Elizabeta Nemeth, PhD - Publications

Affiliations: 
UCLA School of Medicine, Los Angeles, CA, United States 

149 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Goncalves Monteiro D, van Dijk JWA, Aliyanto R, Fung E, Nemeth E, Ganz T, Rosengren J, Clark RJ. Pursuing Orally Bioavailable Hepcidin Analogues via Cyclic -Methylated Mini-Hepcidins. Biomedicines. 9. PMID 33567510 DOI: 10.3390/biomedicines9020164  0.52
2020 Deshpande CN, Azucenas CR, Qiao B, Nomura N, Xin V, Font J, Iwata S, Ganz T, Nemeth E, Mackenzie B, Jormakka M. Isolation and thermal stabilization of mouse ferroportin. Febs Open Bio. PMID 33190422 DOI: 10.1002/2211-5463.13039  0.52
2020 Jerzak KJ, Lohmann AE, Ennis M, Nemeth E, Ganz T, Goodwin PJ. Prognostic associations of plasma hepcidin in women with early breast cancer. Breast Cancer Research and Treatment. PMID 32960376 DOI: 10.1007/s10549-020-05903-z  0.52
2020 Gutschow P, Han H, Olbina G, Westerman K, Nemeth E, Ganz T, Copeland K, Westerman M, Ostland V. Clinical Immunoassay for Human Hepcidin Predicts Iron Deficiency in First-Time Blood Donors. The Journal of Applied Laboratory Medicine. PMID 32674118 DOI: 10.1093/jalm/jfaa038  0.52
2020 Zhang V, Ganz T, Nemeth E, Kim A. Iron overload causes a mild and transient increase in acute lung injury. Physiological Reports. 8: e14470. PMID 32596989 DOI: 10.14814/phy2.14470  0.52
2020 Sangkhae V, Fisher AL, Chua KJ, Ruchala P, Ganz T, Nemeth E. Maternal Hepcidin Determines Embryo Iron Homeostasis. Blood. PMID 32584957 DOI: 10.1182/blood.2020005745  0.52
2020 Kautz L, Jung G, Valore EV, Rivella S, Nemeth E, Ganz T. Author Correction: Identification of erythroferrone as an erythroid regulator of iron metabolism. Nature Genetics. PMID 32107478 DOI: 10.1038/s41588-019-0548-y  0.52
2020 Fisher AL, Sangkhae V, Presicce P, Chougnet CA, Jobe AH, Kallapur SG, Tabbah SM, Buhimschi CS, Buhimschi IA, Ganz T, Nemeth E. Fetal and amniotic fluid iron homeostasis in healthy and complicated murine, macaque, and human pregnancy. Jci Insight. PMID 31990688 DOI: 10.1172/jci.insight.135321  0.52
2019 Sangkhae V, Fisher AL, Wong S, Koenig MD, Tussing-Humphreys L, Chu A, Lelić M, Ganz T, Nemeth E. Effects of maternal iron status on placental and fetal iron homeostasis. The Journal of Clinical Investigation. PMID 31661462 DOI: 10.1172/JCI127341  0.52
2019 Bondu S, Alary AS, Lefèvre C, Houy A, Jung G, Lefebvre T, Rombaut D, Boussaid I, Bousta A, Guillonneau F, Perrier P, Alsafadi S, Wassef M, Margueron R, Rousseau A, ... ... Nemeth E, et al. A variant erythroferrone disrupts iron homeostasis in -mutated myelodysplastic syndrome. Science Translational Medicine. 11. PMID 31292266 DOI: 10.1126/scitranslmed.aav5467  0.52
2019 Micewicz ED, Iwamoto KS, Ratikan JA, Nguyen C, Xie MW, Cheng G, Boxx GM, Deriu E, Damoiseaux RD, Whitelegge JP, Ruchala PP, Avetisyan R, Jung ME, Lawson G, Nemeth E, et al. The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation. Radiation Research. PMID 30730284 DOI: 10.1667/RR15231.1  0.52
2019 Chen Q, Yang Y, Hou J, Shu Q, Yin Y, Fu W, Han F, Hou T, Zeng C, Nemeth E, Linzmeier R, Ganz T, Fang X. Increased gene copy number of worsens sepsis by inducing endothelial pyroptosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718392 DOI: 10.1073/pnas.1812947116  0.52
2018 Guo Y, Zhang N, Zhang D, Ren Q, Ganz T, Liu S, Nemeth E. Iron homeostasis in pregnancy and spontaneous abortion. American Journal of Hematology. PMID 30394565 DOI: 10.1002/ajh.25341  0.52
2018 Gagliano-Jucá T, Pencina KM, Ganz T, Travison TG, Kantoff PW, Nguyen PL, Taplin ME, Kibel AS, Li Z, Huang G, Edwards RR, Nemeth E, Basaria S. Mechanisms Responsible for Reduced Erythropoiesis during Androgen Deprivation Therapy in Men with Prostate Cancer. American Journal of Physiology. Endocrinology and Metabolism. PMID 30325657 DOI: 10.1152/ajpendo.00272.2018  0.52
