Neil R. Cashman - Publications

Affiliations: 
McGill University, Montreal, QC, Canada 
Area:
Neuroscience Biology, Medicine and Surgery

146 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Pokrishevsky E, Grad LI, Cashman NR. TDP-43 or FUS-induced misfolded human wild-type SOD1 can propagate intercellularly in a prion-like fashion. Scientific Reports. 6: 22155. PMID 26926802 DOI: 10.1038/srep22155  0.72
2016 Silverman JM, Fernando SM, Grad LI, Hill AF, Turner BJ, Yerbury JJ, Cashman NR. Disease Mechanisms in ALS: Misfolded SOD1 Transferred Through Exosome-Dependent and Exosome-Independent Pathways. Cellular and Molecular Neurobiology. PMID 26908139 DOI: 10.1007/s10571-015-0294-3  0.72
2016 Yerbury JJ, Ooi L, Dillin A, Saunders DN, Hatters DM, Beart PM, Cashman NR, Wilson MR, Ecroyd H. Walking the tightrope: Proteostasis and neurodegenerative disease. Journal of Neurochemistry. PMID 26872075 DOI: 10.1111/jnc.13575  0.72
2016 Coulthart MB, Jansen GH, Cashman NR. Evidence for transmissibility of Alzheimer disease pathology: Cause for concern? Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. PMID 26833733 DOI: 10.1503/cmaj.151257  0.72
2015 Zeineddine R, Pundavela JF, Corcoran L, Stewart EM, Do-Ha D, Bax M, Guillemin G, Vine KL, Hatters DM, Ecroyd H, Dobson CM, Turner BJ, Ooi L, Wilson MR, Cashman NR, et al. SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation. Molecular Neurodegeneration. 10: 57. PMID 26520394 DOI: 10.1186/s13024-015-0053-4  0.72
2015 Mackenzie IR, Frick P, Grässer FA, Gendron TF, Petrucelli L, Cashman NR, Edbauer D, Kremmer E, Prudlo J, Troost D, Neumann M. Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers. Acta Neuropathologica. PMID 26374446 DOI: 10.1007/s00401-015-1476-2  0.72
2015 Johnson CJ, Carlson CM, Morawski AR, Manthei A, Cashman NR. Assessing transmissible spongiform encephalopathy species barriers with an in vitro prion protein conversion assay. Journal of Visualized Experiments : Jove. PMID 25867521 DOI: 10.3791/52522  0.72
2015 Grad LI, Fernando SM, Cashman NR. From molecule to molecule and cell to cell: prion-like mechanisms in amyotrophic lateral sclerosis. Neurobiology of Disease. 77: 257-65. PMID 25701498 DOI: 10.1016/j.nbd.2015.02.009  0.72
2014 Grad LI, Pokrishevsky E, Silverman JM, Cashman NR. Exosome-dependent and independent mechanisms are involved in prion-like transmission of propagated Cu/Zn superoxide dismutase misfolding. Prion. 8: 331-5. PMID 25551548 DOI: 10.4161/19336896.2014.983398  0.72
2014 Wang MD, Gomes J, Cashman NR, Little J, Krewski D. A meta-analysis of observational studies of the association between chronic occupational exposure to lead and amyotrophic lateral sclerosis. Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine. 56: 1235-42. PMID 25479292 DOI: 10.1097/JOM.0000000000000323  0.72
2014 Wang MD, Gomes J, Cashman NR, Little J, Krewski D. Intermediate CAG repeat expansion in the ATXN2 gene is a unique genetic risk factor for ALS--a systematic review and meta-analysis of observational studies. Plos One. 9: e105534. PMID 25148523 DOI: 10.1371/journal.pone.0105534  0.72
2014 Tyshenko MG, Bertram L, Li L, ElSaadany S, Samis J, Krewski D, Cashman NR. Update on the provisional estimation of developing iatrogenic variant Creutzfeldt-Jakob disease from human islet cell transplantation procedures. Transplantation. 97: e73-5. PMID 24933255 DOI: 10.1097/TP.0000000000000176  0.72
2014 Grad LI, Yerbury JJ, Turner BJ, Guest WC, Pokrishevsky E, O'Neill MA, Yanai A, Silverman JM, Zeineddine R, Corcoran L, Kumita JR, Luheshi LM, Yousefi M, Coleman BM, Hill AF, ... ... Cashman NR, et al. Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 111: 3620-5. PMID 24550511 DOI: 10.1073/pnas.1312245111  0.72
2014 Taschuk R, Marciniuk K, Määttänen P, Madampage C, Hedlin P, Potter A, Lee J, Cashman NR, Griebel PJ, Napper S. Safety, specificity and immunogenicity of a PrP(Sc)-specific prion vaccine based on the YYR disease specific epitope. Prion. 8: 51-9. PMID 24509522 DOI: 10.4161/pri.27962  0.72
2014 Marciniuk K, Määttänen P, Taschuk R, Airey TD, Potter A, Cashman NR, Griebel P, Napper S. Development of a multivalent, PrP(Sc)-specific prion vaccine through rational optimization of three disease-specific epitopes. Vaccine. 32: 1988-97. PMID 24486363 DOI: 10.1016/j.vaccine.2014.01.027  0.72
2014 Coulthart MB, Jansen GH, Cashman NR. Interpretation of cerebrospinal fluid protein tests in the diagnosis of sporadic Creutzfeldt-Jakob disease: an evidence-based approach. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 186: E333-9. PMID 24446456 DOI: 10.1503/cmaj.130720  0.72
