Joseph M. Tager - Publications

Affiliations: 
University of Amsterdam, Amsterdam, Netherlands 
Area:
biochemistry

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
1994 Tager JM, Aerts JM, van den Bogert C, Wanders RJ. Signals on proteins, intracellular targeting and inborn errors of organellar metabolism. Journal of Inherited Metabolic Disease. 17: 459-69. PMID 7967496 DOI: 10.1007/BF00711361  0.475
1993 van Weely S, Brandsma M, Strijland A, Tager JM, Aerts JM. Demonstration of the existence of a second, non-lysosomal glucocerebrosidase that is not deficient in Gaucher disease. Biochimica Et Biophysica Acta. 1181: 55-62. PMID 8457606 DOI: 10.1016/0925-4439(93)90090-N  0.621
1993 van Weely S, van den Berg M, Barranger JA, Sa Miranda MC, Tager JM, Aerts JM. Role of pH in determining the cell-type-specific residual activity of glucocerebrosidase in type 1 Gaucher disease. The Journal of Clinical Investigation. 91: 1167-75. PMID 8450045 DOI: 10.1172/Jci116276  0.713
1993 Aerts JM, Van Weely S, Boot R, Hollak CE, Tager JM. Pathogenesis of lysosomal storage disorders as illustrated by Gaucher disease. Journal of Inherited Metabolic Disease. 16: 288-91. PMID 8411983 DOI: 10.1007/BF00710267  0.479
1993 Middelkoop E, Wiemer EA, Schoenmaker DE, Strijland A, Tager JM. Topology of catalase assembly in human skin fibroblasts. Biochimica Et Biophysica Acta. 1220: 15-20. PMID 8268239 DOI: 10.1016/0167-4889(93)90091-3  0.406
1992 Wiemer EA, Ofman R, Middelkoop E, de Boer M, Wanders RJ, Tager JM. Production and characterisation of monoclonal antibodies against native and disassembled human catalase. Journal of Immunological Methods. 151: 165-75. PMID 1629607 DOI: 10.1016/0022-1759(92)90115-A  0.333
1992 Heikoop JC, Wanders RJ, Strijland A, Purvis R, Schutgens RB, Tager JM. Genetic and biochemical heterogeneity in patients with the rhizomelic form of chondrodysplasia punctata--a complementation study. Human Genetics. 89: 439-44. PMID 1618493 DOI: 10.1007/Bf00194319  0.347
1992 Kwekkeboom J, de Groot C, Tager JM. Efficient electric field-induced generation of hybridomas from human B lymphocytes without prior activation in vitro. Human Antibodies and Hybridomas. 3: 48-53. PMID 1576322 DOI: 10.3233/Hab-1992-3108  0.302
1992 Wanders RJ, van Roermund CW, Brul S, Schutgens RB, Tager JM. Bifunctional enzyme deficiency: identification of a new type of peroxisomal disorder in a patient with an impairment in peroxisomal beta-oxidation of unknown aetiology by means of complementation analysis. Journal of Inherited Metabolic Disease. 15: 385-8. PMID 1357231 DOI: 10.1007/Bf02435983  0.518
1992 Lombardo MC, van der Zwaan JW, Brul S, Tager JM. A procedure for selecting mammalian cells with an impairment in oxidative phosphorylation. Biochimica Et Biophysica Acta. 1138: 275-81. PMID 1314097 DOI: 10.1016/0925-4439(92)90004-7  0.522
1991 Lageweg W, Wanders RJ, Tager JM. Long-chain-acyl-CoA synthetase and very-long-chain-acyl-CoA synthetase activities in peroxisomes and microsomes from rat liver. An enzymological study. European Journal of Biochemistry / Febs. 196: 519-23. PMID 2007410 DOI: 10.1111/J.1432-1033.1991.Tb15844.X  0.322
1991 Middelkoop E, Strijland A, Tager JM. Does aminotriazole inhibit import of catalase into peroxisomes by retarding unfolding? Febs Letters. 279: 79-82. PMID 1995347 DOI: 10.1016/0014-5793(91)80255-2  0.332
1991 Van Weely S, Van Leeuwen MB, Jansen IDC, De Bruijn MAC, Brouwer-Kelder EM, Schram A, Sa Miranda MC, Barranger JA, Petersen EM, Goldblatt J, Stotz H, Schwarzmann G, Sandhoff K, Svennerholm L, Erikson A, ... Tager JM, et al. Clinical phenotype of Gaucher disease in relation to properties of mutant glucocerebrosidase in cultured fibroblasts Bba - Molecular Basis of Disease. 1096: 301-311. PMID 1829642 DOI: 10.1016/0925-4439(91)90066-I  0.651
1991 Lageweg W, Steen I, Tager JM, Wanders RJ. A fluorimetric assay for acyl-CoA synthetase activities. Analytical Biochemistry. 197: 384-8. PMID 1785692 DOI: 10.1016/0003-2697(91)90408-L  0.322
