213.1995  0.361
1995 Yu C, Crutcher KA. Nerve growth factor immunoreactivity and sympathetic sprouting in the rat hippocampal formation. Brain Research. 672: 55-67. PMID 7538420 DOI: 10.1016/0006-8993(94)01344-H  0.424
1994 Scott SA, Liang S, Weingartner JA, Crutcher KA. Increased NGF-like activity in young but not aged rat hippocampus after septal lesions. Neurobiology of Aging. 15: 337-46. PMID 7936058 DOI: 10.1016/0197-4580(94)90029-9  0.358
1994 Scott SA, Crutcher KA. Nerve growth factor and Alzheimer's disease. Reviews in the Neurosciences. 5: 179-211. PMID 7889213 DOI: 10.1515/Revneuro.1994.5.3.179  0.384
1993 Crutcher KA, Scott SA, Liang S, Everson WV, Weingartner J. Detection of NGF-like activity in human brain tissue: increased levels in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2540-50. PMID 8501520 DOI: 10.1523/Jneurosci.13-06-02540.1993  0.344
1993 Carpenter MK, Crutcher KA, Kater SB. An analysis of the effects of Alzheimer's plaques on living neurons. Neurobiology of Aging. 14: 207-15. PMID 7686640 DOI: 10.1016/0197-4580(93)90002-S  0.384
1992 Liang S, Crutcher KA. Neuronal migration on laminin in vitro. Brain Research. Developmental Brain Research. 66: 127-32. PMID 1600626 DOI: 10.1016/0165-3806(92)90148-P  0.318
1992 Isaacson LG, Saffran BN, Crutcher KA. Nerve growth factor-induced sprouting of mature, uninjured sympathetic axons. The Journal of Comparative Neurology. 326: 327-36. PMID 1469116 DOI: 10.1002/Cne.903260302  0.435
1991 Weil SM, Madison RD, Crutcher KA. Collagen nerve guide tubes in the rat septohippocampal pathway. Restorative Neurology and Neuroscience. 3: 167-75. PMID 21551634 DOI: 10.3233/Rnn-1991-3401  0.445
1991 Crutcher KA, Weingartner J. Hippocampal NGF levels are not reduced in the aged Fischer 344 rat. Neurobiology of Aging. 12: 449-54. PMID 1770979 DOI: 10.1016/0197-4580(91)90072-R  0.323
1991 Crutcher KA, Neaderhauser J, Schmidt P, Weingartner J. Neurite outgrowth on postmortem human brain cryostat sections: studies of non-Alzheimer's and Alzheimer's tissue. Experimental Neurology. 114: 228-36. PMID 1748196 DOI: 10.1016/0014-4886(91)90039-F  0.387
1990 Crutcher KA. Age-related decrease in sympathetic sprouting is primarily due to decreased target receptivity: implications for understanding brain aging. Neurobiology of Aging. 11: 175-83. PMID 2362650 DOI: 10.1016/0197-4580(90)90543-9  0.373
1990 Saffran BN, Crutcher KA. NGF-induced remodeling of mature uninjured axon collaterals. Brain Research. 525: 11-20. PMID 2245317 DOI: 10.1016/0006-8993(90)91315-8  0.442
1990 Isaacson LG, Saffran BN, Crutcher KA. Intracerebral NGF infusion induces hyperinnervation of cerebral blood vessels. Neurobiology of Aging. 11: 51-5. PMID 2183082 DOI: 10.1016/0197-4580(90)90062-5  0.46
1990 Crutcher KA. The regulation of axonal growth in the mature mammalian nervous system. Acta Neurobiologiae Experimentalis. 50: 115-24. PMID 2130633  0.357
1989 Crutcher KA. Tissue sections from the mature rat brain and spinal cord as substrates for neurite outgrowth in vitro: extensive growth on gray matter but little growth on white matter. Experimental Neurology. 104: 39-54. PMID 2924869 DOI: 10.1016/0014-4886(89)90007-1  0.445
1989 Crutcher KA, Privitera M. Axonal regeneration on mature human brain tissue sections in culture. Annals of Neurology. 26: 580-3. PMID 2817832 DOI: 10.1002/Ana.410260414  0.428
