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Year Citation  Score
2018 Toma C, Pierce KD, Shaw AD, Heath A, Mitchell PB, Schofield PR, Fullerton JM. Comprehensive cross-disorder analyses of CNTNAP2 suggest it is unlikely to be a primary risk gene for psychiatric disorders. Plos Genetics. 14: e1007535. PMID 30586385 DOI: 10.1371/journal.pgen.1007535  0.52
2018 Toma C, Shaw AD, Allcock RJN, Heath A, Pierce KD, Mitchell PB, Schofield PR, Fullerton JM. An examination of multiple classes of rare variants in extended families with bipolar disorder. Translational Psychiatry. 8: 65. PMID 29531218 DOI: 10.1038/s41398-018-0113-y  0.52
2017 Salminen LE, Schofield PR, Pierce KD, Bruce SE, Griffin MG, Tate DF, Cabeen RP, Laidlaw DH, Conturo TE, Bolzenius JD, Paul RH. Vulnerability of white matter tracts and cognition to the SOD2 polymorphism: A preliminary study of antioxidant defense genes in brain aging. Behavioural Brain Research. PMID 28457881 DOI: 10.1016/j.bbr.2017.04.041  0.52
2016 Routledge KM, Burton KL, Williams LM, Harris A, Schofield PR, Clark CR, Gatt JM. The shared and unique genetic relationship between mental well-being, depression and anxiety symptoms and cognitive function in healthy twins. Cognition & Emotion. 1-15. PMID 27690266 DOI: 10.1080/02699931.2016.1232242  1
2016 Meiser B, Peate M, Levitan C, Mitchell PB, Trevena L, Barlow-Stewart K, Dobbins T, Christensen H, Sherman KA, Dunlop K, Schofield PR. A Psycho-Educational Intervention for People with a Family History of Depression: Pilot Results. Journal of Genetic Counseling. PMID 27688164 DOI: 10.1007/s10897-016-0011-5  1
2016 Lim YY, Hassenstab J, Cruchaga C, Goate A, Fagan AM, Benzinger TL, Maruff P, Snyder PJ, Masters CL, Allegri R, Chhatwal J, Farlow MR, Graff-Radford NR, Laske C, Levin J, ... ... Schofield PR, et al. BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease. Brain : a Journal of Neurology. PMID 27521573 DOI: 10.1093/brain/aww200  1
2016 Routledge KM, Burton KL, Williams LM, Harris A, Schofield PR, Clark CR, Gatt JM. Shared versus distinct genetic contributions of mental wellbeing with depression and anxiety symptoms in healthy twins. Psychiatry Research. 244: 65-70. PMID 27472172 DOI: 10.1016/j.psychres.2016.07.016  1
2016 Shiner CT, Pierce KD, Thompson-Butel AG, Trinh T, Schofield PR, McNulty PA. BDNF Genotype Interacts with Motor Function to Influence Rehabilitation Responsiveness Poststroke. Frontiers in Neurology. 7: 69. PMID 27242654 DOI: 10.3389/fneur.2016.00069  0.52
2016 Lee S, Viqar F, Zimmerman ME, Narkhede A, Tosto G, Benzinger TL, Marcus DS, Fagan AM, Goate A, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, ... ... Schofield PR, et al. White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the Dominantly Inherited Alzheimer Network. Annals of Neurology. PMID 27016429 DOI: 10.1002/ana.24647  1
2016 Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, ... ... Schofield PR, et al. Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. Plos One. 11: e0152082. PMID 27010959 DOI: 10.1371/journal.pone.0152082  1
2016 Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Banzato CE, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, ... ... Schofield PR, et al. Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Lancet (London, England). PMID 26806518 DOI: 10.1016/S0140-6736(16)00143-4  1
2015 Brautigam H, Moreno CL, Steele JW, Bogush A, Dickstein DL, Kwok JB, Schofield PR, Thinakaran G, Mathews PM, Hof PR, Gandy S, Ehrlich ME. Physiologically generated presenilin 1 lacking exon 8 fails to rescue brain PS1-/- phenotype and forms complexes with wildtype PS1 and nicastrin. Scientific Reports. 5: 17042. PMID 26608390 DOI: 10.1038/srep17042  1
2015 Forstner AJ, Hofmann A, Maaser A, Sumer S, Khudayberdiev S, Mühleisen TW, Leber M, Schulze TG, Strohmaier J, Degenhardt F, Treutlein J, Mattheisen M, Schumacher J, Breuer R, Meier S, ... ... Schofield PR, et al. Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder. Translational Psychiatry. 5: e678. PMID 26556287 DOI: 10.1038/tp.2015.159  1
2015 Burton KL, Williams LM, Richard Clark C, Harris A, Schofield PR, Gatt JM. Sex differences in the shared genetics of dimensions of self-reported depression and anxiety. Journal of Affective Disorders. 188: 35-42. PMID 26342886 DOI: 10.1016/j.jad.2015.08.053  1
2015 Salminen LE, Schofield PR, Pierce KD, Zhao Y, Luo X, Wang Y, Laidlaw DH, Cabeen RP, Conturo TE, Tate DF, Akbudak E, Lane EM, Heaps JM, Bolzenius JD, Baker LM, et al. Neuromarkers of the common angiotensinogen polymorphism in healthy older adults: A comprehensive assessment of white matter integrity and cognition. Behavioural Brain Research. PMID 26318936 DOI: 10.1016/j.bbr.2015.08.028  0.52
2015 Salminen LE, Schofield PR, Pierce KD, Luo X, Zhao Y, Laidlaw DH, Cabeen RP, Conturo TE, Lane EM, Heaps JM, Bolzenius JD, Baker LM, Cooley SA, Scott S, Cagle LM, et al. Genetic markers of cholesterol transport and gray matter diffusion: a preliminary study of the CETP I405V polymorphism. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 26253899 DOI: 10.1007/s00702-015-1434-0  0.52
2015 Wang F, Gordon BA, Ryman DC, Ma S, Xiong C, Hassenstab J, Goate A, Fagan AM, Cairns NJ, Marcus DS, McDade E, Ringman JM, Graff-Radford NR, Ghetti B, Farlow MR, ... ... Schofield PR, et al. Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease. Neurology. PMID 26245925 DOI: 10.1212/WNL.0000000000001903  1
2015 Dobson-Stone C, Shaw AD, Hallupp M, Bartley L, McCann H, Brooks WS, Loy CT, Schofield PR, Mather KA, Kochan NA, Sachdev PS, Halliday GM, Piguet O, Hodges JR, Kwok JB. Is CHCHD10 Pro34Ser pathogenic for frontotemporal dementia and amyotrophic lateral sclerosis? Brain : a Journal of Neurology. PMID 25953780 DOI: 10.1093/brain/awv115  1
2015 Chan JP, Thalamuthu A, Oldmeadow C, Armstrong NJ, Holliday EG, McEvoy M, Kwok JB, Assareh AA, Peel R, Hancock SJ, Reppermund S, Menant J, Trollor JN, Brodaty H, Schofield PR, et al. Genetics of hand grip strength in mid to late life. Age (Dordrecht, Netherlands). 37: 9745. PMID 25637336 DOI: 10.1007/s11357-015-9745-5  1
2015 Mather KA, Armstrong NJ, Wen W, Kwok JB, Assareh AA, Thalamuthu A, Reppermund S, Duesing K, Wright MJ, Ames D, Trollor JN, Brodaty H, Schofield PR, Sachdev PS. Investigating the genetics of hippocampal volume in older adults without dementia. Plos One. 10: e0116920. PMID 25625606 DOI: 10.1371/journal.pone.0116920  1
2015 Gatt JM, Burton KL, Williams LM, Schofield PR. Specific and common genes implicated across major mental disorders: a review of meta-analysis studies. Journal of Psychiatric Research. 60: 1-13. PMID 25287955 DOI: 10.1016/j.jpsychires.2014.09.014  1
2015 Salminen LE, Schofield PR, Pierce KD, Luo X, Zhao Y, Laidlaw DH, Cabeen RP, Conturo TE, Lane EM, Heaps JM, Bolzenius JD, Baker LM, Cooley SA, Scott S, Cagle LM, et al. Genetic markers of cholesterol transport and gray matter diffusion: a preliminary study of the CETP I405V polymorphism Journal of Neural Transmission. DOI: 10.1007/s00702-015-1434-0  1
2014 Kanchibhotla SC, Mather KA, Thalamuthu A, Zhuang L, Schofield PR, Kwok JB, Ames D, Wright MJ, Trollor JN, Wen W, Sachdev PS. Genetics of microstructure of the corpus callosum in older adults. Plos One. 9: e113181. PMID 25514436 DOI: 10.1371/journal.pone.0113181  1
2014 Myers AJ, Williams L, Gatt JM, McAuley-Clark EZ, Dobson-Stone C, Schofield PR, Nemeroff CB. Variation in the oxytocin receptor gene is associated with increased risk for anxiety, stress and depression in individuals with a history of exposure to early life stress. Journal of Psychiatric Research. 59: 93-100. PMID 25262417 DOI: 10.1016/j.jpsychires.2014.08.021  1
2014 Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM, Salloway S, McDade E, Rossor MN, ... ... Schofield PR, et al. Functional connectivity in autosomal dominant and late-onset Alzheimer disease. Jama Neurology. 71: 1111-22. PMID 25069482 DOI: 10.1001/jamaneurol.2014.1654  1
2014 Swift J, Saing S, Rouet R, Dudgeon K, Schofield P, Sewell W, Christ D. Identification of aggregation inhibitors of the human antibody light chain repertoire by phage display. Protein Engineering, Design & Selection : Peds. 27: 405-9. PMID 25053818 DOI: 10.1093/protein/gzu026  1
2014 Salminen LE, Schofield PR, Pierce KD, Conturo TE, Tate DF, Lane EM, Heaps JM, Bolzenius JD, Baker LM, Akbudak E, Paul RH. Impact of the AGTR1 A1166C polymorphism on subcortical hyperintensities and cognition in healthy older adults. Age (Dordrecht, Netherlands). 36: 9664. PMID 24981111 DOI: 10.1007/s11357-014-9664-x  1
2014 Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JB, Dobson-Stone C, Brooks WS, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, et al. Frontotemporal dementia and its subtypes: a genome-wide association study. The Lancet. Neurology. 13: 686-99. PMID 24943344 DOI: 10.1016/S1474-4422(14)70065-1  1