1991 Wiemer EA, Out M, Schelen A, Wanders RJ, Schutgens RB, Van den Bosch H, Tager JM. Phenotypic heterogeneity in cultured skin fibroblasts from patients with disorders of peroxisome biogenesis belonging to the same complementation group. Biochimica Et Biophysica Acta. 1097: 232-7. PMID 1718439 DOI: 10.1016/0925-4439(91)90041-7  0.334
1991 Ohashi T, Hong CM, Weiler S, Tomich JM, Aerts JM, Tager JM, Barranger JA. Characterization of human glucocerebrosidase from different mutant alleles. The Journal of Biological Chemistry. 266: 3661-7. PMID 1704891  0.698
1991 van Roermund CW, Brul S, Tager JM, Schutgens RB, Wanders RJ. Acyl-CoA oxidase, peroxisomal thiolase and dihydroxyacetone phosphate acyltransferase: aberrant subcellular localization in Zellweger syndrome. Journal of Inherited Metabolic Disease. 14: 152-64. PMID 1679469 DOI: 10.1007/Bf01800588  0.54
1991 Wolvetang EJ, Tager JM, Wanders RJ. Factors influencing the latency of the peroxisomal enzyme dihydroxyacetone-phosphate acyltransferase (DHAP-AT) in permeabilized human skin fibroblasts. Biochimica Et Biophysica Acta. 1095: 122-6. PMID 1657193 DOI: 10.1016/0167-4889(91)90074-8  0.383
1990 Hardeman D, Zomer HW, Schutgens RB, Tager JM, van den Bosch H. Effect of peroxisome proliferation on ether phospholipid biosynthesizing enzymes in rat liver. The International Journal of Biochemistry. 22: 1413-8. PMID 2276415 DOI: 10.1016/0020-711X(90)90231-Q  0.399
1990 Sa Miranda MC, Aerts JM, Pinto R, Fontes A, de Lacerda LW, van Weely S, Barranger J, Tager JM. Activity of glucocerebrosidase in extracts of different cell types from type 1 Gaucher disease patients. Clinical Genetics. 38: 218-27. PMID 2225530 DOI: 10.1111/J.1399-0004.1990.Tb03573.X  0.722
1990 Aerts JM, Sa Miranda MC, Brouwer-Kelder EM, Van Weely S, Barranger JA, Tager JM. Conditions affecting the activity of glucocerebrosidase purified from spleens of control subjects and patients with type 1 Gaucher disease. Biochimica Et Biophysica Acta. 1041: 55-63. PMID 2223847 DOI: 10.1016/0167-4838(90)90122-V  0.73
1990 Aerts JM, Donker-Koopman WE, Brul S, Van Weely S, Sa Miranda MC, Barranger JA, Tager JM, Schram AW. Comparative study on glucocerebrosidase in spleens from patients with Gaucher disease. The Biochemical Journal. 269: 93-100. PMID 2198026 DOI: 10.1042/Bj2690093  0.76
1990 Tager JM, Brul S, Wiemer EA, Strijland A, Van Driel R, Schutgens RB, Van den Bosch H, Wanders RJ, Westerveld A. Genetic relationship between the Zellweger syndrome and other peroxisomal disorders characterized by an impairment in the assembly of peroxisomes. Progress in Clinical and Biological Research. 321: 545-58. PMID 2183242  0.651
1990 Wolvetang EJ, Wanders RJ, Schutgens RB, Berden JA, Tager JM. Properties of the ATPase activity associated with peroxisome-enriched fractions from rat liver: comparison with mitochondrial F1F0-ATPase. Biochimica Et Biophysica Acta. 1035: 6-11. PMID 2166576 DOI: 10.1016/0304-4165(90)90166-T  0.367
1990 Van Weely S, Aerts JM, Van Leeuwen MB, Heikoop JC, Donker-Koopman WE, Barranger JA, Tager JM, Schram AW. Function of oligosaccharide modification in glucocerebrosidase, a membrane-associated lysosomal hydrolase. European Journal of Biochemistry / Febs. 191: 669-77. PMID 2143986 DOI: 10.1111/J.1432-1033.1990.Tb19173.X  0.731
1990 BRUL S, WIEMER E, WESTERVELD A, STRIJLAND A, WANDERS R, TAGER J, SLATER E. A simple selection procedure for cells deficient in peroxisomes Cell Biology International Reports. 14: 64. DOI: 10.1016/0309-1651(90)90363-4  0.641
1990 Tager JM, Brul S, Wiemer EAC, Heikoop JC, Middelkoop E, Bout A, Westerveld A, Wanders RJA. Peroxisomal disorders: An updating Adrenoleukodystrophy and Other Peroxisomal Disorders. Clinical, Biochemical, Genetic and Therapeutic Aspects: Proceedings of the International Workshop. Ics898. 3-15.  0.584
