| Year |
Citation |
Score |
| 2021 |
Piyadasa H, Hemshekhar M, Osawa N, Lloyd D, Altieri A, Basu S, Krokhin OV, Halayko AJ, Mookherjee N. Disrupting Tryptophan in the Central Hydrophobic Region Selectively Mitigates Immunomodulatory Activities of the Innate Defence Regulator Peptide IDR-1002. Journal of Medicinal Chemistry. PMID 33974425 DOI: 10.1021/acs.jmedchem.0c02065 |
0.321 |
|
| 2020 |
Hemshekhar M, Piyadasa H, Mostafa D, Chow LNY, Halayko AJ, Mookherjee N. Cathelicidin and Calprotectin Are Disparately Altered in Murine Models of Inflammatory Arthritis and Airway Inflammation. Frontiers in Immunology. 11: 1932. PMID 32973796 DOI: 10.3389/Fimmu.2020.01932 |
0.342 |
|
| 2020 |
Piyadasa H, Lloyd D, Lee AHY, Altieri A, Hemshekhar M, Osawa N, Basu S, Blimkie T, Falsafi R, Halayko AJ, Hancock REW, Mookherjee N. Characterization of immune responses and the lung transcriptome in a murine model of IL-33 challenge. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165950. PMID 32841733 DOI: 10.1016/J.Bbadis.2020.165950 |
0.32 |
|
| 2020 |
Mookherjee N, Anderson MA, Haagsman HP, Davidson DJ. Antimicrobial host defence peptides: functions and clinical potential. Nature Reviews. Drug Discovery. PMID 32107480 DOI: 10.1038/S41573-019-0058-8 |
0.366 |
|
| 2019 |
Semple C, Choi KG, Kroeker A, Denechezhe L, Orr P, Mookherjee N, Larcombe L. Polymorphisms in the P2X7 receptor, and differential expression of Toll-like receptor-mediated cytokines and defensins, in a Canadian Indigenous group. Scientific Reports. 9: 14204. PMID 31578370 DOI: 10.1038/S41598-019-50596-0 |
0.375 |
|
| 2019 |
van der Does AM, Hiemstra PS, Mookherjee N. Antimicrobial Host Defence Peptides: Immunomodulatory Functions and Translational Prospects. Advances in Experimental Medicine and Biology. 1117: 149-171. PMID 30980358 DOI: 10.1007/978-981-13-3588-4_10 |
0.411 |
|
| 2018 |
Hemshekhar M, Choi KG, Mookherjee N. Host Defense Peptide LL-37-Mediated Chemoattractant Properties, but Not Anti-Inflammatory Cytokine IL-1RA Production, Is Selectively Controlled by Cdc42 Rho GTPase G Protein-Coupled Receptors and JNK Mitogen-Activated Protein Kinase. Frontiers in Immunology. 9: 1871. PMID 30158931 DOI: 10.3389/Fimmu.2018.01871 |
0.401 |
|
| 2018 |
Altieri A, Piyadasa H, Recksiedler B, Spicer V, Mookherjee N. Cytokines IL-17, TNF and IFN-γ Alter the Expression of Antimicrobial Peptides and Proteins Disparately: A Targeted Proteomics Analysis using SOMAscan Technology. Vaccines. 6. PMID 30087279 DOI: 10.3390/Vaccines6030051 |
0.413 |
|
| 2018 |
Piyadasa H, Hemshekhar M, Altieri A, Basu S, van der Does AM, Halayko AJ, Hiemstra PS, Mookherjee N. Immunomodulatory innate defence regulator (IDR) peptide alleviates airway inflammation and hyper-responsiveness. Thorax. PMID 29853649 DOI: 10.1136/Thoraxjnl-2017-210739 |
0.39 |
|
| 2018 |
Mookherjee N, Piyadasa H, Ryu MH, Rider CF, Ezzati P, Spicer V, Carlsten C. Inhaled diesel exhaust alters the allergen-induced bronchial secretome in humans. The European Respiratory Journal. 51. PMID 29371381 DOI: 10.1183/13993003.01385-2017 |
0.306 |
|
| 2018 |
Altieri A, Piyadasa H, Spicer V, Halayko AJ, Mookherjee N. Proteomic profiling to define synergistic responses mediated by IL-17 and TNFa in the lungs European Respiratory Journal. DOI: 10.1183/13993003.Congress-2018.Pa1118 |
