Year |
Citation |
Score |
2019 |
McLaughlin C, Clements J, Oprişoreanu AM, Sylantyev S. The role of tonic glycinergic conductance in cerebellar granule cells signalling and the effect of gain-of-function mutation. The Journal of Physiology. PMID 30875431 DOI: 10.1113/Jp277626 |
0.417 |
|
2012 |
Lester RAJ, Clements JD, Tong G, Westbrook GL, Jahr CE. The time course of NMDA receptor-mediated synaptic currents The Nmda Receptor. DOI: 10.1093/acprof:oso/9780192625021.003.0008 |
0.617 |
|
2005 |
Aubrey KR, Vandenberg RJ, Clements JD. Dynamics of forward and reverse transport by the glial glycine transporter, glyt1b. Biophysical Journal. 89: 1657-68. PMID 15951392 DOI: 10.1529/Biophysj.105.061572 |
0.407 |
|
2004 |
Kloda A, Clements JD, Lewis RJ, Adams DJ. Adenosine triphosphate acts as both a competitive antagonist and a positive allosteric modulator at recombinant N-methyl-D-aspartate receptors. Molecular Pharmacology. 65: 1386-96. PMID 15155832 DOI: 10.1124/Mol.65.6.1386 |
0.364 |
|
2004 |
Kampa BM, Clements J, Jonas P, Stuart GJ. Kinetics of Mg2+ unblock of NMDA receptors: implications for spike-timing dependent synaptic plasticity. The Journal of Physiology. 556: 337-45. PMID 14754998 DOI: 10.1113/Jphysiol.2003.058842 |
0.498 |
|
2003 |
Clements JD. Variance-mean analysis: a simple and reliable approach for investigating synaptic transmission and modulation. Journal of Neuroscience Methods. 130: 115-25. PMID 14667541 DOI: 10.1016/J.Jneumeth.2003.09.019 |
0.439 |
|
2003 |
Reid CA, Bekkers JM, Clements JD. Presynaptic Ca2+ channels: a functional patchwork. Trends in Neurosciences. 26: 683-7. PMID 14624853 DOI: 10.1016/J.Tins.2003.10.003 |
0.671 |
|
2002 |
Thoreson WB, Stella SL, Bryson EI, Clements J, Witkovsky P. D2-like dopamine receptors promote interactions between calcium and chloride channels that diminish rod synaptic transfer in the salamander retina. Visual Neuroscience. 19: 235-47. PMID 12392173 DOI: 10.1017/S0952523802192017 |
0.305 |
|
2002 |
Gentet LJ, Clements JD. Binding site stoichiometry and the effects of phosphorylation on human alpha1 homomeric glycine receptors. The Journal of Physiology. 544: 97-106. PMID 12356883 DOI: 10.1113/Jphysiol.2001.015321 |
0.382 |
|
2002 |
Kirischuk S, Clements JD, Grantyn R. Presynaptic and postsynaptic mechanisms underlie paired pulse depression at single GABAergic boutons in rat collicular cultures. The Journal of Physiology. 543: 99-116. PMID 12181284 DOI: 10.1113/Jphysiol.2002.021576 |
0.416 |
|
2002 |
Clements JD. Glycine receptor maturation: no experience required. The Journal of Physiology. 542: 665. PMID 12154167 DOI: 10.1113/Jphysiol.2002.025544 |
0.481 |
|
2001 |
Mansour M, Nagarajan N, Nehring RB, Clements JD, Rosenmund C. Heteromeric AMPA receptors assemble with a preferred subunit stoichiometry and spatial arrangement. Neuron. 32: 841-53. PMID 11738030 DOI: 10.1016/S0896-6273(01)00520-7 |
0.59 |
|
2000 |
Buck DP, Howitt SM, Clements JD. NMDA channel gating is influenced by a tryptophan residue in the M2 domain but calcium permeation is not altered. Biophysical Journal. 79: 2454-62. PMID 11053122 DOI: 10.1016/S0006-3495(00)76488-5 |
0.449 |
|
2000 |
Oleskevich S, Clements J, Walmsley B. Release probability modulates short-term plasticity at a rat giant terminal. The Journal of Physiology. 524: 513-23. PMID 10766930 DOI: 10.1111/J.1469-7793.2000.00513.X |
0.417 |
|
2000 |
Clements JD, Silver RA. Unveiling synaptic plasticity: a new graphical and analytical approach. Trends in Neurosciences. 23: 105-13. PMID 10675910 DOI: 10.1016/S0166-2236(99)01520-9 |
0.416 |
|
1999 |
Reid CA, Clements JD. Postsynaptic expression of long-term potentiation in the rat dentate gyrus demonstrated by variance-mean analysis. The Journal of Physiology. 518: 121-30. PMID 10373694 DOI: 10.1111/J.1469-7793.1999.0121R.X |
0.459 |
|
1999 |
Sah P, Clements JD. Photolytic manipulation of [Ca2+]i reveals slow kinetics of potassium channels underlying the afterhyperpolarization in hippocampal pyramidal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3657-64. PMID 10233997 DOI: 10.1523/Jneurosci.19-10-03657.1999 |
0.374 |
|
1999 |
Bekkers JM, Clements JD. Quantal amplitude and quantal variance of strontium-induced asynchronous EPSCs in rat dentate granule neurons. The Journal of Physiology. 516: 227-48. PMID 10066937 DOI: 10.1111/J.1469-7793.1999.227Aa.X |
0.672 |
|
1998 |
Reid CA, Bekkers JM, Clements JD. N- and P/Q-type Ca2+ channels mediate transmitter release with a similar cooperativity at rat hippocampal autapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2849-55. PMID 9526002 DOI: 10.1523/Jneurosci.18-08-02849.1998 |
0.663 |
|
1998 |
Clements JD, Feltz A, Sahara Y, Westbrook GL. Activation kinetics of AMPA receptor channels reveal the number of functional agonist binding sites. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 119-27. PMID 9412492 DOI: 10.1523/Jneurosci.18-01-00119.1998 |
0.623 |
|
1997 |
Clements JD, Bekkers JM. Detection of spontaneous synaptic events with an optimally scaled template. Biophysical Journal. 73: 220-9. PMID 9199786 DOI: 10.1016/S0006-3495(97)78062-7 |
0.622 |
|
1997 |
Reid CA, Clements JD, Bekkers JM. Nonuniform distribution of Ca2+ channel subtypes on presynaptic terminals of excitatory synapses in hippocampal cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2738-45. PMID 9092595 DOI: 10.1523/Jneurosci.17-08-02738.1997 |
0.692 |
|
1996 |
Clements JD. Transmitter timecourse in the synaptic cleft: its role in central synaptic function. Trends in Neurosciences. 19: 163-71. PMID 8723198 DOI: 10.1016/S0166-2236(96)10024-2 |
0.488 |
|
1994 |
Clements JD, Westbrook GL. Kinetics of AP5 dissociation from NMDA receptors: evidence for two identical cooperative binding sites. Journal of Neurophysiology. 71: 2566-9. PMID 7931537 DOI: 10.1152/Jn.1994.71.6.2566 |
0.596 |
|
1993 |
Rosenmund C, Clements JD, Westbrook GL. Nonuniform probability of glutamate release at a hippocampal synapse. Science (New York, N.Y.). 262: 754-7. PMID 7901909 DOI: 10.1126/Science.7901909 |
0.719 |
|
1993 |
Sahara Y, Clements JD, Feltz A, Westbrook GL. 316 How many agonist binding sites do AMPA/kainate receptor channels have? Neuroscience Research Supplements. 18: S42. DOI: 10.1016/S0921-8696(05)80786-8 |
0.616 |
|
1992 |
Clements JD, Lester RA, Tong G, Jahr CE, Westbrook GL. The time course of glutamate in the synaptic cleft. Science (New York, N.Y.). 258: 1498-501. PMID 1359647 DOI: 10.1126/Science.1359647 |
0.659 |
|
1991 |
Clements JD, Westbrook GL. Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-D-aspartate receptor. Neuron. 7: 605-13. PMID 1681832 DOI: 10.1016/0896-6273(91)90373-8 |
0.624 |
|
1991 |
Clements J. Quantal synaptic transmission? Nature. 353: 396. PMID 1654524 DOI: 10.1038/353396A0 |
0.405 |
|
1990 |
Clements JD. A statistical test for demonstrating a presynaptic site of action for a modulator of synaptic amplitude. Journal of Neuroscience Methods. 31: 75-88. PMID 2308384 DOI: 10.1016/0165-0270(90)90012-5 |
0.439 |
|
1990 |
Forsythe ID, Clements JD. Presynaptic glutamate receptors depress excitatory monosynaptic transmission between mouse hippocampal neurones. The Journal of Physiology. 429: 1-16. PMID 2177502 DOI: 10.1113/Jphysiol.1990.Sp018240 |
0.607 |
|
1990 |