1989 Collins F, Crutcher KA. Sustained elevation in hippocampal NGF-like biological activity following medial septal lesions in the rat Brain Research. 490: 355-360. PMID 2765870 DOI: 10.1016/0006-8993(89)90254-0  0.34
1989 Saffran BN, Woo JE, Mobley WC, Crutcher KA. Intraventricular NGF infusion in the mature rat brain enhances sympathetic innervation of cerebrovascular targets but fails to elicit sympathetic ingrowth. Brain Research. 492: 245-54. PMID 2752299 DOI: 10.1016/0006-8993(89)90907-4  0.477
1988 Crutcher KA, Marfurt CF. Nonregenerative axonal growth within the mature mammalian brain: ultrastructural identification of sympathohippocampal sprouts. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 2289-302. PMID 3249226  0.34
1987 Crutcher KA. Sympathetic sprouting in the central nervous system: a model for studies of axonal growth in the mature mammalian brain. Brain Research. 434: 203-33. PMID 3555709 DOI: 10.1016/0165-0173(87)90013-0  0.37
1986 Crutcher KA, Collins F. Entorhinal lesions result in increased nerved growth factor-like growth-promoting activity in medium conditioned by hippocampal slices Brain Research. 399: 383-389. PMID 3828773 DOI: 10.1016/0006-8993(86)91533-7  0.363
1986 Crutcher KA. The role of growth factors in neuronal development and plasticity. Crc Critical Reviews in Clinical Neurobiology. 2: 297-333. PMID 3536312  0.306
1984 Gibby WA, Crutcher KA. Absence of sympathetic sprouting in the rat olfactory bulb after cholinergic denervation. Experimental Neurology. 84: 386-95. PMID 6714350 DOI: 10.1016/0014-4886(84)90235-8  0.33
1982 Crutcher KA. Histochemical studies of sympathetic sprouting: fluorescence morphology of noradrenergic axons. Brain Research Bulletin. 9: 501-8. PMID 7172037 DOI: 10.1016/0361-9230(82)90158-7  0.364
1982 Crutcher KA, Davis JN. Target regulation of sympathetic sprouting in the rat hippocampal formation. Experimental Neurology. 75: 347-59. PMID 7106218 DOI: 10.1016/0014-4886(82)90166-2  0.536
1981 Crutcher KA, Davis JN. Sympathohippocampal sprouting is directed by a target tropic factor. Brain Research. 204: 410-4. PMID 7459636 DOI: 10.1016/0006-8993(81)90599-0  0.497
1981 Crutcher KA, Madison R, Davis JN. A study of the rat septohippocampal pathway using anterograde transport of horseradish peroxidase. Neuroscience. 6: 1961-73. PMID 6272155 DOI: 10.1016/0306-4522(81)90036-1  0.493
1981 Madison R, Crutcher KA, Davis JN. Sympathohippocampal neurons are inside the blood--brain barrier. Brain Research. 213: 183-9. PMID 6165441 DOI: 10.1016/0006-8993(81)91259-2  0.493
1981 Crutcher KA, Brothers L, Davis JN. Sympathetic noradrenergic sprouting in response to central cholinergic denervation; a histochemical study of neuronal sprouting in the rat hippocampal formation. Brain Research. 210: 115-28. PMID 6164438 DOI: 10.1016/0006-8993(81)90889-1  0.548
1981 Crutcher KA, Davis JN. Sympathetic noradrenergic sprouting in response to central cholinergic denervation Trends in Neurosciences. 4: 70-72. DOI: 10.1016/0166-2236(81)90024-2  0.548
1980 Crutcher KA, Davis JN. Noradrenergic sprouting in response to cholinergic denervation: the sympathohabenular connection. Experimental Neurology. 70: 187-91. PMID 7418768 DOI: 10.1016/0014-4886(80)90017-5  0.518