2014 Grad LI, Cashman NR. Prion-like activity of Cu/Zn superoxide dismutase: implications for amyotrophic lateral sclerosis. Prion. 8: 33-41. PMID 24394345 DOI: 10.4161/pri.27602  0.72
2013 Madampage CA, Marciniuk K, Määttänen P, Cashman NR, Potter A, Lee JS, Napper S. Nanopore analysis reveals differences in structural stability of ovine PrP(C) proteins corresponding to scrapie susceptible (VRQ) and resistance (ARR) genotypes. Prion. 7: 511-9. PMID 24401607 DOI: 10.4161/pri.27502  0.72
2013 Mercer RC, Ma L, Watts JC, Strome R, Wohlgemuth S, Yang J, Cashman NR, Coulthart MB, Schmitt-Ulms G, Jhamandas JH, Westaway D. The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6. The Journal of Biological Chemistry. 288: 37241-55. PMID 24225951 DOI: 10.1074/jbc.M113.488650  0.72
2013 Ostapchenko VG, Beraldo FH, Mohammad AH, Xie YF, Hirata PH, Magalhaes AC, Lamour G, Li H, Maciejewski A, Belrose JC, Teixeira BL, Fahnestock M, Ferreira ST, Cashman NR, Hajj GN, et al. The prion protein ligand, stress-inducible phosphoprotein 1, regulates amyloid-β oligomer toxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16552-64. PMID 24133259 DOI: 10.1523/JNEUROSCI.3214-13.2013  0.72
2013 Määttänen P, Taschuk R, Ross L, Marciniuk K, Bertram L, Potter A, Cashman NR, Napper S. PrP(Sc)-specific antibodies do not induce prion disease or misfolding of PrP(C) in highly susceptible Tga20 mice. Prion. 7: 434-9. PMID 24105298 DOI: 10.4161/pri.26639  0.72
2013 Madampage CA, Määttänen P, Marciniuk K, Brownlie R, Andrievskaia O, Potter A, Cashman NR, Lee JS, Napper S. Binding of bovine T194A PrP(C) by PrP(Sc)-specific antibodies: potential implications for immunotherapy of familial prion diseases. Prion. 7: 301-11. PMID 23787697 DOI: 10.4161/pri.25148  0.72
2013 Jetha NN, Semenchenko V, Wishart DS, Cashman NR, Marziali A. Nanopore analysis of wild-type and mutant prion protein (PrP(C)): single molecule discrimination and PrP(C) kinetics. Plos One. 8: e54982. PMID 23393562 DOI: 10.1371/journal.pone.0054982  0.72
2013 Airey TD, Cashman NR. The tyr-tyr-arg prion-specific epitope: Update and context Prions and Diseases. 2: 233-255. DOI: 10.1007/978-1-4614-5338-3_15  0.72
2012 Cashman NR, Chernoff YO. A special focus issue on the materials of Prion 2011 meeting in Montreal, Canada. Prion. 6: 95-6. PMID 22634715 DOI: 10.4161/pri.20455  0.72
2012 Pokrishevsky E, Grad LI, Yousefi M, Wang J, Mackenzie IR, Cashman NR. Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis. Plos One. 7: e35050. PMID 22493728 DOI: 10.1371/journal.pone.0035050  0.72
2011 Guest WC, Silverman JM, Pokrishevsky E, O'Neill MA, Grad LI, Cashman NR. Generalization of the prion hypothesis to other neurodegenerative diseases: an imperfect fit. Journal of Toxicology and Environmental Health. Part A. 74: 1433-59. PMID 22043906 DOI: 10.1080/15287394.2011.618967  0.72
2011 Coulthart MB, Jansen GH, Olsen E, Godal DL, Connolly T, Choi BC, Wang Z, Cashman NR. Diagnostic accuracy of cerebrospinal fluid protein markers for sporadic Creutzfeldt-Jakob disease in Canada: a 6-year prospective study. Bmc Neurology. 11: 133. PMID 22032272 DOI: 10.1186/1471-2377-11-133  0.72
2011 Grad LI, Guest WC, Yanai A, Pokrishevsky E, O'Neill MA, Gibbs E, Semenchenko V, Yousefi M, Wishart DS, Plotkin SS, Cashman NR. Intermolecular transmission of superoxide dismutase 1 misfolding in living cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 16398-403. PMID 21930926 DOI: 10.1073/pnas.1102645108  0.72
2011 Taghibiglou C, Lu J, Mackenzie IR, Wang YT, Cashman NR. Sterol regulatory element binding protein-1 (SREBP1) activation in motor neurons in excitotoxicity and amyotrophic lateral sclerosis (ALS): Indip, a potential therapeutic peptide. Biochemical and Biophysical Research Communications. 413: 159-63. PMID 21871872 DOI: 10.1016/j.bbrc.2011.08.011  0.72
2011 Perez-Pineiro R, Bjorndahl TC, Berjanskii MV, Hau D, Li L, Huang A, Lee R, Gibbs E, Ladner C, Dong YW, Abera A, Cashman NR, Wishart DS. The prion protein binds thiamine. The Febs Journal. 278: 4002-14. PMID 21848803 DOI: 10.1111/j.1742-4658.2011.08304.x  0.72
2011 Julien O, Chatterjee S, Bjorndahl TC, Sweeting B, Acharya S, Semenchenko V, Chakrabartty A, Pai EF, Wishart DS, Sykes BD, Cashman NR. Relative and regional stabilities of the hamster, mouse, rabbit, and bovine prion proteins toward urea unfolding assessed by nuclear magnetic resonance and circular dichroism spectroscopies. Biochemistry. 50: 7536-45. PMID 21800884 DOI: 10.1021/bi200731e  0.72
