Ernest M. Wright, PhD DSc - Publications

Affiliations: 
Physiology UCLA School of Medicine, Los Angeles, CA, United States 

169 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Ghezzi C, Loo DDF, Wright EM. Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2. Diabetologia. PMID 30132032 DOI: 10.1007/s00125-018-4656-5  0.6
2017 Gorraitz E, Hirayama BA, Paz A, Wright EM, Loo DDF. Active site voltage clamp fluorometry of the sodium glucose cotransporter hSGLT1. Proceedings of the National Academy of Sciences of the United States of America. PMID 29087341 DOI: 10.1073/pnas.1713899114  0.6
2017 Wright EM, Ghezzi C, Loo DDF. Novel and Unexpected Functions of SGLTs. Physiology (Bethesda, Md.). 32: 435-443. PMID 29021363 DOI: 10.1152/physiol.00021.2017  0.6
2016 Zeuthen T, Gorraitz E, Her K, Wright EM, Loo DD. Structural and functional significance of water permeation through cotransporters. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791155 DOI: 10.1073/pnas.1613744113  0.32
2016 Adelman JL, Ghezzi C, Bisignano P, Loo DD, Choe S, Abramson J, Rosenberg JM, Wright EM, Grabe M. Stochastic steps in secondary active sugar transport. Proceedings of the National Academy of Sciences of the United States of America. PMID 27325773 DOI: 10.1073/pnas.1525378113  0.96
2016 Sala-Rabanal M, Hirayama BA, Ghezzi C, Liu J, Huang SC, Kepe V, Koepsell H, Yu A, Powell DR, Thorens B, Wright EM, Barrio JR. Revisiting the physiological roles of SGLTs and GLUTs using positron emission tomography in mice. (March 15, 2016). The Journal of Physiology. PMID 27018980 DOI: 10.1113/JP271904  0.96
2015 Scafoglio C, Hirayama BA, Kepe V, Liu J, Ghezzi C, Satyamurthy N, Moatamed NA, Huang J, Koepsell H, Barrio JR, Wright EM. Functional expression of sodium-glucose transporters in cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26170283 DOI: 10.1073/pnas.1511698112  0.96
2014 Ghezzi C, Hirayama BA, Gorraitz E, Loo DD, Liang Y, Wright EM. SGLT2 inhibitors act from the extracellular surface of the cell membrane. Physiological Reports. 2. PMID 24973332 DOI: 10.14814/phy2.12058  0.32
2014 Adelman JL, Sheng Y, Choe S, Abramson J, Wright EM, Rosenberg JM, Grabe M. Structural determinants of water permeation through the sodium-galactose transporter vSGLT. Biophysical Journal. 106: 1280-9. PMID 24655503 DOI: 10.1016/j.bpj.2014.01.006  0.96
2014 Ghezzi C, Gorraitz E, Hirayama BA, Loo DD, Grempler R, Mayoux E, Wright EM. Fingerprints of hSGLT5 sugar and cation selectivity. American Journal of Physiology. Cell Physiology. 306: C864-70. PMID 24573086 DOI: 10.1152/ajpcell.00027.2014  0.96
2014 Kazmier K, Sharma S, Islam SM, Roux B, Mchaourab HS, Wright EM. Conformational cycle and ion-coupling mechanism of the Na+/hydantoin transporter Mhp1 Proceedings of the National Academy of Sciences of the United States of America. 111: 14752-14757. DOI: 10.1073/pnas.1410431111/-/DCSupplemental  0.96
2013 Loo DD, Jiang X, Gorraitz E, Hirayama BA, Wright EM. Functional identification and characterization of sodium binding sites in Na symporters. Proceedings of the National Academy of Sciences of the United States of America. 110: E4557-66. PMID 24191006 DOI: 10.1073/pnas.1319218110  0.96
2013 Wright EM. Glucose transport families SLC5 and SLC50. Molecular Aspects of Medicine. 34: 183-96. PMID 23506865 DOI: 10.1016/j.mam.2012.11.002  0.96
2013 Yu AS, Hirayama BA, Timbol G, Liu J, Diez-Sampedro A, Kepe V, Satyamurthy N, Huang SC, Wright EM, Barrio JR. Regional distribution of SGLT activity in rat brain in vivo. American Journal of Physiology. Cell Physiology. 304: C240-7. PMID 23151803 DOI: 10.1152/ajpcell.00317.2012  0.96
2013 Hummel CS, Wright EM. Glucose Reabsorption in The Kidney Seldin and Geibisch's the Kidney. 2: 2393-2404. DOI: 10.1016/B978-0-12-381462-3.00070-7  0.96
2012 Jiang X, Loo DD, Hirayama BA, Wright EM. The importance of being aromatic: Ï€ interactions in sodium symporters. Biochemistry. 51: 9480-7. PMID 23116249 DOI: 10.1021/bi301329w  0.96
2012 Ghezzi C, Wright EM. Regulation of the human Na+-dependent glucose cotransporter hSGLT2. American Journal of Physiology. Cell Physiology. 303: C348-54. PMID 22673616 DOI: 10.1152/ajpcell.00115.2012  0.96
2012 Sala-Rabanal M, Hirayama BA, Loo DD, Chaptal V, Abramson J, Wright EM. Bridging the gap between structure and kinetics of human SGLT1. American Journal of Physiology. Cell Physiology. 302: C1293-305. PMID 22159082 DOI: 10.1152/ajpcell.00397.2011  0.96
2012 Hummel CS, Lu C, Liu J, Ghezzi C, Hirayama BA, Loo DD, Kepe V, Barrio JR, Wright EM. Structural selectivity of human SGLT inhibitors. American Journal of Physiology. Cell Physiology. 302: C373-82. PMID 21940664 DOI: 10.1152/ajpcell.00328.2011  0.96
