Joshua Dunaief, MD/PhD - Publications

Ophthalmology University of Pennsylvania, Philadelphia, PA, United States 

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Shu W, Baumann BH, Song Y, Liu Y, Wu X, Dunaief JL. Iron Accumulates in Retinal Vascular Endothelial Cells But Has Minimal Retinal Penetration After IP Iron Dextran Injection in Mice. Investigative Ophthalmology & Visual Science. 60: 4378-4387. PMID 31634395 DOI: 10.1167/iovs.19-28250  0.52
2019 Khan RS, Baumann B, Dine K, Song Y, Dunaief JL, Kim SF, Shindler KS. Dexras1 Deletion and Iron Chelation Promote Neuroprotection in Experimental Optic Neuritis. Scientific Reports. 9: 11664. PMID 31406150 DOI: 10.1038/s41598-019-48087-3  0.52
2019 Baumann BH, Shu W, Song Y, Simpson EM, Lakhal-Littleton S, Dunaief JL. Ferroportin-mediated iron export from vascular endothelial cells in retina and brain. Experimental Eye Research. 107728. PMID 31323276 DOI: 10.1016/j.exer.2019.107728  0.52
2019 Baumann BH, Shu W, Song Y, Sterling J, Kozmik Z, Littleton-Lakhal S, Dunaief JL. Liver-Specific but Not Retina-Specific Hepcidin Knockout Causes Retinal Iron Accumulation and Degeneration. The American Journal of Pathology. PMID 31287995 DOI: 10.1016/j.ajpath.2019.05.022  0.52
2019 Schultz H, Song Y, Baumann BH, Kapphahn RJ, Montezuma SR, Ferrington DA, Dunaief JL. Increased serum proteins in non-exudative AMD retinas. Experimental Eye Research. PMID 31158383 DOI: 10.1016/j.exer.2019.05.026  0.52
2019 Kim BJ, Grossman M, Song D, Saludades S, Pan W, Dominguez-Perez S, Dunaief JL, Aleman TS, Ying GS, Irwin DJ. Persistent and Progressive Outer Retina Thinning in Frontotemporal Degeneration. Frontiers in Neuroscience. 13: 298. PMID 31019447 DOI: 10.3389/fnins.2019.00298  1
2019 Ueda Y, Miwa T, Ito D, Kim H, Sato S, Gullipalli D, Zhou L, Golla M, Song D, Dunaief JL, Palmer MB, Song WC. Differential contribution of C5aR and C5b-9 pathways to renal thrombic microangiopathy and macrovascular thrombosis in mice carrying an atypical hemolytic syndrome-related factor H mutation. Kidney International. PMID 30910380 DOI: 10.1016/j.kint.2019.01.009  1
2019 Song D, Ueda Y, Bhuyan R, Mohammed I, Miwa T, Gullipali D, Kim H, Zhou L, Song Y, Schultz H, Bargoud A, Dunaief JL, Song WC. Complement Factor H Mutation W1206R Causes Retinal Thrombosis and Ischemic Retinopathy in Mice. The American Journal of Pathology. PMID 30711487 DOI: 10.1016/j.ajpath.2019.01.009  1
2018 Daniel E, Ying GS, Kim BJ, Toth CA, Ferris F, Martin DF, Grunwald JE, Jaffe GJ, Dunaief JL, Pan W, Maguire MG. Follow up at 5 Years of Non-Fibrotic Scars in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology. PMID 30476517 DOI: 10.1016/j.ophtha.2018.11.020  0.36
2018 Saadane A, Petrov A, Mast N, El-Darzi N, Dao T, Alnemri A, Song Y, Dunaief JL, Pikuleva IA. Mechanisms that minimize retinal impact of apolipoprotein E absence. Journal of Lipid Research. PMID 30333155 DOI: 10.1194/jlr.M090043  0.52
2018 Song D, Mohammed I, Bhuyan R, Miwa T, Williams AL, Gullipalli D, Sato S, Song Y, Dunaief JL, Song WC. Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease. Investigative Ophthalmology & Visual Science. 59: 3405-3415. PMID 30025090 DOI: 10.1167/iovs.18-24133  1
2018 Ueda K, Kim HJ, Zhao J, Song Y, Dunaief JL, Sparrow JR. Iron promotes oxidative cell death caused by bisretinoids of retina. Proceedings of the National Academy of Sciences of the United States of America. PMID 29686088 DOI: 10.1073/pnas.1722601115  0.52
