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Peter Dedon, M.D., Ph.D. - Publications

Affiliations: 
Biological Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Biological chemistry of nucleic acids
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Pollo-Oliveira L, Davis N, Hossain I, Ho P, Yuan Y, García PS, Pereira C, Byrne SR, Leng J, Sze M, Blaby-Haas CE, Sekowska A, Montoya A, Begley T, Danchin A, ... ... Dedon PC, et al. The absence of the Queuosine tRNA modification leads to pleiotropic phenotypes revealing perturbations of metal and oxidative stress homeostasis in Escherichia coli K12. Metallomics : Integrated Biometal Science. PMID 36066904 DOI: 10.1093/mtomcs/mfac065  0.604
2021 Hu JF, Yim D, Ma D, Huber SM, Davis N, Bacusmo JM, Vermeulen S, Zhou J, Begley TJ, DeMott MS, Levine SS, de Crécy-Lagard V, Dedon PC, Cao B. Quantitative mapping of the cellular small RNA landscape with AQRNA-seq. Nature Biotechnology. PMID 33859402 DOI: 10.1038/s41587-021-00874-y  0.592
2020 Lutz T, Czapinska H, Fomenkov A, Potapov V, Heiter DF, Cao B, Dedon P, Bochtler M, Xu SY. Protein Domain Guided Screen for Sequence Specific and Phosphorothioate-Dependent Restriction Endonucleases. Frontiers in Microbiology. 11: 1960. PMID 33013736 DOI: 10.3389/Fmicb.2020.01960  0.303
2020 Tavares JF, Davis NK, Poim A, Reis A, Kellner S, Sousa I, Soares AR, Moura GMR, Dedon PC, Santos MAS. tRNA-modifying enzyme mutations induce codon-specific mistranslation and protein aggregation in yeast. Rna Biology. PMID 32893724 DOI: 10.1080/15476286.2020.1819671  0.617
2020 Pollo-Oliveira L, Klassen R, Davis N, Ciftci A, Bacusmo JM, Martinelli M, DeMott MS, Begley TJ, Dedon PC, Schaffrath R, de Crécy-Lagard V. Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast. Biomolecules. 10. PMID 32085421 DOI: 10.3390/biom10020322  0.625
2015 Cao B, Zheng X, Cheng Q, Yao F, Zheng T, Ramesh Babu I, Zhou H, Dedon P, You D. In vitro analysis of phosphorothioate modification of DNA reveals substrate recognition by a multiprotein complex. Scientific Reports. 5: 12513. PMID 26213215 DOI: 10.1038/Srep12513  0.323
2013 Mangerich A, Dedon PC, Fox JG, Tannenbaum SR, Wogan GN. Chemistry meets biology in colitis-associated carcinogenesis. Free Radical Research. 47: 958-86. PMID 23926919 DOI: 10.3109/10715762.2013.832239  0.44
2013 Knutson CG, Mangerich A, Zeng Y, Raczynski AR, Liberman RG, Kang P, Ye W, Prestwich EG, Lu K, Wishnok JS, Korzenik JR, Wogan GN, Fox JG, Dedon PC, Tannenbaum SR. Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E2332-41. PMID 23754421 DOI: 10.1073/Pnas.1222669110  0.437
2013 Prestwich EG, Mangerich A, Pang B, McFaline JL, Lonkar P, Sullivan MR, Trudel LJ, Taghizedeh K, Dedon PC. Increased levels of inosine in a mouse model of inflammation. Chemical Research in Toxicology. 26: 538-46. PMID 23506120 DOI: 10.1021/Tx300473N  0.321
2013 Cui L, Ye W, Prestwich EG, Wishnok JS, Taghizadeh K, Dedon PC, Tannenbaum SR. Comparative analysis of four oxidized guanine lesions from reactions of DNA with peroxynitrite, singlet oxygen, and γ-radiation. Chemical Research in Toxicology. 26: 195-202. PMID 23140136 DOI: 10.1021/Tx300294D  0.494
2012 Lim KS, Cui L, Taghizadeh K, Wishnok JS, Chan W, DeMott MS, Babu IR, Tannenbaum SR, Dedon PC. In situ analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine oxidation reveals sequence- and agent-specific damage spectra. Journal of the American Chemical Society. 134: 18053-64. PMID 23057664 DOI: 10.1021/Ja307525H  0.489
2012 Wogan GN, Dedon PC, Tannenbaum SR, Fox JG. Infection, inflammation and colon carcinogenesis. Oncotarget. 3: 737-8. PMID 22964519 DOI: 10.18632/Oncotarget.624  0.493
2012 Mangerich A, Knutson CG, Parry NM, Muthupalani S, Ye W, Prestwich E, Cui L, McFaline JL, Mobley M, Ge Z, Taghizadeh K, Wishnok JS, Wogan GN, Fox JG, Tannenbaum SR, ... Dedon PC, et al. Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: E1820-9. PMID 22689960 DOI: 10.1073/Pnas.1207829109  0.497