2012 Wright EM, Sala-Rabanal M, Loo DDF, Hirayama BA. Sugar Absorption Physiology of the Gastrointestinal Tract. 2: 1583-1593. DOI: 10.1016/B978-0-12-382026-6.00058-0  0.96
2011 Wright EM, Loo DD, Hirayama BA. Biology of human sodium glucose transporters. Physiological Reviews. 91: 733-94. PMID 21527736 DOI: 10.1152/physrev.00055.2009  0.96
2011 Zampighi GA, Schietroma C, Zampighi LM, Woodruff M, Wright EM, Brecha NC. Conical tomography of a ribbon synapse: structural evidence for vesicle fusion. Plos One. 6: e16944. PMID 21390245 DOI: 10.1371/journal.pone.0016944  0.96
2011 Hummel CS, Lu C, Loo DD, Hirayama BA, Voss AA, Wright EM. Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2. American Journal of Physiology. Cell Physiology. 300: C14-21. PMID 20980548 DOI: 10.1152/ajpcell.00388.2010  0.96
2011 Hummel CS, Lu C, Loo DD, Hirayama BA, Voss AA, Wright EM. Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2 (American Journal of Physiology - Cell Physiology (2011) 300 (C14-C21) DOI: 10.1152/ajpcell.00388.2010) American Journal of Physiology - Cell Physiology. 300: C721. DOI: 10.1152/ajpcell.zh0-6564-corr.2011  0.96
2011 Wright EM, Hirayama B. SGLT1, sodium-glucose transporter Xpharm: the Comprehensive Pharmacology Reference. 1-6. DOI: 10.1016/B978-008055232-3.60489-1  0.96
2010 Watanabe A, Choe S, Chaptal V, Rosenberg JM, Wright EM, Grabe M, Abramson J. The mechanism of sodium and substrate release from the binding pocket of vSGLT. Nature. 468: 988-91. PMID 21131949 DOI: 10.1038/nature09580  0.96
2010 Choe S, Rosenberg JM, Abramson J, Wright EM, Grabe M. Water permeation through the sodium-dependent galactose cotransporter vSGLT. Biophysical Journal. 99: L56-8. PMID 20923633 DOI: 10.1016/j.bpj.2010.08.055  0.96
2010 Yu AS, Hirayama BA, Timbol G, Liu J, Basarah E, Kepe V, Satyamurthy N, Huang SC, Wright EM, Barrio JR. Functional expression of SGLTs in rat brain. American Journal of Physiology. Cell Physiology. 299: C1277-84. PMID 20826762 DOI: 10.1152/ajpcell.00296.2010  0.96
2009 Abramson J, Wright EM. Structure and function of Na(+)-symporters with inverted repeats. Current Opinion in Structural Biology. 19: 425-32. PMID 19631523 DOI: 10.1016/j.sbi.2009.06.002  0.96
2009 Bakris GL, Fonseca VA, Sharma K, Wright EM. Renal sodium-glucose transport: role in diabetes mellitus and potential clinical implications. Kidney International. 75: 1272-7. PMID 19357717 DOI: 10.1038/ki.2009.87  0.96
2009 Wright EM. Diseases of Renal Glucose Handling Genetic Diseases of the Kidney. 131-140. DOI: 10.1016/B978-0-12-449851-8.00007-3  0.96
2009 Martín MG, Wright EM. Disorders of Epithelial Transport in the Small Intestine Textbook of Gastroenterology, Fifth Edition. 1: 1259-1283. DOI: 10.1002/9781444303254.ch51  0.96
2008 Faham S, Watanabe A, Besserer GM, Cascio D, Specht A, Hirayama BA, Wright EM, Abramson J. The crystal structure of a sodium galactose transporter reveals mechanistic insights into Na+/sugar symport. Science (New York, N.Y.). 321: 810-4. PMID 18599740 DOI: 10.1126/science.1160406  0.96
2008 Loo DD, Hirayama BA, Sala-Rabanal M, Wright EM. How drugs interact with transporters: SGLT1 as a model. The Journal of Membrane Biology. 223: 87-106. PMID 18592293 DOI: 10.1007/s00232-008-9116-6  0.96
2008 Zampighi GA, Fain N, Zampighi LM, Cantele F, Lanzavecchia S, Wright EM. Conical electron tomography of a chemical synapse: polyhedral cages dock vesicles to the active zone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4151-60. PMID 18417694 DOI: 10.1523/JNEUROSCI.4639-07.2008  0.96
2008 Sala-Rabanal M, Loo DD, Hirayama BA, Wright EM. Molecular mechanism of dipeptide and drug transport by the human renal H+/oligopeptide cotransporter hPEPT2. American Journal of Physiology. Renal Physiology. 294: F1422-32. PMID 18367661 DOI: 10.1152/ajprenal.00030.2008  0.96
2007 Hirayama BA, Loo DD, Díez-Sampedro A, Leung DW, Meinild AK, Lai-Bing M, Turk E, Wright EM. Sodium-dependent reorganization of the sugar-binding site of SGLT1. Biochemistry. 46: 13391-406. PMID 17960916 DOI: 10.1021/bi701562k  0.96
2007 Wright EM, Hirayama BA, Loo DF. Active sugar transport in health and disease. Journal of Internal Medicine. 261: 32-43. PMID 17222166 DOI: 10.1111/j.1365-2796.2006.01746.x  0.96
2007 Voss AA, Díez-Sampedro A, Hirayama BA, Loo DD, Wright EM. Imino sugars are potent agonists of the human glucose sensor SGLT3. Molecular Pharmacology. 71: 628-34. PMID 17110502 DOI: 10.1124/mol.106.030288  0.96
2006 Loo DD, Hirayama BA, Karakossian MH, Meinild AK, Wright EM. Conformational dynamics of hSGLT1 during Na+/glucose cotransport. The Journal of General Physiology. 128: 701-20. PMID 17130520 DOI: 10.1085/jgp.200609643  0.96
2006 Zampighi GA, Zampighi LM, Fain N, Lanzavecchia S, Simon SA, Wright EM. Conical electron tomography of a chemical synapse: vesicles docked to the active zone are hemi-fused. Biophysical Journal. 91: 2910-8. PMID 16877508 DOI: 10.1529/biophysj.106.084814  0.96
