| Year |
Citation |
Score |
| 2023 |
Borgini M, Wieteska Ł, Hinck CS, Krzysiak T, Hinck AP, Wipf P. Synthesis of C-methyl-labeled amino acids and their incorporation into proteins in mammalian cells. Organic & Biomolecular Chemistry. 21: 9216-9229. PMID 37964666 DOI: 10.1039/d3ob01320k |
0.781 |
|
| 2023 |
LaPorte MG, Alverez C, Chatterley A, Kovaliov M, Carder EJ, Houghton MJ, Lim C, Miller ER, Samankumara LP, Liang M, Kerrigan K, Yue Z, Li S, Tomaino F, Wang F, ... ... Wipf P, et al. Optimization of 1,2,4-Triazole-Based p97 Inhibitors for the Treatment of Cancer. Acs Medicinal Chemistry Letters. 14: 977-985. PMID 37465292 DOI: 10.1021/acsmedchemlett.3c00163 |
0.55 |
|
| 2023 |
Borgini M, Wipf P. Synthesis of Veliparib Prodrugs and Determination of Drug-Release-Dependent PARP-1 Inhibition. Acs Medicinal Chemistry Letters. 14: 652-657. PMID 37197461 DOI: 10.1021/acsmedchemlett.3c00065 |
0.783 |
|
| 2023 |
Lazo JS, Isbell KN, Vasa SA, Llaneza DC, Rastelli EJ, Wipf P, Sharlow ER. Disruption of ovarian cancer STAT3 and p38 signaling with a small molecule inhibitor of PTP4A3 phosphatase. The Journal of Pharmacology and Experimental Therapeutics. PMID 36627205 DOI: 10.1124/jpet.122.001401 |
0.742 |
|
| 2022 |
Charaschanya M, Maskrey TS, LaPorte MG, Janjic JM, Wipf P. Synthesis and Optimization of Nitroxide-Based Inhibitors of Ferroptotic Cell Death in Cancer Cells and Macrophages. Acs Medicinal Chemistry Letters. 13: 403-408. PMID 35300093 DOI: 10.1021/acsmedchemlett.1c00561 |
0.719 |
|
| 2021 |
Lazo JS, Sharlow ER, Cornelison R, Hart DJ, Llaneza DC, Mendelson AJ, Rastelli EJ, Tasker NR, Landen CN, Wipf P. Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer. Biomolecules. 11. PMID 34209460 DOI: 10.3390/biom11070969 |
0.759 |
|
| 2021 |
Rastelli EJ, Sannino S, Hart DJ, Sharlow ER, Lazo JS, Brodsky JL, Wipf P. Synthesis and evaluation of bifunctional PTP4A3 phosphatase inhibitors activating the ER stress pathway. Bioorganic & Medicinal Chemistry Letters. 46: 128167. PMID 34089839 DOI: 10.1016/j.bmcl.2021.128167 |
0.755 |
|
| 2021 |
Borgini M, Mondal P, Liu R, Wipf P. Chemical modulation of Kv7 potassium channels. Rsc Medicinal Chemistry. 12: 483-537. PMID 34046626 DOI: 10.1039/d0md00328j |
0.773 |
|
| 2020 |
Mlakar L, Lane J, Takihara T, Lim C, Sprachman MM, Lloyd KR, Wipf P, Feghali-Bostwick C. Oxetanyl Sulfoxide MMS-350 Ameliorates Pulmonary Fibrosis , , and . Acs Medicinal Chemistry Letters. 11: 2312-2317. PMID 33214846 DOI: 10.1021/Acsmedchemlett.0C00433 |
0.721 |
|
| 2020 |
Czub MP, Boulton AM, Rastelli EJ, Tasker NR, Maskrey TS, Blanco IK, McQueeney KE, Bushweller JH, Minor W, Wipf P, Sharlow ER, Lazo JS. Structure of the complex of an iminopyridinedione PTP4A3 phosphatase inhibitor with human serum albumin. Molecular Pharmacology. PMID 32978326 DOI: 10.1124/molpharm.120.000131 |
0.745 |
|
| 2020 |
Terrab L, Rosenker CJ, Johnstone L, Ngo LK, Zhang L, Ware NF, Miller B, Topacio AZ, Sannino S, Brodsky JL, Wipf P. Synthesis and Selective Functionalization of Thiadiazine 1,1-Dioxides with Efficacy in a Model of Huntington's Disease. Acs Medicinal Chemistry Letters. 11: 984-990. PMID 32435415 DOI: 10.1021/Acsmedchemlett.0C00018 |
0.797 |
|
| 2020 |
Osano M, Jhaveri DP, Wipf P. Formation of 6-Azaindoles by Intramolecular Diels-Alder Reaction of Oxazoles and Total Synthesis of Marinoquinoline A. Organic Letters. PMID 32105087 DOI: 10.1021/Acs.Orglett.0C00417 |
0.374 |
|
| 2020 |
Nikolić AM, Živković F, Selaković Ž, Wipf P, Opsenica IM. One‐Pot Two‐Step Synthesis of Isochromene‐Fused CF3‐Substituted Pyrazoles European Journal of Organic Chemistry. DOI: 10.1002/Ejoc.202000942 |
0.356 |
|
| 2019 |
Tai S, Maskrey TS, Nyalapatla PR, Wipf P. Co(II)-salen catalyzed stereoselective cyclopropanation of fluorinated styrenes. Chirality. PMID 31680333 DOI: 10.1002/Chir.23144 |
0.335 |
|
| 2019 |
Lazo JS, Blanco IK, Tasker NR, Rastelli EJ, Burnett JC, Garrott SR, Hart DJ, McCloud RL, Hsu KL, Wipf P, Sharlow ER. Next-Generation Cell-active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase. The Journal of Pharmacology and Experimental Therapeutics. PMID 31601683 DOI: 10.1124/Jpet.119.262188 |
0.776 |
|
| 2019 |
Peyser BD, Hermone A, Salamoun JM, Burnett JC, Hollingshead MG, McGrath CF, Gussio R, Wipf P. Specific RITA modification produces hyperselective cytotoxicity while maintaining in vivo antitumor efficacy. Molecular Cancer Therapeutics. PMID 31341033 DOI: 10.1158/1535-7163.Mct-19-0185 |
0.329 |
|
| 2019 |
Tasker NR, Rastelli EJ, Burnett JC, Sharlow ER, Lazo JS, Wipf P. Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 31307888 DOI: 10.1016/J.Bmcl.2019.06.048 |
0.767 |
|
| 2019 |
Cao L, Wang C, Wipf P. Grob-Type Fragmentation Releases Paracyclophane Ring Strain in a Late-Stage Precursor of Haouamine A. Organic Letters. PMID 30779589 DOI: 10.1021/Acs.Orglett.9B00424 |
0.696 |
|
| 2019 |
Tasker NR, Rastelli EJ, Blanco IK, Burnett JC, Sharlow ER, Lazo JS, Wipf P. In-flow photooxygenation of aminothienopyridinones generates iminopyridinedione PTP4A3 phosphatase inhibitors. Organic & Biomolecular Chemistry. PMID 30746541 DOI: 10.1039/C9Ob00025A |
0.767 |
|
| 2018 |
LaPorte MG, Burnett JC, Colombo R, Bulfer SL, Alverez C, Chou TF, Neitz RJ, Green N, Moore WJ, Yue Z, Li S, Arkin MR, Wipf P, Huryn DM. Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97. Acs Medicinal Chemistry Letters. 9: 1075-1081. PMID 30429948 DOI: 10.1021/Acsmedchemlett.8B00372 |
0.311 |
|
| 2018 |
Maskrey TS, Frischling MC, Rice ML, Wipf P. A Five-Component Biginelli-Diels-Alder Cascade Reaction. Frontiers in Chemistry. 6: 376. PMID 30211156 DOI: 10.3389/Fchem.2018.00376 |
0.312 |
|
| 2018 |
Opsenica I, Ajdačić V, Nikolić A, Kerner M, Wipf P. Reevaluation of the Palladium/Carbon-Catalyzed Decarbonylation of Aliphatic Aldehydes Synlett. 29: 1781-1785. DOI: 10.1055/S-0037-1610433 |
0.322 |
|
| 2018 |
McCabe S, Wipf P. Asymmetric Total Synthesis and Biological Evaluation of (+)-Cycloclavine Synthesis. 51: 213-224. DOI: 10.1055/S-0037-1610395 |
0.325 |
|
| 2018 |
Maskrey T, Kristufek T, LaPorte M, Nyalapatla P, Wipf P. A New Synthesis of Gefitinib Synlett. 30: 471-476. DOI: 10.1055/S-0037-1610375 |
0.343 |
|
| 2017 |
Christner S, Guo J, Parise RA, Ringeval M, Hoye AT, Wipf P, Epperly MW, Greenberger JS, Beumer JH, Eiseman JL. Liquid chromatography-tandem mass spectrometric assay for the quantitation of the novel radiation protective agent and radiation mitigator JP4-039 in murine plasma. Journal of Pharmaceutical and Biomedical Analysis. 150: 169-175. PMID 29245086 DOI: 10.1016/J.Jpba.2017.12.023 |
0.738 |
|
| 2017 |
Xu J, Wipf P. Indole synthesis by palladium-catalyzed tandem allylic isomerization - furan Diels-Alder reaction. Organic & Biomolecular Chemistry. PMID 28813061 DOI: 10.1039/C7Ob01654A |
0.328 |
|
| 2017 |
Wissel G, Deng F, Kudryavtsev P, Ghemtio L, Wipf P, Xhaard H, Kidron H. A structure-activity relationship study of ABCC2 inhibitors. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28185990 DOI: 10.1016/J.Ejps.2017.02.005 |
0.31 |
|
| 2017 |
Epperly MW, Sacher JR, Krainz T, Zhang X, Wipf P, Liang M, Fisher R, Li S, Wang H, Greenberger JS. Effectiveness of Analogs of the GS-Nitroxide, JP4-039, as Total Body Irradiation Mitigators. In Vivo (Athens, Greece). 31: 39-43. PMID 28064218 DOI: 10.21873/Invivo.11022 |
0.707 |
|
| 2017 |
Lazo JS, Pekic P, Cheung A, McQueeney K, Salamoun J, Wipf P, Landen CN, Sharlow ER. Abstract 3210: Targeting PTP4A3 phosphatase in ovarian cancer with the potent noncompetitive inhibitor JMS-631-053 Cancer Research. 77: 3210-3210. DOI: 10.1158/1538-7445.Am2017-3210 |
0.316 |
|
| 2017 |
Carreira EM, Brandstätter M, McCabe SR, Wipf P. Synthesis of (–)-Cycloclavine Synfacts. 13: 120-120. DOI: 10.1055/S-0036-1589870 |
0.454 |
|
| 2016 |
McCabe SR, Wipf P. Eight-Step Enantioselective Total Synthesis of (-)-Cycloclavine. Angewandte Chemie (International Ed. in English). PMID 27860203 DOI: 10.1002/Anie.201608820 |
0.358 |
|
| 2016 |
Krainz T, Gaschler MM, Lim C, Sacher JR, Stockwell BR, Wipf P. A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis. Acs Central Science. 2: 653-659. PMID 27725964 DOI: 10.1021/Acscentsci.6B00199 |
0.72 |
|
| 2016 |
Manos-Turvey A, Al-Ashtal HA, Needham PG, Hartline CB, Prichard MN, Wipf P, Brodsky JL. Dihydropyrimidinones and -thiones with improved activity against human polyomavirus family members. Bioorganic & Medicinal Chemistry Letters. PMID 27624078 DOI: 10.1016/J.Bmcl.2016.08.080 |
0.317 |
|
| 2016 |
Milligan JA, Busacca CA, Senanayake CH, Wipf P. Hydrophosphination of Bicyclo[1.1.0]butane-1-carbonitriles. Organic Letters. PMID 27518583 DOI: 10.1021/Acs.Orglett.6B02051 |
0.336 |
|
| 2016 |
Colombo R, Wang Z, Han J, Balachandran R, Daghestani HN, Camarco DP, Vogt A, Day BW, Mendel D, Wipf P. Total Synthesis and Biological Evaluation of Tubulysin Analogs. The Journal of Organic Chemistry. PMID 27447195 DOI: 10.1021/Acs.Joc.6B01314 |
0.79 |
|
| 2016 |
LaPorte MG, Wang Z, Colombo R, Garzan A, Peshkov VA, Liang M, Johnston PA, Schurdak ME, Sen M, Camarco DP, Hua Y, Pollock NI, Lazo JS, Grandis JR, Wipf P, et al. Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27381083 DOI: 10.1016/J.Bmcl.2016.06.017 |
0.673 |
|
| 2016 |
Salamoun JM, McQueeney KE, Patil K, Geib SJ, Sharlow ER, Lazo JS, Wipf P. Photooxygenation of an amino-thienopyridone yields a more potent PTP4A3 inhibitor. Organic & Biomolecular Chemistry. PMID 27291491 DOI: 10.1039/C6Ob00946H |
0.37 |
|
| 2016 |
McCabe SR, Wipf P. Total synthesis, biosynthesis and biological profiles of clavine alkaloids. Organic & Biomolecular Chemistry. PMID 27215547 DOI: 10.1039/C6Ob00878J |
0.317 |
|
| 2016 |
Alverez C, Bulfer SL, Chakrasali R, Chimenti MS, Deshaies RJ, Green N, Kelly M, LaPorte MG, Lewis TS, Liang M, Moore WJ, Neitz RJ, Peshkov VA, Walters MA, Zhang F, ... ... Wipf P, et al. Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway. Acs Medicinal Chemistry Letters. 7: 182-7. PMID 26985295 DOI: 10.1021/Acsmedchemlett.5B00396 |
0.667 |
|
| 2016 |
Alverez C, Bulfer SL, Chakrasali R, Chimenti MS, Deshaies RJ, Green N, Kelly M, LaPorte MG, Lewis TS, Liang M, Moore WJ, Neitz RJ, Peshkov VA, Walters MA, Zhang F, ... ... Wipf P, et al. Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway Acs Medicinal Chemistry Letters. 7: 182-187. DOI: 10.1021/acsmedchemlett.5b00396 |
0.622 |
|
| 2015 |
Alverez C, Arkin MR, Bulfer SL, Colombo R, Kovaliov M, LaPorte MG, Lim C, Liang M, Moore WJ, Neitz RJ, Yan Y, Yue Z, Huryn DM, Wipf P. Structure-Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97. Acs Medicinal Chemistry Letters. 6: 1225-30. PMID 26713109 DOI: 10.1021/Acsmedchemlett.5B00364 |
0.326 |
|
| 2015 |
Wu S, Guo Z, Hopkins CD, Wei N, Chu E, Wipf P, Schmitz JC. Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells. Oncotarget. PMID 26506423 DOI: 10.18632/Oncotarget.5885 |
0.318 |
|
| 2015 |
Ma J, Lim C, Sacher JR, Van Houten B, Qian W, Wipf P. Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells. Bioorganic & Medicinal Chemistry Letters. PMID 26159482 DOI: 10.1016/J.Bmcl.2015.06.073 |