2018 Coffey R, Sardo U, Kautz L, Gabayan V, Nemeth E, Ganz T. Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice. Physiological Reports. 6: e13890. PMID 30315639 DOI: 10.14814/phy2.13890  0.52
2018 Deshpande CN, Ruwe TA, Shawki A, Xin V, Vieth KR, Valore EV, Qiao B, Ganz T, Nemeth E, Mackenzie B, Jormakka M. Calcium is an essential cofactor for metal efflux by the ferroportin transporter family. Nature Communications. 9: 3075. PMID 30082682 DOI: 10.1038/s41467-018-05446-4  0.52
2018 Hanudel MR, Eisenga MF, Rappaport M, Chua K, Qiao B, Jung G, Gabayan V, Gales B, Ramos G, de Jong MA, van Zanden JJ, de Borst MH, Bakker SJL, Nemeth E, Salusky IB, et al. Effects of erythropoietin on fibroblast growth factor 23 in mice and humans. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. PMID 30007314 DOI: 10.1093/ndt/gfy189  0.52
2018 Stefanova D, Raychev A, Deville J, Humphries R, Campeau S, Ruchala P, Nemeth E, Ganz T, Bulut Y. Hepcidin protects against lethal sepsis in mice inoculated with isolates from septic patients. Infection and Immunity. PMID 29735522 DOI: 10.1128/IAI.00253-18  0.52
2018 Meznarich JA, Draper L, Christensen RD, Yaish HM, Luem ND, Pysher TJ, Jung G, Nemeth E, Ganz T, Ward DM. Fetal presentation of congenital dyserythropoietic anemia type 1 with novel compound heterozygous CDAN1 mutations. Blood Cells, Molecules & Diseases. PMID 29599085 DOI: 10.1016/j.bcmd.2018.03.002  0.52
2018 Adams P, Altes A, Brissot P, Butzeck B, Cabantchik I, Cançado R, Distante S, Evans P, Evans R, Ganz T, Girelli D, Hultcrantz R, McLaren G, Marris B, Milman N, ... Nemeth E, et al. Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype. Hepatology International. PMID 29589198 DOI: 10.1007/s12072-018-9855-0  0.52
2018 Hanudel MR, Rappaport M, Chua K, Gabayan V, Qiao B, Jung G, Salusky IB, Ganz T, Nemeth E. Levels of the erythropoietin-responsive hormone erythroferrone in mice and humans with chronic kidney disease. Haematologica. PMID 29419424 DOI: 10.3324/haematol.2017.181743  0.52
2017 Aschemeyer S, Qiao B, Stefanova D, Valore EV, Sek AC, Ruwe TA, Vieth KR, Jung G, Casu C, Rivella S, Jormakka M, Mackenzie B, Ganz T, Nemeth E. Structure-function analysis of ferroportin defines the binding site and an alternative mechanism of action of hepcidin. Blood. PMID 29237594 DOI: 10.1182/blood-2017-05-786590  0.52
2017 Clinkenbeard EL, Hanudel MR, Stayrook KR, Appaiah HN, Farrow EG, Cass TA, Summers LJ, Ip CS, Hum JM, Thomas JC, Ivan M, Richine BM, Chan RJ, Clemens TL, Schipani E, ... ... Nemeth E, et al. Erythropoietin stimulates murine and human Fibroblast growth factor-23, revealing novel roles for bone and bone marrow. Haematologica. PMID 28818868 DOI: 10.3324/haematol.2017.167882  0.52
2017 McLachlan S, Page KE, Lee SM, Loguinov A, Valore E, Hui ST, Jung G, Zhou J, Lusis AJ, Fuqua B, Ganz T, Nemeth E, Vulpe CD. Hamp1 mRNA and plasma hepcidin levels are influenced by sex and strain but don't predict tissue iron levels in inbred mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00307.2016. PMID 28798083 DOI: 10.1152/ajpgi.00307.2016  0.52
2017 Ganz T, Jung G, Naeim A, Ginzburg Y, Pakbaz Z, Walter PB, Kautz L, Nemeth E. Immunoassay for human serum erythroferrone. Blood. PMID 28739636 DOI: 10.1182/blood-2017-04-777987  0.52
2017 Stefanova D, Raychev A, Arezes J, Ruchala P, Gabayan V, Skurnik M, Dillon BJ, Horwitz MA, Ganz T, Bulut Y, Nemeth E. Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non-transferrin-bound iron. Blood. PMID 28465342 DOI: 10.1182/blood-2017-03-772715  0.52
2017 Khorramian E, Fung E, Chua K, Gabayan V, Ganz T, Nemeth E, Kim A. In a Mouse Model of Sepsis, Hepcidin Ablation Ameliorates Anemia More Effectively Than Iron and Erythropoietin Treatment. Shock (Augusta, Ga.). PMID 28452907 DOI: 10.1097/SHK.0000000000000886  0.52