2006 Sala-Rabanal M, Loo DD, Hirayama BA, Turk E, Wright EM. Molecular interactions between dipeptides, drugs and the human intestinal H+ -oligopeptide cotransporter hPEPT1. The Journal of Physiology. 574: 149-66. PMID 16627568 DOI: 10.1113/jphysiol.2006.107904  0.96
2006 Turk E, Gasymov OK, Lanza S, Horwitz J, Wright EM. A reinvestigation of the secondary structure of functionally active vSGLT, the vibrio sodium/galactose cotransporter. Biochemistry. 45: 1470-9. PMID 16445289 DOI: 10.1021/bi052160z  0.96
2005 Zampighi GA, Zampighi L, Fain N, Wright EM, Cantele F, Lanzavecchia S. Conical tomography II: A method for the study of cellular organelles in thin sections. Journal of Structural Biology. 151: 263-74. PMID 16084109 DOI: 10.1016/j.jsb.2005.05.008  0.96
2005 Eskandari S, Wright EM, Loo DD. Kinetics of the reverse mode of the Na+/glucose cotransporter. The Journal of Membrane Biology. 204: 23-32. PMID 16007500 DOI: 10.1007/s00232-005-0743-x  0.96
2005 Lanzavecchia S, Cantele F, Bellon PL, Zampighi L, Kreman M, Wright E, Zampighi GA. Conical tomography of freeze-fracture replicas: a method for the study of integral membrane proteins inserted in phospholipid bilayers. Journal of Structural Biology. 149: 87-98. PMID 15629660 DOI: 10.1016/j.jsb.2004.09.004  0.96
2005 Loo DD, Hirayama BA, Cha A, Bezanilla F, Wright EM. Perturbation analysis of the voltage-sensitive conformational changes of the Na+/glucose cotransporter. The Journal of General Physiology. 125: 13-36. PMID 15596535 DOI: 10.1085/jgp.200409150  0.96
2004 Wright EM, Loo DD, Hirayama BA, Turk E. Surprising versatility of Na+-glucose cotransporters: SLC5. Physiology (Bethesda, Md.). 19: 370-6. PMID 15546855 DOI: 10.1152/physiol.00026.2004  0.96
2004 Díez-Sampedro A, Loo DD, Wright EM, Zampighi GA, Hirayama BA. Coupled sodium/glucose cotransport by SGLT1 requires a negative charge at position 454. Biochemistry. 43: 13175-84. PMID 15476411 DOI: 10.1021/bi048652d  0.96
2004 Veenstra M, Lanza S, Hirayama BA, Turk E, Wright EM. Local conformational changes in the Vibrio Na+/galactose cotransporter. Biochemistry. 43: 3620-7. PMID 15035632 DOI: 10.1021/bi0357210  0.96
2004 Wright EM, Turk E. The sodium/glucose cotransport family SLC5. PflüGers Archiv : European Journal of Physiology. 447: 510-8. PMID 12748858 DOI: 10.1007/s00424-003-1063-6  0.96
2003 Wright EM, Martín MG, Turk E. Intestinal absorption in health and disease--sugars. Best Practice & Research. Clinical Gastroenterology. 17: 943-56. PMID 14642859 DOI: 10.1016/S1521-6918(03)00107-0  0.96
2003 Diez-Sampedro A, Hirayama BA, Osswald C, Gorboulev V, Baumgarten K, Volk C, Wright EM, Koepsell H. A glucose sensor hiding in a family of transporters. Proceedings of the National Academy of Sciences of the United States of America. 100: 11753-8. PMID 13130073 DOI: 10.1073/pnas.1733027100  0.96
2003 Sarkar HK, Wright EM, Boorer KJ, Loo DD. Electrophysiological properties of the mouse Na+/Cl(-)-dependent taurine transporter (mTauT-1): steady-state kinetics: stoichiometry of taurine transport. Advances in Experimental Medicine and Biology. 526: 197-204. PMID 12908601  0.96
2003 Quick M, Tomasevic J, Wright EM. Functional asymmetry of the human Na+/glucose transporter (hSGLT1) in bacterial membrane vesicles. Biochemistry. 42: 9147-52. PMID 12885248 DOI: 10.1021/bi034842x  0.96
2003 Shu Y, Leabman MK, Feng B, Mangravite LM, Huang CC, Stryke D, Kawamoto M, Johns SJ, DeYoung J, Carlson E, Ferrin TE, Herskowitz I, Giacomini KM. Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1. Proceedings of the National Academy of Sciences of the United States of America. 100: 5902-7. PMID 12719534 DOI: 10.1073/pnas.0730858100  0.96
2003 Leabman MK, Huang CC, DeYoung J, Carlson EJ, Taylor TR, de la Cruz M, Johns SJ, Stryke D, Kawamoto M, Urban TJ, Kroetz DL, Ferrin TE, Clark AG, Risch N, Herskowitz I, et al. Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proceedings of the National Academy of Sciences of the United States of America. 100: 5896-901. PMID 12719533 DOI: 10.1073/pnas.0730857100  0.96
2003 Zampighi GA, Kreman M, Lanzavecchia S, Turk E, Eskandari S, Zampighi L, Wright EM. Structure of functional single AQP0 channels in phospholipid membranes. Journal of Molecular Biology. 325: 201-10. PMID 12473462 DOI: 10.1016/S0022-2836(02)01200-7  0.96
2002 Sacher A, Nelson N, Ogi JT, Wright EM, Loo DD, Eskandari S. Presteady-state and steady-state kinetics and turnover rate of the mouse gamma-aminobutyric acid transporter (mGAT3). The Journal of Membrane Biology. 190: 57-73. PMID 12422272 DOI: 10.1007/s00232-002-1024-6  0.96
