Robert J. DeLorenzo, M.D., Ph.D. - Publications

Affiliations: 
Pharmacology and Toxicology Virginia Commonwealth University School of Medicine, Richmond, VA 
Area:
Epilepsy, calcium signaling, neural plasticity

201 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Deshpande LS, DeLorenzo RJ. Novel therapeutics for treating organophosphate-induced status epilepticus co-morbidities, based on changes in calcium homeostasis. Neurobiology of Disease. PMID 30872159 DOI: 10.1016/j.nbd.2019.03.006  1
2018 Phillips KF, Deshpande LS, DeLorenzo RJ. Hypothermia Reduces Mortality, Prevents the Calcium Plateau, and Is Neuroprotective Following Status Epilepticus in Rats. Frontiers in Neurology. 9: 438. PMID 29942282 DOI: 10.3389/fneur.2018.00438  1
2016 Deshpande LS, Blair RE, Phillips KF, DeLorenzo RJ. Role of the calcium plateau in neuronal injury and behavioral morbidities following organophosphate intoxication. Annals of the New York Academy of Sciences. PMID 27327161 DOI: 10.1111/nyas.13122  1
2016 Deshpande LS, Blair RE, Huang BA, Phillips KF, DeLorenzo RJ. Pharmacological blockade of the calcium plateau provides neuroprotection following organophosphate paraoxon induced status epilepticus in rats. Neurotoxicology and Teratology. PMID 27224207 DOI: 10.1016/j.ntt.2016.05.002  1
2015 Blair RE, Deshpande LS, DeLorenzo RJ. Cannabinoids: is there a potential treatment role in epilepsy? Expert Opinion On Pharmacotherapy. 16: 1911-4. PMID 26234319 DOI: 10.1517/14656566.2015.1074181  1
2015 Blair RE, Deshpande LS, DeLorenzo RJ. Endocannabinoids and epilepsy Cannabinoids in Neurologic and Mental Disease. 125-172. DOI: 10.1016/B978-0-12-417041-4.00006-0  1
2014 Deshpande LS, Phillips K, Huang B, DeLorenzo RJ. Chronic behavioral and cognitive deficits in a rat survival model of paraoxon toxicity. Neurotoxicology. 44: 352-7. PMID 25172410 DOI: 10.1016/j.neuro.2014.08.008  1
2014 Deshpande LS, Carter DS, Phillips KF, Blair RE, DeLorenzo RJ. Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication. Neurotoxicology. 44: 17-26. PMID 24785379 DOI: 10.1016/j.neuro.2014.04.006  1
2014 Deshpande LS, Delorenzo RJ. Mechanisms of levetiracetam in the control of status epilepticus and epilepsy. Frontiers in Neurology. 5: 11. PMID 24550884 DOI: 10.3389/fneur.2014.00011  1
2013 Phillips KF, Deshpande LS, DeLorenzo RJ. Hypothermia reduces calcium entry via the N-methyl-D-aspartate and ryanodine receptors in cultured hippocampal neurons. European Journal of Pharmacology. 698: 186-92. PMID 23085028 DOI: 10.1016/j.ejphar.2012.10.010  1
2012 Sayers KW, Nguyen PT, Blair RE, Sim-Selley LJ, DeLorenzo RJ. Statistical parametric mapping reveals regional alterations in cannabinoid CB1 receptor distribution and G-protein activation in the 3D reconstructed epileptic rat brain. Epilepsia. 53: 897-907. PMID 22509801 DOI: 10.1111/j.1528-1167.2012.03460.x  1
2011 Deshpande LS, Blair RE, DeLorenzo RJ. Prolonged cannabinoid exposure alters GABA(A) receptor mediated synaptic function in cultured hippocampal neurons. Experimental Neurology. 229: 264-73. PMID 21324315 DOI: 10.1016/j.expneurol.2011.02.007  1
2011 Carter DS, Deshpande LS, Rafiq A, Sombati S, DeLorenzo RJ. Characterization of spontaneous recurrent epileptiform discharges in hippocampal-entorhinal cortical slices prepared from chronic epileptic animals. Seizure. 20: 218-24. PMID 21168348 DOI: 10.1016/j.seizure.2010.11.022  1
2011 Ziobro JM, Deshpande LS, Delorenzo RJ. An organotypic hippocampal slice culture model of excitotoxic injury induced spontaneous recurrent epileptiform discharges. Brain Research. 1371: 110-20. PMID 21111720 DOI: 10.1016/j.brainres.2010.11.065  1
2011 Deshpande LS, DeLorenzo RJ. Acetaminophen inhibits status epilepticus in cultured hippocampal neurons. Neuroreport. 22: 15-8. PMID 21037491 DOI: 10.1097/WNR.0b013e3283413231  1
2010 Nagarkatti N, Deshpande LS, Carter DS, DeLorenzo RJ. Dantrolene inhibits the calcium plateau and prevents the development of spontaneous recurrent epileptiform discharges following in vitro status epilepticus. The European Journal of Neuroscience. 32: 80-8. PMID 20597971 DOI: 10.1111/j.1460-9568.2010.07262.x  1
2010 Deshpande LS, Carter DS, Blair RE, DeLorenzo RJ. Development of a prolonged calcium plateau in hippocampal neurons in rats surviving status epilepticus induced by the organophosphate diisopropylfluorophosphate. Toxicological Sciences : An Official Journal of the Society of Toxicology. 116: 623-31. PMID 20498005 DOI: 10.1093/toxsci/kfq157  1
2009 Blair RE, Deshpande LS, Sombati S, Elphick MR, Martin BR, DeLorenzo RJ. Prolonged exposure to WIN55,212-2 causes downregulation of the CB1 receptor and the development of tolerance to its anticonvulsant effects in the hippocampal neuronal culture model of acquired epilepsy. Neuropharmacology. 57: 208-18. PMID 19540252 DOI: 10.1016/j.neuropharm.2009.06.007  1
2009 Nagarkatti N, Deshpande LS, DeLorenzo RJ. Development of the calcium plateau following status epilepticus: role of calcium in epileptogenesis. Expert Review of Neurotherapeutics. 9: 813-24. PMID 19496685 DOI: 10.1586/ern.09.21  1
2009 Blair RE, Deshpande LS, Holbert WH, Churn SB, DeLorenzo RJ. Age-dependent mortality in the pilocarpine model of status epilepticus. Neuroscience Letters. 453: 233-7. PMID 19429042 DOI: 10.1016/j.neulet.2009.02.035  1
2009 Falenski KW, Carter DS, Harrison AJ, Martin BR, Blair RE, DeLorenzo RJ. Temporal characterization of changes in hippocampal cannabinoid CB(1) receptor expression following pilocarpine-induced status epilepticus. Brain Research. 1262: 64-72. PMID 19368833 DOI: 10.1016/j.brainres.2009.01.036  1
2009 DeLorenzo RJ, Kirmani B, Deshpande LS, Jakkampudi V, Towne AR, Waterhouse E, Garnett L, Ramakrishnan V. Comparisons of the mortality and clinical presentations of status epilepticus in private practice community and university hospital settings in Richmond, Virginia. Seizure. 18: 405-11. PMID 19324574 DOI: 10.1016/j.seizure.2009.02.005  1