1980 Giron LT, Crutcher KA, Davis JN. Lymph nodes--a possible site for sympathetic neuronal regulation of immune responses. Annals of Neurology. 8: 520-5. PMID 6254440 DOI: 10.1002/Ana.410080509  0.432
1980 Crutcher KA, Davis JN. Hippocampal alpha- and beta-adrenergic receptors: comparison of [3H]dihydroalprenolol and [3H]WB 4101 binding with noradrenergic innervation in the rat. Brain Research. 182: 107-17. PMID 6243229 DOI: 10.1016/0006-8993(80)90834-3  0.453
1979 Crutcher KA, Brothers L, Davis JN. Sprouting of sympathetic nerves in the absence of afferent input. Experimental Neurology. 66: 778-83. PMID 488252 DOI: 10.1016/0014-4886(79)90221-8  0.545
1979 Wagner HR, Crutcher KA, Davis JN. Chronic estrogen treatment decreases beta-adrenergic responses in rat cerebral cortex. Brain Research. 171: 147-51. PMID 223732 DOI: 10.1016/0006-8993(79)90741-8  0.436
1979 Felten DL, Crutcher KA. Neuronal‐vascular relationships in the raphe nuclei, locus coeruleus, and substantia nigra in primates American Journal of Anatomy. 155: 467-481. PMID 114041 DOI: 10.1002/Aja.1001550405  0.324
Low-probability matches (unlikely to be authored by this person)
2002 Teter B, Raber J, Nathan B, Crutcher KA. The presence of apoE4, not the absence of apoE3, contributes to AD pathology. Journal of Alzheimer's Disease : Jad. 4: 155-63. PMID 12226534 DOI: 10.3233/Jad-2002-4305  0.298
1987 Saffran BN, Crutcher KA. Putative gliotoxin, alpha-aminoadipic acid, fails to kill hippocampal astrocytes in vivo. Neuroscience Letters. 81: 215-20. PMID 3696468 DOI: 10.1016/0304-3940(87)91001-9  0.296
1982 Crutcher KA, Collins F. In vitro evidence for two distinct hippocampal growth factors: Basis of neuronal plasticity? Science. 217: 67-68. PMID 7089542  0.296
1984 Crutcher KA, Chandler JP. Association of basal lamina with peripheral axons elongating within the rat central nervous system. Brain Research. 308: 177-81. PMID 6478201 DOI: 10.1016/0006-8993(84)90933-8  0.296
2011 Hudson AP, Balin BJ, Crutcher K, Robinson S. New thinking on the etiology and pathogenesis of late-onset Alzheimer's disease. International Journal of Alzheimer's Disease. 2011: 848395. PMID 21941673 DOI: 10.4061/2011/848395  0.292
2000 Brauer MM, Shockley KP, Chávez R, Richeri A, Cowen T, Crutcher KA. The role of NGF in pregnancy-induced degeneration and regeneration of sympathetic nerves in the guinea pig uterus Journal of the Autonomic Nervous System. 79: 19-27. PMID 10683502 DOI: 10.1016/S0165-1838(99)00094-6  0.291
2010 Crutcher KA, Lilley HN, Anthony SR, Zhou W, Narayanaswami V. Full-length apolipoprotein E protects against the neurotoxicity of an apoE-related peptide. Brain Research. 1306: 106-15. PMID 19836363 DOI: 10.1016/J.Brainres.2009.10.021  0.286
2003 Marques MA, Crutcher KA. Apolipoprotein E-related neurotoxicity as a therapeutic target for Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 20: 327-37. PMID 14501016 DOI: 10.1385/Jmn:20:3:327  0.281
2010 De Courten-Myers GM, Bakkar RM, Luo G, Webb TA, Crutcher KA. Down's syndrome with alzheimer's disease-like pathology: What can it teach us about the amyloid cascade hypothesis? International Journal of Alzheimer's Disease. DOI: 10.4061/2010/175818  0.274