2002 Fischer WN, Loo DD, Koch W, Ludewig U, Boorer KJ, Tegeder M, Rentsch D, Wright EM, Frommer WB. Low and high affinity amino acid H+-cotransporters for cellular import of neutral and charged amino acids. The Plant Journal : For Cell and Molecular Biology. 29: 717-31. PMID 12148530 DOI: 10.1046/j.1365-313X.2002.01248.x  0.96
2002 Wright EM, Turk E, Martin MG. Molecular basis for glucose-galactose malabsorption. Cell Biochemistry and Biophysics. 36: 115-21. PMID 12139397 DOI: 10.1385/CBB:36:2-3:115  0.96
2002 Loo DD, Wright EM, Zeuthen T. Water pumps. The Journal of Physiology. 542: 53-60. PMID 12096049 DOI: 10.1113/jphysiol.2002.018713  0.96
2002 Quick M, Wright EM. Employing Escherichia coli to functionally express, purify, and characterize a human transporter. Proceedings of the National Academy of Sciences of the United States of America. 99: 8597-601. PMID 12077304 DOI: 10.1073/pnas.132266599  0.96
2002 le Coutre J, Turk E, Kaback HR, Wright EM. Ligand-induced differences in secondary structure of the Vibrio parahaemolyticus Na+/galactose cotransporter. Biochemistry. 41: 8082-6. PMID 12069600 DOI: 10.1021/bi025692d  0.96
2002 Leung DW, Turk E, Kim O, Wright EM. Functional expression of the Vibrio parahaemolyticus Na+/galactose (vSGLT) cotransporter in Xenopus laevis oocytes. The Journal of Membrane Biology. 187: 65-70. PMID 12029378 DOI: 10.1007/s00232-001-0152-8  0.96
2002 Veenstra M, Turk E, Wright EM. A ligand-dependent conformational change of the Na+/galactose cotransporter of Vibrio parahaemolyticus, monitored by tryptophan fluorescence. The Journal of Membrane Biology. 185: 249-55. PMID 11891582 DOI: 10.1007/s00232-001-0127-9  0.96
2002 Eskandari S, Zampighi GA, Leung DW, Wright EM, Loo DD. Inhibition of gap junction hemichannels by chloride channel blockers. The Journal of Membrane Biology. 185: 93-102. PMID 11891568 DOI: 10.1007/s00232-001-0115-0  0.96
2002 Meinild AK, Hirayama BA, Wright EM, Loo DD. Fluorescence studies of ligand-induced conformational changes of the Na(+)/glucose cotransporter. Biochemistry. 41: 1250-8. PMID 11802724 DOI: 10.1021/bi011661r  0.96
2001 Díez-Sampedro A, Wright EM, Hirayama BA. Residue 457 controls sugar binding and transport in the Na(+)/glucose cotransporter. The Journal of Biological Chemistry. 276: 49188-94. PMID 11602601 DOI: 10.1074/jbc.M108286200  0.96
2001 Hirayama BA, Díez-Sampedro A, Wright EM. Common mechanisms of inhibition for the Na+/glucose (hSGLT1) and Na+/Cl-/GABA (hGAT1) cotransporters. British Journal of Pharmacology. 134: 484-95. PMID 11588102 DOI: 10.1038/sj.bjp.0704274  0.96
2001 Meinild AK, Loo DD, Hirayama BA, Gallardo E, Wright EM. Evidence for the involvement of Ala 166 in coupling Na(+) to sugar transport through the human Na(+)/glucose cotransporter. Biochemistry. 40: 11897-904. PMID 11570890 DOI: 10.1021/bi011026l  0.96
2001 Panayotova-Heiermann M, Wright EM. Mapping the urea channel through the rabbit Na(+)-glucose cotransporter SGLT1. The Journal of Physiology. 535: 419-25. PMID 11533134 DOI: 10.1111/j.1469-7793.2001.00419.x  0.96
2001 Cornford EM, Cornford ME, Wright EM, Bruckner DA, Sampogna S, Hirayama BA. Human cerebral cysticercosis: immunolocalization of a sodium-dependent glucose cotransporter (SGLT) in larval and adult tapeworms. The Journal of Parasitology. 87: 510-21. PMID 11426712 DOI: 10.1645/0022-3395(2001)087[0510:HCCIOA]2.0.CO;2  0.96
2001 Zeuthen T, Meinild AK, Loo DD, Wright EM, Klaerke DA. Isotonic transport by the Na+-glucose cotransporter SGLT1 from humans and rabbit. The Journal of Physiology. 531: 631-44. PMID 11251046 DOI: 10.1111/j.1469-7793.2001.0631h.x  0.96
2001 Díez-Sampedro A, Eskandari S, Wright EM, Hirayama BA. Na+-to-sugar stoichiometry of SGLT3. American Journal of Physiology. Renal Physiology. 280: F278-82. PMID 11208603  0.96
2001 Wright EM. Renal Na(+)-glucose cotransporters. American Journal of Physiology. Renal Physiology. 280: F10-8. PMID 11133510  0.96
2001 Quick M, Loo DD, Wright EM. Neutralization of a conserved amino acid residue in the human Na+/glucose transporter (hSGLT1) generates a glucose-gated H+ channel. The Journal of Biological Chemistry. 276: 1728-34. PMID 11024018 DOI: 10.1074/jbc.M005521200  0.96
2000 Wright EM, Loo DD. Coupling between Na+, sugar, and water transport across the intestine. Annals of the New York Academy of Sciences. 915: 54-66. PMID 11193601  0.96
2000 Leung DW, Loo DD, Hirayama BA, Zeuthen T, Wright EM. Urea transport by cotransporters. The Journal of Physiology. 528: 251-7. PMID 11034615  0.96
2000 Loo DD, Eskandari S, Boorer KJ, Sarkar HK, Wright EM. Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1. The Journal of Biological Chemistry. 275: 37414-22. PMID 10973981 DOI: 10.1074/jbc.M007241200  0.96