2011 Vanderperre B, Staskevicius AB, Tremblay G, McCoy M, O'Neill MA, Cashman NR, Roucou X. An overlapping reading frame in the PRNP gene encodes a novel polypeptide distinct from the prion protein. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2373-86. PMID 21478263 DOI: 10.1096/fj.10-173815  0.72
2011 Van Dorsselaer A, Carapito C, Delalande F, Schaeffer-Reiss C, Thierse D, Diemer H, McNair DS, Krewski D, Cashman NR. Detection of prion protein in urine-derived injectable fertility products by a targeted proteomic approach. Plos One. 6: e17815. PMID 21448279 DOI: 10.1371/journal.pone.0017815  0.72
2011 Guest WC, Cashman NR, Plotkin SS. A theory for the anisotropic and inhomogeneous dielectric properties of proteins Physical Chemistry Chemical Physics. 13: 6286-6295. PMID 21359369 DOI: 10.1039/c0cp02061c  0.72
2011 Ryu H, Jeon GS, Cashman NR, Kowall NW, Lee J. Differential expression of c-Ret in motor neurons versus non-neuronal cells is linked to the pathogenesis of ALS. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 342-52. PMID 21283077 DOI: 10.1038/labinvest.2010.203  0.72
2011 Hinnell C, Coulthart MB, Jansen GH, Cashman NR, Lauzon J, Clark A, Costello F, White C, Midha R, Wiebe S, Furtado S. Gerstmann-Straussler-Scheinker disease due to a novel prion protein gene mutation. Neurology. 76: 485-7. PMID 21282596 DOI: 10.1212/WNL.0b013e31820a0ab2  0.72
2011 Guest WC, Plotkin SS, Cashman NR. Toward a mechanism of prion misfolding and structural models of PrP Sc: Current knowledge and future directions Journal of Toxicology and Environmental Health - Part a: Current Issues. 74: 154-160. PMID 21218344 DOI: 10.1080/15287394.2011.529065  0.72
2011 Cashman NR, Darshan S, Krewski D, Tyshenko MG. Preface. Prion research in perspective. Journal of Toxicology and Environmental Health. Part A. 74: 71-2. PMID 21218335 DOI: 10.1080/15287394.2011.544239  0.72
2010 Khan MQ, Sweeting B, Mulligan VK, Arslan PE, Cashman NR, Pai EF, Chakrabartty A. Prion disease susceptibility is affected by beta-structure folding propensity and local side-chain interactions in PrP. Proceedings of the National Academy of Sciences of the United States of America. 107: 19808-13. PMID 21041683 DOI: 10.1073/pnas.1005267107  0.72
2010 Li L, Napper S, Cashman NR. Immunotherapy for prion diseases: opportunities and obstacles. Immunotherapy. 2: 269-82. PMID 20635933 DOI: 10.2217/imt.10.3  0.72
2010 Guest WC, Cashman NR, Plotkin SS. Electrostatics in the stability and misfolding of the prion protein: Salt bridges, self energy, and solvation Biochemistry and Cell Biology. 88: 371-381. PMID 20453937 DOI: 10.1139/O09-180  0.72
2010 Hedlin PD, Cashman NR, Li L, Gupta J, Babiuk LA, Potter AA, Griebel P, Napper S. Design and delivery of a cryptic PrP(C) epitope for induction of PrP(Sc)-specific antibody responses. Vaccine. 28: 981-8. PMID 19925901 DOI: 10.1016/j.vaccine.2009.10.134  0.72
2009 Haddon DJ, Hughes MR, Antignano F, Westaway D, Cashman NR, McNagny KM. Prion protein expression and release by mast cells after activation. The Journal of Infectious Diseases. 200: 827-31. PMID 19642931 DOI: 10.1086/605022  0.72
2009 Li L, Guest W, Huang A, Plotkin SS, Cashman NR. Immunological mimicry of PrPC-PrPSc interactions: antibody-induced PrP misfolding. Protein Engineering, Design & Selection : Peds. 22: 523-9. PMID 19602568 DOI: 10.1093/protein/gzp038  0.72
2008 Rutherford NJ, Zhang YJ, Baker M, Gass JM, Finch NA, Xu YF, Stewart H, Kelley BJ, Kuntz K, Crook RJ, Sreedharan J, Vance C, Sorenson E, Lippa C, Bigio EH, ... ... Cashman NR, et al. Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis. Plos Genetics. 4: e1000193. PMID 18802454 DOI: 10.1371/journal.pgen.1000193  0.72
2008 Vande Velde C, Miller TM, Cashman NR, Cleveland DW. Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 105: 4022-7. PMID 18296640 DOI: 10.1073/pnas.0712209105  0.72
2008 Yuan J, Dong Z, Guo JP, McGeehan J, Xiao X, Wang J, Cali I, McGeer PL, Cashman NR, Bessen R, Surewicz WK, Kneale G, Petersen RB, Gambetti P, Zou WQ. Accessibility of a critical prion protein region involved in strain recognition and its implications for the early detection of prions. Cellular and Molecular Life Sciences : Cmls. 65: 631-43. PMID 18193391 DOI: 10.1007/s00018-007-7478-z  0.72
2007 Li L, Coulthart MB, Balachandran A, Chakrabartty A, Cashman NR. Species barriers for chronic wasting disease by in vitro conversion of prion protein. Biochemical and Biophysical Research Communications. 364: 796-800. PMID 17964288 DOI: 10.1016/j.bbrc.2007.10.087  0.72