1999 Tolar M, Keller JN, Chan S, Mattson MP, Marques MA, Crutcher KA. Truncated Apolipoprotein E (ApoE) Causes Increased Intracellular Calcium and May Mediate ApoE Neurotoxicity The Journal of Neuroscience. 19: 7100-7110. DOI: 10.1523/Jneurosci.19-16-07100.1999  0.271
1994 Crutcher KA, Clay MA, Scott SA, Tian X, Tolar M, Harmony JA. Neurite degeneration elicited by apolipoprotein E peptides. Experimental Neurology. 130: 120-6. PMID 7821387 DOI: 10.1006/Exnr.1994.1191  0.266
2003 Qiu Z, Crutcher KA, Hyman BT, Rebeck GW. ApoE isoforms affect neuronal N-methyl-D-aspartate calcium responses and toxicity via receptor-mediated processes. Neuroscience. 122: 291-303. PMID 14614897 DOI: 10.1016/J.Neuroscience.2003.08.017  0.261
1978 Crutcher KA, Bingham WG. Descending monoaminergic pathways in the primate spinal cord American Journal of Anatomy. 153: 159-164. PMID 101068 DOI: 10.1002/aja.1001530110  0.26
2008 Zhou W, Xu D, Zhang Q, Peng X, Jia J, Crutcher K. P3-290: Meta-analysis of APOE4 and outcome of traumatic brain injury Alzheimer's & Dementia. 4: T607-T607. DOI: 10.1016/J.Jalz.2008.05.1858  0.258
2004 Crutcher KA. Apolipoprotein E is a prime suspect, not just an accomplice, in Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 23: 181-8. PMID 15181246 DOI: 10.1385/Jmn:23:3:181  0.256
2002 Bazin HG, Marques MA, Owens AP, Linhardt RJ, Crutcher KA. Inhibition of apolipoprotein E-related neurotoxicity by glycosaminoglycans and their oligosaccharides. Biochemistry. 41: 8203-11. PMID 12069613 DOI: 10.1021/Bi025817E  0.256
2008 Zhou W, Xu D, Peng X, Zhang Q, Jia J, Crutcher KA. Meta-analysis of APOE4 allele and outcome after traumatic brain injury. Journal of Neurotrauma. 25: 279-90. PMID 18373478 DOI: 10.1089/Neu.2007.0489  0.255
1985 Crutcher KA, Chandler JP. Evidence for sprouting specificity following medial septal lesions in the rat. The Journal of Comparative Neurology. 237: 116-26. PMID 4044889 DOI: 10.1002/cne.902370109  0.254
1985 Collins F, Crutcher KA. Neurotrophic activity in the adult rat hippocampal formation: Regional distribution and increase after septal lesion Journal of Neuroscience. 5: 2809-2814. PMID 4045554  0.243
1993 Crutcher KA. Tissue sections as culture substrates: overview and critique. Hippocampus. 3: 157-63. PMID 8287094 DOI: 10.1002/Hipo.1993.4500030719  0.238
1996 Crutcher K, Tolar M, Harmony J, Marques M. 623 Apolipoprotein E-Derived 22 kDa fragment neurotoxicity: A new pathophysiological mechanism in Alzheimer's disease Neurobiology of Aging. 17: S155. DOI: 10.1016/S0197-4580(96)80625-7  0.236
1993 Crutcher KA, Anderton BH, Barger SW, Ohm TG, Snow AD. Cellular and molecular pathology in Alzheimer's disease. Hippocampus. 3: 271-87. PMID 8287105 DOI: 10.1002/Hipo.1993.4500030730  0.227
2006 Dobson CB, Sales SD, Hoggard P, Wozniak MA, Crutcher KA. The receptor-binding region of human apolipoprotein E has direct anti-infective activity. The Journal of Infectious Diseases. 193: 442-50. PMID 16388493 DOI: 10.1086/499280  0.225
2005 Ashford JW, Crutcher KA, Robinson SR, Smith MA. Foreword: Challenging views of Alzheimer's disease – 2004 Journal of Alzheimer's Disease. 7: 233-233. DOI: 10.3233/Jad-2005-7305  0.223
2006 Crutcher KA, Gendelman HE, Kipnis J, Perez-Polo JR, Perry VH, Popovich PG, Weaver LC. Debate: "is increasing neuroinflammation beneficial for neural repair?". Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 195-211. PMID 18040798 DOI: 10.1007/S11481-006-9021-7  0.22
