Kirill Gorshkov - Publications

Affiliations: 
United States, Independence, KS, United States 
Area:
Neurodegeneration, Synaptic Plasticity, Learning and Memory

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Gorshkov K, Vasquez DM, Chiem K, Ye C, Tran BN, de la Torre JC, Moran T, Chen CZ, Martinez-Sobrido L, Zheng W. A SARS-CoV-2 nucleocapsid protein TR-FRET assay amenable to high-throughput screening. Biorxiv : the Preprint Server For Biology. PMID 34268508 DOI: 10.1101/2021.07.03.450938  0.56
2021 Brooks BM, Pradhan M, Cheng YS, Gorshkov K, Farkhondeh A, Chen CZ, Beers J, Liu C, Baumgaertel K, Rodems S, Zheng W. Generation of an induced pluripotent stem cell line (TRNDi031-A) from a patient with Alagille syndrome type 1 carrying a heterozygous p. C312X (c. 936 T > A) mutation in JAGGED-1. Stem Cell Research. 54: 102447. PMID 34198154 DOI: 10.1016/j.scr.2021.102447  0.56
2021 Brooks BM, Yeh CD, Beers J, Liu C, Cheng YS, Gorshkov K, Zou J, Zheng W, Chen CZ. Generation of an induced pluripotent stem cell line (TRNDi030-A) from a patient with Farber disease carrying a homozygous p. Y36C (c. 107 A>G) mutation in ASAH1. Stem Cell Research. 53: 102387. PMID 34088014 DOI: 10.1016/j.scr.2021.102387  0.56
2021 Ilnytska O, Lai K, Gorshkov K, Schultz ML, Tran BN, Jeziorek M, Kunkel TJ, Azaria RD, McLoughlin HS, Waghalter M, Xu Y, Schlame M, Altan-Bonnet N, Zheng W, Lieberman AP, et al. Enrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduces cholesterol storage. The Journal of Biological Chemistry. 100813. PMID 34023384 DOI: 10.1016/j.jbc.2021.100813  0.56
2020 Yang S, Gorshkov K, Lee EM, Xu M, Cheng YS, Sun N, Soheilian F, de Val N, Ming G, Song H, Tang H, Zheng W. Zika Virus-Induced Neuronal Apoptosis via Increased Mitochondrial Fragmentation. Frontiers in Microbiology. 11: 598203. PMID 33424801 DOI: 10.3389/fmicb.2020.598203  0.56
2020 Xu J, Ji L, Liang Y, Wan Z, Zheng W, Song X, Gorshkov K, Sun Q, Lin H, Zheng X, Chen J, Jin RA, Liang X, Cai X. CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1. Signal Transduction and Targeted Therapy. 5: 298. PMID 33361760 DOI: 10.1038/s41392-020-00375-5  0.6
2020 Gorshkov K, Chen CZ, Bostwick R, Rasmussen L, Tran BN, Cheng YS, Xu M, Pradhan M, Henderson M, Zhu W, Oh E, Susumu K, Wolak M, Shamim K, Huang W, et al. The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules. Acs Infectious Diseases. PMID 33346633 DOI: 10.1021/acsinfecdis.0c00349  0.56
2020 Gorshkov K, Chen CZ, Xu M, Carlos de la Torre J, Martinez-Sobrido L, Moran T, Zheng W. Development of a High-Throughput Homogeneous AlphaLISA Drug Screening Assay for the Detection of SARS-CoV-2 Nucleocapsid. Acs Pharmacology & Translational Science. 3: 1233-1241. PMID 33330840 DOI: 10.1021/acsptsci.0c00122  0.56
2020 Chen CZ, Xu M, Pradhan M, Gorshkov K, Petersen JD, Straus MR, Zhu W, Shinn P, Guo H, Shen M, Klumpp-Thomas C, Michael SG, Zimmerberg J, Zheng W, Whittaker GR. Identifying SARS-CoV-2 Entry Inhibitors through Drug Repurposing Screens of SARS-S and MERS-S Pseudotyped Particles. Acs Pharmacology & Translational Science. 3: 1165-1175. PMID 33330839 DOI: 10.1021/acsptsci.0c00112  0.56
2020 Xu J, Wan Z, Tang M, Lin Z, Jiang S, Ji L, Gorshkov K, Mao Q, Xia S, Cen D, Zheng J, Liang X, Cai X. N-methyladenosine-modified CircRNA-SORE sustains sorafenib resistance in hepatocellular carcinoma by regulating β-catenin signaling. Molecular Cancer. 19: 163. PMID 33222692 DOI: 10.1186/s12943-020-01281-8  0.6
2020 Gorshkov K, Susumu K, Chen J, Xu M, Pradhan M, Zhu W, Hu X, Breger JC, Wolak M, Oh E. Quantum Dot-Conjugated SARS-CoV-2 Spike Pseudo-Virions Enable Tracking of Angiotensin Converting Enzyme 2 Binding and Endocytosis. Acs Nano. PMID 32845122 DOI: 10.1021/Acsnano.0C05975  0.56
