Miriam H. Meisler - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Genetics, Neuroscience Biology

198 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lenk GM, Park YN, Lemons R, Flynn E, Plank M, Frei CM, Davis MJ, Gregorka B, Swanson JA, Meisler MH, Kitzman JO. CRISPR knockout screen implicates three genes in lysosome function. Scientific Reports. 9: 9609. PMID 31270356 DOI: 10.1038/s41598-019-45939-w  0.52
2019 Bissig C, Croisé P, Heiligenstein X, Hurbain I, Lenk GM, Kaufman E, Sannerud R, Annaert W, Meisler MH, Weisman LS, Raposo G, van Niel G. Correction: The PIKfyve complex regulates the early melanosome homeostasis required for physiological amyloid formation (doi:10.1242/jcs.229500). Journal of Cell Science. 132. PMID 30923131 DOI: 10.1242/jcs.231746  0.52
2019 Lenk GM, Berry IR, Stutterd CA, Blyth M, Green L, Vadlamani G, Warren D, Craven I, Fanjul-Fernandez M, Rodriguez-Casero V, Lockhart PJ, Vanderver A, Simons C, Gibb S, Sadedin S, ... ... Meisler MH, et al. Cerebral hypomyelination associated with biallelic variants of FIG. 4. Human Mutation. PMID 30740813 DOI: 10.1002/humu.23720  0.52
2019 Bissig C, Croisé P, Heiligenstein X, Hurbain I, Lenk GM, Kaufman E, Sannerud R, Annaert W, Meisler MH, Weisman LS, Raposo G, van Niel G. PIKfyve complex regulates early melanosome homeostasis required for physiological amyloid formation. Journal of Cell Science. PMID 30709920 DOI: 10.1242/jcs.229500  0.52
2019 Bunton-Stasyshyn RKA, Wagnon JL, Wengert ER, Barker BS, Faulkner A, Wagley PK, Bhatia K, Jones JM, Maniaci MR, Parent JM, Goodkin HP, Patel MK, Meisler MH. Prominent role of forebrain excitatory neurons in SCN8A encephalopathy. Brain : a Journal of Neurology. PMID 30601941 DOI: 10.1093/brain/awy324  0.32
2018 Mironova YA, Lin JP, Kalinski A, Huffman L, Lenk GM, Havton LA, Meisler MH, Giger RJ. Protective Role of the Lipid Phosphatase Fig4 in the Adult Nervous System. Human Molecular Genetics. PMID 29688489 DOI: 10.1093/hmg/ddy145  0.52
2016 Barker BS, Ottolini M, Wagnon JL, Hollander RM, Meisler MH, Patel MK. The SCN8A encephalopathy mutation p.Ile1327Val displays elevated sensitivity to the anticonvulsant phenytoin. Epilepsia. PMID 27375106 DOI: 10.1111/epi.13461  1
2016 Lenk GM, Szymanska K, Debska-Vielhaber G, Rydzanicz M, Walczak A, Bekiesinska-Figatowska M, Vielhaber S, Hallmann K, Stawinski P, Buehring S, Hsu DA, Kunz WS, Meisler MH, Ploski R. Biallelic Mutations of VAC14 in Pediatric-Onset Neurological Disease. American Journal of Human Genetics. PMID 27292112 DOI: 10.1016/j.ajhg.2016.05.008  1
2016 He F, Jones JM, Figueroa-Romero C, Zhang D, Feldman EL, Goutman SA, Meisler MH, Callaghan BC, Todd PK. Screening for novel hexanucleotide repeat expansions at ALS- and FTD-associated loci. Neurology. Genetics. 2: e71. PMID 27274540 DOI: 10.1212/NXG.0000000000000071  0.32
2016 Meisler MH, Helman G, Hammer MF, Fureman BE, Gaillard WD, Goldin AL, Hirose S, Ishii A, Kroner BL, Lossin C, Mefford HC, Parent JM, Patel M, Schreiber J, Stewart R, et al. SCN8A encephalopathy: Research progress and prospects. Epilepsia. PMID 27270488 DOI: 10.1111/epi.13422  1
2016 Mironova YA, Lenk GM, Lin JP, Lee SJ, Twiss JL, Vaccari I, Bolino A, Havton LA, Min SH, Abrams CS, Shrager P, Meisler MH, Giger RJ. PI(3,5)P2 biosynthesis regulates oligodendrocyte differentiation by intrinsic and extrinsic mechanisms. Elife. 5. PMID 27008179 DOI: 10.7554/eLife.13023  1
2016 Jones JM, Dionne L, Dell'Orco J, Parent R, Krueger JN, Cheng X, Dib-Hajj SD, Bunton-Stasyshyn RK, Sharkey LM, Dowling JJ, Murphy GG, Shakkottai VG, Shrager P, Meisler MH. Single amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Nav1.6) in a mouse mutant with a chronic movement disorder. Neurobiology of Disease. PMID 26807988 DOI: 10.1016/j.nbd.2016.01.018  1
2015 Lenk GM, Frei CM, Miller AC, Wallen RC, Mironova YA, Giger RJ, Meisler MH. Rescue of neurodegeneration in the Fig4 null mouse by a catalytically inactive FIG4 transgene. Human Molecular Genetics. PMID 26604144 DOI: 10.1093/hmg/ddv480  1
2015 Wu YW, Sullivan J, McDaniel SS, Meisler MH, Walsh EM, Li SX, Kuzniewicz MW. Incidence of Dravet Syndrome in a US Population. Pediatrics. PMID 26438699 DOI: 10.1542/peds.2015-1807  1
2015 Pal D, Jones JM, Wisidagamage S, Meisler MH, Mashour GA. Reduced Nav1.6 Sodium Channel Activity in Mice Increases In Vivo Sensitivity to Volatile Anesthetics. Plos One. 10: e0134960. PMID 26252017 DOI: 10.1371/journal.pone.0134960  1
2015 Wagnon JL, Meisler MH. Recurrent and Non-Recurrent Mutations of SCN8A in Epileptic Encephalopathy. Frontiers in Neurology. 6: 104. PMID 26029160 DOI: 10.3389/fneur.2015.00104  1
2015 Blanchard MG, Willemsen MH, Walker JB, Dib-Hajj SD, Waxman SG, Jongmans MC, Kleefstra T, van de Warrenburg BP, Praamstra P, Nicolai J, Yntema HG, Bindels RJ, Meisler MH, Kamsteeg EJ. De novo gain-of-function and loss-of-function mutations of SCN8A in patients with intellectual disabilities and epilepsy. Journal of Medical Genetics. 52: 330-7. PMID 25725044 DOI: 10.1136/jmedgenet-2014-102813  1
2015 Menezes MP, Waddell L, Lenk GM, Kaur S, MacArthur DG, Meisler MH, Clarke NF. Response. Neuromuscular Disorders : Nmd. 25: 360. PMID 25617004 DOI: 10.1016/j.nmd.2014.12.008  1
2015 Wagnon JL, Korn MJ, Parent R, Tarpey TA, Jones JM, Hammer MF, Murphy GG, Parent JM, Meisler MH. Convulsive seizures and SUDEP in a mouse model of SCN8A epileptic encephalopathy. Human Molecular Genetics. 24: 506-15. PMID 25227913 DOI: 10.1093/hmg/ddu470  1
2015 Vaccari I, Carbone A, Previtali SC, Mironova YA, Alberizzi V, Noseda R, Rivellini C, Bianchi F, Del Carro U, D'Antonio M, Lenk GM, Wrabetz L, Giger RJ, Meisler MH, Bolino A. Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy. Human Molecular Genetics. 24: 383-96. PMID 25187576 DOI: 10.1093/hmg/ddu451  1
2014 de Kovel CG, Meisler MH, Brilstra EH, van Berkestijn FM, van 't Slot R, van Lieshout S, Nijman IJ, O'Brien JE, Hammer MF, Estacion M, Waxman SG, Dib-Hajj SD, Koeleman BP. Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy. Epilepsy Research. 108: 1511-8. PMID 25239001 DOI: 10.1016/j.eplepsyres.2014.08.020  1
