James W. Gurd - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Neuroscience Biology

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Dykstra CM, Ratnam M, Gurd JW. Neuroprotection after status epilepticus by targeting protein interactions with postsynaptic density protein 95 Journal of Neuropathology and Experimental Neurology. 68: 823-831. PMID 19535989 DOI: 10.1097/Nen.0B013E3181Ac6B70  0.355
2008 Gurd JW, Rawof S, Zhen Huo J, Dykstra C, Bissoon N, Teves L, Wallace MC, Rostas JA. Ischemia and status epilepitcus result in enhanced phosphorylation of calcium and calmodulin-stimulated protein kinase II on threonine 253. Brain Research. 1218: 158-65. PMID 18514171 DOI: 10.1016/J.Brainres.2008.04.040  0.362
2007 Besshoh S, Chen S, Brown IR, Gurd JW. Developmental changes in the association of NMDA receptors with lipid rafts. Journal of Neuroscience Research. 85: 1876-83. PMID 17492792 DOI: 10.1002/Jnr.21336  0.427
2007 Zhang G, Jung BP, Ho W, Jugloff DG, Cheung HH, Gurd JW, Wallace MC, Eubanks JH. Isolation and characterization of LCHN: a novel factor induced by transient global ischemia in the adult rat hippocampus. Journal of Neurochemistry. 101: 263-73. PMID 17394467 DOI: 10.1111/J.1471-4159.2006.04374.X  0.34
2006 Migues PV, Lehmann IT, Fluechter L, Cammarota M, Gurd JW, Sim AT, Dickson PW, Rostas JA. Phosphorylation of CaMKII at Thr253 occurs in vivo and enhances binding to isolated postsynaptic densities. Journal of Neurochemistry. 98: 289-99. PMID 16805815 DOI: 10.1111/J.1471-4159.2006.03876.X  0.407
2006 Huo JZ, Dykstra CM, Gurd JW. Increase in tyrosine phosphorylation of the NMDA receptor following the induction of status epilepticus. Neuroscience Letters. 401: 266-70. PMID 16600505 DOI: 10.1016/J.Neulet.2006.03.033  0.419
2005 Vij S, Vannucci SJ, Gurd JW. Differential effects of hypoxia-ischemia on phosphorylation of the N-methyl-D-aspartate receptor in one- and three-week-old rats. Developmental Neuroscience. 27: 211-9. PMID 16046856 DOI: 10.1159/000085994  0.382
2005 Chen S, Bawa D, Besshoh S, Gurd JW, Brown IR. Association of heat shock proteins and neuronal membrane components with lipid rafts from the rat brain. Journal of Neuroscience Research. 81: 522-9. PMID 15948182 DOI: 10.1002/Jnr.20575  0.329
2005 Besshoh S, Bawa D, Teves L, Wallace MC, Gurd JW. Increased phosphorylation and redistribution of NMDA receptors between synaptic lipid rafts and post-synaptic densities following transient global ischemia in the rat brain. Journal of Neurochemistry. 93: 186-94. PMID 15773918 DOI: 10.1111/J.1471-4159.2004.03009.X  0.419
2005 Niimura M, Moussa R, Bissoon N, Ikeda-Douglas C, Milgram NW, Gurd JW. Changes in phosphorylation of the NMDA receptor in the rat hippocampus induced by status epilepticus. Journal of Neurochemistry. 92: 1377-85. PMID 15748156 DOI: 10.1111/J.1471-4159.2005.02977.X  0.422
2004 Khan AM, Cheung HH, Gillard ER, Palarca JA, Welsbie DS, Gurd JW, Stanley BG. Lateral hypothalamic signaling mechanisms underlying feeding stimulation: differential contributions of Src family tyrosine kinases to feeding triggered either by NMDA injection or by food deprivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10603-15. PMID 15564576 DOI: 10.1523/Jneurosci.3390-04.2004  0.329