0.305 |
|
| 2018 |
Piyadasa H, Hemshekhar M, Altieri A, Basu S, Does AMVD, Halayko AJ, Hiemstra PS, Mookherjee N. Activity of an innate defence regulator peptide to alleviate airway inflammation is mitigated by disruption of its central hydrophobic region European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Pa1104 |
0.407 |
|
| 2017 |
Piyadasa H, Hemshekhar M, Carlsten C, Mookherjee N. Inhaled Diesel Exhaust Decreases Antimicrobial Peptides Alpha-defensin and S100A7 in Human Bronchial Secretion. American Journal of Respiratory and Critical Care Medicine. PMID 29244524 DOI: 10.1164/Rccm.201708-1714Le |
0.311 |
|
| 2016 |
Hemshekhar M, Anaparti V, Mookherjee N. Functions of Cationic Host Defense Peptides in Immunity. Pharmaceuticals (Basel, Switzerland). 9. PMID 27384571 DOI: 10.3390/Ph9030040 |
0.392 |
|
| 2016 |
Piyadasa H, Altieri A, Basu S, Schwartz J, Halayko AJ, Mookherjee N. Biosignature for airway inflammation in a house dust mite-challenged murine model of allergic asthma. Biology Open. PMID 26740570 DOI: 10.1242/Bio.014464 |
0.332 |
|
| 2016 |
Mookherjee N, Ezzati P, Spicer V, Carlsten C. LATE-BREAKING ABSTRACT: Inhaled diesel exhaust alters immune response proteins in the bronchial secretome in humans European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa1213 |
0.31 |
|
| 2015 |
Guchhait G, Altieri A, Gorityala B, Yang X, Findlay B, Zhanel GG, Mookherjee N, Schweizer F. Amphiphilic tobramycins with immunomodulatory properties. Angewandte Chemie (International Ed. in English). 54: 6278-82. PMID 25847672 DOI: 10.1002/Anie.201500598 |
0.378 |
|
| 2014 |
Domalaon R, Yang X, O'Neil J, Zhanel GG, Mookherjee N, Schweizer F. Structure-activity relationships in ultrashort cationic lipopeptides: the effects of amino acid ring constraint on antibacterial activity. Amino Acids. 46: 2517-30. PMID 25069750 DOI: 10.1007/S00726-014-1806-Z |
0.319 |
|
| 2014 |
Choi KY, Napper S, Mookherjee N. Human cathelicidin LL-37 and its derivative IG-19 regulate interleukin-32-induced inflammation. Immunology. 143: 68-80. PMID 24666281 DOI: 10.1111/Imm.12291 |
0.42 |
|
| 2014 |
Chow LN, Choi KY, Piyadasa H, Bossert M, Uzonna J, Klonisch T, Mookherjee N. Human cathelicidin LL-37-derived peptide IG-19 confers protection in a murine model of collagen-induced arthritis. Molecular Immunology. 57: 86-92. PMID 24091294 DOI: 10.1016/J.Molimm.2013.08.011 |
0.397 |
|
| 2014 |
Hitchon C, Mookherjee N, Larcombe L, Newkirk M, Meng X, Buttar G, Kelekis-Cholakis A, Schroth R, El-Gabalawy H. AB0042 Human Host Defense Peptide Cathelicidin (LL37) Serum Levels Are Increased in Anti-Cyclical Citrullinated Peptide Positive Patients with Recent Onset Inflammatory Arthritis Annals of the Rheumatic Diseases. 73: 818.1-818. DOI: 10.1136/Annrheumdis-2014-Eular.3978 |
0.356 |
|
| 2013 |
Findlay B, Mookherjee N, Schweizer F. Ultrashort cationic lipopeptides and lipopeptoids selectively induce cytokine production in macrophages. Plos One. 8: e54280. PMID 23390497 DOI: 10.1371/Journal.Pone.0054280 |
0.312 |
|
| 2013 |
Mookherjee N. Modulation of immune-mediated inflammation by cationic innate defence regulator peptides Journal of Clinical & Cellular Immunology. DOI: 10.4172/2155-9899.S1.011 |