2014 Menezes MP, Waddell L, Lenk GM, Kaur S, MacArthur DG, Meisler MH, Clarke NF. Whole exome sequencing identifies three recessive FIG4 mutations in an apparently dominant pedigree with Charcot-Marie-Tooth disease. Neuromuscular Disorders : Nmd. 24: 666-70. PMID 24878229 DOI: 10.1016/j.nmd.2014.04.010  1
2014 Estacion M, O'Brien JE, Conravey A, Hammer MF, Waxman SG, Dib-Hajj SD, Meisler MH. A novel de novo mutation of SCN8A (Nav1.6) with enhanced channel activation in a child with epileptic encephalopathy. Neurobiology of Disease. 69: 117-23. PMID 24874546 DOI: 10.1016/j.nbd.2014.05.017  1
2014 Baulac S, Lenk GM, Dufresnois B, Ouled Amar Bencheikh B, Couarch P, Renard J, Larson PA, Ferguson CJ, Noé E, Poirier K, Hubans C, Ferreira S, Guerrini R, Ouazzani R, El Hachimi KH, ... Meisler MH, et al. Role of the phosphoinositide phosphatase FIG4 gene in familial epilepsy with polymicrogyria. Neurology. 82: 1068-75. PMID 24598713 DOI: 10.1212/WNL.0000000000000241  1
2014 Lenk GM, Meisler MH. Mouse models of PI(3,5)P2 deficiency with impaired lysosome function. Methods in Enzymology. 534: 245-60. PMID 24359958 DOI: 10.1016/B978-0-12-397926-1.00014-7  1
2014 Jones JM, Meisler MH. Modeling human epilepsy by TALEN targeting of mouse sodium channel Scn8a. Genesis (New York, N.Y. : 2000). 52: 141-8. PMID 24288358 DOI: 10.1002/dvg.22731  1
2013 Auerbach DS, Jones J, Clawson BC, Offord J, Lenk GM, Ogiwara I, Yamakawa K, Meisler MH, Parent JM, Isom LL. Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome. Plos One. 8: e77843. PMID 24155976 DOI: 10.1371/journal.pone.0077843  1
2013 Reifler A, Lenk GM, Li X, Groom L, Brooks SV, Wilson D, Bowerson M, Dirksen RT, Meisler MH, Dowling JJ. Murine Fig4 is dispensable for muscle development but required for muscle function. Skeletal Muscle. 3: 21. PMID 24004519 DOI: 10.1186/2044-5040-3-21  1
2013 Liu Y, Lopez-Santiago LF, Yuan Y, Jones JM, Zhang H, O'Malley HA, Patino GA, O'Brien JE, Rusconi R, Gupta A, Thompson RC, Natowicz MR, Meisler MH, Isom LL, Parent JM. Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism. Annals of Neurology. 74: 128-39. PMID 23821540 DOI: 10.1002/ana.23897  1
2013 Campeau PM, Lenk GM, Lu JT, Bae Y, Burrage L, Turnpenny P, Román Corona-Rivera J, Morandi L, Mora M, Reutter H, Vulto-van Silfhout AT, Faivre L, Haan E, Gibbs RA, Meisler MH, et al. Yunis-Varón syndrome is caused by mutations in FIG4, encoding a phosphoinositide phosphatase. American Journal of Human Genetics. 92: 781-91. PMID 23623387 DOI: 10.1016/j.ajhg.2013.03.020  1
2013 Meisler MH, Grant AE, Jones JM, Lenk GM, He F, Todd PK, Kamali M, Albin RL, Lieberman AP, Langenecker SA, McInnis MG. C9ORF72 expansion in a family with bipolar disorder. Bipolar Disorders. 15: 326-32. PMID 23551834 DOI: 10.1111/bdi.12063  1
2012 Zolov SN, Bridges D, Zhang Y, Lee WW, Riehle E, Verma R, Lenk GM, Converso-Baran K, Weide T, Albin RL, Saltiel AR, Meisler MH, Russell MW, Weisman LS. In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P. Proceedings of the National Academy of Sciences of the United States of America. 109: 17472-7. PMID 23047693 DOI: 10.1073/pnas.1203106109  1
2012 Zhang Y, McCartney AJ, Zolov SN, Ferguson CJ, Meisler MH, Sutton MA, Weisman LS. Modulation of synaptic function by VAC14, a protein that regulates the phosphoinositides PI(3,5)Pâ‚‚ and PI(5)P. The Embo Journal. 31: 3442-56. PMID 22842785 DOI: 10.1038/emboj.2012.200  1
2012 Need AC, Shashi V, Hitomi Y, Schoch K, Shianna KV, McDonald MT, Meisler MH, Goldstein DB. Clinical application of exome sequencing in undiagnosed genetic conditions. Journal of Medical Genetics. 49: 353-61. PMID 22581936 DOI: 10.1136/jmedgenet-2012-100819  1
2012 Ferguson CJ, Lenk GM, Jones JM, Grant AE, Winters JJ, Dowling JJ, Giger RJ, Meisler MH. Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration. Human Molecular Genetics. 21: 3525-34. PMID 22581779 DOI: 10.1093/hmg/dds179  1
2012 O'Brien JE, Sharkey LM, Vallianatos CN, Han C, Blossom JC, Yu T, Waxman SG, Dib-Hajj SD, Meisler MH. Interaction of voltage-gated sodium channel Nav1.6 (SCN8A) with microtubule-associated protein Map1b. The Journal of Biological Chemistry. 287: 18459-66. PMID 22474336 DOI: 10.1074/jbc.M111.336024  1
2012 Veeramah KR, O'Brien JE, Meisler MH, Cheng X, Dib-Hajj SD, Waxman SG, Talwar D, Girirajan S, Eichler EE, Restifo LL, Erickson RP, Hammer MF. De novo pathogenic SCN8A mutation identified by whole-genome sequencing of a family quartet affected by infantile epileptic encephalopathy and SUDEP. American Journal of Human Genetics. 90: 502-10. PMID 22365152 DOI: 10.1016/j.ajhg.2012.01.006  1
2012 Gehman LT, Meera P, Stoilov P, Shiue L, O'Brien JE, Meisler MH, Ares M, Otis TS, Black DL. The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function. Genes & Development. 26: 445-60. PMID 22357600 DOI: 10.1101/gad.182477.111  1
2012 O'Brien JE, Drews VL, Jones JM, Dugas JC, Barres BA, Meisler MH. Rbfox proteins regulate alternative splicing of neuronal sodium channel SCN8A. Molecular and Cellular Neurosciences. 49: 120-6. PMID 22044765 DOI: 10.1016/j.mcn.2011.10.005  1
2012 Noujaim SF, Kaur K, Milstein M, Jones JM, Furspan P, Jiang D, Auerbach DS, Herron T, Meisler MH, Jalife J. A null mutation of the neuronal sodium channel NaV1.6 disrupts action potential propagation and excitation-contraction coupling in the mouse heart. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 63-72. PMID 21948246 DOI: 10.1096/fj.10-179770  1
2011 Winters JJ, Ferguson CJ, Lenk GM, Giger-Mateeva VI, Shrager P, Meisler MH, Giger RJ. Congenital CNS hypomyelination in the Fig4 null mouse is rescued by neuronal expression of the PI(3,5)P(2) phosphatase Fig4. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17736-51. PMID 22131434 DOI: 10.1523/JNEUROSCI.1482-11.2011  1
2011 Vaccari I, Dina G, Tronchère H, Kaufman E, Chicanne G, Cerri F, Wrabetz L, Payrastre B, Quattrini A, Weisman LS, Meisler MH, Bolino A. Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies. Plos Genetics. 7: e1002319. PMID 22028665 DOI: 10.1371/journal.pgen.1002319  1
2011 Nicholson G, Lenk GM, Reddel SW, Grant AE, Towne CF, Ferguson CJ, Simpson E, Scheuerle A, Yasick M, Hoffman S, Blouin R, Brandt C, Coppola G, Biesecker LG, Batish SD, ... Meisler MH, et al. Distinctive genetic and clinical features of CMT4J: a severe neuropathy caused by mutations in the PI(3,5)Pâ‚‚ phosphatase FIG4. Brain : a Journal of Neurology. 134: 1959-71. PMID 21705420 DOI: 10.1093/brain/awr148  1