1989 De Boer M, Ossendorp FA, Van Duijn G, Ten Voorde GH, Tager JM. Optimal conditions for the generation of monoclonal antibodies using primary immunisation of mouse splenocytes in vitro under serum-free conditions. Journal of Immunological Methods. 121: 253-60. PMID 2760468 DOI: 10.1016/0022-1759(89)90168-3  0.305
1989 Bout A, Hoovers JM, Bakker E, Mannens MM, Geurts van Kessel A, Westerveld A, Tager JM, Benne R. Assignment of the gene coding for human peroxisomal 3-oxoacyl-CoA thiolase (ACAA) to chromosome region 3p22----p23. Cytogenetics and Cell Genetics. 52: 147-50. PMID 2630187 DOI: 10.1159/000132865  0.508
1989 Al BJ, Tiffany CW, Gomes de Mesquita DS, Moser HW, Tager JM, Schram AW. Properties of acid ceramidase from human spleen. Biochimica Et Biophysica Acta. 1004: 245-51. PMID 2526656 DOI: 10.1016/0005-2760(89)90274-9  0.367
1989 Wanders RJ, Wiemer EA, Brul S, Schutgens RB, van den Bosch H, Tager JM. Prenatal diagnosis of Zellweger syndrome by direct visualization of peroxisomes in chorionic villus fibroblasts by immunofluorescence microscopy. Journal of Inherited Metabolic Disease. 12: 301-4. PMID 2512431 DOI: 10.1007/Bf03335405  0.495
1989 Klumperman J, Fransen J, Boekesteijn J, Hauri H, Tager J, Ginsel L. Secretion of precursors of lysosomal enzymes by Caco-2 cells Ultramicroscopy. 31: 472. DOI: 10.1016/0304-3991(89)90387-2  0.39
1989 Klumperman J, Boekesteijn J, Fransen J, Hauei H, Tager J, Ginsel L. Secretion of the lysosomal enzyme alpha-glucosidase by caco-2 cells occurs mainly from the apical side Ultramicroscopy. 27: 210. DOI: 10.1016/0304-3991(89)90130-7  0.361
1988 Aerts JM, Heikoop J, van Weely S, Donker-Koopman WE, Barranger JA, Tager JM, Schram AW. Characterization of glucocerebrosidase in peripheral blood cells and cultured blastoid cells. Experimental Cell Research. 177: 391-8. PMID 3391250 DOI: 10.1016/0014-4827(88)90472-7  0.699
1988 Brul S, Wiemer EA, Westerveld A, Strijland A, Wanders RJ, Schram AW, Heymans HS, Schutgens RB, Van den Bosch H, Tager JM. Kinetics of the assembly of peroxisomes after fusion of complementary cell lines from patients with the cerebro-hepato-renal (Zellweger) syndrome and related disorders. Biochemical and Biophysical Research Communications. 152: 1083-9. PMID 3377768 DOI: 10.1016/S0006-291X(88)80395-4  0.631
1988 Aerts JM, Schram AW, Strijland A, van Weely S, Jonsson LM, Tager JM, Sorrell SH, Ginns EI, Barranger JA, Murray GJ. Glucocerebrosidase, a lysosomal enzyme that does not undergo oligosaccharide phosphorylation. Biochimica Et Biophysica Acta. 964: 303-8. PMID 3349099 DOI: 10.1016/0304-4165(88)90030-X  0.729
1988 Willemsen R, van Dongen JM, Aerts JM, Schram AW, Tager JM, Goudsmit R, Reuser AJ. An immunoelectron microscopic study of glucocerebrosidase in type 1 Gaucher's disease spleen. Ultrastructural Pathology. 12: 471-8. PMID 3194992 DOI: 10.3109/01913128809032232  0.578
1988 Sa Miranda MC, Aerts JM, Pinto RA, Magalhaes JA, Barranger JA, Tager JM, Schram AW. Heterogeneity in human acid beta-glucosidase revealed by cellulose-acetate electrophoresis. Biochimica Et Biophysica Acta. 965: 163-8. PMID 3130106 DOI: 10.1016/0304-4165(88)90052-9  0.676
1988 Brul S, Westerveld A, Strijland A, Wanders RJ, Schram AW, Heymans HS, Schutgens RB, van den Bosch H, Tager JM. Genetic heterogeneity in the cerebrohepatorenal (Zellweger) syndrome and other inherited disorders with a generalized impairment of peroxisomal functions. A study using complementation analysis. The Journal of Clinical Investigation. 81: 1710-5. PMID 2454948 DOI: 10.1172/Jci113510  0.648
1988 Klumperman J, Fransen J, Boekesteijn-Dorsman J, Oude Elferink R, Tager J, Ginsel L. Intracellular transport of the lysosomal enzyme α-clucosidase in the human epithelial cell line Caco-2 Ultramicroscopy. 24: 440. DOI: 10.1016/0304-3991(88)90178-7  0.342
1988 Ginsel L, Fransen J, Klumperman J, Hauri H, Tager J. The use of immunoelectron microscopy to detect pathways for the transport of brush-border and lysosomal enzymes in human enterocytes Ultramicroscopy. 24: 433. DOI: 10.1016/0304-3991(88)90160-X  0.321