2014 Assareh AA, Piguet O, Lye TC, Mather KA, Broe GA, Schofield PR, Sachdev PS, Kwok JB. Association of SORL1 gene variants with hippocampal and cerebral atrophy and Alzheimer's disease. Current Alzheimer Research. 11: 558-63. PMID 24938503 DOI: 10.2174/1567205011666140618101408  1
2014 Ryman DC, Acosta-Baena N, Aisen PS, Bird T, Danek A, Fox NC, Goate A, Frommelt P, Ghetti B, Langbaum JB, Lopera F, Martins R, Masters CL, Mayeux RP, McDade E, ... ... Schofield PR, et al. Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis. Neurology. 83: 253-60. PMID 24928124 DOI: 10.1212/WNL.0000000000000596  1
2014 Oldmeadow C, Holliday EG, McEvoy M, Scott R, Kwok JB, Mather K, Sachdev P, Schofield P, Attia J. Concordance between direct and imputed APOE genotypes using 1000 Genomes data. Journal of Alzheimer's Disease : Jad. 42: 391-3. PMID 24903779 DOI: 10.3233/JAD-140846  1
2014 Gatt JM, Burton KL, Schofield PR, Bryant RA, Williams LM. The heritability of mental health and wellbeing defined using COMPAS-W, a new composite measure of wellbeing. Psychiatry Research. 219: 204-13. PMID 24863866 DOI: 10.1016/j.psychres.2014.04.033  1
2014 Sabouri Z, Schofield P, Horikawa K, Spierings E, Kipling D, Randall KL, Langley D, Roome B, Vazquez-Lombardi R, Rouet R, Hermes J, Chan TD, Brink R, Dunn-Walters DK, Christ D, et al. Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity. Proceedings of the National Academy of Sciences of the United States of America. 111: E2567-75. PMID 24821781 DOI: 10.1073/pnas.1406974111  1
2014 Zhou YZ, Wilde A, Meiser B, Mitchell PB, Barlow-Stewart K, Schofield PR. Attitudes of medical genetics practitioners and psychiatrists toward communicating with patients about genetic risk for psychiatric disorders. Psychiatric Genetics. 24: 94-101. PMID 24710128 DOI: 10.1097/YPG.0000000000000030  1
2014 Wilde A, Chan HN, Rahman B, Meiser B, Mitchell PB, Schofield PR, Green MJ. A meta-analysis of the risk of major affective disorder in relatives of individuals affected by major depressive disorder or bipolar disorder. Journal of Affective Disorders. 158: 37-47. PMID 24655763 DOI: 10.1016/j.jad.2014.01.014  1
2014 Shaw AD, Tiwari Y, Kaplan W, Heath A, Mitchell PB, Schofield PR, Fullerton JM. Characterisation of genetic variation in ST8SIA2 and its interaction region in NCAM1 in patients with bipolar disorder. Plos One. 9: e92556. PMID 24651862 DOI: 10.1371/journal.pone.0092556  1
2014 Assareh AA, Mather KA, Crawford JD, Wen W, Anstey KJ, Easteal S, Tan X, Mack HA, Kwok JB, Schofield PR, Sachdev PS. Renin-angiotensin system genetic polymorphisms and brain white matter lesions in older Australians. American Journal of Hypertension. 27: 1191-8. PMID 24622918 DOI: 10.1093/ajh/hpu035  1
2014 Mühleisen TW, Leber M, Schulze TG, Strohmaier J, Degenhardt F, Treutlein J, Mattheisen M, Forstner AJ, Schumacher J, Breuer R, Meier S, Herms S, Hoffmann P, Lacour A, Witt SH, ... ... Schofield PR, et al. Genome-wide association study reveals two new risk loci for bipolar disorder. Nature Communications. 5: 3339. PMID 24618891 DOI: 10.1038/ncomms4339  1
2014 Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benzinger TL, Ghetti B, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Salloway S, Schofield PR, Sperling RA, et al. Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease. Science Translational Medicine. 6: 226ra30. PMID 24598588 DOI: 10.1126/scitranslmed.3007901  1
2014 Vercammen A, Weickert CS, Skilleter AJ, Lenroot R, Schofield PR, Weickert TW. Common polymorphisms in dopamine-related genes combine to produce a 'schizophrenia-like' prefrontal hypoactivity. Translational Psychiatry. 4: e356. PMID 24495967 DOI: 10.1038/tp.2013.125  1
2014 Quinn V, Meiser B, Wilde A, Cousins Z, Barlow-Stewart K, Mitchell PB, Schofield PR. Preferences regarding targeted education and risk assessment in people with a family history of major depressive disorder. Journal of Genetic Counseling. 23: 785-95. PMID 24407933 DOI: 10.1007/s10897-013-9685-0  1
2014 Tadros MA, Farrell KE, Schofield PR, Brichta AM, Graham BA, Fuglevand AJ, Callister RJ. Intrinsic and synaptic homeostatic plasticity in motoneurons from mice with glycine receptor mutations. Journal of Neurophysiology. 111: 1487-98. PMID 24401707 DOI: 10.1152/jn.00728.2013  1
2014 Salminen LE, Schofield PR, Pierce KD, Lane EM, Heaps JM, Bolzenius JD, Baker LM, Luo X, Paul RH. Triallelic relationships between the serotonin transporter polymorphism and cognition among healthy older adults. The International Journal of Neuroscience. 124: 331-8. PMID 24044728 DOI: 10.3109/00207454.2013.845822  1
2014 Loy CT, Schofield PR, Turner AM, Kwok JB. Genetics of dementia. Lancet. 383: 828-40. PMID 23927914 DOI: 10.1016/S0140-6736(13)60630-3  1
2013 Meiser B, Schofield PR, Trevena L, Wilde A, Barlow-Stewart K, Proudfoot J, Peate M, Dobbins T, Christensen H, Sherman KA, Karatas J, Mitchell PB. Cluster randomized controlled trial of a psycho-educational intervention for people with a family history of depression for use in general practice. Bmc Psychiatry. 13: 325. PMID 24289740 DOI: 10.1186/1471-244X-13-325  1
2013 Benzinger TL, Blazey T, Jack CR, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, ... ... Schofield PR, et al. Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E4502-9. PMID 24194552 DOI: 10.1073/pnas.1317918110  1
2013 Cash DM, Ridgway GR, Liang Y, Ryan NS, Kinnunen KM, Yeatman T, Malone IB, Benzinger TL, Jack CR, Thompson PM, Ghetti BF, Saykin AJ, Masters CL, Ringman JM, Salloway SP, ... Schofield PR, et al. The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study. Neurology. 81: 1425-33. PMID 24049139 DOI: 10.1212/WNL.0b013e3182a841c6  1
2013 Mills SM, Mallmann J, Santacruz AM, Fuqua A, Carril M, Aisen PS, Althage MC, Belyew S, Benzinger TL, Brooks WS, Buckles VD, Cairns NJ, Clifford D, Danek A, Fagan AM, ... ... Schofield PR, et al. Preclinical trials in autosomal dominant AD: implementation of the DIAN-TU trial. Revue Neurologique. 169: 737-43. PMID 24016464 DOI: 10.1016/j.neurol.2013.07.017  1
2013 Dobson-Stone C, Polly P, Korgaonkar MS, Williams LM, Gordon E, Schofield PR, Mather K, Armstrong NJ, Wen W, Sachdev PS, Kwok JB. GSK3B and MAPT polymorphisms are associated with grey matter and intracranial volume in healthy individuals. Plos One. 8: e71750. PMID 23951236 DOI: 10.1371/journal.pone.0071750  1
2013 Chhatwal JP, Schultz AP, Johnson K, Benzinger TL, Jack C, Ances BM, Sullivan CA, Salloway SP, Ringman JM, Koeppe RA, Marcus DS, Thompson P, Saykin AJ, Correia S, Schofield PR, et al. Impaired default network functional connectivity in autosomal dominant Alzheimer disease. Neurology. 81: 736-44. PMID 23884042 DOI: 10.1212/WNL.0b013e3182a1aafe  1
2013 Manchia M, Adli M, Akula N, Ardau R, Aubry JM, Backlund L, Banzato CE, Baune BT, Bellivier F, Bengesser S, Biernacka JM, Brichant-Petitjean C, Bui E, Calkin CV, Cheng AT, ... ... Schofield PR, et al. Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report. Plos One. 8: e65636. PMID 23840348 DOI: 10.1371/journal.pone.0065636  1
2013 Dang TN, Dobson-Stone C, Glaros EN, Kim WS, Hallupp M, Bartley L, Piguet O, Hodges JR, Halliday GM, Double KL, Schofield PR, Crouch PJ, Kwok JB. Endogenous progesterone levels and frontotemporal dementia: modulation of TDP-43 and Tau levels in vitro and treatment of the A315T TARDBP mouse model. Disease Models & Mechanisms. 6: 1198-204. PMID 23798570 DOI: 10.1242/dmm.011460  1
2013 Xu M, Zou L, Wilde A, Meiser B, Barlow-Stewart K, Chan B, Mitchell PB, Sousa MS, Schofield PR. Exploring culture-specific differences in beliefs about causes, kinship and the heritability of major depressive disorder: the views of Anglo-Celtic and Chinese-Australians. Journal of Genetic Counseling. 22: 613-24. PMID 23681279 DOI: 10.1007/s10897-013-9593-3  1
2013 Bryant RA, Hung L, Dobson-Stone C, Schofield PR. The association between the oxytocin receptor gene (OXTR) and hypnotizability. Psychoneuroendocrinology. 38: 1979-84. PMID 23562248 DOI: 10.1016/j.psyneuen.2013.03.002  1
2013 Gatto D, Wood K, Caminschi I, Murphy-Durland D, Schofield P, Christ D, Karupiah G, Brink R. The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells Nature Immunology. 14: 446-453. PMID 23502855 DOI: 10.1038/ni.2555  1
2013 Salminen LE, Schofield PR, Lane EM, Heaps JM, Pierce KD, Cabeen R, Laidlaw DH, Akbudak E, Conturo TE, Correia S, Paul RH. Neuronal fiber bundle lengths in healthy adult carriers of the ApoE4 allele: a quantitative tractography DTI study. Brain Imaging and Behavior. 7: 274-81. PMID 23475756 DOI: 10.1007/s11682-013-9225-4  1