2011 Lenk GM, Ferguson CJ, Chow CY, Jin N, Jones JM, Grant AE, Zolov SN, Winters JJ, Giger RJ, Dowling JJ, Weisman LS, Meisler MH. Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J. Plos Genetics. 7: e1002104. PMID 21655088 DOI: 10.1371/journal.pgen.1002104  1
2011 Freilich ER, Jones JM, Gaillard WD, Conry JA, Tsuchida TN, Reyes C, Dib-Hajj S, Waxman SG, Meisler MH, Pearl PL. Novel SCN1A mutation in a proband with malignant migrating partial seizures of infancy. Archives of Neurology. 68: 665-71. PMID 21555645 DOI: 10.1001/archneurol.2011.98  1
2010 Meisler MH, O'Brien JE, Sharkey LM. Sodium channel gene family: epilepsy mutations, gene interactions and modifier effects. The Journal of Physiology. 588: 1841-8. PMID 20351042 DOI: 10.1113/jphysiol.2010.188482  1
2010 Osorio N, Cathala L, Meisler MH, Crest M, Magistretti J, Delmas P. Persistent Nav1.6 current at axon initial segments tunes spike timing of cerebellar granule cells. The Journal of Physiology. 588: 651-70. PMID 20173079 DOI: 10.1113/jphysiol.2010.183798  1
2010 Martin MS, Dutt K, Papale LA, Dubé CM, Dutton SB, de Haan G, Shankar A, Tufik S, Meisler MH, Baram TZ, Goldin AL, Escayg A. Altered function of the SCN1A voltage-gated sodium channel leads to gamma-aminobutyric acid-ergic (GABAergic) interneuron abnormalities. The Journal of Biological Chemistry. 285: 9823-34. PMID 20100831 DOI: 10.1074/jbc.M109.078568  1
2010 Ferguson CJ, Lenk GM, Meisler MH. PtdIns(3,5)P2 and autophagy in mouse models of neurodegeneration. Autophagy. 6: 170-1. PMID 20009544 DOI: 10.4161/auto.6.1.10626  1
2010 Meisler MH. Gene interactions and modifiers in epilepsy Epilepsia. 51: 66. DOI: 10.1111/j.1528-1167.2010.02852.x  1
2009 Ferguson CJ, Lenk GM, Meisler MH. Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2. Human Molecular Genetics. 18: 4868-78. PMID 19793721 DOI: 10.1093/hmg/ddp460  1
2009 Sharkey LM, Cheng X, Drews V, Buchner DA, Jones JM, Justice MJ, Waxman SG, Dib-Hajj SD, Meisler MH. The ataxia3 mutation in the N-terminal cytoplasmic domain of sodium channel Na(v)1.6 disrupts intracellular trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2733-41. PMID 19261867 DOI: 10.1523/JNEUROSCI.6026-08.2009  1
2009 Papale LA, Beyer B, Jones JM, Sharkey LM, Tufik S, Epstein M, Letts VA, Meisler MH, Frankel WN, Escayg A. Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice. Human Molecular Genetics. 18: 1633-41. PMID 19254928 DOI: 10.1093/hmg/ddp081  1
2009 Chow CY, Landers JE, Bergren SK, Sapp PC, Grant AE, Jones JM, Everett L, Lenk GM, McKenna-Yasek DM, Weisman LS, Figlewicz D, Brown RH, Meisler MH. Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS. American Journal of Human Genetics. 84: 85-8. PMID 19118816 DOI: 10.1016/j.ajhg.2008.12.010  1
2009 Mastroiacovo F, Busceti CL, Biagioni F, Moyanova SG, Meisler MH, Battaglia G, Caricasole A, Bruno V, Nicoletti F. Induction of the Wnt antagonist, Dickkopf-1, contributes to the development of neuronal death in models of brain focal ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 264-76. PMID 18827832 DOI: 10.1038/jcbfm.2008.111  1
2009 Sharkey LM, Jones JM, Hedera P, Meisler MH. Evaluation of SCN8A as a candidate gene for autosomal dominant essential tremor. Parkinsonism & Related Disorders. 15: 321-3. PMID 18718804 DOI: 10.1016/j.parkreldis.2008.06.010  1
2008 Jin N, Chow CY, Liu L, Zolov SN, Bronson R, Davisson M, Petersen JL, Zhang Y, Park S, Duex JE, Goldowitz D, Meisler MH, Weisman LS. VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse. The Embo Journal. 27: 3221-34. PMID 19037259 DOI: 10.1038/emboj.2008.248  1
2008 Catterall WA, Dib-Hajj S, Meisler MH, Pietrobon D. Inherited neuronal ion channelopathies: new windows on complex neurological diseases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11768-77. PMID 19005038 DOI: 10.1523/JNEUROSCI.3901-08.2008  1
2008 Howell VM, de Haan G, Bergren S, Jones JM, Culiat CT, Michaud EJ, Frankel WN, Meisler MH. A targeted deleterious allele of the splicing factor SCNM1 in the mouse. Genetics. 180: 1419-27. PMID 18791226 DOI: 10.1534/genetics.108.094227  1
2008 Meisler MH, Russ C, Montgomery KT, Greenway M, Ennis S, Hardiman O, Figlewicz DA, Quenneville NR, Conibear E, Brown RH. Evaluation of the Golgi trafficking protein VPS54 (wobbler) as a candidate for ALS. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 9: 141-8. PMID 18574757 DOI: 10.1080/17482960801934403  1
2008 Zhang X, Chow CY, Sahenk Z, Shy ME, Meisler MH, Li J. Mutation of FIG4 causes a rapidly progressive, asymmetric neuronal degeneration. Brain : a Journal of Neurology. 131: 1990-2001. PMID 18556664 DOI: 10.1093/brain/awn114  1
2008 McKinney BC, Chow CY, Meisler MH, Murphy GG. Exaggerated emotional behavior in mice heterozygous null for the sodium channel Scn8a (Nav1.6). Genes, Brain, and Behavior. 7: 629-38. PMID 18363861 DOI: 10.1111/j.1601-183X.2008.00399.x  1
2008 Holland KD, Kearney JA, Glauser TA, Buck G, Keddache M, Blankston JR, Glaaser IW, Kass RS, Meisler MH. Mutation of sodium channel SCN3A in a patient with cryptogenic pediatric partial epilepsy. Neuroscience Letters. 433: 65-70. PMID 18242854 DOI: 10.1016/j.neulet.2007.12.064  1
2007 Zhang Y, Zolov SN, Chow CY, Slutsky SG, Richardson SC, Piper RC, Yang B, Nau JJ, Westrick RJ, Morrison SJ, Meisler MH, Weisman LS. Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 17518-23. PMID 17956977 DOI: 10.1073/pnas.0702275104  1
2007 Drews VL, Shi K, de Haan G, Meisler MH. Identification of evolutionarily conserved, functional noncoding elements in the promoter region of the sodium channel gene SCN8A. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 723-31. PMID 17924165 DOI: 10.1007/s00335-007-9059-8  1
2007 Howell VM, Jones JM, Bergren SK, Li L, Billi AC, Avenarius MR, Meisler MH. Evidence for a direct role of the disease modifier SCNM1 in splicing. Human Molecular Genetics. 16: 2506-16. PMID 17656373 DOI: 10.1093/hmg/ddm206  1
2007 Chow CY, Zhang Y, Dowling JJ, Jin N, Adamska M, Shiga K, Szigeti K, Shy ME, Li J, Zhang X, Lupski JR, Weisman LS, Meisler MH. Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J. Nature. 448: 68-72. PMID 17572665 DOI: 10.1038/nature05876  1