2007 Rakhit R, Robertson J, Vande Velde C, Horne P, Ruth DM, Griffin J, Cleveland DW, Cashman NR, Chakrabartty A. An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS. Nature Medicine. 13: 754-9. PMID 17486090 DOI: 10.1038/nm1559  0.72
2007 Griffin JK, Terry LA, Jackman R, Yousefi M, Cashman NR. Decreased cell surface prion protein in mouse models of prion disease. Neuroreport. 18: 1-6. PMID 17259851 DOI: 10.1097/01.wnr.0000239967.06438.21  0.72
2006 Kalra S, Vitale A, Cashman NR, Genge A, Arnold DL. Cerebral degeneration predicts survival in amyotrophic lateral sclerosis Journal of Neurology, Neurosurgery and Psychiatry. 77: 1253-1255. PMID 16835288 DOI: 10.1136/jnnp.2006.090696  0.72
2006 Lehto MT, Peery HE, Cashman NR. Current and future molecular diagnostics for prion diseases. Expert Review of Molecular Diagnostics. 6: 597-611. PMID 16824033 DOI: 10.1586/14737159.6.4.597  0.72
2005 Griffin JK, Cashman NR. Progress in prion vaccines and immunotherapies. Expert Opinion On Biological Therapy. 5: 97-110. PMID 15709913 DOI: 10.1517/14712598.5.1.97  0.72
2005 Trojan DA, Cashman NR. Post-poliomyelitis syndrome. Muscle & Nerve. 31: 6-19. PMID 15599928 DOI: 10.1002/mus.20259  0.72
2004 Fukada K, Zhang F, Vien A, Cashman NR, Zhu H. Mitochondrial proteomic analysis of a cell line model of familial amyotrophic lateral sclerosis. Molecular & Cellular Proteomics : McP. 3: 1211-23. PMID 15501831 DOI: 10.1074/mcp.M400094-MCP200  0.72
2004 Cashman NR, Caughey B. Prion diseases--close to effective therapy? Nature Reviews. Drug Discovery. 3: 874-84. PMID 15459678 DOI: 10.1038/nrd1525  0.72
2004 Rakhit R, Crow JP, Lepock JR, Kondejewski LH, Cashman NR, Chakrabartty A. Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis. The Journal of Biological Chemistry. 279: 15499-504. PMID 14734542 DOI: 10.1074/jbc.M313295200  0.72
2004 Gorochov G, Deslys JP, Paramithiotis E, Pinard M, Lawton T, LaBoissiere S, Leathers VL, Zou WQ, Estey LA, Lamontagne J, Lehto MT, Kondejewski LH, Francoeur GP, Papadopoulos M, Haghighat A, ... ... Cashman NR, et al. Properties of a disease-specific prion probe [1] (multiple letters) Nature Medicine. 10: 11-12. PMID 14702617  0.72
2004 Cashman NR, Trojan DA. Electrophysiology of Postpolio Syndrome Postpolio Syndrome. 57-60. DOI: 10.1016/B978-1-56053-606-2.50008-1  0.72
2004 Trojan DA, Finch L, Costa DD, Cashman NR. Evaluating and Treating Symptomatic Postpolio Patients Postpolio Syndrome. 21-35. DOI: 10.1016/B978-1-56053-606-2.50006-8  0.72
2003 Qin Y, Duquette P, Zhang Y, Olek M, Da RR, Richardson J, Antel JP, Talbot P, Cashman NR, Tourtellotte WW, Wekerle H, Van Den Noort S. Intrathecal B-cell clonal expansion, an early sign of humoral immunity, in the cerebrospinal fluid of patients with clinically isolated syndrome suggestive of multiple sclerosis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 83: 1081-8. PMID 12861047 DOI: 10.1097/01.LAB.0000077008.24259.0D  0.72
2003 Paramithiotis E, Pinard M, Lawton T, LaBoissiere S, Leathers VL, Zou WQ, Estey LA, Lamontagne J, Lehto MT, Kondejewski LH, Francoeur GP, Papadopoulos M, Haghighat A, Spatz SJ, Head M, ... ... Cashman NR, et al. A prion protein epitope selective for the pathologically misfolded conformation. Nature Medicine. 9: 893-9. PMID 12778138 DOI: 10.1038/nm883  0.72
2003 Bishop A, Cashman NR. Induced adaptive resistance to oxidative stress in the CNS: a discussion on possible mechanisms and their therapeutic potential. Current Drug Metabolism. 4: 171-84. PMID 12678694 DOI: 10.2174/1389200033489514  0.72
2003 Kalra S, Cashman NR, Caramanos Z, Genge A, Arnold DL. Gabapentin therapy for amyotrophic lateral sclerosis: lack of improvement in neuronal integrity shown by MR spectroscopy. Ajnr. American Journal of Neuroradiology. 24: 476-80. PMID 12637300  0.72
2002 Armstrong P, Cashman NR, Cook DJ, Feeny DH, Ghali WA, de Gruijl FR, Hall JG, Herbert CP, Iscoe N, Jadad AR, Kassirer JP, McAlister FA, McGeer AJ, MacMillan HL, Moher D, et al. A letter from CMAJ's editorial board to the CMA. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 167: 1230; author reply 1. PMID 12451066  0.72
2002 Rakhit R, Cunningham P, Furtos-Matei A, Dahan S, Qi XF, Crow JP, Cashman NR, Kondejewski LH, Chakrabartty A. Oxidation-induced misfolding and aggregation of superoxide dismutase and its implications for amyotrophic lateral sclerosis. The Journal of Biological Chemistry. 277: 47551-6. PMID 12356748 DOI: 10.1074/jbc.M207356200  0.72