0.706 |
|
| 2015 |
Wissel G, Kudryavtsev P, Ghemtio L, Tammela P, Wipf P, Yliperttula M, Finel M, Urtti A, Kidron H, Xhaard H. Exploring the structure-activity relationships of ABCC2 modulators using a screening approach. Bioorganic & Medicinal Chemistry. 23: 3513-25. PMID 25935289 DOI: 10.1016/J.Bmc.2015.04.029 |
0.306 |
|
| 2015 |
Walczak MA, Krainz T, Wipf P. Ring-strain-enabled reaction discovery: new heterocycles from bicyclo[1.1.0]butanes. Accounts of Chemical Research. 48: 1149-58. PMID 25775119 DOI: 10.1021/Ar500437H |
0.541 |
|
| 2015 |
Tandon M, Salamoun JM, Carder EJ, Farber E, Xu S, Deng F, Tang H, Wipf P, Wang QJ. SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest. Plos One. 10: e0119346. PMID 25747583 DOI: 10.1371/Journal.Pone.0119346 |
0.318 |
|
| 2015 |
George Rosenker KM, Paquette WD, Johnston PA, Sharlow ER, Vogt A, Bakan A, Lazo JS, Wipf P. Synthesis and biological evaluation of 3-aminoisoquinolin-1(2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B. Bioorganic & Medicinal Chemistry. 23: 2810-8. PMID 25703307 DOI: 10.1016/J.Bmc.2015.01.043 |
0.365 |
|
| 2015 |
Qian W, Salamoun J, Wang J, Roginskaya V, Houten BV, Wipf P. Abstract 5344: Novel thioxodihydroquinazolinone small molecules for combination with platinum drugs to reverse platinum resistance through inducing mitochondrial apoptosis independent of Bax and Bak Cancer Research. 75: 5344-5344. DOI: 10.1158/1538-7445.Am2015-5344 |
0.302 |
|
| 2015 |
Brito GA, Sarotti AM, Wipf P, Pilli RA. Cascade cyclization triggered by imine formation. Formal synthesis of the alkaloid (±)-stemoamide and its 9a-epimer Tetrahedron Letters. 56: 6664-6668. DOI: 10.1016/J.Tetlet.2015.10.017 |
0.315 |
|
| 2015 |
Ma J, Lim C, Sacher JR, Van Houten B, Qian W, Wipf P. Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells Bioorganic and Medicinal Chemistry Letters. DOI: 10.1016/j.bmcl.2015.06.073 |
0.674 |
|
| 2014 |
Escobales N, Nuñez RE, Jang S, Parodi-Rullan R, Ayala-Peña S, Sacher JR, Skoda EM, Wipf P, Frontera W, Javadov S. Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats. Journal of Molecular and Cellular Cardiology. 77: 136-46. PMID 25451170 DOI: 10.1016/J.Yjmcc.2014.10.009 |
0.694 |
|
| 2014 |
Ireland AW, Gobillot TA, Gupta T, Seguin SP, Liang M, Resnick L, Goldberg MT, Manos-Turvey A, Pipas JM, Wipf P, Brodsky JL. Synthesis and structure–activity relationships of small molecule inhibitors of the simian virus 40 T antigen oncoprotein, an anti-polyomaviral target. Bioorganic & Medicinal Chemistry. 22: 6490-502. PMID 25440730 DOI: 10.1016/J.Bmc.2014.09.019 |
0.304 |
|
| 2014 |
LaPorte MG, da Paz Lima DJ, Zhang F, Sen M, Grandis JR, Camarco D, Hua Y, Johnston PA, Lazo JS, Resnick LO, Wipf P, Huryn DM. 2-Guanidinoquinazolines as new inhibitors of the STAT3 pathway. Bioorganic & Medicinal Chemistry Letters. 24: 5081-5. PMID 25288188 DOI: 10.1016/J.Bmcl.2014.09.001 |
0.335 |
|
| 2014 |
Busacca CA, Milligan JA, Rattanangkool E, Ramavarapu C, Chen A, Saha AK, Li Z, Lee H, Geib SJ, Wang G, Senanayake CH, Wipf P. Synthesis of phosphaguanidines by hydrophosphination of carbodiimides with phosphine boranes. The Journal of Organic Chemistry. 79: 9878-87. PMID 25271367 DOI: 10.1021/Jo501841S |
0.351 |
|
| 2014 |
Skoda EM, Sacher JR, Kazancioglu MZ, Saha J, Wipf P. An uncharged oxetanyl sulfoxide as a covalent modifier for improving aqueous solubility. Acs Medicinal Chemistry Letters. 5: 900-4. PMID 25147611 DOI: 10.1021/Ml5001504 |
0.708 |
|
| 2014 |
Shinde A, Epperly MW, Cao S, Franicola D, Shields D, Wang H, Wipf P, Sprachman MM, Greenberger JS. Effects of the bifunctional sulfoxide MMS350, a radiation mitigator, on hematopoiesis in long-term bone marrow cultures and on radioresistance of marrow stromal cell lines. In Vivo (Athens, Greece). 28: 457-65. PMID 24982210 |
0.701 |
|
| 2014 |
Salamoun J, Anderson S, Burnett JC, Gussio R, Wipf P. Synthesis of heterocyclic triads by Pd-catalyzed cross-couplings and evaluation of their cell-specific toxicity profile. Organic Letters. 16: 2034-7. PMID 24641272 DOI: 10.1021/Ol500620M |
0.317 |
|
| 2014 |
Faral-Tello P, Liang M, Mahler G, Wipf P, Robello C. Imidazolium compounds are active against all stages of Trypanosoma cruzi. International Journal of Antimicrobial Agents. 43: 262-8. PMID 24359836 DOI: 10.1016/J.Ijantimicag.2013.10.019 |
0.312 |
|
| 2014 |
Colombo R, Jeon KO, Huryn DM, LaPorte MG, Wipf P. A new synthesis of 4,5,6,7-Tetrahydropyrazolo[1,5-c] pyrimidines by a retro-mannich cascade rearrangement Australian Journal of Chemistry. 67: 420-425. DOI: 10.1071/Ch13468 |
0.387 |
|
| 2014 |
Epperly M, Shinde A, Rhieu B, Wang H, Donna S, Franicola D, Zhang X, Dixon T, Wipf P, Sprachman M, Greenberger J. Effects of Radiation Mitigators JP4-039 and MMS350 on Gene Transcripts in Radiosensitive Fanconi Anemia Fancd2-/- (C57Bl/6) Bone Marrow Stromal Cells International Journal of Radiation Oncology*Biology*Physics. 90: S777. DOI: 10.1016/J.Ijrobp.2014.05.2249 |
0.712 |
|
| 2013 |
Kalash R, Epperly MW, Goff J, Dixon T, Sprachman MM, Zhang X, Shields D, Cao S, Franicola D, Wipf P, Berhane H, Wang H, Au J, Greenberger JS. Amelioration of radiation-induced pulmonary fibrosis by a water-soluble bifunctional sulfoxide radiation mitigator (MMS350). Radiation Research. 180: 474-90. PMID 24125487 DOI: 10.1667/Rr3233.1 |
0.722 |
|
| 2013 |
Tandon M, Johnson J, Li Z, Xu S, Wipf P, Wang QJ. New pyrazolopyrimidine inhibitors of protein kinase d as potent anticancer agents for prostate cancer cells. Plos One. 8: e75601. PMID 24086585 DOI: 10.1371/Journal.Pone.0075601 |
0.31 |
|
| 2013 |
Arnold DM, Laporte MG, Anderson SM, Wipf P. Condensation reactions of guanidines with bis-electrophiles: Formation of highly nitrogenous heterocycles. Tetrahedron. 69: 7719-7731. PMID 23976798 DOI: 10.1016/J.Tet.2013.04.127 |
0.371 |
|
| 2013 |
Goff JP, Shields DS, Wang H, Skoda EM, Sprachman MM, Wipf P, Garapati VK, Atkinson J, London B, Lazo JS, Kagan V, Epperly MW, Greenberger JS. Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells. Experimental Hematology. 41: 957-66. PMID 23933481 DOI: 10.1016/J.Exphem.2013.08.001 |
0.736 |
|
| 2013 |
Keffer JL, Huecas S, Hammill JT, Wipf P, Andreu JM, Bewley CA. Chrysophaentins are competitive inhibitors of FtsZ and inhibit Z-ring formation in live bacteria. Bioorganic & Medicinal Chemistry. 21: 5673-8. PMID 23932448 DOI: 10.1016/J.Bmc.2013.07.033 |
0.733 |
|
| 2013 |
Frantz MC, Skoda EM, Sacher JR, Epperly MW, Goff JP, Greenberger JS, Wipf P. Synthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondria. Organic & Biomolecular Chemistry. 11: 4147-53. PMID 23715589 DOI: 10.1039/C3Ob40489G |
0.731 |
|
| 2013 |
Kalash R, Berhane H, Goff J, Houghton F, Epperly MW, Dixon T, Zhang X, Sprachman MM, Wipf P, Franicola D, Wang H, Greenberger JS. Effects of thoracic irradiation on pulmonary endothelial compared to alveolar type-II cells in fibrosis-prone C57BL/6NTac mice. In Vivo (Athens, Greece). 27: 291-7. PMID 23606683 |
0.703 |
|
| 2013 |
Rosenker CJ, Krenske EH, Houk KN, Wipf P. Influence of base and structure in the reversible covalent conjugate addition of thiol to polycyclic enone scaffolds. Organic Letters. 15: 1076-9. PMID 23405884 DOI: 10.1021/Ol400094K |
0.786 |
|
| 2013 |
LaPorte M, Hong KB, Xu J, Wipf P. 5-Hydroxyindoles by intramolecular alkynol-furan diels-alder cycloaddition. The Journal of Organic Chemistry. 78: 167-74. PMID 23136970 DOI: 10.1021/Jo3022605 |
0.331 |
|
| 2013 |
Wipf P, Fang Z, Ferrié L, Ueda M, Walczak MAA, Yan Y, Yang M. Cycloadditions in heterocycle and alkaloid synthesis Pure and Applied Chemistry. 85: 1079-1087. DOI: 10.1351/Pac-Con-12-09-03 |
0.373 |
|
| 2013 |
Tandon M, Johnson J, Farber E, Carder E, Wipf P, Wang QJ. Abstract 2182: Novel ATP-competitive protein kinase D inhibitors: in vitro characterization and SAR analysis. Cancer Research. 73: 2182-2182. DOI: 10.1158/1538-7445.Am2013-2182 |
0.321 |
|
| 2013 |
Zuniga J, Hammill J, Drory O, Nuss J, Burnett J, Gussio R, Wipf P, Bavari S, Brunger A. Structural basis for the inhibition of botulinum neurotoxin serotype A by potent peptidomimetics Toxicon. 68: 103-104. DOI: 10.1016/J.Toxicon.2012.07.122 |
0.717 |
|
| 2013 |
Epperly M, Goff J, Kalash R, Dixon T, Sprachman M, Zhang X, Cao S, Wipf P, Berhane H, Greenberger J. Late Pulmonary Fibrotic Phase Specific Homing of Luciferase+ Bone Marrow Stromal Cells to the Irradiated C57bl/6hnsd Mouse Lung International Journal of Radiation Oncology*Biology*Physics. 87: S113. DOI: 10.1016/J.Ijrobp.2013.06.293 |
0.709 |
|
| 2013 |
Epperly M, Sprachman M, Dixon T, Goff J, Shields D, Zhang X, Wipf P, Greenberger J. MMS350: A Water Soluble Radiation Protector and Mitigator International Journal of Radiation Oncology*Biology*Physics. 87: S640. DOI: 10.1016/J.Ijrobp.2013.06.1694 |
0.705 |
|
| 2013 |
Epperly M, Goff J, Kalash R, Dixon T, Franicola D, Sprachman M, Wipf P, Berhane H, Greenberger J. Reduction of Late Pulmonary Fibrosis in Thoracic-Irradiated C57bl/6hnsd Mice by a Water Soluble Radiation Mitigator MMS-350 International Journal of Radiation Oncology*Biology*Physics. 87: S639-S640. DOI: 10.1016/J.Ijrobp.2013.06.1692 |
0.71 |
|
| 2013 |
Rosenker CJ, Krenske EH, Houk KN, Wipf P. ChemInform Abstract: Influence of Base and Structure in the Reversible Covalent Conjugate Addition of Thiol to Polycyclic Enone Scaffolds. Cheminform. 44: no-no. DOI: 10.1002/chin.201326101 |
0.784 |
|
| 2012 |
Tandon M, Wang L, Xu Q, Xie X, Wipf P, Wang QJ. A targeted library screen reveals a new inhibitor scaffold for protein kinase D. Plos One. 7: e44653. PMID 23028574 DOI: 10.1371/Journal.Pone.0044653 |
0.331 |
|
| 2012 |
Miller B, Mao S, Rosenker KM, Pierce JG, Wipf P. Synthesis of a library of tricyclic azepinoisoindolinones. Beilstein Journal of Organic Chemistry. 8: 1091-7. PMID 23019435 DOI: 10.3762/Bjoc.8.120 |
0.628 |
|
| 2012 |
Keffer JL, Hammill JT, Lloyd JR, Plaza A, Wipf P, Bewley CA. Geographic variability and anti-staphylococcal activity of the chrysophaentins and their synthetic fragments. Marine Drugs. 10: 1103-25. PMID 22822360 DOI: 10.3390/Md10051103 |
0.726 |
|
| 2012 |
Cao L, Maciejewski JP, Elzner S, Amantini D, Wipf P. Synthesis of 1,2,4-triazines and the triazinoisoquinolinedione DEF ring system of noelaquinone. Organic & Biomolecular Chemistry. 10: 5811-4. PMID 22473572 DOI: 10.1039/C2Ob25353D |
0.591 |
|
| 2012 |
Skoda EM, Davis GC, Wipf P. Allylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide Isosteres. Organic Process Research & Development. 16: 26-34. PMID 22323894 DOI: 10.1021/Op2002613 |
0.346 |
|
| 2012 |
Sprachman MM, Wipf P. A bifunctional dimethylsulfoxide substitute enhances the aqueous solubility of small organic molecules. Assay and Drug Development Technologies. 10: 269-77. PMID 22192308 DOI: 10.1089/Adt.2011.0421 |
0.748 |
|
| 2012 |