1988 Fransen J, Oude Elferink R, Cambier P, Klumperman J, Tager J, Ginsel L. Demonstration of the lysosomal enzyme α-glucosidase in the brush border of human intestinal epithelial cells Ultramicroscopy. 24: 432. DOI: 10.1016/0304-3991(88)90157-X  0.352
1987 Aerts JM, Donker-Koopman WE, van Laar C, Brul S, Murray GJ, Wenger DA, Barranger JA, Tager JM, Schram AW. Relationship between the two immunologically distinguishable forms of glucocerebrosidase in tissue extracts. European Journal of Biochemistry / Febs. 163: 583-9. PMID 3830174 DOI: 10.1111/J.1432-1033.1987.Tb10907.X  0.763
1987 Wanders RJ, Strijland A, van Roermund CW, van den Bosch H, Schutgens RB, Tager JM, Schram AW. Catalase in cultured skin fibroblasts from patients with the cerebro-hepato-renal (Zellweger) syndrome: normal maturation in peroxisome-deficient cells. Biochimica Et Biophysica Acta. 923: 478-82. PMID 3828388 DOI: 10.1016/0304-4165(87)90057-2  0.395
1987 Willemsen R, von Dongen JM, Ginns EI, Sips HJ, Schram AW, Tager JM, Barranger JA, Reuser AJJ. Ultrastructural localization of glucocerebrosidase in cultured Gaucher's disease fibroblasts by immunocytochemistry Journal of Neurology. 234: 44-51. PMID 3819786 DOI: 10.1007/Bf00314009  0.59
1987 de Vries AC, Schram AW, van den Berg M, Tager JM, Batenburg JJ, van Golde LM. An improved procedure for the isolation of lamellar bodies from human lung. Lamellar bodies free of lysosomes contain a spectrum of lysosomal-type hydrolases. Biochimica Et Biophysica Acta. 922: 259-69. PMID 3689811 DOI: 10.1016/0005-2760(87)90048-8  0.362
1987 Wanders RJ, Barth PG, van Roermund CW, Ofman R, Wolterman R, Schutgens RB, Tager JM, van den Bosch H, Bolhuis PA. Peroxisomes and peroxisomal functions in muscle. Studies with muscle cells from controls and a patient with the cerebro-hepato-renal (Zellweger) syndrome. Experimental Cell Research. 170: 147-52. PMID 3569428 DOI: 10.1016/0014-4827(87)90123-6  0.309
1987 Jonsson LM, Murray GJ, Sorrell SH, Strijland A, Aerts JF, Ginns EI, Barranger JA, Tager JM, Schram AW. Biosynthesis and maturation of glucocerebrosidase in Gaucher fibroblasts. European Journal of Biochemistry / Febs. 164: 171-9. PMID 3549301 DOI: 10.1111/J.1432-1033.1987.Tb11008.X  0.714
1987 Mutsaers JH, Van Halbeek H, Vliegenthart JF, Tager JM, Reuser AJ, Kroos M, Galjaard H. Determination of the structure of the carbohydrate chains of acid alpha-glucosidase from human placenta. Biochimica Et Biophysica Acta. 911: 244-51. PMID 3542049 DOI: 10.1016/0167-4838(87)90014-8  0.313
1987 Quintern LE, Weitz G, Nehrkorn H, Tager JM, Schram AW, Sandhoff K. Acid sphingomyelinase from human urine: purification and characterization. Biochimica Et Biophysica Acta. 922: 323-36. PMID 2825797 DOI: 10.1016/0005-2760(87)90055-5  0.405
1987 Klumperman J, Fransen J, Dorsman J, Hauri H, Oude Elferink R, Tager J, Ginsel L. Immunoelectronmicroscopical localization of a lysosomal and a brush-border enzyme in Caco-2 cells Ultramicroscopy. 21: 197-198. DOI: 10.1016/0304-3991(87)90120-3  0.369
1987 Fransen J, Klumperman J, Ginsen L, Oude Elferink R, Hilgers J, Tager J. Immunocytochemical demonstration of a precursor form of the lysosomal enzyme α-glucosidase in the brush border of human enterocytes Ultramicroscopy. 21: 191. DOI: 10.1016/0304-3991(87)90106-9  0.352
1986 Aerts JMFG, Donker-Koopman WE, Koot M, Murray GJ, Barranger JA, Tager JM, Schram AW. Comparison of the properties of a soluble form of glucocerebrosidase from human urine with those of the membrane-associated tissue enzyme Bba - Biomembranes. 863: 63-70. PMID 3778913 DOI: 10.1016/0005-2736(86)90387-1  0.707
1986 Aerts JMFG, Donker-Koopman WE, Murray GJ, Barranger JA, Tager JM, Schram A. A procedure for the rapid purification in high yield of human glucocerebrosidase using immunoaffinity chromatography with monoclonal antibodies Analytical Biochemistry. 154: 655-663. PMID 3728974 DOI: 10.1016/0003-2697(86)90043-6  0.713