2000 Díez-Sampedro A, Lostao MP, Wright EM, Hirayama BA. Glycoside binding and translocation in Na(+)-dependent glucose cotransporters: comparison of SGLT1 and SGLT3. The Journal of Membrane Biology. 176: 111-7. PMID 10926676 DOI: 10.1007/s00232001081  0.96
2000 Eskandari S, Kreman M, Kavanaugh MP, Wright EM, Zampighi GA. Pentameric assembly of a neuronal glutamate transporter. Proceedings of the National Academy of Sciences of the United States of America. 97: 8641-6. PMID 10900021 DOI: 10.1073/pnas.97.15.8641  0.96
2000 Xie Z, Turk E, Wright EM. Characterization of the Vibrio parahaemolyticus Na+/Glucose cotransporter. A bacterial member of the sodium/glucose transporter (SGLT) family. The Journal of Biological Chemistry. 275: 25959-64. PMID 10852908 DOI: 10.1074/jbc.M002687200  0.96
2000 Turk E, Kim O, le Coutre J, Whitelegge JP, Eskandari S, Lam JT, Kreman M, Zampighi G, Faull KF, Wright EM. Molecular characterization of Vibrio parahaemolyticus vSGLT: a model for sodium-coupled sugar cotransporters. The Journal of Biological Chemistry. 275: 25711-6. PMID 10835424 DOI: 10.1074/jbc.M003127200  0.96
2000 Meinild AK, Loo DD, Pajor AM, Zeuthen T, Wright EM. Water transport by the renal Na(+)-dicarboxylate cotransporter. American Journal of Physiology. Renal Physiology. 278: F777-83. PMID 10807589  0.96
2000 Martín MG, Wang J, Solorzano-Vargas RS, Lam JT, Turk E, Wright EM. Regulation of the human Na(+)-glucose cotransporter gene, SGLT1, by HNF-1 and Sp1. American Journal of Physiology. Gastrointestinal and Liver Physiology. 278: G591-603. PMID 10762614  0.96
2000 le Coutre J, Whitelegge JP, Gross A, Turk E, Wright EM, Kaback HR, Faull KF. Proteomics on full-length membrane proteins using mass spectrometry. Biochemistry. 39: 4237-42. PMID 10757971 DOI: 10.1021/bi000150m  0.96
2000 Wright EM. Chapter 13 Molecular aspects of intestinal brush-border Na+/glucose transport Current Topics in Membranes. 50: 499-516.  0.96
1999 Loo DD, Wright EM, Meinild AK, Klaerke DA, Zeuthen T. Commentary on "Epithelial Fluid Transport--A Century of Investigation" News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 14: 98-100. PMID 11390830  0.32
1999 Panayotova-Heiermann M, Leung DW, Hirayama BA, Wright EM. Purification and functional reconstitution of a truncated human Na(+)/glucose cotransporter (SGLT1) expressed in E. coli. Febs Letters. 459: 386-90. PMID 10526170 DOI: 10.1016/S0014-5793(99)01292-2  0.96
1999 Eskandari S, Snyder PM, Kreman M, Zampighi GA, Welsh MJ, Wright EM. Number of subunits comprising the epithelial sodium channel. The Journal of Biological Chemistry. 274: 27281-6. PMID 10480948 DOI: 10.1074/jbc.274.38.27281  0.96
1999 Loo DD, Hirayama BA, Meinild AK, Chandy G, Zeuthen T, Wright EM. Passive water and ion transport by cotransporters. The Journal of Physiology. 518: 195-202. PMID 10373701 DOI: 10.1111/j.1469-7793.1999.0195r.x  0.96
1999 Zampighi GA, Loo DD, Kreman M, Eskandari S, Wright EM. Functional and morphological correlates of connexin50 expressed in Xenopus laevis oocytes. The Journal of General Physiology. 113: 507-24. PMID 10102933 DOI: 10.1085/jgp.113.4.507  0.96
1999 Lam JT, Martín MG, Turk E, Hirayama BA, Bosshard NU, Steinmann B, Wright EM. Missense mutations in SGLT1 cause glucose-galactose malabsorption by trafficking defects. Biochimica Et Biophysica Acta. 1453: 297-303. PMID 10036327 DOI: 10.1016/S0925-4439(98)00109-4  0.96
1999 Loo DDF, Wright EM, Meinild AK, Klaerke DA, Zeuthen T. Commentary on "epithelial fluid transport - A century of investigation" News in Physiological Sciences. 14: 98-100.  0.96
1998 Urdaneta E, Barber A, Wright EM, Lostao MP. Functional expression of the rabbit intestinal Na+/L-proline cotransporter (IMINO system) in Xenopus laevis oocytes. Journal of Physiology and Biochemistry. 54: 155-60. PMID 10217212  0.96
1998 Wright EM. I. Glucose galactose malabsorption. The American Journal of Physiology. 275: G879-82. PMID 9815014  0.96
1998 Wright EM, Loo DD, Panayotova-Heiermann M, Hirayama BA, Turk E, Eskandari S, Lam JT. Structure and function of the Na+/glucose cotransporter. Acta Physiologica Scandinavica. Supplementum. 643: 257-64. PMID 9789568  0.96
1998 Eskandari S, Wright EM, Kreman M, Starace DM, Zampighi GA. Structural analysis of cloned plasma membrane proteins by freeze-fracture electron microscopy. Proceedings of the National Academy of Sciences of the United States of America. 95: 11235-40. PMID 9736719  0.96
1998 Panayotova-Heiermann M, Loo DD, Lam JT, Wright EM. Neutralization of conservative charged transmembrane residues in the Na+/glucose cotransporter SGLT1. Biochemistry. 37: 10522-8. PMID 9671524 DOI: 10.1021/bi9800395  0.96
1998 Loo DD, Hirayama BA, Gallardo EM, Lam JT, Turk E, Wright EM. Conformational changes couple Na+ and glucose transport. Proceedings of the National Academy of Sciences of the United States of America. 95: 7789-94. PMID 9636229 DOI: 10.1073/pnas.95.13.7789  0.96