Goff JP, Dixon TM, Epperly MW, Sprachman M, Wipf P, Zhang X, Greenberger JS. Serial Imaging of Luciferase Positive Bone Marrow Stromal Cell Migration to Form Radiation Pulmonary Fibrosis Blood. 120: 4734-4734. DOI: 10.1182/Blood.V120.21.4734.4734 |
0.721 |
|
| 2012 |
Berhane H, Epperly MW, Cao S, Zhang X, Shields D, Goff J, Sprachman M, Wipf P, Li S, Gao X, Greenberger JS. Diminished Oxidative Stress Responses in Bone Marrow Stromal Cell Lines Derived From Fanconi Anemia (Fanc-D2−/−) Mice Blood. 120: 4398-4398. DOI: 10.1182/Blood.V120.21.4398.4398 |
0.728 |
|
| 2012 |
Pizzo C, Faral-Tello P, Salinas G, Fló M, Robello C, Wipf P, Graciela Mahler S. Selenosemicarbazones as potent cruzipain inhibitors and their antiparasitic properties against Trypanosoma cruzi Medchemcomm. 3: 362-368. DOI: 10.1039/C2Md00283C |
0.308 |
|
| 2012 |
Hoye AT, Davoren JE, Wipf P, Fink MP, Kagan VE. Correction to Targeting Mitochondria Accounts of Chemical Research. 45: 2222-2222. DOI: 10.1021/Ar300293E |
0.736 |
|
| 2012 |
Goff J, Shields D, Wang H, Skoda E, Sprachman M, Wipf P, Atkinson J, Epperly M, Kagan V, Lazo J. Identification of Ionizing Irradiation Damage Mitigators by Evaluation of Clonogenic Survival of Human Umbilical Cord Blood Progenitor Cells International Journal of Radiation Oncology*Biology*Physics. 84: S680. DOI: 10.1016/J.Ijrobp.2012.07.1817 |
0.709 |
|
| 2012 |
Sprachman M, Epperly M, Wipf P, Shields D, Dixon T, Cao S, Goff J, Greenberger J. MMS350: A Novel Bifunctional Sulfoxide With Radiation Protection and Mitigation Properties International Journal of Radiation Oncology*Biology*Physics. 84: S680. DOI: 10.1016/J.Ijrobp.2012.07.1816 |
0.72 |
|
| 2011 |
George KM, Frantz MC, Bravo-Altamirano K, Lavalle CR, Tandon M, Leimgruber S, Sharlow ER, Lazo JS, Wang QJ, Wipf P. Design, Synthesis, and Biological Evaluation of PKD Inhibitors. Pharmaceutics. 3: 186-228. PMID 22267986 DOI: 10.3390/Pharmaceutics3020186 |
0.304 |
|
| 2011 |
Sharlow ER, Mustata Wilson G, Close D, Leimgruber S, Tandon M, Reed RB, Shun TY, Wang QJ, Wipf P, Lazo JS. Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity. Plos One. 6: e25134. PMID 21998636 DOI: 10.1371/Journal.Pone.0025134 |
0.355 |
|
| 2011 |
Braunstein MJ, Scott SS, Scott CM, Behrman S, Walter P, Wipf P, Coplan JD, Chrico W, Joseph D, Brodsky JL, Batuman O. Antimyeloma Effects of the Heat Shock Protein 70 Molecular Chaperone Inhibitor MAL3-101. Journal of Oncology. 2011: 232037. PMID 21977030 DOI: 10.1155/2011/232037 |
0.304 |
|
| 2011 |
Wipf P, Manojlovic MD. Homoallylic amines by reductive inter- and intramolecular coupling of allenes and nitriles. Beilstein Journal of Organic Chemistry. 7: 824-30. PMID 21804878 DOI: 10.3762/Bjoc.7.94 |
0.317 |
|
| 2011 |
Hopkins CD, Schmitz JC, Chu E, Wipf P. Total synthesis of (-)-CP2-disorazole C1. Organic Letters. 13: 4088-91. PMID 21739942 DOI: 10.1021/Ol2015994 |
0.382 |
|
| 2011 |
Saiz C, Wipf P, Mahler G. Synthesis and ring-chain-ring tautomerism of bisoxazolidines, thiazolidinyloxazolidines, and spirothiazolidines. The Journal of Organic Chemistry. 76: 5738-46. PMID 21634420 DOI: 10.1021/Jo2008498 |
0.324 |
|
| 2011 |
Bravo-Altamirano K, George KM, Frantz MC, Lavalle CR, Tandon M, Leimgruber S, Sharlow ER, Lazo JS, Wang QJ, Wipf P. Synthesis and Structure-Activity Relationships of Benzothienothiazepinone Inhibitors of Protein Kinase D. Acs Medicinal Chemistry Letters. 2: 154-159. PMID 21617763 DOI: 10.1021/Ml100230N |
0.349 |
|
| 2011 |
Zaware N, Laporte MG, Farid R, Liu L, Wipf P, Floreancig PE. Diversity-oriented synthesis of a library of substituted tetrahydropyrones using oxidative carbon-hydrogen bond activation and click chemistry. Molecules (Basel, Switzerland). 16: 3648-62. PMID 21540794 DOI: 10.3390/Molecules16053648 |
0.345 |
|
| 2011 |
Petronijevic FR, Wipf P. Total synthesis of (±)-cycloclavine and (±)-5-epi-cycloclavine. Journal of the American Chemical Society. 133: 7704-7. PMID 21517102 DOI: 10.1021/Ja2026882 |
0.792 |
|
| 2011 |
Hoye AT, Wipf P. Total synthesis of (-)-sessilifoliamide C and (-)-8-epi-stemoamide. Organic Letters. 13: 2634-7. PMID 21510628 DOI: 10.1021/Ol200743U |
0.778 |
|
| 2011 |
Huryn DM, Brodsky JL, Brummond KM, Chambers PG, Eyer B, Ireland AW, Kawasumi M, Laporte MG, Lloyd K, Manteau B, Nghiem P, Quade B, Seguin SP, Wipf P. Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators. Proceedings of the National Academy of Sciences of the United States of America. 108: 6757-62. PMID 21502524 DOI: 10.1073/Pnas.1015251108 |
0.346 |
|
| 2011 |
Frantz MC, Pierce JG, Pierce JM, Kangying L, Qingwei W, Johnson M, Wipf P. Large-scale asymmetric synthesis of the bioprotective agent JP4-039 and analogs. Organic Letters. 13: 2318-21. PMID 21452836 DOI: 10.1021/Ol200567P |
0.589 |
|
| 2011 |
Pizzo C, Saiz C, Talevi A, Gavernet L, Palestro P, Bellera C, Blanch LB, Benítez D, Cazzulo JJ, Chidichimo A, Wipf P, Mahler SG. Synthesis of 2-hydrazolyl-4-thiazolidinones based on multicomponent reactions and biological evaluation against Trypanosoma Cruzi. Chemical Biology & Drug Design. 77: 166-72. PMID 21251233 DOI: 10.1111/J.1747-0285.2010.01071.X |
0.338 |
|
| 2011 |
MacIejewski JP, Wipf P. Titanocene(III)-catalyzed conversion of N-(epoxyalkyl)anilines into indolines Arkivoc. 2011: 92-119. DOI: 10.3998/Ark.5550190.0012.609 |
0.555 |
|
| 2011 |
Frantz M-, Pierce JG, Pierce JM, Kangying L, Qingwei W, Johnson M, Wipf P. Asymmetric Synthesis of the Bioprotective Agent JP4-039 Synfacts. 2011: 700-700. DOI: 10.1055/S-0030-1260483 |
0.584 |
|
| 2011 |
Rosenker CJ, Wipf P. Transmetalation Reactions Producing Organocopper Compounds Patai's Chemistry of Functional Groups. DOI: 10.1002/9780470682531.Pat0443 |
0.778 |
|
| 2010 |
Wipf P, George KM. Regioselective Palladium-Catalyzed Cross-Coupling Reactions of 2,4,7-Trichloroquinazoline. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 2010: 644-648. PMID 21116479 DOI: 10.1055/S-0029-1219391 |
0.319 |
|
| 2010 |
Wang XJ, Zhang L, Krishnamurthy D, Senanayake CH, Wipf P. General solution to the synthesis of N-2-substituted 1,2,3-triazoles. Organic Letters. 12: 4632-5. PMID 20863126 DOI: 10.1021/Ol101965A |
0.328 |
|
| 2010 |
Hammill JT, Contreras-García J, Virshup AM, Beratan D, Yang W, Wipf P. Synthesis and chemical diversity analysis of bicyclo[3.3.1]non-3-en-2-ones. Tetrahedron. 66: 5852-5862. PMID 20798897 DOI: 10.1016/J.Tet.2010.04.112 |
0.747 |
|
| 2010 |
Mishra JK, Wipf P, Sinha SC. Studies toward a library of tetrahydrofurans: click and MCR products of mono- and bis-tetrahydrofurans. Journal of Combinatorial Chemistry. 12: 609-12. PMID 20614864 DOI: 10.1021/Cc1000709 |
0.348 |
|
| 2010 |
Zuniga JE, Hammill JT, Drory O, Nuss JE, Burnett JC, Gussio R, Wipf P, Bavari S, Brunger AT. Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A. Plos One. 5: e11378. PMID 20614028 DOI: 10.1371/Journal.Pone.0011378 |
0.718 |
|
| 2010 |
Lavalle CR, Bravo-Altamirano K, Giridhar KV, Chen J, Sharlow E, Lazo JS, Wipf P, Wang QJ. Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility. Bmc Chemical Biology. 10: 5. PMID 20444281 DOI: 10.1186/1472-6769-10-5 |
0.326 |
|
| 2010 |
Milner E, McCalmont W, Bhonsle J, Caridha D, Cobar J, Gardner S, Gerena L, Goodine D, Lanteri C, Melendez V, Roncal N, Sousa J, Wipf P, Dow GS. Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols. Malaria Journal. 9: 51. PMID 20149249 DOI: 10.1186/1475-2875-9-51 |
0.316 |
|
| 2010 |
Milner E, McCalmont W, Bhonsle J, Caridha D, Carroll D, Gardner S, Gerena L, Gettayacamin M, Lanteri C, Luong T, Melendez V, Moon J, Roncal N, Sousa J, Tungtaeng A, ... Wipf P, et al. Structure-activity relationships amongst 4-position quinoline methanol antimalarials that inhibit the growth of drug sensitive and resistant strains of Plasmodium falciparum. Bioorganic & Medicinal Chemistry Letters. 20: 1347-51. PMID 20097070 DOI: 10.1016/J.Bmcl.2010.01.001 |
0.304 |
|
| 2010 |
Soares KM, Blackmon N, Shun TY, Shinde SN, Takyi HK, Wipf P, Lazo JS, Johnston PA. Profiling the NIH Small Molecule Repository for compounds that generate H2O2 by redox cycling in reducing environments. Assay and Drug Development Technologies. 8: 152-74. PMID 20070233 DOI: 10.1089/Adt.2009.0247 |
0.313 |
|
| 2010 |
Lazo JS, Reese CE, Vogt A, Vollmer LL, Kitchens CA, Günther E, Graham TH, Hopkins CD, Wipf P. Identifying a resistance determinant for the antimitotic natural products disorazole C1 and A1. The Journal of Pharmacology and Experimental Therapeutics. 332: 906-11. PMID 20008956 DOI: 10.1124/Jpet.109.162842 |
0.65 |
|
| 2010 |
Mo T, Mi X, Milner EE, Dow GS, Wipf P. Synthesis of an 8-pentafluorosulfanyl analog of the antimalarial agent mefloquine Tetrahedron Letters. 51: 5137-5140. DOI: 10.1016/J.Tetlet.2010.07.113 |
0.355 |
|
| 2010 |
Rosenker CJ, Wipf P. ChemInform Abstract: Transmetalation Reactions Producing Organocopper Compounds Cheminform. 42: no-no. DOI: 10.1002/chin.201103255 |
0.784 |
|
| 2010 |
Wipf P, Uto Y, Yoshimura S. ChemInform Abstract: Total Synthesis of a Stereoisomer of Bistramide C and Assignment of Configuration of the Natural Product. Cheminform. 33: no-no. DOI: 10.1002/chin.200232235 |
0.528 |
|
| 2010 |
Wipf P, Graham TH. ChemInform Abstract: Synthesis of the C1′ -C11′ Segment of Leucascandrolide A. Cheminform. 32: no-no. DOI: 10.1002/chin.200137231 |
0.626 |
|
| 2010 |
Wipf P, Hopkins CR. ChemInform Abstract: Enantioselective Synthesis of the AB-Ring System of the Antitumor Antibiotic Tetrazomine. Cheminform. 32: no-no. DOI: 10.1002/chin.200137226 |
0.524 |
|
| 2010 |
Phillips AJ, Uto Y, Wipf P, Reno MJ, Williams DR. ChemInform Abstract: Synthesis of Functionalized Oxazolines and Oxazoles with DAST and Deoxo-Fluor. Cheminform. 31: no-no. DOI: 10.1002/chin.200033121 |
0.623 |
|
| 2010 |
Wipf P, Uto Y. ChemInform Abstract: Total Synthesis and Revision of Stereochemistry of the Marine Metabolite Trunkamide A. Cheminform. 31: no-no. DOI: 10.1002/chin.200022195 |
0.535 |
|
| 2010 |
Wipf P, Hopkins CR. ChemInform Abstract: Efficient Synthesis of 1,4-Dihydro-2H-isoquinoline-3,5,8-triones via Cyclobutene Ring Expansion. Cheminform. 31: no-no. DOI: 10.1002/chin.200002165 |
0.514 |
|
| 2010 |
Wipf P, Uto Y. ChemInform Abstract: Total Synthesis of the Putative Structure (I) of the Marine Metabolite Trunkamide A. Cheminform. 30: no-no. DOI: 10.1002/chin.199940172 |
0.528 |
|
| 2010 |
Wipf P, Rahman LT, Rector SR. ChemInform Abstract: A General Strategy for Five-Membered Heterocycle Synthesis by Cycloelimination of Alkynyl Ketones, Amides, and Thioamides. Cheminform. 30: no-no. DOI: 10.1002/chin.199913059 |
0.803 |
|
| 2010 |
IRELAND RE, WIPF P, XIANG J. ChemInform Abstract: Stereochemical Control in the Ester Enolate Claisen Rearrangement. Part 2. Chairlike vs Boatlike Transition-State Selection. Cheminform. 22: no-no. DOI: 10.1002/chin.199141054 |
0.46 |
|
| 2010 |
IRELAND RE, WIPF P, ARMSTRONG JDI. ChemInform Abstract: Stereochemical Control in the Ester Enolate Claisen Rearrangement. Part 1. Stereoselectivity in Silyl Ketene Acetal Formation. Cheminform. 22: no-no. DOI: 10.1002/chin.199131227 |
0.506 |
|
| 2010 |
