| Year |
Citation |
Score |
| 2012 |
Potet F, Lorinc AN, Chaigne S, Hopkins CR, Venkataraman R, Stepanovic SZ, Lewis LM, Days E, Sidorov VY, Engers DW, Zou B, Afshartous D, George AL, Campbell CM, Balser JR, et al. Identification and characterization of a compound that protects cardiac tissue from human Ether-Ã -go-go-related gene (hERG)-related drug-induced arrhythmias. The Journal of Biological Chemistry. 287: 39613-25. PMID 23033485 DOI: 10.1074/Jbc.M112.380162 |
0.371 |
|
| 2010 |
Nakajima T, Davies SS, Matafonova E, Potet F, Amarnath V, Tallman KA, Serwa RA, Porter NA, Balser JR, Kupershmidt S, Roberts LJ. Selective gamma-ketoaldehyde scavengers protect Nav1.5 from oxidant-induced inactivation. Journal of Molecular and Cellular Cardiology. 48: 352-9. PMID 19962379 DOI: 10.1016/J.Yjmcc.2009.11.016 |
0.456 |
|
| 2009 |
Yamagishi T, Xiong W, Kondratiev A, Vélez P, Méndez-Fitzwilliam A, Balser JR, Marbán E, Tomaselli GF. Novel molecular determinants in the pore region of sodium channels regulate local anesthetic binding. Molecular Pharmacology. 76: 861-71. PMID 19620257 DOI: 10.1124/Mol.109.055863 |
0.513 |
|
| 2009 |
Stepanovic SZ, Potet F, Petersen CI, Smith JA, Meiler J, Balser JR, Kupershmidt S. The evolutionarily conserved residue A653 plays a key role in HERG channel closing. The Journal of Physiology. 587: 2555-66. PMID 19406877 DOI: 10.1113/Jphysiol.2008.166694 |
0.44 |
|
| 2009 |
Potet F, Chagot B, Anghelescu M, Viswanathan PC, Stepanovic SZ, Kupershmidt S, Chazin WJ, Balser JR. Functional Interactions between Distinct Sodium Channel Cytoplasmic Domains through the Action of Calmodulin. The Journal of Biological Chemistry. 284: 8846-54. PMID 19171938 DOI: 10.1074/Jbc.M806871200 |
0.497 |
|
| 2009 |
Chagot B, Potet F, Balser JR, Chazin WJ. Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5. The Journal of Biological Chemistry. 284: 6436-45. PMID 19074138 DOI: 10.1074/Jbc.M807747200 |
0.457 |
|
| 2009 |
Potet F, Petersen CI, Boutaud O, Shuai W, Stepanovic SZ, Balser JR, Kupershmidt S. Genetic screening in C. elegans identifies rho-GTPase activating protein 6 as novel HERG regulator. Journal of Molecular and Cellular Cardiology. 46: 257-67. PMID 19038263 DOI: 10.1016/J.Yjmcc.2008.10.015 |
0.374 |
|
| 2009 |
Chagot B, Potet F, Balser J, Chazin W. 1H, 13C, and 15N Chemical Shift Assignments for the C-terminal EF-Hand domain of human cardiac sodium channel NaV1.5 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr16045 |
0.407 |
|
| 2007 |
Boyden PA, Davies SS, Viswanathan PC, Amarnath V, Balser JR, Roberts LJ. Potential role of isoketals formed via the isoprostane pathway of lipid peroxidation in ischemic arrhythmias. Journal of Cardiovascular Pharmacology. 50: 480-6. PMID 18030056 DOI: 10.1097/Fjc.0B013E31815A0564 |
0.352 |
|
| 2007 |
Nakajima T, Hayashi K, Viswanathan PC, Kim MY, Anghelescu M, Barksdale KA, Shuai W, Balser JR, Kupershmidt S. HERG is protected from pharmacological block by alpha-1,2-glucosyltransferase function. The Journal of Biological Chemistry. 282: 5506-13. PMID 17189275 DOI: 10.1074/Jbc.M605976200 |
0.366 |
|
| 2006 |
Viswanathan PC, Balser JR. Molecular basis of isolated cardiac conduction disease. Handbook of Experimental Pharmacology. 331-47. PMID 16610351 DOI: 10.1007/3-540-29715-4_13 |
0.448 |
|
| 2006 |
Shah VN, Wingo TL, Weiss KL, Williams CK, Balser JR, Chazin WJ. Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switch. Proceedings of the National Academy of Sciences of the United States of America. 103: 3592-7. PMID 16505387 DOI: 10.1073/Pnas.0507397103 |