1998 Mackenzie B, Loo DD, Wright EM. Relationships between Na+/glucose cotransporter (SGLT1) currents and fluxes. The Journal of Membrane Biology. 162: 101-6. PMID 9538503 DOI: 10.1007/s002329900347  0.96
1998 Meinild A, Klaerke DA, Loo DD, Wright EM, Zeuthen T. The human Na+-glucose cotransporter is a molecular water pump. The Journal of Physiology. 508: 15-21. PMID 9490810  0.96
1998 Wright EM. Genetic disorders of membrane transport I. Glucose galactose malabsorption American Journal of Physiology. 275: G879-G882.  0.96
1998 Loo DDF, Hirayama BA, Zeuthen T, Meinild AK, Wright EM. Separate pathways for passive H2O and Na+ transport through cotransport proteins Faseb Journal. 12: A1017.  0.96
1997 Zeuthen T, Meinild AK, Klaerke DA, Loo DD, Wright EM, Belhage B, Litman T. Water transport by the Na+/glucose cotransporter under isotonic conditions. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 89: 307-12. PMID 9468601  0.32
1997 Eskandari S, Loo DD, Dai G, Levy O, Wright EM, Carrasco N. Thyroid Na+/I- symporter. Mechanism, stoichiometry, and specificity. The Journal of Biological Chemistry. 272: 27230-8. PMID 9341168 DOI: 10.1074/jbc.272.43.27230  0.96
1997 Turk E, Wright EM. Membrane topology motifs in the SGLT cotransporter family. The Journal of Membrane Biology. 159: 1-20. PMID 9309206  0.32
1997 Panayotova-Heiermann M, Eskandari S, Turk E, Zampighi GA, Wright EM. Five transmembrane helices form the sugar pathway through the Na+/glucose cotransporter. The Journal of Biological Chemistry. 272: 20324-7. PMID 9252334 DOI: 10.1074/jbc.272.33.20324  0.96
1997 Martín MG, Lostao MP, Turk E, Lam J, Kreman M, Wright EM. Compound missense mutations in the sodium/D-glucose cotransporter result in trafficking defects. Gastroenterology. 112: 1206-12. PMID 9098004  0.56
1997 Wright EM, Hirsch JR, Loo DD, Zampighi GA. Regulation of Na+/glucose cotransporters. The Journal of Experimental Biology. 200: 287-93. PMID 9050236  0.32
1997 Hazama A, Loo DD, Wright EM. Presteady-state currents of the rabbit Na+/glucose cotransporter (SGLT1). The Journal of Membrane Biology. 155: 175-86. PMID 9049111  0.32
1997 Hirayama BA, Loo DD, Wright EM. Cation effects on protein conformation and transport in the Na+/glucose cotransporter. The Journal of Biological Chemistry. 272: 2110-5. PMID 8999910  0.32
1996 Mackenzie B, Loo DD, Panayotova-Heiermann M, Wright EM. Biophysical characteristics of the pig kidney Na+/glucose cotransporter SGLT2 reveal a common mechanism for SGLT1 and SGLT2. The Journal of Biological Chemistry. 271: 32678-83. PMID 8955098 DOI: 10.1074/jbc.271.51.32678  0.96
1996 Loo DD, Zeuthen T, Chandy G, Wright EM. Cotransport of water by the Na+/glucose cotransporter. Proceedings of the National Academy of Sciences of the United States of America. 93: 13367-70. PMID 8917597 DOI: 10.1073/pnas.93.23.13367  0.96
1996 Martín MG, Turk E, Kerner C, Zabel B, Wirth S, Wright EM. Prenatal identification of a heterozygous status in two fetuses at risk for glucose-galactose malabsorption. Prenatal Diagnosis. 16: 458-62. PMID 8844006 DOI: 10.1002/(SICI)1097-0223(199605)16:5<458::AID-PD873>3.0.CO;2-U  0.32
1996 Boorer KJ, Loo DD, Frommer WB, Wright EM. Transport mechanism of the cloned potato H+/sucrose cotransporter StSUT1. The Journal of Biological Chemistry. 271: 25139-44. PMID 8810269  0.32
1996 Wright EM, Loo DD, Turk E, Hirayama BA. Sodium cotransporters. Current Opinion in Cell Biology. 8: 468-73. PMID 8791459  0.32
1996 Loo DD, Hirsch JR, Sarkar HK, Wright EM. Regulation of the mouse retinal taurine transporter (TAUT) by protein kinases in Xenopus oocytes. Febs Letters. 392: 250-4. PMID 8774855  0.32
1996 Hirayama BA, Lostao MP, Panayotova-Heiermann M, Loo DD, Turk E, Wright EM. Kinetic and specificity differences between rat, human, and rabbit Na+-glucose cotransporters (SGLT-1). The American Journal of Physiology. 270: G919-26. PMID 8764197  0.56
1996 Hirsch JR, Loo DD, Wright EM. Regulation of Na+/glucose cotransporter expression by protein kinases in Xenopus laevis oocytes. The Journal of Biological Chemistry. 271: 14740-6. PMID 8663046  0.32
1996 Panayotova-Heiermann M, Loo DD, Kong CT, Lever JE, Wright EM. Sugar binding to Na+/glucose cotransporters is determined by the carboxyl-terminal half of the protein. The Journal of Biological Chemistry. 271: 10029-34. PMID 8626557 DOI: 10.1074/jbc.271.17.10029  0.96
1996 Mackenzie B, Loo DD, Fei Y, Liu WJ, Ganapathy V, Leibach FH, Wright EM. Mechanisms of the human intestinal H+-coupled oligopeptide transporter hPEPT1. The Journal of Biological Chemistry. 271: 5430-7. PMID 8621398 DOI: 10.1074/jbc.271.10.5430  0.96