Zhao B, Du H, Fu R, Shi Y, Buck EE, Wipf P. Pd(0)-catalyzed asymmetric allylic and homoallylic diamination of 4-phenyl-1-butene with DI-tert-butyldiaziridinone Organic Syntheses. 87: 263-274. |
0.657 |
|
| 2009 |
Wipf P, Xiao J, Stephenson CR. Peptide-Like Molecules (PLMs): A Journey from Peptide Bond Isosteres to Gramicidin S Mimetics and Mitochondrial Targeting Agents. Chimia. 63: 764-775. PMID 20725595 DOI: 10.2533/Chimia.2009.764 |
0.607 |
|
| 2009 |
Liang M, Saiz C, Pizzo C, Wipf P. Synthesis of pyrrolo[1,3]diazepines by a dipolar cycloaddition - retro-Mannich domino reaction. Tetrahedron Letters. 50: 6810-6813. PMID 20160922 DOI: 10.1016/J.Tetlet.2009.09.107 |
0.379 |
|
| 2009 |
Sharlow ER, Close D, Shun T, Leimgruber S, Reed R, Mustata G, Wipf P, Johnson J, O'Neil M, Grögl M, Magill AJ, Lazo JS. Identification of potent chemotypes targeting Leishmania major using a high-throughput, low-stringency, computationally enhanced, small molecule screen. Plos Neglected Tropical Diseases. 3: e540. PMID 19888337 DOI: 10.1371/Journal.Pntd.0000540 |
0.304 |
|
| 2009 |
Wipf P, Arnold D, Carter K, Dong S, Johnston PA, Sharlow E, Lazo JS, Huryn D. A case study from the chemistry core of the Pittsburgh Molecular Library Screening Center: the Polo-like kinase polo-box domain (Plk1-PBD). Current Topics in Medicinal Chemistry. 9: 1194-205. PMID 19807663 DOI: 10.2174/156802609789753590 |
0.302 |
|
| 2009 |
Wipf P, Mo T, Geib SJ, Caridha D, Dow GS, Gerena L, Roncal N, Milner EE. Synthesis and biological evaluation of the first pentafluorosulfanyl analogs of mefloquine. Organic & Biomolecular Chemistry. 7: 4163-5. PMID 19795052 DOI: 10.1039/B911483A |
0.349 |
|
| 2009 |
Rajagopalan MS, Gupta K, Epperly MW, Franicola D, Zhang X, Wang H, Zhao H, Tyurin VA, Pierce JG, Kagan VE, Wipf P, Kanai AJ, Greenberger JS. The mitochondria-targeted nitroxide JP4-039 augments potentially lethal irradiation damage repair. In Vivo (Athens, Greece). 23: 717-26. PMID 19779106 |
0.511 |
|
| 2009 |
Saiz C, Pizzo C, Manta E, Wipf P, Mahler SG. Microwave assisted tandem reactions for the synthesis of 2-hydrazolyl-4-thiazolidinones. Tetrahedron Letters. 50: 901-904. PMID 19756224 DOI: 10.1016/J.Tetlet.2008.12.020 |
0.345 |
|
| 2009 |
Burnett JC, Wang C, Nuss JE, Nguyen TL, Hermone AR, Schmidt JJ, Gussio R, Wipf P, Bavari S. Pharmacophore-guided lead optimization: the rational design of a non-zinc coordinating, sub-micromolar inhibitor of the botulinum neurotoxin serotype a metalloprotease. Bioorganic & Medicinal Chemistry Letters. 19: 5811-3. PMID 19703771 DOI: 10.1016/J.Bmcl.2009.01.111 |
0.69 |
|
| 2009 |
Saiz C, Wipf P, Manta E, Mahler G. Reversible thiazolidine exchange: a new reaction suitable for dynamic combinatorial chemistry. Organic Letters. 11: 3170-3. PMID 19585999 DOI: 10.1021/Ol901104A |
0.304 |
|
| 2009 |
Johnston PA, Foster CA, Tierno MB, Shun TY, Shinde SN, Paquette WD, Brummond KM, Wipf P, Lazo JS. Cdc25B dual-specificity phosphatase inhibitors identified in a high-throughput screen of the NIH compound library. Assay and Drug Development Technologies. 7: 250-65. PMID 19530895 DOI: 10.1089/Adt.2008.186 |
0.326 |
|
| 2009 |
Walczak MA, Shin BK, Wipf P, Saxena S. An ESR analysis of the mechanism of pericyclic reactions of bicyclobutane. Organic & Biomolecular Chemistry. 7: 2363-6. PMID 19462047 DOI: 10.1039/B815469B |
0.458 |
|
| 2009 |
Hopkins CD, Wipf P. Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides. Natural Product Reports. 26: 585-601. PMID 19387496 DOI: 10.1039/B813799B |
0.316 |
|
| 2009 |
Sarachine MJ, Janjic JM, Wipf P, Day BW. Biphenyl C-cyclopropylalkylamides: New scaffolds for targeting estrogen receptor beta. Bioorganic & Medicinal Chemistry Letters. 19: 2404-8. PMID 19356928 DOI: 10.1016/J.Bmcl.2009.03.075 |
0.771 |
|
| 2009 |
Werner S, Nielsen SD, Wipf P, Turner DM, Chambers PG, Geib SJ, Curran DP, Zhang W. Fluorous parallel synthesis of a piperazinedione-fused tricyclic compound library. Journal of Combinatorial Chemistry. 11: 452-9. PMID 19301852 DOI: 10.1021/Cc900003Q |
0.38 |
|
| 2009 |
Kagan VE, Bayir HA, Belikova NA, Kapralov O, Tyurina YY, Tyurin VA, Jiang J, Stoyanovsky DA, Wipf P, Kochanek PM, Greenberger JS, Pitt B, Shvedova AA, Borisenko G. Cytochrome c/cardiolipin relations in mitochondria: a kiss of death. Free Radical Biology & Medicine. 46: 1439-53. PMID 19285551 DOI: 10.1016/J.Freeradbiomed.2009.03.004 |
0.315 |
|
| 2009 |
Chiang AN, Valderramos JC, Balachandran R, Chovatiya RJ, Mead BP, Schneider C, Bell SL, Klein MG, Huryn DM, Chen XS, Day BW, Fidock DA, Wipf P, Brodsky JL. Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum. Bioorganic & Medicinal Chemistry. 17: 1527-33. PMID 19195901 DOI: 10.1016/J.Bmc.2009.01.024 |
0.546 |
|
| 2009 |
Petronijevic F, Timmons C, Cuzzupe A, Wipf P. A microwave assisted intramolecular-furan-Diels-Alder approach to 4-substituted indoles. Chemical Communications (Cambridge, England). 104-6. PMID 19082013 DOI: 10.1039/B816989F |
0.803 |
|
| 2009 |
Tierno MB, Kitchens CA, Petrik B, Graham TH, Wipf P, Xu FL, Saunders WS, Raccor BS, Balachandran R, Day BW, Stout JR, Walczak CE, Ducruet AP, Reese CE, Lazo JS. Microtubule binding and disruption and induction of premature senescence by disorazole C(1). The Journal of Pharmacology and Experimental Therapeutics. 328: 715-22. PMID 19066338 DOI: 10.1124/Jpet.108.147330 |
0.733 |
|
| 2009 |
Kagan VE, Bayir A, Bayir H, Stoyanovsky D, Borisenko GG, Tyurina YY, Wipf P, Atkinson J, Greenberger JS, Chapkin RS, Belikova NA. Mitochondria-targeted disruptors and inhibitors of cytochrome c/cardiolipin peroxidase complexes: a new strategy in anti-apoptotic drug discovery. Molecular Nutrition & Food Research. 53: 104-14. PMID 18979502 DOI: 10.1002/Mnfr.200700402 |
0.304 |
|
| 2009 |
Wang C, Widom J, Petronijevic F, Burnett JC, Nuss JE, Bavari S, Gussio R, Wipf P. Synthesis and biological evaluation of inhibitors of botulinum neurotoxin metalloprotease Heterocycles. 79: 487-520. DOI: 10.3987/Com-08-S(D)8 |
0.801 |
|
| 2009 |
Scarone L, Fajardo J, Saldaña J, Domínguez L, Espósito P, Demastteis S, Wipf P, Manta E, Serra G. Synthesis and evaluation of anthelmintic and cytotoxic properties of [2,5']bis-1,3-azole analogs of bengazoles Letters in Drug Design and Discovery. 6: 413-419. DOI: 10.2174/157018009789057553 |
0.329 |
|
| 2009 |
Petronijevic F, Timmons C, Cuzzupe A, Wipf P. Microwave-Assisted Diels-Alder Approach to 4-SubstitutedIndoles Synfacts. 2009: 369-369. DOI: 10.1055/S-0028-1087881 |
0.761 |
|
| 2009 |
Wang C, Widom J, Petronijevic F, Burnett JC, Nuss JE, Bavari S, Gussio R, Wipf P. ChemInform Abstract: Synthesis and Biological Evaluation of Inhibitors of Botulinum Neurotoxin Metalloprotease. Cheminform. 40. DOI: 10.1002/chin.200941110 |
0.687 |
|
| 2009 |
Wipf P, Maciejewski JP. ChemInform Abstract: Titanocene(III)-Catalyzed Formation of Indolines and Azaindolines. Cheminform. 40. DOI: 10.1002/chin.200907122 |
0.495 |
|
| 2009 |
Du H, Zhao B, Shi Y, Buck EE, Wipf P. Pd(0)-catalyzed diamination of trans-1-phenyl-1,3-butadiene with di-tert-butyldiaziridinone as nitrogen source Organic Syntheses. 86: 315-324. |
0.653 |
|
| 2008 |
Ueda M, Walczak MA, Wipf P. Formal Alder-ene reaction of a bicyclo[1.1.0]butane in the synthesis of the tricyclic quaternary ammonium core of daphniglaucins. Tetrahedron Letters. 49: 5986-5989. PMID 19129907 DOI: 10.1016/J.Tetlet.2008.07.179 |
0.53 |
|
| 2008 |
Hermone AR, Burnett JC, Nuss JE, Tressler LE, Nguyen TL, Solaja BA, Vennerstrom JL, Schmidt JJ, Wipf P, Bavari S, Gussio R. Three-dimensional database mining identifies a unique chemotype that unites structurally diverse botulinum neurotoxin serotype A inhibitors in a three-zone pharmacophore. Chemmedchem. 3: 1905-12. PMID 19006141 DOI: 10.1002/Cmdc.200800241 |
0.308 |
|
| 2008 |
Bakan A, Lazo JS, Wipf P, Brummond KM, Bahar I. Toward a molecular understanding of the interaction of dual specificity phosphatases with substrates: insights from structure-based modeling and high throughput screening. Current Medicinal Chemistry. 15: 2536-44. PMID 18855677 DOI: 10.2174/092986708785909003 |
0.302 |
|
| 2008 |
Sharlow ER, Giridhar KV, LaValle CR, Chen J, Leimgruber S, Barrett R, Bravo-Altamirano K, Wipf P, Lazo JS, Wang QJ. Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone. The Journal of Biological Chemistry. 283: 33516-26. PMID 18829454 DOI: 10.1074/Jbc.M805358200 |
0.324 |
|
| 2008 |
Wipf P, Maciejewski JP. Titanocene(III)-catalyzed formation of indolines and azaindolines. Organic Letters. 10: 4383-6. PMID 18781767 DOI: 10.1021/Ol801860S |
0.554 |
|
| 2008 |
Pierce JG, Kasi D, Fushimi M, Cuzzupe A, Wipf P. Synthesis of hydroxylated bicyclic amino acids from L-tyrosine: octahydro-1H-indole carboxylates. The Journal of Organic Chemistry. 73: 7807-10. PMID 18767800 DOI: 10.1021/Jo801552J |
0.561 |
|
| 2008 |
Walczak MA, Wipf P. Rhodium(I)-catalyzed cycloisomerizations of bicyclobutanes. Journal of the American Chemical Society. 130: 6924-5. PMID 18461936 DOI: 10.1021/Ja802906K |
0.512 |
|
| 2008 |
Jiang J, Belikova NA, Hoye AT, Zhao Q, Epperly MW, Greenberger JS, Wipf P, Kagan VE. A mitochondria-targeted nitroxide/hemigramicidin S conjugate protects mouse embryonic cells against gamma irradiation. International Journal of Radiation Oncology, Biology, Physics. 70: 816-25. PMID 18262096 DOI: 10.1016/J.Ijrobp.2007.10.047 |
0.76 |
|
| 2008 |
Vogt A, McDonald PR, Tamewitz A, Sikorski RP, Wipf P, Skoko JJ, Lazo JS. A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells. Molecular Cancer Therapeutics. 7: 330-40. PMID 18245669 DOI: 10.1158/1535-7163.Mct-07-2165 |
0.325 |
|
| 2008 |
Balachandran R, Hopkins TD, Thomas CA, Wipf P, Day BW. Tubulin-perturbing naphthoquinone spiroketals. Chemical Biology & Drug Design. 71: 117-24. PMID 18194192 DOI: 10.1111/J.1747-0285.2007.00616.X |
0.548 |
|
| 2008 |
Hoye AT, Davoren JE, Wipf P, Fink MP, Kagan VE. Targeting mitochondria. Accounts of Chemical Research. 41: 87-97. PMID 18193822 DOI: 10.1021/ar700135m |
0.752 |
|
| 2008 |
Wright CM, Chovatiya RJ, Jameson NE, Turner DM, Zhu G, Werner S, Huryn DM, Pipas JM, Day BW, Wipf P, Brodsky JL. Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation. Bioorganic & Medicinal Chemistry. 16: 3291-301. PMID 18164205 DOI: 10.1016/J.Bmc.2007.12.014 |
0.542 |
|
| 2008 |
Braunstein MJ, Scott CM, Behrman S, Walter P, Wipf P, Smith EL, Scott SS, Klueppelberg HU, Brodsky JL, Batuman O. Targeting Hsp70 in Multiple Myeloma Induces Synergistic Cytotoxicity with Inhibitors of the Proteasome and of Hsp90 Blood. 112: 5160-5160. DOI: 10.1182/Blood.V112.11.5160.5160 |
0.31 |
|
| 2008 |
Gupta K, Epperly MW, Franicola D, Zhang X, Pierce JG, Wipf P, Greenberger J. Mitigation of Irradiation Induced Potentially Lethal Damage (PLD) in Hematopoietic Cells by Mitochondrial Localized GS-Nitroxide, JP4-039 Blood. 112: 4725-4725. DOI: 10.1182/Blood.V112.11.4725.4725 |
0.539 |
|
| 2008 |