0.708 |
|
| 2005 |
Fukuda K, Davies SS, Nakajima T, Ong BH, Kupershmidt S, Fessel J, Amarnath V, Anderson ME, Boyden PA, Viswanathan PC, Roberts LJ, Balser JR. Oxidative mediated lipid peroxidation recapitulates proarrhythmic effects on cardiac sodium channels. Circulation Research. 97: 1262-9. PMID 16284182 DOI: 10.1161/01.Res.0000195844.31466.E9 |
0.506 |
|
| 2005 |
Smits JP, Koopmann TT, Wilders R, Veldkamp MW, Opthof T, Bhuiyan ZA, Mannens MM, Balser JR, Tan HL, Bezzina CR, Wilde AA. A mutation in the human cardiac sodium channel (E161K) contributes to sick sinus syndrome, conduction disease and Brugada syndrome in two families. Journal of Molecular and Cellular Cardiology. 38: 969-81. PMID 15910881 DOI: 10.1016/J.Yjmcc.2005.02.024 |
0.429 |
|
| 2005 |
Fukuda K, Nakajima T, Viswanathan PC, Balser JR. Compound-specific Na+ channel pore conformational changes induced by local anaesthetics. The Journal of Physiology. 564: 21-31. PMID 15677685 DOI: 10.1113/Jphysiol.2004.081646 |
0.521 |
|
| 2004 |
Petersen CI, McFarland TR, Stepanovic SZ, Yang P, Reiner DJ, Hayashi K, George AL, Roden DM, Thomas JH, Balser JR. In vivo identification of genes that modify ether-a-go-go-related gene activity in Caenorhabditis elegans may also affect human cardiac arrhythmia. Proceedings of the National Academy of Sciences of the United States of America. 101: 11773-8. PMID 15280551 DOI: 10.1073/Pnas.0306005101 |
0.426 |
|
| 2004 |
Mullins FM, Stepanovic SZ, Gillani NB, George AL, Balser JR. Functional interaction between extracellular sodium, potassium and inactivation gating in HERG channels Journal of Physiology. 558: 729-744. PMID 15169846 DOI: 10.1113/Jphysiol.2004.065193 |
0.738 |
|
| 2004 |
Wingo TL, Shah VN, Anderson ME, Lybrand TP, Chazin WJ, Balser JR. An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability. Nature Structural & Molecular Biology. 11: 219-25. PMID 14981509 DOI: 10.1038/Nsmb737 |
0.726 |
|
| 2004 |
Viswanathan PC, Balser JR. Inherited sodium channelopathies: a continuum of channel dysfunction. Trends in Cardiovascular Medicine. 14: 28-35. PMID 14720472 DOI: 10.1016/J.Tcm.2003.10.001 |
0.531 |
|
| 2004 |
Balser JR. Biophysics of Normal and Abnormal Cardiac Sodium Channel Function Cardiac Electrophysiology: Fourth Edition. 77-87. DOI: 10.1016/B0-7216-0323-8/50012-9 |
0.368 |
|
| 2003 |
Kupershmidt S, Yang IC, Hayashi K, Wei J, Chanthaphaychith S, Petersen CI, Johns DC, George AL, Roden DM, Balser JR. The IKr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 2263-5. PMID 14525949 DOI: 10.1096/Fj.02-1057Fje |
0.367 |
|
| 2003 |
Viswanathan PC, Benson DW, Balser JR. A common SCN5A polymorphism modulates the biophysical effects of an SCN5A mutation. The Journal of Clinical Investigation. 111: 341-6. PMID 12569159 DOI: 10.1172/Jci16879 |
0.445 |
|
| 2002 |
Dzhura I, Wu Y, Colbran RJ, Corbin JD, Balser JR, Anderson ME. Cytoskeletal disrupting agents prevent calmodulin kinase, IQ domain and voltage-dependent facilitation of L-type Ca2+ channels. The Journal of Physiology. 545: 399-406. PMID 12456820 DOI: 10.1113/Jphysiol.2002.021881 |
0.397 |
|
| 2002 |
Mullins FM, Stepanovic SZ, Desai RR, George AL, Balser JR. Extracellular sodium interacts with the HERG channel at an outer pore site. The Journal of General Physiology. 120: 517-37. PMID 12356854 DOI: 10.1085/Jgp.20028589 |
0.756 |
|
| 2002 |