2020 Chen CZ, Xu M, Pradhan M, Gorshkov K, Petersen J, Straus MR, Zhu W, Shinn P, Guo H, Shen M, Klumpp-Thomas C, Michael SG, Zimmerberg J, Zheng W, Whittaker GR. Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles. Biorxiv : the Preprint Server For Biology. PMID 32839777 DOI: 10.1101/2020.07.10.197988  0.56
2020 Gorshkov K, Chen CZ, de la Torre JC, Martinez-Sobrido L, Moran T, Zheng W. Development of a high-throughput homogeneous AlphaLISA drug screening assay for the detection of SARS-CoV-2 Nucleocapsid. Biorxiv : the Preprint Server For Biology. PMID 32839774 DOI: 10.1101/2020.08.20.258129  0.56
2020 Shyr ZA, Gorshkov K, Chen CZ, Zheng W. . The Journal of Pharmacology and Experimental Therapeutics. PMID 32723801 DOI: 10.1124/Jpet.120.000123  0.56
2020 Zhu W, Chen CZ, Gorshkov K, Xu M, Lo DC, Zheng W. RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery. Slas Discovery : Advancing Life Sciences R & D. 2472555220942123. PMID 32660307 DOI: 10.1177/2472555220942123  0.56
2020 Gorshkov K, Pradhan M, Xu M, Yang S, Lee EM, Chen CZ, Shen M, Zheng W. Cell-based no-wash fluorescence assays for compound screens using a fluorescence cytometry plate reader. The Journal of Pharmacology and Experimental Therapeutics. PMID 32532853 DOI: 10.1124/Jpet.120.265207  0.56
2020 Brimacombe KR, Zhao T, Eastman RT, Hu X, Wang K, Backus M, Baljinnyam B, Chen CZ, Chen L, Eicher T, Ferrer M, Fu Y, Gorshkov K, Guo H, Hanson QM, et al. An OpenData portal to share COVID-19 drug repurposing data in real time. Biorxiv : the Preprint Server For Biology. PMID 32511420 DOI: 10.1101/2020.06.04.135046  0.56
2019 Gorshkov K, Wang AQ, Sun W, Fisher E, Frigeni M, Singleton M, Thorne N, Class B, Huang W, Longo N, Do MT, Ottinger EA, Xu X, Zheng W. Phosphocyclocreatine is the dominant form of cyclocreatine in control and creatine transporter deficiency patient fibroblasts. Pharmacology Research & Perspectives. 7: e00525. PMID 31859463 DOI: 10.1002/Prp2.525  0.56
2019 Almeciga-Diaz CJ, Hidalgo OA, Olarte-Avellaneda S, Rodriguez-Lopez A, Guzman E, Garzón R, Pimentel-Vera LN, Puentes-Tellez MA, Rojas-Rodriguez AF, Gorshkov K, Li R, Zheng W. Identification of ezetimibe and pranlukast as pharmacological chaperones for treatment of the rare disease Mucopolysaccharidosis type IVA. Journal of Medicinal Chemistry. PMID 31188588 DOI: 10.1021/Acs.Jmedchem.9B00428  0.56
2019 Farkhondeh A, Li R, Gorshkov K, Chen KG, Might M, Rodems S, Lo DC, Zheng W. Induced pluripotent stem cells for neural drug discovery. Drug Discovery Today. PMID 30664937 DOI: 10.1016/J.Drudis.2019.01.007  0.56
2018 Gorshkov K, Shiryaev SA, Fertel S, Lin YW, Huang CT, Pinto A, Farhy C, Strongin AY, Zheng W, Terskikh AV. Zika Virus: Origins, Pathological Action, and Treatment Strategies. Frontiers in Microbiology. 9: 3252. PMID 30666246 DOI: 10.3389/Fmicb.2018.03252  0.56
2018 Gorshkov K, Sima N, Sun W, Lu B, Huang W, Travers J, Klumpp-Thomas C, Michael SG, Xu T, Huang R, Lee EM, Cheng X, Zheng W. Quantitative Chemotherapeutic Profiling of Gynecologic Cancer Cell Lines Using Approved Drugs and Bioactive Compounds. Translational Oncology. 12: 441-452. PMID 30576957 DOI: 10.1016/J.Tranon.2018.11.016  0.56
2018 Vu M, Li R, Baskfield A, Lu B, Farkhondeh A, Gorshkov K, Motabar O, Beers J, Chen G, Zou J, Espejo-Mojica AJ, Rodríguez-López A, Alméciga-Díaz CJ, Barrera LA, Jiang X, et al. Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease. Orphanet Journal of Rare Diseases. 13: 152. PMID 30220252 DOI: 10.1186/S13023-018-0886-3  0.56
2018 Gorshkov K, Chen CZ, Marshall RE, Mihatov N, Choi Y, Nguyen DT, Southall N, Chen K, Park JK, Zheng W. Advancing precision medicine with personalized drug screening. Drug Discovery Today. PMID 30125678 DOI: 10.1016/J.Drudis.2018.08.010  0.56
