C Garrison Fathman - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Immunology, Neuroscience Biology, Molecular Biology

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Slight-Webb S, Lu R, Ritterhouse LL, Munroe ME, Maecker HT, Fathman CG, Utz PJ, Merrill JT, Guthridge JM, James JA. Autoantibody-Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity. Arthritis & Rheumatology (Hoboken, N.J.). PMID 27059145 DOI: 10.1002/art.39706  0.32
2015 Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. Pillars article: A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 2000. 100: 655-669. Journal of Immunology (Baltimore, Md. : 1950). 194: 2961-75. PMID 25795787  0.48
2012 Junttila IS, Creusot RJ, Moraga I, Bates DL, Wong MT, Alonso MN, Suhoski MM, Lupardus P, Meier-Schellersheim M, Engleman EG, Utz PJ, Fathman CG, Paul WE, Garcia KC. Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines. Nature Chemical Biology. 8: 990-8. PMID 23103943 DOI: 10.1038/nchembio.1096  0.32
2012 Maecker HT, Lindstrom TM, Robinson WH, Utz PJ, Hale M, Boyd SD, Shen-Orr SS, Fathman CG. New tools for classification and monitoring of autoimmune diseases. Nature Reviews. Rheumatology. 8: 317-28. PMID 22647780 DOI: 10.1038/nrrheum.2012.66  0.32
2012 Levin AM, Bates DL, Ring AM, Krieg C, Lin JT, Su L, Moraga I, Raeber ME, Bowman GR, Novick P, Pande VS, Fathman CG, Boyman O, Garcia KC. Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'. Nature. 484: 529-33. PMID 22446627 DOI: 10.1038/nature10975  0.36
2012 Rothbard JB, Kurnellas MP, Brownell S, Adams CM, Su L, Axtell RC, Chen R, Fathman CG, Robinson WH, Steinman L. Therapeutic effects of systemic administration of chaperone αB-crystallin associated with binding proinflammatory plasma proteins. The Journal of Biological Chemistry. 287: 9708-21. PMID 22308023 DOI: 10.1074/jbc.M111.337691  0.36
2012 Lin JT, Stein EA, Wong MT, Kalpathy KJ, Su LL, Utz PJ, Robinson WH, Fathman CG. Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis. Clinical Immunology (Orlando, Fla.). 142: 127-38. PMID 22075384 DOI: 10.1016/j.clim.2011.09.008  0.32
2011 Whiting CC, Su LL, Lin JT, Fathman CG. GRAIL: a unique mediator of CD4 T-lymphocyte unresponsiveness. The Febs Journal. 278: 47-58. PMID 21078124 DOI: 10.1111/j.1742-4658.2010.07922.x  0.32
2009 Yip L, Su L, Sheng D, Chang P, Atkinson M, Czesak M, Albert PR, Collier AR, Turley SJ, Fathman CG, Creusot RJ. Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes. Nature Immunology. 10: 1026-33. PMID 19668219 DOI: 10.1038/ni.1773  0.36
2009 Su LL, Iwai H, Lin JT, Fathman CG. The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 438-44. PMID 19542455 DOI: 10.4049/jimmunol.0900204  0.32
2009 Lin JT, Lineberry NB, Kattah MG, Su LL, Utz PJ, Fathman CG, Wu L. Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression. Journal of Immunology (Baltimore, Md. : 1950). 182: 5919-28. PMID 19414743 DOI: 10.4049/jimmunol.0803986  1
2008 Kodama K, Butte AJ, Creusot RJ, Su L, Sheng D, Hartnett M, Iwai H, Soares LR, Fathman CG. Tissue- and age-specific changes in gene expression during disease induction and progression in NOD mice. Clinical Immunology (Orlando, Fla.). 129: 195-201. PMID 18801706 DOI: 10.1016/j.clim.2008.07.028  0.36