Kupershmidt S, Yang ICH, Sutherland M, Wells KS, Yang T, Yang P, Balser JR, Roden DM. Cardiac-enriched LIM domain protein fhl2 is required to generate IKs in a heterologous system Cardiovascular Research. 56: 93-103. PMID 12237170 DOI: 10.1016/S0008-6363(02)00498-4 |
0.486 |
|
| 2002 |
Balser JR. Inherited sodium channelopathies: models for acquired arrhythmias? American Journal of Physiology. Heart and Circulatory Physiology. 282: H1175-80. PMID 11893549 DOI: 10.1152/Ajpheart.00757.2001 |
0.498 |
|
| 2002 |
Roden DM, Balser JR, George AL, Anderson ME. Cardiac ion channels. Annual Review of Physiology. 64: 431-75. PMID 11826275 DOI: 10.1146/Annurev.Physiol.64.083101.145105 |
0.384 |
|
| 2002 |
Tan HL, Kupershmidt S, Zhang R, Stepanovic S, Roden DM, Wilde AA, Anderson ME, Balser JR. A calcium sensor in the sodium channel modulates cardiac excitability. Nature. 415: 442-7. PMID 11807557 DOI: 10.1038/415442A |
0.54 |
|
| 2002 |
Wang DW, Viswanathan PC, Balser JR, George AL, Benson DW. Clinical, genetic, and biophysical characterization of SCN5A mutations associated with atrioventricular conduction block. Circulation. 105: 341-6. PMID 11804990 DOI: 10.1161/Hc0302.102592 |
0.442 |
|
| 2001 |
Balser JR. Inherited sodium channelopathies: Novel therapeutic and proarrhythmic molecular mechanisms Trends in Cardiovascular Medicine. 11: 229-237. PMID 11673053 DOI: 10.1016/S1050-1738(01)00116-5 |
0.522 |
|
| 2001 |
Viswanathan PC, Bezzina CR, George AL, Roden DM, Wilde AA, Balser JR. Gating-dependent mechanisms for flecainide action in SCN5A-linked arrhythmia syndromes. Circulation. 104: 1200-5. PMID 11535580 DOI: 10.1161/Hc3501.093797 |
0.499 |
|
| 2001 |
Johnson J.P. J, Balser JR, Bennett PB. A novel extracellular calcium sensing mechanism in voltage-gated potassium ion channels Journal of Neuroscience. 21: 4143-4153. PMID 11404399 DOI: 10.1523/Jneurosci.21-12-04143.2001 |
0.543 |
|
| 2001 |
Balser JR. The cardiac sodium channel: Gating function and molecular pharmacology Journal of Molecular and Cellular Cardiology. 33: 599-613. PMID 11273715 DOI: 10.1006/Jmcc.2000.1346 |
0.529 |
|
| 2001 |
Tan HL, Bink-Boelkens MT, Bezzina CR, Viswanathan PC, Beaufort-Krol GC, van Tintelen PJ, van den Berg MP, Wilde AA, Balser JR. A sodium-channel mutation causes isolated cardiac conduction disease. Nature. 409: 1043-7. PMID 11234013 DOI: 10.1038/35059090 |
0.486 |
|
| 2000 |
Numaguchi H, Mullins FM, Johnson JP, Johns DC, Po SS, Yang IC, Tomaselli GF, Balser JR. Probing the interaction between inactivation gating and Dd-sotalol block of HERG. Circulation Research. 87: 1012-8. PMID 11090546 DOI: 10.1161/01.Res.87.11.1012 |
0.764 |
|
| 2000 |
Ong BH, Tomaselli GF, Balser JR. A structural rearrangement in the sodium channel pore linked to slow inactivation and use dependence Journal of General Physiology. 116: 653-661. PMID 11055994 DOI: 10.1085/Jgp.116.5.653 |
0.478 |
|
| 2000 |
Wang DW, Makita N, Kitabatake A, Balser JR, George AL. Enhanced Na(+) channel intermediate inactivation in Brugada syndrome Circulation Research. 87. PMID 11029409 DOI: 10.1161/01.Res.87.8.E37 |
0.507 |
|
| 2000 |
Veldkamp MW, Viswanathan PC, Bezzina C, Baartscheer A, Wilde AA, Balser JR. Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel. Circulation Research. 86: E91-7. PMID 10807877 DOI: 10.1161/01.Res.86.9.E91 |
0.51 |
|
| 2000 |
Kambouris NG, Nuss HB, Johns DC, Marbán E, Tomaselli GF, Balser JR. A revised view of cardiac sodium channel "blockade" in the long-QT syndrome. The Journal of Clinical Investigation. 105: 1133-40. PMID 10772658 DOI: 10.1172/Jci9212 |
0.568 |
|
| 2000 |