2017 Kim BJ, Irwin DJ, Song D, Daniel E, Leveque JD, Raquib AR, Pan W, Ying GS, Aleman TS, Dunaief JL, Grossman M. Optical coherence tomography identifies outer retina thinning in frontotemporal degeneration. Neurology. PMID 28887373 DOI: 10.1212/WNL.0000000000004500  1
2017 Baumann B, Sterling J, Song Y, Song D, Fruttiger M, Gillies M, Shen W, Dunaief JL. Conditional Müller Cell Ablation Leads to Retinal Iron Accumulation. Investigative Ophthalmology & Visual Science. 58: 4223-4234. PMID 28846772 DOI: 10.1167/iovs.17-21743  1
2017 Qi S, Wang C, Song D, Song Y, Dunaief JL. Intraperitoneal injection of (-)-Epigallocatechin-3-gallate protects against light-induced photoreceptor degeneration in the mouse retina. Molecular Vision. 23: 171-178. PMID 28458506  1
2017 Song D, Sulewski ME, Wang C, Song J, Bhuyan R, Sterling J, Clark E, Song WC, Dunaief JL. Complement C5a receptor knockout has diminished light-induced microglia/macrophage retinal migration. Molecular Vision. 23: 210-218. PMID 28442885  1
2017 Ueda Y, Mohammed I, Song D, Gullipalli D, Zhou L, Sato S, Wang Y, Gupta S, Cheng Z, Wang H, Bao J, Mao Y, Brass L, Zheng XL, Miwa T, ... ... Dunaief J, et al. Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation. Blood. PMID 28057640 DOI: 10.1182/blood-2016-07-728253  1
2017 Sterling J, Guttha S, Song Y, Song D, Hadziahmetovic M, Dunaief JL. Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels. Experimental Eye Research. PMID 28057442 DOI: 10.1016/j.exer.2016.12.008  1
2016 Song D, Wilson B, Zhao L, Bhuyan R, Bandyopadhyay M, Lyubarsky A, Yu C, Li Y, Kanu L, Miwa T, Song WC, Finnemann SC, Rohrer B, Dunaief JL. Retinal Pre-Conditioning by CD59a Knockout Protects against Light-Induced Photoreceptor Degeneration. Plos One. 11: e0166348. PMID 27893831 DOI: 10.1371/journal.pone.0166348  1
2016 Sarezky D, Raquib AR, Dunaief JL, Kim BJ. Tolerability in the elderly population of high-dose alpha lipoic acid: a potential antioxidant therapy for the eye. Clinical Ophthalmology (Auckland, N.Z.). 10: 1899-1903. PMID 27729766 DOI: 10.2147/OPTH.S115900  0.32
2016 Song D, Kanu LN, Li Y, Kelly KL, Bhuyan RK, Aleman T, Morgan JI, Dunaief JL. AMD-like retinopathy associated with intravenous iron. Experimental Eye Research. PMID 27565570 DOI: 10.1016/j.exer.2016.08.008  1
2015 Theurl M, Song D, Clark E, Sterling J, Grieco S, Altamura S, Galy B, Hentze M, Muckenthaler MU, Dunaief JL. Mice with hepcidin-resistant ferroportin accumulate iron in the retina. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26506980 DOI: 10.1096/fj.15-276758  1
2015 Song D, Song J, Wang C, Li Y, Dunaief JL. Berberine protects against light-induced photoreceptor degeneration in the mouse retina. Experimental Eye Research. PMID 26475979 DOI: 10.1016/j.exer.2015.10.005  1
2015 Bhoiwala DL, Dunaief JL. Retinal abnormalities in β-thalassemia major. Survey of Ophthalmology. PMID 26325202 DOI: 10.1016/j.survophthal.2015.08.005  1
2015 Zhao L, Hadziahmetovic M, Wang C, Xu X, Song Y, Jinnah HA, Wodzinska J, Iacovelli J, Wolkow N, Krajacic P, Cwanger Weissberger A, Connelly J, Spino M, Lee MK, Connor J, ... ... Dunaief JL, et al. Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone. Journal of Neurochemistry. PMID 26303407 DOI: 10.1111/jnc.13292  1