Lester RA, Clements JD, Westbrook GL, Jahr CE. Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents. Nature. 346: 565-7. PMID 1974037 DOI: 10.1038/346565A0 |
0.678 |
|
1989 |
Clements JD, Redman SJ. Cable properties of cat spinal motoneurones measured by combining voltage clamp, current clamp and intracellular staining. The Journal of Physiology. 409: 63-87. PMID 2585300 DOI: 10.1113/Jphysiol.1989.Sp017485 |
0.315 |
|
1989 |
Mayer ML, Vyklicky L, Clements J. Regulation of NMDA receptor desensitization in mouse hippocampal neurons by glycine. Nature. 338: 425-7. PMID 2538755 DOI: 10.1038/338425A0 |
0.355 |
|
1987 |
Clements JD, Forsythe ID, Redman SJ. Presynaptic inhibition of synaptic potentials evoked in cat spinal motoneurones by impulses in single group Ia axons. The Journal of Physiology. 383: 153-69. PMID 2821234 DOI: 10.1113/Jphysiol.1987.Sp016402 |
0.574 |
|
1986 |
Clements JD, Nelson PG, Redman SJ. Intracellular tetraethylammonium ions enhance group Ia excitatory post-synaptic potentials evoked in cat motoneurones. The Journal of Physiology. 377: 267-82. PMID 2432243 DOI: 10.1113/jphysiol.1986.sp016186 |
0.476 |
|
Low-probability matches (unlikely to be authored by this person) |
1993 |
Oleskevich S, Clements JD, Williams JT. Opioid-glutamate interactions in rat locus coeruleus neurons. Journal of Neurophysiology. 70: 931-7. PMID 7693886 DOI: 10.1152/Jn.1993.70.3.931 |
0.298 |
|
2000 |
Gentet LJ, Stuart GJ, Clements JD. Direct measurement of specific membrane capacitance in neurons. Biophysical Journal. 79: 314-20. PMID 10866957 DOI: 10.1016/S0006-3495(00)76293-X |
0.297 |
|
2002 |
Clements JD, Martin RE. Identification of novel membrane proteins by searching for patterns in hydropathy profiles. European Journal of Biochemistry / Febs. 269: 2101-7. PMID 11985587 DOI: 10.1046/J.1432-1033.2002.02859.X |
0.296 |
|
1997 |
Oleskevich S, Clements JD, Srinivasan MV. Long-term synaptic plasticity in the honeybee. Journal of Neurophysiology. 78: 528-32. PMID 9242301 DOI: 10.1152/jn.1997.78.1.528 |
0.248 |
|
2005 |
Martin RE, Henry RI, Abbey JL, Clements JD, Kirk K. The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum. Genome Biology. 6: R26. PMID 15774027 DOI: 10.1186/Gb-2005-6-3-R26 |
0.237 |
|
2004 |
Han NL, Clements JD, Lynch JW. Comparison of taurine- and glycine-induced conformational changes in the M2-M3 domain of the glycine receptor. The Journal of Biological Chemistry. 279: 19559-65. PMID 14981077 DOI: 10.1074/Jbc.M400548200 |
0.226 |
|
1996 |
Tierney ML, Birnir B, Pillai NP, Clements JD, Howitt SM, Cox GB, Gage PW. Effects of mutating leucine to threonine in the M2 segment of alpha1 and beta1 subunits of GABAA alpha1beta1 receptors. The Journal of Membrane Biology. 154: 11-21. PMID 8881023 DOI: 10.1007/s002329900128 |
0.182 |
|
1997 |
Guidry JJ, Cárdenas L, Cheng E, Clements JD. Role of receptor binding in toxicity, immunogenicity, and adjuvanticity of Escherichia coli heat-labile enterotoxin. Infection and Immunity. 65: 4943-50. PMID 9393780 DOI: 10.1128/iai.65.12.4943-4950.1997 |
0.162 |
|
2009 |
Clements JD, Jamali F. Norepinephrine transporter is involved in down-regulation of beta1-adrenergic receptors caused by adjuvant arthritis. Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society For Pharmaceutical Sciences, Sociã©Tã© Canadienne Des Sciences Pharmaceutiques. 12: 337-45. PMID 20067708 |
0.144 |
|
2012 |
Norton EB, Lawson LB, Mahdi Z, Freytag LC, Clements JD. The A subunit of Escherichia coli heat-labile enterotoxin functions as a mucosal adjuvant and promotes IgG2a, IgA, and Th17 responses to vaccine antigens. Infection and Immunity. 80: 2426-35. PMID 22526674 DOI: 10.1128/Iai.00181-12 |
0.123 |
|
2015 |
Norton EB, Branco LM, Clements JD. Evaluating the A-Subunit of the Heat-Labile Toxin (LT) As an Immunogen and a Protective Antigen Against Enterotoxigenic Escherichia coli (ETEC). Plos One. 10: e0136302. PMID 26305793 DOI: 10.1371/journal.pone.0136302 |
0.108 |
|
1999 |
Cárdenas-Freytag L, Cheng E, Mayeux P, Domer JE, Clements JD. Effectiveness of a vaccine composed of heat-killed Candida albicans and a novel mucosal adjuvant, LT(R192G), against systemic candidiasis. Infection and Immunity. 67: 826-33. PMID 9916097 DOI: 10.1128/IAI.67.2.826-833.1999 |
0.106 |
|
2001 |
McCluskie MJ, Weeratna RD, Clements JD, Davis HL. Mucosal immunization of mice using CpG DNA and/or mutants of the heat-labile enterotoxin of Escherichia coli as adjuvants. Vaccine. 19: 3759-68. PMID 11395211 DOI: 10.1016/S0264-410X(01)00088-3 |
0.104 |
|
2015 |
Chen X, Choudhari SP, Martinez-Becerra FJ, Kim JH, Dickenson NE, Toth RT, Joshi SB, Greenwood JC, Clements JD, Picking WD, Middaugh CR, Picking WL. Impact of detergent on biophysical properties and immune response of the IpaDB fusion protein, a candidate subunit vaccine against Shigella species. Infection and Immunity. 83: 292-9. PMID 25368115 DOI: 10.1128/Iai.02457-14 |
0.103 |
|
2010 |
Basset C, Thiam F, Martino CD, Holton J, Clements JD, Kohli E. Cholera-like enterotoxins and Regulatory T cells. Toxins. 2: 1774-95. PMID 22069660 DOI: 10.3390/toxins2071774 |
0.102 |
|
1999 |
Cheng E, Cárdenas-Freytag L, Clements JD. The role of cAMP in mucosal adjuvanticity of Escherichia coli heat-labile enterotoxin (LT). Vaccine. 18: 38-49. PMID 10501233 DOI: 10.1016/S0264-410X(99)00168-1 |
0.1 |
|
1983 |
Klipstein FA, Engert RF, Clements JD, Houghten RA. Vaccine for enterotoxigenic Escherichia coli based on synthetic heat-stable toxin crossed-linked to the B subunit of heat-labile toxin. The Journal of Infectious Diseases. 147: 318-26. PMID 6338132 DOI: 10.1093/INFDIS/147.2.318 |
0.099 |
|
1979 |
Clements JD, Finkelstein RA. Isolation and characterization of homogeneous heat-labile enterotoxins with high specific activity from Escherichia coli cultures. Infection and Immunity. 24: 760-9. PMID 89088 DOI: 10.1128/iai.24.3.760-769.1979 |
0.095 |
|
2013 |
Novotny LA, Clements JD, Bakaletz LO. Kinetic analysis and evaluation of the mechanisms involved in the resolution of experimental nontypeable Haemophilus influenzae-induced otitis media after transcutaneous immunization. Vaccine. 31: 3417-26. PMID 23092856 DOI: 10.1016/j.vaccine.2012.10.033 |
0.094 |
|
2007 |
Clements JD, Jamali F. Pravastatin reverses the down-regulating effect of inflammation on beta-adrenergic receptors: a disease-drug interaction between inflammation, pravastatin, and propranolol. Vascular Pharmacology. 46: 52-9. PMID 16949884 DOI: 10.1016/j.vph.2006.06.009 |
0.094 |
|
1981 |
Gill DM, Clements JD, Robertson DC, Finkelstein RA. Subunit number and arrangement in Escherichia coli heat-labile enterotoxin. Infection and Immunity. 33: 677-82. PMID 7026442 |
0.09 |
|
2005 |
Freytag LC, Clements JD. Mucosal adjuvants. Vaccine. 23: 1804-13. PMID 15734046 DOI: 10.1016/j.vaccine.2004.11.010 |
0.09 |
|
2002 |
Choi AH, McNeal MM, Flint JA, Basu M, Lycke NY, Clements JD, Bean JA, Davis HL, McCluskie MJ, VanCott JL, Ward RL. The level of protection against rotavirus shedding in mice following immunization with a chimeric VP6 protein is dependent on the route and the coadministered adjuvant. Vaccine. 20: 1733-40. PMID 11906760 DOI: 10.1016/S0264-410X(02)00043-9 |
0.089 |
|
2003 |
Zhang P, Yang QB, Marciani DJ, Martin M, Clements JD, Michalek SM, Katz J. Effectiveness of the quillaja saponin semi-synthetic analog GPI-0100 in potentiating mucosal and systemic responses to recombinant HagB from Porphyromonas gingivalis. Vaccine. 21: 4459-71. PMID 14505929 DOI: 10.1016/S0264-410X(03)00438-9 |