2013 Dobson-Stone C, Hallupp M, Loy CT, Thompson EM, Haan E, Sue CM, Panegyres PK, Razquin C, Seijo-Martínez M, Rene R, Gascon J, Campdelacreu J, Schmoll B, Volk AE, Brooks WS, ... Schofield PR, et al. C9ORF72 repeat expansion in Australian and Spanish frontotemporal dementia patients. Plos One. 8: e56899. PMID 23437264 DOI: 10.1371/journal.pone.0056899  1
2013 Dobson-Stone C, Luty AA, Thompson EM, Blumbergs P, Brooks WS, Short CL, Field CD, Panegyres PK, Hecker J, Solski JA, Blair IP, Fullerton JM, Halliday GM, Schofield PR, Kwok JB. Frontotemporal dementia-amyotrophic lateral sclerosis syndrome locus on chromosome 16p12.1-q12.2: genetic, clinical and neuropathological analysis. Acta Neuropathologica. 125: 523-33. PMID 23338750 DOI: 10.1007/s00401-013-1078-9  1
2013 Hsu SC, Sears RL, Lemos RR, Quintáns B, Huang A, Spiteri E, Nevarez L, Mamah C, Zatz M, Pierce KD, Fullerton JM, Adair JC, Berner JE, Bower M, Brodaty H, ... ... Schofield PR, et al. Mutations in SLC20A2 are a major cause of familial idiopathic basal ganglia calcification. Neurogenetics. 14: 11-22. PMID 23334463 DOI: 10.1007/s10048-012-0349-2  1
2013 Santarelli DM, Liu B, Duncan CE, Beveridge NJ, Tooney PA, Schofield PR, Cairns MJ. Gene-microRNA interactions associated with antipsychotic mechanisms and the metabolic side effects of olanzapine. Psychopharmacology. 227: 67-78. PMID 23318695 DOI: 10.1007/s00213-012-2939-y  1
2013 Felmingham KL, Dobson-Stone C, Schofield PR, Quirk GJ, Bryant RA. The brain-derived neurotrophic factor Val66Met polymorphism predicts response to exposure therapy in posttraumatic stress disorder. Biological Psychiatry. 73: 1059-63. PMID 23312562 DOI: 10.1016/j.biopsych.2012.10.033  1
2013 Spronk DB, Veth CP, Arns M, Schofield PR, Dobson-Stone C, Ramaekers JG, Franke B, de Bruijn ER, Verkes RJ. DBH -1021C>T and COMT Val108/158Met genotype are not associated with the P300 ERP in an auditory oddball task. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 124: 909-15. PMID 23261162 DOI: 10.1016/j.clinph.2012.11.008  1
2013 Kanchibhotla SC, Mather KA, Wen W, Schofield PR, Kwok JB, Sachdev PS. Genetics of ageing-related changes in brain white matter integrity - a review. Ageing Research Reviews. 12: 391-401. PMID 23128052 DOI: 10.1016/j.arr.2012.10.003  1
2013 Weickert CS, Fung SJ, Catts VS, Schofield PR, Allen KM, Moore LT, Newell KA, Pellen D, Huang XF, Catts SV, Weickert TW. Molecular evidence of N-methyl-D-aspartate receptor hypofunction in schizophrenia. Molecular Psychiatry. 18: 1185-92. PMID 23070074 DOI: 10.1038/mp.2012.137  1
2013 Wilde A, Mitchell PB, Meiser B, Schofield PR. Implications of the use of genetic tests in psychiatry, with a focus on major depressive disorder: a review. Depression and Anxiety. 30: 267-75. PMID 22987566 DOI: 10.1002/da.22000  1
2012 Porter MA, Dobson-Stone C, Kwok JB, Schofield PR, Beckett W, Tassabehji M. A role for transcription factor GTF2IRD2 in executive function in Williams-Beuren syndrome. Plos One. 7: e47457. PMID 23118870 DOI: 10.1371/journal.pone.0047457  1
2012 Li M, Wang Y, Zheng XB, Ikeda M, Iwata N, Luo XJ, Chong SA, Lee J, Rietschel M, Zhang F, Müller-Myhsok B, Cichon S, Weinberger DR, Mattheisen M, Schulze TG, ... ... Schofield PR, et al. Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility. Schizophrenia Research. 142: 200-5. PMID 23102693 DOI: 10.1016/j.schres.2012.10.008  1
2012 Wilhelm K, Gillis I, Reddy J, Mitchell PB, Campbell L, Dobson-Stone C, Pierce KD, Schofield PR. Association between serotonin transporter promoter polymorphisms and psychological distress in a diabetic population. Psychiatry Research. 200: 343-8. PMID 22921508 DOI: 10.1016/j.psychres.2012.07.008  1
2012 Dobson-Stone C, Hallupp M, Bartley L, Shepherd CE, Halliday GM, Schofield PR, Hodges JR, Kwok JB. C9ORF72 repeat expansion in clinical and neuropathologic frontotemporal dementia cohorts. Neurology. 79: 995-1001. PMID 22875086 DOI: 10.1212/WNL.0b013e3182684634  1
2012 Gatt JM, Korgaonkar MS, Schofield PR, Harris A, Clark CR, Oakley KL, Ram K, Michaelson H, Yap S, Stanners M, Wise V, Williams LM. The TWIN-E project in emotional wellbeing: study protocol and preliminary heritability results across four MRI and DTI measures. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 15: 419-41. PMID 22856376 DOI: 10.1017/thg.2012.12  1
2012 Weickert CS, Tiwari Y, Schofield PR, Mowry BJ, Fullerton JM. Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity. Translational Psychiatry. 2: e104. PMID 22832904 DOI: 10.1038/tp.2012.25  1
2012 Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, ... ... Schofield PR, et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. The New England Journal of Medicine. 367: 795-804. PMID 22784036 DOI: 10.1056/NEJMoa1202753  1
2012 Dudgeon K, Rouet R, Kokmeijer I, Schofield P, Stolp J, Langley D, Stock D, Christ D. General strategy for the generation of human antibody variable domains with increased aggregation resistance Proceedings of the National Academy of Sciences of the United States of America. 109: 10879-10884. PMID 22745168 DOI: 10.1073/pnas.1202866109  1
2012 Rahman B, Meiser B, Sachdev P, Barlow-Stewart K, Otlowski M, Zilliacus E, Schofield P. To know or not to know: An update of the literature on the psychological and behavioral impact of genetic testing for Alzheimer disease risk Genetic Testing and Molecular Biomarkers. 16: 935-942. PMID 22731638 DOI: 10.1089/gtmb.2011.0300  1
2012 McAuley EZ, Scimone A, Tiwari Y, Agahi G, Mowry BJ, Holliday EG, Donald JA, Weickert CS, Mitchell PB, Schofield PR, Fullerton JM. Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26. Plos One. 7: e38172. PMID 22693595 DOI: 10.1371/journal.pone.0038172  1
2012 Rouet R, Lowe D, Dudgeon K, Roome B, Schofield P, Langley D, Andrews J, Whitfeld P, Jermutus L, Christ D. Expression of high-affinity human antibody fragments in bacteria. Nature Protocols. 7: 364-73. PMID 22301775 DOI: 10.1038/nprot.2011.448  1
2011 Sachdev PS, Lee T, Lammel A, Crawford J, Trollor JN, Wright MJ, Brodaty H, Ames D, Martin NG. Cognitive functioning in older twins: the Older Australian Twins Study. Australasian Journal On Ageing. 30: 17-23. PMID 22032766 DOI: 10.1111/j.1741-6612.2011.00534.x  1
2011 Wilde A, Bonfiglioli C, Meiser B, Mitchell PB, Schofield PR. Portrayal of psychiatric genetics in Australian print news media, 1996-2009. The Medical Journal of Australia. 195: 401-4. PMID 21978348 DOI: 10.5694/mja10.10167  1
2011 Assareh A, Mather KA, Schofield PR, Kwok JB, Sachdev PS. The genetics of white matter lesions. Cns Neuroscience & Therapeutics. 17: 525-40. PMID 21951372 DOI: 10.1111/j.1755-5949.2010.00181.x  1
2011 Lowe D, Dudgeon K, Rouet R, Schofield P, Jermutus L, Christ D. Aggregation, stability, and formulation of human antibody therapeutics Advances in Protein Chemistry and Structural Biology. 84: 41-61. PMID 21846562 DOI: 10.1016/B978-0-12-386483-3.00004-5  1
2011 Wilde A, Meiser B, Mitchell PB, Schofield PR. Community attitudes to genetic susceptibility-based mental health interventions for healthy people in a large national sample. Journal of Affective Disorders. 134: 280-7. PMID 21763000 DOI: 10.1016/j.jad.2011.06.023  1
2011 O'Toole SA, Machalek DA, Shearer RF, Millar EK, Nair R, Schofield P, McLeod D, Cooper CL, McNeil CM, McFarland A, Nguyen A, Ormandy CJ, Qiu MR, Rabinovich B, Martelotto LG, et al. Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer. Cancer Research. 71: 4002-14. PMID 21632555 DOI: 10.1158/0008-5472.CAN-10-3738  1
2011 Graham BA, Tadros MA, Schofield PR, Callister RJ. Probing glycine receptor stoichiometry in superficial dorsal horn neurones using the spasmodic mouse. The Journal of Physiology. 589: 2459-74. PMID 21486794 DOI: 10.1113/jphysiol.2011.206326  1
2011 Cichon S, Mühleisen TW, Degenhardt FA, Mattheisen M, Miró X, Strohmaier J, Steffens M, Meesters C, Herms S, Weingarten M, Priebe L, Haenisch B, Alexander M, Vollmer J, Breuer R, ... ... Schofield PR, et al. Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. American Journal of Human Genetics. 88: 372-81. PMID 21353194 DOI: 10.1016/j.ajhg.2011.01.017  1
2011 Wilde A, Meiser B, Mitchell PB, Hadzi-Pavlovic D, Schofield PR. Community interest in predictive genetic testing for susceptibility to major depressive disorder in a large national sample. Psychological Medicine. 41: 1605-13. PMID 21159212 DOI: 10.1017/S0033291710002394  1
2011 Cichon S, Mühleisen TW, Degenhardt FA, Mattheisen M, Miró X, Strohmaier J, Steffens M, Meesters C, Herms S, Weingarten M, Priebe L, Haenisch B, Alexander M, Vollmer J, Breuer R, ... ... Schofield PR, et al. Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder (The American Journal of Human Genetics (2011) 88, (372-381)) American Journal of Human Genetics. 88: 396. DOI: 10.1016/j.ajhg.2011.03.001  1