2015 Bhoiwala DL, Song Y, Cwanger A, Clark E, Zhao LL, Wang C, Li Y, Song D, Dunaief JL. CD1 Mouse Retina Is Shielded From Iron Overload Caused by a High Iron Diet. Investigative Ophthalmology & Visual Science. 56: 5344-52. PMID 26275132 DOI: 10.1167/iovs.15-17026  1
2015 Yao J, Jia L, Khan N, Lin C, Mitter SK, Boulton ME, Dunaief JL, Klionsky DJ, Guan JL, Thompson DA, Zacks DN. Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium. Autophagy. 11: 939-53. PMID 26075877 DOI: 10.1080/15548627.2015.1041699  1
2015 Gelfand BD, Wright CB, Kim Y, Yasuma T, Yasuma R, Li S, Fowler BJ, Bastos-Carvalho A, Kerur N, Uittenbogaard A, Han YS, Lou D, Kleinman ME, McDonald WH, Núñez G, ... ... Dunaief JL, et al. Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome. Cell Reports. 11: 1686-93. PMID 26074074 DOI: 10.1016/j.celrep.2015.05.023  1
2015 Choi SY, Baek JI, Zuo X, Kim SH, Dunaief JL, Lipschutz JH. Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Investigative Ophthalmology & Visual Science. 56: 3361-70. PMID 26024121 DOI: 10.1167/iovs.14-15692  1
2015 Hunter AA, Smit-McBride Z, Anderson R, Bordbari MH, Ying GS, Kim ES, Park SS, Telander DG, Dunaief JL, Hjelmeland LM, Morse LS. GSTM1 and GSTM5 Genetic Polymorphisms and Expression in Age-Related Macular Degeneration. Current Eye Research. 1-7. PMID 25897651 DOI: 10.3109/02713683.2015.1016179  1
2015 Li Y, Song D, Song Y, Zhao L, Wolkow N, Tobias JW, Song W, Dunaief JL. Iron-induced Local Complement Component 3 (C3) Up-regulation via Non-canonical Transforming Growth Factor (TGF)-β Signaling in the Retinal Pigment Epithelium. The Journal of Biological Chemistry. 290: 11918-34. PMID 25802332 DOI: 10.1074/jbc.M115.645903  1
2015 Jiang R, Hua C, Wan Y, Jiang B, Hu H, Zheng J, Fuqua BK, Dunaief JL, Anderson GJ, David S, Vulpe CD, Chen H. Hephaestin and ceruloplasmin play distinct but interrelated roles in iron homeostasis in mouse brain. The Journal of Nutrition. 145: 1003-9. PMID 25788583 DOI: 10.3945/jn.114.207316  1
2014 Guo LY, Alekseev O, Li Y, Song Y, Dunaief JL. Iron increases APP translation and amyloid-beta production in the retina. Experimental Eye Research. 129: 31-7. PMID 25456519 DOI: 10.1016/j.exer.2014.10.012  1
2014 Wolkow N, Li Y, Maminishkis A, Song Y, Alekseev O, Iacovelli J, Song D, Lee JC, Dunaief JL. Iron upregulates melanogenesis in cultured retinal pigment epithelial cells. Experimental Eye Research. 128: 92-101. PMID 25277027 DOI: 10.1016/j.exer.2014.09.010  1
2014 Zhao L, Li Y, Song D, Song Y, Theurl M, Wang C, Cwanger A, Su G, Dunaief JL. A high serum iron level causes mouse retinal iron accumulation despite an intact blood-retinal barrier. The American Journal of Pathology. 184: 2862-7. PMID 25174877 DOI: 10.1016/j.ajpath.2014.07.008  1
2014 Zhao L, Wang C, Song D, Li Y, Song Y, Su G, Dunaief JL. Systemic administration of the antioxidant/iron chelator α-lipoic acid protects against light-induced photoreceptor degeneration in the mouse retina. Investigative Ophthalmology & Visual Science. 55: 5979-88. PMID 25146987 DOI: 10.1167/iovs.14-15025  1
2014 Song D, Grieco S, Li Y, Hunter A, Chu S, Zhao L, Song Y, DeAngelis RA, Shi LY, Liu Q, Pierce EA, Nishina PM, Lambris JD, Dunaief JL. A murine RP1 missense mutation causes protein mislocalization and slowly progressive photoreceptor degeneration. The American Journal of Pathology. 184: 2721-9. PMID 25088982 DOI: 10.1016/j.ajpath.2014.06.010  1