2003 Cheung HH, Teves L, Wallace MC, Gurd JW. Inhibition of protein kinase C reduces ischemia-induced tyrosine phosphorylation of the N-methyl-d-aspartate receptor. Journal of Neurochemistry. 86: 1441-9. PMID 12950452 DOI: 10.1046/J.1471-4159.2003.01951.X  0.416
2002 Aarts M, Liu Y, Liu L, Besshoh S, Arundine M, Gurd JW, Wang YT, Salter MW, Tymianski M. Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions. Science (New York, N.Y.). 298: 846-50. PMID 12399596 DOI: 10.1126/Science.1072873  0.38
2002 Gurd JW, Bissoon N, Beesley PW, Nakazawa T, Yamamoto T, Vannucci SJ. Differential effects of hypoxia-ischemia on subunit expression and tyrosine phosphorylation of the NMDA receptor in 7- and 21-day-old rats. Journal of Neurochemistry. 82: 848-56. PMID 12358790 DOI: 10.1046/J.1471-4159.2002.01026.X  0.398
2002 Boonstra R, Takagi N, Bissoon N, Vij S, Gurd JW. Trapping-induced changes in expression of the N-methyl-D-aspartate receptor in the hippocampus of snowshoe hares. Neuroscience Letters. 324: 173-6. PMID 12009516 DOI: 10.1016/S0304-3940(02)00202-1  0.343
2001 Moussa RC, Ikeda-Douglas CJ, Thakur V, Milgram NW, Gurd JW. Seizure activity results in increased tyrosine phosphorylation of the N-methyl-D-aspartate receptor in the hippocampus. Brain Research. Molecular Brain Research. 95: 36-47. PMID 11687275 DOI: 10.1016/S0169-328X(01)00231-5  0.402
2001 Cheung HH, Teves L, Wallace MC, Gurd JW. Increased phosphorylation of the NR1 subunit of the NMDA receptor following cerebral ischemia Journal of Neurochemistry. 78: 1179-1182. PMID 11553692 DOI: 10.1046/J.1471-4159.2001.0780051179.X  0.425
2001 Pei L, Teves RL, Wallace MC, Gurd JW. Transient cerebral ischemia increases tyrosine phosphorylation of the synaptic RAS-GTpase activating protein, SynGAP Journal of Cerebral Blood Flow and Metabolism. 21: 955-963. PMID 11487731 DOI: 10.1097/00004647-200108000-00008  0.418
2001 Cheung HH, Gurd JW. Tyrosine phosphorylation of the N-methyl-D-aspartate receptor by exogenous and postsynaptic density-associated Src-family kinases Journal of Neurochemistry. 78: 524-534. PMID 11483655 DOI: 10.1046/J.1471-4159.2001.00433.X  0.395
2000 Cheung HH, Takagi N, Teves L, Logan R, Wallace MC, Gurd JW. Altered association of protein tyrosine kinases with postsynaptic densities after transient cerebral ischemia in the rat brain Journal of Cerebral Blood Flow and Metabolism. 20: 505-512. PMID 10724115 DOI: 10.1097/00004647-200003000-00009  0.444
2000 Takagi N, Logan R, Teves L, Wallace MC, Gurd JW. Altered interaction between PSD-95 and the NMDA receptor following transient global ischemia Journal of Neurochemistry. 74: 169-178. PMID 10617118 DOI: 10.1046/j.1471-4159.2000.0740169.x  0.309
1999 Gurd JW, Bissoon N, Nguyen TH, Lombroso PJ, Rider CC, Beesley PW, Vannucci SJ. Hypoxia-ischemia in perinatal rat brain induces the formation of a low molecular weight isoform of striatal enriched tyrosine phosphatase (STEP). Journal of Neurochemistry. 73: 1990-4. PMID 10537057  0.304
1999 Takagi N, Cheung HH, Bissoon N, Teves L, Wallace MC, Gurd JW. The effect of transient global ischemia on the interaction of Src and Fyn with the N-methyl-D-aspartate receptor and postsynaptic densities: Possible involvement of Src homology 2 domains Journal of Cerebral Blood Flow and Metabolism. 19: 880-888. PMID 10458595 DOI: 10.1097/00004647-199908000-00007  0.423