1986 Oude Elferink RPJ, van Doorn-Van Wakeren J, Hendriks T, Strijland A, Tager JM. Transport and processing of endocytosed lysosomal α-glucosidase in cultured human skin fibroblasts European Journal of Biochemistry. 158: 339-344. PMID 3525157 DOI: 10.1111/J.1432-1033.1986.Tb09756.X  0.38
1986 Ossendorp FA, De Boer M, J.M. Al B, Hilgers J, Bruning PF, Tager JM. Production of murine monoclonal antibodies against human thyroglobulin using an in vitro immunization procedure in serum-free medium Journal of Immunological Methods. 91: 257-264. PMID 3488350 DOI: 10.1016/0022-1759(86)90487-4  0.313
1986 Aerts JM, Brul S, Donker-Koopman WE, van Weely S, Murray GJ, Barranger JA, Tager JM, Schram AW. Efficient routing of glucocerebrosidase to lysosomes requires complex oligosaccharide chain formation. Biochemical and Biophysical Research Communications. 141: 452-8. PMID 2948505 DOI: 10.1016/S0006-291X(86)80194-2  0.757
1986 Aerts JMFG, Donker-Koopman WE, Koot M, Barranger JA, Tager JM, Schram A. Deficient activity of glucocerebrosidase in urine from patients with type 1 Gaucher disease Clinica Chimica Acta. 158: 155-163. PMID 2943536 DOI: 10.1016/0009-8981(86)90231-7  0.721
1986 Schram AW, Strijland A, Hashimoto T, Wanders RJ, Schutgens RB, van den Bosch H, Tager JM. Biosynthesis and maturation of peroxisomal β-oxidation enzymes in fibroblasts in relation to the Zellweger syndrome and infantile Refsum disease Proceedings of the National Academy of Sciences of the United States of America. 83: 6156-6158. PMID 2426710 DOI: 10.1073/pnas.83.16.6156  0.311
1985 Wanders RJA, van Weringh G, Schrakamp G, Tager JM, van den Bosch H, Schutgens RBH. Deficiency of acyl-CoA: dihydroxyacetone phosphate acyltransferase in thrombocytes of Zellweger patients: a simple postnatal diagnostic test Clinica Chimica Acta. 151: 217-221. PMID 4053381 DOI: 10.1016/0009-8981(85)90083-X  0.42
1985 Aerts JMFG, Donker-Koopman WE, van Der Vliet MK, Jonsson LM, Ginns EI, Murray GJ, Barranger JA, Tager JM, Schram AW. The occurrence of two immunologically distinguishable β-glucocerebrosidases in human spleen European Journal of Biochemistry. 150: 565-574. PMID 4018098 DOI: 10.1111/J.1432-1033.1985.Tb09058.X  0.708
1985 Tager JM, Ten Harmsen Van Der Beek WA, Wanders RJA, Hashimoto T, Heymans HSA, Van Den Bosch H, Schutgens RBH, Schram A. Peroxisomal β-oxidation enzyme proteins in the Zellweger syndrome Biochemical and Biophysical Research Communications. 126: 1269-1275. PMID 3977916 DOI: 10.1016/0006-291X(85)90322-5  0.392
1985 de Vries ACJ, Schram A, Tager JM, Batenburg JJ, van Golde LMG. A specific acid α-glucosidase in lamellar bodies of the human lung Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 837: 230-238. PMID 3933564 DOI: 10.1016/0005-2760(85)90046-3  0.308
1985 Oude Elferink RPJ, van Doorn-Van Wakeren J, Strijland A, Reuser AJ, Tager JM. Biosynthesis and intracellular transport of α-glucosidase and cathepsin D in normal and mutant human fibroblasts European Journal of Biochemistry. 153: 55-63. PMID 3905406 DOI: 10.1111/J.1432-1033.1985.Tb09266.X  0.374
1985 Hakvoort TBM, Veyron P, Muilerman HG, Van Dijk W, Tager JM. Identification of denatured enzyme proteins in sodium dodecyl sulfate polyacrylamide gels Biochemical Medicine. 33: 327-333. PMID 3893424 DOI: 10.1016/0006-2944(85)90007-9  0.407
1985 Driessen M, Weitz G, Brouwer-Kelder EM, Donker-Koopman WE, Bastiaannet J, Sandhoff K, Barranger JA, Tager JM, Schram A. The effect of detergents on immunoprecipitability of lysosomal sphingomyelinase Bba - General Subjects. 841: 97-102. PMID 2990569 DOI: 10.1016/0304-4165(85)90278-8  0.595
1985 Weitz G, Driessen M, Brouwer-Kelder EM, Sandhoff K, Barranger JA, Tager JM, Schram A. Soluble sphingomyelinase from human urine as antigen for obtaining anti-sphingomyelinase antibodies Bba - General Subjects. 838: 92-97. PMID 2981569 DOI: 10.1016/0304-4165(85)90254-5  0.619