0.303 |
|
| 2013 |
Hitchon C, Larcombe L, Newkirk M, Mookherjee N, Peschken C, El-Gabalawy H. AB0268 Vitamin D receptor polymorphisms in early inflammatory arthritis are associated with clinical outcomes and IGM responses to common pathogens but not baseline disease activity Annals of the Rheumatic Diseases. 71: 653.1-653. DOI: 10.1136/Annrheumdis-2012-Eular.268 |
0.315 |
|
| 2012 |
Larcombe L, Orr P, Turner-Brannen E, Slivinski CR, Nickerson PW, Mookherjee N. Effect of vitamin D supplementation on Mycobacterium tuberculosis-induced innate immune responses in a Canadian Dené First Nations cohort. Plos One. 7: e40692. PMID 22866178 DOI: 10.1371/Journal.Pone.0040692 |
0.339 |
|
| 2012 |
Choi KY, Chow LN, Mookherjee N. Cationic host defence peptides: multifaceted role in immune modulation and inflammation. Journal of Innate Immunity. 4: 361-70. PMID 22739631 DOI: 10.1159/000336630 |
0.396 |
|
| 2012 |
Choi KY, Mookherjee N. Multiple immune-modulatory functions of cathelicidin host defense peptides. Frontiers in Immunology. 3: 149. PMID 22701455 DOI: 10.3389/Fimmu.2012.00149 |
0.404 |
|
| 2012 |
Choi KY, Lippert DN, Ezzatti P, Mookherjee N. Defining TNF-α and IL-1β induced nascent proteins: combining bio-orthogonal non-canonical amino acid tagging and proteomics. Journal of Immunological Methods. 382: 189-95. PMID 22698787 DOI: 10.1016/J.Jim.2012.06.003 |
0.328 |
|
| 2011 |
Turner-Brannen E, Choi KY, Lippert DN, Cortens JP, Hancock RE, El-Gabalawy H, Mookherjee N. Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts. Arthritis Research & Therapy. 13: R129. PMID 21835002 DOI: 10.1186/Ar3440 |
0.433 |
|
| 2011 |
Turner-Brannen E, Choi KY, Arsenault R, El-Gabalawy H, Napper S, Mookherjee N. Inflammatory cytokines IL-32 and IL-17 have common signaling intermediates despite differential dependence on TNF-receptor 1. Journal of Immunology (Baltimore, Md. : 1950). 186: 7127-35. PMID 21602493 DOI: 10.4049/Jimmunol.1002306 |
0.326 |
|
| 2009 |
Mookherjee N, Lippert DN, Hamill P, Falsafi R, Nijnik A, Kindrachuk J, Pistolic J, Gardy J, Miri P, Naseer M, Foster LJ, Hancock RE. Intracellular receptor for human host defense peptide LL-37 in monocytes. Journal of Immunology (Baltimore, Md. : 1950). 183: 2688-96. PMID 19605696 DOI: 10.4049/Jimmunol.0802586 |
0.437 |
|
| 2009 |
Mader JS, Mookherjee N, Hancock RE, Bleackley RC. The human host defense peptide LL-37 induces apoptosis in a calpain- and apoptosis-inducing factor-dependent manner involving Bax activity. Molecular Cancer Research : McR. 7: 689-702. PMID 19435812 DOI: 10.1158/1541-7786.Mcr-08-0274 |
0.303 |
|
| 2009 |
Mookherjee N, Hamill P, Gardy J, Blimkie D, Falsafi R, Chikatamarla A, Arenillas DJ, Doria S, Kollmann TR, Hancock RE. Systems biology evaluation of immune responses induced by human host defence peptide LL-37 in mononuclear cells. Molecular Biosystems. 5: 483-96. PMID 19381363 DOI: 10.1039/B813787K |
0.349 |
|
| 2009 |
Turner-Brannen E, Choi K(, Mookherjee N. A comparative investigation of cellular responses induced by cytokines IL-17 and IL-32 in human monocytic cells and fibroblasts-like synovial cells Cytokine. 48: 95. DOI: 10.1016/J.Cyto.2009.07.397 |
0.324 |
|
| 2007 |