2006 Meisler MH, Trudeau MM, Dalton JC, Day JW, Ranum LP. Gene symbol: SCN8A. Disease: Ataxia. Accession #Hd0520. Human Genetics. 118: 776. PMID 17297687  1
2006 Holland KD, Fleming MT, Cheek S, Moran JL, Beier DR, Meisler MH. De novo exon duplication in a new allele of mouse Glra1 (spasmodic). Genetics. 174: 2245-7. PMID 17028313 DOI: 10.1534/genetics.106.065532  1
2006 Woodruff-Pak DS, Green JT, Levin SI, Meisler MH. Inactivation of sodium channel Scn8A (Na-sub(v)1.6) in Purkinje neurons impairs learning in Morris water maze and delay but not trace eyeblink classical conditioning. Behavioral Neuroscience. 120: 229-40. PMID 16719687 DOI: 10.1037/0735-7044.120.2.229  1
2006 Levin SI, Khaliq ZM, Aman TK, Grieco TM, Kearney JA, Raman IM, Meisler MH. Impaired motor function in mice with cell-specific knockout of sodium channel Scn8a (NaV1.6) in cerebellar purkinje neurons and granule cells. Journal of Neurophysiology. 96: 785-93. PMID 16687615 DOI: 10.1152/jn.01193.2005  1
2006 Kearney JA, Wiste AK, Stephani U, Trudeau MM, Siegel A, RamachandranNair R, Elterman RD, Muhle H, Reinsdorf J, Shields WD, Meisler MH, Escayg A. Recurrent de novo mutations of SCN1A in severe myoclonic epilepsy of infancy. Pediatric Neurology. 34: 116-20. PMID 16458823 DOI: 10.1016/j.pediatrneurol.2005.07.009  1
2006 Trudeau MM, Dalton JC, Day JW, Ranum LP, Meisler MH. Heterozygosity for a protein truncation mutation of sodium channel SCN8A in a patient with cerebellar atrophy, ataxia, and mental retardation. Journal of Medical Genetics. 43: 527-30. PMID 16236810 DOI: 10.1136/jmg.2005.035667  1
2005 Schmitt-John T, Drepper C, Mussmann A, Hahn P, Kuhlmann M, Thiel C, Hafner M, Lengeling A, Heimann P, Jones JM, Meisler MH, Jockusch H. Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse. Nature Genetics. 37: 1213-5. PMID 16244655 DOI: 10.1038/ng1661  1
2005 Meisler MH, Kearney JA. Sodium channel mutations in epilepsy and other neurological disorders. The Journal of Clinical Investigation. 115: 2010-7. PMID 16075041 DOI: 10.1172/JCI25466  1
2005 Turnbull J, Lohi H, Kearney JA, Rouleau GA, Delgado-Escueta AV, Meisler MH, Cossette P, Minassian BA. Sacred disease secrets revealed: the genetics of human epilepsy. Human Molecular Genetics. 14: 2491-500. PMID 16049035 DOI: 10.1093/hmg/ddi250  1
2005 Adamska M, Billi AC, Cheek S, Meisler MH. Genetic interaction between Wnt7a and Lrp6 during patterning of dorsal and posterior structures of the mouse limb. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 233: 368-72. PMID 15880584 DOI: 10.1002/dvdy.20437  1
2005 Drews VL, Lieberman AP, Meisler MH. Multiple transcripts of sodium channel SCN8A (Na(V)1.6) with alternative 5'- and 3'-untranslated regions and initial characterization of the SCN8A promoter. Genomics. 85: 245-57. PMID 15676283 DOI: 10.1016/j.ygeno.2004.09.002  1
2004 Meisler MH, Plummer NW, Burgess DL, Buchner DA, Sprunger LK. Allelic mutations of the sodium channel SCN8A reveal multiple cellular and physiological functions. Genetica. 122: 37-45. PMID 15619959 DOI: 10.1007/s10709-004-1441-9  1
2004 Spampanato J, Kearney JA, de Haan G, McEwen DP, Escayg A, Aradi I, MacDonald BT, Levin SI, Soltesz I, Benna P, Montalenti E, Isom LL, Goldin AL, Meisler MH. A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for beta subunit interaction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10022-34. PMID 15525788 DOI: 10.1523/JNEUROSCI.2034-04.2004  1
2004 Gupta S, Singh R, Datta P, Zhang Z, Orr C, Lu Z, Dubois G, Zervos AS, Meisler MH, Srinivasula SM, Fernandes-Alnemri T, Alnemri ES. The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity. The Journal of Biological Chemistry. 279: 45844-54. PMID 15294909 DOI: 10.1074/jbc.M404940200  1
2004 Levin SI, Meisler MH. Floxed allele for conditional inactivation of the voltage-gated sodium channel Scn8a (NaV1.6). Genesis (New York, N.Y. : 2000). 39: 234-9. PMID 15286995 DOI: 10.1002/gene.20050  1
2004 Adamska M, MacDonald BT, Sarmast ZH, Oliver ER, Meisler MH. En1 and Wnt7a interact with Dkk1 during limb development in the mouse. Developmental Biology. 272: 134-44. PMID 15242796 DOI: 10.1016/j.ydbio.2004.04.026  1
2004 Buchner DA, Seburn KL, Frankel WN, Meisler MH. Three ENU-induced neurological mutations in the pore loop of sodium channel Scn8a (Na(v)1.6) and a genetically linked retinal mutation, rd13. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 344-51. PMID 15170223 DOI: 10.1007/s00335-004-2332-1  1
2004 MacDonald BT, Adamska M, Meisler MH. Hypomorphic expression of Dkk1 in the doubleridge mouse: dose dependence and compensatory interactions with Lrp6. Development (Cambridge, England). 131: 2543-52. PMID 15115753 DOI: 10.1242/dev.01126  1
2003 Hamann M, Meisler MH, Richter A. Motor disturbances in mice with deficiency of the sodium channel gene Scn8a show features of human dystonia. Experimental Neurology. 184: 830-8. PMID 14769375 DOI: 10.1016/S0014-4886(03)00290-5  1
2003 Jones JM, Datta P, Srinivasula SM, Ji W, Gupta S, Zhang Z, Davies E, Hajnóczky G, Saunders TL, Van Keuren ML, Fernandes-Alnemri T, Meisler MH, Alnemri ES. Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice. Nature. 425: 721-7. PMID 14534547 DOI: 10.1038/nature02052  1
2003 Buchner DA, Trudeau M, George AL, Sprunger LK, Meisler MH. High-resolution mapping of the sodium channel modifier Scnm1 on mouse chromosome 3 and identification of a 1.3-kb recombination hot spot. Genomics. 82: 452-9. PMID 13679025 DOI: 10.1016/S0888-7543(03)00152-6  1
2003 Buchner DA, Trudeau M, Meisler MH. SCNM1, a putative RNA splicing factor that modifies disease severity in mice. Science (New York, N.Y.). 301: 967-9. PMID 12920299 DOI: 10.1126/science.1086187  1
2003 Wang Y, Matsuda S, Drews V, Torashima T, Meisler MH, Yuzaki M. A hot spot for hotfoot mutations in the gene encoding the delta2 glutamate receptor. The European Journal of Neuroscience. 17: 1581-90. PMID 12752376 DOI: 10.1046/j.1460-9568.2003.02595.x  1
2003 Buchner DA, Meisler MH. TSRC1, a widely expressed gene containing seven thrombospondin type I repeats. Gene. 307: 23-30. PMID 12706885 DOI: 10.1016/S0378-1119(03)00423-2  1