1985 van Dongen JM, Willemsen R, Ginns EI, Sips HJ, Tager JM, Barranger JA, Reuser AJ. The subcellular localization of soluble and membrane-bound lysosomal enzymes in I-cell fibroblasts: A comparative immunocytochemical study European Journal of Cell Biology. 39: 179-189. PMID 2935398  0.589
1985 Haussinger D, Soboll S, Meijer AJ, Gerok W, Tager JM, Sies H. Role of plasma membrane transport in hepatic glutamine metabolism European Journal of Biochemistry. 152: 597-603. PMID 2865140 DOI: 10.1111/J.1432-1033.1985.Tb09237.X  0.303
1985 Tager JM. Biosynthesis and deficiency of lysosomal enzymes Trends in Biochemical Sciences. 10: 324-326. DOI: 10.1016/0968-0004(85)90174-4  0.326
1984 Tager JM, Jonsson LVM, Aerts JMFG, Elferink RP, Schram AW, Erickson AH, Barranger JA. Metabolic consequences of genetic defects in lysosomes Biochemical Society Transactions. 12: 902-905. PMID 6530036 DOI: 10.1042/Bst0120902  0.649
1984 Oude Elferink RP, Strijland A, Surya I, Brouwer-Kelder EM, Kroos M, Hilkens J, Hilgers J, Reuser AJ, Tager JM. Use of a monoclonal antibody to distinguish between precursor and mature forms of human lysosomal alpha-glucosidase. European Journal of Biochemistry. 139: 497-502. PMID 6365554 DOI: 10.1111/J.1432-1033.1984.Tb08033.X  0.315
1984 Oude Elferink RP, Brouwer-Kelder EM, Surya I, Strijland A, Kroos M, Reuser AJ, Tager JM. Isolation and characterization of a precursor form of lysosomal alpha-glucosidase from human urine. European Journal of Biochemistry. 139: 489-95. PMID 6365553 DOI: 10.1111/J.1432-1033.1984.Tb08032.X  0.322
1984 Schram AW, Dreissen M, Bastiaannet J, Donker-Koopman WE, Brouwer-Kelder EM, Weitz G, Barranger JA, Sandhoff K, Tager JM. Immunological studies on lysosomal sphingomyelinase: Identification of a 28 000-Da component deficient in urine from patients with Niemann-Pick disease types A and B Bioscience Reports. 4: 1051-1057. PMID 6099155 DOI: 10.1007/Bf01116698  0.595
1984 Schram AW, Weitz G, Driessen M, Brouwer-Kelder EM, Sandhoff K, Barranger JA, Tager JM. Immunological properties of urinary sphingomyelinase Biochemical Society Transactions. 12: 1027-1028. DOI: 10.1042/Bst0121027  0.528
1983 Barneveld RA, Keijzer W, Tegelaers FP, Ginns EI, Geurts van Kessel A, Brady RO, Barranger JA, Tager JM, Galjaard H, Westerveld A, Reuser AJ. Assignment of the gene coding for human beta-glucocerebrosidase to the region q21-q31 of chromosome 1 using monoclonal antibodies. Human Genetics. 64: 227-31. PMID 6885065 DOI: 10.1007/Bf00279398  0.688
1983 Ginns EI, Tegelaers FP, Barneveld R, Galjaard H, Reuser AJ, Brady RO, Tager JM, Barranger JA. Determination of Gaucher's disease phenotypes with monoclonal antibody. Clinica Chimica Acta; International Journal of Clinical Chemistry. 131: 283-7. PMID 6883722 DOI: 10.1016/0009-8981(83)90097-9  0.603
1983 Gankema HS, Groen AK, Wanders RJA, Tager JM. Measurement of binding of adenine nucleotides and phosphate to cytosolic proteins in permeabilized rat-liver cells European Journal of Biochemistry. 131: 447-451. PMID 6832160 DOI: 10.1111/J.1432-1033.1983.Tb07283.X  0.303
1983 Ginns EI, Erickson A, Tegelaers FP, Barneveld R, Reuser AJ, Brady RO, Tager JM, Barranger JA. Isozymes of beta-glucosidase: determination of Gaucher's disease phenotypes. Isozymes. 11: 83-93. PMID 6417048  0.53
1983 Duszynski J, Groen AK, Wanders RJ, Vervoorn RC, Tager JM. Quantification of the role of the adenine nucleotide translocator in the control of mitochondrial respiration in isolated rat-liver cells. Febs Letters. 146: 262-6. PMID 6291990 DOI: 10.1016/0014-5793(82)80931-9  0.302
1983 Barneveld RA, Tegelaers FP, Ginns EI, Visser P, Laanen EA, Brady RO, Galjaard H, Barranger JA, Reuser AJ, Tager JM. Monoclonal antibodies against human beta-glucocerebrosidase. European Journal of Biochemistry / Febs. 134: 585-9. PMID 6192991 DOI: 10.1111/J.1432-1033.1983.Tb07606.X  0.617