Numaguchi H, Johnson JP, Petersen CI, Balser JR. A sensitive mechanism for cation modulation of potassium current Nature Neuroscience. 3: 429-430. PMID 10769379 DOI: 10.1038/74793 |
0.45 |
|
| 2000 |
Chen Z, Ong BH, Kambouris NG, Marbán E, Tomaselli GF, Balser JR. Lidocaine induces a slow inactivated state in rat skeletal muscle sodium channels. The Journal of Physiology. 524: 37-49. PMID 10747182 DOI: 10.1111/J.1469-7793.2000.T01-1-00037.X |
0.547 |
|
| 2000 |
Dzhura I, Wu Y, Colbran RJ, Balser JR, Anderson ME. Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nature Cell Biology. 2: 173-7. PMID 10707089 DOI: 10.1038/35004052 |
0.447 |
|
| 2000 |
Nuss HB, Kambouris NG, Marbán E, Tomaselli GF, Balser JR. Isoform-specific lidocaine block of sodium channels explained by differences in gating. Biophysical Journal. 78: 200-10. PMID 10620286 DOI: 10.1016/S0006-3495(00)76585-4 |
0.484 |
|
| 1999 |
Roden DM, Balser JR. A plethora of mechanisms in the HERG-related long QT syndrome: Genetics meets electrophysiology Cardiovascular Research. 44: 242-246. PMID 10690299 DOI: 10.1016/S0008-6363(99)00224-2 |
0.407 |
|
| 1999 |
Johnson JP, Balser JR, Bennett PB. Enhancement of HERG K+ currents by Cd2+ destabilization of the inactivated state Biophysical Journal. 77: 2534-2541. PMID 10545354 DOI: 10.1016/S0006-3495(99)77088-8 |
0.404 |
|
| 1999 |
Balser JR. Structure and function of the cardiac sodium channels Cardiovascular Research. 42: 327-338. PMID 10533571 DOI: 10.1016/S0008-6363(99)00031-0 |
0.533 |
|
| 1999 |
Balser JR. Sodium 'channelopathies' and sudden death: Must you be so sensitive? Circulation Research. 85: 872-874. PMID 10532957 DOI: 10.1161/01.Res.85.9.872 |
0.539 |
|
| 1999 |
Bénitah JP, Chen Z, Balser JR, Tomaselli GF, Marbán E. Molecular dynamics of the sodium channel pore vary with gating: interactions between P-segment motions and inactivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1577-85. PMID 10024345 |
0.351 |
|
| 1998 |
Balser JR, Martinez EA, Winters BD, Perdue PW, Clarke AW, Huang W, Tomaselli GF, Dorman T, Campbell K, Lipsett P, Breslow MJ, Rosenfeld BA. Beta-adrenergic blockade accelerates conversion of postoperative supraventricular tachyarrhythmias. Anesthesiology. 89: 1052-9. PMID 9821992 DOI: 10.1097/00000542-199811000-00004 |
0.312 |
|
| 1998 |
Kambouris NG, Hastings LA, Stepanovic S, Marban E, Tomaselli GF, Balser JR. Mechanistic link between lidocaine block and inactivation probed by outer pore mutations in the rat micro1 skeletal muscle sodium channel. The Journal of Physiology. 512: 693-705. PMID 9769414 DOI: 10.1111/J.1469-7793.1998.693Bd.X |
0.492 |
|
| 1998 |
Pu J, Balser JR, Boyden PA. Lidocaine action on Na+ currents in ventricular myocytes from the epicardial border zone of the infarcted heart Circulation Research. 83: 431-440. PMID 9721700 DOI: 10.1161/01.Res.83.4.431 |
0.512 |
|
| 1998 |
Kambouris NG, Nuss HB, Johns DC, Tomaselli GF, Marban E, Balser JR. Phenotypic characterization of a novel long-QT syndrome mutation (R1623Q) in the cardiac sodium channel. Circulation. 97: 640-4. PMID 9495298 DOI: 10.1161/01.Cir.97.7.640 |
0.473 |
|
| 1998 |
Balser JR. The molecular interaction between local anesthetic/antiarrhythmic agents and voltage-gated sodium channels Trends in Cardiovascular Medicine. 8: 83-88. DOI: 10.1016/S1050-1738(97)00124-2 |
0.511 |
|
| 1997 |
Pérez-GarcÃa MT, Chiamvimonvat N, Ranjan R, Balser JR, Tomaselli GF, Marban E. Mechanisms of sodium/calcium selectivity in sodium channels probed by cysteine mutagenesis and sulfhydryl modification. Biophysical Journal. 72: 989-96. PMID 9138597 DOI: 10.1016/S0006-3495(97)78751-4 |