2008 Deshpande LS, Sun DA, Sombati S, Baranova A, Wilson MS, Attkisson E, Hamm RJ, DeLorenzo RJ. Alterations in neuronal calcium levels are associated with cognitive deficits after traumatic brain injury. Neuroscience Letters. 441: 115-9. PMID 18583041 DOI: 10.1016/j.neulet.2008.05.113  1
2008 Blair RE, Sombati S, Churn SB, Delorenzo RJ. Epileptogenesis causes an N-methyl-d-aspartate receptor/Ca2+-dependent decrease in Ca2+/calmodulin-dependent protein kinase II activity in a hippocampal neuronal culture model of spontaneous recurrent epileptiform discharges. European Journal of Pharmacology. 588: 64-71. PMID 18495112 DOI: 10.1016/j.ejphar.2008.04.021  1
2008 Deshpande LS, Nagarkatti N, Ziobro JM, Sombati S, DeLorenzo RJ. Carisbamate prevents the development and expression of spontaneous recurrent epileptiform discharges and is neuroprotective in cultured hippocampal neurons. Epilepsia. 49: 1795-802. PMID 18494784 DOI: 10.1111/j.1528-1167.2008.01667.x  1
2008 Nagarkatti N, Deshpande LS, DeLorenzo RJ. Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture. Neuroscience Letters. 436: 289-93. PMID 18406528 DOI: 10.1016/j.neulet.2008.02.076  1
2008 Carter DS, Harrison AJ, Falenski KW, Blair RE, DeLorenzo RJ. Long-term decrease in calbindin-D28K expression in the hippocampus of epileptic rats following pilocarpine-induced status epilepticus. Epilepsy Research. 79: 213-23. PMID 18394865 DOI: 10.1016/j.eplepsyres.2008.02.006  1
2008 Sun DA, Deshpande LS, Sombati S, Baranova A, Wilson MS, Hamm RJ, DeLorenzo RJ. Traumatic brain injury causes a long-lasting calcium (Ca2+)-plateau of elevated intracellular Ca levels and altered Ca2+ homeostatic mechanisms in hippocampal neurons surviving brain injury. The European Journal of Neuroscience. 27: 1659-72. PMID 18371074 DOI: 10.1111/j.1460-9568.2008.06156.x  1
2008 Deshpande LS, Nagarkatti N, Sombati S, DeLorenzo RJ. The novel antiepileptic drug carisbamate (RWJ 333369) is effective in inhibiting spontaneous recurrent seizure discharges and blocking sustained repetitive firing in cultured hippocampal neurons. Epilepsy Research. 79: 158-65. PMID 18353614 DOI: 10.1016/j.eplepsyres.2008.01.002  1
2008 Deshpande LS, Lou JK, Mian A, Blair RE, Sombati S, Attkisson E, DeLorenzo RJ. Time course and mechanism of hippocampal neuronal death in an in vitro model of status epilepticus: role of NMDA receptor activation and NMDA dependent calcium entry. European Journal of Pharmacology. 583: 73-83. PMID 18289526 DOI: 10.1016/j.ejphar.2008.01.025  1
2007 Deshpande LS, Lou JK, Mian A, Blair RE, Sombati S, DeLorenzo RJ. In vitro status epilepticus but not spontaneous recurrent seizures cause cell death in cultured hippocampal neurons. Epilepsy Research. 75: 171-9. PMID 17624736 DOI: 10.1016/j.eplepsyres.2007.05.011  1
2007 Deshpande LS, Limbrick DD, Sombati S, DeLorenzo RJ. Activation of a novel injury-induced calcium-permeable channel that plays a key role in causing extended neuronal depolarization and initiating neuronal death in excitotoxic neuronal injury. The Journal of Pharmacology and Experimental Therapeutics. 322: 443-52. PMID 17483292 DOI: 10.1124/jpet.107.123182  1
2007 DeLorenzo RJ, Sun DA, Blair RE, Sombati S. An in vitro model of stroke-induced epilepsy: elucidation of the roles of glutamate and calcium in the induction and maintenance of stroke-induced epileptogenesis. International Review of Neurobiology. 81: 59-84. PMID 17433918 DOI: 10.1016/S0074-7742(06)81005-6  1
2007 Falenski KW, Blair RE, Sim-Selley LJ, Martin BR, DeLorenzo RJ. Status epilepticus causes a long-lasting redistribution of hippocampal cannabinoid type 1 receptor expression and function in the rat pilocarpine model of acquired epilepsy. Neuroscience. 146: 1232-44. PMID 17433556 DOI: 10.1016/j.neuroscience.2007.01.065  1
2007 Raza M, Deshpande LS, Blair RE, Carter DS, Sombati S, DeLorenzo RJ. Aging is associated with elevated intracellular calcium levels and altered calcium homeostatic mechanisms in hippocampal neurons. Neuroscience Letters. 418: 77-81. PMID 17374449 DOI: 10.1016/j.neulet.2007.03.005  1
2007 Deshpande LS, Blair RE, Nagarkatti N, Sombati S, Martin BR, DeLorenzo RJ. Development of pharmacoresistance to benzodiazepines but not cannabinoids in the hippocampal neuronal culture model of status epilepticus. Experimental Neurology. 204: 705-13. PMID 17289026 DOI: 10.1016/j.expneurol.2007.01.001  1
2007 Deshpande LS, Blair RE, Ziobro JM, Sombati S, Martin BR, DeLorenzo RJ. Endocannabinoids block status epilepticus in cultured hippocampal neurons. European Journal of Pharmacology. 558: 52-9. PMID 17174949 DOI: 10.1016/j.ejphar.2006.11.030  1
2007 Deshpande LS, Sombati S, Blair RE, Carter DS, Martin BR, DeLorenzo RJ. Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy. Neuroscience Letters. 411: 11-6. PMID 17110038 DOI: 10.1016/j.neulet.2006.09.046  1
2006 Carter DS, Haider SN, Blair RE, Deshpande LS, Sombati S, DeLorenzo RJ. Altered calcium/calmodulin kinase II activity changes calcium homeostasis that underlies epileptiform activity in hippocampal neurons in culture. The Journal of Pharmacology and Experimental Therapeutics. 319: 1021-31. PMID 16971505 DOI: 10.1124/jpet.106.110403  1
2006 DeLorenzo RJ, Sun DA, Deshpande LS. Erratum to "Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintenance of epilepsy." [Pharmacol. Ther. 105(3) (2005) 229-266]. Pharmacology & Therapeutics. 111: 288-325. PMID 16832874  1
2006 Blair RE, Deshpande LS, Sombati S, Falenski KW, Martin BR, DeLorenzo RJ. Activation of the cannabinoid type-1 receptor mediates the anticonvulsant properties of cannabinoids in the hippocampal neuronal culture models of acquired epilepsy and status epilepticus. The Journal of Pharmacology and Experimental Therapeutics. 317: 1072-8. PMID 16469864 DOI: 10.1124/jpet.105.100354  1
2006 Leppik IE, Kelly KM, deToledo-Morrell L, Patrylo PR, DeLorenzo RJ, Mathern GW, White HS. Basic research in epilepsy and aging. Epilepsy Research. 68: S21-37. PMID 16384687 DOI: 10.1016/j.eplepsyres.2005.07.014  1
2006 DeLorenzo RJ. Epidemiology and clinical presentation of status epilepticus. Advances in Neurology. 97: 199-215. PMID 16383129  1