1998 Hsu JC, Zhang Y, Takagi N, Gurd JW, Wallace MC, Zhang L, Eubanks JH. Decreased expression and functionality of NMDA receptor complexes persist in the CA1, but not in the dentate gyrus after transient cerebral ischemia Journal of Cerebral Blood Flow and Metabolism. 18: 768-775. PMID 9663507 DOI: 10.1097/00004647-199807000-00008  0.371
1998 Clark RA, Gurd JW, Bissoon N, Tricaud N, Molnar E, Zamze SE, Dwek RA, McIlhinney RA, Wing DR. Identification of lectin-purified neural glycoproteins, GPs 180, 116, and 110, with NMDA and AMPA receptor subunits: conservation of glycosylation at the synapse. Journal of Neurochemistry. 70: 2594-605. PMID 9603226 DOI: 10.1046/J.1471-4159.1998.70062594.X  0.394
1997 Gurd JW. Protein tyrosine phosphorylation: Implications for synaptic function Neurochemistry International. 31: 635-649. PMID 9364450 DOI: 10.1016/S0197-0186(97)00022-3  0.45
1997 Zhang, Hsu JC, Takagi N, Gurd JW, Wallace MC, Eubanks JH. Transient global ischemia alters NMDA receptor expression in rat hippocampus: Correlation with decreased immunoreactive protein levels of the NR2A/2B subunits, and an altered NMDA receptor functionality Journal of Neurochemistry. 69: 1983-1994. PMID 9349543 DOI: 10.1046/J.1471-4159.1997.69051983.X  0.386
1997 Takagi N, Shinno K, Teves L, Bissoon N, Wallace MC, Gurd JW. Transient ischemia differentially increases tyrosine phosphorylation of NMDA receptor subunits 2A and 2B Journal of Neurochemistry. 69: 1060-1065. PMID 9282928 DOI: 10.1046/J.1471-4159.1997.69031060.X  0.431
1997 Gurd JW, Bissoon N. The N-methyl-D-aspartate receptor subunits NR2A and NR2B bind to the SH2 domains of phospholipase C-γ Journal of Neurochemistry. 69: 623-630. PMID 9231720 DOI: 10.1046/J.1471-4159.1997.69020623.X  0.441
1996 Rostas JA, Brent VA, Voss K, Errington ML, Bliss TV, Gurd JW. Enhanced tyrosine phosphorylation of the 2B subunit of the N-methyl-D-aspartate receptor in long-term potentiation. Proceedings of the National Academy of Sciences of the United States of America. 93: 10452-6. PMID 8816821 DOI: 10.1073/Pnas.93.19.10452  0.468
1996 Mendis DB, Shahin S, Gurd JW, Brown IR. SC1, a SPARC-related glycoprotein, exhibits features of an ECM component in the developing and adult brain Brain Research. 713: 53-63. PMID 8724975 DOI: 10.1016/0006-8993(95)01472-1  0.349
1995 Au KN, Gurd JW. Tyrosine phosphorylation in a model of ischemia using the rat hippocampal slice: Specific, long-term decrease in the tyrosine phosphorylation of the postsynaptic glycoprotein PSD-GP180 Journal of Neurochemistry. 65: 1834-1841. PMID 7561882 DOI: 10.1046/J.1471-4159.1995.65041834.X  0.462
1994 Mendis DB, Shahin S, Gurd JW, Brown IR. Developmental expression in the rat cerebellum of SC1, a putative brain extracellular matrix glycoprotein related to SPARC Brain Research. 633: 197-205. PMID 8137157 DOI: 10.1016/0006-8993(94)91540-7  0.323
1994 Soulliere J, Bissoon N, Khurgel M, Gurd JW. Tyrosine phosphorylation of glycoproteins in the adult and developing rat brain Journal of Neuroscience Research. 37: 506-514. PMID 7517458 DOI: 10.1002/Jnr.490370410  0.468