2010 Luty AA, Kwok JB, Dobson-Stone C, Loy CT, Coupland KG, Karlström H, Sobow T, Tchorzewska J, Maruszak A, Barcikowska M, Panegyres PK, Zekanowski C, Brooks WS, Williams KL, Blair IP, ... ... Schofield PR, et al. Sigma nonopioid intracellular receptor 1 mutations cause frontotemporal lobar degeneration-motor neuron disease. Annals of Neurology. 68: 639-49. PMID 21031579 DOI: 10.1002/ana.22274  1
2010 Cederholm JM, Absalom NL, Sugiharto S, Griffith R, Schofield PR, Lewis TM. Conformational changes in extracellular loop 2 associated with signal transduction in the glycine receptor. Journal of Neurochemistry. 115: 1245-55. PMID 20874766 DOI: 10.1111/j.1471-4159.2010.07021.x  1
2010 Mitchell PB, Meiser B, Wilde A, Fullerton J, Donald J, Wilhelm K, Schofield PR. Predictive and diagnostic genetic testing in psychiatry. Clinics in Laboratory Medicine. 30: 829-46. PMID 20832655 DOI: 10.1016/j.cll.2010.07.001  1
2010 Gatt JM, Nemeroff CB, Schofield PR, Paul RH, Clark CR, Gordon E, Williams LM. Early life stress combined with serotonin 3A receptor and brain-derived neurotrophic factor valine 66 to methionine genotypes impacts emotional brain and arousal correlates of risk for depression. Biological Psychiatry. 68: 818-24. PMID 20728877 DOI: 10.1016/j.biopsych.2010.06.025  1
2010 Fullerton JM, Tiwari Y, Agahi G, Heath A, Berk M, Mitchell PB, Schofield PR. Assessing oxidative pathway genes as risk factors for bipolar disorder. Bipolar Disorders. 12: 550-6. PMID 20712757 DOI: 10.1111/j.1399-5618.2010.00834.x  1
2010 Gatt JM, Williams LM, Schofield PR, Dobson-Stone C, Paul RH, Grieve SM, Clark CR, Gordon E, Nemeroff CB. Impact of the HTR3A gene with early life trauma on emotional brain networks and depressed mood. Depression and Anxiety. 27: 752-9. PMID 20694966 DOI: 10.1002/da.20726  1
2010 Camp AJ, Lim R, Anderson WB, Schofield PR, Callister RJ, Brichta AM. Attenuated glycine receptor function reduces excitability of mouse medial vestibular nucleus neurons. Neuroscience. 170: 348-60. PMID 20600650 DOI: 10.1016/j.neuroscience.2010.06.040  1
2010 Bryant RA, Felmingham KL, Falconer EM, Pe Benito L, Dobson-Stone C, Pierce KD, Schofield PR. Preliminary evidence of the short allele of the serotonin transporter gene predicting poor response to cognitive behavior therapy in posttraumatic stress disorder. Biological Psychiatry. 67: 1217-9. PMID 20434135 DOI: 10.1016/j.biopsych.2010.03.016  1
2010 Mitchell PB, Meiser B, Wilde A, Fullerton J, Donald J, Wilhelm K, Schofield PR. Predictive and diagnostic genetic testing in psychiatry. The Psychiatric Clinics of North America. 33: 225-43. PMID 20159347 DOI: 10.1016/j.psc.2009.10.001  1
2010 Williams LM, Gatt JM, Grieve SM, Dobson-Stone C, Paul RH, Gordon E, Schofield PR. COMT Val(108/158)Met polymorphism effects on emotional brain function and negativity bias. Neuroimage. 53: 918-25. PMID 20139013 DOI: 10.1016/j.neuroimage.2010.01.084  1
2010 Fullerton JM, Donald JA, Mitchell PB, Schofield PR. Two-dimensional genome scan identifies multiple genetic interactions in bipolar affective disorder. Biological Psychiatry. 67: 478-86. PMID 20022591 DOI: 10.1016/j.biopsych.2009.10.022  1
2010 Wilde A, Meiser B, Mitchell PB, Schofield PR. Public interest in predictive genetic testing, including direct-to-consumer testing, for susceptibility to major depression: preliminary findings. European Journal of Human Genetics : Ejhg. 18: 47-51. PMID 19690586 DOI: 10.1038/ejhg.2009.138  1
2009 Wilde A, Meiser B, Mitchell PB, Schofield PR. Community attitudes towards mental health interventions for healthy people on the basis of genetic susceptibility. The Australian and New Zealand Journal of Psychiatry. 43: 1070-6. PMID 20001402 DOI: 10.3109/00048670903179152  1
2009 Sachdev PS, Lammel A, Trollor JN, Lee T, Wright MJ, Ames D, Wen W, Martin NG, Brodaty H, Schofield PR. A comprehensive neuropsychiatric study of elderly twins: the Older Australian Twins Study. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 12: 573-82. PMID 19943720 DOI: 10.1375/twin.12.6.573  1
2009 Duncan CE, Schofield PR, Weickert CS. K(v) channel interacting protein 3 expression and regulation by haloperidol in midbrain dopaminergic neurons. Brain Research. 1304: 1-13. PMID 19781530 DOI: 10.1016/j.brainres.2009.09.045  1
2009 McAuley EZ, Fullerton JM, Blair IP, Donald JA, Mitchell PB, Schofield PR. Association between the serotonin 2A receptor gene and bipolar affective disorder in an Australian cohort. Psychiatric Genetics. 19: 244-52. PMID 19584773 DOI: 10.1097/YPG.0b013e32832ceea9  1
2009 Williams LM, Gatt JM, Schofield PR, Olivieri G, Peduto A, Gordon E. 'Negativity bias' in risk for depression and anxiety: brain-body fear circuitry correlates, 5-HTT-LPR and early life stress. Neuroimage. 47: 804-14. PMID 19446647 DOI: 10.1016/j.neuroimage.2009.05.009  1
2009 Wilhelm K, Meiser B, Mitchell PB, Finch AW, Siegel JE, Parker G, Schofield PR. Issues concerning feedback about genetic testing and risk of depression. The British Journal of Psychiatry : the Journal of Mental Science. 194: 404-10. PMID 19407269 DOI: 10.1192/bjp.bp.107.047514  1
2009 Cederholm JM, Schofield PR, Lewis TM. Gating mechanisms in Cys-loop receptors. European Biophysics Journal : Ebj. 39: 37-49. PMID 19404635 DOI: 10.1007/s00249-009-0452-y  1
2009 Absalom NL, Schofield PR, Lewis TM. Pore structure of the Cys-loop ligand-gated ion channels. Neurochemical Research. 34: 1805-15. PMID 19381804 DOI: 10.1007/s11064-009-9971-2  1
2009 Williams LM, Gatt JM, Kuan SA, Dobson-Stone C, Palmer DM, Paul RH, Song L, Costa PT, Schofield PR, Gordon E. A polymorphism of the MAOA gene is associated with emotional brain markers and personality traits on an antisocial index. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1797-809. PMID 19194374 DOI: 10.1038/npp.2009.1  1
2009 Gatt JM, Nemeroff CB, Dobson-Stone C, Paul RH, Bryant RA, Schofield PR, Gordon E, Kemp AH, Williams LM. Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety. Molecular Psychiatry. 14: 681-95. PMID 19153574 DOI: 10.1038/mp.2008.143  1
2009 Schofield PR, Williams LM, Paul RH, Gatt JM, Brown K, Luty A, Cooper N, Grieve S, Dobson-Stone C, Morris C, Kuan SA, Gordon E. Disturbances in selective information processing associated with the BDNF Val66Met polymorphism: evidence from cognition, the P300 and fronto-hippocampal systems. Biological Psychology. 80: 176-88. PMID 18838100 DOI: 10.1016/j.biopsycho.2008.09.001  1
2009 Joffe RT, Gatt JM, Kemp AH, Grieve S, Dobson-Stone C, Kuan SA, Schofield PR, Gordon E, Williams LM. Brain derived neurotrophic factor Val66Met polymorphism, the five factor model of personality and hippocampal volume: Implications for depressive illness. Human Brain Mapping. 30: 1246-56. PMID 18548532 DOI: 10.1002/hbm.20592  1
2009 McAuley EZ, Blair IP, Liu Z, Fullerton JM, Scimone A, Van Herten M, Evans MR, Kirkby KC, Donald JA, Mitchell PB, Schofield PR. A genome screen of 35 bipolar affective disorder pedigrees provides significant evidence for a susceptibility locus on chromosome 15q25-26. Molecular Psychiatry. 14: 492-500. PMID 18227837 DOI: 10.1038/sj.mp.4002146  1
2009 Loy CT, Schofield PR, Kwok JBJ. Reply to García-Gorostiaga, et al Annals of Neurology. 65: 761-762. DOI: 10.1002/ana.21718  1
2008 Kwok JB, Loy CT, Hamilton G, Lau E, Hallupp M, Williams J, Owen MJ, Broe GA, Tang N, Lam L, Powell JF, Lovestone S, Schofield PR. Glycogen synthase kinase-3beta and tau genes interact in Alzheimer's disease. Annals of Neurology. 64: 446-54. PMID 18991351 DOI: 10.1002/ana.21476  1
2008 Duncan CE, Chetcuti AF, Schofield PR. Coregulation of genes in the mouse brain following treatment with clozapine, haloperidol, or olanzapine implicates altered potassium channel subunit expression in the mechanism of antipsychotic drug action. Psychiatric Genetics. 18: 226-39. PMID 18797397 DOI: 10.1097/YPG.0b013e3283053019  1
2008 Luty AA, Kwok JB, Thompson EM, Blumbergs P, Brooks WS, Loy CT, Dobson-Stone C, Panegyres PK, Hecker J, Nicholson GA, Halliday GM, Schofield PR. Pedigree with frontotemporal lobar degeneration--motor neuron disease and Tar DNA binding protein-43 positive neuropathology: genetic linkage to chromosome 9. Bmc Neurology. 8: 32. PMID 18755042 DOI: 10.1186/1471-2377-8-32  1
2008 Duffy L, Cappas E, Scimone A, Schofield PR, Karl T. Behavioral profile of a heterozygous mutant mouse model for EGF-like domain neuregulin 1. Behavioral Neuroscience. 122: 748-59. PMID 18729627 DOI: 10.1037/0735-7044.122.4.748  1
2008 Gatt JM, Kuan SA, Dobson-Stone C, Paul RH, Joffe RT, Kemp AH, Gordon E, Schofield PR, Williams LM. Association between BDNF Val66Met polymorphism and trait depression is mediated via resting EEG alpha band activity. Biological Psychology. 79: 275-84. PMID 18721847 DOI: 10.1016/j.biopsycho.2008.07.004  1
