Feng-Shiun Shie, Ph.D. - Publications

Affiliations: 
2000 University of Washington, Seattle, Seattle, WA 
Area:
Neuroscience Biology, Nutrition, Pathology

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Tsay HJ, Gan YL, Su YH, Sun YY, Yao HH, Chen HW, Hsu YT, Hsu JT, Wang HD, Shie FS. Reducing brain Aβ burden ameliorates high-fat diet-induced fatty liver disease in APP/PS1 mice. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 173: 116404. PMID 38471275 DOI: 10.1016/j.biopha.2024.116404  0.378
2022 Huang YC, Hsu SM, Shie FS, Shiao YJ, Chao LJ, Chen HW, Yao HH, Chien MA, Lin CC, Tsay HJ. Reduced mitochondria membrane potential and lysosomal acidification are associated with decreased oligomeric Aβ degradation induced by hyperglycemia: A study of mixed glia cultures. Plos One. 17: e0260966. PMID 35073330 DOI: 10.1371/journal.pone.0260966  0.392
2022 Su IJ, Hsu CY, Shen S, Chao PK, Hsu JT, Hsueh JT, Liang JJ, Hsu YT, Shie FS. The Beneficial Effects of Combining Anti-Aβ Antibody NP106 and Curcumin Analog TML-6 on the Treatment of Alzheimer's Disease in APP/PS1 Mice. International Journal of Molecular Sciences. 23. PMID 35008983 DOI: 10.3390/ijms23010556  0.385
2021 Lai RH, Hsu YY, Shie FS, Huang CC, Chen MH, Juang JL. Non-genomic rewiring of vitamin D receptor to p53 as a key to Alzheimer's disease. Aging Cell. e13509. PMID 34725922 DOI: 10.1111/acel.13509  0.304
2021 Hsu JT, Tien CF, Yu GY, Shen S, Lee YH, Hsu PC, Wang Y, Chao PK, Tsay HJ, Shie FS. The Effects of Aβ Binding to the SARS-CoV-2 Spike Protein S1 Subunit and Angiotensin-Converting Enzyme 2. International Journal of Molecular Sciences. 22. PMID 34360989 DOI: 10.3390/ijms22158226  0.375
2019 Yeh SH, Shie FS, Liu HK, Yao HH, Kao PC, Lee YH, Chen LM, Hsu SM, Chao LJ, Wu KW, Shiao YJ, Tsay HJ. A high-sucrose diet aggravates Alzheimer's disease pathology, attenuates hypothalamic leptin signaling, and impairs food-anticipatory activity in APPswe/PS1dE9 mice. Neurobiology of Aging. PMID 31879131 DOI: 10.1016/j.neurobiolaging.2019.11.018  0.494
2018 Lee YH, Hsu HC, Kao PC, Shiao YJ, Yeh SH, Shie FS, Hsu SM, Yeh CW, Liu HK, Yang SB, Tsay HJ. Augmented Insulin and Leptin Resistance of High Fat Diet-Fed APPswe/PS1dE9 Transgenic Mice Exacerbate Obesity and Glycemic Dysregulation. International Journal of Molecular Sciences. 19. PMID 30096853 DOI: 10.3390/Ijms19082333  0.417
2015 Yeh CW, Yeh SH, Shie FS, Lai WS, Liu HK, Tzeng TT, Tsay HJ, Shiao YJ. Impaired cognition and cerebral glucose regulation are associated with astrocyte activation in the parenchyma of metabolically stressed APPswe/PS1dE9 mice. Neurobiology of Aging. PMID 26264859 DOI: 10.1016/J.Neurobiolaging.2015.07.022  0.376
2015 Shie FS, Shiao YJ, Yeh CW, Lin CH, Tzeng TT, Hsu HC, Huang FL, Tsay HJ, Liu HK. Obesity and Hepatic Steatosis Are Associated with Elevated Serum Amyloid Beta in Metabolically Stressed APPswe/PS1dE9 Mice. Plos One. 10: e0134531. PMID 26244977 DOI: 10.1371/journal.pone.0134531  0.435
2011 Yang CN, Shiao YJ, Shie FS, Guo BS, Chen PH, Cho CY, Chen YJ, Huang FL, Tsay HJ. Mechanism mediating oligomeric Aβ clearance by naïve primary microglia. Neurobiology of Disease. 42: 221-30. PMID 21220023 DOI: 10.1016/j.nbd.2011.01.005  0.319
