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Bekir Cinar, Ph.D. - Publications

Affiliations: 
2002 University of Virginia, Charlottesville, VA 
Area:
Biochemistry, Molecular Biology, Cell Biology, Oncology
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44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Boston AM, Dwead AM, Al-Mathkour MM, Khazaw K, Zou J, Zhang Q, Wang G, Cinar B. Discordant interactions between YAP1 and polycomb group protein SCML2 determine cell fate. Iscience. 26: 107964. PMID 37810219 DOI: 10.1016/j.isci.2023.107964  0.306
2022 Al-Mathkour MM, Dwead AM, Alp E, Boston AM, Cinar B. The Hippo effector YAP1/TEAD1 regulates EPHA3 expression to control cell contact and motility. Scientific Reports. 12: 3840. PMID 35264657 DOI: 10.1038/s41598-022-07790-4  0.355
2021 Cinar B, Alp E, Al-Mathkour M, Boston A, Dwead A, Khazaw K, Gregory A. The Hippo pathway: an emerging role in urologic cancers. American Journal of Clinical and Experimental Urology. 9: 301-317. PMID 34541029  0.435
2020 Cinar B, Al-Mathkour MM, Khan SA, Moreno CS. Androgen attenuates the inactivating phospho-Ser-127 modification of yes-associated protein 1 (YAP1) and promotes YAP1 nuclear abundance and activity. The Journal of Biological Chemistry. PMID 32376689 DOI: 10.1074/Jbc.Ra120.013794  0.597
2019 Pickett IR, Boston AM, Almathkour MM, Ragin C, Bilen MA, Osunkoya AO, Cinar B. Abstract 1022: The role of dopamine signaling in prostate cancer disparities Endocrinology. DOI: 10.1158/1538-7445.Sabcs18-1022  0.484
2019 Al-Mathkour MM, Cinar B. Abstract 2634: The role of Eph A receptor 3 tyrosine kinase signaling in prostate cancer progression Cancer Research. 79: 2634-2634. DOI: 10.1158/1538-7445.Am2019-2634  0.607
2018 George A, Raji I, Cinar B, Kucuk O, Oyelere AK. Design, synthesis, and evaluation of the antiproliferative activity of hydantoin-derived antiandrogen-genistein conjugates. Bioorganic & Medicinal Chemistry. PMID 29456113 DOI: 10.1016/J.Bmc.2018.01.009  0.542
2018 Cinar B, Moreno CS. Abstract 4373: AR signaling in concert with PP2A/B regulates YAP1 expression in prostate cancer cells Cancer Research. 78: 4373-4373. DOI: 10.1158/1538-7445.Am2018-4373  0.639
2017 Mohanty SK, Yagiz K, Pradhan D, Luthringer DJ, Amin MB, Alkan S, Cinar B. STAT3 and STAT5A are potential therapeutic targets in castration-resistant prostate cancer. Oncotarget. 8: 85997-86010. PMID 29156772 DOI: 10.18632/Oncotarget.20844  0.544
2017 Ready D, Yagiz K, Amin P, Yildiz Y, Funari V, Bozdag S, Cinar B. Mapping the STK4/Hippo signaling network in prostate cancer cell. Plos One. 12: e0184590. PMID 28880957 DOI: 10.1371/Journal.Pone.0184590  0.559
2017 Mohanty SK, Yagiz K, Luthringer L, Amin MB, Alkan S, Cinar B. Abstract 5707: STAT3 and STAT5a are potential therapeutic targets in castration-resistant prostate cancer Cancer Research. 77: 5707-5707. DOI: 10.1158/1538-7445.Am2017-5707  0.555
2016 Ready D, Yildiz Y, Funari V, Bozdag S, Cinar B. Abstract 4401: Disclosing the Hippo signaling networks in castration-resistant prostate cancer Cancer Research. 76: 4401-4401. DOI: 10.1158/1538-7445.Am2016-4401  0.597
2015 Kuser-Abali G, Alptekin A, Lewis M, Garraway IP, Cinar B. YAP1 and AR interactions contribute to the switch from androgen-dependent to castration-resistant growth in prostate cancer. Nature Communications. 6: 8126. PMID 28230103 DOI: 10.1038/Ncomms9126  0.616
2015 Cinar M, Rosenfelt F, Rokhsar S, Lopategui J, Pillai R, Cervania M, Pao A, Cinar B, Alkan S. Concurrent inhibition of MYC and BCL2 is a potentially effective treatment strategy for double hit and triple hit B-cell lymphomas. Leukemia Research. 39: 730-8. PMID 25916698 DOI: 10.1016/J.Leukres.2015.04.003  0.35
2015 Cinar M, Rosenfelt F, Rokshar S, Pillai R, Lopategui J, Cervania M, Cinar B, Alkan S. Abstract B12: Co-targeting of MYC and BCL2 signaling is a promising treatment strategy for double hit and triple hit B-cell lymphomas Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-B12  0.405