2002 Zou WQ, Cashman NR. Acidic pH and detergents enhance in vitro conversion of human brain PrPC to a PrPSc-like form. The Journal of Biological Chemistry. 277: 43942-7. PMID 12161431 DOI: 10.1074/jbc.M203611200  0.72
2001 Mandler RN, Anderson FA, Miller RG, Clawson L, Cudkowicz M, Del Bene M, Bradley WG, Boynton de Sepulveda LI, Brooks BR, Cashman NR, Graves M, Harati Y, Heiman-Patterson T, Lyon M, Mitsumoto H, et al. The ALS patient care database: Insights into end-of-life care in ALS Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. 2: 203-208. PMID 11958732 DOI: 10.1080/14660820152882214  0.72
2001 Cashman NR. Transmissible spongiform encephalopathies: vaccine issues. Developments in Biologicals. 106: 455-9; discussion 46. PMID 11761262  0.72
2001 Zou WQ, Yang DS, Fraser PE, Cashman NR, Chakrabartty A. All or none fibrillogenesis of a prion peptide. European Journal of Biochemistry / Febs. 268: 4885-91. PMID 11559357 DOI: 10.1046/j.1432-1327.2001.02415.x  0.72
2001 Usuki S, Ren J, Utsunomiya I, Cashman NR, Inokuchi J, Miyatake T. GM2 ganglioside regulates the function of ciliary neurotrophic factor receptor in murine immortalized motor neuron-like cells (NSC-34). Neurochemical Research. 26: 375-82. PMID 11495348 DOI: 10.1023/A:1010999014657  0.72
2001 Coulthart MB, Cashman NR. Variant Creutzfeldt-Jakob disease: a summary of current scientific knowledge in relation to public health. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 165: 51-8. PMID 11468957  0.72
2001 Morelon E, Dodelet V, Lavery P, Cashman NR, Loertscher R. The failure of Daudi cells to express the cellular prion protein is caused by a lack of glycosyl-phosphatidylinositol anchor formation. Immunology. 102: 242-7. PMID 11260330 DOI: 10.1046/j.1365-2567.2001.01166.x  0.72
2001 Trojan DA, Collet J, Pollak MN, Shapiro S, Jubelt B, Miller RG, Agre JC, Munsat TL, Hollander D, Tandan R, Robinson A, Finch L, Ducruet T, Cashman NR. Serum insulin-like growth factor-I (IGF-I) does not correlate positively with isometric strength, fatigue, and quality of life in post-polio syndrome. Journal of the Neurological Sciences. 182: 107-15. PMID 11137515 DOI: 10.1016/S0022-510X(00)00459-7  0.72
2000 Brown P, Preece M, Brandel JP, Sato T, McShane L, Zerr I, Fletcher A, Will RG, Pocchiari M, Cashman NR, d'Aignaux JH, Cervenáková L, Fradkin J, Schonberger LB, Collins SJ. Iatrogenic Creutzfeldt-Jakob disease at the millennium. Neurology. 55: 1075-81. PMID 11071481  0.72
1999 Jung SS, Cashman NR. Processing of the beta-amyloid precursor protein in ex vivo human brain cells. Neuroreport. 10: 3875-9. PMID 10716226  0.72
1999 Jung SS, Gauthier S, Cashman NR. Beta-amyloid precursor protein is detectable on monocytes and is increased in Alzheimer's disease. Neurobiology of Aging. 20: 249-57. PMID 10588572 DOI: 10.1016/S0197-4580(99)00051-2  0.72
1999 Cashman NR. Do the benefits of currently available treatments justify early diagnosis and announcement? Arguments for. Neurology. 53: S50-2; discussion S5. PMID 10560639  0.72
1999 Trojan DA, Collet JP, Shapiro S, Jubelt B, Miller RG, Agre JC, Munsat TL, Hollander D, Tandan R, Granger C, Robinson A, Finch L, Ducruet T, Cashman NR. A multicenter, randomized, double-blinded trial of pyridostigmine in postpolio syndrome. Neurology. 53: 1225-33. PMID 10522877  0.72
1999 Kalra S, Arnold DL, Cashman NR. Biological markers in the diagnosis and treatment of ALS Journal of the Neurological Sciences. 165. PMID 10448978 DOI: 10.1016/S0022-510X(99)00023-4  0.72
1999 Bishop A, Marquis JC, Cashman NR, Demple B. Adaptive resistance to nitric oxide in motor neurons Free Radical Biology and Medicine. 26: 978-986. PMID 10232842 DOI: 10.1016/S0891-5849(98)00284-6  0.72
1999 Keller JN, Hanni KB, Pedersen WA, Cashman NR, Mattson MP, Gabbita SP, Friebe V, Markesbery WR. Opposing actions of native and oxidized lipoprotein on motor neuron-like cells. Experimental Neurology. 157: 202-10. PMID 10222123 DOI: 10.1006/exnr.1999.7043  0.72
1999 Arbour N, Côté G, Lachance C, Tardieu M, Cashman NR, Talbot PJ. Acute and persistent infection of human neural cell lines by human coronavirus OC43. Journal of Virology. 73: 3338-50. PMID 10074188  0.72
1999 Arbour N, Ekandé S, Côté G, Lachance C, Chagnon F, Tardieu M, Cashman NR, Talbot PJ. Persistent infection of human oligodendrocytic and neuroglial cell lines by human coronavirus 229E. Journal of Virology. 73: 3326-37. PMID 10074187  0.72
1999 Usuki S, Cashman NR, Miyatake T. GM2 promotes ciliary neurotrophic factor-dependent rescue of immortalized motor neuron-like cell (NSC-34). Neurochemical Research. 24: 281-6. PMID 9972876 DOI: 10.1023/A:1022522306946  0.72