0.087 |
|
1980 |
Clements JD, Yancey RJ, Finkelstein RA. Properties of homogeneous heat-labile enterotoxin from Escherichia coli. Infection and Immunity. 29: 91-7. PMID 6156914 DOI: 10.1128/iai.29.1.91-97.1980 |
0.086 |
|
2001 |
Bowman CC, Clements JD. Differential biological and adjuvant activities of cholera toxin and Escherichia coli heat-labile enterotoxin hybrids. Infection and Immunity. 69: 1528-35. PMID 11179323 DOI: 10.1128/IAI.69.3.1528-1535.2001 |
0.086 |
|
2020 |
Kiefer MC, Motyka NI, Clements JD, Bitoun JP. Enterotoxigenic Escherichia coli Heat-Stable Toxin Increases the Rate of Zinc Release from Metallothionein and Is a Zinc- and Iron-Binding Peptide. Msphere. 5. PMID 32238569 DOI: 10.1128/mSphere.00146-20 |
0.085 |
|
2011 |
Norton EB, Lawson LB, Freytag LC, Clements JD. Characterization of a mutant Escherichia coli heat-labile toxin, LT(R192G/L211A), as a safe and effective oral adjuvant. Clinical and Vaccine Immunology : Cvi. 18: 546-51. PMID 21288994 DOI: 10.1128/Cvi.00538-10 |
0.084 |
|
1991 |
Clements JD, Buzy JM. Automated image analysis for counting unstained cultured neurones. Journal of Neuroscience Methods. 36: 1-8. PMID 1712054 DOI: 10.1016/0165-0270(91)90131-I |
0.083 |
|
1995 |
Dickinson BL, Clements JD. Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity. Infection and Immunity. 63: 1617-23. PMID 7729864 DOI: 10.1128/iai.63.5.1617-1623.1995 |
0.082 |
|
2005 |
Zhang P, Yang QB, Balkovetz DF, Lewis JP, Clements JD, Michalek SM, Katz J. Effectiveness of the B subunit of cholera toxin in potentiating immune responses to the recombinant hemagglutinin/adhesin domain of the gingipain Kgp from Porphyromonas gingivalis. Vaccine. 23: 4734-44. PMID 15955601 DOI: 10.1016/J.Vaccine.2005.05.004 |
0.08 |
|
1984 |
Klipstein FA, Engert RF, Clements JD, Houghten RA. Differences in cross-protection in rats immunized with the B subunits of cholera toxin and Escherichia coli heat-labile toxin. Infection and Immunity. 43: 811-6. PMID 6365784 DOI: 10.1128/iai.43.3.811-816.1984 |
0.079 |
|
2009 |
Bogaerts S, Clements JD, Sullivan JM, Oleskevich S. Automated threshold detection for auditory brainstem responses: comparison with visual estimation in a stem cell transplantation study. Bmc Neuroscience. 10: 104. PMID 19706195 DOI: 10.1186/1471-2202-10-104 |
0.079 |
|
1995 |
Bost KL, Clements JD. In vivo induction of interleukin-12 mRNA expression after oral immunization with Salmonella dublin or the B subunit of Escherichia coli heat-labile enterotoxin. Infection and Immunity. 63: 1076-83. PMID 7868230 DOI: 10.1128/Iai.63.3.1076-1083.1995 |
0.079 |
|
2019 |
Maciel M, Bauer D, Baudier RL, Bitoun J, Clements JD, Poole ST, Smith MA, Kaminski RW, Savarino SJ, Norton EB. Intradermal or sublingual delivery and heat-labile enterotoxin (LT) proteins shape immunologic outcomes to CFA/I fimbriae-derived subunit antigen vaccine against enterotoxigenic . Infection and Immunity. PMID 31427449 DOI: 10.1128/IAI.00460-19 |
0.078 |
|
2003 |
Choi AH, McNeal MM, Basu M, Bean JA, VanCott JL, Clements JD, Ward RL. Functional mapping of protective epitopes within the rotavirus VP6 protein in mice belonging to different haplotypes. Vaccine. 21: 761-7. PMID 12531356 DOI: 10.1016/S0264-410X(02)00595-9 |
0.077 |
|
2002 |
Cárdenas-Freytag L, Steele C, Wormley FL, Cheng E, Clements JD, Fidel PL. Partial protection against experimental vaginal candidiasis after mucosal vaccination with heat-killed Candida albicans and the mucosal adjuvant LT(R192G). Medical Mycology. 40: 291-9. PMID 12146759 DOI: 10.1080/Mmy.40.3.291.299 |
0.077 |
|
2011 |
Sanaee F, Clements JD, Waugh AW, Fedorak RN, Lewanczuk R, Jamali F. Drug-disease interaction: Crohn's disease elevates verapamil plasma concentrations but reduces response to the drug proportional to disease activity. British Journal of Clinical Pharmacology. 72: 787-97. PMID 21592185 DOI: 10.1111/j.1365-2125.2011.04019.x |
0.076 |
|
2002 |
Choi AH, McNeal MM, Basu M, Flint JA, Stone SC, Clements JD, Bean JA, Poe SA, VanCott JL, Ward RL. Intranasal or oral immunization of inbred and outbred mice with murine or human rotavirus VP6 proteins protects against viral shedding after challenge with murine rotaviruses. Vaccine. 20: 3310-21. PMID 12213401 DOI: 10.1016/S0264-410X(02)00315-8 |
0.075 |
|
1978 |
Clements JD, Finkelstein RA. Immunological cross-reactivity between a heat-labile enterotoxin(s) of Escherichia coli and subunits of Vibrio cholerae enterotoxin. Infection and Immunity. 21: 1036-9. PMID 361573 DOI: 10.1128/iai.21.3.1036-1039.1978 |
0.074 |
|
2021 |
Motyka NI, Stewart SR, Hollifield IE, Kyllo TR, Mansfield JA, Norton EB, Clements JD, Bitoun JP. Elevated Extracellular cGMP Produced after Exposure to Enterotoxigenic (ETEC) Heat-Stable Toxin (ST) Induces Epithelial IL-33 Release and Alters Intestinal Immunity. Infection and Immunity. PMID 33431701 DOI: 10.1128/IAI.00707-20 |
0.073 |
|
1978 |
Clements JD, Finkelstein RA. Demonstration of shared and unique immunological determinants in enterotoxins from Vibrio cholerae and Escherichia coli. Infection and Immunity. 22: 709-13. PMID 83301 DOI: 10.1128/iai.22.3.709-713.1978 |
0.073 |
|
1990 |
Clements JD. Construction of a nontoxic fusion peptide for immunization against Escherichia coli strains that produce heat-labile and heat-stable enterotoxins. Infection and Immunity. 58: 1159-66. PMID 2182535 DOI: 10.1128/iai.58.5.1159-1166.1990 |
0.072 |
|
1986 |
Clements JD, Lyon FL, Lowe KL, Farrand AL, el-Morshidy S. Oral immunization of mice with attenuated Salmonella enteritidis containing a recombinant plasmid which codes for production of the B subunit of heat-labile Escherichia coli enterotoxin. Infection and Immunity. 53: 685-92. PMID 3527989 DOI: 10.1128/iai.53.3.685-692.1986 |
0.072 |
|
2010 |
Lu YJ, Yadav P, Clements JD, Forte S, Srivastava A, Thompson CM, Seid R, Look J, Alderson M, Tate A, Maisonneuve JF, Robertson G, Anderson PW, Malley R. Options for inactivation, adjuvant, and route of topical administration of a killed, unencapsulated pneumococcal whole-cell vaccine. Clinical and Vaccine Immunology : Cvi. 17: 1005-12. PMID 20427625 DOI: 10.1128/CVI.00036-10 |
0.072 |
|
2001 |
Guerrero RA, Ball JM, Krater SS, Pacheco SE, Clements JD, Estes MK. Recombinant Norwalk virus-like particles administered intranasally to mice induce systemic and mucosal (fecal and vaginal) immune responses. Journal of Virology. 75: 9713-22. PMID 11559804 DOI: 10.1128/Jvi.75.20.9713-9722.2001 |
0.072 |
|
1990 |
Clements JD, Cárdenas L. Vaccines against enterotoxigenic bacterial pathogens based on hybrid Salmonella that express heterologous antigens. Research in Microbiology. 141: 981-93. PMID 2101489 DOI: 10.1016/0923-2508(90)90138-G |
0.071 |
|
1988 |
Clements JD, Hartzog NM, Lyon FL. Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens. Vaccine. 6: 269-77. PMID 3048010 DOI: 10.1016/0264-410X(88)90223-X |
0.071 |
|
2012 |
Martinez-Becerra FJ, Kissmann JM, Diaz-McNair J, Choudhari SP, Quick AM, Mellado-Sanchez G, Clements JD, Pasetti MF, Picking WL. Broadly protective Shigella vaccine based on type III secretion apparatus proteins. Infection and Immunity. 80: 1222-31. PMID 22202122 DOI: 10.1128/Iai.06174-11 |