2008 Sugiharto S, Lewis TM, Moorhouse AJ, Schofield PR, Barry PH. Anion-cation permeability correlates with hydrated counterion size in glycine receptor channels. Biophysical Journal. 95: 4698-715. PMID 18708455 DOI: 10.1529/biophysj.107.125690  1
2008 Fullerton JM, Liu Z, Badenhop RF, Scimone A, Blair IP, Van Herten M, Donald JA, Mitchell PB, Schofield PR. Genome screen of 15 Australian bipolar affective disorder pedigrees supports previously identified loci for bipolar susceptibility genes. Psychiatric Genetics. 18: 156-61. PMID 18628676 DOI: 10.1097/YPG.0b013e3282fa1861  1
2008 Meiser B, Kasparian NA, Mitchell PB, Strong K, Simpson JM, Tabassum L, Mireskandari S, Schofield PR. Attitudes to genetic testing in families with multiple cases of bipolar disorder. Genetic Testing. 12: 233-43. PMID 18554164 DOI: 10.1089/gte.2007.0100  1
2008 Chetcuti A, Adams LJ, Mitchell PB, Schofield PR. Microarray gene expression profiling of mouse brain mRNA in a model of lithium treatment. Psychiatric Genetics. 18: 64-72. PMID 18349697 DOI: 10.1097/YPG.0b013e3282fb0051  1
2008 Chan DK, Mok V, Ng PW, Yeung J, Kwok JB, Fang ZM, Clarke R, Wong L, Schofield PR, Hattori N. PARK2 mutations and clinical features in a Chinese population with early-onset Parkinson's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 115: 715-9. PMID 18188499 DOI: 10.1007/s00702-007-0011-6  1
2008 Karlstrom H, Brooks WS, Kwok JB, Broe GA, Kril JJ, McCann H, Halliday GM, Schofield PR. Variable phenotype of Alzheimer's disease with spastic paraparesis. Journal of Neurochemistry. 104: 573-83. PMID 17995932 DOI: 10.1111/j.1471-4159.2007.05038.x  1
2007 Rademakers R, Baker M, Gass J, Adamson J, Huey ED, Momeni P, Spina S, Coppola G, Karydas AM, Stewart H, Johnson N, Hsiung GY, Kelley B, Kuntz K, Steinbart E, ... ... Schofield PR, et al. Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative. The Lancet. Neurology. 6: 857-68. PMID 17826340 DOI: 10.1016/S1474-4422(07)70221-1  1
2007 Wilhelm K, Siegel JE, Finch AW, Hadzi-Pavlovic D, Mitchell PB, Parker G, Schofield PR. The long and the short of it: associations between 5-HTT genotypes and coping with stress. Psychosomatic Medicine. 69: 614-20. PMID 17766691 DOI: 10.1097/PSY.0b013e31814cec64  1
2007 Graham BA, Brichta AM, Schofield PR, Callister RJ. Altered potassium channel function in the superficial dorsal horn of the spastic mouse. The Journal of Physiology. 584: 121-36. PMID 17690143 DOI: 10.1113/jphysiol.2007.138198  1
2007 Karlstrom H, Kwok JB, Gregory GC, Hallupp M, Brooks WS, Schofield PR. No association of spastic paraparesis genes in PSEN1 Alzheimer's disease with spastic paraparesis. Neuroreport. 18: 1267-9. PMID 17632280 DOI: 10.1097/WNR.0b013e3282405209  1
2007 Dobson-Stone C, Gatt JM, Kuan SA, Grieve SM, Gordon E, Williams LM, Schofield PR. Investigation of MCPH1 G37995C and ASPM A44871G polymorphisms and brain size in a healthy cohort. Neuroimage. 37: 394-400. PMID 17566767 DOI: 10.1016/j.neuroimage.2007.05.011  1
2007 Meiser B, Mitchell PB, Kasparian NA, Strong K, Simpson JM, Mireskandari S, Tabassum L, Schofield PR. Attitudes towards childbearing, causal attributions for bipolar disorder and psychological distress: a study of families with multiple cases of bipolar disorder. Psychological Medicine. 37: 1601-11. PMID 17537283 DOI: 10.1017/S0033291707000852  1
2007 Alexander DM, Williams LM, Gatt JM, Dobson-Stone C, Kuan SA, Todd EG, Schofield PR, Cooper NJ, Gordon E. The contribution of apolipoprotein E alleles on cognitive performance and dynamic neural activity over six decades. Biological Psychology. 75: 229-38. PMID 17433528 DOI: 10.1016/j.biopsycho.2007.03.001  1
2007 Boucher AA, Arnold JC, Duffy L, Schofield PR, Micheau J, Karl T. Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of Delta9-tetrahydrocannabinol. Psychopharmacology. 192: 325-36. PMID 17333138 DOI: 10.1007/s00213-007-0721-3  1
2007 Karl T, Duffy L, Scimone A, Harvey RP, Schofield PR. Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia. Genes, Brain, and Behavior. 6: 677-87. PMID 17309661 DOI: 10.1111/j.1601-183X.2006.00298.x  1
2007 Sinclair AH, Schofield PR. Human embryonic stem cell research: an Australian perspective. Cell. 128: 221-3. PMID 17254957 DOI: 10.1016/j.cell.2007.01.008  1
2007 Hickie IB, Naismith SL, Ward PB, Scott EM, Mitchell PB, Schofield PR, Scimone A, Wilhelm K, Parker G. Serotonin transporter gene status predicts caudate nucleus but not amygdala or hippocampal volumes in older persons with major depression. Journal of Affective Disorders. 98: 137-42. PMID 16930719 DOI: 10.1016/j.jad.2006.07.010  1
2006 Hoth KF, Paul RH, Williams LM, Dobson-Stone C, Todd E, Schofield PR, Gunstad J, Cohen RA, Gordon E. Associations between the COMT Val/Met polymorphism, early life stress, and personality among healthy adults. Neuropsychiatric Disease and Treatment. 2: 219-25. PMID 19412467 DOI: 10.2147/nedt.2006.2.2.219  1
2006 Pickering-Brown SM, Baker M, Gass J, Boeve BF, Loy CT, Brooks WS, Mackenzie IR, Martins RN, Kwok JB, Halliday GM, Kril J, Schofield PR, Mann DM, Hutton M. Mutations in progranulin explain atypical phenotypes with variants in MAPT. Brain : a Journal of Neurology. 129: 3124-6. PMID 17071927 DOI: 10.1093/brain/awl289  1
2006 Graham BA, Schofield PR, Sah P, Margrie TW, Callister RJ. Distinct physiological mechanisms underlie altered glycinergic synaptic transmission in the murine mutants spastic, spasmodic, and oscillator. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4880-90. PMID 16672662 DOI: 10.1523/JNEUROSCI.3991-05.2006  1
2006 Wilhelm K, Mitchell PB, Niven H, Finch A, Wedgwood L, Scimone A, Blair IP, Parker G, Schofield PR. Life events, first depression onset and the serotonin transporter gene. The British Journal of Psychiatry : the Journal of Mental Science. 188: 210-5. PMID 16507960 DOI: 10.1192/bjp.bp.105.009522  1
2006 Teber ET, Crawford E, Bolton KB, Van Dyk D, Schofield PR, Kapoor V, Church WB. Djinn Lite: a tool for customised gene transcript modelling, annotation-data enrichment and exploration. Bmc Bioinformatics. 7: 33. PMID 16426464 DOI: 10.1186/1471-2105-7-33  1
2006 Blair IP, Chetcuti AF, Badenhop RF, Scimone A, Moses MJ, Adams LJ, Craddock N, Green E, Kirov G, Owen MJ, Kwok JB, Donald JA, Mitchell PB, Schofield PR. Positional cloning, association analysis and expression studies provide convergent evidence that the cadherin gene FAT contains a bipolar disorder susceptibility allele. Molecular Psychiatry. 11: 372-83. PMID 16402135 DOI: 10.1038/sj.mp.4001784  1
2006 Chetcuti A, Adams LJ, Mitchell PB, Schofield PR. Altered gene expression in mice treated with the mood stabilizer sodium valproate. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 9: 267-76. PMID 15982445 DOI: 10.1017/S1461145705005717  1
2006 Gregory GC, Macdonald V, Schofield PR, Kril JJ, Halliday GM. Differences in regional brain atrophy in genetic forms of Alzheimer's disease. Neurobiology of Aging. 27: 387-93. PMID 15894410 DOI: 10.1016/j.neurobiolaging.2005.03.011  1
2005 Kwok JB, Hallupp M, Loy CT, Chan DK, Woo J, Mellick GD, Buchanan DD, Silburn PA, Halliday GM, Schofield PR. GSK3B polymorphisms alter transcription and splicing in Parkinson's disease. Annals of Neurology. 58: 829-39. PMID 16315267 DOI: 10.1002/ana.20691  1
2005 Panegyres PK, Kwok JB, Schofield PR, Blumbergs PC. A Western Australian kindred with Dutch cerebral amyloid angiopathy. Journal of the Neurological Sciences. 239: 75-80. PMID 16213528 DOI: 10.1016/j.jns.2005.08.002  1
2005 Blair IP, Badenhop RF, Scimone A, Moses MJ, Donald JA, Mitchell PB, Schofield PR. Identification, characterization, and association analysis of novel genes from the bipolar disorder susceptibility locus on chromosome 4q35. Psychiatric Genetics. 15: 199-204. PMID 16094255 DOI: 10.1097/00041444-200509000-00011  1
2005 Blair IP, Mitchell PB, Schofield PR. Techniques for the identification of genes involved in psychiatric disorders. The Australian and New Zealand Journal of Psychiatry. 39: 542-9. PMID 15996134 DOI: 10.1111/j.1440-1614.2005.01625.x  1
2005 Halliday GM, Song YJ, Lepar G, Brooks WS, Kwok JB, Kersaitis C, Gregory G, Shepherd CE, Rahimi F, Schofield PR, Kril JJ. Pick bodies in a family with presenilin-1 Alzheimer's disease. Annals of Neurology. 57: 139-43. PMID 15622541 DOI: 10.1002/ana.20366  1
2005 Meiser B, Mitchell PB, McGirr H, Van Herten M, Schofield PR. Implications of genetic risk information in families with a high density of bipolar disorder: an exploratory study. Social Science & Medicine (1982). 60: 109-18. PMID 15482871 DOI: 10.1016/j.socscimed.2004.04.016  1
2005 Dennis JA, Windsor PA, Schofield PR, Healy PJ. Bovine hyperekplexia Movement Disorders. 479-486. DOI: 10.1016/B978-012088382-0/50044-X  1