2018 Sima N, Sun W, Gorshkov K, Shen M, Huang W, Zhu W, Xie X, Zheng W, Cheng X. Small Molecules Identified from a Quantitative Drug Combinational Screen Resensitize Cisplatin's Response in Drug-Resistant Ovarian Cancer Cells. Translational Oncology. 11: 1053-1064. PMID 29982103 DOI: 10.1016/J.Tranon.2018.06.002  0.56
2018 Yang S, Xu M, Lee EM, Gorshkov K, Shiryaev SA, He S, Sun W, Cheng YS, Hu X, Tharappel AM, Lu B, Pinto A, Farhy C, Huang CT, Zhang Z, et al. Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry. Cell Discovery. 4: 31. PMID 29872540 DOI: 10.1038/S41421-018-0034-1  0.56
2018 Oldach LM, Gorshkov K, Mills WT, Zhang J, Meffert MK. A Biosensor for MAPK-Dependent Lin28 Signaling. Molecular Biology of the Cell. PMID 29540527 DOI: 10.1091/Mbc.E17-08-0500  0.88
2018 Gorshkov K, Aguisanda F, Thorne N, Zheng W. Astrocytes as targets for drug discovery. Drug Discovery Today. PMID 29317338 DOI: 10.1016/J.Drudis.2018.01.011  0.56
2017 Gorshkov K, Mehta S, Ramamurthy S, Ronnett GV, Zhou FQ, Zhang J. AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons. Nature Chemical Biology. PMID 28192412 DOI: 10.1038/Nchembio.2298  0.88
2015 Head SA, Shi W, Zhao L, Gorshkov K, Pasunooti K, Chen Y, Deng Z, Li RJ, Shim JS, Tan W, Hartung T, Zhang J, Zhao Y, Colombini M, Liu JO. Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26655341 DOI: 10.1073/Pnas.1512867112  0.6
2015 Miyamoto T, Rho E, Sample V, Akano H, Magari M, Ueno T, Gorshkov K, Chen M, Tokumitsu H, Zhang J, Inoue T. Compartmentalized AMPK signaling illuminated by genetically encoded molecular sensors and actuators. Cell Reports. 11: 657-70. PMID 25892241 DOI: 10.1016/J.Celrep.2015.03.057  0.6
2015 Sample V, Ramamurthy S, Gorshkov K, Ronnett GV, Zhang J. Polarized activities of AMPK and BRSK in primary hippocampal neurons. Molecular Biology of the Cell. 26: 1935-46. PMID 25788287 DOI: 10.1091/Mbc.E14-02-0764  0.6
2014 Gorshkov K, Zhang J. Visualization of cyclic nucleotide dynamics in neurons. Frontiers in Cellular Neuroscience. 8: 395. PMID 25538560 DOI: 10.3389/Fncel.2014.00395  0.88
2014 Mehta S, Aye-Han NN, Ganesan A, Oldach L, Gorshkov K, Zhang J. Calmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin. Elife. 3: e03765. PMID 25056880 DOI: 10.7554/Elife.03765  0.6
2014 Mehta S, Aye-Han N, Ganesan A, Oldach L, Gorshkov K, Zhang J. Author response: Calmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin Elife. DOI: 10.7554/Elife.03765.018  0.88
2013 Filaretov V, Gorshkov K. Topological analysis of active networks containing pathological mirror elements 2013 Ieee 33rd International Scientific Conference Electronics and Nanotechnology, Elnano 2013 - Conference Proceedings. 460-464. DOI: 10.1109/ELNANO.2013.6552078  0.01
2012 Hua Y, Gorshkov K, Yang Y, Wang W, Zhang N, Hughes DP. Slow down to stay alive: HER4 protects against cellular stress and confers chemoresistance in neuroblastoma. Cancer. 118: 5140-54. PMID 22415601 DOI: 10.1002/Cncr.27496  0.6
2012 Filaretov V, Gorshkov K, Mikheenko A. A circuit synthesis technique based on network determinant expansion 2012 International Conference On Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design, Smacd 2012. 293-296. DOI: 10.1109/SMACD.2012.6339397  0.01
2011 Filaretov V, Gorshkov K. The generalization of the extra element theorem for symbolic circuit tolerance analysis Journal of Electrical and Computer Engineering. DOI: 10.1155/2011/652706  0.01
2008 Filaretov V, Gorshkov K. Transconductance realization of block-diagrams of electronic networks Icses'08 - Icses 2008 International Conference On Signals and Electronic Systems, Proceedings. 261-264. DOI: 10.1109/ICSES.2008.4673410  0.01
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