Epperly MW, Pierce JG, Dixon T, Franicola D, Nie S, Zhang X, Vlasova II, Wipf P, Kagan V, Greenberger J. A Mitochondrially Targeted Nitroxide JP4-039 Protects and Mitigates against Total Body Irradiation Induced Hematopoietic Syndrome Blood. 112: 4721-4721. DOI: 10.1182/Blood.V112.11.4721.4721 |
0.566 |
|
| 2008 |
Epperly M, Pierce J, Dixon T, Franicola D, Wipf P, Greenberger J. The Mitochondrial Targeted GS-Nitroxide JP4-039 is Radioprotective In Vitro and In Vivo International Journal of Radiation Oncology*Biology*Physics. 72: S82. DOI: 10.1016/J.Ijrobp.2008.06.952 |
0.54 |
|
| 2008 |
Wipf P, Jayasuriya N. Chiral ligand optimization in the asymmetric zirconium-zinc transmetalation aldehyde addition reaction Chirality. 20: 425-430. DOI: 10.1002/Chir.20468 |
0.306 |
|
| 2008 |
Pierce JG, Waller DL, Wipf P. ChemInform Abstract: Synthesis of Functionalized Isoindolinones: Addition of in situ Generated Organoalanes to Acyliminium Ions. Cheminform. 39. DOI: 10.1002/chin.200806106 |
0.52 |
|
| 2007 |
Pierce JG, Waller DL, Wipf P. Synthesis of Functionalized Isoindolinones: Addition of In Situ Generated Organoalanes to Acyliminium Ions. Journal of Organometallic Chemistry. 692: 4618-4629. PMID 19684878 DOI: 10.1016/J.Jorganchem.2007.05.035 |
0.593 |
|
| 2007 |
Guo J, Parise RA, Joseph E, Lan J, Pan SS, Joo B, Egorin MJ, Wipf P, Lazo JS, Eiseman JL. Pharmacology and antitumor activity of a quinolinedione Cdc25 phosphatase inhibitor DA3003-1 (NSC 663284). Anticancer Research. 27: 3067-73. PMID 17970046 |
0.519 |
|
| 2007 |
Fink MP, Macias CA, Xiao J, Tyurina YY, Delude RL, Greenberger JS, Kagan VE, Wipf P. Hemigramicidin-TEMPO conjugates: novel mitochondria-targeted antioxidants. Critical Care Medicine. 35: S461-7. PMID 17713394 DOI: 10.1097/01.Ccm.0000279192.96303.E7 |
0.301 |
|
| 2007 |
Wang Z, McPherson PA, Raccor BS, Balachandran R, Zhu G, Day BW, Vogt A, Wipf P. Structure-activity and high-content imaging analyses of novel tubulysins. Chemical Biology & Drug Design. 70: 75-86. PMID 17683369 DOI: 10.1111/J.1747-0285.2007.00541.X |
0.569 |
|
| 2007 |
Wakefield B, Halter RJ, Wipf P. Synthesis of (+/-)-thiohalenaquinone by iterative metalations of thiophene. Organic Letters. 9: 3121-4. PMID 17630756 DOI: 10.1021/Ol071258Y |
0.796 |
|
| 2007 |
Wipf P, Gong H, Janjic JM, Li S, Day BW, Xie W. New opportunities for pregnane X receptor (PXR) targeting in drug development. lessons from Enantio- and species-specific PXR ligands identified from a discovery library of amino acid analogues. Mini Reviews in Medicinal Chemistry. 7: 617-25. PMID 17584160 DOI: 10.2174/138955707780859404 |
0.773 |
|
| 2007 |
Wipf P, Wang Z. Total synthesis of N14-desacetoxytubulysin H. Organic Letters. 9: 1605-7. PMID 17367155 DOI: 10.1021/Ol070415Q |
0.311 |
|
| 2007 |
Jiang J, Kurnikov I, Belikova NA, Xiao J, Zhao Q, Amoscato AA, Braslau R, Studer A, Fink MP, Greenberger JS, Wipf P, Kagan VE. Structural requirements for optimized delivery, inhibition of oxidative stress, and antiapoptotic activity of targeted nitroxides Journal of Pharmacology and Experimental Therapeutics. 320: 1050-1060. PMID 17179468 DOI: 10.1124/Jpet.106.114769 |
0.316 |
|
| 2007 |
Waller DL, Stephenson CR, Wipf P. Spiroketals via oxidative rearrangement of enol ethers. Organic & Biomolecular Chemistry. 5: 58-60. PMID 17164906 DOI: 10.1039/B612992G |
0.613 |
|
| 2007 |
Wipf P, Werner S, Twining LA, Kendall C. HPLC determinations of enantiomeric ratios. Chirality. 19: 5-9. PMID 17089337 DOI: 10.1002/Chir.20331 |
0.731 |
|
| 2007 |
Brisson M, Foster C, Wipf P, Joo B, Tomko RJ, Nguyen T, Lazo JS. Independent mechanistic inhibition of cdc25 phosphatases by a natural product caulibugulone. Molecular Pharmacology. 71: 184-92. PMID 17018577 DOI: 10.1124/Mol.106.028589 |
0.594 |
|
| 2007 |
Wipf P, Furegati M. Synthesis of the 3-aza-[7]-paracyclophane core of haouamine A and B. Organic Letters. 8: 1901-4. PMID 16623580 DOI: 10.1021/Ol060455E |
0.306 |
|
| 2007 |
Wipf P, Graham TH, Xiao J. From natural products to biological tools Pure and Applied Chemistry. 79: 753-761. DOI: 10.1351/Pac200779040753 |
0.659 |
|
| 2007 |
Wipf P, Pierce J. Synthesis of the α-C-Glycoside Analogue of KRN7000 Synfacts. 2007: 0001-0001. DOI: 10.1055/s-2006-955651 |
0.534 |
|
| 2006 |
Wipf P, Pierce JG. Expedient synthesis of the alpha-C-glycoside analogue of the immunostimulant galactosylceramide (KRN7000). Organic Letters. 8: 3375-8. PMID 16836409 DOI: 10.1021/Ol0613057 |
0.603 |
|
| 2006 |
Cossy J, Belotti D, Brisson M, Skoko JJ, Wipf P, Lazo JS. Biological evaluation of newly synthesized quinoline-5,8-quinones as Cdc25B inhibitors Bioorganic and Medicinal Chemistry. 14: 6283-6287. PMID 16782352 DOI: 10.1016/J.Bmc.2006.05.053 |
0.365 |
|
| 2006 |
Wipf P, Walczak MA. Pericyclic cascade reactions of (bicyclo[1.1.0]butylmethyl)amines. Angewandte Chemie (International Ed. in English). 45: 4172-5. PMID 16710876 DOI: 10.1002/Anie.200600723 |
0.484 |
|
| 2006 |
Wipf P, Wang C. Synthesis and Ag(I) complexation studies of tethered westiellamide. Organic Letters. 8: 2381-4. PMID 16706531 DOI: 10.1021/Ol060677C |
0.688 |
|
| 2006 |
Lazo JS, Nunes R, Skoko JJ, Queiroz de Oliveira PE, Vogt A, Wipf P. Novel benzofuran inhibitors of human mitogen-activated protein kinase phosphatase-1. Bioorganic & Medicinal Chemistry. 14: 5643-50. PMID 16698271 DOI: 10.1016/J.Bmc.2006.04.036 |
0.312 |
|
| 2006 |
Levinson N, Hinman R, Patil A, Stephenson CR, Werner S, Woo GH, Xiao J, Wipf P, Lynch KW. Use of transcriptional synergy to augment sensitivity of a splicing reporter assay. Rna (New York, N.Y.). 12: 925-30. PMID 16556940 DOI: 10.1261/Rna.8306 |
0.611 |
|
| 2006 |
Wipf P, Graham TH, Vogt A, Sikorski RP, Ducruet AP, Lazo JS. Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product. Chemical Biology & Drug Design. 67: 66-73. PMID 16492150 DOI: 10.1111/J.1747-0285.2005.00313.X |
0.684 |
|
| 2006 |
Wipf P, Xiao J, Jiang J, Belikova NA, Tyurin VA, Fink MP, Kagan VE. Mitochondrial targeting of selective electron scavengers: synthesis and biological analysis of hemigramicidin-TEMPO conjugates. Journal of the American Chemical Society. 127: 12460-1. PMID 16144372 DOI: 10.1021/Ja053679L |
0.307 |
|
| 2006 |
Sellanes D, Scarone L, Mahler G, Manta E, Baz A, Dematteis S, Saldaña J, Domínguez L, Wipf P, Serra G. Synthesis and evaluation of anthelmintic and cytotoxic properties of bis-1,3-azole analogs of natural products Letters in Drug Design and Discovery. 3: 35-43. DOI: 10.2174/157018006775240962 |
0.322 |
|
| 2006 |
Evans DA, Woerpel KA, Nosse B, Schall A, Shinde Y, Jezek E, Haque MM, Chhor RB, Reiser O, Wipf P, Jayasuriya N. Synthesis of (–)-(S,S)- bis(4-isopropyloxazoline) (4S, 4S')-2,2'-(Propane-2,2-diyl)bis(4-isopropyl-4,5-dihydrooxazole) Organic Syntheses. 83: 97-102. DOI: 10.15227/Orgsyn.083.0097 |
0.393 |
|
| 2006 |
Braunstein MJ, Liu N, Klueppelberg U, Scott C, Behrman S, Tamucin C, Walter P, Wipf P, Brodsky J, Batuman O. Differential Effects of Hsp70 Inhibition within the Tumor and Microenvironment in Multiple Myeloma. Blood. 108: 5070-5070. DOI: 10.1182/Blood.V108.11.5070.5070 |
0.303 |
|
| 2006 |
Wipf P, Grenon M. Toward the total synthesis of lophotoxin - New methodologies and synthetic strategies Canadian Journal of Chemistry. 84: 1226-1241. DOI: 10.1139/V06-073 |
0.383 |
|
| 2006 |
Werner S, Turner DM, Lyon MA, Huryn DM, Wipf P. A focused library of tetrahydropyrimidinone amides via a tandem Biginelli-Ugi multi-component process Synlett. 2334-2338. DOI: 10.1055/S-2006-949648 |
0.347 |
|
| 2006 |
Woo GH, Kim S, Wipf P. π-Allyl palladium approach toward the diazabicyclo[3.2.1]octane core of the naphthyridinomycin alkaloids Tetrahedron. 62: 10507-10517. DOI: 10.1016/J.Tet.2006.06.114 |
0.354 |
|
| 2005 |
Wipf P, Waller DL, Reeves JT. Transition-metal-mediated cascade reactions: the water-accelerated carboalumination-Claisen rearrangement-carbonyl addition reaction. The Journal of Organic Chemistry. 70: 8096-102. PMID 16277333 DOI: 10.1021/Jo051211V |
0.326 |
|
| 2005 |
Wipf P, Lynch SM, Powis G, Birmingham A, Englund EE. Synthesis and biological activity of prodrug inhibitors of the thioredoxin-thioredoxin reductase system. Organic & Biomolecular Chemistry. 3: 3880-2. PMID 16240002 DOI: 10.1039/B510718K |
0.602 |
|
| 2005 |
Nguyen TL, McGrath C, Hermone AR, Burnett JC, Zaharevitz DW, Day BW, Wipf P, Hamel E, Gussio R. A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach. Journal of Medicinal Chemistry. 48: 6107-16. PMID 16162011 DOI: 10.1021/Jm050502T |
0.528 |
|
| 2005 |
Brisson M, Nguyen T, Wipf P, Joo B, Day BW, Skoko JS, Schreiber EM, Foster C, Bansal P, Lazo JS. Redox regulation of Cdc25B by cell-active quinolinediones. Molecular Pharmacology. 68: 1810-20. PMID 16155209 DOI: 10.1124/Mol.105.016360 |
0.697 |
|
| 2005 |
Wipf P, Pierce JG. Synthesis of homoallylic amines by hydrozirconation-imine addition of allenes. Organic Letters. 7: 3537-40. PMID 16048336 DOI: 10.1021/Ol051266J |
0.559 |
|
| 2005 |
Wipf P, Hopkins TD. Total synthesis and structure validation of (+)-bistramide C. Chemical Communications (Cambridge, England). 3421-3. PMID 15997284 DOI: 10.1039/B505100B |
0.35 |
|
| 2005 |
Wipf P, Halter RJ. Chemistry and biology of wortmannin. Organic & Biomolecular Chemistry. 3: 2053-61. PMID 15917886 DOI: 10.1039/B504418A |
0.335 |
|
| 2005 |
Mu Y, Stephenson CR, Kendall C, Saini SP, Toma D, Ren S, Cai H, Strom SC, Day BW, Wipf P, Xie W. A pregnane X receptor agonist with unique species-dependent stereoselectivity and its implications in drug development. Molecular Pharmacology. 68: 403-13. PMID 15872116 DOI: 10.1124/Mol.105.013292 |
0.775 |
|
| 2005 |
Xiao J, Weisblum B, Wipf P. Electrostatic versus steric effects in peptidomimicry: synthesis and secondary structure analysis of gramicidin S analogues with (E)-alkene peptide isosteres. Journal of the American Chemical Society. 127: 5742-3. PMID 15839644 DOI: 10.1021/Ja051002S |
0.302 |
|
| 2005 |
Wipf P, Coleman CM, Janjic JM, Iyer PS, Fodor MD, Shafer YA, Stephenson CR, Kendall C, Day BW. Microwave-assisted "libraries from libraries" approach toward the synthesis of allyl- and C-cyclopropylalkylamides. Journal of Combinatorial Chemistry. 7: 322-30. PMID 15762763 DOI: 10.1021/Cc049842A |
0.806 |
|
| 2005 |
Wipf P, Stephenson CR. Three-component synthesis of alpha,beta-cyclopropyl-gamma-amino acids. Organic Letters. 7: 1137-40. PMID 15760158 DOI: 10.1021/Ol0501525 |
0.625 |
|
| 2005 |
Wipf P, Pierce JG, Zhuang N. Silver(I)-catalyzed addition of zirconocenes to glycal epoxides. A new synthesis of alpha-C-glycosides. Organic Letters. 7: 483-5. PMID 15673270 DOI: 10.1021/Ol0475414 |
0.592 |
|
| 2005 |
Wipf P, Spencer SR. Asymmetric total syntheses of tuberostemonine, didehydrotuberostemonine, and 13-epituberostemonine. Journal of the American Chemical Society. 127: 225-35. PMID 15631472 DOI: 10.1021/Ja044280K |
0.351 |
|
| 2005 |
Wipf P, Graham TH. Synthesis and hetero-Michael addition reactions of 2-alkynyl oxazoles and oxazolines. Organic & Biomolecular Chemistry. 3: 31-5. PMID 15602595 DOI: 10.1039/B413604G |
0.684 |
|
| 2005 |