2003 Adamska M, MacDonald BT, Meisler MH. Doubleridge, a mouse mutant with defective compaction of the apical ectodermal ridge and normal dorsal-ventral patterning of the limb. Developmental Biology. 255: 350-62. PMID 12648495 DOI: 10.1016/S0012-1606(02)00114-8  1
2003 Weiss LA, Escayg A, Kearney JA, Trudeau M, MacDonald BT, Mori M, Reichert J, Buxbaum JD, Meisler MH. Sodium channels SCN1A, SCN2A and SCN3A in familial autism. Molecular Psychiatry. 8: 186-94. PMID 12610651 DOI: 10.1038/sj.mp.4001241  1
2003 Spampanato J, Escayg A, Meisler MH, Goldin AL. Generalized epilepsy with febrile seizures plus type 2 mutation W1204R alters voltage-dependent gating of Na(v)1.1 sodium channels. Neuroscience. 116: 37-48. PMID 12535936 DOI: 10.1016/S0306-4522(02)00698-X  1
2002 Kearney JA, Buchner DA, De Haan G, Adamska M, Levin SI, Furay AR, Albin RL, Jones JM, Montal M, Stevens MJ, Sprunger LK, Meisler MH. Molecular and pathological effects of a modifier gene on deficiency of the sodium channel Scn8a (Na(v)1.6). Human Molecular Genetics. 11: 2765-75. PMID 12374766  1
2002 Rathke-Hartlieb S, Schlomann U, Heimann P, Meisler MH, Jockusch H, Bartsch JW. Progressive loss of striatal neurons causes motor dysfunction in MND2 mutant mice and is not prevented by Bcl-2. Experimental Neurology. 175: 87-97. PMID 12009762 DOI: 10.1006/exnr.2002.7868  1
2002 Meisler MH, Kearney JA, Sprunger LK, MacDonald BT, Buchner DA, Escayg A. Mutations of voltage-gated sodium channels in movement disorders and epilepsy. Novartis Foundation Symposium. 241: 72-81; discussion 82. PMID 11771652  1
2001 Meisler MH, Kearney J, Ottman R, Escayg A. Identification of epilepsy genes in human and mouse. Annual Review of Genetics. 35: 567-88. PMID 11700294 DOI: 10.1146/annurev.genet.35.102401.091142  1
2001 Meisler MH. Evolutionarily conserved noncoding DNA in the human genome: How much and what for? Genome Research. 11: 1617-1618. PMID 11591637 DOI: 10.1101/gr.211401  1
2001 Spampanato J, Escayg A, Meisler MH, Goldin AL. Functional effects of two voltage-gated sodium channel mutations that cause generalized epilepsy with febrile seizures plus type 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7481-90. PMID 11567038  1
2001 Meisler MH, Kearney J, Escayg A, MacDonald BT, Sprunger LK. Sodium channels and neurological disease: insights from Scn8a mutations in the mouse. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 7: 136-45. PMID 11496924  1
2001 Ji W, Chen F, Do T, Do A, Roe BA, Meisler MH. DQX1, an RNA-dependent ATPase homolog with a novel DEAQ box: expression pattern and genomic sequence comparison of the human and mouse genes. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 12: 456-61. PMID 11353393 DOI: 10.1007/s003350020032  1
2001 Reid E, Escayg A, Dearlove AM, Lee DD, Meisler MH, Rubinsztein DC. The spastic paraplegia SPG10 locus: Narrowing of critical region and exclusion of sodium channel gene SCN8A as a candidate [7] Journal of Medical Genetics. 38: 65-67. PMID 11334010  1
2001 Escayg A, Heils A, MacDonald BT, Haug K, Sander T, Meisler MH. A novel SCN1A mutation associated with generalized epilepsy with febrile seizures plus--and prevalence of variants in patients with epilepsy. American Journal of Human Genetics. 68: 866-73. PMID 11254445 DOI: 10.1086/319524  1
2001 Kearney JA, Plummer NW, Smith MR, Kapur J, Cummins TR, Waxman SG, Goldin AL, Meisler MH. A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities. Neuroscience. 102: 307-17. PMID 11166117 DOI: 10.1016/S0306-4522(00)00479-6  1
2000 Goldin AL, Barchi RL, Caldwell JH, Hofmann F, Howe JR, Hunter JC, Kallen RG, Mandel G, Meisler MH, Netter YB, Noda M, Tamkun MM, Waxman SG, Wood JN, Catterall WA. Nomenclature of voltage-gated sodium channels. Neuron. 28: 365-8. PMID 11144347  1
2000 Escayg A, De Waard M, Lee DD, Bichet D, Wolf P, Mayer T, Johnston J, Baloh R, Sander T, Meisler MH. Coding and noncoding variation of the human calcium-channel beta4-subunit gene CACNB4 in patients with idiopathic generalized epilepsy and episodic ataxia. American Journal of Human Genetics. 66: 1531-9. PMID 10762541 DOI: 10.1086/302909  1
2000 Jones JM, Huang JD, Mermall V, Hamilton BA, Mooseker MS, Escayg A, Copeland NG, Jenkins NA, Meisler MH. The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5a. Human Molecular Genetics. 9: 821-8. PMID 10749990  1
2000 Escayg A, MacDonald BT, Meisler MH, Baulac S, Huberfeld G, An-Gourfinkel I, Brice A, LeGuern E, Moulard B, Chaigne D, Buresi C, Malafosse A. Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2. Nature Genetics. 24: 343-5. PMID 10742094 DOI: 10.1038/74159  1
2000 Sprunger LK, Meisler MH, Stratakis CA. Recombination between the sodium channel SCN8A and the Allgrove syndrome gene in a Puerto Rican kindred Journal of Endocrine Genetics. 1: 165-169.  1
1999 Griffith AJ, Ji W, Prince ME, Altschuler RA, Meisler MH. Optic, olfactory, and vestibular dysmorphogenesis in the homozygous mouse insertional mutant Tg9257. Journal of Craniofacial Genetics and Developmental Biology. 19: 157-63. PMID 10589397  1
1999 Chen K, Sprunger LK, Meisler MH, Waller HJ, Godfrey DA. Reduced spontaneous activity in the dorsal cochlear nucleus of Scn8a mutant mice. Brain Research. 847: 85-9. PMID 10564739 DOI: 10.1016/S0006-8993(99)02031-4  1
1999 Lu W, Phillips CL, Killen PD, Hlaing T, Harrison WR, Elder FF, Miner JH, Overbeek PA, Meisler MH. Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome. Genomics. 61: 113-24. PMID 10534397 DOI: 10.1006/geno.1999.5943  1
1999 Dib-Hajj SD, Tyrrell L, Escayg A, Wood PM, Meisler MH, Waxman SG. Coding sequence, genomic organization, and conserved chromosomal localization of the mouse gene Scn11a encoding the sodium channel NaN Genomics. 59: 309-318. PMID 10444332 DOI: 10.1006/geno.1999.5890  1
1999 Plummer NW, Meisler MH. Evolution and diversity of mammalian sodium channel genes Genomics. 57: 323-331. PMID 10198179 DOI: 10.1006/geno.1998.5735  1
1999 Ji W, Herron B, Jones JM, Jenkins NA, Gilbert DJ, Copeland NG, Swank R, Flaherty L, Meisler MH. Identification of genes within the Krd deletion on mouse chromosome 19. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 10: 399-401. PMID 10087301 DOI: 10.1007/s003359901010  1
1999 Sprunger LK, Escayg A, Tallaksen-Greene S, Albin RL, Meisler MH. Dystonia associated with mutation of the neuronal sodium channel Scn8a and identification of the modifier locus Scnm1 on mouse chromosome 3. Human Molecular Genetics. 8: 471-9. PMID 9949206  1