2006 DeLorenzo RJ, Sun DA. Basic mechanisms in status epilepticus: role of calcium in neuronal injury and the induction of epileptogenesis. Advances in Neurology. 97: 187-97. PMID 16383128  1
2005 Walker M, Cross H, Smith S, Young C, Aicardi J, Appleton R, Aylett S, Besag F, Cock H, DeLorenzo R, Drislane F, Duncan J, Ferrie C, Fujikawa D, Gray W, et al. Nonconvulsive status epilepticus: Epilepsy Research Foundation workshop reports. Epileptic Disorders : International Epilepsy Journal With Videotape. 7: 253-96. PMID 16162436  1
2005 Delorenzo RJ, Sun DA, Deshpande LS. Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintainance of epilepsy. Pharmacology & Therapeutics. 105: 229-66. PMID 15737406 DOI: 10.1016/j.pharmthera.2004.10.004  1
2005 Penberthy LT, Towne A, Garnett LK, Perlin JB, DeLorenzo RJ. Estimating the economic burden of status epilepticus to the health care system. Seizure. 14: 46-51. PMID 15642500 DOI: 10.1016/j.seizure.2004.06.001  1
2004 Raza M, Blair RE, Sombati S, Carter DS, Deshpande LS, DeLorenzo RJ. Evidence that injury-induced changes in hippocampal neuronal calcium dynamics during epileptogenesis cause acquired epilepsy. Proceedings of the National Academy of Sciences of the United States of America. 101: 17522-7. PMID 15583136 DOI: 10.1073/pnas.0408155101  1
2004 Parsons JT, Sun DA, DeLorenzo RJ, Churn SB. Neuronal-specific endoplasmic reticulum Mg(2+)/Ca(2+) ATPase Ca(2+) sequestration in mixed primary hippocampal culture homogenates. Analytical Biochemistry. 330: 130-9. PMID 15183771 DOI: 10.1016/j.ab.2004.03.025  1
2004 Pellock JM, Marmarou A, DeLorenzo R. Time to treatment in prolonged seizure episodes Epilepsy and Behavior. 5: 192-196. PMID 15123020 DOI: 10.1016/j.yebeh.2003.12.012  1
2004 Blair RE, Sombati S, Lawrence DC, McCay BD, DeLorenzo RJ. Epileptogenesis causes acute and chronic increases in GABAA receptor endocytosis that contributes to the induction and maintenance of seizures in the hippocampal culture model of acquired epilepsy. The Journal of Pharmacology and Experimental Therapeutics. 310: 871-80. PMID 15084648 DOI: 10.1124/jpet.104.068478  1
2004 Raza M, Shaheen F, Choudhary MI, Sombati S, Rahman AU, DeLorenzo RJ. Inhibition of sustained repetitive firing in cultured hippocampal neurons by an aqueous fraction isolated from Delphinium denudatum. Journal of Ethnopharmacology. 90: 367-74. PMID 15013203 DOI: 10.1016/j.jep.2003.10.017  1
2004 Corey LA, Pellock JM, DeLorenzo RJ. Status epilepticus in a population-based Virginia twin sample. Epilepsia. 45: 159-65. PMID 14738423 DOI: 10.1111/j.0013-9580.2004.34303.x  1
2004 Sun DA, Sombati S, Blair RE, DeLorenzo RJ. Long-lasting alterations in neuronal calcium homeostasis in an in vitro model of stroke-induced epilepsy. Cell Calcium. 35: 155-63. PMID 14706289 DOI: 10.1016/j.ceca.2003.09.003  1
2003 Wallace MJ, Blair RE, Falenski KW, Martin BR, DeLorenzo RJ. The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy. The Journal of Pharmacology and Experimental Therapeutics. 307: 129-37. PMID 12954810 DOI: 10.1124/jpet.103.051920  1
2003 Rafiq A, Gong QZ, Lyeth BG, DeLorenzo RJ, Coulter DA. Induction of prolonged electrographic seizures in vitro has a defined threshold and is all or none: implications for diagnosis of status epilepticus. Epilepsia. 44: 1034-41. PMID 12887434 DOI: 10.1046/j.1528-1157.2003.51902.x  1
2003 Raza M, Shaheen F, Choudhary MI, Rahman AU, Sombati S, Suria A, Rafiq A, DeLorenzo RJ. Anticonvulsant effect of FS-1 subfraction isolated from roots of Delphinim denudatum on hippocampal pyramidal neurons. Phytotherapy Research : Ptr. 17: 38-43. PMID 12557245 DOI: 10.1002/ptr.1072  1
2003 Towne AR, Garnett LK, Waterhouse EJ, Morton LD, DeLorenzo RJ. The use of topiramate in refractory status epilepticus. Neurology. 60: 332-4. PMID 12552056  1
2003 Limbrick DD, Sombati S, DeLorenzo RJ. Calcium influx constitutes the ionic basis for the maintenance of glutamate-induced extended neuronal depolarization associated with hippocampal neuronal death. Cell Calcium. 33: 69-81. PMID 12531183 DOI: 10.1016/S0143-4160(02)00054-4  1
2002 Sun DA, Sombati S, Blair RE, DeLorenzo RJ. Calcium-dependent epileptogenesis in an in vitro model of stroke-induced "epilepsy". Epilepsia. 43: 1296-305. PMID 12423378 DOI: 10.1046/j.1528-1157.2002.09702.x  1
2002 Raza M, Shaheen F, Choudhary MI, Rahman AU, Sombati S, DeLorenzo RJ. In vitro inhibition of pentylenetetrazole and bicuculline-induced epileptiform activity in rat hippocampal pyramidal neurons by aqueous fraction isolated from Delphinium denudatum. Neuroscience Letters. 333: 103-6. PMID 12419491 DOI: 10.1016/S0304-3940(02)01027-3  1
2002 Wallace MJ, Martin BR, DeLorenzo RJ. Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity. European Journal of Pharmacology. 452: 295-301. PMID 12359270 DOI: 10.1016/S0014-2999(02)02331-2  1
2002 Churn SB, Rana A, Lee K, Parsons JT, De Blas A, Delorenzo RJ. Calcium/calmodulin-dependent kinase II phosphorylation of the GABAA receptor alpha1 subunit modulates benzodiazepine binding. Journal of Neurochemistry. 82: 1065-76. PMID 12358754 DOI: 10.1046/j.1471-4159.2002.01032.x  1
2001 Wallace MJ, Wiley JL, Martin BR, DeLorenzo RJ. Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects. European Journal of Pharmacology. 428: 51-7. PMID 11779037 DOI: 10.1016/S0014-2999(01)01243-2  1
2001 Parsons JT, Churn SB, DeLorenzo RJ. Chronic inhibition of cortex microsomal Mg(2+)/Ca(2+) ATPase-mediated Ca(2+) uptake in the rat pilocarpine model following epileptogenesis. Journal of Neurochemistry. 79: 319-27. PMID 11677260 DOI: 10.1046/j.1471-4159.2001.00576.x  1
2001 Sun DA, Sombati S, DeLorenzo RJ. Glutamate injury-induced epileptogenesis in hippocampal neurons: an in vitro model of stroke-induced "epilepsy". Stroke; a Journal of Cerebral Circulation. 32: 2344-50. PMID 11588324  1
2001 Pal S, Sun D, Limbrick D, Rafiq A, DeLorenzo RJ. Epileptogenesis induces long-term alterations in intracellular calcium release and sequestration mechanisms in the hippocampal neuronal culture model of epilepsy. Cell Calcium. 30: 285-96. PMID 11587552 DOI: 10.1054/ceca.2001.0236  1