Janjic JM, Mu Y, Kendall C, Stephenson CR, Balachandran R, Raccor BS, Lu Y, Zhu G, Xie W, Wipf P, Day BW. New antiestrogens from a library screen of homoallylic amides, allylic amides, and C-cyclopropylalkylamides. Bioorganic & Medicinal Chemistry. 13: 157-64. PMID 15582460 DOI: 10.1016/J.Bmc.2004.09.048 |
0.778 |
|
| 2005 |
Wipf P, Kendall C, Stephenson CRJ. Dimethylzinc-Mediated Additions of Alkenylzirconocenes to Aldimines. New Methodologies for Allylic Amine andC-Cyclopropylalkylamine Syntheses [J. Am. Chem.Soc.2003,125, 761−768]. Journal of the American Chemical Society. 127: 9946-9946. DOI: 10.1021/Ja053169R |
0.755 |
|
| 2005 |
Wipf P, Fletcher JM, Scarone L. Microwave-Promoted Oxazole Synthesis: Cyclocondensation Cascade of Oximes and Acyl Chlorides. Cheminform. 36. DOI: 10.1016/J.Tetlet.2005.06.063 |
0.318 |
|
| 2005 |
Wipf P, Werner S, Woo GHC, Stephenson CRJ, Walczak MAA, Coleman CM, Twining LA. Application of divergent multi-component reactions in the synthesis of a library of peptidomimetics based on γ-amino-α,β-cyclopropyl acids Tetrahedron. 61: 11488-11500. DOI: 10.1016/J.Tet.2005.09.016 |
0.374 |
|
| 2005 |
Wipf P, Xiao J, Geib S. Imine Additions of Internal Alkynes for the Synthesis of Trisubstituted (E)-Alkene and Cyclopropane Peptide Isosteres Advanced Synthesis & Catalysis. 347: 1605-1613. DOI: 10.1002/Adsc.200505171 |
0.342 |
|
| 2004 |
Wipf P, Graham TH. Total synthesis of (-)-disorazole C1. Journal of the American Chemical Society. 126: 15346-7. PMID 15563138 DOI: 10.1021/Ja0443068 |
0.698 |
|
| 2004 |
Wipf P, Takada T, Rishel MJ. Synthesis of the tubuvaline-tubuphenylalanine (Tuv-Tup) fragment of tubulysin. Organic Letters. 6: 4057-60. PMID 15496098 DOI: 10.1021/Ol048252I |
0.353 |
|
| 2004 |
Fewell SW, Smith CM, Lyon MA, Dumitrescu TP, Wipf P, Day BW, Brodsky JL. Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity. The Journal of Biological Chemistry. 279: 51131-40. PMID 15448148 DOI: 10.1074/Jbc.M404857200 |
0.541 |
|
| 2004 |
Wipf P, Aoyama Y, Benedum TE. A practical method for oxazole synthesis by cycloisomerization of propargyl amides. Organic Letters. 6: 3593-5. PMID 15387556 DOI: 10.1021/Ol0485058 |
0.368 |
|
| 2004 |
Wipf P, Stephenson CR, Walczak MA. Diversity-oriented synthesis of azaspirocycles. Organic Letters. 6: 3009-12. PMID 15330670 DOI: 10.1021/Ol0487783 |
0.72 |
|
| 2004 |
Wipf P, Joo B, Nguyen T, Lazo JS. Synthesis and biological evaluation of caulibugulones A-E. Organic & Biomolecular Chemistry. 2: 2173-4. PMID 15280951 DOI: 10.1039/B408184F |
0.603 |
|
| 2004 |
Brisson M, Nguyen T, Vogt A, Yalowich J, Giorgianni A, Tobi D, Bahar I, Stephenson CR, Wipf P, Lazo JS. Discovery and characterization of novel small molecule inhibitors of human Cdc25B dual specificity phosphatase. Molecular Pharmacology. 66: 824-33. PMID 15231869 DOI: 10.1124/Mol.104.001784 |
0.649 |
|
| 2004 |
Wipf P, Minion DJ, Halter RJ, Berggren MI, Ho CB, Chiang GG, Kirkpatrick L, Abraham R, Powis G. Synthesis and biological evaluation of synthetic viridins derived from C(20)-heteroalkylation of the steroidal PI-3-kinase inhibitor wortmannin. Organic & Biomolecular Chemistry. 2: 1911-20. PMID 15227545 DOI: 10.1039/B405431H |
0.331 |
|
| 2004 |
Wipf P, Lynch SM, Birmingham A, Tamayo G, Jiménez A, Campos N, Powis G. Natural product based inhibitors of the thioredoxin-thioredoxin reductase system. Organic & Biomolecular Chemistry. 2: 1651-8. PMID 15162219 DOI: 10.1039/B402431A |
0.353 |
|
| 2004 |
Wipf P, Reeves JT, Day BW. Chemistry and biology of curacin A. Current Pharmaceutical Design. 10: 1417-37. PMID 15134491 DOI: 10.2174/1381612043384853 |
0.567 |
|
| 2004 |
Wipf P, Janjic J, Stephenson CR. Microwave-assisted synthesis of allylic amines: considerable rate acceleration in the hydrozirconation-transmetalation-aldimine addition sequence. Organic & Biomolecular Chemistry. 2: 443-5. PMID 14770219 DOI: 10.1039/B316741K |
0.798 |
|
| 2004 |
Serra G, Scarone L, Sellanes D, Manta E, Wipf P. Use of Deoxo-Fluor for Double Cyclization to Bis-thiazolines. Limitations of This Agent for the Synthesis of Oxazolines Heterocycles. 63: 773. DOI: 10.3987/Com-03-9996 |
0.332 |
|
| 2003 |
Wipf P, Stephenson CR, Okumura K. Transition-metal-mediated cascade reactions: C,C-dicyclopropylmethylamines by way of double C,C-sigma-bond insertion into bicyclobutanes. Journal of the American Chemical Society. 125: 14694-5. PMID 14640630 DOI: 10.1002/CHIN.200413056 |
0.623 |
|
| 2003 |
Wipf P, Graham TH. Photoactivated tungsten hexacarbonyl-catalyzed conversion of alkynols to glycals. The Journal of Organic Chemistry. 68: 8798-807. PMID 14604347 DOI: 10.1021/Jo034813S |
0.686 |
|
| 2003 |
Vogt A, Cooley KA, Brisson M, Tarpley MG, Wipf P, Lazo JS. Cell-active dual specificity phosphatase inhibitors identified by high-content screening. Chemistry & Biology. 10: 733-42. PMID 12954332 DOI: 10.1016/S1074-5521(03)00170-4 |
0.304 |
|
| 2003 |
Wipf P, Stephenson CR. Dimethylzinc-mediated addition of alkenylzirconocenes to alpha-keto and alpha-imino esters. Organic Letters. 5: 2449-52. PMID 12841752 DOI: 10.1021/Ol0347141 |
0.627 |
|
| 2003 |
Wipf P, Lynch SM. Synthesis of highly oxygenated dinaphthyl ethers via SNAr reactions promoted by Barton's base. Organic Letters. 5: 1155-8. PMID 12659597 DOI: 10.1021/Ol034286Z |
0.32 |
|
| 2003 |
Wipf P, Kendall C, Stephenson CR. Dimethylzinc-mediated additions of alkenylzirconocenes to aldimines. New methodologies for allylic amine and C-cyclopropylalkylamine syntheses. Journal of the American Chemical Society. 125: 761-8. PMID 12526676 DOI: 10.1021/Ja028092A |
0.796 |
|
| 2003 |
Wipf P, Wang X. Parallel synthesis of oxazolines and thiazolines by tandem condensation-cyclodehydration of carboxylic acids with amino alcohols and aminothiols. Journal of Combinatorial Chemistry. 4: 656-60. PMID 12425611 DOI: 10.1021/Cc020041M |
0.349 |
|
| 2003 |
Wipf P, Pierce JG, Wang X. Investigation of ligand loading and asymmetric amplification in CHAOx-catalyzed asymmetric diethylzinc additions Tetrahedron Asymmetry. 14: 3605-3611. DOI: 10.1016/J.Tetasy.2003.07.022 |
0.566 |
|
| 2003 |
Wipf P, Nunes RL, Ribe S. Water-Accelerated Organometallic Chemistry: Alkyne Carboalumination—Sulfinimine Addition and Asymmetric Synthesis of Allylic Amines. Cheminform. 34. DOI: 10.1002/1522-2675(200210)85:10<3478::Aid-Hlca3478>3.0.Co;2-E |
0.378 |
|
| 2003 |
Weinreb SM, Chase CE, Wipf P, Venkatraman S. 2‐Trimethylsilylethanesulfonyl Chloride (SES‐Cl) Organic Syntheses. 161-161. DOI: 10.1002/0471264180.Os075.20 |
0.543 |
|
| 2002 |
Vogt A, Pestell KE, Day BW, Lazo JS, Wipf P. The antisignaling agent SC-alpha alpha delta 9, 4-(benzyl-(2-[(2,5-diphenyloxazole-4-carbonyl)amino]ethyl)carbamoyl)- 2-decanoylaminobutyric acid, is a structurally unique phospholipid analogue with phospholipase C inhibitory activity. Molecular Cancer Therapeutics. 1: 885-92. PMID 12481409 |
0.467 |
|
| 2002 |
Wipf P, Rector SR, Takahashi H. Total synthesis of (-)-tuberostemonine. Journal of the American Chemical Society. 124: 14848-9. PMID 12475317 DOI: 10.1021/Ja028603T |
0.802 |
|
| 2002 |
Lyon MA, Ducruet AP, Wipf P, Lazo JS. Dual-specificity phosphatases as targets for antineoplastic agents. Nature Reviews. Drug Discovery. 1: 961-76. PMID 12461518 DOI: 10.1038/Nrd963 |
0.301 |
|
| 2002 |
Wipf P, Reeves JT. A formal total synthesis of leucascandrolide A. Chemical Communications (Cambridge, England). 2066-7. PMID 12357781 DOI: 10.1039/B207383H |
0.345 |
|
| 2002 |
Wipf P, Soth MJ. Synthesis of the C(1)-C(18) segment of lophotoxin and pukalide. Control of 2-alkenylfuran (E/Z)-configuration. Organic Letters. 4: 1787-90. PMID 12000299 DOI: 10.1021/Ol025861M |
0.325 |
|
| 2002 |
Wipf P, Reeves JT, Balachandran R, Day BW. Synthesis and biological evaluation of structurally highly modified analogues of the antimitotic natural product curacin A. Journal of Medicinal Chemistry. 45: 1901-17. PMID 11960501 DOI: 10.1021/Jm0105171 |
0.6 |
|
| 2002 |
Wipf P, Kendall C. Novel applications of alkenyl zirconocenes. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 1778-84. PMID 11933105 DOI: 10.1002/1521-3765(20020415)8:8<1778::Aid-Chem1778>3.0.Co;2-H |
0.752 |
|
| 2002 |
Wipf P, Uto Y, Yoshimura S. Total synthesis of a stereoisomer of bistramide C and assignment of configuration of the natural product. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 1670-81. PMID 11933095 DOI: 10.1002/1521-3765(20020402)8:7<1670::Aid-Chem1670>3.0.Co;2-4 |
0.589 |
|
| 2002 |
Wipf P, Wang X. A new ligand scaffold for catalytic asymmetric alkylzinc additions to aldehydes. Organic Letters. 4: 1197-200. PMID 11922817 DOI: 10.1021/Ol025600C |
0.344 |
|
| 2002 |
Lazo JS, Nemoto K, Pestell KE, Cooley K, Southwick EC, Mitchell DA, Furey W, Gussio R, Zaharevitz DW, Joo B, Wipf P. Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors. Molecular Pharmacology. 61: 720-8. PMID 11901209 DOI: 10.1124/Mol.61.4.720 |
0.619 |
|
| 2002 |
Wipf P, Hopkins CR, Phillips EO, Lazo JS. Separation of Cdc25 dual specificity phosphatase inhibition and DNA cleaving activities in a focused library of analogs of the antitumor antibiotic Dnacin Tetrahedron. 58: 6367-6372. DOI: 10.1016/S0040-4020(02)00636-1 |
0.542 |
|
| 2001 |
Lazo JS, Aslan DC, Southwick EC, Cooley KA, Ducruet AP, Joo B, Vogt A, Wipf P. Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25. Journal of Medicinal Chemistry. 44: 4042-9. PMID 11708908 DOI: 10.1021/Jm0102046 |
0.614 |
|
| 2001 |
Wipf P, Hopkins TD, Jung JK, Rodriguez S, Birmingham A, Southwick EC, Lazo JS, Powis G. New inhibitors of the thioredoxin-thioredoxin reductase system based on a naphthoquinone spiroketal natural product lead. Bioorganic & Medicinal Chemistry Letters. 11: 2637-41. PMID 11551767 DOI: 10.1016/S0960-894X(01)00525-X |
0.331 |
|
| 2001 |
Wipf P, Kendall C. Tandem zirconocene homologation-aldimine allylation. Organic Letters. 3: 2773-6. PMID 11506631 DOI: 10.1021/Ol0163880 |
0.753 |
|
| 2001 |
Wipf P, Kendall C, Stephenson CR. Three-component aldimine addition--cyclopropanation. an efficient new methodology for amino cyclopropane synthesis. Journal of the American Chemical Society. 123: 5122-3. PMID 11457353 DOI: 10.1021/Ja0157494 |
0.792 |
|
| 2001 |
Wipf P, Aslan DC. Synthesis of bicyclic ortho esters by epoxy ester rearrangements and study of their ring-opening reactions. The Journal of Organic Chemistry. 66: 337-43. PMID 11429924 DOI: 10.1021/Jo005665Y |
0.359 |
|
| 2001 |
Wipf P, Ribe S. Water-accelerated tandem Claisen rearrangement-catalytic asymmetric carboalumination. Organic Letters. 3: 1503-5. PMID 11388852 DOI: 10.1021/Ol015816Z |
0.323 |
|
| 2001 |
Wipf P, Methot JL. Synthetic studies toward diazonamide A. A novel approach for polyoxazole synthesis. Organic Letters. 3: 1261-4. PMID 11348209 DOI: 10.1021/Ol0157196 |
0.695 |
|
| 2001 |
Wipf P, Graham TH. Synthesis of the C(1')--C(11') segment of leucascandrolide A. The Journal of Organic Chemistry. 66: 3242-5. PMID 11325299 DOI: 10.1021/Jo005787Q |
0.648 |
|
| 2001 |