1982 Gankema HS, Laanen E, Groen AK, Tager JM. Characterization of isolated rat-liver cells made permeable with filipin. European Journal of Biochemistry. 119: 409-14. PMID 7308192 DOI: 10.1111/J.1432-1033.1981.Tb05623.X  0.361
1982 Groen AK, Vervoorn RC, Wanders RJA, Van der Meer R, Tager JM. An evaluation of the metabolite indicator method for determining the cytosolic phosphate potential in rat liver cells Bba - Molecular Cell Research. 721: 172-177. PMID 7138915 DOI: 10.1016/0167-4889(82)90065-9  0.355
1982 Groen AK, Sips HJ, Vervoorn RC, Tager JM. Intracellular compartmentation and control of alanine metabolism in rat liver parenchymal cells. European Journal of Biochemistry. 122: 87-93. PMID 7060572 DOI: 10.1111/J.1432-1033.1982.Tb05851.X  0.322
1982 Ginns EI, Brady RO, Pirruccello S, Moore C, Sorrell S, Furbish FS, Murray GJ, Tager J, Barranger JA. Mutations of glucocerebrosidase: discrimination of neurologic and non-neurologic phenotypes of Gaucher disease. Proceedings of the National Academy of Sciences of the United States of America. 79: 5607-10. PMID 6957882 DOI: 10.1073/Pnas.79.18.5607  0.562
1982 Steckel F, Gieselmann V, Waheed A, Hasilik A, von Figura K, Elferink RO, Kalsbeek R, Tager JM. Biosynthesis of acid α-glucosidase in late-onset forms of glycogenosis type II (Pompe's disease) Febs Letters. 150: 69-76. PMID 6761145 DOI: 10.1016/0014-5793(82)81306-9  0.339
1982 Hilkens J, Tager JM, Buijs F, Brouwer-Kelder B, Van Thienen GM, Tegelaers FP, Hilgers J. Monoclonal antibodies against human acid alpha-glucosidase. Biochimica Et Biophysica Acta. 678: 7-11. PMID 6171307 DOI: 10.1016/0304-4165(81)90041-6  0.344
1981 Sips HJ, Groen AK, Tager JM. Plasma-membrane transport of alanine is rate-limiting for its metabolism in rat-liver parenchymal cells. Febs Letters. 119: 271-4. PMID 7428940 DOI: 10.1016/0014-5793(80)80269-9  0.321
1981 Hollemans M, Elferink RO, De Groot PG, Strijland A, Tager JM. Accumulation of weak bases in relation to intralysosomal pH in cultured human skin fibroblasts. Biochimica Et Biophysica Acta. 643: 140-51. PMID 7236683 DOI: 10.1016/0005-2736(81)90226-1  0.525
1981 De Groot PG, Ovde Elferink RO, Hollemans M, Strijland A, Westerveld A, Meera Khan P, Tager JM. Inactivation by chloroquine of alpha-galactosidase in cultured human skin fibroblasts. Experimental Cell Research. 136: 327-33. PMID 6273196 DOI: 10.1016/0014-4827(81)90011-2  0.65
1981 Schram A, Tager JM. The specificity of lysosomal hydrolases: human α-galactosidase isoenzymes Trends in Biochemical Sciences. 6: 328-330. DOI: 10.1016/0968-0004(81)90117-1  0.362
1980 Wanders RJ, Hoek JB, Tager JM. Origin of the ammonia found in protein-free extracts of rat-liver mitochondria and rat hepatocytes. European Journal of Biochemistry. 110: 197-202. PMID 7439158 DOI: 10.1111/J.1432-1033.1980.Tb04855.X  0.568
1980 de Groot PG, Strijland A, Kalsbeek R, Meera Khan P, Westerveld A, Hamers MN, Tager JM. Effect of 2-deoxyglucose on lysosomal enzymes in cultured human skin fibroblasts. Experimental Cell Research. 126: 207-16. PMID 6244168 DOI: 10.1016/0014-4827(80)90487-5  0.655
1979 Schram AW, Hamers MN, Samson MR, Cordus S, De Jonge A, Brown I, Robinson D, Tager JM. Factors affecting the hydrolysis of ceramide-3 by alpha-galactosidase A from human liver. Biochimica Et Biophysica Acta. 568: 59-70. PMID 36166 DOI: 10.1016/0005-2744(79)90273-0  0.318
1979 Schram AW, Brouwer-Kelder B, Donker-Koopman WE, Loonen C, Hamers MN, Tager JM. Use of immobilized antibodies in investigating acid alpha-glucosidase in urine in relation to Pompe's disease. Biochimica Et Biophysica Acta. 567: 370-83. PMID 36157 DOI: 10.1016/0005-2744(79)90123-2  0.35
1979 Schram AW, Hamers MN, Oldenbroek-Haverkamp E, Strijland A, de Jonge A, van den Bergh FA, Tager JM. Properties of immobilized fig alpha-galactosidase and effect on ceramide-3 content of plasma from patients with Fabry's disease. Biochimica Et Biophysica Acta. 527: 456-64. PMID 31916 DOI: 10.1016/0005-2744(78)90359-5  0.379