2008 Lineberry N, Su L, Soares L, Fathman CG. The single subunit transmembrane E3 ligase gene related to anergy in lymphocytes (GRAIL) captures and then ubiquitinates transmembrane proteins across the cell membrane. The Journal of Biological Chemistry. 283: 28497-505. PMID 18713730 DOI: 10.1074/jbc.M805092200  1
2008 Lineberry NB, Su LL, Lin JT, Coffey GP, Seroogy CM, Fathman CG. Cutting edge: The transmembrane E3 ligase GRAIL ubiquitinates the costimulatory molecule CD40 ligand during the induction of T cell anergy. Journal of Immunology (Baltimore, Md. : 1950). 181: 1622-6. PMID 18641297  1
2007 Fathman CG, Lineberry NB. Molecular mechanisms of CD4+ T-cell anergy. Nature Reviews. Immunology. 7: 599-609. PMID 17612584 DOI: 10.1038/nri2131  1
2007 Schartner JM, Fathman CG, Seroogy CM. Preservation of self: an overview of E3 ubiquitin ligases and T cell tolerance. Seminars in Immunology. 19: 188-96. PMID 17403607 DOI: 10.1016/j.smim.2007.02.010  0.48
2007 MacKenzie DA, Schartner J, Lin J, Timmel A, Jennens-Clough M, Fathman CG, Seroogy CM. GRAIL is up-regulated in CD4+ CD25+ T regulatory cells and is sufficient for conversion of T cells to a regulatory phenotype. The Journal of Biological Chemistry. 282: 9696-702. PMID 17259178 DOI: 10.1074/jbc.M604192200  0.48
2006 Su L, Lineberry N, Huh Y, Soares L, Fathman CG. A novel E3 ubiquitin ligase substrate screen identifies Rho guanine dissociation inhibitor as a substrate of gene related to anergy in lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 177: 7559-66. PMID 17114425  1
2006 Lineberry N, Fathman CG. T cell anergy: where it's LAT. Immunity. 24: 501-3. PMID 16713965 DOI: 10.1016/j.immuni.2006.05.002  1
2006 Lineberry N, Fathman CG. CYLD: deubiquitination-induced TCR signaling. Nature Immunology. 7: 369-70. PMID 16550202 DOI: 10.1038/ni0406-369  1
2006 Lineberry N, Fathman CG. T Cell Anergy: Where It's LAT (DOI:10.1016/j.immuni.2006.05.002) Immunity. 25: 175. DOI: 10.1016/j.immuni.2006.07.008  1
2005 Fathman CG, Soares L, Chan SM, Utz PJ. An array of possibilities for the study of autoimmunity. Nature. 435: 605-11. PMID 15931213 DOI: 10.1038/nature03726  0.36
2004 Chan SM, Ermann J, Su L, Fathman CG, Utz PJ. Protein microarrays for multiplex analysis of signal transduction pathways. Nature Medicine. 10: 1390-6. PMID 15558056 DOI: 10.1038/nm1139  0.36
2004 Su L, Creusot RJ, Gallo EM, Chan SM, Utz PJ, Fathman CG, Ermann J. Murine CD4+CD25+ regulatory T cells fail to undergo chromatin remodeling across the proximal promoter region of the IL-2 gene. Journal of Immunology (Baltimore, Md. : 1950). 173: 4994-5001. PMID 15470042  0.36
2004 Jeon MS, Atfield A, Venuprasad K, Krawczyk C, Sarao R, Elly C, Yang C, Arya S, Bachmaier K, Su L, Bouchard D, Jones R, Gronski M, Ohashi P, Wada T, ... ... Fathman CG, et al. Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction Immunity. 21: 167-177. PMID 15308098 DOI: 10.1016/j.immuni.2004.07.013  0.36
2004 Seroogy CM, Soares L, Ranheim EA, Su L, Holness C, Bloom D, Fathman CG. The gene related to anergy in lymphocytes, an E3 ubiquitin ligase, is necessary for anergy induction in CD4 T cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 79-85. PMID 15210761  0.48
2004 Soares L, Seroogy C, Skrenta H, Anandasabapathy N, Lovelace P, Chung CD, Engleman E, Fathman CG. Two isoforms of otubain 1 regulate T cell anergy via GRAIL. Nature Immunology. 5: 45-54. PMID 14661020 DOI: 10.1038/ni1017  0.36