0.07 |
|
1985 |
Clements JD, Lowe KL, Bonham L, el-Morshidy S. Intracellular distribution of heat-labile enterotoxin in a clinical isolate of Escherichia coli. Infection and Immunity. 50: 317-9. PMID 3899935 DOI: 10.1128/iai.50.1.317-319.1985 |
0.07 |
|
2004 |
Choi AH, Basu M, McNeal MM, Bean JA, Clements JD, Ward RL. Intranasal administration of an Escherichia coli-expressed codon-optimized rotavirus VP6 protein induces protection in mice. Protein Expression and Purification. 38: 205-16. PMID 15555936 DOI: 10.1016/j.pep.2004.08.009 |
0.069 |
|
2014 |
Read LT, Hahn RW, Thompson CC, Bauer DL, Norton EB, Clements JD. Simultaneous exposure to Escherichia coli heat-labile and heat-stable enterotoxins increases fluid secretion and alters cyclic nucleotide and cytokine production by intestinal epithelial cells. Infection and Immunity. 82: 5308-16. PMID 25287923 DOI: 10.1128/IAI.02496-14 |
0.069 |
|
2006 |
Belyakov IM, Kuznetsov VA, Kelsall B, Klinman D, Moniuszko M, Lemon M, Markham PD, Pal R, Clements JD, Lewis MG, Strober W, Franchini G, Berzofsky JA. Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa. Blood. 107: 3258-64. PMID 16373659 DOI: 10.1182/Blood-2005-11-4374 |
0.067 |
|
1992 |
Cárdenas L, Clements JD. Oral immunization using live attenuated Salmonella spp. as carriers of foreign antigens. Clinical Microbiology Reviews. 5: 328-42. PMID 1498769 DOI: 10.1128/CMR.5.3.328 |
0.066 |
|
1999 |
Choi AH, Basu M, McNeal MM, Clements JD, Ward RL. Antibody-independent protection against rotavirus infection of mice stimulated by intranasal immunization with chimeric VP4 or VP6 protein. Journal of Virology. 73: 7574-81. PMID 10438847 DOI: 10.1128/JVI.73.9.7574-7581.1999 |
0.066 |
|
1983 |
Klipstein FA, Engert RF, Clements JD, Houghten RA. Protection against human and porcine enterotoxigenic strains of Escherichia coli in rats immunized with a cross-linked toxoid vaccine. Infection and Immunity. 40: 924-9. PMID 6343245 DOI: 10.1128/iai.40.3.924-929.1983 |
0.066 |
|
2017 |
Novotny LA, Clements JD, Goodman SD, Bakaletz LO. Transcutaneous immunization with a bandaid prevents experimental otitis media in a polymicrobial model. Clinical and Vaccine Immunology : Cvi. PMID 28381402 DOI: 10.1128/CVI.00563-16 |
0.066 |
|
1983 |
Clements JD, Flint DC, Engert RF, Klipstein FA. Cloning and molecular characterization of the B subunit of Escherichia coli heat-labile enterotoxin. Infection and Immunity. 40: 653-8. PMID 6341243 DOI: 10.1128/iai.40.2.653-658.1983 |
0.065 |
|
1997 |
Toebe CS, Clements JD, Cardenas L, Jennings GJ, Wiser MF. Evaluation of immunogenicity of an oral Salmonella vaccine expressing recombinant Plasmodium berghei merozoite surface protein-1. The American Journal of Tropical Medicine and Hygiene. 56: 192-9. PMID 9080880 DOI: 10.4269/Ajtmh.1997.56.192 |
0.064 |
|
1986 |
Stanton BF, Clemens JD, Clements JD. Soiled saris: a vector of disease transmission? Transactions of the Royal Society of Tropical Medicine and Hygiene. 80: 485-8. PMID 3798547 DOI: 10.1016/0035-9203(86)90353-6 |
0.064 |
|
2014 |
White JA, Blum JS, Hosken NA, Marshak JO, Duncan L, Zhu C, Norton EB, Clements JD, Koelle DM, Chen D, Weldon WC, Oberste MS, Lal M. Serum and mucosal antibody responses to inactivated polio vaccine after sublingual immunization using a thermoresponsive gel delivery system. Human Vaccines & Immunotherapeutics. 10: 3611-21. PMID 25483682 DOI: 10.4161/Hv.32253 |
0.064 |
|
2000 |
Choi AH, Basu M, McNeal MM, Flint J, VanCott JL, Clements JD, Ward RL. Functional mapping of protective domains and epitopes in the rotavirus VP6 protein. Journal of Virology. 74: 11574-80. PMID 11090155 DOI: 10.1128/JVI.74.24.11574-11580.2000 |
0.064 |
|
1982 |
Klipstein FA, Engert RF, Clements JD. Development of a vaccine of cross-linked heat-stable and heat-labile enterotoxins that protects against Escherichia coli producing either enterotoxin. Infection and Immunity. 37: 550-7. PMID 6749682 DOI: 10.1128/iai.37.2.550-557.1982 |
0.064 |
|
2005 |
Glynn A, Freytag LC, Clements JD. Effect of homologous and heterologous prime-boost on the immune response to recombinant plague antigens. Vaccine. 23: 1957-65. PMID 15734068 DOI: 10.1016/J.Vaccine.2004.10.025 |
0.064 |
|
1997 |
Bost KL, Clements JD. Intracellular Salmonella dublin induces substantial secretion of the 40-kilodalton subunit of interleukin-12 (IL-12) but minimal secretion of IL-12 as a 70-kilodalton protein in murine macrophages. Infection and Immunity. 65: 3186-92. PMID 9234773 DOI: 10.1128/Iai.65.8.3186-3192.1997 |
0.063 |
|
2010 |
Norton EB, Clements JD, Voss TG, Cárdenas-Freytag L. Prophylactic administration of bacterially derived immunomodulators improves the outcome of influenza virus infection in a murine model. Journal of Virology. 84: 2983-95. PMID 20053748 DOI: 10.1128/Jvi.01805-09 |
0.063 |
|
1994 |
Szu SC, Taylor DN, Trofa AC, Clements JD, Shiloach J, Sadoff JC, Bryla DA, Robbins JB. Laboratory and preliminary clinical characterization of Vi capsular polysaccharide-protein conjugate vaccines. Infection and Immunity. 62: 4440-4. PMID 7927707 DOI: 10.1128/IAI.62.10.4440-4444.1994 |
0.063 |
|
1976 |
Nelson ET, Clements JD, Finkelstein RA. Vibrio cholerae adherence and colonization in experimental cholera: electron microscopic studies. Infection and Immunity. 14: 527-47. PMID 971962 DOI: 10.1128/iai.14.2.527-547.1976 |
0.063 |
|
2012 |
Tarique AA, Kalsy A, Arifuzzaman M, Rollins SM, Charles RC, Leung DT, Harris JB, Larocque RC, Sheikh A, Bhuiyan MS, Saksena R, Clements JD, Calderwood SB, Qadri F, Kovác P, et al. Transcutaneous immunization with a Vibrio cholerae O1 Ogawa synthetic hexasaccharide conjugate following oral whole-cell cholera vaccination boosts vibriocidal responses and induces protective immunity in mice. Clinical and Vaccine Immunology : Cvi. 19: 594-602. PMID 22357651 DOI: 10.1128/Cvi.05689-11 |
0.062 |
|
1984 |
Clements JD, El-Morshidy S. Construction of a potential live oral bivalent vaccine for typhoid fever and cholera-Escherichia coli-related diarrheas. Infection and Immunity. 46: 564-9. PMID 6389350 DOI: 10.1128/iai.46.2.564-569.1984 |
0.061 |
|
1996 |
Takahashi I, Kiyono H, Jackson RJ, Fujihashi K, Staats HF, Hamada S, Clements JD, Bost KL, McGhee JR. Epitope maps of the Escherichia coli heat-labile toxin B subunit for development of a synthetic oral vaccine. Infection and Immunity. 64: 1290-8. PMID 8606092 DOI: 10.1128/Iai.64.4.1290-1298.1996 |
0.061 |
|
1994 |
Cárdenas L, Dasgupta U, Clements JD. Influence of strain viability and antigen dose on the use of attenuated mutants of Salmonella as vaccine carriers. Vaccine. 12: 833-40. PMID 7975861 DOI: 10.1016/0264-410X(94)90293-3 |
0.06 |
|
2013 |
Martinez-Becerra FJ, Chen X, Dickenson NE, Choudhari SP, Harrison K, Clements JD, Picking WD, Van De Verg LL, Walker RI, Picking WL. Characterization of a novel fusion protein from IpaB and IpaD of Shigella spp. and its potential as a pan-Shigella vaccine. Infection and Immunity. 81: 4470-7. PMID 24060976 DOI: 10.1128/Iai.00859-13 |
0.059 |
|
1993 |
Rollwagen FM, Pacheco ND, Clements JD, Pavlovskis O, Rollins DM, Walker RI. Killed Campylobacter elicits immune response and protection when administered with an oral adjuvant. Vaccine. 11: 1316-20. PMID 8296484 DOI: 10.1016/0264-410X(93)90101-3 |
0.059 |
|
1998 |