1994 Willmott T, Williamson TL, Mummery R, Hawkes RB, Can A, Gurd JW, Gordon-Weeks PR, Beesley PW. Expression of PAC 1, an epitope associated with two synapse-enriched glycoproteins and a neuronal cytoskeleton-associated polypeptide in developing forebrain neurons. Neuroscience. 58: 115-29. PMID 7512700 DOI: 10.1016/0306-4522(94)90159-7  0.415
1992 Johnston IG, Rush SJ, Gurd JW, Brown IR. Molecular cloning of a novel mRNA using an antibody directed against synaptic glycoproteins. Journal of Neuroscience Research. 32: 159-66. PMID 1404491 DOI: 10.1002/Jnr.490320205  0.414
1992 Woodrow S, Bissoon N, Gurd JW. Depolarization-dependent tyrosine phosphorylation in rat brain synaptosomes Journal of Neurochemistry. 59: 857-862. PMID 1379632 DOI: 10.1111/J.1471-4159.1992.Tb08323.X  0.451
1992 Gurd JW, Brown JR, Bissoon N, Cudmore S, Ni B, Soulliere J. Glycoproteins of the post-synaptic density: Biochemical and immunochemical characterization of PSD-GP 180 Biochemical Society Transactions. 20: 379-382. PMID 1327917 DOI: 10.1042/Bst0200379  0.39
1992 Ni B, Rush S, Gurd JW, Brown IR. Molecular cloning of calmodulin mRNA species which are preferentially expressed in neurons in the rat brain Molecular Brain Research. 13: 7-17. PMID 1315919 DOI: 10.1016/0169-328X(92)90039-E  0.31
1992 Gurd JW, Bissoon N, Soulliere J. Procedures for analyzing the tyrosine phosphorylation of synaptic glycoproteins Neuroprotocols. 1: 207-214. DOI: 10.1016/1058-6741(92)90030-2  0.49
1991 Cudmore SB, Gurd JW. Postnatal Age and Protein Tyrosine Phosphorylation at Synapses in the Developing Rat Brain Journal of Neurochemistry. 57: 1240-1248. PMID 1895104 DOI: 10.1111/J.1471-4159.1991.Tb08285.X  0.422
1990 Gurd JW, Bissoon N. Phosphorylation of proteins of the postsynaptic density: Effect of development on protein tyrosine kinase and phosphorylation of the postsynaptic density glycoprotein, PSD-GP180 Journal of Neuroscience Research. 25: 336-344. PMID 2325159  0.321
1990 Paladino T, Beesley PW, Nicholson S, Gurd JW. Expression of the neuron-specific glycoprotein GP50 by granule cell cultures Brain Research. 521: 131-137. PMID 2207652 DOI: 10.1016/0006-8993(90)91533-M  0.351
1990 Howes S, Bissoon N, Ito M, Beesley PW, Gurd JW. The effect of castanospermine on the synthesis of synaptic glycoproteins by rat brain slices Neurochemical Research. 15: 257-263. PMID 2195374 DOI: 10.1007/Bf00968669  0.411
1990 Johnston IG, Paladino T, Gurd JW, Brown IR. Molecular cloning of SC1: A putative brain extracellular matrix glycoprotein showing partial similarity to osteonectin/BM40/SPARC Neuron. 4: 165-176. PMID 1690015 DOI: 10.1016/0896-6273(90)90452-L  0.363
1989 Paladino T, Beesley PW, Gurd JW. Molecular Characterization of GP50: A Neuron‐Specific, Synaptic‐Enriched Glycoprotein Journal of Neurochemistry. 53: 1902-1909. PMID 2809601 DOI: 10.1111/J.1471-4159.1989.Tb09260.X  0.371
1989 Leclerc N, Beesley PW, Brown I, Collonnier M, Gurd JW, Paladino T, Hawkes R. Synaptophysin expression during synaptogenesis in the rat cerebellar cortex Journal of Comparative Neurology. 280: 197-212. PMID 2494237 DOI: 10.1002/Cne.902800204  0.404
1988 Ellis PD, Bissoon N, Gurd JW. Synaptic protein tyrosine kinase: partial characterization and identification of endogenous substrates. Journal of Neurochemistry. 51: 611-20. PMID 3392548 DOI: 10.1111/J.1471-4159.1988.Tb01082.X  0.423