1996 Boorer KJ, Frommer WB, Bush DR, Kreman M, Loo DD, Wright EM. Kinetics and specificity of a H+/amino acid transporter from Arabidopsis thaliana. The Journal of Biological Chemistry. 271: 2213-20. PMID 8567681  0.32
1996 Turk E, Kerner CJ, Lostao MP, Wright EM. Membrane topology of the human Na+/glucose cotransporter SGLT1. The Journal of Biological Chemistry. 271: 1925-34. PMID 8567640  0.56
1996 Martín MG, Turk E, Lostao MP, Kerner C, Wright EM. Defects in Na+/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption. Nature Genetics. 12: 216-20. PMID 8563765 DOI: 10.1038/ng0296-216  0.56
1995 Zampighi GA, Kreman M, Boorer KJ, Loo DD, Bezanilla F, Chandy G, Hall JE, Wright EM. A method for determining the unitary functional capacity of cloned channels and transporters expressed in Xenopus laevis oocytes. The Journal of Membrane Biology. 148: 65-78. PMID 8558603 DOI: 10.1007/BF00234157  0.96
1995 Lostao MP, Hirayama BA, Panayotova-Heiermann M, Sampogna SL, Bok D, Wright EM. Arginine-427 in the Na+/glucose cotransporter (SGLT1) is involved in trafficking to the plasma membrane. Febs Letters. 377: 181-4. PMID 8543046  0.56
1995 Panayotova-Heiermann M, Loo DD, Wright EM. Kinetics of steady-state currents and charge movements associated with the rat Na+/glucose cotransporter. The Journal of Biological Chemistry. 270: 27099-105. PMID 7592962  0.56
1995 Hager K, Hazama A, Kwon HM, Loo DD, Handler JS, Wright EM. Kinetics and specificity of the renal Na+/myo-inositol cotransporter expressed in Xenopus oocytes. The Journal of Membrane Biology. 143: 103-13. PMID 7537337  0.32
1994 Turk E, Martín MG, Wright EM. Structure of the human Na+/glucose cotransporter gene SGLT1. The Journal of Biological Chemistry. 269: 15204-9. PMID 8195156  0.32
1994 Mackenzie B, Panayotova-Heiermann M, Loo DD, Lever JE, Wright EM. SAAT1 is a low affinity Na+/glucose cotransporter and not an amino acid transporter. A reinterpretation. The Journal of Biological Chemistry. 269: 22488-91. PMID 8077195  0.96
1994 Hirayama BA, Loo DD, Wright EM. Protons drive sugar transport through the Na+/glucose cotransporter (SGLT1). The Journal of Biological Chemistry. 269: 21407-10. PMID 8063771  0.32
1994 Panayotova-Heiermann M, Loo DD, Lostao MP, Wright EM. Sodium/D-glucose cotransporter charge movements involve polar residues. The Journal of Biological Chemistry. 269: 21016-20. PMID 8063719  0.56
1994 Boorer KJ, Loo DD, Wright EM. Steady-state and presteady-state kinetics of the H+/hexose cotransporter (STP1) from Arabidopsis thaliana expressed in Xenopus oocytes. The Journal of Biological Chemistry. 269: 20417-24. PMID 8051137  0.32
1994 Hirayama B, Hazama A, Loo DF, Wright EM, Kisby GE. Transport of cycasin by the intestinal Na+/glucose cotransporter. Biochimica Et Biophysica Acta. 1193: 151-4. PMID 8038185  0.32
1994 Lostao MP, Hirayama BA, Loo DD, Wright EM. Phenylglucosides and the Na+/glucose cotransporter (SGLT1): analysis of interactions. The Journal of Membrane Biology. 142: 161-70. PMID 7884808  0.56
1994 Wright EM, Loo DD, Panayotova-Heiermann M, Lostao MP, Hirayama BH, Mackenzie B, Boorer K, Zampighi G. 'Active' sugar transport in eukaryotes. The Journal of Experimental Biology. 196: 197-212. PMID 7823022  0.96
1994 Wright EM, Loo DD, Panayotova-Heiermann M, Boorer KJ. Mechanisms of Na(+)-glucose cotransport. Biochemical Society Transactions. 22: 646-50. PMID 7821655  0.56
1993 Loo DD, Hazama A, Supplisson S, Turk E, Wright EM. Relaxation kinetics of the Na+/glucose cotransporter. Proceedings of the National Academy of Sciences of the United States of America. 90: 5767-71. PMID 8516326  0.96
1993 Parent L, Wright EM. Electrophysiology of the Na+/glucose cotransporter. Society of General Physiologists Series. 48: 263-81. PMID 8503050  0.96
1993 Wright EM, Hirayama B, Hazama A, Loo DD, Supplisson S, Turk E, Hager KM. The sodium/glucose cotransporter (SGLT1). Society of General Physiologists Series. 48: 229-41. PMID 8503046  0.96
1993 Lescale-Matys L, Dyer J, Scott D, Freeman TC, Wright EM, Shirazi-Beechey SP. Regulation of the ovine intestinal Na+/glucose co-transporter (SGLT1) is dissociated from mRNA abundance. The Biochemical Journal. 291: 435-40. PMID 8484724  0.96
1993 Hung BC, Loo DD, Wright EM. Regulation of mouse choroid plexus apical Cl- and K+ channels by serotonin. Brain Research. 617: 285-95. PMID 8402156  0.32
1993 Turk E, Klisak I, Bacallao R, Sparkes RS, Wright EM. Assignment of the human Na+/glucose cotransporter gene SGLT1 to chromosome 22q13.1. Genomics. 17: 752-4. PMID 8244393 DOI: 10.1006/geno.1993.1399  0.32
1992 Parent L, Supplisson S, Loo DD, Wright EM. Electrogenic properties of the cloned Na+/glucose cotransporter: I. Voltage-clamp studies. The Journal of Membrane Biology. 125: 49-62. PMID 1542106 DOI: 10.1007/BF00235797  0.96