2004 Piguet O, Brooks WS, Halliday GM, Schofield PR, Stanford PM, Kwok JB, Spillantini MG, Yancopoulou D, Nestor PJ, Broe GA, Hodges JR. Similar early clinical presentations in familial and non-familial frontotemporal dementia. Journal of Neurology, Neurosurgery, and Psychiatry. 75: 1743-5. PMID 15548495 DOI: 10.1136/jnnp.2003.031948  1
2004 Brooks WS, Kwok JB, Halliday GM, Godbolt AK, Rossor MN, Creasey H, Jones AO, Schofield PR. Hemorrhage is uncommon in new Alzheimer family with Flemish amyloid precursor protein mutation. Neurology. 63: 1613-7. PMID 15534244  1
2004 Stanford PM, Brooks WS, Teber ET, Hallupp M, McLean C, Halliday GM, Martins RN, Kwok JB, Schofield PR. Frequency of tau mutations in familial and sporadic frontotemporal dementia and other tauopathies. Journal of Neurology. 251: 1098-104. PMID 15372253 DOI: 10.1007/s00415-004-0489-x  1
2004 Morris R, Morgan BS, Lewis TM, Pierce KD, Pisano A, Schofield PR. In vivo somatic delivery of plasmid DNA and retrograde transport to obtain cell-specific gene expression in the central nervous system. Journal of Neurochemistry. 90: 1445-52. PMID 15341528 DOI: 10.1111/j.1471-4159.2004.02612.x  1
2004 Keramidas A, Moorhouse AJ, Schofield PR, Barry PH. Ligand-gated ion channels: mechanisms underlying ion selectivity. Progress in Biophysics and Molecular Biology. 86: 161-204. PMID 15288758 DOI: 10.1016/j.pbiomolbio.2003.09.002  1
2004 Badenhop RF, Jansen JC, Fagan PA, Lord RS, Wang ZG, Foster WJ, Schofield PR. The prevalence of SDHB, SDHC, and SDHD mutations in patients with head and neck paraganglioma and association of mutations with clinical features. Journal of Medical Genetics. 41: e99. PMID 15235042  1
2004 Absalom NL, Lewis TM, Schofield PR. Mechanisms of channel gating of the ligand-gated ion channel superfamily inferred from protein structure. Experimental Physiology. 89: 145-53. PMID 15123543 DOI: 10.1113/expphysiol.2003.026815  1
2004 Verdile G, Groth D, Mathews PM, St George-Hyslop P, Fraser PE, Ramabhadran TV, Kwok JB, Schofield PR, Carter T, Gandy S, Martins RN. Baculoviruses expressing the human familial Alzheimer's disease presenilin 1 mutation lacking exon 9 increase levels of an amyloid beta-like protein in Sf9 cells. Molecular Psychiatry. 9: 594-602. PMID 14993906 DOI: 10.1038/sj.mp.4001458  1
2004 Kwok JB, Teber ET, Loy C, Hallupp M, Nicholson G, Mellick GD, Buchanan DD, Silburn PA, Schofield PR. Tau haplotypes regulate transcription and are associated with Parkinson's disease. Annals of Neurology. 55: 329-34. PMID 14991810 DOI: 10.1002/ana.10826  1
2004 Shepherd CE, Gregory GC, Vickers JC, Brooks WS, Kwok JB, Schofield PR, Kril JJ, Halliday GM. Positional effects of presenilin-1 mutations on tau phosphorylation in cortical plaques. Neurobiology of Disease. 15: 115-9. PMID 14751776 DOI: 10.1016/j.nbd.2003.10.008  1
2003 Lee DJ, Keramidas A, Moorhouse AJ, Schofield PR, Barry PH. The contribution of proline 250 (P-2') to pore diameter and ion selectivity in the human glycine receptor channel. Neuroscience Letters. 351: 196-200. PMID 14623139 DOI: 10.1016/j.neulet.2003.08.005  1
2003 Mitchell PB, Schofield PR, Donald JA. Major leads in the search for susceptibility genes for depression. The Pharmacogenomics Journal. 3: 305-7. PMID 14610522 DOI: 10.1038/sj.tpj.6500212  1
2003 Absalom NL, Lewis TM, Kaplan W, Pierce KD, Schofield PR. Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor. The Journal of Biological Chemistry. 278: 50151-7. PMID 14525990 DOI: 10.1074/jbc.M305357200  1
2003 Graham BA, Schofield PR, Sah P, Callister RJ. Altered inhibitory synaptic transmission in superficial dorsal horn neurones in spastic and oscillator mice. The Journal of Physiology. 551: 905-16. PMID 12837931 DOI: 10.1113/jphysiol.2003.049064  1
2003 Segurado R, Detera-Wadleigh SD, Levinson DF, Lewis CM, Gill M, Nurnberger JI, Craddock N, DePaulo JR, Baron M, Gershon ES, Ekholm J, Cichon S, Turecki G, Claes S, Kelsoe JR, ... Schofield PR, et al. Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. American Journal of Human Genetics. 73: 49-62. PMID 12802785 DOI: 10.1086/376547  1
2003 Lewis TM, Schofield PR, McClellan AM. Kinetic determinants of agonist action at the recombinant human glycine receptor. The Journal of Physiology. 549: 361-74. PMID 12679369 DOI: 10.1113/jphysiol.2002.037796  1
2003 Brooks WS, Kwok JB, Kril JJ, Broe GA, Blumbergs PC, Tannenberg AE, Lamont PJ, Hedges P, Schofield PR. Alzheimer's disease with spastic paraparesis and 'cotton wool' plaques: two pedigrees with PS-1 exon 9 deletions. Brain : a Journal of Neurology. 126: 783-91. PMID 12615638 DOI: 10.1093/brain/awg084  1
2003 Badenhop RF, Moses MJ, Scimone A, Adams LJ, Kwok JB, Jones AM, Davison G, Evans MR, Kirkby KC, Hewitt JE, Donald JA, Mitchell PB, Schofield PR. Genetic refinement and physical mapping of a 2.3 Mb probable disease region associated with a bipolar affective disorder susceptibility locus on chromosome 4q35. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 117: 23-32. PMID 12555231 DOI: 10.1002/ajmg.b.10023  1
2003 Kwok JB, Halliday GM, Brooks WS, Dolios G, Laudon H, Murayama O, Hallupp M, Badenhop RF, Vickers J, Wang R, Naslund J, Takashima A, Gandy SE, Schofield PR. Presenilin-1 mutation L271V results in altered exon 8 splicing and Alzheimer's disease with non-cored plaques and no neuritic dystrophy. The Journal of Biological Chemistry. 278: 6748-54. PMID 12493737 DOI: 10.1074/jbc.M211827200  1
2002 Healy PJ, Dennis JA, Windsor PA, Pierce KD, Schofield PR. Genotyping cattle for inherited congenital myoclonus and maple syrup urine disease Australian Veterinary Journal. 80: 695-697. PMID 12465829  1
2002 Blair IP, Adams LJ, Badenhop RF, Moses MJ, Scimone A, Morris JA, Ma L, Austin CP, Donald JA, Mitchell PB, Schofield PR. A transcript map encompassing a susceptibility locus for bipolar affective disorder on chromosome 4q35. Molecular Psychiatry. 7: 867-73. PMID 12232780 DOI: 10.1038/sj.mp.4001113  1
2002 Badenhop RF, Moses MJ, Scimone A, Mitchell PB, Ewen-White KR, Rosso A, Donald JA, Adams LJ, Schofield PR. A genome screen of 13 bipolar affective disorder pedigrees provides evidence for susceptibility loci on chromosome 3 as well as chromosomes 9, 13 and 19. Molecular Psychiatry. 7: 851-9. PMID 12232778 DOI: 10.1038/sj.mp.4001114  1
2002 Blair IP, Adam LJ, Badenhop RF, Moses MJ, Scimone A, Morris JA, Ma L, Austin CP, Donald JA, Mitchell PB, Schofield PR. Stylized transcript map of chromosome 4q35 encompassing the locus for a bipolar disorder susceptibility gene. Molecular Psychiatry. 7: 669. PMID 12192607 DOI: 10.1038/sj.mp.4001154  1
2002 Kwok JB, Kapoor R, Gotoda T, Iwamoto Y, Iizuka Y, Yamada N, Isaacs KE, Kushwaha VV, Church WB, Schofield PR, Kapoor V. A missense mutation in kynurenine aminotransferase-1 in spontaneously hypertensive rats. The Journal of Biological Chemistry. 277: 35779-82. PMID 12145272 DOI: 10.1074/jbc.C200303200  1
2002 Badenhop RF, Moses MJ, Scimone A, Mitchell PB, Ewen-White KR, Rosso A, Donald JA, Adams LJ, Schofield PR. A genome screen of 13 bipolar affective disorder pedigrees provides evidence for susceptibility loci on chromosome 3 as well as chromosomes 9, 13 and 19. Molecular Psychiatry. 7: 594-603. PMID 12140782 DOI: 10.1038/sj.mp.4001025  1
2002 Moorhouse AJ, Keramidas A, Zaykin A, Schofield PR, Barry PH. Single channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channels. The Journal of General Physiology. 119: 411-25. PMID 11981021 DOI: 10.1085/jgp.20028553  1
2002 Keramidas A, Moorhouse AJ, Pierce KD, Schofield PR, Barry PH. Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity. The Journal of General Physiology. 119: 393-410. PMID 11981020 DOI: 10.1085/jgp.20028552  1
2002 Münch G, Shepherd CE, McCann H, Brooks WS, Kwok JB, Arendt T, Hallupp M, Schofield PR, Martins RN, Halliday GM. Intraneuronal advanced glycation endproducts in presenilin-1 Alzheimer's disease. Neuroreport. 13: 601-4. PMID 11973454  1
2002 Schofield PR. The role of glycine and glycine receptors in myoclonus and startle syndromes. Advances in Neurology. 89: 263-74. PMID 11968453  1
2002 Rees MI, Lewis TM, Kwok JB, Mortier GR, Govaert P, Snell RG, Schofield PR, Owen MJ. Hyperekplexia associated with compound heterozygote mutations in the beta-subunit of the human inhibitory glycine receptor (GLRB). Human Molecular Genetics. 11: 853-60. PMID 11929858  1
2002 Brodaty H, Mitchell P, Luscombe G, Kwok JJ, Badenhop RF, McKenzie R, Schofield PR. Familial idiopathic basal ganglia calcification (Fahr's disease) without neurological, cognitive and psychiatric symptoms is not linked to the IBGC1 locus on chromosome 14q. Human Genetics. 110: 8-14. PMID 11810290 DOI: 10.1007/s00439-001-0650-x  1
2002 Healy PJ, Pierce KD, Dennis JA, Windsor PA, Schofield PR. Bovine myoclonus: Model of human hyperekplexia (startle disease) Movement Disorders. 17: 743-744. DOI: 10.1002/mds.10216  1