2001 Raza M, Shaheen F, Choudhary MI, Sombati S, Rafiq A, Suria A, Rahman A, DeLorenzo RJ. Anticonvulsant activities of ethanolic extract and aqueous fraction isolated from Delphinium denudatum. Journal of Ethnopharmacology. 78: 73-8. PMID 11585691 DOI: 10.1016/S0378-8741(01)00327-0  1
2001 Raza M, Shaheen F, Choudhary MI, Suria A, Rahman AU, Sombati S, DeLorenzo RJ. Anticonvulsant activities of the FS-1 subfraction isolated from roots of Delphinium denudatum. Phytotherapy Research : Ptr. 15: 426-30. PMID 11507736 DOI: 10.1002/ptr.792  1
2001 Kurz JE, Sheets D, Parsons JT, Rana A, Delorenzo RJ, Churn SB. A significant increase in both basal and maximal calcineurin activity in the rat pilocarpine model of status epilepticus. Journal of Neurochemistry. 78: 304-15. PMID 11461966 DOI: 10.1046/j.1471-4159.2001.00426.x  1
2001 Raza M, Pal S, Rafiq A, DeLorenzo RJ. Long-term alteration of calcium homeostatic mechanisms in the pilocarpine model of temporal lobe epilepsy. Brain Research. 903: 1-12. PMID 11382382 DOI: 10.1016/S0006-8993(01)02127-8  1
2001 Waterhouse EJ, DeLorenzo RJ. Status epilepticus in older patients: epidemiology and treatment options. Drugs & Aging. 18: 133-42. PMID 11346127  1
2001 Limbrick DD, Pal S, DeLorenzo RJ. Hippocampal neurons exhibit both persistent Ca2+ influx and impairment of Ca2+ sequestration/extrusion mechanisms following excitotoxic glutamate exposure. Brain Research. 894: 56-67. PMID 11245815 DOI: 10.1016/S0006-8993(00)03303-5  1
2001 Shinnar S, Pellock JM, Berg AT, O'Dell C, Driscoll SM, Maytal J, Moshe SL, DeLorenzo RJ. Short-term outcomes of children with febrile status epilepticus. Epilepsia. 42: 47-53. PMID 11207784 DOI: 10.1046/j.1528-1157.2001.10000.x  1
2001 DeLorenzo RJ. A specialized treatment program for recurrent, severe, unilateral headaches that do not decrease in frequency or intensity with conventional treatment: DeLorenzo's syndrome Headache Quarterly. 12: 173-179.  1
2000 Pal S, Limbrick DD, Rafiq A, DeLorenzo RJ. Induction of spontaneous recurrent epileptiform discharges causes long-term changes in intracellular calcium homeostatic mechanisms. Cell Calcium. 28: 181-93. PMID 11020380 DOI: 10.1054/ceca.2000.0146  1
2000 Churn SB, Kochan LD, DeLorenzo RJ. Chronic inhibition of Ca(2+)/calmodulin kinase II activity in the pilocarpine model of epilepsy. Brain Research. 875: 66-77. PMID 10967300 DOI: 10.1016/S0006-8993(00)02623-8  1
2000 Parsons JT, Churn SB, Kochan LD, DeLorenzo RJ. Pilocarpine-induced status epilepticus causes N-methyl-D-aspartate receptor-dependent inhibition of microsomal Mg(2+)/Ca(2+) ATPase-mediated Ca(2+) uptake. Journal of Neurochemistry. 75: 1209-18. PMID 10936204 DOI: 10.1046/j.1471-4159.2000.0751209.x  1
2000 Morris TA, Jafari N, DeLorenzo RJ. Chronic DeltaFosB expression and increased AP-1 transcription factor binding are associated with the long term plasticity changes in epilepsy. Brain Research. Molecular Brain Research. 79: 138-49. PMID 10925151 DOI: 10.1016/S0169-328X(00)00112-1  1
2000 Churn SB, Sombati S, Jakoi ER, Severt L, DeLorenzo RJ, Sievert L. Inhibition of calcium/calmodulin kinase II alpha subunit expression results in epileptiform activity in cultured hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 97: 5604-9. PMID 10779547 DOI: 10.1073/pnas.080071697  1
2000 DeLorenzo RJ, Sombati S, Coulter DA. Effects of topiramate on sustained repetitive firing and spontaneous recurrent seizure discharges in cultured hippocampal neurons. Epilepsia. 41: S40-4. PMID 10768299  1
2000 Gibbs JW, Sombati S, DeLorenzo RJ, Coulter DA. Cellular actions of topiramate: blockade of kainate-evoked inward currents in cultured hippocampal neurons. Epilepsia. 41: S10-6. PMID 10768293  1
2000 Kochan LD, Churn SB, Omojokun O, Rice A, DeLorenzo RJ. Status epilepticus results in an N-methyl-D-aspartate receptor-dependent inhibition of Ca2+/calmodulin-dependent kinase II activity in the rat. Neuroscience. 95: 735-43. PMID 10670440 DOI: 10.1016/S0306-4522(99)00462-5  1
2000 Towne AR, Waterhouse EJ, Boggs JG, Garnett LK, Brown AJ, Smith JR, DeLorenzo RJ. Prevalence of nonconvulsive status epilepticus in comatose patients. Neurology. 54: 340-5. PMID 10668693  1
1999 Blair RE, Churn SB, Sombati S, Lou JK, DeLorenzo RJ. Long-lasting decrease in neuronal Ca2+/calmodulin-dependent protein kinase II activity in a hippocampal neuronal culture model of spontaneous recurrent seizures. Brain Research. 851: 54-65. PMID 10642828 DOI: 10.1016/S0006-8993(99)02100-9  1
1999 Pal S, Sombati S, Limbrick DD, DeLorenzo RJ. In vitro status epilepticus causes sustained elevation of intracellular calcium levels in hippocampal neurons. Brain Research. 851: 20-31. PMID 10642824 DOI: 10.1016/S0006-8993(99)02035-1  1
1999 Severt WL, Biber TU, Wu X, Hecht NB, DeLorenzo RJ, Jakoi ER. The suppression of testis-brain RNA binding protein and kinesin heavy chain disrupts mRNA sorting in dendrites. Journal of Cell Science. 112: 3691-702. PMID 10523505  1
1999 Coulter DA, DeLorenzo RJ. Basic mechanisms of status epilepticus. Advances in Neurology. 79: 725-33. PMID 10514858  1
1999 Morris TA, Jafari N, Rice AC, Vasconcelos O, DeLorenzo RJ. Persistent increased DNA-binding and expression of serum response factor occur with epilepsy-associated long-term plasticity changes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8234-43. PMID 10493724  1
1999 Rice AC, DeLorenzo RJ. N-methyl-D-aspartate receptor activation regulates refractoriness of status epilepticus to diazepam. Neuroscience. 93: 117-23. PMID 10430476 DOI: 10.1016/S0306-4522(99)00132-3  1
1999 Parsons JT, Churn SB, DeLorenzo RJ. Global ischemia-induced inhibition of the coupling ratio of calcium uptake and ATP hydrolysis by rat whole brain microsomal Mg(2+)/Ca(2+) ATPase. Brain Research. 834: 32-41. PMID 10407091 DOI: 10.1016/S0006-8993(99)01504-8  1
1999 Waterhouse EJ, Garnett LK, Towne AR, Morton LD, Barnes T, Ko D, DeLorenzo RJ. Prospective population-based study of intermittent and continuous convulsive status epilepticus in Richmond, Virginia. Epilepsia. 40: 752-8. PMID 10368074 DOI: 10.1111/j.1528-1157.1999.tb00774.x  1