2003 Seroogy CM, Fathman CG. T-cell anergy: from phenotype to genotype and back. Immunologic Research. 28: 255-64. PMID 14713718 DOI: 10.1385/IR:28:3:255  0.48
2003 Ermann J, Chung CD, Fathman CG. Scratching the (T cell) surface. Genome Biology. 5: 202. PMID 14709166 DOI: 10.1186/gb-2003-5-1-202  0.36
2003 Anandasabapathy N, Ford GS, Bloom D, Holness C, Paragas V, Seroogy C, Skrenta H, Hollenhorst M, Fathman CG, Soares L. GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells. Immunity. 18: 535-47. PMID 12705856 DOI: 10.1016/S1074-7613(03)00084-0  0.36
2002 Tarner IH, Nakajima A, Seroogy CM, Ermann J, Levicnik A, Contag CH, Fathman CG. Retroviral gene therapy of collagen-induced arthritis by local delivery of IL-4. Clinical Immunology (Orlando, Fla.). 105: 304-14. PMID 12498812 DOI: 10.1006/clim.2002.5299  0.48
2002 Oh JW, Seroogy CM, Meyer EH, Akbari O, Berry G, Fathman CG, Dekruyff RH, Umetsu DT. CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation. The Journal of Allergy and Clinical Immunology. 110: 460-8. PMID 12209095  0.48
2001 Costa GL, Sandora MR, Nakajima A, Nguyen EV, Taylor-Edwards C, Slavin AJ, Contag CH, Fathman CG, Benson JM. Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunit. Journal of Immunology (Baltimore, Md. : 1950). 167: 2379-87. PMID 11490028  0.48
2001 Nakajima A, Seroogy CM, Sandora MR, Tarner IH, Costa GL, Taylor-Edwards C, Bachmann MH, Contag CH, Fathman CG. Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis. The Journal of Clinical Investigation. 107: 1293-301. PMID 11375419 DOI: 10.1172/JCI12037  0.48
2000 Fathman CG, Seroogy CM. Application of gene therapy in autoimmune disease. Current Directions in Autoimmunity. 2: 189-202. PMID 11791456  0.48
2000 Fassò M, Anandasabapathy N, Crawford F, Kappler J, Fathman CG, Ridgway WM. T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo. The Journal of Experimental Medicine. 192: 1719-30. PMID 11120769 DOI: 10.1084/jem.192.12.1719  0.36
2000 Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 100: 655-69. PMID 10761931  0.48
2000 Fathman CG, Costa GL, Seroogy CM. Gene therapy for autoimmune disease. Clinical Immunology (Orlando, Fla.). 95: S39-43. PMID 10729236 DOI: 10.1006/clim.1999.4812  0.48
2000 Costa GL, Benson JM, Seroogy CM, Achacoso P, Fathman CG, Nolan GP. Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 164: 3581-90. PMID 10725713  0.48
2000 Skrenta H, Yang Y, Pestka S, Fathman CG. Ligand-independent down-regulation of IFN-gamma receptor 1 following TCR engagement. Journal of Immunology (Baltimore, Md. : 1950). 164: 3506-11. PMID 10725704  0.36
2000 Seroogy CM, Fathman CG. The application of gene therapy in autoimmune diseases. Gene Therapy. 7: 9-13. PMID 10680009 DOI: 10.1038/sj.gt.3301111  0.48
1998 Dal Canto RA, Costa G, Shaw MD, Seroogy C, Nolan GP, Fathman CG. Local delivery of cytokines by retrovirally transduced antigen-specific TCR+ hybridoma cells in experimental autoimmune encephalomyelitis. European Cytokine Network. 9: 83-91. PMID 9831193  0.36
1998 Seroogy CM, Fathman CG. A gene therapy approach to treatment of autoimmune disease. Immunologic Research. 18: 15-26. PMID 9724846 DOI: 10.1007/BF02786510  0.48
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