2014 Song D, Zhao L, Li Y, Hadziahmetovic M, Song Y, Connelly J, Spino M, Dunaief JL. The oral iron chelator deferiprone protects against systemic iron overload-induced retinal degeneration in hepcidin knockout mice. Investigative Ophthalmology & Visual Science. 55: 4525-32. PMID 24970260 DOI: 10.1167/iovs.14-14568  1
2014 Fuqua BK, Lu Y, Darshan D, Frazer DM, Wilkins SJ, Wolkow N, Bell AG, Hsu J, Yu CC, Chen H, Dunaief JL, Anderson GJ, Vulpe CD. The multicopper ferroxidase hephaestin enhances intestinal iron absorption in mice. Plos One. 9: e98792. PMID 24896847 DOI: 10.1371/journal.pone.0098792  1
2014 He L, Marioutina M, Dunaief JL, Marneros AG. Age- and gene-dosage-dependent cre-induced abnormalities in the retinal pigment epithelium. The American Journal of Pathology. 184: 1660-7. PMID 24854863 DOI: 10.1016/j.ajpath.2014.02.007  1
2014 Masuda T, Wahlin K, Wan J, Hu J, Maruotti J, Yang X, Iacovelli J, Wolkow N, Kist R, Dunaief JL, Qian J, Zack DJ, Esumi N. Transcription factor SOX9 plays a key role in the regulation of visual cycle gene expression in the retinal pigment epithelium. The Journal of Biological Chemistry. 289: 12908-21. PMID 24634209 DOI: 10.1074/jbc.M114.556738  1
2014 Dunaief D, Cwanger A, Dunaief JL. Iron-Induced Retinal Damage Handbook of Nutrition, Diet and the Eye. 619-626. DOI: 10.1016/B978-0-12-401717-7.00063-0  1
2013 Song D, Dunaief JL. Retinal iron homeostasis in health and disease. Frontiers in Aging Neuroscience. 5: 24. PMID 23825457 DOI: 10.3389/fnagi.2013.00024  1
2013 Chen Y, Khan RS, Cwanger A, Song Y, Steenstra C, Bang S, Cheah JH, Dunaief J, Shindler KS, Snyder SH, Kim SF. Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3582-7. PMID 23426685 DOI: 10.1523/JNEUROSCI.1497-12.2013  1
2012 Hadziahmetovic M, Pajic M, Grieco S, Song Y, Song D, Li Y, Cwanger A, Iacovelli J, Chu S, Ying GS, Connelly J, Spino M, Dunaief JL. The Oral Iron Chelator Deferiprone Protects Against Retinal Degeneration Induced through Diverse Mechanisms. Translational Vision Science & Technology. 1: 2. PMID 24049709 DOI: 10.1167/tvst.1.3.2  1
2012 Hadziahmetovic M, Pajic M, Grieco S, Song Y, Song D, Li Y, Cwanger A, Iacovelli J, Chu S, Ying GS, Connelly J, Spino M, Dunaief JL. The Oral Iron Chelator Deferiprone Protects Against Retinal Degeneration Induced through Diverse Mechanisms. Translational Vision Science & Technology. 1: 7. PMID 24049707 DOI: 10.1167/tvst.1.2.7  1
2012 Hadziahmetovic M, Kumar U, Song Y, Grieco S, Song D, Li Y, Tobias JW, Dunaief JL. Microarray analysis of murine retinal light damage reveals changes in iron regulatory, complement, and antioxidant genes in the neurosensory retina and isolated RPE. Investigative Ophthalmology & Visual Science. 53: 5231-41. PMID 22736611 DOI: 10.1167/iovs.12-10204  1
2012 Song D, Song Y, Hadziahmetovic M, Zhong Y, Dunaief JL. Systemic administration of the iron chelator deferiprone protects against light-induced photoreceptor degeneration in the mouse retina. Free Radical Biology & Medicine. 53: 64-71. PMID 22579919 DOI: 10.1016/j.freeradbiomed.2012.04.020  1
2012 Tarallo V, Hirano Y, Gelfand BD, Dridi S, Kerur N, Kim Y, Cho WG, Kaneko H, Fowler BJ, Bogdanovich S, Albuquerque RJ, Hauswirth WW, Chiodo VA, Kugel JF, Goodrich JA, ... ... Dunaief JL, et al. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell. 149: 847-59. PMID 22541070 DOI: 10.1016/j.cell.2012.03.036  1