1999 Jang W, Hua A, Spilson SV, Miller W, Roe BA, Meisler MH. Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13. Genome Research. 9: 53-61. PMID 9927484  1
1998 Plummer NW, Galt J, Jones JM, Burgess DL, Sprunger LK, Kohrman DC, Meisler MH. Exon organization, coding sequence, physical mapping, and polymorphic intragenic markers for the human neuronal sodium channel gene SCN8A. Genomics. 54: 287-96. PMID 9828131 DOI: 10.1006/geno.1998.5550  1
1998 Weber JS, Jang W, Simin K, Lu W, Yu J, Meisler MH. High-resolution genetic, physical, and transcript map of the mnd2 region of mouse chromosome 6. Genomics. 54: 107-15. PMID 9806835 DOI: 10.1006/geno.1998.5496  1
1998 Smith MR, Smith RD, Plummer NW, Meisler MH, Goldin AL. Functional analysis of the mouse Scn8a sodium channel. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6093-102. PMID 9698304  1
1998 García KD, Sprunger LK, Meisler MH, Beam KG. The sodium channel Scn8a is the major contributor to the postnatal developmental increase of sodium current density in spinal motoneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5234-9. PMID 9651206  1
1998 Escayg A, Jones JM, Kearney JA, Hitchcock PF, Meisler MH. Calcium channel beta 4 (CACNB4): human ortholog of the mouse epilepsy gene lethargic. Genomics. 50: 14-22. PMID 9628818 DOI: 10.1006/geno.1998.5311  1
1998 Meisler MH, Griffith AJ, Warman M, Tiller G, Sprunger LK. Gene symbol: COL11A1. Disease: Marshall syndrome. Human Genetics. 102: 498. PMID 9600252  1
1998 Griffith AJ, Sprunger LK, Sirko-Osadsa DA, Tiller GE, Meisler MH, Warman ML. Marshall syndrome associated with a splicing defect at the COL11A1 locus. American Journal of Human Genetics. 62: 816-23. PMID 9529347 DOI: 10.1086/301789  1
1998 Jones JM, Bentley E, Meisler MH, Darling SM. Genetic mapping of the voltage-gated shaker potassium channel beta subunit Kcnab1 to mouse chromosome 3. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 260. PMID 9501317 DOI: 10.1007/s003359900740  1
1997 Meisler MH, Sprunger LK, Plummer NW, Escayg A, Jones JM. Ion channel mutations in mouse models of inherited neurological disease. Annals of Medicine. 29: 569-74. PMID 9562526  1
1997 Raman IM, Sprunger LK, Meisler MH, Bean BP. Altered subthreshold sodium currents and disrupted firing patterns in Purkinje neurons of Scn8a mutant mice. Neuron. 19: 881-91. PMID 9354334 DOI: 10.1016/S0896-6273(00)80969-1  1
1997 Meisler MH. Mutation watch: Mouse brachyury (T), the T-box gene family, and human disease Mammalian Genome. 8: 799-800. PMID 9337389 DOI: 10.1007/s003359900581  1
1997 Plummer NW, McBurney MW, Meisler MH. Alternative splicing of the sodium channel SCN8A predicts a truncated two-domain protein in fetal brain and non-neuronal cells Journal of Biological Chemistry. 272: 24008-24015. PMID 9295353 DOI: 10.1074/jbc.272.38.24008  1
1997 Camper SA, Meisler MH. Meeting report: 10th International Mouse Genome Conference Mammalian Genome. 8: 461-463. PMID 9195987 DOI: 10.1007/s003359900476  1
1997 Urbánek P, Fetka I, Meisler MH, Busslinger M. Cooperation of Pax2 and Pax5 in midbrain and cerebellum development Proceedings of the National Academy of Sciences of the United States of America. 94: 5703-5708. PMID 9159136 DOI: 10.1073/pnas.94.11.5703  1
1997 Jang W, Weber JS, Harkins EB, Meisler MH. Localization of the rhotekin gene RTKN on the physical maps of mouse chromosome 6 and human chromosome 2p13 and exclusion as a candidate for mnd2 and LGMD2BA Genomics. 40: 506-507. PMID 9073523 DOI: 10.1006/geno.1996.4593  1
1997 Jang W, Weber JS, Tokito MK, Holzbaur EL, Meisler MH. Mouse p150Glued (dynactin 1) cDNA sequence and evaluation as a candidate for the neuromuscular disease mutation mnd2. Biochemical and Biophysical Research Communications. 231: 344-7. PMID 9070275 DOI: 10.1006/bbrc.1997.6095  1
1997 Burgess DL, Jones JM, Meisler MH, Noebels JL. Mutation of the Ca2+ channel beta subunit gene Cchb4 is associated with ataxia and seizures in the lethargic (lh) mouse. Cell. 88: 385-92. PMID 9039265 DOI: 10.1016/S0092-8674(00)81877-2  1
1996 Scarpetta MA, Uhler MD, Meisler MH. The mouse Prkacn2 gene encoding protein kinase a inhibitor 2 is located on proximal Chromosome 10 Mammalian Genome. 7: 921-922. PMID 8995769  1
1996 Kohrman DC, Smith MR, Goldin AL, Harris J, Meisler MH. A missense mutation in the sodium channel Scn8a is responsible for cerebellar ataxia in the mouse mutant jolting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 5993-9. PMID 8815882  1
1996 Jang W, Weber JS, Bashir R, Bushby K, Meisler MH. Aup1, a novel gene on mouse Chromosome 6 and human chromosome 2p13 Genomics. 36: 366-368. PMID 8812468 DOI: 10.1006/geno.1996.0477  1
1996 Meisler MH. The role of the laboratory mouse in the human genome project American Journal of Human Genetics. 59: 764-771. PMID 8808590  1
1996 Griffith AJ, Burgess DL, Kohrman DC, Yu J, Blaschak J, Blanton SH, Boehnke M, Hecht JT, Overhauser J, Meisler MH. Localization of the homolog of a mouse craniofacial mutant to human chromosome 18q11 and evaluation of linkage to human CLP and CPO. Genomics. 34: 299-303. PMID 8786128 DOI: 10.1006/geno.1996.0290  1
1996 Jones JM, Ranscht B, Berglund EO, Gruenheid S, Gros P, Meisler MH. Close linkage of three neuronal genes on distal mouse chromosome 15. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 7: 696-7. PMID 8703126  1
1996 Burgess DL, Rafael JA, Meisler MH, Chamberlain JS. Dlgh1, a mouse homolog of the drosophila discs-large gene, is located on chromosome 16. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 7: 623-4. PMID 8678991  1
1996 Kohrman DC, Harris JB, Meisler MH. Mutation detection in the med and med(J) alleles of the sodium channel Scn8a: Unusual splicing due to a minor class AT-AC intron Journal of Biological Chemistry. 271: 17576-17581. PMID 8663325 DOI: 10.1074/jbc.271.29.17576  1
1996 Griffith AJ, Radice GL, Burgess DL, Kohrman DC, Hansen GM, Justice MJ, Johnson KR, Davisson MT, Meisler MH. Location of the 9257 and ataxia mutations on mouse chromosome 18. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 7: 417-9. PMID 8662222  1