1987 Beesley PW, Paladino T, Gravel C, Hawkes RA, Gurd JW. Characterization of gp 50, a major glycoprotein present in rat brain synaptic membranes, with a monoclonal antibody. Brain Research. 408: 65-78. PMID 3594231 DOI: 10.1016/0006-8993(87)90359-3  0.446
1987 Stanojev D, Gurd JW. Characterization of Fucosyl Oligosaccharides Associated with Synaptic Membrane and Synaptic Junctional Glycoproteins Journal of Neurochemistry. 48: 1604-1611. PMID 3559570 DOI: 10.1111/J.1471-4159.1987.Tb05708.X  0.418
1986 Bank B, Gurd JW, Chute DL. Decreased phosphorylation of synaptic glycoproteins following hippocampal kindling Brain Research. 399: 390-394. PMID 3828774 DOI: 10.1016/0006-8993(86)91534-9  0.415
1986 Kearney KA, Gurd JW. Phosphorylation of synaptic membrane glycoproteins: The effects of Ca2+ and calmodulin Journal of Neurochemistry. 46: 1683-1691. PMID 3009715 DOI: 10.1111/J.1471-4159.1986.Tb08485.X  0.47
1986 BEESLEY PW, PALADINO T, GRAVEL C, HAWKES R, GURD JW. Is the major synaptic membrane concanavalin A-binding glycoprotein, gp 50, located at the synapse: studies with a monoclonal antibody Biochemical Society Transactions. 14: 769-771. DOI: 10.1042/Bst0140769  0.397
1985 Shanley B, Gurd J, Kalant H. Ethanol tolerance and enhanced calcium/calmodulin-dependent phosphorylation of synaptic membrane proteins. Neuroscience Letters. 58: 55-9. PMID 4047475 DOI: 10.1016/0304-3940(85)90328-3  0.379
1985 Gurd JW. Phosphorylation of the postsynaptic density glycoprotein gp 180 by endogenous tyrosine kinase Brain Research. 333: 385-388. PMID 4039619 DOI: 10.1016/0006-8993(85)91599-9  0.4
1985 Gurd JW, Bissoon N. In Vivo Phosphorylation of the Postsynaptic Density Glycoprotein gp180 Journal of Neurochemistry. 45: 1136-1140. PMID 4031882 DOI: 10.1111/J.1471-4159.1985.Tb05533.X  0.368
1985 Gurd JW. Phosphorylation of the Postsynaptic Density Glycoprotein gp 180 by Ca2+/Calmodulin‐Dependent Protein Kinase Journal of Neurochemistry. 45: 1128-1135. PMID 2993521 DOI: 10.1111/J.1471-4159.1985.Tb05532.X  0.452
1983 Cruz TF, Gurd JW. Identification of intrinsic sialidase and sialoglycoprotein substrates in rat brain synaptic junctions Journal of Neurochemistry. 40: 1599-1604. PMID 6854322 DOI: 10.1111/J.1471-4159.1983.Tb08132.X  0.419
1983 Cruz TF, Gurd JW. Developmental changes in the biosynthesis of sialoglycoprotein substrates for intrinsic synaptic sialidase Journal of Neurochemistry. 40: 1487-1489. PMID 6834072 DOI: 10.1111/J.1471-4159.1983.Tb13595.X  0.357
1983 Gurd JW, Gordon-Weeks PR, Evans WH. Identification and localization of concanavalin A binding sites on isolated postsynaptic densities. Brain Research. 276: 141-6. PMID 6626993 DOI: 10.1016/0006-8993(83)90555-3  0.416
1983 Fu SC, Gurd JW. Developmental changes in the oligosaccharide composition of synaptic junctional glycoproteins. Journal of Neurochemistry. 41: 1726-34. PMID 6417275 DOI: 10.1111/J.1471-4159.1983.Tb00886.X  0.377
1983 Gurd JW, Bissoon N, Kelly PT. Synaptic junctional glycoproteins are phosphorylated by cyclic-AMP-dependent protein kinase Brain Research. 269: 287-296. PMID 6309321 DOI: 10.1016/0006-8993(83)90138-5  0.326
1982 Gurd JW, Gordon-Weeks P, Evans WH. Biochemical and morphological comparison of postsynaptic densities prepared from rat, hamster, and monkey brains by phase partitioning. Journal of Neurochemistry. 39: 1117-24. PMID 7119784 DOI: 10.1111/J.1471-4159.1982.Tb11504.X  0.396