Wipf P, Hopkins CR. Enantioselective synthesis of the AB-ring system of the antitumor antibiotic tetrazomine. The Journal of Organic Chemistry. 66: 3133-9. PMID 11325279 DOI: 10.1021/Jo015512Q |
0.593 |
|
| 2001 |
Wipf P, Aslan DC, Southwick EC, Lazo JS. Sulfonylated aminothiazoles as new small molecule inhibitors of protein phosphatases. Bioorganic & Medicinal Chemistry Letters. 11: 313-7. PMID 11212099 DOI: 10.1016/S0960-894X(00)00658-2 |
0.329 |
|
| 2001 |
Ribe S, Wipf P. Water-accelerated organic transformations Chemical Communications. 299-307. DOI: 10.1039/B008252J |
0.301 |
|
| 2001 |
Wipf P, Jung J, Rodrı́guez S, Lazo JS. Synthesis and biological evaluation of deoxypreussomerin A and palmarumycin CP1 and related naphthoquinone spiroketals Tetrahedron. 57: 283-296. DOI: 10.1016/S0040-4020(00)00936-4 |
0.354 |
|
| 2001 |
Wipf P, Phillips AJ. Book Review: Transition Metal Reagents and Catalysts. Innovations in Organic Synthesis. By Jiro Tsuji Angewandte Chemie International Edition. 40: 463-463. DOI: 10.1002/1521-3773(20010119)40:2<463::Aid-Anie1111463>3.0.Co;2-J |
0.447 |
|
| 2001 |
Wipf P, Phillips AJ. Buchbesprechung: Transition Metal Reagents and Catalysts. Innovations in Organic Synthesis. Von Jiro Tsuji. Angewandte Chemie. 113: 476-477. DOI: 10.1002/1521-3757(20010119)113:2<476::Aid-Ange476>3.0.Co;2-# |
0.448 |
|
| 2000 |
Wipf P, Methot JL. Total synthesis and stereochemical revision of (+)-aeruginosin 298-A. Organic Letters. 2: 4213-6. PMID 11150202 DOI: 10.1021/Ol006759X |
0.692 |
|
| 2000 |
Wipf P, Jung JK. Formal total synthesis of (+)-diepoxin sigma. The Journal of Organic Chemistry. 65: 6319-37. PMID 11052073 DOI: 10.1021/Jo000684T |
0.385 |
|
| 2000 |
Ducruet AP, Rice RL, Tamura K, Yokokawa F, Yokokawa S, Wipf P, Lazo JS. Identification of new Cdc25 dual specificity phosphatase inhibitors in a targeted small molecule array. Bioorganic & Medicinal Chemistry. 8: 1451-66. PMID 10896122 DOI: 10.1016/S0968-0896(00)00069-9 |
0.357 |
|
| 2000 |
Wipf P, Uto Y. Total synthesis and revision of stereochemistry of the marine metabolite trunkamide A. The Journal of Organic Chemistry. 65: 1037-49. PMID 10814052 DOI: 10.1021/Jo9914566 |
0.609 |
|
| 2000 |
Phillips AJ, Uto Y, Wipf P, Reno MJ, Williams DR. Synthesis of functionalized oxazolines and oxazoles with DAST and Deoxo-Fluor. Organic Letters. 2: 1165-8. PMID 10804580 DOI: 10.1021/Ol005777B |
0.643 |
|
| 2000 |
Wipf P, Aslan DC, Luci DK, Southwick EC, Lazo JS. Synthesis and biological evaluation of a targeted library of protein phosphatase inhibitors. Biotechnology and Bioengineering. 71: 58-70. PMID 10629537 DOI: 10.1002/(Sici)1097-0290(200024)71:1<58::Aid-Bit9>3.0.Co;2-0 |
0.355 |
|
| 2000 |
Wipf P, Reeves JT, Balachandran R, Giuliano KA, Hamel E, Day BW. Synthesis and biological evaluation of a focused mixture library of analogues of the antimitotic marine natural product curacin A Journal of the American Chemical Society. 122: 9391-9395. DOI: 10.1021/Ja002213U |
0.588 |
|
| 2000 |
Wipf P, Miller CP, Grant CM. Synthesis of cyclopeptide alkaloids by cyclooligomerization of dipeptidyl oxazolines Tetrahedron. 56: 9143-9150. DOI: 10.1016/S0040-4020(00)00767-5 |
0.315 |
|
| 1999 |
Wipf P, Hopkins CR. Efficient Synthesis of 1,4-Dihydro-2H-isoquinoline-3,5,8-triones via Cyclobutene Ring Expansion. The Journal of Organic Chemistry. 64: 6881-6887. PMID 11674700 DOI: 10.1021/Jo990089V |
0.559 |
|
| 1999 |
Wipf P, Li W. Formation of Nine-Membered Lactams by Oxidative Ring Expansion of 4-Hydroxyhydroindoles: A Biomimetic Approach toward the Tuberostemonone Ring System? The Journal of Organic Chemistry. 64: 4576-4577. PMID 11674523 DOI: 10.1021/Jo9905064 |
0.437 |
|
| 1999 |
Wipf P, Jeger P, Kim Y. Thiophilic ring-opening and rearrangement reactions of epoxyketone natural products. Bioorganic & Medicinal Chemistry Letters. 8: 351-6. PMID 9871683 DOI: 10.1016/S0960-894X(98)00026-2 |
0.347 |
|
| 1999 |
Wipf P, Tsuchimoto T, Takahashi H. Synthetic applications of ortho esters Pure and Applied Chemistry. 71: 415-421. DOI: 10.1351/Pac199971030415 |
0.334 |
|
| 1999 |
Wipf P, Methot J. Silver(I)-Catalyzed Addition of Zirconocenes to Epoxy Esters: A New Entry to 1,4-Dicarbonyl Compounds and Pyridazinones Organic Letters. 1: 1253-1255. DOI: 10.1021/Ol990924V |
0.376 |
|
| 1999 |
Wipf P, Coish PDG. Total Synthesis of (±)-Nisamycin The Journal of Organic Chemistry. 64: 5053-5061. DOI: 10.1021/Jo990413M |
0.363 |
|
| 1999 |
Wipf P, Weiner WS. Enantioselective Synthesis and Photoracemization Studies of (+)-2-Cyclopropyl-7,8-dimethoxy-2H- chromene-5-carboxylic Acid Methyl Ester, an Advanced Intermediate of a Dihydrofolate Reductase Inhibitor The Journal of Organic Chemistry. 64: 5321-5324. DOI: 10.1021/Jo990352S |
0.323 |
|
| 1999 |
Wipf P, Uto Y. Total synthesis of the putative structure of the marine metabolite trunkamide A Tetrahedron Letters. 40: 5165-5169. DOI: 10.1016/S0040-4039(99)00957-0 |
0.574 |
|
| 1999 |
Wipf P, Reeves JT. Synthesis and applications of a highly fluorous alkoxy ethyl ether protective group Tetrahedron Letters. 40: 5139-5142. DOI: 10.1016/S0040-4039(99)00883-7 |
0.316 |
|
| 1998 |
Wipf P, Rahman LT, Rector SR. A General Strategy for Five-Membered Heterocycle Synthesis by Cycloelimination of Alkynyl Ketones, Amides, and Thioamides. The Journal of Organic Chemistry. 63: 7132-7133. PMID 11672349 DOI: 10.1021/Jo981542Q |
0.801 |
|
| 1998 |
Wipf P, Takahashi H, Zhuang N. Kinetic vs. thermodynamic control in hydrozirconation reactions Pure and Applied Chemistry. 70: 1077-1082. DOI: 10.1351/Pac199870051077 |
0.332 |
|
| 1998 |
Wipf P, Yokokawa F. Synthetic studies toward diazonamide A. Preparation of the benzofuranone-indolyloxazole fragment Tetrahedron Letters. 39: 2223-2226. DOI: 10.1016/S0040-4039(98)00231-7 |
0.319 |
|
| 1998 |
Wipf P, Hayes GB. Synthesis of oxazines and thiazines by cyclodehydration of hydroxy amides and thioamides Tetrahedron. 54: 6987-6998. DOI: 10.1016/S0040-4020(98)00341-X |
0.347 |
|
| 1997 |
Studer A, Jeger P, Wipf P, Curran DP. Fluorous Synthesis: Fluorous Protocols for the Ugi and Biginelli Multicomponent Condensations. The Journal of Organic Chemistry. 62: 2917-2924. PMID 11671655 DOI: 10.1021/Jo970095W |
0.333 |
|
| 1997 |
Rice RL, Rusnak JM, Yokokawa F, Yokokawa S, Messner DJ, Boynton AL, Wipf P, Lazo JS. A targeted library of small-molecule, tyrosine, and dual-specificity phosphatase inhibitors derived from a rational core design and random side chain variation. Biochemistry. 36: 15965-74. PMID 9398331 DOI: 10.1021/Bi971338H |
0.358 |
|
| 1997 |
Wipf P, Cunningham A, Rice RL, Lazo JS. Combinatorial synthesis and biological evaluation of library of small-molecule Ser/Thr-protein phosphatase inhibitors. Bioorganic & Medicinal Chemistry. 5: 165-77. PMID 9043668 DOI: 10.1016/S0968-0896(96)00199-X |
0.354 |
|
| 1997 |
Studer A, Hadida S, Ferritto R, Kim SY, Jeger P, Wipf P, Curran DP. Fluorous synthesis: a fluorous-phase strategy for improving separation efficiency in organic synthesis. Science (New York, N.Y.). 275: 823-6. PMID 9012347 DOI: 10.1126/Science.275.5301.823 |
0.313 |
|
| 1997 |
Wipf P, Xu W, Takahashi H, Jahn H, Coish PDG. Synthetic applications of organozirconocenes Pure and Applied Chemistry. 69: 639-644. DOI: 10.1351/Pac199769030639 |
0.312 |
|
| 1997 |
Wipf P, Coish PD. Organozirconocene-mediated polyene synthesis: Preparation of asukamycin and manumycin a side chains Tetrahedron Letters. 38: 5073-5076. DOI: 10.1016/S0040-4039(97)01129-5 |
0.33 |
|
| 1997 |
Wipf P, Xu W, Kim H, Takahashi H. Zirconocene-catalyzed epoxy ester - ortho ester rearrangement: A new method for the protection of polyfunctionalized carboxylic acids and the asymmetric synthesis of ortho esters Tetrahedron. 53: 16575-16596. DOI: 10.1016/S0040-4020(97)01038-7 |
0.339 |
|
| 1997 |
Wipf P, Jung J. Weitreichende elektrostatische Effekte in der Synthese: dipolkontrollierte nucleophile Addition an ein Naphthochinonacetal — Modelluntersuchungen zur Darstellung von Diepoxin σ Angewandte Chemie. 109: 785-788. DOI: 10.1002/Ange.19971090723 |
0.327 |
|
| 1996 |
Wipf P, Xu W. Total Synthesis of the Antimitotic Marine Natural Product (+)-Curacin A. The Journal of Organic Chemistry. 61: 6556-6562. PMID 11667520 DOI: 10.1021/Jo960845M |
0.364 |
|
| 1996 |
Wipf P, Li W, Adeyeye CM, Rusnak JM, Lazo JS. Synthesis of chemoreversible prodrugs of ara-C with variable time-release profiles. Biological evaluation of their apoptotic activity. Bioorganic & Medicinal Chemistry. 4: 1585-96. PMID 8931928 DOI: 10.1016/0968-0896(96)00153-8 |
0.471 |
|
| 1996 |
Wipf P, Venkatraman S. A new thiazole synthesis by cyclocondensation of thioamides and alkynyl(aryl)iodonium reagents Journal of Organic Chemistry. 61: 8004-8005. DOI: 10.1021/Jo961681C |
0.365 |
|
| 1996 |
Wipf P, Venkatraman S. Total synthesis of (-)-muscoride A Journal of Organic Chemistry. 61: 6517-6522. DOI: 10.1021/Jo960891M |
0.373 |
|
| 1996 |
Wipf P, Fritch PC. Total Synthesis and Assignment of Configuration of Lissoclinamide 7 Journal of the American Chemical Society. 118: 12358-12367. DOI: 10.1021/Ja962859F |
0.37 |
|
| 1996 |
Wipf P, Venkatraman S. An improved protocol for azole synthesis with PEG-supported Burgess reagent Tetrahedron Letters. 37: 4659-4662. DOI: 10.1016/0040-4039(96)00918-5 |
0.324 |
|
| 1996 |
Goldstein DM, Wipf P. Studies toward the synthesis of Stemona alkaloids; a short synthesis of the tricyclic core of tuberostemonines Tetrahedron Letters. 37: 739-742. DOI: 10.1016/0040-4039(95)02302-X |
0.348 |
|
| 1995 |
Wipf P, Venkatraman S. Total synthesis of (-)-thiangazole and structurally related polyazoles Journal of Organic Chemistry. 60: 7224-7229. DOI: 10.1021/Jo00127A030 |
0.376 |
|
| 1995 |
Wipf P, Kim Y, Goldstein DM. Asymmetric total synthesis of the Stemona alkaloid (-)-stenine Journal of the American Chemical Society. 117: 11106-11112. DOI: 10.1021/Ja00150A010 |
0.345 |
|
| 1995 |
Wipf P, Lim S. Total Synthesis of the Enantiomer of the Antiviral Marine Natural Product Hennoxazole A Journal of the American Chemical Society. 117: 558-559. DOI: 10.1021/Ja00106A075 |
0.312 |
|
| 1995 |
Wipf P, Xu W. Zirconocene-catalyzed cationic Diels-Alder reactions Tetrahedron. 51: 4551-4562. DOI: 10.1016/0040-4020(94)01140-U |
0.337 |
|
| 1994 |
Wipf P, Fritch PC. SN2'-Reactions of Peptide Aziridines. A Cuprate-Based Approach to (E)-Alkene Isosteres The Journal of Organic Chemistry. 59: 4875-4886. DOI: 10.1021/Jo00096A033 |
0.316 |
|
| 1994 |
Wipf P, Kim Y. Synthesis of the Antitumor Antibiotic LL-C10037.alpha. The Journal of Organic Chemistry. 59: 3518-3519. DOI: 10.1021/Jo00092A004 |
0.336 |
|
| 1993 |
Wipf P. Transmetalation Reactions in Organocopper Chemistry Synthesis. 1993: 537-557. DOI: 10.1055/S-1993-25900 |
0.336 |
|
| 1993 |
Wipf P, Lim S. Addition of organochromium reagents to aldehydes, ketones and enones: a low-temperature version of the Nozaki–Hiyama reaction Journal of the Chemical Society, Chemical Communications. 1654-1656. DOI: 10.1039/C39930001654 |
0.312 |
|
| 1993 |