Tacket CO, Mason HS, Losonsky G, Clements JD, Levine MM, Arntzen CJ. Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato. Nature Medicine. 4: 607-9. PMID 9585236 DOI: 10.1038/Nm0598-607 |
0.059 |
|
2000 |
Guillobel HC, Carinhanha JI, Cárdenas L, Clements JD, de Almeida DF, Ferreira LC. Adjuvant activity of a nontoxic mutant of Escherichia coli heat-labile enterotoxin on systemic and mucosal immune responses elicited against a heterologous antigen carried by a live Salmonella enterica serovar Typhimurium vaccine strain. Infection and Immunity. 68: 4349-53. PMID 10858258 DOI: 10.1128/IAI.68.7.4349-4353.2000 |
0.058 |
|
2009 |
Quan FS, Yoo DG, Song JM, Clements JD, Compans RW, Kang SM. Kinetics of immune responses to influenza virus-like particles and dose-dependence of protection with a single vaccination. Journal of Virology. 83: 4489-97. PMID 19211762 DOI: 10.1128/Jvi.02035-08 |
0.058 |
|
1986 |
Alving CR, Richards RL, Moss J, Alving LI, Clements JD, Shiba T, Kotani S, Wirtz RA, Hockmeyer WT. Effectiveness of liposomes as potential carriers of vaccines: applications to cholera toxin and human malaria sporozoite antigen. Vaccine. 4: 166-72. PMID 3532603 DOI: 10.1016/0264-410X(86)90005-8 |
0.057 |
|
2010 |
Tribble DR, Baqar S, Scott DA, Oplinger ML, Trespalacios F, Rollins D, Walker RI, Clements JD, Walz S, Gibbs P, Burg EF, Moran AP, Applebee L, Bourgeois AL. Assessment of the duration of protection in Campylobacter jejuni experimental infection in humans. Infection and Immunity. 78: 1750-9. PMID 20086085 DOI: 10.1128/IAI.01021-09 |
0.057 |
|
2007 |
Smiley KL, McNeal MM, Basu M, Choi AH, Clements JD, Ward RL. Association of gamma interferon and interleukin-17 production in intestinal CD4+ T cells with protection against rotavirus shedding in mice intranasally immunized with VP6 and the adjuvant LT(R192G). Journal of Virology. 81: 3740-8. PMID 17251301 DOI: 10.1128/JVI.01877-06 |
0.057 |
|
2001 |
Morris CB, Thanawastien A, Sullivan DE, Clements JD. Identification of a peptide capable of inducing an HIV-1 Tat-specific CTL response. Vaccine. 20: 12-5. PMID 11567739 DOI: 10.1016/S0264-410X(01)00271-7 |
0.057 |
|
1993 |
Cárdenas L, Clements JD. Development of mucosal protection against the heat-stable enterotoxin (ST) of Escherichia coli by oral immunization with a genetic fusion delivered by a bacterial vector. Infection and Immunity. 61: 4629-36. PMID 8406860 DOI: 10.1128/iai.61.11.4629-4636.1993 |
0.057 |
|
2019 |
Jones AT, Shen X, Walter KL, LaBranche CC, Wyatt LS, Tomaras GD, Montefiori DC, Moss B, Barouch DH, Clements JD, Kozlowski PA, Varadarajan R, Amara RR. HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge. Nature Communications. 10: 798. PMID 30778066 DOI: 10.1038/S41467-019-08739-4 |
0.057 |
|
2012 |
Leach S, Clements JD, Kaim J, Lundgren A. The adjuvant double mutant Escherichia coli heat labile toxin enhances IL-17A production in human T cells specific for bacterial vaccine antigens. Plos One. 7: e51718. PMID 23284753 DOI: 10.1371/journal.pone.0051718 |
0.056 |
|
2014 |
Ruan X, Robertson DC, Nataro JP, Clements JD, Zhang W. Characterization of heat-stable (STa) toxoids of enterotoxigenic Escherichia coli fused to double mutant heat-labile toxin peptide in inducing neutralizing Anti-STa antibodies. Infection and Immunity. 82: 1823-32. PMID 24549325 DOI: 10.1128/Iai.01394-13 |
0.056 |
|
2007 |
Uddowla S, Freytag LC, Clements JD. Effect of adjuvants and route of immunizations on the immune response to recombinant plague antigens. Vaccine. 25: 7984-93. PMID 17933440 DOI: 10.1016/J.Vaccine.2007.09.030 |
0.055 |
|
2006 |
VanCott JL, Prada AE, McNeal MM, Stone SC, Basu M, Huffer B, Smiley KL, Shao M, Bean JA, Clements JD, Choi AH, Ward RL. Mice develop effective but delayed protective immune responses when immunized as neonates either intranasally with nonliving VP6/LT(R192G) or orally with live rhesus rotavirus vaccine candidates. Journal of Virology. 80: 4949-61. PMID 16641286 DOI: 10.1128/JVI.80.10.4949-4961.2006 |
0.055 |
|
1996 |
Chong C, Bost KL, Clements JD. Differential production of interleukin-12 mRNA by murine macrophages in response to viable or killed Salmonella spp. Infection and Immunity. 64: 1154-60. PMID 8606072 DOI: 10.1128/Iai.64.4.1154-1160.1996 |
0.055 |
|
1995 |
Haq TA, Mason HS, Clements JD, Arntzen CJ. Oral immunization with a recombinant bacterial antigen produced in transgenic plants. Science (New York, N.Y.). 268: 714-6. PMID 7732379 DOI: 10.1126/Science.7732379 |
0.055 |
|
1982 |
Klipstein FA, Engert RF, Clements JD. Arousal of mucosal secretory immunoglobulin A antitoxin in rats immunized with Escherichia coli heat-labile enterotoxin. Infection and Immunity. 37: 1086-92. PMID 7129629 DOI: 10.1128/iai.37.3.1086-1092.1982 |
0.054 |
|
2012 |
Lawson LB, Clements JD, Freytag LC. Mucosal immune responses induced by transcutaneous vaccines. Current Topics in Microbiology and Immunology. 354: 19-37. PMID 22435116 DOI: 10.1007/82_2010_113 |
0.054 |
|
2018 |
Clements JD, Norton EB. The Mucosal Vaccine Adjuvant LT(R192G/L211A) or dmLT. Msphere. 3. PMID 30045966 DOI: 10.1128/mSphere.00215-18 |
0.054 |
|
2020 |
Chaudhary O, Wang L, Bose D, Narayan V, Yeh MT, Carville A, Clements J, Andino R, Kozlowski PA, Aldovini A. Comparative evaluation of prophylactic SIV vaccination modalities administered to the oral cavity. Aids Research and Human Retroviruses. PMID 32962398 DOI: 10.1089/AID.2020.0157 |
0.054 |
|
2011 |
Novotny LA, Clements JD, Bakaletz LO. Transcutaneous immunization as preventative and therapeutic regimens to protect against experimental otitis media due to nontypeable Haemophilus influenzae. Mucosal Immunology. 4: 456-67. PMID 21326197 DOI: 10.1038/mi.2011.6 |
0.054 |
|
2007 |
McNeal MM, Basu M, Bean JA, Clements JD, Choi AH, Ward RL. Identification of an immunodominant CD4+ T cell epitope in the VP6 protein of rotavirus following intranasal immunization of BALB/c mice. Virology. 363: 410-8. PMID 17337285 DOI: 10.1016/j.virol.2007.01.041 |
0.054 |
|
2007 |
DuBois AB, Freytag LC, Clements JD. Evaluation of combinatorial vaccines against anthrax and plague in a murine model. Vaccine. 25: 4747-54. PMID 17482725 DOI: 10.1016/J.Vaccine.2007.03.048 |
0.053 |
|
1989 |
Sigwart DF, Stocker BA, Clements JD. Effect of a purA mutation on efficacy of Salmonella live-vaccine vectors. Infection and Immunity. 57: 1858-61. PMID 2722244 DOI: 10.1128/iai.57.6.1858-1861.1989 |
0.052 |
|
1996 |
Takahashi I, Marinaro M, Kiyono H, Jackson RJ, Nakagawa I, Fujihashi K, Hamada S, Clements JD, Bost KL, McGhee JR. Mechanisms for mucosal immunogenicity and adjuvancy of Escherichia coli labile enterotoxin. The Journal of Infectious Diseases. 173: 627-35. PMID 8627026 DOI: 10.1093/Infdis/173.3.627 |
0.052 |
|
1982 |
Clements JD, Flint DC, Klipstein FA. Immunological and physicochemical characterization of heat-labile enterotoxins isolated from two strains of Escherichia coli. Infection and Immunity. 38: 806-9. PMID 6183221 DOI: 10.1128/iai.38.2.806-809.1982 |
0.052 |
|
2001 |
Gerber S, Lane C, Brown DM, Lord E, DiLorenzo M, Clements JD, Rybicki E, Williamson AL, Rose RC. Human papillomavirus virus-like particles are efficient oral immunogens when coadministered with Escherichia coli heat-labile enterotoxin mutant R192G or CpG DNA. Journal of Virology. 75: 4752-60. PMID 11312347 DOI: 10.1128/Jvi.75.10.4752-4760.2001 |
0.052 |