1999 Pedersen WA, Cashman NR, Mattson MP. The lipid peroxidation product 4-hydroxynonenal impairs glutamate and glucose transport and choline acetyltransferase activity in NSC-19 motor neuron cells. Experimental Neurology. 155: 1-10. PMID 9918699 DOI: 10.1006/exnr.1998.6890  0.72
1999 Ellerby LM, Hackam AS, Propp SS, Ellerby HM, Rabizadeh S, Cashman NR, Trifiro MA, Pinsky L, Wellington CL, Salvesen GS, Hayden MR, Bredesen DE. Kennedy's disease: caspase cleavage of the androgen receptor is a crucial event in cytotoxicity. Journal of Neurochemistry. 72: 185-95. PMID 9886069 DOI: 10.1046/j.1471-4159.1999.0720185.x  0.72
1998 Kalra S, Cashman NR, Genge A, Arnold DL. Recovery of N-acetylaspartate in corticomotor neurons of patients with ALS after riluzole therapy Neuroreport. 9: 1757-1761. PMID 9665596  0.72
1998 Lachance C, Arbour N, Cashman NR, Talbot PJ. Involvement of aminopeptidase N (CD13) in infection of human neural cells by human coronavirus 229E. Journal of Virology. 72: 6511-9. PMID 9658094  0.72
1998 Dodelet VC, Cashman NR. Prion protein expression in human leukocyte differentiation. Blood. 91: 1556-61. PMID 9473220  0.72
1997 Trojan DA, Cashman NR. Pathophysiology and diagnosis of post-polio syndrome. Neurorehabilitation. 8: 83-92. PMID 24525979 DOI: 10.3233/NRE-1997-8203  0.72
1997 Cashman NR. A prion primer. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 157: 1381-5. PMID 9371069  0.72
1997 Ellerby HM, Martin SJ, Ellerby LM, Naiem SS, Rabizadeh S, Salvesen GS, Casiano CA, Cashman NR, Green DR, Bredesen DE. Establishment of a cell-free system of neuronal apoptosis: comparison of premitochondrial, mitochondrial, and postmitochondrial phases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6165-78. PMID 9236228  0.72
1997 Ricketts MN, Cashman NR, Stratton EE, ElSaadany S. Is Creutzfeldt-Jakob disease transmitted in blood? Emerging Infectious Diseases. 3: 155-63. PMID 9204296 DOI: 10.3201/eid0302.970208  0.72
1997 Pallister C, Jung SS, Shaw I, Nalbantoglu J, Gauthier S, Cashman NR. Lymphocyte content of amyloid precursor protein is increased in Down's syndrome and aging. Neurobiology of Aging. 18: 97-103. PMID 8983037 DOI: 10.1016/S0197-4580(96)00207-2  0.72
1996 D'Souza SD, Bonetti B, Balasingam V, Cashman NR, Barker PA, Troutt AB, Raine CS, Antel JP. Multiple sclerosis: Fas signaling in oligodendrocyte cell death. The Journal of Experimental Medicine. 184: 2361-70. PMID 8976190 DOI: 10.1084/jem.184.6.2361  0.72
1996 Jung SS, Nalbantoglu J, Cashman NR. Alzheimer's beta-amyloid precursor protein is expressed on the surface of immediately ex vivo brain cells: a flow cytometric study. Journal of Neuroscience Research. 46: 336-48. PMID 8933373 DOI: 10.1002/(SICI)1097-4547(19961101)46:3<336::AID-JNR7>3.0.CO;2-L  0.72
1996 Dodelet V, Ricketts M, Cashman NR. Emerging problems in prion disease. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 155: 549-51. PMID 8804261  0.72
1996 Fujita T, Tanaka T, Yonemasu Y, Cendes F, Cashman NR, Andermann F. Electroclinical and pathological studies after parenteral administration of domoic acid in freely moving nonanesthetized rats: An animal model of excitotoxicity Journal of Epilepsy. 9: 87-93. DOI: 10.1016/0896-6974(95)00075-5  0.72
1995 Trojan DA, Cashman NR. An open trial of pyridostigmine in post-poliomyelitis syndrome. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 22: 223-7. PMID 8529175 DOI: 10.1017/S0317167100039883  0.72
1995 Cendes F, Andermann F, Carpenter S, Zatorre RJ, Cashman NR. Temporal lobe epilepsy caused by domoic acid intoxication: evidence for glutamate receptor-mediated excitotoxicity in humans. Annals of Neurology. 37: 123-6. PMID 7818246 DOI: 10.1002/ana.410370125  0.72
1995 Trojan DA, Cashman NR. Fibromyalgia is common in a postpoliomyelitis clinic. Archives of Neurology. 52: 620-4. PMID 7763212 DOI: 10.1001/archneur.1995.00540300094019  0.72
1995 McLaurin J, Trudel GC, Shaw IT, Antel JP, Cashman NR. A human glial hybrid cell line differentially expressing genes subserving oligodendrocyte and astrocyte phenotype. Journal of Neurobiology. 26: 283-93. PMID 7707048 DOI: 10.1002/neu.480260212  0.72
1995 Trojan DA, Cashman NR. Anticholinesterases in post-poliomyelitis syndrome. Annals of the New York Academy of Sciences. 753: 285-95. PMID 7611637 DOI: 10.1111/j.1749-6632.1995.tb27554.x  0.72