2002 Crutcher KA, Robinson SR, Smith MA. Challenging Views of Alzheimer's disease Journal of Alzheimer's Disease. 4: 129-130. DOI: 10.3233/Jad-2002-4301  0.218
1991 Crutcher KA. How to succeed in science. Perspectives in Biology and Medicine. 34: 213-8. PMID 2023797 DOI: 10.1353/Pbm.1991.0012  0.212
1993 Crutcher KA. Fetal tissue research: the cutting edge? The Linacre Quarterly. 60: 10-9. PMID 11651653 DOI: 10.1080/20508549.1993.11878198  0.212
2004 Crutcher KA, Robinson SR. Challenging views of Alzheimer's disease - Round II Neurobiology of Aging. 25: 561. DOI: 10.1016/J.Neurobiolaging.2003.12.018  0.212
2003 Goldstein L, Ashford JW, Busciglio J, Crutcher K, Gouras G, Kinoshita J, Mandelkow E, Sudol M. Live discussion. From here to there: AbetaPP as an axonal transport receptor--how could this explain neurodegeneration in AD. 15 July 2002. Journal of Alzheimer's Disease : Jad. 5: 483-9. PMID 14765517  0.205
1990 Crutcher KA. Current issues in neural regeneration research, edited by P. J. Reier, R. P. Bunge and F.J. Seil, New York, Alan R. Liss, Inc., 1988,410 pp. Synapse. 5: 165-165. DOI: 10.1002/Syn.890050212  0.196
1978 Crutcher KA, Humbertson AO. The organization of monoamine neurons within the brainstem of the north american opossum (didelphis virginiana) Journal of Comparative Neurology. 179: 195-221. PMID 8980724 DOI: 10.1002/cne.901790112  0.195
1985 Cook TM, Crutcher KA. Extensive target cell loss during development results in mossy fibers in the regio superior (CA1) of the rat hippocampal formation. Brain Research. 353: 19-30. PMID 4027681 DOI: 10.1016/0165-3806(85)90020-3  0.186
1993 Liang S, Crutcher KA. Movement of embryonic chick sympathetic neurons on laminin in vitro is preceded by neurite extension. Journal of Neuroscience Research. 36: 607-20. PMID 8145291 DOI: 10.1002/jnr.490360602  0.181
2004 Bishop G, Coleman P, Crutcher K, David D, Kinoshita J, LaFerla F, Leissring M, Shepherd J, Therianos S, Wang R, Wilson A, Zhu M. Live discussion: how the other half lives - or the what, how, and where, of the AbetaPP intracellular domain. Journal of Alzheimer's Disease : Jad. 6: 193-9. PMID 15171221 DOI: 10.3233/Jad-2004-6212  0.177
1990 Crutcher KA. Research on human embryos. Nature. 343: 10. PMID 2296281 DOI: 10.1038/343010A0  0.176
1983 Crutcher KA, Kesner RP, Novak JM. Medial septal lesions, radial arm maze performance, and sympathetic sprouting: a study of recovery of function. Brain Research. 262: 91-8. PMID 6831231 DOI: 10.1016/0006-8993(83)90472-9  0.168
1988 Cook TM, Crutcher KA. Lesion-induced CA1 mossy fibers in the rat represent a neoinnervation. Experimental Brain Research. 70: 433-6. PMID 2454840 DOI: 10.1007/BF00248368  0.165
1981 Crutcher KA. Cholinergic denervation of rat neocortex results in sympathetic innervation. Experimental Neurology. 74: 324-9. PMID 7286124 DOI: 10.1016/0014-4886(81)90172-2  0.164
1983 Chandler JP, Crutcher KA. The septohippocampal projection in the rat: an electron microscopic horseradish peroxidase study. Neuroscience. 10: 685-96. PMID 6316200 DOI: 10.1016/0306-4522(83)90210-5  0.163
1978 Crutcher KA, Humbertson AO, Martin GF. The origin of brainstem‐spinal pathways in the north american opossum (didelphis virginiana). Studies using the horseradish peroxidase method Journal of Comparative Neurology. 179: 169-193. PMID 8980723 DOI: 10.1002/cne.901790111  0.15