Wipf P, Kim Y, Fritch PC. Total synthesis and structure assignment of the antitumor antibiotic aranorosin The Journal of Organic Chemistry. 58: 7195-7203. DOI: 10.1021/Jo00077A050 |
0.343 |
|
| 1993 |
Wipf P, Xu W. Synthesis and reactivity of dioxycarbenium ions from epoxy esters and cationic zirconium complexes The Journal of Organic Chemistry. 58: 5880-5882. DOI: 10.1021/Jo00074A006 |
0.306 |
|
| 1993 |
Wipf P, Miller CP. A new synthesis of highly functionalized oxazoles The Journal of Organic Chemistry. 58: 3604-3606. DOI: 10.1021/Jo00066A004 |
0.305 |
|
| 1993 |
Wipf P, Venkatraman S. Transmetalation reactions of organosamarium reagents. Chlorosilane-accelerated copper-catalyzed conjugate additions The Journal of Organic Chemistry. 58: 3455-3459. DOI: 10.1021/Jo00064A040 |
0.33 |
|
| 1993 |
Wipf P, Kim Y. Stereoselective synthesis of the functionalized spirocyclic core of aranorosin The Journal of Organic Chemistry. 58: 1649-1650. DOI: 10.1021/Jo00059A004 |
0.335 |
|
| 1992 |
Wipf P, Xu W. Transmetalation Reactions of Organozirconocenes: A General, Selective, and Facile Synthesis of Ketones from Acid Chlorides Synlett. 1992: 718-721. DOI: 10.1055/S-1992-21466 |
0.341 |
|
| 1992 |
Wipf P, Smitrovich JH, Moon CW. Transmetalation reactions of alkenylalanes: copper-catalyzed conjugate addition to enones The Journal of Organic Chemistry. 57: 3178-3186. DOI: 10.1021/Jo00037A040 |
0.372 |
|
| 1992 |
Wipf P, Miller CP. Total synthesis of westiellamide Journal of the American Chemical Society. 114: 10975-10977. DOI: 10.1021/Ja00053A052 |
0.341 |
|
| 1992 |
Wipf P, Miller CP. A short, stereospecific synthesis of dihydrooxazoles from serine and threonine derivatives Tetrahedron Letters. 33: 907-910. DOI: 10.1016/S0040-4039(00)91572-7 |
0.347 |
|
| 1992 |
Wipf P, Kim Y. Studies on the synthesis of Stemona alkaloids; stereoselective preparation of the hydroindole ring system by oxidative cyclization of tyrosine Tetrahedron Letters. 33: 5477-5480. DOI: 10.1016/S0040-4039(00)61121-8 |
0.355 |
|
| 1991 |
Ireland RE, Wipf P, Xiang JN. Stereochemical control in the ester enolate Claisen rearrangement. 2. Chairlike vs boatlike transition-state selection Journal of Organic Chemistry. 56: 3572-3582. DOI: 10.1021/Jo00011A023 |
0.537 |
|
| 1991 |
Ireland RE, Wipf P, Armstrong JD. Stereochemical control in the ester enolate Claisen rearrangement. 1. Stereoselectivity in silyl ketene acetal formation Journal of Organic Chemistry. 56: 650-657. DOI: 10.1021/Jo00002A030 |
0.554 |
|
| 1991 |
Wipf P, Li W, Sekhar V. Synthesis of chemoreversible prodrugs of ARA-C Bioorganic & Medicinal Chemistry Letters. 1: 745-750. DOI: 10.1016/S0960-894X(01)81061-1 |
0.509 |
|
| 1991 |
Wipf P, Xu W, Smitrovich JH, Lehmann R, Venanzi LM. Copper-catalyzed conjugate additions of organozirconocenes. Synthetic and mechanistic studies. Tetrahedron. 50: 1935-1954. DOI: 10.1016/S0040-4020(01)85058-4 |
0.313 |
|
| 1990 |
Ireland RE, Wipf P, Roper TD. Use of a masked aldol unit in the synthesis of the right side of FK-506 Journal of Organic Chemistry. 55: 2284-2285. DOI: 10.1021/Jo00295A009 |
0.776 |
|
| 1990 |
Ireland RE, Wipf P. Carboalumination of 1-alkynes and in situ transmetalation to higher order cyanocuprates. Stereospecific synthesis of tri- and disubstituted olefins by conjugate addition to enones Journal of Organic Chemistry. 55: 1425-1426. DOI: 10.1021/Jo00292A009 |
0.58 |
|
| 1990 |
Ireland RE, Wipf P, Miltz W, Vanasse B. Methodology for the enantioselective synthesis of aldols and other 1,3-dioxygenated systems Journal of Organic Chemistry. 55: 1423-1424. DOI: 10.1021/Jo00292A008 |
0.585 |
|
| 1990 |
Wipf P, Heimgartner H. Synthesis of Peptides Containing ?,?-Disubstituted ?-Amino Acids by the Azirine/Oxazolone Method: The (12-20)-Nonapeptide of the Ionophore Alamethicin Helvetica Chimica Acta. 73: 13-24. DOI: 10.1002/Hlca.19900730103 |
0.379 |
|
| 1990 |
IRELAND RE, WIPF P, MILTZ W, VANASSE B. ChemInform Abstract: Methodology for the Enantioselective Synthesis of Aldols and Other 1,3-Dioxygenated Systems. Cheminform. 21. DOI: 10.1002/chin.199033189 |
0.504 |
|
| 1990 |
IRELAND RE, WIPF P. ChemInform Abstract: Carboalumination of 1-Alkynes and in situ Transmetalation to Higher Order Cyanocuprates. Stereospecific Synthesis of Tri- and Disubstituted Olefins by Conjugate Addition to Enones. Cheminform. 21. DOI: 10.1002/chin.199033063 |
0.537 |
|
| 1990 |
WIPF P, HEIMGARTNER H. ChemInform Abstract: Synthesis of Peptides Containing α,α-Disubstituted α-Amino Acids by the Azirine/Oxazolone Method. The (12-20)-Nonapeptide of the Ionophore Alamethicin. Cheminform. 21. DOI: 10.1002/chin.199017287 |
0.345 |
|
| 1989 |
Ireland RE, Wipf P. Studies directed towards the total synthesis of FK-506 preparation of a C(1) to C(15) segment Tetrahedron Letters. 30: 919-922. DOI: 10.1016/S0040-4039(00)95278-X |
0.492 |
|
| 1989 |
Sahebi M, Wipf P, Heimgartner H. 3-Amino-2H-azirines in the synthesis of peptides: Tetrahedron. 45: 2999-3010. DOI: 10.1016/S0040-4020(01)80127-7 |
0.455 |
|
| 1989 |
Jenny C, Wipf P, Heimgartner H. Radikalische Cyclisierungen von Alkenyl-substituierten 4,5-Dihydro-1,3-thiazol-5-thiolen Helvetica Chimica Acta. 72: 838-846. DOI: 10.1002/Hlca.19890720425 |
0.489 |
|
| 1989 |
SAHEBI M, WIPF P, HEIMGARTNER H. ChemInform Abstract: 3-Amino-2H-azirines in the Synthesis of Peptides: Tetrapeptides with α,α-Disubstituted α-Amino Acids. Cheminform. 20. DOI: 10.1002/chin.198938336 |
0.347 |
|
| 1989 |
JENNY C, WIPF P, HEIMGARTNER H. ChemInform Abstract: Radical Cyclizations of Alkenyl-Substituted 4,5-Dihydro-1,3-thiazole-5-thiols. Cheminform. 20. DOI: 10.1002/chin.198937205 |
0.394 |
|
| 1988 |
Wipf P, Prevo R, Bieri JH, Germain G, Heimgartner H. (Benzylthio)- und (Arylthio)-substituierte Nitril-ylide: Thermische Erzeugung und Reaktionen Helvetica Chimica Acta. 71: 1177-1190. DOI: 10.1002/Hlca.19880710529 |
0.387 |
|
| 1988 |
Wipf P, Kunz RW, Prewo R, Heimgartner H. Konformationsanalysen von Modell-Tripeptiden: Der Einfluss von ?,?-disubstituierten ?-Aminos�uren auf die Sekund�rstruktur. Teil II. R�ntgenstrukturanalyse und Konformationsenergie-Berechnungen Helvetica Chimica Acta. 71: 268-273. DOI: 10.1002/Hlca.19880710130 |
0.324 |
|
| 1988 |
Wipf P, Heimgartner H. Konformationsanalysen von Modell-Tripeptiden: Der Einfluss von ?,?-disubstituierten ?-Aminos�uren auf die Sekund�rstruktur. Teil I. NMR- und CD-Untersuchungen Helvetica Chimica Acta. 71: 258-267. DOI: 10.1002/Hlca.19880710129 |
0.337 |
|
| 1988 |
Wipf P, Heimgartner H. Anwendung der Azirin/Oxazolon-Methode in der Peptid-Chemie: Synthese von Modell-Tripeptiden Helvetica Chimica Acta. 71: 140-154. DOI: 10.1002/Hlca.19880710118 |
0.381 |
|
| 1988 |
WIPF P, PREWO R, BIERI JH, GERMAIN G, HEIMGARTNER H. ChemInform Abstract: Thermal Generation and Reactions of (Benzylthio)- and (Arylthio)-Substituted Nitrile Ylides. Cheminform. 19. DOI: 10.1002/chin.198848068 |
0.371 |
|
| 1988 |
WIPF P, HEIMGARTNER H. ChemInform Abstract: The Azirine/Oxazolone Method in Peptide Chemistry: Synthesis of Tripeptide Models. Cheminform. 19. DOI: 10.1002/chin.198817319 |
0.364 |
|
| 1988 |
WIPF P, KUNZ RW, PREWO R, HEIMGARTNER H. ChemInform Abstract: Conformational Analysis of Tripeptide Models: Influence of α,α-Disubstituted α-Amino Acids on the Secondary Structure. Part 2. X-Ray Analysis and Conformational Energy Calculations Cheminform. 19. DOI: 10.1002/chin.198817056 |
0.327 |
|
| 1988 |
WIPF P, HEIMGARTNER H. ChemInform Abstract: Conformational Analysis of Tripeptide Models: Influence of α,α-Disubstituted α-Amino Acids on the Secondary Structure. Part 1. NMR and CD Investigations. Cheminform. 19. DOI: 10.1002/chin.198817055 |
0.33 |
|
| 1987 |
Wipf P, Heimgartner H. Selektive Amidspaltung bei Peptiden mit alpha,alpha-disubstituierten alpha-Aminosäuren Helvetica Chimica Acta. 70: 354-368. DOI: 10.5167/Uzh-95992 |
0.451 |
|
| 1987 |
Wipf P, Prewo R, Jost HB, Heimgartner H, Nastopoulos V, Germain G. Synthese von 4-Benzylthio- und 4-(Arylthio)-1,3-oxazol-5(2H)-onen Helvetica Chimica Acta. 70: 1380-1388. DOI: 10.1002/Hlca.19870700518 |
0.406 |
|
| 1987 |
Wipf P, Jenny C, Heimgartner H. 2,4-Bis(4-methylpheylthio)-1,3,2?5,4?5-dithiadiphosphetan-2,4-dithion: Ein neues Reagens zur Schwefelung vonN,N-disubstituierten Amiden Helvetica Chimica Acta. 70: 1001-1011. DOI: 10.1002/Hlca.19870700412 |
0.363 |
|
| 1987 |
Wipf P, Heimgartner H. Bildung tricyclischer Thietan-Derivate durch intramolekulare(2+2)-Cycloaddition Helvetica Chimica Acta. 70: 992-994. DOI: 10.1002/Hlca.19870700409 |
0.368 |
|
| 1987 |
Wipf P, Heimgartner H. Selektive Amidspaltung bei Peptiden mit ?,?-disubstituierten ?-Aminos�uren Helvetica Chimica Acta. 70: 354-368. DOI: 10.1002/Hlca.19870700213 |
0.382 |
|
| 1987 |
WIPF P, PREWO R, BIERI JH, HEIMGARTNER H, NASTOPOULOS V, GERMAIN G. ChemInform Abstract: Synthesis of 4-(Benzylthio)- and 4-(Arylthio)-1,3-oxazole-5(2H)-ones. Cheminform. 18. DOI: 10.1002/chin.198746194 |
0.385 |
|
| 1987 |
WIPF P, JENNY C, HEIMGARTNER H. ChemInform Abstract: 2,4-Bis(4-methylphenylthio)-1,3,2λ5,4λ5-dithiadiphosphetane-2,4-d# ithione: A New Reagent for Thiation of N,N-Disubstituted Amides. Cheminform. 18. DOI: 10.1002/chin.198743098 |
0.34 |
|
| 1987 |
WIPF P, HEIMGARTNER H. ChemInform Abstract: Formation of Tricyclic Thietane Derivatives via Intramolecular (2 + 2) Cycloaddition. Cheminform. 18. DOI: 10.1002/chin.198742161 |
0.416 |
|
| 1987 |
WIPF P, HEIMGARTNER H. ChemInform Abstract: Selective Amide Cleavage in Peptides Containing α,α-Disubstituted α-Amino Acids. Cheminform. 18. DOI: 10.1002/chin.198728312 |
0.335 |
|
| 1987 |
JENNY C, WIPF P, HEIMGARTNER H. ChemInform Abstract: Carbophilic Additions of Organocuprates to 1,3-Thiazole-5(4H)-thiones. Cheminform. 18. DOI: 10.1002/chin.198716207 |
0.328 |
|
| 1986 |
Jenny C, Wipf P, Heimgartner H. Carbophile Additionen von Organocupraten mit 1,3-Thiazol-5(4H)-thionen Helvetica Chimica Acta. 69: 1837-1843. DOI: 10.1002/Hlca.19860690809 |
0.358 |
|
| 1986 |
Wipf P, Heimgartner H. Kupplung von Peptiden mit C-terminalen ?,?-disubstituierten ? - Aminos�urenvia Oxazol-5(4H)-one Helvetica Chimica Acta. 69: 1153-1162. DOI: 10.1002/Hlca.19860690524 |
0.391 |
|
| 1986 |
WIPF P, HEIMGARTNER H. ChemInform Abstract: Peptide-Bond Formation with C-Terminal α,α-Disubstituted α-Amino Acids via Intermediate Oxazol-5(4H)-ones. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198646320 |
0.348 |
|
| 1985 |
WIPF P, HEIMGARTNER H. ChemInform Abstract: SYNTHESIS OF 4-ARYLTHIO-3-OXAZOLIN-5-ONES Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198513162 |
0.435 |
|
| 1985 |
WIPF P, HEIMGARTNER H. ChemInform Abstract: ARYLTHIO-SUBSTITUTED NITRILE YLIDES BY THERMOLYSIS OF 4-(ARYLTHIO)-3-OXAZOLIN-5-ONES Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198508132 |
0.405 |
|
| 1984 |
Wipf P, Heimgartner H. Synthese von 4-arylthio-3-oxazolin-5-onen Tetrahedron Letters. 25: 5127-5128. DOI: 10.1016/S0040-4039(01)81541-0 |
0.437 |
|
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