|
1998 |
Chong C, Friberg M, Clements JD. LT(R192G), a non-toxic mutant of the heat-labile enterotoxin of Escherichia coli, elicits enhanced humoral and cellular immune responses associated with protection against lethal oral challenge with Salmonella spp. Vaccine. 16: 732-40. PMID 9562694 DOI: 10.1016/S0264-410X(97)00255-7 |
0.052 |
|
2007 |
McNeal MM, Basu M, Bean JA, Clements JD, Lycke NY, Ramne A, Löwenadler B, Choi AH, Ward RL. Intrarectal immunization of mice with VP6 and either LT(R192G) or CTA1-DD as adjuvant protects against fecal rotavirus shedding after EDIM challenge. Vaccine. 25: 6224-31. PMID 17629371 DOI: 10.1016/j.vaccine.2007.05.065 |
0.052 |
|
2019 |
Sui Y, Lewis GK, Wang Y, Berckmueller K, Frey B, Dzutsev A, Vargas-Inchaustegui D, Mohanram V, Musich T, Shen X, DeVico A, Fouts T, Venzon D, Kirk J, Waters RC, ... ... Clements J, et al. Mucosal vaccine efficacy against intrarectal SHIV is independent of anti-Env antibody response. The Journal of Clinical Investigation. PMID 30776026 DOI: 10.1172/Jci122110 |
0.052 |
|
1991 |
Bao JX, Clements JD. Prior immunologic experience potentiates the subsequent antibody response when Salmonella strains are used as vaccine carriers. Infection and Immunity. 59: 3841-5. PMID 1894383 DOI: 10.1128/iai.59.10.3841-3845.1991 |
0.051 |
|
2012 |
Hayden CA, Streatfield SJ, Lamphear BJ, Fake GM, Keener TK, Walker JH, Clements JD, Turner DD, Tizard IR, Howard JA. Bioencapsulation of the hepatitis B surface antigen and its use as an effective oral immunogen. Vaccine. 30: 2937-42. PMID 22406456 DOI: 10.1016/J.Vaccine.2012.02.072 |
0.051 |
|
1993 |
Cárdenas L, Clements JD. Stability, immunogenicity and expression of foreign antigens in bacterial vaccine vectors. Vaccine. 11: 126-35. PMID 8382417 DOI: 10.1016/0264-410X(93)90007-K |
0.05 |
|
2022 |
Sahoo A, Jones AT, Cheedarla N, Gangadhara S, Roy V, Styles TM, Shiferaw A, Walter KL, Williams LD, Shen X, Ozorowski G, Lee WH, Burton S, Yi L, Song X, ... ... Clements JD, et al. A clade C HIV-1 vaccine protects against heterologous SHIV infection by modulating IgG glycosylation and T helper response in macaques. Science Immunology. 7: eabl4102. PMID 35867800 DOI: 10.1126/sciimmunol.abl4102 |
0.05 |
|
2002 |
Martin M, Sharpe A, Clements JD, Michalek SM. Role of B7 costimulatory molecules in the adjuvant activity of the heat-labile enterotoxin of Escherichia coli. Journal of Immunology (Baltimore, Md. : 1950). 169: 1744-52. PMID 12165495 DOI: 10.4049/Jimmunol.169.4.1744 |
0.05 |
|
2010 |
Summerton NA, Welch RW, Bondoc L, Yang HH, Pleune B, Ramachandran N, Harris AM, Bland D, Jackson WJ, Park S, Clements JD, Nabors GS. Toward the development of a stable, freeze-dried formulation of Helicobacter pylori killed whole cell vaccine adjuvanted with a novel mutant of Escherichia coli heat-labile toxin. Vaccine. 28: 1404-11. PMID 19897067 DOI: 10.1016/j.vaccine.2009.10.147 |
0.05 |
|
2006 |
McNeal MM, Stone SC, Basu M, Bean JA, Clements JD, Hendrickson BA, Choi AH, Ward RL. Protection against rotavirus shedding after intranasal immunization of mice with a chimeric VP6 protein does not require intestinal IgA. Virology. 346: 338-47. PMID 16375942 DOI: 10.1016/j.virol.2005.11.016 |
0.049 |
|
2001 |
Tumpey TM, Renshaw M, Clements JD, Katz JM. Mucosal delivery of inactivated influenza vaccine induces B-cell-dependent heterosubtypic cross-protection against lethal influenza A H5N1 virus infection. Journal of Virology. 75: 5141-50. PMID 11333895 DOI: 10.1128/Jvi.75.11.5141-5150.2001 |
0.049 |
|
2013 |
Heine SJ, Diaz-McNair J, Martinez-Becerra FJ, Choudhari SP, Clements JD, Picking WL, Pasetti MF. Evaluation of immunogenicity and protective efficacy of orally delivered Shigella type III secretion system proteins IpaB and IpaD. Vaccine. 31: 2919-29. PMID 23644075 DOI: 10.1016/J.Vaccine.2013.04.045 |
0.049 |
|
1999 |
Ryan ET, Crean TI, John M, Butterton JR, Clements JD, Calderwood SB. In vivo expression and immunoadjuvancy of a mutant of heat-labile enterotoxin of Escherichia coli in vaccine and vector strains of Vibrio cholerae. Infection and Immunity. 67: 1694-701. PMID 10085006 DOI: 10.1128/IAI.67.4.1694-1701.1999 |
0.049 |
|
1996 |
Kincy-Cain T, Clements JD, Bost KL. Endogenous and exogenous interleukin-12 augment the protective immune response in mice orally challenged with Salmonella dublin. Infection and Immunity. 64: 1437-40. PMID 8606114 DOI: 10.1128/Iai.64.4.1437-1440.1996 |
0.048 |
|
2018 |
Clements JD, Perez Ruixo JJ, Gibbs JP, Doshi S, Perez Ruixo C, Melhem M. Receiver Operating Characteristic Analysis and Clinical Trial Simulation to Inform Dose Titration Decisions. Cpt: Pharmacometrics & Systems Pharmacology. PMID 30246497 DOI: 10.1002/psp4.12354 |
0.048 |
|
2011 |
Kreisberg RB, Harper J, Strauman MC, Marohn M, Clements JD, Nataro JP. Induction of increased permeability of polarized enterocyte monolayers by enterotoxigenic Escherichia coli heat-labile enterotoxin. The American Journal of Tropical Medicine and Hygiene. 84: 451-5. PMID 21363985 DOI: 10.4269/Ajtmh.2011.10-0445 |
0.048 |
|
2002 |
Lu X, Clements JD, Katz JM. Mutant Escherichia coli heat-labile enterotoxin [LT(R192G)] enhances protective humoral and cellular immune responses to orally administered inactivated influenza vaccine. Vaccine. 20: 1019-29. PMID 11803061 DOI: 10.1016/S0264-410X(01)00452-2 |
0.047 |
|
2007 |
Choi AH, Smiley K, Basu M, McNeal MM, Shao M, Bean JA, Clements JD, Stout RR, Ward RL. Protection of mice against rotavirus challenge following intradermal DNA immunization by Biojector needle-free injection. Vaccine. 25: 3215-8. PMID 17280754 DOI: 10.1016/j.vaccine.2007.01.035 |
0.047 |
|
1997 |
Bost KL, Hellner CF, Holton RH, Ratterree MS, Clements JD, Krogstad DJ, Kincy-Cain T. Reverse transcriptase-polymerase chain reaction amplification and partial sequence of T helper 1- and T helper 2-type lymphokine genes from the owl monkey (Aotus trivirgatus). The American Journal of Tropical Medicine and Hygiene. 56: 351-8. PMID 9129542 DOI: 10.4269/Ajtmh.1997.56.351 |
0.047 |
|
2019 |
Baker SM, Pociask D, Clements JD, McLachlan JB, Morici LA. Intradermal vaccination with a Pseudomonas aeruginosa vaccine adjuvanted with a mutant bacterial ADP-ribosylating enterotoxin protects against acute pneumonia. Vaccine. PMID 30638799 DOI: 10.1016/J.Vaccine.2018.12.053 |
0.047 |
|
1981 |
Klipstein FA, Engert RF, Clements JD. Immunization of rats with heat-labile enterotoxin provides uniform protection against heterologous serotypes of enterotoxigenic Escherichia coli. Infection and Immunity. 32: 1100-4. PMID 7019087 DOI: 10.1128/iai.32.3.1100-1104.1981 |
0.046 |
|
2019 |
Kuchimanchi M, Zhu M, Clements JD, Doshi S. Exposure-response analysis of blinatumomab in patients with relapsed/refractory acute lymphoblastic leukaemia and comparison with standard of care chemotherapy. British Journal of Clinical Pharmacology. PMID 30645768 DOI: 10.1111/bcp.13864 |
0.046 |
|
2002 |
Lemere CA, Spooner ET, Leverone JF, Mori C, Clements JD. Intranasal immunotherapy for the treatment of Alzheimer's disease: Escherichia coli LT and LT(R192G) as mucosal adjuvants. Neurobiology of Aging. 23: 991-1000. PMID 12470794 DOI: 10.1016/S0197-4580(02)00127-6 |
0.046 |
|
2015 |
Novotny LA, Clements JD, Bakaletz LO. Therapeutic transcutaneous immunization with a bandaid vaccine resolves experimental otitis media. Clinical and Vaccine Immunology : Cvi. PMID 26018536 DOI: 10.1128/CVI.00090-15 |