1995 Jubelt B, Salazar-Grueso EF, Roos RP, Cashman NR. Antibody titer to the poliovirus in blood and cerebrospinal fluid of patients with post-polio syndrome. Annals of the New York Academy of Sciences. 753: 201-7. PMID 7611629 DOI: 10.1111/j.1749-6632.1995.tb27546.x  0.72
1995 Cashman NR, Trojan DA. Correlation of electrophysiology with pathology, pathogenesis, and anticholinesterase therapy in post-polio syndrome. Annals of the New York Academy of Sciences. 753: 138-50. PMID 7611623 DOI: 10.1111/j.1749-6632.1995.tb27540.x  0.72
1995 Matsumoto A, Yoshino H, Yuki N, Hara Y, Cashman NR, Handa S, Miyatake T. Ganglioside characterization of a cell line displaying motor neuron-like phenotype: GM2 as a possible major ganglioside in motor neurons. Journal of the Neurological Sciences. 131: 111-8. PMID 7595635 DOI: 10.1016/0022-510X(95)00101-7  0.72
1995 Antel JP, Cashman NR. Immunological findings in amyotrophic lateral sclerosis Springer Seminars in Immunopathology. 17: 17-28. PMID 7482223 DOI: 10.1007/BF00194097  0.72
1995 Ledoux S, Bergeron C, Nalbantoglu J, Gauthier S, Cashman NR. Polymerase chain reaction quantification of lymphoid amyloid precursor protein mRNAs in Alzheimer's disease and Down's syndrome Neuroscience Letters. 193: 137-139. PMID 7478160 DOI: 10.1016/0304-3940(95)11681-L  0.72
1994 Talbot PJ, Ekande S, Cashman NR, Mounir S, Stewart JN. Neurotropism of human coronavirus 229E Advances in Experimental Medicine and Biology. 342: 339-346. PMID 8209751  0.72
1994 Faure MP, Gaudreau P, Shaw I, Cashman NR, Beaudet A. Synthesis of a biologically active fluorescent probe for labeling neurotensin receptors Journal of Histochemistry and Cytochemistry. 42: 755-763. PMID 8189037  0.72
1994 Trojan DA, Cashman NR, Shapiro S, Tansey CM, Esdaile JM. Predictive factors for post-poliomyelitis syndrome Archives of Physical Medicine and Rehabilitation. 75: 770-777. PMID 8024423  0.72
1994 Pioro EP, Antel JP, Cashman NR, Arnold DL. Detection of cortical neuron loss in motor neuron disease by proton magnetic resonance spectroscopic imaging in vivo Neurology. 44: 1933-1938. PMID 7936250  0.72
1994 Hasham MI, Naumann D, Kim SU, Cashman NR, Quamme GA, Krieger C. Intracellular calcium concentrations during metabolic inhibition in the motoneuron cell line NSC-19 Canadian Journal of Physiology and Pharmacology. 72: 728-737. PMID 7828081  0.72
1994 Ledoux S, Nalbantoglu J, Cashman NR. Amyloid precursor protein gene expression in neural cell lines: influence of DNA cytosine methylation Molecular Brain Research. 24: 140-144. PMID 7526112 DOI: 10.1016/0169-328X(94)90125-2  0.72
1993 Ledoux S, Rebai N, Dagenais A, Shaw IT, Nalbantoglu J, Sekaly RP, Cashman NR. Amyloid Precursor Protein in Peripheral Mononuclear Cells Is Up-Regulated with Cell Activation Journal of Immunology. 150: 5566-5575. PMID 8515076  0.72
1993 Trojan DA, Gendron D, Cashman NR. Anticholinesterase-responsive neuromuscular junction transmission defects in post-poliomyelitis fatigue Journal of the Neurological Sciences. 114: 170-177. PMID 8383188 DOI: 10.1016/0022-510X(93)90294-9  0.72
1993 Trojan DA, Gendron D, Cashman NR. Stimulation frequency-dependent neuromuscular junction transmission defects in patients with prior poliomyelitis Journal of the Neurological Sciences. 118: 150-157. PMID 8229063 DOI: 10.1016/0022-510X(93)90104-7  0.72
1993 Durham HD, Dahrouge S, Cashman NR. Evaluation of the spinal cord neuron X neuroblastoma hybrid cell line NSC- 34 as a model for neurotoxicity testing Neurotoxicology. 14: 387-396. PMID 7909362  0.72
1992 Cashman NR, Durham HD, Blusztajn JK, Oda K, Tabira T, Shaw IT, Dahrouge S, Antel JP. Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 194: 209-21. PMID 1467557 DOI: 10.1002/aja.1001940306  0.72
1992 Rosenberg LT, Hamparian VV, Salazar-Grueso EF, Roos RP, Jubelt B, Cashman NR, Dawson RB, Sharief MK. Immune responses in the post-polio syndrome [1] New England Journal of Medicine. 326: 640-642. PMID 1370857  0.72
1992 Bendheim PE, Brown HR, Rudelli RD, Scala LJ, Goller NL, Wen GY, Kascsak RJ, Cashman NR, Bolton DC. Nearly ubiquitous tissue distribution of the scrapie agent precursor protein. Neurology. 42: 149-56. PMID 1346470  0.72
1992 Maselli RA, Cashman NR, Wollman RL, Salazar-Grueso EF, Roos R. Neuromuscular transmission as a function of motor unit size in patients with prior poliomyelitis. Muscle & Nerve. 15: 648-55. PMID 1324424 DOI: 10.1002/mus.880150603  0.72
1991 Antel JP, Cashman NR. Human retrovirus and multiple sclerosis Mayo Clinic Proceedings. 66: 752-755. PMID 2072763  0.72