2001 Rees MI, Lewis TM, Vafa B, Ferrie C, Corry P, Muntoni F, Jungbluth H, Stephenson JB, Kerr M, Snell RG, Schofield PR, Owen MJ. Compound heterozygosity and nonsense mutations in the alpha(1)-subunit of the inhibitory glycine receptor in hyperekplexia. Human Genetics. 109: 267-70. PMID 11702206 DOI: 10.1007/s004390100569  1
2001 Badenhop RF, Moses MJ, Scimone A, Mitchell PB, Ewen KR, Rosso A, Donald JA, Adams LJ, Schofield PR. A genome screen of a large bipolar affective disorder pedigree supports evidence for a susceptibility locus on chromosome 13q. Molecular Psychiatry. 6: 396-403. PMID 11443523 DOI: 10.1038/sj.mp.4000887  1
2001 Collie A, Maruff P, Shafiq-Antonacci R, Smith M, Hallup M, Schofield PR, Masters CL, Currie J. Memory decline in healthy older people: implications for identifying mild cognitive impairment. Neurology. 56: 1533-8. PMID 11402111  1
2001 Badenhop RF, Cherian S, Lord RS, Baysal BE, Taschner PE, Schofield PR. Novel mutations in the SDHD gene in pedigrees with familial carotid body paraganglioma and sensorineural hearing loss. Genes, Chromosomes & Cancer. 31: 255-63. PMID 11391796 DOI: 10.1002/gcc.1142  1
2001 Kwok JB, Raskin S, Morgan G, Antoniuk SA, Bruk I, Schofield PR. Mutations in the glycine receptor alpha1 subunit (GLRA1) gene in hereditary hyperekplexia pedigrees: evidence for non-penetrance of mutation Y279C. Journal of Medical Genetics. 38: E17. PMID 11389164  1
2001 Lynch JW, Han NL, Haddrill J, Pierce KD, Schofield PR. The surface accessibility of the glycine receptor M2-M3 loop is increased in the channel open state. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 2589-99. PMID 11306612  1
2001 Smith MJ, Kwok JB, McLean CA, Kril JJ, Broe GA, Nicholson GA, Cappai R, Hallupp M, Cotton RG, Masters CL, Schofield PR, Brooks WS. Variable phenotype of Alzheimer's disease with spastic paraparesis. Annals of Neurology. 49: 125-9. PMID 11198283 DOI: 10.1002/1531-8249(200101)49:1<125::AID-ANA21>3.0.CO;2-1  1
2001 Pierce KD, Handford CA, Morris R, Vafa B, Dennis JA, Healy PJ, Schofield PR. A nonsense mutation in the alpha1 subunit of the inhibitory glycine receptor associated with bovine myoclonus. Molecular and Cellular Neurosciences. 17: 354-63. PMID 11178872 DOI: 10.1006/mcne.2000.0934  1
2001 Schofield PR. Genetics, an alternative way to discover, characterize and understand ion channels. Clinical and Experimental Pharmacology & Physiology. 28: 84-8. PMID 11153544 DOI: 10.1046/j.1440-1681.2001.03409.x  1
2001 Badenhop RF, Moses MJ, Scimone A, Adams LJ, Donald JA, Mitchell PB, Schofield PR. Haplotype analysis defines a 4.7Mb probable disease region for a bipolar affective disorder susceptibility locus on chromosome 4q35 American Journal of Medical Genetics - Neuropsychiatric Genetics. 105: 591.  1
2001 Adams LJ, Schofield PR. Microarray studies of changes in gene expression in mouse brain induced by anti-manic drugs American Journal of Medical Genetics - Neuropsychiatric Genetics. 105: 582-583.  1
2000 Keramidas A, Moorhouse AJ, French CR, Schofield PR, Barry PH. M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective. Biophysical Journal. 79: 247-59. PMID 10866951 DOI: 10.1016/S0006-3495(00)76287-4  1
2000 Stanford PM, Halliday GM, Brooks WS, Kwok JB, Storey CE, Creasey H, Morris JG, Fulham MJ, Schofield PR. Progressive supranuclear palsy pathology caused by a novel silent mutation in exon 10 of the tau gene: expansion of the disease phenotype caused by tau gene mutations. Brain : a Journal of Neurology. 123: 880-93. PMID 10775534  1
2000 Kwok JB, Li QX, Hallupp M, Whyte S, Ames D, Beyreuther K, Masters CL, Schofield PR. Novel Leu723Pro amyloid precursor protein mutation increases amyloid beta42(43) peptide levels and induces apoptosis. Annals of Neurology. 47: 249-53. PMID 10665499 DOI: 10.1002/1531-8249(200002)47:2<249::AID-ANA18>3.0.CO;2-8  1
2000 Badenhop RF, Moses MJ, Mitchell PB, Donald JA, Adams LJ, Schofield PR. A genome-wide screen for bipolar affective disorder susceptibility loci from 13 Australian pedigrees American Journal of Medical Genetics - Neuropsychiatric Genetics. 96: 548-549.  1
2000 Adams LJ, Badenhop RF, Morris JA, Moses MJ, Scimone A, Ma L, Jones AM, Mathavan K, Donald JA, Hewitt JE, Detera-Wadleigh SD, Mitchell PB, Austin CP, Schofield PR. Analysis of a bipolar affective disorder susceptibility locus on chromosome 4q35 American Journal of Medical Genetics - Neuropsychiatric Genetics. 96: 469.  1
1999 Barry PH, Schofield PR, Moorhouse AJ. Glycine receptors: what gets in and why? Clinical and Experimental Pharmacology & Physiology. 26: 935-6. PMID 10561819  0.52
1999 Lynch JW, Han NI, Schofield PR. Building new function into glycine receptors: a structural model for the activation of the glycine-gated chloride channel. Clinical and Experimental Pharmacology & Physiology. 26: 932-4. PMID 10561818 DOI: 10.1046/j.1440-1681.1999.03150.x  1
1999 Callister RJ, Schofield PR, Sah P. Use of murine mutants to study glycine receptor function. Clinical and Experimental Pharmacology & Physiology. 26: 929-31. PMID 10561817 DOI: 10.1046/j.1440-1681.1999.03148.x  1
1999 Vafa B, Lewis TM, Cunningham AM, Jacques P, Lynch JW, Schofield PR. Identification of a new ligand binding domain in the alpha1 subunit of the inhibitory glycine receptor. Journal of Neurochemistry. 73: 2158-66. PMID 10537076  1
1999 Lewis TM, Schofield PR. Structure-function relationships of the human glycine receptor: insights from hyperekplexia mutations. Annals of the New York Academy of Sciences. 868: 681-4. PMID 10414353 DOI: 10.1111/j.1749-6632.1999.tb11345.x  1
1999 Kwok JB, Adams LJ, Salmon JA, Donald JA, Mitchell PB, Schofield PR. Nonparametric simulation-based statistical analyses for bipolar affective disorder locus on chromosome 21q22.3. American Journal of Medical Genetics. 88: 99-102. PMID 10050976 DOI: 10.1002/(SICI)1096-8628(19990205)88:1<99::AID-AJMG18>3.0.CO;2-9  1
1999 Moorhouse AJ, Jacques P, Barry PH, Schofield PR. The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gating. Molecular Pharmacology. 55: 386-95. PMID 9927632  0.52
1999 Laws SM, Taddei K, Fisher C, Small D, Clarnette R, Hallmayer J, Brooks WS, Kwok JBJ, Schofield PR, Gandy SE, Martins RN. Evidence that the butyryl-cholinesterase K variant can protect against late-onset Alzheimer's disease Alzheimer's Reports. 2: 219-223.  1
1999 Verdile G, Fraser PE, Schofield PR, Fisher C, Helmerhorst E, Martins RN. Decreased secretion of amyloid precursor protein in Chinese hamster ovary cells overexpressing presenilin 1 Alzheimer's Reports. 2: 231-239.  1
1998 Camp D, Green JM, Kaiser SM, Moni RW, Townsend-Nicholson A, Schofield PR, Quinn RJ. Diimidazo[1,2-c:4',5'-e]pyrimidines: adenosine agonist activity demonstrated by microphysiometry. Bioorganic & Medicinal Chemistry Letters. 8: 691-4. PMID 9871584 DOI: 10.1016/S0960-894X(98)00102-4  1
1998 Lynch JW, Jacques P, Pierce KD, Schofield PR. Zinc potentiation of the glycine receptor chloride channel is mediated by allosteric pathways. Journal of Neurochemistry. 71: 2159-68. PMID 9798943  0.52
1998 Hutton M, Lendon CL, Rizzu P, Baker M, Froelich S, Houlden H, Pickering-Brown S, Chakraverty S, Isaacs A, Grover A, Hackett J, Adamson J, Lincoln S, Dickson D, Davies P, ... ... Schofield PR, et al. Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17. Nature. 393: 702-5. PMID 9641683 DOI: 10.1038/31508  1
1998 Adams LJ, Mitchell PB, Fielder SL, Rosso A, Donald JA, Schofield PR. A susceptibility locus for bipolar affective disorder on chromosome 4q35. American Journal of Human Genetics. 62: 1084-91. PMID 9545396 DOI: 10.1086/301826  1
1998 Vafa B, Schofield PR. Heritable mutations in the glycine, GABAA, and nicotinic acetylcholine receptors provide new insights into the ligand-gated ion channel receptor superfamily. International Review of Neurobiology. 42: 285-332. PMID 9476176  0.44
1997 Donald JA, Salmon JA, Adams LJ, Littlejohn T, Maher A, Mitchell PB, Schofield PR. Parental sex effects in bipolar affective disorder pedigrees. Genetic Epidemiology. 14: 611-6. PMID 9433551 DOI: 10.1002/(SICI)1098-2272(1997)14:6<611::AID-GEPI10>3.0.CO;2-T  1
1997 Adams LJ, Salmon JA, Kwok JB, Vivero C, Donald JA, Mitchell PB, Schofield PR. Exclusion of linkage between bipolar affective disorder and chromosome 16 in 12 Australian pedigrees. American Journal of Medical Genetics. 74: 304-10. PMID 9184315 DOI: 10.1002/(SICI)1096-8628(19970531)74:3<304::AID-AJMG12>3.0.CO;2-S  1
1997 Kwok JB, Taddei K, Hallupp M, Fisher C, Brooks WS, Broe GA, Hardy J, Fulham MJ, Nicholson GA, Stell R, St George Hyslop PH, Fraser PE, Kakulas B, Clarnette R, Relkin N, ... ... Schofield PR, et al. Two novel (M233T and R278T) presenilin-1 mutations in early-onset Alzheimer's disease pedigrees and preliminary evidence for association of presenilin-1 mutations with a novel phenotype. Neuroreport. 8: 1537-42. PMID 9172170  1