0.046 |
|
2007 |
McNeal MM, Stone SC, Basu M, Clements JD, Choi AH, Ward RL. IFN-gamma is the only anti-rotavirus cytokine found after in vitro stimulation of memory CD4+ T cells from mice immunized with a chimeric VP6 protein. Viral Immunology. 20: 571-84. PMID 18158731 DOI: 10.1089/vim.2007.0055 |
0.046 |
|
2014 |
Alam MM, Bufano MK, Xu P, Kalsy A, Yu Y, Freeman YW, Sultana T, Rashu MR, Desai I, Eckhoff G, Leung DT, Charles RC, LaRocque RC, Harris JB, Clements JD, et al. Evaluation in mice of a conjugate vaccine for cholera made from Vibrio cholerae O1 (Ogawa) O-specific polysaccharide. Plos Neglected Tropical Diseases. 8: e2683. PMID 24516685 DOI: 10.1371/Journal.Pntd.0002683 |
0.045 |
|
2016 |
Clements JD, Freytag LC. Parenteral Vaccination Can Be An Effective Means of Inducing Protective Mucosal Responses. Clinical and Vaccine Immunology : Cvi. PMID 27122485 DOI: 10.1128/Cvi.00214-16 |
0.044 |
|
2007 |
Lawson LB, Freytag LC, Clements JD. Use of nanocarriers for transdermal vaccine delivery. Clinical Pharmacology and Therapeutics. 82: 641-3. PMID 17998911 DOI: 10.1038/Sj.Clpt.6100425 |
0.044 |
|
2003 |
Warzecha H, Mason HS, Lane C, Tryggvesson A, Rybicki E, Williamson AL, Clements JD, Rose RC. Oral immunogenicity of human papillomavirus-like particles expressed in potato. Journal of Virology. 77: 8702-11. PMID 12885889 DOI: 10.1128/Jvi.77.16.8702-8711.2003 |
0.044 |
|
2014 |
Lundgren A, Bourgeois L, Carlin N, Clements J, Gustafsson B, Hartford M, Holmgren J, Petzold M, Walker R, Svennerholm AM. Safety and immunogenicity of an improved oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine administered alone and together with dmLT adjuvant in a double-blind, randomized, placebo-controlled Phase I study. Vaccine. 32: 7077-84. PMID 25444830 DOI: 10.1016/j.vaccine.2014.10.069 |
0.044 |
|
2006 |
Pahar B, Cantu MA, Zhao W, Kuroda MJ, Veazey RS, Montefiori DC, Clements JD, Aye PP, Lackner AA, Lovgren-Bengtsson K, Sestak K. Single epitope mucosal vaccine delivered via immuno-stimulating complexes induces low level of immunity against simian-HIV. Vaccine. 24: 6839-49. PMID 17050045 DOI: 10.1016/J.Vaccine.2006.06.050 |
0.044 |
|
1995 |
Takahashi I, Nakagawa I, Kiyono H, McGhee JR, Clements JD, Hamada S. Mucosal T cells induce systemic anergy for oral tolerance. Biochemical and Biophysical Research Communications. 206: 414-20. PMID 7818546 DOI: 10.1006/bbrc.1995.1057 |
0.044 |
|
2015 |
Norton EB, Bauer DL, Weldon WC, Oberste MS, Lawson LB, Clements JD. The novel adjuvant dmLT promotes dose sparing, mucosal immunity and longevity of antibody responses to the inactivated polio vaccine in a murine model. Vaccine. 33: 1909-15. PMID 25765967 DOI: 10.1016/J.Vaccine.2015.02.069 |
0.043 |
|
2000 |
Morris CB, Cheng E, Thanawastien A, Cárdenas-Freytag L, Clements JD. Effectiveness of intranasal immunization with HIV-gp160 and an HIV-1 env CTL epitope peptide (E7) in combination with the mucosal adjuvant LT(R192G). Vaccine. 18: 1944-51. PMID 10699345 DOI: 10.1016/S0264-410X(99)00447-8 |
0.043 |
|
2003 |
Ambrose Z, Thompson J, Larsen K, Kuller L, Panicali DL, Clements JD, Agy M, Montefiori DC, Hu SL, Bosch ML. Evidence for immune-mediated reduction of viral replication in Macaca nemestrina mucosally immunized with inactivated SHIV(89.6). Virology. 308: 178-90. PMID 12706101 DOI: 10.1016/S0042-6822(03)00027-8 |
0.042 |
|
2003 |
Lemere CA, Spooner ET, LaFrancois J, Malester B, Mori C, Leverone JF, Matsuoka Y, Taylor JW, DeMattos RB, Holtzman DM, Clements JD, Selkoe DJ, Duff KE. Evidence for peripheral clearance of cerebral Abeta protein following chronic, active Abeta immunization in PSAPP mice. Neurobiology of Disease. 14: 10-8. PMID 13678662 DOI: 10.1016/S0969-9961(03)00044-5 |
0.042 |
|
1998 |
Mason HS, Haq TA, Clements JD, Arntzen CJ. Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): potatoes expressing a synthetic LT-B gene. Vaccine. 16: 1336-43. PMID 9682399 DOI: 10.1016/S0264-410X(98)80020-0 |
0.042 |
|
2003 |
Leverone JF, Spooner ET, Lehman HK, Clements JD, Lemere CA. Aβ1-15 is less immunogenic than Aβ1-40/42 for intranasal immunization of wild-type mice but may be effective for "boosting" Vaccine. 21: 2206-2215. DOI: 10.1016/S0264-410X(02)00754-5 |
0.042 |
|
2012 |
Arifuzzaman M, Rashu R, Leung DT, Hosen MI, Bhuiyan TR, Bhuiyan MS, Rahman MA, Khanam F, Saha A, Charles RC, LaRocque RC, Weil AA, Clements JD, Holmes RK, Calderwood SB, et al. Antigen-specific memory T cell responses after vaccination with an oral killed cholera vaccine in Bangladeshi children and comparison to responses in patients with naturally acquired cholera. Clinical and Vaccine Immunology : Cvi. 19: 1304-11. PMID 22739692 DOI: 10.1128/Cvi.00196-12 |
0.041 |
|
2013 |
Clements JD, Connell ND, Dirks C, El-Faham M, Hay A, Heitman E, Stith JH, Bond EC, Colwell RR, Anestidou L, Husbands JL, Labov JB. Engaging actively with issues in the responsible conduct of science: lessons from international efforts are relevant for undergraduate education in the United States. Cbe Life Sciences Education. 12: 596-603. PMID 24297287 DOI: 10.1187/Cbe.13-09-0184 |
0.041 |
|
2004 |
Kristiansen T, Clements J, Baldwin D, Otto K. Options evaluated. Health Estate. 58: 44-52. PMID 14997793 |
0.041 |
|
2005 |
Glynn A, Roy CJ, Powell BS, Adamovicz JJ, Freytag LC, Clements JD. Protection against aerosolized Yersinia pestis challenge following homologous and heterologous prime-boost with recombinant plague antigens. Infection and Immunity. 73: 5256-61. PMID 16041052 DOI: 10.1128/Iai.73.8.5256-5261.2005 |
0.04 |
|
2011 |
Lawson LB, Norton EB, Clements JD. Defending the mucosa: adjuvant and carrier formulations for mucosal immunity. Current Opinion in Immunology. 23: 414-20. PMID 21511452 DOI: 10.1016/j.coi.2011.03.009 |
0.039 |
|
2005 |
Leavell S, Wright B, Scappino L, Sirriyah J, Chen C, Clements JD, Burkhard MJ. Induction of serum and mucosal FIV-specific immune responses by intranasal immunization with p24Gag. Vaccine. 23: 1471-8. PMID 15670883 DOI: 10.1016/j.vaccine.2004.09.017 |
0.039 |
|
2012 |
Tomchuck SL, Norton EB, Garry RF, Bunnell BA, Morris CA, Freytag LC, Clements JD. Mesenchymal stem cells as a novel vaccine platform. Frontiers in Cellular and Infection Microbiology. 2: 140. PMID 23162801 DOI: 10.3389/Fcimb.2012.00140 |
0.038 |
|
2010 |
Thiam F, Martino CD, Bon F, Charpilienne A, Cachia C, Poncet D, Clements JD, Basset C, Kohli E. Unexpected modulation of recall B and T cell responses after immunization with rotavirus-like particles in the presence of LT-R192G. Toxins. 2: 2007-27. PMID 22069670 DOI: 10.3390/toxins2082007 |
0.038 |
|
1980 |
Alving CR, Banerji B, Shiba T, Kotani S, Clements JD, Richards RL. Liposomes as vehicles for vaccines. Progress in Clinical and Biological Research. 47: 339-55. PMID 7208512 |
0.038 |
|
2003 |
Leverone JF, Spooner ET, Lehman HK, Clements JD, Lemere CA. Abeta1-15 is less immunogenic than Abeta1-40/42 for intranasal immunization of wild-type mice but may be effective for "boosting". Vaccine. 21: 2197-206. PMID 12706711 |
0.036 |
|
2010 |
Lee S, Belitsky BR, Brinker JP, Kerstein KO, Brown DW, Clements JD, Keusch GT, Tzipori S, Sonenshein AL, Herrmann JE. Development of a Bacillus subtilis-based rotavirus vaccine. Clinical and Vaccine Immunology : Cvi. 17: 1647-55. PMID 20810679 DOI: 10.1128/Cvi.00135-10 |