1999 Miller LL, Pellock JM, Boggs JG, DeLorenzo RJ, Meyer JM, Corey LA. Epilepsy and seizure occurrence in a population-based sample of Virginian twins and their families. Epilepsy Research. 34: 135-43. PMID 10210028 DOI: 10.1016/S0920-1211(98)00113-2  1
1999 Towne AR, DeLorenzo RJ. Use of intramuscular midazolam for status epilepticus. The Journal of Emergency Medicine. 17: 323-8. PMID 10195494 DOI: 10.1016/S0736-4679(98)00170-X  1
1999 DeLorenzo RJ, Garnett LK, Towne AR, Waterhouse EJ, Boggs JG, Morton L, Choudhry MA, Barnes T, Ko D. Comparison of status epilepticus with prolonged seizure episodes lasting from 10 to 29 minutes. Epilepsia. 40: 164-9. PMID 9952262 DOI: 10.1111/j.1528-1157.1999.tb02070.x  1
1999 Delorenzo RJ, Morris TA. Long-term modulation of gone expression in epilepsy Neuroscientist. 5: 86-99.  1
1998 DeLorenzo RJ, Pal S, Sombati S. Prolonged activation of the N-methyl-D-aspartate receptor-Ca2+ transduction pathway causes spontaneous recurrent epileptiform discharges in hippocampal neurons in culture. Proceedings of the National Academy of Sciences of the United States of America. 95: 14482-7. PMID 9826726 DOI: 10.1073/pnas.95.24.14482  1
1998 Rice AC, Floyd CL, Lyeth BG, Hamm RJ, DeLorenzo RJ. Status epilepticus causes long-term NMDA receptor-dependent behavioral changes and cognitive deficits. Epilepsia. 39: 1148-57. PMID 9821978  1
1998 Churn SB, DeLorenzo RJ. Modulation of GABAergic receptor binding by activation of calcium and calmodulin-dependent kinase II membrane phosphorylation. Brain Research. 809: 68-76. PMID 9795142 DOI: 10.1016/S0006-8993(98)00834-8  1
1998 Parsons JT, Churn SB, DeLorenzo RJ. Separation of radiolabeled orthophosphate and adenosine 5'-triphosphate by 20% polyacrylamide gel electrophoresis: an assay for brain microsomal Mg2+/Ca2+ ATPase activity. Analytical Biochemistry. 264: 74-81. PMID 9784190 DOI: 10.1006/abio.1998.2822  1
1998 Boggs JG, Marmarou A, Agnew JP, Morton LD, Towne AR, Waterhouse EJ, Pellock JM, DeLorenzo RJ. Hemodynamic monitoring prior to and at the time of death in status epilepticus. Epilepsy Research. 31: 199-209. PMID 9722030 DOI: 10.1016/S0920-1211(98)00031-X  1
1998 DeLorenzo RJ, Waterhouse EJ, Towne AR, Boggs JG, Ko D, DeLorenzo GA, Brown A, Garnett L. Persistent nonconvulsive status epilepticus after the control of convulsive status epilepticus. Epilepsia. 39: 833-40. PMID 9701373  1
1998 Morris TA, DeLorenzo RJ, Tombes RM. CaMK-II inhibition reduces cyclin D1 levels and enhances the association of p27kip1 with Cdk2 to cause G1 arrest in NIH 3T3 cells. Experimental Cell Research. 240: 218-27. PMID 9596994 DOI: 10.1006/excr.1997.3925  1
1998 Waterhouse EJ, Vaughan JK, Barnes TY, Boggs JG, Towne AR, Kopec-Garnett L, DeLorenzo RJ. Synergistic effect of status epilepticus and ischemic brain injury on mortality. Epilepsy Research. 29: 175-83. PMID 9551779 DOI: 10.1016/S0920-1211(97)00071-5  1
1998 Miller LL, Pellock JM, DeLorenzo RJ, Meyer JM, Corey LA. Univariate genetic analyses of epilepsy and seizures in a population-based twin study: the Virginia Twin Registry. Genetic Epidemiology. 15: 33-49. PMID 9523209 DOI: 10.1002/(SICI)1098-2272(1998)15:1<33::AID-GEPI3>3.0.CO;2-5  1
1998 Rice AC, DeLorenzo RJ. NMDA receptor activation during status epilepticus is required for the development of epilepsy. Brain Research. 782: 240-7. PMID 9519269 DOI: 10.1016/S0006-8993(97)01285-7  1
1998 Corey LA, Pellock JM, Boggs JG, Miller LL, DeLorenzo RJ. Evidence for a genetic predisposition for status epilepticus. Neurology. 50: 558-60. PMID 9484400  1
1997 Shinnar S, Pellock JM, Moshé SL, Maytal J, O'Dell C, Driscoll SM, Alemany M, Newstein D, DeLorenzo RJ. In whom does status epilepticus occur: age-related differences in children. Epilepsia. 38: 907-14. PMID 9579892 DOI: 10.1111/j.1528-1157.1997.tb01256.x  1
1997 Jaitly R, Sgro JA, Towne AR, Ko D, DeLorenzo RJ. Prognostic value of EEG monitoring after status epilepticus: a prospective adult study. Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society. 14: 326-34. PMID 9337142 DOI: 10.1097/00004691-199707000-00005  1
1997 Gibbs JW, Sombati S, DeLorenzo RJ, Coulter DA. Physiological and pharmacological alterations in postsynaptic GABA(A) receptor function in a hippocampal culture model of chronic spontaneous seizures. Journal of Neurophysiology. 77: 2139-52. PMID 9114261  1
1997 Parsons JT, Churn SB, DeLorenzo RJ. Ischemia-induced inhibition of calcium uptake into rat brain microsomes mediated by Mg2+/Ca2+ ATPase. Journal of Neurochemistry. 68: 1124-34. PMID 9048758  1
1996 Coulter DA, Rafiq A, Shumate M, Gong QZ, DeLorenzo RJ, Lyeth BG. Brain injury-induced enhanced limbic epileptogenesis: anatomical and physiological parallels to an animal model of temporal lobe epilepsy. Epilepsy Research. 26: 81-91. PMID 8985690 DOI: 10.1016/S0920-1211(96)00044-7  1
1996 DeLorenzo RJ. Management of status epilepticus. Virginia Medical Quarterly : Vmq. 123: 103-11. PMID 8810891  1
1996 Vick RS, Rafiq A, Coulter DA, Jakoi ER, DeLorenzo RJ. GABAA alpha 2 mRNA levels are decreased following induction of spontaneous epileptiform discharges in hippocampal-entorhinal cortical slices. Brain Research. 721: 111-9. PMID 8793090 DOI: 10.1016/0006-8993(96)00060-1  1
1996 DeLorenzo RJ, Limbrick DD. Effects of glutamate on calcium influx and sequestration/extrusion mechanisms in hippocampal neurons. Advances in Neurology. 71: 37-46. PMID 8790787  1
1996 Rice A, Rafiq A, Shapiro SM, Jakoi ER, Coulter DA, DeLorenzo RJ. Long-lasting reduction of inhibitory function and gamma-aminobutyric acid type A receptor subunit mRNA expression in a model of temporal lobe epilepsy. Proceedings of the National Academy of Sciences of the United States of America. 93: 9665-9. PMID 8790388 DOI: 10.1073/pnas.93.18.9665  1
1996 DeLorenzo RJ, Hauser WA, Towne AR, Boggs JG, Pellock JM, Penberthy L, Garnett L, Fortner CA, Ko D. A prospective, population-based epidemiologic study of status epilepticus in Richmond, Virginia. Neurology. 46: 1029-35. PMID 8780085  1
1995 Jakoi ER, Panchision DM, Gerwin CM, DeLorenzo RJ. Post-transcriptional regulation of gene expression in hippocampal neurons by glutamate receptor activation. Brain Research. 693: 124-32. PMID 8653400 DOI: 10.1016/0006-8993(95)00599-L  1