Yu J, Mookherjee N, Wee K, Bowdish DM, Pistolic J, Li Y, Rehaume L, Hancock RE. Host defense peptide LL-37, in synergy with inflammatory mediator IL-1beta, augments immune responses by multiple pathways. Journal of Immunology (Baltimore, Md. : 1950). 179: 7684-91. PMID 18025214 DOI: 10.4049/Jimmunol.179.11.7684 |
0.401 |
|
| 2007 |
Mookherjee N, Rehaume LM, Hancock RE. Cathelicidins and functional analogues as antisepsis molecules. Expert Opinion On Therapeutic Targets. 11: 993-1004. PMID 17665972 DOI: 10.1517/14728222.11.8.993 |
0.384 |
|
| 2007 |
Scott MG, Dullaghan E, Mookherjee N, Glavas N, Waldbrook M, Thompson A, Wang A, Lee K, Doria S, Hamill P, Yu JJ, Li Y, Donini O, Guarna MM, Finlay BB, et al. An anti-infective peptide that selectively modulates the innate immune response. Nature Biotechnology. 25: 465-72. PMID 17384586 DOI: 10.1038/Nbt1288 |
0.406 |
|
| 2007 |
Mookherjee N, Hancock RE. Cationic host defence peptides: innate immune regulatory peptides as a novel approach for treating infections. Cellular and Molecular Life Sciences : Cmls. 64: 922-33. PMID 17310278 DOI: 10.1007/S00018-007-6475-6 |
0.389 |
|
| 2006 |
Mookherjee N, Wilson HL, Doria S, Popowych Y, Falsafi R, Yu JJ, Li Y, Veatch S, Roche FM, Brown KL, Brinkman FS, Hokamp K, Potter A, Babiuk LA, Griebel PJ, et al. Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide. Journal of Leukocyte Biology. 80: 1563-74. PMID 16943385 DOI: 10.1189/Jlb.0106048 |
0.399 |
|
| 2006 |
Hancock RE, Brown KL, Mookherjee N. Host defence peptides from invertebrates--emerging antimicrobial strategies. Immunobiology. 211: 315-22. PMID 16697922 DOI: 10.1016/J.Imbio.2005.10.017 |
0.378 |
|
| 2006 |
Mookherjee N, Brown KL, Bowdish DM, Doria S, Falsafi R, Hokamp K, Roche FM, Mu R, Doho GH, Pistolic J, Powers JP, Bryan J, Brinkman FS, Hancock RE. Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37. Journal of Immunology (Baltimore, Md. : 1950). 176: 2455-64. PMID 16456005 DOI: 10.4049/Jimmunol.176.4.2455 |
0.403 |
|
| 2005 |
Griebel PJ, Brownlie R, Manuja A, Nichani A, Mookherjee N, Popowych Y, Mutwiri G, Hecker R, Babiuk LA. Bovine toll-like receptor 9: a comparative analysis of molecular structure, function and expression. Veterinary Immunology and Immunopathology. 108: 11-6. PMID 16098606 DOI: 10.1016/J.Vetimm.2005.07.012 |
0.359 |
|
| 2002 |
Mookherjee N, Pearson TW. Trypanosoma simiae and Trypanosoma congolense: surface glycoconjugates of procyclic forms-the same coats on different hangers? Experimental Parasitology. 100: 257-68. PMID 12128053 DOI: 10.1016/S0014-4894(02)00023-1 |
0.528 |
|
| 2001 |
Mookherjee N, Pearson TW. Surface molecules of procyclic forms of Trypanosoma simiae and Trypanosoma congolense, members of the subgenus Nannomonas, share immunodominant carbohydrate epitopes. Molecular and Biochemical Parasitology. 118: 123-6. PMID 11704280 DOI: 10.1016/S0166-6851(01)00358-9 |
0.513 |
|
| 1999 |
Bütikofer P, Vassella E, Ruepp S, Boschung M, Civenni G, Seebeck T, Hemphill A, Mookherjee N, Pearson TW, Roditi I. Phosphorylation of a major GPI-anchored surface protein of Trypanosoma brucei during transport to the plasma membrane. Journal of Cell Science. 112: 1785-95. PMID 10318770 |
0.479 |
|
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