1996 Jones JM, Meisler MH, Isom LL. Scn2b, a voltage-gated sodium channel beta2 gene on mouse chromosome 9. Genomics. 34: 258-9. PMID 8661062 DOI: 10.1006/geno.1996.0279  1
1995 Abel KJ, Xu J, Yin GY, Lyons RH, Meisler MH, Weber BL. Mouse Brca1: Localization, sequence analysis and identification of evolutionarily conserved domains Human Molecular Genetics. 4: 2265-2273. PMID 8634697 DOI: 10.1093/hmg/4.12.2265  1
1995 Patel A, Rochelle JM, Jones JM, Sumegi J, Uhl GR, Seldin MF, Meisler MH, Gregor P. Mapping of the taurine transporter gene to mouse chromosome 6 and to the short arm of human chromosome 3. Genomics. 25: 314-7. PMID 7774940 DOI: 10.1016/0888-7543(95)80146-D  1
1995 Jones JM, Popma SJ, Mizuta M, Seino S, Meisler MH. Synaptotagmin genes on mouse chromosomes 1, 7, and 10 and human chromosome 19. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 6: 212-3. PMID 7749232 DOI: 10.1007/BF00293017  1
1995 Burgess DL, Kohrman DC, Galt J, Plummer NW, Jones JM, Spear B, Meisler MH. Mutation of a new sodium channel gene, Scn8a, in the mouse mutant 'motor endplate disease'. Nature Genetics. 10: 461-5. PMID 7670495 DOI: 10.1038/ng0895-461  1
1995 Kohrman DC, Plummer NW, Schuster T, Jones JM, Jang W, Burgess DL, Galt J, Spear BT, Meisler MH. Insertional mutation of the motor endplate disease (med) locus on mouse chromosome 15. Genomics. 26: 171-7. PMID 7601440 DOI: 10.1016/0888-7543(95)80198-U  1
1994 Barrow LL, Simin K, Jones JM, Lee DC, Meisler MH. Conserved linkage of early growth response 4, annexin 4, and transforming growth factor alpha on mouse chromosome 6. Genomics. 19: 388-90. PMID 8188273 DOI: 10.1006/geno.1994.1078  1
1994 Swaroop A, Yang-feng TL, Liu W, Gieser L, Barrow LL, Chen KC, Agarwal N, Meisler MH, Smith DI. Molecular characterization of a novel human gene, SEC13R, related to the yeast secretory pathway gene SEC13, and mapping to a conserved linkage group on human chromosome 3p24-p25 and mouse chromosome 6 Human Molecular Genetics. 3: 1281-1286. PMID 7987303 DOI: 10.1093/hmg/3.8.1281  1
1994 Meisler MH, Barrow LL, Canessa CM, Rossier BC. SCNN1, an epithelial cell sodium channel gene in the conserved linkage group on mouse chromosome 6 and human chromosome 12. Genomics. 24: 185-6. PMID 7896277 DOI: 10.1006/geno.1994.1599  1
1994 Keller SA, Jones JM, Boyle A, Barrow LL, Killen PD, Green DG, Kapousta NV, Hitchcock PF, Swank RT, Meisler MH. Kidney and retinal defects (Krd), a transgene-induced mutation with a deletion of mouse chromosome 19 that includes the Pax2 locus. Genomics. 23: 309-20. PMID 7835879 DOI: 10.1006/geno.1994.1506  1
1994 Prins JB, Meisler MH, Seldin MF. Mouse chromosome 3 Mammalian Genome : Official Journal of the International Mammalian Genome Society. 5. PMID 7719016 DOI: 10.1007/BF00360829  1
1994 Ting CN, Kohrman D, Burgess DL, Boyle A, Altschuler RA, Gholizadeh G, Samuelson LC, Jang W, Meisler MH. Insertional mutation on mouse chromosome 18 with vestibular and craniofacial abnormalities. Genetics. 136: 247-54. PMID 7511123  1
1993 Bain PA, Meisler MH, Taylor BA, Payne AH. The genes encoding gonadal and nongonadal forms of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase are closely linked on mouse chromosome 3. Genomics. 16: 219-23. PMID 8486361 DOI: 10.1006/geno.1993.1162  1
1993 Yu H, Thun R, Chandrasekharappa S, Trent JM, Zhang J, Meisler MH. Human PCK1 Encoding Phosphoenolpyruvate Carboxykinase Is Located on Chromosome 20q13.2 Genomics. 15: 219-221. PMID 8432541 DOI: 10.1006/geno.1993.1040  1
1993 Ting CN, Burgess DL, Chamberlain JS, Keith TP, Falls K, Meisler MH. Phosphoenolpyruvate carboxykinase (GTP): characterization of the human PCK1 gene and localization distal to MODY on chromosome 20. Genomics. 16: 698-706. PMID 8325643 DOI: 10.1006/geno.1993.1250  1
1993 Jones JM, Albin RL, Feldman EL, Simin K, Schuster TG, Dunnick WA, Collins JT, Chrisp CE, Taylor BA, Meisler MH. mnd2: a new mouse model of inherited motor neuron disease. Genomics. 16: 669-77. PMID 8325640 DOI: 10.1006/geno.1993.1246  1
1993 Barrow LL, Simin K, Mohlke K, Nichols WC, Ginsburg D, Meisler MH. Conserved linkage of neurotrophin-3 and von Willebrand factor on mouse chromosome 6. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4: 343-5. PMID 8318738 DOI: 10.1007/BF00357095  1
1993 Jones JM, Elder JT, Simin K, Keller SA, Meisler MH. Insertional mutation of the hairless locus on mouse chromosome 14. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4: 639-43. PMID 8281013 DOI: 10.1007/BF00360900  1
1993 Seldin MF, Prins JB, Rodrigues NR, Todd JA, Meisler MH. Encyclopedia of the mouse genome III. October 1993. Mouse chromosome 3 Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4. PMID 8268684  1
1993 Bespalova IN, Farjo Q, Mortlock DP, Jackson AU, Meisler MH, Swaroop A, Burmeister M. Mapping of the neural retina leucine zipper gene, Nrl, to mouse chromosome 14. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4: 618-20. PMID 8268663 DOI: 10.1007/BF00361397  1
1993 Meisler MH, Ting CN. The remarkable evolutionary history of the human amylase genes Critical Reviews in Oral Biology and Medicine. 4: 503-509. PMID 7690604  1
1993 Johnson TM, Rosenberg MP, Meisler MH. An insulin-responsive element in the pancreatic enhancer of the amylase gene Journal of Biological Chemistry. 268: 464-468. PMID 7678001  1
1992 Meisler MH. Insertional mutation of 'classical' and novel genes in transgenic mice Trends in Genetics. 8: 341-344. PMID 1475845 DOI: 10.1016/0168-9525(92)90278-C  1
1992 Ting CN, Rosenberg MP, Snow CM, Samuelson LC, Meisler MH. Endogenous retroviral sequences are required for tissue-specific expression of a human salivary amylase gene Genes and Development. 6: 1457-1465. PMID 1379564  1
1992 Schmid RM, Meisler MH. Dietary regulation of pancreatic amylase in transgenic mice mediated by a 126-base pair DNA fragment American Journal of Physiology - Gastrointestinal and Liver Physiology. 262. PMID 1377451  1
1992 Jones JM, Meisler MH, Seldin MF, Lee BK, Eicher EM. Localization of insulin-2 (Ins-2) and the obesity mutant tubby (tub) to distinct regions of mouse chromosome 7 Genomics. 14: 197-199. PMID 1358794 DOI: 10.1016/S0888-7543(05)80308-8  1