1995 Churn SB, DeLorenzo RJ, Shapiro SM. Bilirubin induces a calcium-dependent inhibition of multifunctional Ca2+/calmodulin-dependent kinase II activity in vitro. Pediatric Research. 38: 949-54. PMID 8618799 DOI: 10.1203/00006450-199512000-00020  1
1995 Rafiq A, Zhang YF, DeLorenzo RJ, Coulter DA. Long-duration self-sustained epileptiform activity in the hippocampal-parahippocampal slice: a model of status epilepticus. Journal of Neurophysiology. 74: 2028-42. PMID 8592194  1
1995 Limbrick DD, Churn SB, Sombati S, DeLorenzo RJ. Inability to restore resting intracellular calcium levels as an early indicator of delayed neuronal cell death. Brain Research. 690: 145-56. PMID 8535831 DOI: 10.1016/0006-8993(95)00552-2  1
1995 Churn SB, Limbrick D, Sombati S, DeLorenzo RJ. Excitotoxic activation of the NMDA receptor results in inhibition of calcium/calmodulin kinase II activity in cultured hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 3200-14. PMID 7722657  1
1995 Sombati S, Delorenzo RJ. Recurrent spontaneous seizure activity in hippocampal neuronal networks in culture. Journal of Neurophysiology. 73: 1706-11. PMID 7643176  1
1995 Panchision DM, Gerwin CM, DeLorenzo RJ, Jakoi ER. Glutamate receptor activation regulates mRNA at both transcriptional and posttranscriptional levels. Journal of Neurochemistry. 65: 969-77. PMID 7643127  1
1995 DeLorenzo RJ, Pellock JM, Towne AR, Boggs JG. Epidemiology of status epilepticus. Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society. 12: 316-25. PMID 7560020  1
1995 Dodson WE, DeLorenzo RJ, Pedley TA, Shinnar S, Treimann DM, Wannamaker BB. Treatment of convulsive status epilepticus | BEHANDLUNG DES KONVULSIVEN STATUS EPILEPTICUS Sozialpadiatrie Und Kinderarztliche Praxis. 17: 87-89.  1
1994 Towne AR, Pellock JM, Ko D, DeLorenzo RJ. Determinants of mortality in status epilepticus. Epilepsia. 35: 27-34. PMID 8112254  1
1994 Kapur J, Lothman EW, DeLorenzo RJ. Loss of GABAA receptors during partial status epilepticus. Neurology. 44: 2407-8. PMID 7991140  1
1994 Delorenzo RJ. Editorial comment Stroke. 25: 480.  1
1993 Boggs JG, Painter JA, DeLorenzo RJ. Analysis of electrocardiographic changes in status epilepticus. Epilepsy Research. 14: 87-94. PMID 8449182 DOI: 10.1016/0920-1211(93)90077-K  1
1993 Perlin JB, Gerwin CM, Panchision DM, Vick RS, Jakoi ER, DeLorenzo RJ. Kindling produces long-lasting and selective changes in gene expression of hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 90: 1741-5. PMID 8446587  1
1993 Churn SB, Sankaran B, Haley BE, DeLorenzo RJ. Ischemic brain injury selectively alters ATP binding of calcium and calmodulin-dependent protein kinase II. Biochemical and Biophysical Research Communications. 193: 934-40. PMID 8391812 DOI: 10.1006/bbrc.1993.1715  1
1993 Sgro JA, Jaitly R, DeLorenzo RJ. Conventional and rapid stimulation evoked potential changes in patients with status epilepticus. Epilepsy Research. 15: 149-56. PMID 8370352 DOI: 10.1016/0920-1211(93)90095-O  1
1993 Calabrese VP, Gruemer HD, Tripathi HL, Dewey W, Fortner CA, DeLorenzo RJ. Serum cortisol and cerebrospinal fluid beta-endorphins in status epilepticus. Their possible relation to prognosis. Archives of Neurology. 50: 689-93. PMID 8323469 DOI: 10.1001/archneur.1993.00540070009006  1
1993 Rafiq A, DeLorenzo RJ, Coulter DA. Generation and propagation of epileptiform discharges in a combined entorhinal cortex/hippocampal slice. Journal of Neurophysiology. 70: 1962-74. PMID 8294965  1
1993 Churn SB, Sombati S, Taft WC, DeLorenzo RJ. Excitotoxicity affects membrane potential and calmodulin kinase II activity in cultured rat cortical neurons. Stroke; a Journal of Cerebral Circulation. 24: 271-7; discussion 27. PMID 8093648  1
1993 DeLorenzo RJ. Correction Stroke. 24: 616.  1
1992 DeLorenzo RJ, Towne AR, Pellock JM, Ko D. Status epilepticus in children, adults, and the elderly. Epilepsia. 33: S15-25. PMID 1425490  1
1992 Coulter DA, Sombati S, DeLorenzo RJ. Electrophysiology of glutamate neurotoxicity in vitro: induction of a calcium-dependent extended neuronal depolarization. Journal of Neurophysiology. 68: 362-73. PMID 1388200  1
1992 Jakoi ER, Sombati S, Gerwin C, DeLorenzo RJ. Excitatory amino acid receptor activation produces a selective and long-lasting modulation of gene expression in hippocampal neurons. Brain Research. 582: 282-90. PMID 1382803 DOI: 10.1016/0006-8993(92)90145-Y  1
1992 Churn SB, Taft WC, Billingsley MS, Sankaran B, DeLorenzo RJ. Global forebrain ischemia induces a posttranslational modification of multifunctional calcium- and calmodulin-dependent kinase II. Journal of Neurochemistry. 59: 1221-32. PMID 1328515  1
1992 Churn SB, Yaghmai A, Povlishock J, Rafiq A, DeLorenzo RJ. Global forebrain ischemia results in decreased immunoreactivity of calcium/calmodulin-dependent protein kinase II. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 12: 784-93. PMID 1324253 DOI: 10.1038/jcbfm.1992.109  1
1992 Perlin JB, Churn SB, Lothman EW, DeLorenzo RJ. Loss of type II calcium/calmodulin-dependent kinase activity correlates with stages of development of electrographic seizures in status epilepticus in rat. Epilepsy Research. 11: 111-8. PMID 1319899 DOI: 10.1016/0920-1211(92)90045-U  1
1991 DeLorenzo RJ. The challenging genetics of epilepsy. Epilepsy Research. Supplement. 4: 3-17. PMID 1815608  1
1991 Calabrese VP, Gruemer HD, James K, Hranowsky N, DeLorenzo RJ. Cerebrospinal fluid lactate levels and prognosis in status epilepticus. Epilepsia. 32: 816-21. PMID 1743153  1
1991 Sombati S, Coulter DA, DeLorenzo RJ. Neurotoxic activation of glutamate receptors induces an extended neuronal depolarization in cultured hippocampal neurons. Brain Research. 566: 316-9. PMID 1687663 DOI: 10.1016/0006-8993(91)91716-E  1
1991 Churn SB, Anderson WW, DeLorenzo RJ. Exposure of hippocampal slices to magnesium-free medium produces epileptiform activity and simultaneously decreases calcium and calmodulin-dependent protein kinase II activity. Epilepsy Research. 9: 211-7. PMID 1660400 DOI: 10.1016/0920-1211(91)90054-J  1