2010 Chern JH, Hsu PC, Wang LW, Tsay HJ, Kang IJ, Shie FS. Modulation of microglial immune responses by a novel thiourea derivative. Chemico-Biological Interactions. 188: 228-36. PMID 20637185 DOI: 10.1016/j.cbi.2010.07.006  0.361
2010 Huang WC, Yen FC, Shie FS, Pan CM, Shiao YJ, Yang CN, Huang FL, Sung YJ, Tsay HJ. TGF-beta1 blockade of microglial chemotaxis toward Abeta aggregates involves SMAD signaling and down-regulation of CCL5. Journal of Neuroinflammation. 7: 28. PMID 20429874 DOI: 10.1186/1742-2094-7-28  0.372
2009 Huang WC, Yen FC, Shiao YJ, Shie FS, Chan JL, Yang CN, Sung YJ, Huang FL, Tsay HJ. Enlargement of Abeta aggregates through chemokine-dependent microglial clustering. Neuroscience Research. 63: 280-7. PMID 19367788 DOI: 10.1016/j.neures.2009.01.001  0.454
2009 Shie FS, Nivison M, Hsu PC, Montine TJ. Modulation of microglial innate immunity in Alzheimer's disease by activation of peroxisome proliferator-activated receptor gamma. Current Medicinal Chemistry. 16: 643-51. PMID 19199928 DOI: 10.2174/092986709787458399  0.307
2007 Shie FS, Woltjer RL. Manipulation of microglial activation as a therapeutic strategy in Alzheimer's disease. Current Medicinal Chemistry. 14: 2865-71. PMID 18045132 DOI: 10.2174/092986707782359981  0.439
2005 Shie FS, Montine KS, Breyer RM, Montine TJ. Microglial EP2 as a new target to increase amyloid beta phagocytosis and decrease amyloid beta-induced damage to neurons. Brain Pathology (Zurich, Switzerland). 15: 134-8. PMID 15912885 DOI: 10.1111/J.1750-3639.2005.Tb00509.X  0.429
2005 Shie FS, Breyer RM, Montine TJ. Microglia lacking E Prostanoid Receptor subtype 2 have enhanced Abeta phagocytosis yet lack Abeta-activated neurotoxicity. The American Journal of Pathology. 166: 1163-72. PMID 15793296 DOI: 10.1016/S0002-9440(10)62336-X  0.446
2003 Shie FS, LeBoeuf RC, Jin LW, LeBoeur RC. Early intraneuronal Abeta deposition in the hippocampus of APP transgenic mice. Neuroreport. 14: 123-9. PMID 12544843 DOI: 10.1097/01.wnr.0000051151.87269.7d  0.553
2003 Brich J, Shie FS, Howell BW, Li R, Tus K, Wakeland EK, Jin LW, Mumby M, Churchill G, Herz J, Cooper JA. Genetic modulation of tau phosphorylation in the mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 187-92. PMID 12514215  0.338
2003 Brich J, Shie F, Howell BW, Li R, Tus K, Wakeland EK, Jin L, Mumby M, Churchill G, Herz J, Cooper JA. Genetic Modulation of Tau Phosphorylation in the Mouse The Journal of Neuroscience. 23: 187-192. DOI: 10.1523/Jneurosci.23-01-00187.2003  0.338
2002 Jin LW, Hua DH, Shie FS, Maezawa I, Sopher B, Martin GM. Novel tricyclic pyrone compounds prevent intracellular APP C99-induced cell death. Journal of Molecular Neuroscience : Mn. 19: 57-61. PMID 12212794 DOI: 10.1007/S12031-002-0011-9  0.416
2002 Shie FS, Jin LW, Cook DG, Leverenz JB, LeBoeuf RC. Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice. Neuroreport. 13: 455-9. PMID 11930160 DOI: 10.1097/00001756-200203250-00019  0.53
2000 Shie F, Jin L, Leverenz J, LeBoeuf R. Early β-amyloid deposition in hippocampal neurons in β-amyloid precursor protein 695 (APP695) transgenic mice Neurobiology of Aging. 21: 225. DOI: 10.1016/S0197-4580(00)83346-1  0.5
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