1986 Cook TM, Crutcher KA. Intrahippocampal injection of kainic acid produces significant pyramidal cell loss in neonatal rats. Neuroscience. 18: 79-92. PMID 3736859  0.148
1988 Crutcher KA, Danscher G, Geneser FA. Hippocampus and dentate area of the European hedgehog. Comparative histochemical study. Brain, Behavior and Evolution. 32: 269-76. PMID 3233486 DOI: 10.1159/000116555  0.148
1986 Kesner RP, Crutcher KA, Measom MO. Medial septal and nucleus basalis magnocellularis lesions produce order memory deficits in rats which mimic symptomatology of Alzheimer's disease. Neurobiology of Aging. 7: 287-95. PMID 3528890 DOI: 10.1016/0197-4580(86)90009-6  0.14
1988 Kesner RP, Crutcher K, Beers DR. Serial position curves for item (spatial location) information: role of the dorsal hippocampal formation and medial septum. Brain Research. 454: 219-26. PMID 3409005 DOI: 10.1016/0006-8993(88)90821-9  0.135
1989 Kesner RP, Adelstein TB, Crutcher KA. Equivalent spatial location memory deficits in rats with medial septum or hippocampal formation lesions and patients with dementia of the Alzheimer's type. Brain and Cognition. 9: 289-300. PMID 2923719 DOI: 10.1016/0278-2626(89)90038-9  0.134
1999 Tolar M, Keller JN, Chan S, Mattson MP, Marques MA, Crutcher KA. Truncated apolipoprotein E (ApoE) causes increased intracellular calcium and may mediate ApoE neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 7100-10. PMID 10436064  0.134
1987 Kesner RP, Adelstein T, Crutcher KA. Rats with nucleus basalis magnocellularis lesions mimic mnemonic symptomatology observed in patients with dementia of the Alzheimer's type. Behavioral Neuroscience. 101: 451-6. PMID 3651227 DOI: 10.1037/0735-7044.101.4.451  0.133
1997 Marques MA, Tolar M, Crutcher KA. Apolipoprotein E exhibits isoform-specific neurotoxicity Alzheimer's Research. 3: 1-6.  0.131
1982 Crutcher KA. Neonatal septal lesions result in sympathohippocampal innervation in the adult rat. Experimental Neurology. 76: 1-11. PMID 7084355 DOI: 10.1016/0014-4886(82)90096-6  0.126
2004 Zhou W, Crutcher KA. P2-305 Colocalization of apoE and cathepsin D in Alzheimer's disease brain Neurobiology of Aging. 25: S319. DOI: 10.1016/S0197-4580(04)81050-9  0.114
2004 Marques MA, Owens P, Suidan G, Crutcher KA. P2-300 Proteolysis of apoE in human brain homogenates may involve cathepsin D or related aspartic proteases Neurobiology of Aging. 25: S318. DOI: 10.1016/S0197-4580(04)81045-5  0.1
1978 Giron LT, Crutcher KA, Davis JN. Identification of sympathetic nerves and alpha-adrenergic receptors in lymph nodes Clinical Research. 26.  0.096
1997 Tolar M, Marques MA, Harmony JA, Crutcher KA. Neurotoxicity of the 22 kDa thrombin-cleavage fragment of apolipoprotein E and related synthetic peptides is receptor-mediated. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5678-86. PMID 9221767  0.094
1982 Valdes F, Dasheiff RM, Birmingham F, Crutcher KA, McNamara JO. Benzodiazepine receptor increases after repeated seizures: evidence for localization to dentate granule cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 193-7. PMID 6275387 DOI: 10.1073/Pnas.79.1.193  0.093