2015 Cinar M, Peker D, Akyurek N, Huang Q, Lopategui J, Cinar B, Alkan S. Abstract B11: Expression and functional analysis of aurora kinase A/B in double hit and triple hit B-cell lymphomas Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-B11  0.378
2015 Cinar B, Abali GK, Lewis M, Morrissey C, Garraway I. Abstract 1956: A subset of prostate cancer cells with loss of MST1 expression confers resistance to castration through YAP1-AR interactions Cancer Research. 75: 1956-1956. DOI: 10.1158/1538-7445.Am2015-1956  0.533
2015 Kuser-Abali G, Alptekin A, Lewis M, Garraway IP, Cinar B. YAP1 and AR interactions contribute to the switch from androgen-dependent to castration-resistant growth in prostate cancer Nature Communications. 6. DOI: 10.1038/ncomms9126  0.445
2014 Kuser-Abali G, Alptekin A, Cinar B. Overexpression of MYC and EZH2 cooperates to epigenetically silence MST1 expression. Epigenetics. 9: 634-43. PMID 24499724 DOI: 10.4161/Epi.27957  0.511
2014 Mukhopadhyay NK, Kim J, You S, Morello M, Hager MH, Huang WC, Ramachandran A, Yang J, Cinar B, Rubin MA, Adam RM, Oesterreich S, Di Vizio D, Freeman MR. Scaffold attachment factor B1 regulates the androgen receptor in concert with the growth inhibitory kinase MST1 and the methyltransferase EZH2. Oncogene. 33: 3235-45. PMID 23893242 DOI: 10.1038/Onc.2013.294  0.59
2014 Abali GK, Alptekin A, Cinar B. Abstract 1377: Transcriptional silencing of MST1/Hippo by a coordinated MYC and EZH2 signaling in prostate cancer Cancer Research. 74: 1377-1377. DOI: 10.1158/1538-7445.Am2014-1377  0.569
2013 Cinar M, Hamedani F, Mo Z, Cinar B, Amin HM, Alkan S. Bruton tyrosine kinase is commonly overexpressed in mantle cell lymphoma and its attenuation by Ibrutinib induces apoptosis. Leukemia Research. 37: 1271-7. PMID 23962569 DOI: 10.1016/J.Leukres.2013.07.028  0.441
2013 Alptekin A, Abali GK, Wang Q, Cinar B. Abstract 759: Regulation of androgenic signaling by yes-associated protein, YAP, in prostate cancer cells. Cancer Research. 73: 759-759. DOI: 10.1158/1538-7445.Am2013-759  0.602
2013 Cinar B, Alptekin A, Natale RB. Abstract 5251: Role of mammalian Hippo Mst1/2 protein kinase signaling in lung cancer progression. Cancer Research. 73: 5251-5251. DOI: 10.1158/1538-7445.Am2013-5251  0.39
2012 Collak FK, Yagiz K, Luthringer DJ, Erkaya B, Cinar B. Threonine-120 phosphorylation regulated by phosphoinositide-3-kinase/Akt and mammalian target of rapamycin pathway signaling limits the antitumor activity of mammalian sterile 20-like kinase 1. The Journal of Biological Chemistry. 287: 23698-709. PMID 22619175 DOI: 10.1074/Jbc.M112.358713  0.617
2012 Soifer HS, Souleimanian N, Wu S, Voskresenskiy AM, Collak FK, Cinar B, Stein CA. Direct regulation of androgen receptor activity by potent CYP17 inhibitors in prostate cancer cells. The Journal of Biological Chemistry. 287: 3777-87. PMID 22174412 DOI: 10.1074/Jbc.M111.261933  0.545
2011 Cinar B, Collak FK, Lopez D, Akgul S, Mukhopadhyay NK, Kilicarslan M, Gioeli DG, Freeman MR. MST1 is a multifunctional caspase-independent inhibitor of androgenic signaling. Cancer Research. 71: 4303-13. PMID 21512132 DOI: 10.1158/0008-5472.Can-10-4532  0.603
2011 Collak FK, Luthringer D, Kim HL, Chung L, Cinar B. Abstract 2928: Regulation of MST1 and MST2 by mTOR and androgen receptor signaling in prostate cancer Cancer Research. 71: 2928-2928. DOI: 10.1158/1538-7445.Am2011-2928  0.583
2010 Mukhopadhyay N, Hager M, Kim J, Vizio DD, Nichols A, Lopez D, Cinar B, Adam R, Oesterreich S, Freeman M. 1295 Scaffold Attachment Factor B1 Is An Androgen Receptor Co-Repressor And Mediates Association Of The Akt1 And Mst1 Kinases With Chromatin The Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.879  0.388
2009 Mukhopadhyay NK, Kim J, Cinar B, Ramachandran A, Hager MH, Di Vizio D, Adam RM, Rubin MA, Raychaudhuri P, De Benedetti A, Freeman MR. Heterogeneous nuclear ribonucleoprotein K is a novel regulator of androgen receptor translation. Cancer Research. 69: 2210-8. PMID 19258514 DOI: 10.1158/0008-5472.Can-08-2308  0.508