0.036 |
|
1998 |
O'Neal CM, Clements JD, Estes MK, Conner ME. Rotavirus 2/6 viruslike particles administered intranasally with cholera toxin, Escherichia coli heat-labile toxin (LT), and LT-R192G induce protection from rotavirus challenge. Journal of Virology. 72: 3390-3. PMID 9525668 DOI: 10.1128/JVI.72.4.3390-3393.1998 |
0.036 |
|
1996 |
Bost KL, Holton RH, Cain TK, Clements JD. In vivo treatment with anti-interleukin-13 antibodies significantly reduces the humoral immune response against an oral immunogen in mice. Immunology. 87: 633-41. PMID 8675220 DOI: 10.1046/J.1365-2567.1996.502574.X |
0.035 |
|
2016 |
Taxt AM, Diaz Y, Aasland R, Clements JD, Nataro JP, Sommerfelt H, Puntervoll P. Towards rational design of a toxoid vaccine against the heat-stable toxin of Escherichia coli. Infection and Immunity. PMID 26883587 DOI: 10.1128/Iai.01225-15 |
0.035 |
|
2001 |
Belyakov IM, Hel Z, Kelsall B, Kuznetsov VA, Ahlers JD, Nacsa J, Watkins DI, Allen TM, Sette A, Altman J, Woodward R, Markham PD, Clements JD, Franchini G, Strober W, et al. Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques. Nature Medicine. 7: 1320-6. PMID 11726972 DOI: 10.1038/Nm1201-1320 |
0.035 |
|
2019 |
Harro C, Louis Bourgeois A, Sack D, Walker R, DeNearing B, Brubaker J, Maier N, Fix A, Dally L, Chakraborty S, Clements JD, Saunders I, Darsley MJ. Live attenuated enterotoxigenic Escherichia coli (ETEC) vaccine with dmLT adjuvant protects human volunteers against virulent experimental ETEC challenge. Vaccine. PMID 30797634 DOI: 10.1016/j.vaccine.2019.02.025 |
0.035 |
|
2002 |
McNeal MM, VanCott JL, Choi AH, Basu M, Flint JA, Stone SC, Clements JD, Ward RL. CD4 T cells are the only lymphocytes needed to protect mice against rotavirus shedding after intranasal immunization with a chimeric VP6 protein and the adjuvant LT(R192G). Journal of Virology. 76: 560-8. PMID 11752147 DOI: 10.1128/JVI.76.2.560-568.2002 |
0.034 |
|
1981 |
Klipstein FA, Engert RF, Clements JD. Protection in rats immunized with Escherichia coli heat-stable enterotoxin. Infection and Immunity. 34: 637-9. PMID 7030964 DOI: 10.1128/iai.34.2.637-639.1981 |
0.034 |
|
1993 |
Walker RI, Clements JD. Use of heat-labile toxin of enterotoxigenic Escherichia coli to Facilitate mucosal immunization Vaccine Research. 2: 1-10. |
0.033 |
|
2000 |
Belyakov IM, Ahlers JD, Clements JD, Strober W, Berzofsky JA. Interplay of cytokines and adjuvants in the regulation of mucosal and systemic HIV-specific CTL. Journal of Immunology (Baltimore, Md. : 1950). 165: 6454-62. PMID 11086085 DOI: 10.4049/jimmunol.165.11.6454 |
0.032 |
|
2010 |
Lawson LB, Clements JD, Freytag LC. Mucosal Immune Responses Induced by Transcutaneous Vaccines. Current Topics in Microbiology and Immunology. PMID 21061198 DOI: 10.1007/82_2010_113 |
0.031 |
|
1987 |
Clements JD. Use of attenuated mutants of Salmonella as carriers for delivery of heterologous antigens to the secretory immune system. Pathology and Immunopathology Research. 6: 137-46. PMID 3321020 DOI: 10.1159/000157055 |
0.031 |
|
2012 |
Lule E, Iddings E, Manandhar L, Grandhi B, Clements J. Utility of Analgesic and Anxiolytic Medication Dose during Colonoscopy in Identifying Patients with Irritable Bowel Syndrome. Isrn Gastroenterology. 2012: 969015. PMID 22272379 DOI: 10.5402/2012/969015 |
0.03 |
|
2012 |
Agarwal R, Saluja P, Pham A, Ledbetter K, Bains S, Varghese S, Clements J, Kim YH. The effect of CyberKnife therapy on pulmonary function tests used for treating non-small cell lung cancer: a retrospective, observational cohort pilot study. Cancer Management and Research. 4: 347-50. PMID 23091397 DOI: 10.2147/CMAR.S34194 |
0.028 |
|
2013 |
Sjökvist Ottsjö L, Flach CF, Clements J, Holmgren J, Raghavan S. A double mutant heat-labile toxin from Escherichia coli, LT(R192G/L211A), is an effective mucosal adjuvant for vaccination against Helicobacter pylori infection. Infection and Immunity. 81: 1532-40. PMID 23439305 DOI: 10.1128/IAI.01407-12 |
0.026 |
|
1999 |
Freytag LC, Clements JD. Bacterial toxins as mucosal adjuvants. Current Topics in Microbiology and Immunology. 236: 215-36. PMID 9893362 DOI: 10.1007/978-3-642-59951-4_11 |
0.021 |
|
2010 |
Tan G, Xu P, Lawson LB, He J, Freytag LC, Clements JD, John VT. Hydration effects on skin microstructure as probed by high-resolution cryo-scanning electron microscopy and mechanistic implications to enhanced transcutaneous delivery of biomacromolecules. Journal of Pharmaceutical Sciences. 99: 730-40. PMID 19582754 DOI: 10.1002/Jps.21863 |
0.021 |
|
2021 |
Nooney J, Thor S, de Vries C, Clements J, Sahin L, Hua W, Everett D, Zaccaria C, Ball R, Saint-Raymond A, Yao L, Raine J, Kweder S. Assuring Access to Safe Medicines in Pregnancy and Breastfeeding. Clinical Pharmacology and Therapeutics. PMID 33615448 DOI: 10.1002/cpt.2212 |
0.02 |
|
2019 |
Clements JD, Zhu M, Kuchimanchi M, Terminello B, Doshi S. Population Pharmacokinetics of Blinatumomab in Pediatric and Adult Patients with Hematological Malignancies. Clinical Pharmacokinetics. PMID 31679130 DOI: 10.1007/s40262-019-00823-8 |
0.019 |
|
1997 |
Clements JD. Surface warfare against pathogens using mucosal vaccines. Nature Biotechnology. 15: 622-3. PMID 9219260 DOI: 10.1038/nbt0797-622 |
0.017 |
|
2015 |
Freytag LC, Clements JD. Mucosal Adjuvants: New Developments and Challenges Mucosal Immunology: Fourth Edition. 1: 1183-1199. DOI: 10.1016/B978-0-12-415847-4.00061-6 |
0.013 |
|
2019 |
Lange A, Clements J. Soap Box. Contemporary Nurse. 2: 143-144. PMID 29134889 DOI: 10.1080/10376178.1993.11001388 |
0.013 |
|
2005 |
Dehority W, Lu KW, Clements J, Goerke J, Pittet JF, Allen L, Taeusch HW. Polyethylene glycol-surfactant for lavage lung injury in rats. Pediatric Research. 58: 913-8. PMID 16183815 DOI: 10.1203/01.Pdr.0000182581.39561.01 |
0.013 |
|
2021 |
Clements JD, Gorman GH, Waters CN, Lane HC. Tackling the burden of mumps in the military: A report of the Defense Health Board. Vaccine. 39: 6186-6188. PMID 34556365 DOI: 10.1016/j.vaccine.2021.09.006 |
0.01 |
|
2020 |
Bohner A, Topham C, Strunck J, Haynes D, Brazil M, Clements J, Simpson E, Chamberlain W. Dupilumab-Associated Ocular Surface Disease: Clinical Characteristics, Treatment, and Follow-Up. Cornea. PMID 32826648 DOI: 10.1097/Ico.0000000000002461 |
0.01 |
|
2013 |
Knapps J, Ghanem M, Clements J, Merchant AM. A systematic review of staple-line reinforcement in laparoscopic sleeve gastrectomy. Jsls : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons. 17: 390-9. PMID 24018075 DOI: 10.4293/108680813X13654754534639 |
0.01 |
|
2013 |
Kim R, Baumgartner N, Clements J. Routine left atrial appendage ligation during cardiac surgery may prevent postoperative atrial fibrillation-related cerebrovascular accident. The Journal of Thoracic and Cardiovascular Surgery. 145: 582-9; discussion 58. PMID 23137520 DOI: 10.1016/j.jtcvs.2012.10.016 |
0.01 |
|
1982 |
Clements JD. Computer leasing investments provide two-income families inflation hedge, added revenue. Nephrology Nurse. 4: 34-5. PMID 6919764 |
0.01 |
|
1968 |
Clements JD. The residential care facility. Indications for placement. Pediatric Clinics of North America. 15: 1029-39. PMID 4883200 |
0.01 |
|
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