1990 Kesner RP, Crutcher KA, Omana H. Memory deficits following nucleus basalis magnocellularis lesions may be mediated through limbic, but not neocortical, targets. Neuroscience. 38: 93-102. PMID 2255401 DOI: 10.1016/0306-4522(90)90376-F  0.093
1987 Kesner RP, DiMattia BV, Crutcher KA. Evidence for neocortical involvement in reference memory. Behavioral and Neural Biology. 47: 40-53. PMID 3566691 DOI: 10.1016/S0163-1047(87)90145-2  0.089
1997 Gurwitz D, Marques MA, Tolar M, Harmony JAK, Crutcher KA. Neurotoxicity of apolipoprotein E thrombin cleavage fragments: Implications for Alzheimer's disease: Commentaries Neuroreport. 8: 1067-1068. PMID 9141094  0.088
2000 Crutcher KA. GTS-21 Taiho Pharmaceutical Co Ltd Current Opinion in Central and Peripheral Nervous System Investigational Drugs. 2: 478-484.  0.08
1981 Gospe SM, Cook LL, Crutcher KA, Wilson WA. Biochemical and histochemical studies of the effect of reserpine in Aplysia californica Comparative Biochemistry and Physiology. Part C, Comparative. 70: 273-276. DOI: 10.1016/0306-4492(81)90063-0  0.078
1982 Crutcher KA. Development of the rat septohippocampal projection: a retrograde fluorescent tracer study. Brain Research. 255: 145-50. PMID 6275957 DOI: 10.1016/0165-3806(82)90083-9  0.075
1995 Crutcher KA. The ethics of fetal tissue grafting should be considered along with the science Behavioral and Brain Sciences. 18: 53-54. DOI: 10.1017/s0140525x00037328  0.072
2005 Ashford JW, Crutcher KA, Robinson SR, Smith MA. Foreword: Challenging views of Alzheimer's disease - 2004 Journal of Alzheimer's Disease. 7: 233.  0.068
2003 Whitaker C, Eckman C, Almeida C, Feinstein D, Atwood C, Eckman E, Crutcher K, Hersh L, Leissring M, LaVoie M, Ertekin-Taner N, Shapiro P, Takahashi R, Yamin R, Mansourian S, et al. Live discussion: Amyloid-β degradation: The forgotten half of Alzheimer's disease Journal of Alzheimer's Disease. 5: 491-497. PMID 14765518  0.067
1992 Crutcher KA, Everson W. Fetal tissue. Nature. 357: 432. PMID 1608439 DOI: 10.1038/357432c0  0.065
1994 Basden BH, Basden DR, Coe WC, Decker S, Crutcher K. Retrieval inhibition in directed forgetting and posthypnotic amnesia. The International Journal of Clinical and Experimental Hypnosis. 42: 184-203. PMID 8063460 DOI: 10.1080/00207149408409351  0.058
1990 Crutcher KA. Letter: Fetal tissue research Scientist. 4.  0.051
2004 Zender PM, Crutcher KA. Visualizing Alzheimer's Disease research: A classroom collaboration of design and science Acm Siggraph 2004: Educators Program, Siggraph'04. 24. DOI: 10.1145/1186107.1186135  0.049
1977 Martin GF, Andrezik J, Crutcher K, Linauts M, Panneton M. The lateral reticular nucleus of the opossum (Didelphis virginiana). II. Connections. The Journal of Comparative Neurology. 174: 151-86. PMID 864033 DOI: 10.1002/cne.901740110  0.042
2009 Matykiewicz P, Duch W, Zender PM, Crutcher KA, Pestian JP. Neurocognitive approach to clustering of PubMed query results Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5507: 70-79. DOI: 10.1007/978-3-642-03040-6_9  0.025
1995 Crutcher KA. Religious scientists Scientist. 9.  0.024
1988 Crutcher KA. Fetal research ban. Science (New York, N.Y.). 242: 1227. PMID 3194762  0.017
1991 Crutcher KA. Government for the people, by the people does not obviate use of political litmus tests Scientist. 5.  0.011
1988 Crutcher KA. On science and religion Scientist. 2.  0.01
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