2012 Hunter A, Spechler PA, Cwanger A, Song Y, Zhang Z, Ying GS, Hunter AK, Dezoeten E, Dunaief JL. DNA methylation is associated with altered gene expression in AMD. Investigative Ophthalmology & Visual Science. 53: 2089-105. PMID 22410570 DOI: 10.1167/iovs.11-8449  1
2012 Wolkow N, Song D, Song Y, Chu S, Hadziahmetovic M, Lee JC, Iacovelli J, Grieco S, Dunaief JL. Ferroxidase hephaestin's cell-autonomous role in the retinal pigment epithelium. The American Journal of Pathology. 180: 1614-24. PMID 22342521 DOI: 10.1016/j.ajpath.2011.12.041  1
2012 Mehta S, Bunya VY, Orlin SE, Sulewski ME, Dunaief JL. A significant drug-drug interaction detected through corneal examination: resolution of cornea verticillata while using amiodarone. Cornea. 31: 81-3. PMID 21941175 DOI: 10.1097/ICO.0b013e3182107c8e  1
2011 Wolkow N, Song Y, Wu TD, Qian J, Guerquin-Kern JL, Dunaief JL. Aceruloplasminemia: retinal histopathologic manifestations and iron-mediated melanosome degradation. Archives of Ophthalmology (Chicago, Ill. : 1960). 129: 1466-74. PMID 22084216 DOI: 10.1001/archophthalmol.2011.309  1
2011 Leed MG, Wolkow N, Pham DM, Daniel CL, Dunaief JL, Franz KJ. Prochelators triggered by hydrogen peroxide provide hexadentate iron coordination to impede oxidative stress. Journal of Inorganic Biochemistry. 105: 1161-72. PMID 21708101 DOI: 10.1016/j.jinorgbio.2011.05.023  1
2011 Hadziahmetovic M, Song Y, Wolkow N, Iacovelli J, Kautz L, Roth MP, Dunaief JL. Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration. The American Journal of Pathology. 179: 335-48. PMID 21703414 DOI: 10.1016/j.ajpath.2011.03.033  1
2011 Dunaief JL. Ironing out neurodegeneration: iron chelation for neuroprotection. Free Radical Biology & Medicine. 51: 1480-1. PMID 21616141 DOI: 10.1016/j.freeradbiomed.2011.05.009  1
2011 Kaneko H, Dridi S, Tarallo V, Gelfand BD, Fowler BJ, Cho WG, Kleinman ME, Ponicsan SL, Hauswirth WW, Chiodo VA, Karikó K, Yoo JW, Lee DK, Hadziahmetovic M, Song Y, ... ... Dunaief JL, et al. DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature. 471: 325-30. PMID 21297615 DOI: 10.1038/nature09830  1
2011 Iacovelli J, Zhao C, Wolkow N, Veldman P, Gollomp K, Ojha P, Lukinova N, King A, Feiner L, Esumi N, Zack DJ, Pierce EA, Vollrath D, Dunaief JL. Generation of Cre transgenic mice with postnatal RPE-specific ocular expression. Investigative Ophthalmology & Visual Science. 52: 1378-83. PMID 21212186 DOI: 10.1167/iovs.10-6347  1
2011 Zhao C, Yasumura D, Li X, Matthes M, Lloyd M, Nielsen G, Ahern K, Snyder M, Bok D, Dunaief JL, LaVail MM, Vollrath D. mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice. The Journal of Clinical Investigation. 121: 369-83. PMID 21135502 DOI: 10.1172/JCI44303  1
2011 Hadziahmetovic M, Song Y, Wolkow N, Iacovelli J, Grieco S, Lee J, Lyubarsky A, Pratico D, Connelly J, Spino M, Harris ZL, Dunaief JL. The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration. Investigative Ophthalmology & Visual Science. 52: 959-68. PMID 21051716 DOI: 10.1167/iovs.10-6207  1
2011 Hadziahmetovic M, Song Y, Ponnuru P, Iacovelli J, Hunter A, Haddad N, Beard J, Connor JR, Vaulont S, Dunaief JL. Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice. Investigative Ophthalmology & Visual Science. 52: 109-18. PMID 20811044 DOI: 10.1167/iovs.10-6113  1