1990 DeLorenzo RJ. Status epilepticus: concepts in diagnosis and treatment. Seminars in Neurology. 10: 396-405. PMID 2287834 DOI: 10.1055/s-2008-1063984  1
1990 Churn SB, Taft WC, Billingsley MS, Blair RE, DeLorenzo RJ. Temperature modulation of ischemic neuronal death and inhibition of calcium/calmodulin-dependent protein kinase II in gerbils. Stroke; a Journal of Cerebral Circulation. 21: 1715-21. PMID 2264078  1
1990 Churn SB, Taft WC, DeLorenzo RJ. Effects of ischemia on multifunctional calcium/calmodulin-dependent protein kinase type II in the gerbil. Stroke; a Journal of Cerebral Circulation. 21: III112-6. PMID 2173173  1
1989 Clifton GL, Taft WC, Blair RE, Choi SC, DeLorenzo RJ. Conditions for pharmacologic evaluation in the gerbil model of forebrain ischemia. Stroke; a Journal of Cerebral Circulation. 20: 1545-52. PMID 2815190  1
1989 Clifton GL, Lyeth BG, Jenkins LW, Taft WC, DeLorenzo RJ, Hayes RL. Effect of D, alpha-tocopheryl succinate and polyethylene glycol on performance tests after fluid percussion brain injury. Journal of Neurotrauma. 6: 71-81. PMID 2769771  1
1989 Taft WC, Clifton GL, Blair RE, DeLorenzo RJ. Phenytoin protects against ischemia-produced neuronal cell death. Brain Research. 483: 143-8. PMID 2706503 DOI: 10.1016/0006-8993(89)90045-0  1
1989 Delorenzo RJ, Sgro JA. Basic mechanisms of neuronal excitability and anticonvulsant action Art and Science of Epilepsy: Proceedings of the 2nd International Symposium of the Psychiatric Research Institute of Tokyo. Ics825. 39-45.  1
1988 DeLorenzo RJ. Mechanisms of action of anticonvulsant drugs. Epilepsia. 29: S35-47. PMID 2844522  1
1988 Taft WC, Tennes-Rees KA, Blair RE, Clifton GL, DeLorenzo RJ. Cerebral ischemia decreases endogenous calcium-dependent protein phosphorylation in gerbil brain. Brain Research. 447: 159-63. PMID 2838127 DOI: 10.1016/0006-8993(88)90978-X  1
1987 Ishiguro K, Taft WC, DeLorenzo RJ, Sartorelli AC. The role of benzodiazepine receptors in the induction of differentiation of HL-60 leukemia cells by benzodiazepines and purines. Journal of Cellular Physiology. 131: 226-34. PMID 3034922 DOI: 10.1002/jcp.1041310212  1
1987 Bowling AC, DeLorenzo RJ. Photoaffinity labeling of a novel benzodiazepine binding protein in rat brain. European Journal of Pharmacology. 135: 97-100. PMID 3032662 DOI: 10.1016/0014-2999(87)90763-1  1
1987 Taft WC, Goldenring JR, DeLorenzo RJ. Molecular mechanisms of neuronal excitability: possible involvement of CaM kinase II in seizure activity. Advances in Experimental Medicine and Biology. 221: 409-25. PMID 2829586  1
1987 Harris JK, DeLorenzo RJ. Calcium and neuronal cytoskeletal proteins: alterations with aging. Neurobiology of Aging. 8: 359-61. PMID 2819753 DOI: 10.1016/0197-4580(87)90080-7  1
1987 Yang J, Johansen J, Kleinhaus AL, DeLorenzo RJ, Zorumski CF. Effects of medazepam on voltage-gated ion currents of cultured chick sensory neurons. European Journal of Pharmacology. 143: 373-81. PMID 2446893 DOI: 10.1016/0014-2999(87)90461-4  1
1987 Taft WC, DeLorenzo RJ. Regulation of calcium channels in brain: implications for the clinical neurosciences. The Yale Journal of Biology and Medicine. 60: 99-106. PMID 2437710  1
1987 Kreutter D, Kim JY, Goldenring JR, Rasmussen H, Ukomadu C, DeLorenzo RJ, Yu RK. Regulation of protein kinase C activity by gangliosides. The Journal of Biological Chemistry. 262: 1633-7. PMID 2433284  1
1986 Goldenring JR, Wasterlain CG, Oestreicher AB, de Graan PN, Farber DB, Glaser G, DeLorenzo RJ. Kindling induces a long-lasting change in the activity of a hippocampal membrane calmodulin-dependent protein kinase system. Brain Research. 377: 47-53. PMID 3730855 DOI: 10.1016/0006-8993(86)91189-3  1
1986 Vallano ML, Goldenring JR, Lasher RS, Delorenzo RJ. Association of calcium/calmodulin-dependent kinase with cytoskeletal preparations: phosphorylation of tubulin, neurofilament, and microtubule-associated proteins. Annals of the New York Academy of Sciences. 466: 357-74. PMID 3089108  1
1986 Goldenring JR, Lasher RS, Vallano ML, Ueda T, Naito S, Sternberger NH, Sternberger LA, DeLorenzo RJ. Association of synapsin I with neuronal cytoskeleton. Identification in cytoskeletal preparations in vitro and immunocytochemical localization in brain of synapsin I. The Journal of Biological Chemistry. 261: 8495-504. PMID 3087974  1
1986 Goldenring JR, DeLorenzo RJ. Phosphorylation of MAP-2 at distinct sites by calmodulin- and cyclic AMP-dependent kinases. Annals of the New York Academy of Sciences. 466: 457-9. PMID 3014968  1
1986 Vallano ML, DeLorenzo RJ. Separation of microtubule-associated cAMP and calmodulin-dependent kinases that phosphorylate MAP-2. Annals of the New York Academy of Sciences. 466: 453-6. PMID 3014967  1
1986 DeLorenzo RJ. A molecular approach to the calcium signal in brain: relationship to synaptic modulation and seizure discharge. Advances in Neurology. 44: 435-64. PMID 3010680  1
1986 Chin JH, DeLorenzo RJ. A new class of adenosine receptors in brain. Characterization by 2-chloro[3H]adenosine binding. Biochemical Pharmacology. 35: 847-56. PMID 3006693 DOI: 10.1016/0006-2952(86)90254-6  1
1986 Goldenring JR, Vallano ML, Lasher RS, Ueda T, DeLorenzo RJ. Association of calmodulin-dependent kinase II and its substrate proteins with neuronal cytoskeleton. Progress in Brain Research. 69: 341-54. PMID 2833804  1
1986 DeLorenzo RJ, Bowling AC, Taft WC. A molecular approach to the development of anticonvulsants. Annals of the New York Academy of Sciences. 477: 238-46. PMID 2433983  1
1986 Kim JY, Goldenring JR, DeLorenzo RJ, Yu RK. Gangliosides inhibit phospholipid-sensitive Ca2+-dependent kinase phosphorylation of rat myelin basic proteins. Journal of Neuroscience Research. 15: 159-66. PMID 2421006 DOI: 10.1002/jnr.490150205  1
1985 Billingsley ML, Velletri PA, Lovenberg W, Kuhn D, Goldenring JR, DeLorenzo RJ. Is Ca2+-calmodulin-dependent protein phosphorylation in rat brain modulated by carboxylmethylation? Journal of Neurochemistry. 44: 1442-50. PMID 3989542 DOI: 10.1111/j.1471-4159.1985.tb08781.x  1