2008 Mukhopadhyay N, Kim J, Cinar B, Ramachandran A, Hager M, Adam RM, Raychaudhuri P, De Benedetti A, Freeman MR. HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K IS A NOVEL REGULATOR OF ANDROGEN RECEPTOR TRANSLATION IN PROSTATE CANCER Journal of Urology. 179: 187-187. DOI: 10.1016/S0022-5347(08)60542-X  0.35
2007 Cinar B, Fang PK, Lutchman M, Di Vizio D, Adam RM, Pavlova N, Rubin MA, Yelick PC, Freeman MR. The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1. The Embo Journal. 26: 4523-34. PMID 17932490 DOI: 10.1038/Sj.Emboj.7601872  0.505
2007 Cinar B, Mukhopadhyay NK, Meng G, Freeman MR. Phosphoinositide 3-kinase-independent non-genomic signals transit from the androgen receptor to Akt1 in membrane raft microdomains. The Journal of Biological Chemistry. 282: 29584-93. PMID 17635910 DOI: 10.1074/Jbc.M703310200  0.53
2007 Adam RM, Mukhopadhyay NK, Kim J, Di Vizio D, Cinar B, Boucher K, Solomon KR, Freeman MR. Cholesterol sensitivity of endogenous and myristoylated Akt. Cancer Research. 67: 6238-46. PMID 17616681 DOI: 10.1158/0008-5472.Can-07-0288  0.4
2007 Mukhopadhyay NK, Cinar B, Mukhopadhyay L, Lutchman M, Ferdinand AS, Kim J, Chung LW, Adam RM, Ray SK, Leiter AB, Richie JP, Liu BC, Freeman MR. The zinc finger protein ras-responsive element binding protein-1 is a coregulator of the androgen receptor: implications for the role of the Ras pathway in enhancing androgenic signaling in prostate cancer. Molecular Endocrinology (Baltimore, Md.). 21: 2056-70. PMID 17550981 DOI: 10.1210/Me.2006-0503  0.548
2007 Freeman MR, Cinar B, Kim J, Mukhopadhyay NK, Di Vizio D, Adam RM, Solomon KR. Transit of hormonal and EGF receptor-dependent signals through cholesterol-rich membranes. Steroids. 72: 210-7. PMID 17173942 DOI: 10.1016/J.Steroids.2006.11.012  0.455
2006 Mukhopadhyay NK, Ferdinand AS, Mukhopadhyay L, Cinar B, Lutchman M, Richie JP, Freeman MR, Liu BC. Unraveling androgen receptor interactomes by an array-based method: discovery of proto-oncoprotein c-Rel as a negative regulator of androgen receptor. Experimental Cell Research. 312: 3782-95. PMID 17011549 DOI: 10.1016/J.Yexcr.2006.07.017  0.486
2005 Freeman MR, Cinar B, Lu ML. Membrane rafts as potential sites of nongenomic hormonal signaling in prostate cancer. Trends in Endocrinology and Metabolism: Tem. 16: 273-9. PMID 16002302 DOI: 10.1016/J.Tem.2005.06.002  0.513
2005 Cinar B, De Benedetti A, Freeman MR. Post-transcriptional regulation of the androgen receptor by Mammalian target of rapamycin. Cancer Research. 65: 2547-53. PMID 15805247 DOI: 10.1158/0008-5472.Can-04-3411  0.546
2004 Cinar B, Yeung F, Konaka H, Mayo MW, Freeman MR, Zhau HE, Chung LW. Identification of a negative regulatory cis-element in the enhancer core region of the prostate-specific antigen promoter: implications for intersection of androgen receptor and nuclear factor-kappaB signalling in prostate cancer cells. The Biochemical Journal. 379: 421-31. PMID 14715080 DOI: 10.1042/Bj20031661  0.454
2003 Davis R, Jia D, Cinar B, Sikka SC, Moparty K, Zhau HE, Chung LW, Agrawal KC, Abdel-Mageed AB. Functional androgen receptor confers sensitization of androgen-independent prostate cancer cells to anticancer therapy via caspase activation. Biochemical and Biophysical Research Communications. 309: 937-45. PMID 13679064 DOI: 10.1016/J.Bbrc.2003.08.096  0.552
2001 Ye Q, Cinar B, Edlund M, Chung LWK, Zhau HE. Inhibition of growth and cell cycle arrest of ARCaP human prostate cancer cells by ectopic expression of ER-α Molecular and Cellular Biochemistry. 228: 105-110. PMID 11855735 DOI: 10.1023/A:1013303414460  0.515
2001 Cinar B, Koeneman KS, Edlund M, Prins GS, Zhau HE, Chung LWK. Androgen receptor mediates the reduced tumor growth, enhanced androgen responsiveness, and selected target gene transactivation in a human prostate cancer cell line Cancer Research. 61: 7310-7317. PMID 11585771  0.508
2000 Ye Q, Chung LWK, Cinar B, Li S, Zhau HE. Identification and characterization of estrogen receptor variants in prostate cancer cell lines Journal of Steroid Biochemistry and Molecular Biology. 75: 21-31. PMID 11179905 DOI: 10.1016/S0960-0760(00)00118-7  0.409
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