2010 Xu W, Grunwald JE, Metelitsina TI, DuPont JC, Ying GS, Martin ER, Dunaief JL, Brucker AJ. Association of risk factors for choroidal neovascularization in age-related macular degeneration with decreased foveolar choroidal circulation. American Journal of Ophthalmology. 150: 40-47.e2. PMID 20493466 DOI: 10.1016/j.ajo.2010.01.041  1
2009 Iacovelli J, Mlodnicka AE, Veldman P, Ying GS, Dunaief JL, Schumacher A. Brain and retinal ferroportin 1 dysregulation in polycythaemia mice. Brain Research. 1289: 85-95. PMID 19596281 DOI: 10.1016/j.brainres.2009.06.098  1
2009 Hahn P, Song Y, Ying GS, He X, Beard J, Dunaief JL. Age-dependent and gender-specific changes in mouse tissue iron by strain. Experimental Gerontology. 44: 594-600. PMID 19563877 DOI: 10.1016/j.exger.2009.06.006  1
2009 Lukinova N, Iacovelli J, Dentchev T, Wolkow N, Hunter A, Amado D, Ying GS, Sparrow JR, Dunaief JL. Iron chelation protects the retinal pigment epithelial cell line ARPE-19 against cell death triggered by diverse stimuli. Investigative Ophthalmology & Visual Science. 50: 1440-7. PMID 19182262 DOI: 10.1167/iovs.08-2545  1
2009 Loh A, Hadziahmetovic M, Dunaief JL. Iron homeostasis and eye disease. Biochimica Et Biophysica Acta. 1790: 637-49. PMID 19059309 DOI: 10.1016/j.bbagen.2008.11.001  1
2008 Charkoudian LK, Dentchev T, Lukinova N, Wolkow N, Dunaief JL, Franz KJ. Iron prochelator BSIH protects retinal pigment epithelial cells against cell death induced by hydrogen peroxide. Journal of Inorganic Biochemistry. 102: 2130-5. PMID 18835041 DOI: 10.1016/j.jinorgbio.2008.08.001  1
2008 Shoham A, Hadziahmetovic M, Dunaief JL, Mydlarski MB, Schipper HM. Oxidative stress in diseases of the human cornea. Free Radical Biology & Medicine. 45: 1047-55. PMID 18718524 DOI: 10.1016/j.freeradbiomed.2008.07.021  1
2008 Bhisitkul RB, Winn BJ, Lee OT, Wong J, Pereira Dde S, Porco TC, He X, Hahn P, Dunaief JL. Neuroprotective effect of intravitreal triamcinolone acetonide against photoreceptor apoptosis in a rabbit model of subretinal hemorrhage. Investigative Ophthalmology & Visual Science. 49: 4071-7. PMID 18421081 DOI: 10.1167/iovs.08-1892  1
2008 Hadziahmetovic M, Dentchev T, Song Y, Haddad N, He X, Hahn P, Pratico D, Wen R, Harris ZL, Lambris JD, Beard J, Dunaief JL. Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD. Investigative Ophthalmology & Visual Science. 49: 2728-36. PMID 18326691 DOI: 10.1167/iovs.07-1472  1
2008 Metelitsina TI, Grunwald JE, DuPont JC, Ying GS, Brucker AJ, Dunaief JL. Foveolar choroidal circulation and choroidal neovascularization in age-related macular degeneration. Investigative Ophthalmology & Visual Science. 49: 358-63. PMID 18172113 DOI: 10.1167/iovs.07-0526  1
2007 Wong RW, Richa DC, Hahn P, Green WR, Dunaief JL. Iron toxicity as a potential factor in AMD. Retina (Philadelphia, Pa.). 27: 997-1003. PMID 18040235 DOI: 10.1097/IAE.0b013e318074c290  1
2007 He X, Hahn P, Iacovelli J, Wong R, King C, Bhisitkul R, Massaro-Giordano M, Dunaief JL. Iron homeostasis and toxicity in retinal degeneration. Progress in Retinal and Eye Research. 26: 649-73. PMID 17921041 DOI: 10.1016/j.preteyeres.2007.07.004  1
2007 Dentchev T, Yao Y, Pratico D, Dunaief J. Isoprostane F2alpha-VI, a new marker of oxidative stress, increases following light damage to the mouse retina. Molecular Vision. 13: 190-5. PMID 17327824  1