1992 Wright EM, Turk E, Hager K, Lescale-Matys L, Hirayama B, Supplisson S, Loo DD. The Na+/glucose cotransporter (SGLT1). Acta Physiologica Scandinavica. Supplementum. 607: 201-7. PMID 1449065  0.96
1992 Wright EM, Hager KM, Turk E. Sodium cotransport proteins. Current Opinion in Cell Biology. 4: 696-702. PMID 1419051  0.32
1992 Wells RG, Pajor AM, Kanai Y, Turk E, Wright EM, Hediger MA. Cloning of a human kidney cDNA with similarity to the sodium-glucose cotransporter. The American Journal of Physiology. 263: F459-65. PMID 1415574  0.32
1992 Parent L, Supplisson S, Loo DD, Wright EM. Electrogenic properties of the cloned Na+/glucose cotransporter: II. A transport model under nonrapid equilibrium conditions. The Journal of Membrane Biology. 125: 63-79. PMID 1294062 DOI: 10.1007/BF00235798  0.96
1991 Birnir B, Loo DD, Wright EM. Voltage-clamp studies of the Na+/glucose cotransporter cloned from rabbit small intestine. PflüGers Archiv : European Journal of Physiology. 418: 79-85. PMID 2041729 DOI: 10.1007/BF00370455  0.96
1991 Turk E, Zabel B, Mundlos S, Dyer J, Wright EM. Glucose/galactose malabsorption caused by a defect in the Na+/glucose cotransporter. Nature. 350: 354-6. PMID 2008213 DOI: 10.1038/350354a0  0.32
1991 Wright EM, Turk E, Zabel B, Mundlos S, Dyer J. Molecular genetics of intestinal glucose transport. The Journal of Clinical Investigation. 88: 1435-40. PMID 1939637 DOI: 10.1172/JCI115451  0.32
1990 Stevens BR, Fernandez A, Hirayama B, Wright EM, Kempner ES. Intestinal brush border membrane Na+/glucose cotransporter functions in situ as a homotetramer. Proceedings of the National Academy of Sciences of the United States of America. 87: 1456-60. PMID 2304910  0.32
1990 Coady MJ, Pajor AM, Toloza EM, Wright EM. Expression of mammalian renal transporters in Xenopus laevis oocytes. Archives of Biochemistry and Biophysics. 283: 130-4. PMID 2241165 DOI: 10.1016/0003-9861(90)90622-6  0.96
1990 Coady MJ, Pajor AM, Wright EM. Sequence homologies among intestinal and renal Na+/glucose cotransporters. The American Journal of Physiology. 259: C605-10. PMID 2221040  0.96
1990 Birnir B, Lee HS, Hediger MA, Wright EM. Expression and characterization of the intestinal Na+/glucose cotransporter in COS-7 cells. Biochimica Et Biophysica Acta. 1048: 100-4. PMID 2105101 DOI: 10.1016/0167-4781(90)90028-Z  0.96
1990 Umbach JA, Coady MJ, Wright EM. Intestinal Na+/glucose cotransporter expressed in Xenopus oocytes is electrogenic. Biophysical Journal. 57: 1217-24. PMID 1697483 DOI: 10.1016/S0006-3495(90)82640-0  0.96
1989 Ikeda TS, Hwang ES, Coady MJ, Hirayama BA, Hediger MA, Wright EM. Characterization of a Na+/glucose cotransporter cloned from rabbit small intestine. The Journal of Membrane Biology. 110: 87-95. PMID 2795642 DOI: 10.1007/BF01870995  0.96
1989 Wright EM, Hediger MA, Coady MJ, Hirayama B, Turk E. Molecular biology of Na+/glucose cotransport. Biochemical Society Transactions. 17: 810-1. PMID 2695358  0.96
1989 Hediger MA, Turk E, Pajor AM, Wright EM. Molecular genetics of the human Na+/glucose cotransporter. Klinische Wochenschrift. 67: 843-6. PMID 2681963  0.32
1977 Wright EM, Diamond JM. Anion selectivity in biological systems. Physiological Reviews. 57: 109-56. PMID 834775  0.96
1971 Barry PH, Diamond JM, Wright EM. The mechanism of cation permeation in rabbit gallbladder : Dilution potentials and biionic potentials. The Journal of Membrane Biology. 4: 358-94. PMID 24174247 DOI: 10.1007/BF02431979  0.96
1971 Wright EM, Barry PH, Diamond JM. The mechanism of cation permeation in rabbit gallbladder : Conductances, the current-voltage relation, the concentration dependence of anion-cation discrimination, and the calcium competition effect. The Journal of Membrane Biology. 4: 331-57. PMID 24174246 DOI: 10.1007/BF02431978  0.96
1969 Diamond JM, Wright EM. Biological membranes: the physical basis of ion and nonelectrolyte selectivity. Annual Review of Physiology. 31: 581-646. PMID 4885777 DOI: 10.1146/annurev.ph.31.030169.003053  0.96
1969 Diamond JM, Wright EM. Molecular forces governing non-electrolyte permeation through cell membranes. Proceedings of the Royal Society of London. Series B, Biological Sciences. 171: 273-316. PMID 4388931  0.96
1969 Wright EM, Diamond JM. Patterns of non-electrolyte permeability. Proceedings of the Royal Society of London. Series B, Biological Sciences. 171: 227-71. PMID 4388930  0.96
1969 Wright EM, Diamond JM. An electrical method of measuring non-electrolyte permeability. Proceedings of the Royal Society of London. Series B, Biological Sciences. 171: 203-25. PMID 4388929  0.96
1968 Wright EM, Diamond JM. Effects of pH and polyvalent cations on the selective permeability of gall-bladder epithelium to monovalent ions. Biochimica Et Biophysica Acta. 163: 57-74. PMID 5666778  0.96
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