1982 Gurd JW, Fu SC. Concanavalin A receptors associated with rat brain synaptic junctions are high mannose-type oligosaccharides. Journal of Neurochemistry. 39: 719-25. PMID 7097277 DOI: 10.1111/J.1471-4159.1982.Tb07951.X  0.395
1981 Freedman MS, Clark BD, Cruz TF, Gurd JW, Brown IR. Selective effects of LSD and hyperthemia on the synthesis of synaptic proteins and glycoproteins Brain Research. 207: 129-145. PMID 7470898 DOI: 10.1016/0006-8993(81)90683-1  0.409
1981 Wood JG, Byrd FI, Gurd JW. Lectin cytochemistry of carbohydrates on cell membranes of rat cerebellum Journal of Neurocytology. 10: 149-159. PMID 7310443 DOI: 10.1007/Bf01181750  0.332
1981 Fu SC, Cruz TF, Gurd JW. Development of synaptic glycoproteins: effect of postnatal age on the synthesis and concentration of synaptic membrane and synaptic junctional fucosyl and sialyl glycoproteins. Journal of Neurochemistry. 36: 1338-51. PMID 7264630 DOI: 10.1111/J.1471-4159.1981.Tb00571.X  0.451
1981 Cruz TF, Gurd JW. The effects of development on activity, specificity and endogenous substrates of synaptic membrane sialidase Bba - General Subjects. 675: 201-208. PMID 6168296 DOI: 10.1016/0304-4165(81)90227-0  0.396
1980 Gurd JW. Subcellular distribution and partial characterization of the three major classes of concanavalin A receptors associated with rat brain synaptic junctions Canadian Journal of Biochemistry. 58: 941-951. PMID 7459687  0.352
1980 McLaughlin BJ, Wood JG, Gurd JW. The localization of lectin binding sites during photoreceptor synaptogenesis in the chick retina Brain Research. 191: 345-357. PMID 7378765 DOI: 10.1016/0006-8993(80)91286-X  0.41
1980 Cruz TF, Gurd JW. An adaptation of the sodium periodate/sodium borotritide labeling procedure which allows the unambiguous identification of synaptic sialoglycoproteins Analytical Biochemistry. 108: 139-145. PMID 6257137 DOI: 10.1016/0003-2697(80)90703-4  0.391
1979 Gurd JW. Molecular and biosynthetic heterogeneity of fucosyl glycoproteins associated with rat brain synaptic junctions Bba - Biomembranes. 555: 221-229. PMID 476103 DOI: 10.1016/0005-2736(79)90162-7  0.438
1979 De Silva NS, Gurd JW, Schwartz C. Developmental alteration of rat brain synaptic membranes. Reaction of glycoproteins with plant lectins Brain Research. 165: 283-293. PMID 217493 DOI: 10.1016/0006-8993(79)90560-2  0.458
1978 Gurd JW. Biosynthesis of synaptic membranes. Incorporation of [3H]leucine into proteins and glycoproteins of rat brain synaptic plasma membranes Brain Research. 147: 201-204. PMID 77702 DOI: 10.1016/0006-8993(78)90789-8  0.426
1977 Gurd JW. Identification of lectin receptors associated with rat brain postsynaptic densities Brain Research. 126: 154-159. PMID 851888 DOI: 10.1016/0006-8993(77)90222-0  0.384
1977 Gurd JW. Synaptic plasma membrane glycoproteins: Molecular identification of lectin receptors Biochemistry. 16: 369-374. PMID 836792  0.328
1976 Gurd JW. Fractionation of rat brain acetylcholinesterase by lectin affinity chromatography Journal of Neurochemistry. 27: 1257-1259. PMID 12170618 DOI: 10.1111/J.1471-4159.1976.Tb00338.X  0.327
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