2006 Hahn P, Ying GS, Beard J, Dunaief JL. Iron levels in human retina: sex difference and increase with age. Neuroreport. 17: 1803-6. PMID 17164668 DOI: 10.1097/WNR.0b013e3280107776  1
2006 Dunaief JL. Iron induced oxidative damage as a potential factor in age-related macular degeneration: the Cogan Lecture. Investigative Ophthalmology & Visual Science. 47: 4660-4. PMID 17065470 DOI: 10.1167/iovs.06-0568  1
2006 Krajacic P, Qian Y, Hahn P, Dentchev T, Lukinova N, Dunaief JL. Retinal localization and copper-dependent relocalization of the Wilson and Menkes disease proteins. Investigative Ophthalmology & Visual Science. 47: 3129-34. PMID 16799059 DOI: 10.1167/iovs.05-1601  1
2006 Chowers I, Wong R, Dentchev T, Farkas RH, Iacovelli J, Gunatilaka TL, Medeiros NE, Presley JB, Campochiaro PA, Curcio CA, Dunaief JL, Zack DJ. The iron carrier transferrin is upregulated in retinas from patients with age-related macular degeneration. Investigative Ophthalmology & Visual Science. 47: 2135-40. PMID 16639025 DOI: 10.1167/iovs.05-1135  1
2006 Glazer-Hockstein C, Dunaief JL. Could blue light-blocking lenses decrease the risk of age-related macular degeneration? Retina (Philadelphia, Pa.). 26: 1-4. PMID 16395131 DOI: 10.1097/00006982-200601000-00001  1
2005 Dentchev T, Hahn P, Dunaief JL. Strong labeling for iron and the iron-handling proteins ferritin and ferroportin in the photoreceptor layer in age-related macular degeneration. Archives of Ophthalmology (Chicago, Ill. : 1960). 123: 1745-6. PMID 16344450 DOI: 10.1001/archopht.123.12.1745  1
2005 Hahn P, Lindsten T, Tolentino M, Thompson CB, Bennett J, Dunaief JL. Persistent fetal ocular vasculature in mice deficient in bax and bak. Archives of Ophthalmology (Chicago, Ill. : 1960). 123: 797-802. PMID 15955981 DOI: 10.1001/archopht.123.6.797  1
2005 Dunaief JL, Richa C, Franks EP, Schultze RL, Aleman TS, Schenck JF, Zimmerman EA, Brooks DG. Macular degeneration in a patient with aceruloplasminemia, a disease associated with retinal iron overload. Ophthalmology. 112: 1062-5. PMID 15882908 DOI: 10.1016/j.ophtha.2004.12.029  1
2004 Rex TS, Tsui I, Hahn P, Maguire AM, Duan D, Bennett J, Dunaief JL. Adenovirus-mediated delivery of catalase to retinal pigment epithelial cells protects neighboring photoreceptors from photo-oxidative stress. Human Gene Therapy. 15: 960-7. PMID 15585111 DOI: 10.1089/hum.2004.15.960  1
2004 Howes KA, Liu Y, Dunaief JL, Milam A, Frederick JM, Marks A, Baehr W. Receptor for advanced glycation end products and age-related macular degeneration. Investigative Ophthalmology & Visual Science. 45: 3713-20. PMID 15452081 DOI: 10.1167/iovs.04-0404  1
2004 Hahn P, Qian Y, Dentchev T, Chen L, Beard J, Harris ZL, Dunaief JL. Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 101: 13850-5. PMID 15365174 DOI: 10.1073/pnas.0405146101  1
2004 Hahn P, Dentchev T, Qian Y, Rouault T, Harris ZL, Dunaief JL. Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina. Molecular Vision. 10: 598-607. PMID 15354085  1
2004 Chen L, Wu W, Dentchev T, Wong R, Dunaief JL. Increased metallothionein in light damaged mouse retinas. Experimental Eye Research. 79: 287-93. PMID 15325575 DOI: 10.1016/j.exer.2004.05.004  1