1991 Fishman PS, Shy ME, Hart DE, Thompson PE, Cashman NR. Antibodies to the Ganglioside Gd1B in a Patient With Motor Neuron Disease and Thyroid Adenoma Archives of Neurology. 48: 1188-1190. PMID 1953407 DOI: 10.1001/archneur.1991.00530230096030  0.72
1991 Trojan DA, Gendron D, Cashman NR. Electrophysiology and electrodiagnosis of the post-polio motor unit Orthopedics. 14: 1353-1361. PMID 1784551  0.72
1990 Schwob NG, Nalbantoglu J, Hastings KE, Mikkelsen T, Cashman NR. DNA cytosine methylation in brain of patients with Alzheimer's disease. Annals of Neurology. 28: 91-4. PMID 2375641 DOI: 10.1002/ana.410280117  0.72
1990 Cashman NR, Pouliot Y. EBV Ig-like domains [8] Nature. 343: 319. PMID 2153934  0.72
1990 Freedman MS, Loertscher R, Cashman NR, Duquette P, Blain M, Antel JP. Immunoregulatory properties of T-cell lines derived from the systemic and intrathecal compartments: A phenotypic and functional study Annals of Neurology. 27: 258-265. PMID 2139312  0.72
1990 Teitelbaum J, Zatorre RJ, Carpenter S, Gendron D, Cashman NR. Neurological sequelae of domoic acid intoxication. Canada Diseases Weekly Report = Rapport Hebdomadaire Des Maladies Au Canada. 16: 9-12. PMID 2101745  0.72
1990 Teitelbaum JS, Zatorre RJ, Carpenter S, Gendron D, Evans AC, Gjedde A, Cashman NR. Neurologic sequelae of domoic acid intoxication due to the ingestion of contaminated mussels. The New England Journal of Medicine. 322: 1781-7. PMID 1971710 DOI: 10.1056/NEJM199006213222505  0.72
1990 Cashman NR, Loertscher R, Nalbantoglu J, Shaw I, Kascsak RJ, Bolton DC, Bendheim PE. Cellular isoform of the scrapie agent protein participates in lymphocyte activation Cell. 61: 185-192. PMID 1969332 DOI: 10.1016/0092-8674(90)90225-4  0.72
1990 Salazar-Grueso EF, Grimaldi LME, Roos RP, Variakojis R, Jubelt B, Cashman NR. Oligoclonal bands in the cerebrospinal fluid of post-poliomyelitis muscular atrophy (I: Reply) Annals of Neurology. 28: 197. DOI: 10.1002/ana.410280220  0.72
1989 Farmer JP, Antel JP, Freedman M, Cashman NR, Rode H, Villemure JG. Characterization of lymphoid cells isolated from human gliomas Journal of Neurosurgery. 71: 528-533. PMID 2795172  0.72
1989 Salazar-Grueso EF, Grimaldi LME, Roos RP, Variakojis R, Jubelt B, Cashman NR. Isoelectric focusing studies of serum and cerebrospinal fluid in patients with antecedent poliomyelitis Annals of Neurology. 26: 709-713. PMID 2513770 DOI: 10.1002/ana.410260604  0.72
1988 Cashman NR, Antel JP. Amyotrophic lateral sclerosis: An immunologic perspective Immunology and Allergy Clinics of North America. 8.  0.72
1987 Cashman NR, Maselli R, Wollmann RL, Roos R, Simon R, Antel JP. Post-poliomyelitis syndrome: evidence of ongoing denervation in symptomatic and asymptomatic patients. Birth Defects Original Article Series. 23: 237-9. PMID 3620621  0.72
1987 Cashman NR, Maselli R, Wollmann RL, Roos R, Simon R, Antel JP. Late denervation in patients with antecedent paralytic poliomyelitis. The New England Journal of Medicine. 317: 7-12. PMID 3587319 DOI: 10.1056/NEJM198707023170102  0.72
1987 Jubelt B, Cashman NR. Neurological manifestations of the post-polio syndrome Critical Reviews in Neurobiology. 3: 199-220. PMID 3315237  0.72
1987 Cashman NR, Covault J, Wollman RL, Sanes JR. Neural cell adhesion molecule in normal, denervated, and myopathic human muscle. Annals of Neurology. 21: 481-9. PMID 3296947 DOI: 10.1002/ana.410210512  0.72
1986 Cashman NR, Noronha A. Accessory cell competence of ovine oligodendrocytes in mitogenic activation of human peripheral T cells Journal of Immunology. 136: 4460-4463. PMID 3486900  0.72
1986 Cashman NR, Antel JP, Hancock LW, Dawson G, Horwitz AL, Johnson WG, Huttenlocher PR, Wollmann RL. N-acetyl-beta-hexosaminidase beta locus defect and juvenile motor neuron disease: a case study. Annals of Neurology. 19: 568-72. PMID 3014997 DOI: 10.1002/ana.410190608  0.72
1986 Huttenlocher PR, Picchietti DL, Roos RP, Cashman NR, Horowitz B, Horowitz MS. Intrathecal interferon in subacute sclerosing panencephalitis. Annals of Neurology. 19: 303-5. PMID 2421637 DOI: 10.1002/ana.410190317  0.72
1985 Hancock LW, Horwitz AL, Cashman NR, Antel JP, Dawson G. N-Acetyl-β-hexosaminidase B deficiency in cultured fibroblasts from a patient with progressive motor neuron disease Biochemical and Biophysical Research Communications. 130: 1185-1192. PMID 3161509 DOI: 10.1016/0006-291X(85)91740-1  0.72
1985 Cashman NR, Gurney ME, Antel JP. Immunology of amyotrophic lateral sclerosis. Springer Seminars in Immunopathology. 8: 141-52. PMID 2408348 DOI: 10.1007/BF00197252  0.72
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