2012 Cadet J, Loft S, Olinski R, Evans MD, Bialkowski K, Richard Wagner J, Dedon PC, Møller P, Greenberg MM, Cooke MS. Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids. Free Radical Research. 46: 367-81. PMID 22263561 DOI: 10.3109/10715762.2012.659248  0.395
2010 Fox JG, Feng Y, Theve EJ, Raczynski AR, Fiala JL, Doernte AL, Williams M, McFaline JL, Essigmann JM, Schauer DB, Tannenbaum SR, Dedon PC, Weinman SA, Lemon SM, Fry RC, et al. Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens. Gut. 59: 88-97. PMID 19850960 DOI: 10.1136/Gut.2009.183749  0.392
2010 Lim KS, Cui L, Taghizadeh K, Wishnok JS, Shafirovich V, Geacintov NE, Tannenbaum SR, Dedon PC. The Spectrum of 8-oxoguanine Oxidation Products is both Sequence and Oxidant Dependent Free Radical Biology and Medicine. 49: S168. DOI: 10.1016/J.Freeradbiomed.2010.10.477  0.422
2007 Pang B, Zhou X, Yu H, Dong M, Taghizadeh K, Wishnok JS, Tannenbaum SR, Dedon PC. Lipid peroxidation dominates the chemistry of DNA adduct formation in a mouse model of inflammation. Carcinogenesis. 28: 1807-13. PMID 17347141 DOI: 10.1093/Carcin/Bgm037  0.5
2006 Dong M, Vongchampa V, Gingipalli L, Cloutier JF, Kow YW, O'Connor T, Dedon PC. Development of enzymatic probes of oxidative and nitrosative DNA damage caused by reactive nitrogen species. Mutation Research. 594: 120-34. PMID 16274707 DOI: 10.1016/j.mrfmmm.2005.08.008  0.301
2005 Li CQ, Wright TL, Dong M, Dommels YE, Trudel LJ, Dedon PC, Tannenbaum SR, Wogan GN. Biological role of glutathione in nitric oxide-induced toxicity in cell culture and animal models. Free Radical Biology & Medicine. 39: 1489-98. PMID 16274884 DOI: 10.1016/J.Freeradbiomed.2005.07.011  0.471
2005 Zhou X, Liberman RG, Skipper PL, Margolin Y, Tannenbaum SR, Dedon PC. Quantification of DNA strand breaks and abasic sites by oxime derivatization and accelerator mass spectrometry: application to gamma-radiation and peroxynitrite. Analytical Biochemistry. 343: 84-92. PMID 15964542 DOI: 10.1016/J.Ab.2005.05.007  0.47
2004 Dedon PC, Tannenbaum SR. Reactive nitrogen species in the chemical biology of inflammation. Archives of Biochemistry and Biophysics. 423: 12-22. PMID 14989259 DOI: 10.1016/J.Abb.2003.12.017  0.479
2000 Tretyakova NY, Burney S, Pamir B, Wishnok JS, Dedon PC, Wogan GN, Tannenbaum SR. Peroxynitrite-induced DNA damage in the supF gene: correlation with the mutational spectrum. Mutation Research. 447: 287-303. PMID 10751613 DOI: 10.1016/S0027-5107(99)00221-3  0.503
1999 Burney S, Niles JC, Dedon PC, Tannenbaum SR. DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite Chemical Research in Toxicology. 12: 513-520. PMID 10368314 DOI: 10.1021/Tx980254M  0.5
1997 Kennedy LJ, Moore K, Caulfield JL, Tannenbaum SR, Dedon PC. Quantitation of 8-oxoguanine and strand breaks produced by four oxidizing agents Chemical Research in Toxicology. 10: 386-392. PMID 9114974 DOI: 10.1021/Tx960102W  0.46
1988 Qazi R, Chang AY, Borch RF, Montine T, Dedon P, Loughner J, Bennett JM. Phase I clinical and pharmacokinetic study of diethyldithiocarbamate as a chemoprotector from toxic effects of cisplatin. Journal of the National Cancer Institute. 80: 1486-8. PMID 2846857 DOI: 10.1093/Jnci/80.18.1486  0.543
1987 Dedon PC, Borch RF. Characterization of the reactions of platinum antitumor agents with biologic and nonbiologic sulfur-containing nucleophiles. Biochemical Pharmacology. 36: 1955-64. PMID 2954556 DOI: 10.1016/0006-2952(87)90494-1  0.537
1986 Bodenner DL, Dedon PC, Keng PC, Katz JC, Borch RF. Selective protection against cis-diamminedichloroplatinum(II)-induced toxicity in kidney, gut, and bone marrow by diethyldithiocarbamate. Cancer Research. 46: 2751-5. PMID 3009000  0.519
1986 Bodenner DL, Dedon PC, Keng PC, Borch RF. Effect of diethyldithiocarbamate on cis-diamminedichloroplatinum(II)-induced cytotoxicity, DNA cross-linking, and gamma-glutamyl transpeptidase inhibition. Cancer Research. 46: 2745-50. PMID 2870800  0.558
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