1997 Valenzuela SM, Martin DK, Por SB, Robbins JM, Warton K, Bootcov MR, Schofield PR, Campbell TJ, Breit SN. Molecular cloning and expression of a chloride ion channel of cell nuclei. The Journal of Biological Chemistry. 272: 12575-82. PMID 9139710 DOI: 10.1074/jbc.272.19.12575  1
1997 Lynch JW, Rajendra S, Pierce KD, Handford CA, Barry PH, Schofield PR. Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel. The Embo Journal. 16: 110-20. PMID 9009272 DOI: 10.1093/emboj/16.1.110  0.52
1996 Schofield PR, Lynch JW, Rajendra S, Pierce KD, Handford CA, Barry PH. Molecular and genetic insights into ligand binding and signal transduction at the inhibitory glycine receptor. Cold Spring Harbor Symposia On Quantitative Biology. 61: 333-42. PMID 9246463  0.52
1996 Adams LJ, Salmon J, Donald JA, Mitchell PB, Schofield PR. Nonlinkage of D6S260, a putative schizophrenia locus, to bipolar affective disorder. American Journal of Medical Genetics. 67: 485-7. PMID 8886167 DOI: 10.1002/(SICI)1096-8628(19960920)67:5<485::AID-AJMG9>3.0.CO;2-J  1
1996 Handford CA, Lynch JW, Baker E, Webb GC, Ford JH, Sutherland GR, Schofield PR. The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes. Brain Research. Molecular Brain Research. 35: 211-9. PMID 8717357 DOI: 10.1016/0169-328X(95)00218-H  1
1996 Mascia MP, Mihic SJ, Valenzuela CF, Schofield PR, Harris RA. A single amino acid determines differences in ethanol actions on strychnine-sensitive glycine receptors. Molecular Pharmacology. 50: 402-6. PMID 8700149  1
1995 Rajendra S, Lynch JW, Pierce KD, French CR, Barry PH, Schofield PR. Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonists. Neuron. 14: 169-75. PMID 7826634  0.52
1995 Lynch JW, Rajendra S, Barry PH, Schofield PR. Mutations affecting the glycine receptor agonist transduction mechanism convert the competitive antagonist, picrotoxin, into an allosteric potentiator. The Journal of Biological Chemistry. 270: 13799-806. PMID 7775436  0.52
1995 Rajendra S, Vandenberg RJ, Pierce KD, Cunningham AM, French PW, Barry PH, Schofield PR. The unique extracellular disulfide loop of the glycine receptor is a principal ligand binding element. The Embo Journal. 14: 2987-98. PMID 7621814  1
1995 Grossmann M, Szkudlinski MW, Tropea JE, Bishop LA, Thotakura NR, Schofield PR, Weintraub BD. Expression of human thyrotropin in cell lines with different glycosylation patterns combined with mutagenesis of specific glycosylation sites. Characterization of a novel role for the oligosaccharides in the in vitro and in vivo bioactivity. The Journal of Biological Chemistry. 270: 29378-85. PMID 7493973  1
1994 Rajendra S, Lynch JW, Pierce KD, French CR, Barry PH, Schofield PR. Startle disease mutations reduce the agonist sensitivity of the human inhibitory glycine receptor. The Journal of Biological Chemistry. 269: 18739-42. PMID 7518444  0.52
1993 Vandenberg RJ, Rajendra S, French CR, Barry PH, Schofield PR. The extracellular disulfide loop motif of the inhibitory glycine receptor does not form the agonist binding site. Molecular Pharmacology. 44: 198-203. PMID 8393521  1
1992 Vandenberg RJ, Handford CA, Schofield PR. Distinct agonist- and antagonist-binding sites on the glycine receptor. Neuron. 9: 491-6. PMID 1326295 DOI: 10.1016/0896-6273(92)90186-H  1
1992 Vandenberg RJ, French CR, Barry PH, Shine J, Schofield PR. Antagonism of ligand-gated ion channel receptors: two domains of the glycine receptor alpha subunit form the strychnine-binding site. Proceedings of the National Academy of Sciences of the United States of America. 89: 1765-9. PMID 1311851  1
1991 Braun T, Schofield PR, Sprengel R. Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity. The Embo Journal. 10: 1885-90. PMID 2050124  1
1990 Ymer S, Draguhn A, Wisden W, Werner P, Keinänen K, Schofield PR, Sprengel R, Pritchett DB, Seeburg PH. Structural and functional characterization of the gamma 1 subunit of GABAA/benzodiazepine receptors. The Embo Journal. 9: 3261-7. PMID 2170110  1
1989 Gorman CM, Gies D, Schofield PR, Kado-Fong H, Malfroy B. Expression of enzymatically active enkephalinase (neutral endopeptidase) in mammalian cells. Journal of Cellular Biochemistry. 39: 277-84. PMID 2708459 DOI: 10.1002/jcb.240390307  1
1989 Shivers BD, Killisch I, Sprengel R, Sontheimer H, Köhler M, Schofield PR, Seeburg PH. Two novel GABAA receptor subunits exist in distinct neuronal subpopulations. Neuron. 3: 327-37. PMID 2561970 DOI: 10.1016/0896-6273(89)90257-2  1
1989 Ymer S, Schofield PR, Draguhn A, Werner P, Köhler M, Seeburg PH. GABAA receptor beta subunit heterogeneity: functional expression of cloned cDNAs. The Embo Journal. 8: 1665-70. PMID 2548852  1
1989 Pritchett DB, Sontheimer H, Shivers BD, Ymer S, Kettenmann H, Schofield PR, Seeburg PH. Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology. Nature. 338: 582-5. PMID 2538761 DOI: 10.1038/338582a0  1
1989 Sontheimer H, Becker CM, Pritchett DB, Schofield PR, Grenningloh G, Kettenmann H, Betz H, Seeburg PH. Functional chloride channels by mammalian cell expression of rat glycine receptor subunit. Neuron. 2: 1491-7. PMID 2483325 DOI: 10.1016/0896-6273(89)90195-5  1
1989 Ymer S, Schofield PR, Shivers BD, Pritchett DB, Lüddens H, Köhler M, Werner P, Sontheimer H, Kettenmann H, Seeburg PH. Molecular studies of the GABAA receptor. Journal of Protein Chemistry. 8: 352-5. PMID 2477011 DOI: 10.1007/BF01674275  1
1989 Schofield PR, Pritchett DB, Sontheimer H, Kettenmann H, Seeburg PH. Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits. Febs Letters. 244: 361-4. PMID 2465923 DOI: 10.1016/0014-5793(89)80563-0  1
1988 Malfroy B, Kuang WJ, Seeburg PH, Mason AJ, Schofield PR. Molecular cloning and amino acid sequence of human enkephalinase (neutral endopeptidase). Febs Letters. 229: 206-10. PMID 3162217 DOI: 10.1016/0014-5793(88)80828-7  1
1988 Barnard EA, Darlison MG, Fujita N, Glencorse TA, Levitan ES, Reale V, Schofield PR, Seeburg PH, Squire MD, Stephenson FA. Molecular biology of the GABAA receptor. Advances in Experimental Medicine and Biology. 236: 31-45. PMID 2853566  1
1988 Pritchett DB, Sontheimer H, Gorman CM, Kettenmann H, Seeburg PH, Schofield PR. Transient expression shows ligand gating and allosteric potentiation of GABAA receptor subunits. Science (New York, N.Y.). 242: 1306-8. PMID 2848320  1
1988 Levitan ES, Schofield PR, Burt DR, Rhee LM, Wisden W, Köhler M, Fujita N, Rodriguez HF, Stephenson A, Darlison MG. Structural and functional basis for GABAA receptor heterogeneity. Nature. 335: 76-9. PMID 2842688 DOI: 10.1038/335076a0  1
1987 Malfroy B, Schofield PR, Kuang WJ, Seeburg PH, Mason AJ, Henzel WJ. Molecular cloning and amino acid sequence of rat enkephalinase. Biochemical and Biophysical Research Communications. 144: 59-66. PMID 3555489 DOI: 10.1016/S0006-291X(87)80475-8  1
1987 Eipper BA, Park LP, Dickerson IM, Keutmann HT, Thiele EA, Rodriguez H, Schofield PR, Mains RE. Structure of the precursor to an enzyme mediating COOH-terminal amidation in peptide biosynthesis. Molecular Endocrinology (Baltimore, Md.). 1: 777-90. PMID 3153462 DOI: 10.1210/mend-1-11-777  1
1987 Braun T, Schofield PR, Shivers BD, Pritchett DB, Seeburg PH. A novel subtype of muscarinic receptor identified by homology screening. Biochemical and Biophysical Research Communications. 149: 125-32. PMID 3120722 DOI: 10.1016/0006-291X(87)91613-5  1
1987 Schofield PR, Darlison MG, Fujita N, Burt DR, Stephenson FA, Rodriguez H, Rhee LM, Ramachandran J, Reale V, Glencorse TA. Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family. Nature. 328: 221-7. PMID 3037384 DOI: 10.1038/328221a0  1
1987 Schofield PR, Rhee LM, Peralta EG. Primary structure of the human beta-adrenergic receptor gene. Nucleic Acids Research. 15: 3636. PMID 3033609 DOI: 10.1093/nar/15.8.3636  1
1987 Grenningloh G, Gundelfinger E, Schmitt B, Betz H, Darlison MG, Barnard EA, Schofield PR, Seeburg PH. Glycine vs GABA receptors. Nature. 330: 25-6. PMID 2823147 DOI: 10.1038/330025b0  1
1986 Djordjevic MA, Innes RW, Wijffelman CA, Schofield PR, Rolfe BG. Nodulation of specific legumes is controlled by several distinct loci in Rhizobium trifolii. Plant Molecular Biology. 6: 389-401. PMID 24307417 DOI: 10.1007/BF00027132  1
1985 Djordjevic MA, Schofield PR, Ridge RW, Morrison NA, Bassam BJ, Plazinski J, Watson JM, Rolfe BG. Rhizobium nodulation genes involved in root hair curling (Hac) are functionally conserved. Plant Molecular Biology. 4: 147-60. PMID 24310752 DOI: 10.1007/BF02418762  1
1984 Schofield PR, Ridge RW, Rolfe BG, Shine J, Watson JM. Host-specific nodulation is encoded on a 14kb DNA fragment in Rhizobium trifolii. Plant Molecular Biology. 3: 3-11. PMID 24310254 DOI: 10.1007/BF00023410  1
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