1978 Hensgens HE, Meijer AJ, Williamson JR, Gimpel JA, Tager JM. Prolone metabolism in isolated rat liver cells. The Biochemical Journal. 170: 699-707. PMID 646809 DOI: 10.1042/Bj1700699  0.312
1978 Akerboom TP, Bookelman H, Zuurendonk PF, van der Meer R, Tager JM. Intramitochondrial and extramitochondrial concentrations of adenine nucleotides and inorganic phosphate in isolated hepatocytes from fasted rats. European Journal of Biochemistry. 84: 413-20. PMID 639797 DOI: 10.1111/J.1432-1033.1978.Tb12182.X  0.331
1978 de Groot PG, Westerveld A, Meera Khan P, Tager JM. Localization of a gene for human alpha-galactosidase B (= n-acetyl-alpha-d-galactosaminidase) on chromosome 22. Human Genetics. 44: 305-12. PMID 215508 DOI: 10.1007/Bf00394295  0.604
1978 Schram AW, De Groot PG, Hamers MN, Brouwer-Kelder B, Donker-Koopman WE, Tager JM. Further characterization of two forms of N-acetyl-alpha-galactosaminidase from human liver. Biochimica Et Biophysica Acta. 525: 410-6. PMID 210819 DOI: 10.1016/0005-2744(78)90236-X  0.509
1978 Ejiofor A, Robinson D, Wise D, Hamers MN, Tager JM. Hair root analysis in heterozygotes for Fabry's disease. Advances in Experimental Medicine and Biology. 101: 719-25. PMID 208370 DOI: 10.1007/978-1-4615-9071-2_66  0.347
1978 Schram AW, Ho MW, Cordus S, Samson M, Hamers MN, Brown J, Robinson D, Tager JM. Effect of detergents on ceramide-3 hydrolysis by alpha-galactosidase A. Advances in Experimental Medicine and Biology. 101: 531-5. PMID 208366 DOI: 10.1007/978-1-4615-9071-2_48  0.348
1978 de Groot PG, Hamers MN, Westerveld A, Schram AW, Meera Khan P, Tager JM. A new immunochemical method for the quantitative measurement of specific gene products in man-rodent somatic cell hybrids. Human Genetics. 44: 295-304. PMID 83282 DOI: 10.1007/Bf00394294  0.635
1977 Hamers MN, Westerveld A, Khan M, Tager JM. Characterization of α-galactosidase isoenzymes in normal and fabry human-Chinese hamster somatic cell hybrids Human Genetics. 36: 289-297. PMID 404232 DOI: 10.1007/Bf00446279  0.557
1976 Reijngoud DJ, Oud PS, Kás J, Tager JM. Relationship between medium pH and that of the lysosomal matrix as studied by two independent methods. Biochimica Et Biophysica Acta. 448: 290-302. PMID 9156 DOI: 10.1016/0005-2736(76)90243-1  0.301
1974 Rietra PJ, Molenaar JL, Hamers MN, Tager JM, Borst P. Investigation of the alpha-galactosidase deficiency in Fabry's disease using antibodies against the purified enzyme. European Journal of Biochemistry. 46: 89-98. PMID 4212108 DOI: 10.1111/J.1432-1033.1974.Tb03600.X  0.366
1974 Hoek JB, Ernster L, de Haan EJ, Tager JM. The nicotinamide nucleotide specificity of glutamate dehydrogenase in intact rat-liver mitochondria. Biochimica Et Biophysica Acta. 333: 546-59. PMID 4152605 DOI: 10.1016/0005-2728(74)90138-8  0.49
1973 Hoek JB, Tager JM. The oxidoreduction state of free NAD(P) and mass-action ratio of total nicotinamide nucleotides in isolated ratliver mitochondria Bba - Bioenergetics. 325: 197-212. PMID 4148618 DOI: 10.1016/0005-2728(73)90096-0  0.494
1972 Meijer AJ, Brouwer A, Reijngoud DJ, Hoek JB, Tager JM. Transport of glutamate in rat-liver mitochondria. Biochimica Et Biophysica Acta. 283: 421-9. PMID 4649357 DOI: 10.1016/0005-2728(72)90259-9  0.467
1971 Sluse FE, Meijer AJ, Tager JM. Anion translocators in rat-heart mitochondria. Febs Letters. 18: 149-153. PMID 11946108 DOI: 10.1016/0014-5793(71)80432-5  0.306
1971 Lofrumento NE, Hoek JB, Meyer AJ, Tager JM. Phosphate transport in rat-liver mitochondria. Biochimica Et Biophysica Acta. 226: 297-308. PMID 5575160 DOI: 10.1016/0005-2728(71)90096-X  0.48
1969 Hoek JB, Charles R, De Haan EJ, Tager JM. Glutamate oxidation in rat-liver homogenate. Biochimica Et Biophysica Acta. 172: 407-16. PMID 5782247 DOI: 10.1016/0005-2728(69)90137-6  0.465
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