1985 Vallano ML, Goldenring JR, Buckholz TM, Larson RE, DeLorenzo RJ. Separation of endogenous calmodulin- and cAMP-dependent kinases from microtubule preparations. Proceedings of the National Academy of Sciences of the United States of America. 82: 3202-6. PMID 3858817 DOI: 10.1073/pnas.82.10.3202  1
1985 Chin JH, Buckholz TM, DeLorenzo RJ. Calmodulin and protein phosphorylation: implications in brain ischemia. Progress in Brain Research. 63: 169-84. PMID 3012634 DOI: 10.1016/S0079-6123(08)61982-2  1
1985 Chin JH, Delorenzo RJ. Cobalt ion enhancement of 2-chloro[3H]adenosine binding to a novel class of adenosine receptors in brain: antagonism by calcium. Brain Research. 348: 381-6. PMID 3000507 DOI: 10.1016/0006-8993(85)90462-7  1
1985 Goldenring JR, Vallano ML, DeLorenzo RJ. Phosphorylation of microtubule-associated protein 2 at distinct sites by calmodulin-dependent and cyclic-AMP-dependent kinases. Journal of Neurochemistry. 45: 900-5. PMID 2993517  1
1985 Vallano ML, Buckholz TM, DeLorenzo RJ. Phosphorylation of neurofilament proteins by endogenous calcium/calmodulin-dependent protein kinase. Biochemical and Biophysical Research Communications. 130: 957-63. PMID 2992511 DOI: 10.1016/0006-291X(85)91708-5  1
1985 Larson RE, Goldenring JR, Vallano ML, DeLorenzo RJ. Identification of endogenous calmodulin-dependent kinase and calmodulin-binding proteins in cold-stable microtubule preparations from rat brain. Journal of Neurochemistry. 44: 1566-74. PMID 2985755  1
1985 Chin JH, Mashman WE, DeLorenzo RJ. Novel adenosine receptors in rat hippocampus. Identification and characterization. Life Sciences. 36: 1751-60. PMID 2984508 DOI: 10.1016/0024-3205(85)90558-2  1
1985 Goldenring JR, Otis LC, Yu RK, DeLorenzo RJ. Calcium/ganglioside-dependent protein kinase activity in rat brain membrane. Journal of Neurochemistry. 44: 1229-34. PMID 2579206  1
1984 Goldenring JR, McGuire JS, DeLorenzo RJ. Identification of the major postsynaptic density protein as homologous with the major calmodulin-binding subunit of a calmodulin-dependent protein kinase. Journal of Neurochemistry. 42: 1077-84. PMID 6699638  1
1984 Taft WC, DeLorenzo RJ. Micromolar-affinity benzodiazepine receptors regulate voltage-sensitive calcium channels in nerve terminal preparations. Proceedings of the National Academy of Sciences of the United States of America. 81: 3118-22. PMID 6328498  1
1984 DeLorenzo RJ. Calmodulin systems in neuronal excitability: a molecular approach to epilepsy. Annals of Neurology. 16: S104-14. PMID 6150680  1
1984 Goldenring JR, Casanova JE, DeLorenzo RJ. Tubulin-associated calmodulin-dependent kinase: evidence for an endogenous complex of tubulin with a calcium-calmodulin-dependent kinase. Journal of Neurochemistry. 43: 1669-79. PMID 6092543  1
1983 Billingsley ML, Velletri PA, Roth RH, DeLorenzo RJ. Carboxylmethylation of calmodulin inhibits calmodulin-dependent phosphorylation in rat brain membranes and cytosol. The Journal of Biological Chemistry. 258: 5352-7. PMID 6853519  1
1983 DeLorenzo RJ. Calcium-calmodulin systems in psychopharmacology and synaptic modulation. Psychopharmacology Bulletin. 19: 393-7. PMID 6635112  1
1983 Goldenring JR, Gonzalez B, McGuire JS, DeLorenzo RJ. Purification and characterization of a calmodulin-dependent kinase from rat brain cytosol able to phosphorylate tubulin and microtubule-associated proteins. The Journal of Biological Chemistry. 258: 12632-40. PMID 6313669  1
1983 DeLorenzo RJ. Calcium-calmodulin protein phosphorylation in neuronal transmission: a molecular approach to neuronal excitability and anticonvulsant drug action. Advances in Neurology. 34: 325-38. PMID 6299072  1
1982 Delorenzo RJ, Gonzalez B, Goldenring J, Bowling A, Jacobson R. Ca2+-calmodulin tubulin kinase system and its role in mediating the Ca2+ signal in brain. Progress in Brain Research. 56: 257-86. PMID 6298873 DOI: 10.1016/S0079-6123(08)63779-6  1
1982 Goldenring JR, Gonzalez B, DeLorenzo RJ. Isolation of brain Ca2+-calmodulin tubulin kinase containing calmodulin binding proteins. Biochemical and Biophysical Research Communications. 108: 421-8. PMID 6293491 DOI: 10.1016/0006-291X(82)91883-6  1
1982 Bowling AC, DeLorenzo RJ. Micromolar affinity benzodiazepine receptors: identification and characterization in central nervous system. Science (New York, N.Y.). 216: 1247-50. PMID 6281893  1
1982 Burke BE, Delorenzo RJ. Ca2+ and calmodulin-regulated endogenous tubulin kinase activity in presynaptic nerve terminal preparations. Brain Research. 236: 393-415. PMID 6279244 DOI: 10.1016/0006-8993(82)90724-7  1
1982 DeLorenzo RJ. Calmodulin in neurotransmitter release and synaptic function. Federation Proceedings. 41: 2265-72. PMID 6122609  1
1982 Burke BE, DeLorenzo RJ. Ca2+ and calmodulin-dependent phosphorylation of endogenous synaptic vesicle tubulin by a vesicle-bound calmodulin kinase system. Journal of Neurochemistry. 38: 1205-18. PMID 6121008  1
1982 Bowling AC, DeLorenzo RJ. Anticonvulsant receptors: Identification and characterization in brain Neurology. 32: A 224.  1
1981 DeLorenzo RJ, Burdette S, Holderness J. Benzodiazepine inhibition of the calcium-calmodulin protein kinase system in brain membrane. Science (New York, N.Y.). 213: 546-9. PMID 6264605  1
1975 Walton KG, DeLorenzo RJ, Curran PF, Greengard P. Regulation of protein phosphorylation and sodium transport in toad bladder. The Journal of General Physiology. 65: 153-77. PMID 163889  1
1973 Delorenzo RJ, Greengard P. Activation by adenosine 3':5'-monophosphate of a membrane-bound phosphoprotein phosphatase from toad bladder. Proceedings of the National Academy of Sciences of the United States of America. 70: 1831-5. PMID 4352657  1
1973 DeLorenzo RJ, Walton KG, Curran PF, Greengard P. Regulation of phosphorylation of a specific protein in toad-bladder membrane by antidiuretic hormone and cyclic AMP, and its possible relationship to membrane permeability changes. Proceedings of the National Academy of Sciences of the United States of America. 70: 880-4. PMID 4351809  1
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