1991 Samuelson LC, Wiebauer K, Howard G, Schmid RM, Koeplin D, Meisler MH. Isolation of the murine ribonuclease gene Rib-1: Structure and tissue specific expression of pancreas and parotid gland Nucleic Acids Research. 19: 6935-6941. PMID 1840677 DOI: 10.1093/nar/19.24.6935  1
1991 Wu KJ, Samuelson LC, Howard G, Meisler MH, Darlington GJ. Transactivation of pancreas-specific gene sequences in somatic cell hybrids Molecular and Cellular Biology. 11: 4423-4430. PMID 1715019  1
1991 Ceci JD, Kovatch RM, Swing DA, Jones JM, Snow CM, Rosenberg MP, Jenkins NA, Copeland NG, Meisler MH. Transgenic mice carrying a murine amylase 2.2/SV40 T antigen fusion gene develop pancreatic acinar cell and stomach carcinomas Oncogene. 6: 323-332. PMID 1705690  1
1990 Keller SA, Liptay S, Hajra A, Meisler MH. Transgene-induced mutation of the murine steel locus. Proceedings of the National Academy of Sciences of the United States of America. 87: 10019-22. PMID 1979872  1
1990 Keller SA, Rosenberg MP, Johnson TM, Howard G, Meisler MH. Regulation of amylase gene expression in diabetic mice is mediated by a cis-acting upstream element close to the pancreas-specific enhancer. Genes & Development. 4: 1316-21. PMID 1699843  1
1990 Johnson TM, Meisler MH, Bennett MI, Willsky GR. Vanadate induction of pancreatic amylase mRNA in diabetic rats Diabetes. 39: 757-759. PMID 1693346  1
1990 Samuelson LC, Wiebauer K, Snow CM, Meisler MH. Retroviral and Pseudogene Insertion Sites Reveal the Lineage of Human Salivary and Pancreatic Amylase Genes from a Single Gene during Primate Evolution Molecular and Cellular Biology. 10: 2513-2520. PMID 1692956  1
1990 Dracopoli NC, Meisler MH. Mapping the human amylase gene cluster on the proximal short arm of chromosome 1 using a highly informative (CA)n repeat Genomics. 7: 97-102. PMID 1692298 DOI: 10.1016/0888-7543(90)90523-W  1
1989 Grout PC, Mager WH, Frants RR, Meisler MH, Samuelson LC. The human amylase-encoding genes amy2 and amy3 are identical to AMY2A and AMY2B Gene. 85: 567-568. PMID 2483397 DOI: 10.1016/0378-1119(89)90454-X  1
1989 Howard G, Keller PR, Johnson TM, Meisler MH. Binding of a pancreatic nuclear protein is correlated with amytase enhancer activity Nucleic Acids Research. 17: 8185-8194. PMID 2478959 DOI: 10.1093/nar/17.20.8185  1
1989 Jones JM, Keller SA, Samuelson LC, Osborn L, Rosenberg MP, Meisler MH. A salivary amylase transgene is efficiently expressed in liver but not in parotid gland of transgenic mice. Nucleic Acids Research. 17: 6613-23. PMID 2476716 DOI: 10.1093/nar/17.16.6613  1
1989 Meisler MH, Howard G. Effects of insulin on gene transcription Annual Review of Physiology. 51: 701-714. PMID 2469384  1
1988 Samuelson LC, Keller PR, Darlington GJ, Meisler MH. Glucocorticoid and developmental regulation of amylase mRNAs in mouse liver cells Molecular and Cellular Biology. 8: 3857-3863. PMID 2464743  1
1988 Osborn L, Rosenberg MP, Keller SA, Ting CN, Meisler MH. Insulin response of a hybrid amylase/CAT gene in transgenic mice. The Journal of Biological Chemistry. 263: 16519-22. PMID 2460451  1
1988 Samuelson LC, Wiebauer K, Gumucio DL, Meisler MH. Expression of the human amylase genes: Recent origin of a salivary amylase promoter from an actin pseudogene Nucleic Acids Research. 16: 8261-8276. PMID 2458567 DOI: 10.1093/nar/16.17.8261  1
1988 Gumucio DL, Wiebauer K, Caldwell RM, Samuelson LC, Meisler MH. Concerted evolution of human amylase genes Molecular and Cellular Biology. 8: 1197-1205. PMID 2452973  1
1987 Meisler MH, Spence JE, Dixon JE, Caldwell RM, Minth CD, Beaudet AL. Exclusion of close linkage between the loci for cystic fibrosis and neuropeptide Y on human chromosome 7. Cytogenetics and Cell Genetics. 44: 175-6. PMID 3568765 DOI: 10.1159/000132367  1
1987 Stalvey JR, Meisler MH, Payne AH. Evidence that the same structural gene encodes testicular and adrenal 3 beta-hydroxysteroid dehydrogenase-isomerase. Biochemical Genetics. 25: 181-90. PMID 3472519 DOI: 10.1007/BF00498961  1
1987 Osborn L, Rosenberg MP, Keller SA, Meisler MH. Tissue-specific and insulin-dependent expression of a pancreatic amylase gene in transgenic mice. Molecular and Cellular Biology. 7: 326-34. PMID 2436036  1
1986 Takeuchi T, Gumucio DL, Yamada T, Meisler MH, Minth CD, Dixon JE, Eddy RE, Shows TB. Genes encoding pancreatic polypeptide and neuropeptide Y are on human chromosomes 17 and 7 Journal of Clinical Investigation. 77: 1038-1041. PMID 3753985  1
1986 Meisler MH, Antonucci TK, Treisman LO, Gumucio DL, Samuelson LC. Interstrain variation in amylase gene copy number and mRNA abundance in three mouse tissues Genetics. 113: 713-722. PMID 3488242  1
1986 Elliott RW, Samuelson LC, Lambert MS, Meisler MH. Assignment of pancreatic ribonuclease gene to mouse chromosome 14. Cytogenetics and Cell Genetics. 42: 110-2. PMID 3013507  1
1986 Darlington GJ, Tsai CC, Samuelson LC, Gumucio DL, Meisler MH. Simultaneous expression of salivary and pancreatic amylase genes in cultured mouse hepatoma cells Molecular and Cellular Biology. 6: 969-975. PMID 2431276  1
1985 Gumucio DL, Wiebauer K, Dranginis A, Samuelson LC, Treisman LO, Caldwell RM, Antonucci TK, Meisler MH. Evolution of the amylase multigene family. YBR/Ki mice express a pancreatic amylase gene which is silent in other strains Journal of Biological Chemistry. 260: 13483-13489. PMID 2414282  1
1985 Wiebauer K, Gumucio DL, Jones JM, Caldwell RM, Hartle HT, Meisler MH. A 78-kilobase region of mouse chromosome 3 contains salivary and pancreatic amylase genes and a pseudogene Proceedings of the National Academy of Sciences of the United States of America. 82: 5446-5449. PMID 2410924 DOI: 10.1073/pnas.82.16.5446  1
1984 Antonucci TK, von Deimling OH, Rosenblum BB, Skow LC, Meisler MH. Conserved linkage within a 4-cm region of mouse chromosome 9 and human chromosome 11 Genetics. 107: 463-475. PMID 6735174  1
1984 Meisler MH, Wanner L, Strahler J. Pigmentation and lysosomal phenotypes in mice doubly homozygous for both light-ear and pale-ear mutant alleles Journal of Heredity. 75: 103-106. PMID 6232310  1
1984 Dranginis A, Morley M, Nesbitt M, Rosenblum BB, Meisler MH. Independent regulation of nonallelic pancreatic amylase genes in diabetic mice Journal of Biological Chemistry. 259: 12216-12219. PMID 6207174  1
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