0.507 |
|
| 1997 |
Bénitah J, Balser JR, Marban E, Tomaselli GF. Proton inhibition of sodium channels: mechanism of gating shifts and reduced conductance. The Journal of Membrane Biology. 155: 121-31. PMID 9049106 DOI: 10.1007/s002329900164 |
0.4 |
|
| 1997 |
Balser J, Clarke A, Winters B, Martinez E, Perdue P, Rosenfeld &. A130 BETA BLOCKADE IS SUPERIOR TO CALCIUM CHANNEL BLOCKADE FOR CONVERSION OF POSTOPERATIVE SVT Anesthesiology. 87: 130A. DOI: 10.1097/00000542-199709001-00130 |
0.382 |
|
| 1996 |
Balser JR, Nuss HB, Orias DW, Johns DC, Marban E, Tomaselli GF, Lawrence JH. Local anesthetics as effectors of allosteric gating. Lidocaine effects on inactivation-deficient rat skeletal muscle Na channels. The Journal of Clinical Investigation. 98: 2874-86. PMID 8981936 DOI: 10.1172/Jci119116 |
0.533 |
|
| 1996 |
Lawrence JH, Orias DW, Balser JR, Nuss HB, Tomaselli GF, O'Rourke B, Marban E. Single-channel analysis of inactivation-defective rat skeletal muscle sodium channels containing the F1304Q mutation. Biophysical Journal. 71: 1285-94. PMID 8874003 DOI: 10.1016/S0006-3495(96)79329-3 |
0.496 |
|
| 1996 |
Balser JR, Nuss HB, Chiamvimonvat N, Pérez-GarcÃa MT, Marban E, Tomaselli GF. External pore residue mediates slow inactivation in mu 1 rat skeletal muscle sodium channels. The Journal of Physiology. 494: 431-42. PMID 8842002 DOI: 10.1113/Jphysiol.1996.Sp021503 |
0.419 |
|
| 1996 |
Nuss HB, Balser JR, Orias DW, Lawrence JH, Tomaselli GF, Marban E. Coupling between fast and slow inactivation revealed by analysis of a point mutation (F1304Q) in mu 1 rat skeletal muscle sodium channels. The Journal of Physiology. 494: 411-29. PMID 8842001 |
0.418 |
|
| 1996 |
Balser JR, Nuss HB, Romashko DN, Marban E, Tomaselli GF. Functional consequences of lidocaine binding to slow-inactivated sodium channels. The Journal of General Physiology. 107: 643-58. PMID 8740377 DOI: 10.1085/jgp.107.5.643 |
0.405 |
|
| 1995 |
Tomaselli GF, Chiamvimonvat N, Nuss HB, Balser JR, Perez-Garcia MT, Ruo Hui Xu, Orias DW, Backx PH, Marban E. A mutation in the pore of the sodium channel alters gating Biophysical Journal. 68: 1814-1827. PMID 7612823 DOI: 10.1016/S0006-3495(95)80358-9 |
0.438 |
|
| 1991 |
Balser JR, Roden DM, Bennett PB. Single inward rectifier potassium channels in guinea pig ventricular myocytes. Effects of quinidine Biophysical Journal. 59: 150-161. PMID 2015380 DOI: 10.1016/S0006-3495(91)82207-X |
0.501 |
|
| 1991 |
Balser JR, Bennett PB, Hondeghem LM, Roden DM. Suppression of time-dependent outward current in guinea pig ventricular myocytes: Actions of quinidine and amiodarone Circulation Research. 69: 519-529. PMID 1860189 DOI: 10.1161/01.Res.69.2.519 |
0.436 |
|
| 1990 |
Balser JR, Roden DM, Bennett PB. Global parameter optimization for cardiac potassium channel gating models Biophysical Journal. 57: 433-444. PMID 2306494 DOI: 10.1016/S0006-3495(90)82560-1 |
0.359 |
|
| 1990 |
Balser JR, Bennett PB, Roden DM. Time-dependent outward current in guinea pig ventricular myocytes gating kinetics of the delayed rectifier Journal of General Physiology. 96: 835-863. PMID 2258717 DOI: 10.1085/Jgp.96.4.835 |
0.449 |
|
| 1988 |
Roden DM, Bennett PB, Snyders DJ, Balser JR, Hondeghem LM. Quinidine delays I(K) activation in guinea pig ventricular myocytes Circulation Research. 62: 1055-1058. PMID 2452034 DOI: 10.1161/01.Res.62.5.1055 |
0.348 |
|
| Show low-probability matches. |