2004 Chen L, Wu W, Dentchev T, Zeng Y, Wang J, Tsui I, Tobias JW, Bennett J, Baldwin D, Dunaief JL. Light damage induced changes in mouse retinal gene expression. Experimental Eye Research. 79: 239-47. PMID 15325571 DOI: 10.1016/j.exer.2004.05.002  1
2004 Hahn P, Lindsten T, Lyubarsky A, Ying GS, Pugh EN, Thompson CB, Dunaief JL. Deficiency of Bax and Bak protects photoreceptors from light damage in vivo. Cell Death and Differentiation. 11: 1192-7. PMID 15272317 DOI: 10.1038/sj.cdd.4401486  1
2004 King A, Gottlieb E, Brooks DG, Murphy MP, Dunaief JL. Mitochondria-derived reactive oxygen species mediate blue light-induced death of retinal pigment epithelial cells. Photochemistry and Photobiology. 79: 470-5. PMID 15191057 DOI: 10.1562/LE-03-17.1  1
2003 Hahn P, Milam AH, Dunaief JL. Maculas affected by age-related macular degeneration contain increased chelatable iron in the retinal pigment epithelium and Bruch's membrane. Archives of Ophthalmology (Chicago, Ill. : 1960). 121: 1099-105. PMID 12912686 DOI: 10.1001/archopht.121.8.1099  1
2003 Hahn P, Lindsten T, Ying GS, Bennett J, Milam AH, Thompson CB, Dunaief JL. Proapoptotic bcl-2 family members, Bax and Bak, are essential for developmental photoreceptor apoptosis. Investigative Ophthalmology & Visual Science. 44: 3598-605. PMID 12882813 DOI: 10.1167/iovs.02-1113  1
2003 Dentchev T, Milam AH, Lee VM, Trojanowski JQ, Dunaief JL. Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas. Molecular Vision. 9: 184-90. PMID 12764254  1
2003 Chen L, Dentchev T, Wong R, Hahn P, Wen R, Bennett J, Dunaief JL. Increased expression of ceruloplasmin in the retina following photic injury. Molecular Vision. 9: 151-8. PMID 12724641  1
2002 Dunaief JL, King A, Esumi N, Eagen M, Dentchev T, Sung CH, Chen S, Zack DJ. Protein Phosphatase 1 binds strongly to the retinoblastoma protein but not to p107 or p130 in vitro and in vivo. Current Eye Research. 24: 392-6. PMID 12434308 DOI: 10.1076/ceyr.24.5.392.8524  1
2002 Dunaief JL, Dentchev T, Ying GS, Milam AH. The role of apoptosis in age-related macular degeneration. Archives of Ophthalmology (Chicago, Ill. : 1960). 120: 1435-42. PMID 12427055  1
2002 Witschel H, Sundmacher R, Dunaief J, Ng EWN, Goldberg MF. Epithelial origin of "stromal" corneal dystrophies [2] (multiple letters) Archives of Ophthalmology. 120: 101. PMID 11786073  1
2001 Dunaief JL, Conway J, Rigamonti D, Goldberg MF. Retinal venous telangiectasia and anastomoses with cerebellar venous and cavernous malformation. Retina (Philadelphia, Pa.). 21: 262-5. PMID 11421019  1
2001 Dunaief JL, Ng EW, Goldberg MF. Corneal dystrophies of epithelial genesis: the possible therapeutic use of limbal stem cell transplantation. Archives of Ophthalmology (Chicago, Ill. : 1960). 119: 120-2. PMID 11146737  1
1996 Strober BE, Dunaief JL, Guha, Goff SP. Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteins. Molecular and Cellular Biology. 16: 1576-83. PMID 8657132  1
1995 Dunaief JL, Kwun RC, Bhardwaj N, Lopez R, Gouras P, Goff SP. Retroviral gene transfer into retinal pigment epithelial cells followed by transplantation into rat retina. Human Gene Therapy. 6: 1225-9. PMID 8527481 DOI: 10.1089/hum.1995.6.9-1225  1
1994 Dunaief JL, Strober BE, Guha S, Khavari PA, Alin K, Luban J, Begemann M, Crabtree GR, Goff SP. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell. 79: 119-30. PMID 7923370 DOI: 10.1016/0092-8674(94)90405-7  1
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