2017 Michels KR, Zhang Z, Bettina AM, Cagnina RE, Stefanova D, Burdick MD, Vaulont S, Nemeth E, Ganz T, Mehrad B. Hepcidin-mediated iron sequestration protects against bacterial dissemination during pneumonia. Jci Insight. 2: e92002. PMID 28352667 DOI: 10.1172/jci.insight.92002  0.52
2017 Aschemeyer S, Gabayan V, Ganz T, Nemeth E, Kautz L. Erythroferrone and matriptase-2 independently regulate hepcidin expression. American Journal of Hematology. PMID 28187515 DOI: 10.1002/ajh.24672  0.52
2016 Hanudel MR, Rappaport M, Gabayan V, Jung G, Salusky IB, Nemeth E, Ganz T, Zaritsky J. Increased serum hepcidin contributes to the anemia of chronic kidney disease in a murine model. Haematologica. PMID 27884972 DOI: 10.3324/haematol.2016.150433  0.52
2016 Hanudel MR, Chua K, Rappaport M, Gabayan V, Valore E, Goltzman D, Ganz T, Nemeth E, Salusky IB. Effects of Dietary Iron Intake and Chronic Kidney Disease on Fibroblast Growth Factor 23 Metabolism in Wild Type and Hepcidin Knockout Mice. American Journal of Physiology. Renal Physiology. ajprenal.00281.2016. PMID 27733366 DOI: 10.1152/ajprenal.00281.2016  0.52
2016 Ganz T, Nemeth E. Iron Balance and the Role of Hepcidin in Chronic Kidney Disease. Seminars in Nephrology. 36: 87-93. PMID 27236128 DOI: 10.1016/j.semnephrol.2016.02.001  0.52
2016 Casu C, Oikonomidou PR, Chen H, Nandi V, Ginzburg Y, Prasad P, Fleming RE, Shah YM, Valore EV, Nemeth E, Ganz T, MacDonald B, Rivella S. Minihepcidin peptides as disease modifiers in mice affected by β-thalassemia and polycythemia vera. Blood. PMID 27154187 DOI: 10.1182/blood-2015-10-676742  0.52
2016 Kim A, Fung E, Parikh SG, Gabayan V, Nemeth E, Ganz T. Isocitrate treatment of acute anemia of inflammation in a mouse model. Blood Cells, Molecules & Diseases. 56: 31-6. PMID 26603720 DOI: 10.1016/j.bcmd.2015.09.007  0.52
2015 Drakesmith H, Nemeth E, Ganz T. Ironing out Ferroportin. Cell Metabolism. 22: 777-87. PMID 26437604 DOI: 10.1016/j.cmet.2015.09.006  0.52
2015 Michels K, Nemeth E, Ganz T, Mehrad B. Hepcidin and Host Defense against Infectious Diseases. Plos Pathogens. 11: e1004998. PMID 26291319 DOI: 10.1371/journal.ppat.1004998  0.52
2015 Kautz L, Jung G, Du X, Gabayan V, Chapman J, Nasoff M, Nemeth E, Ganz T. Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia. Blood. PMID 26276665 DOI: 10.1182/blood-2015-07-658419  0.52
2015 Ganz T, Nemeth E. Iron homeostasis in host defence and inflammation. Nature Reviews. Immunology. 15: 500-10. PMID 26160612 DOI: 10.1038/nri3863  0.52
2015 Arezes J, Nemeth E. Hepcidin and iron disorders: new biology and clinical approaches. International Journal of Laboratory Hematology. 37: 92-8. PMID 25976966 DOI: 10.1111/ijlh.12358  0.52
2015 Chua K, Fung E, Micewicz ED, Ganz T, Nemeth E, Ruchala P. Small cyclic agonists of iron regulatory hormone hepcidin. Bioorganic & Medicinal Chemistry Letters. PMID 25813158 DOI: 10.1016/j.bmcl.2015.03.012  0.52
2015 Keel SB, Doty R, Liu L, Nemeth E, Cherian S, Ganz T, Abkowitz JL. Evidence that the expression of transferrin receptor 1 on erythroid marrow cells mediates hepcidin suppression in the liver. Experimental Hematology. 43: 469-478.e6. PMID 25782630 DOI: 10.1016/j.exphem.2015.03.001  0.52
2015 Kim A, Nemeth E. New insights into iron regulation and erythropoiesis. Current Opinion in Hematology. 22: 199-205. PMID 25710710 DOI: 10.1097/MOH.0000000000000132  0.52
2015 Fung E, Chua K, Ganz T, Nemeth E, Ruchala P. Thiol-derivatized minihepcidins retain biological activity. Bioorganic & Medicinal Chemistry Letters. 25: 763-6. PMID 25599838 DOI: 10.1016/j.bmcl.2014.12.094  0.52
2015 Arezes J, Jung G, Gabayan V, Valore E, Ruchala P, Gulig PA, Ganz T, Nemeth E, Bulut Y. Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus. Cell Host & Microbe. 17: 47-57. PMID 25590758 DOI: 10.1016/j.chom.2014.12.001  0.52
2015 Gutschow P, Schmidt PJ, Han H, Ostland V, Bartnikas TB, Pettiglio MA, Herrera C, Butler JS, Nemeth E, Ganz T, Fleming MD, Westerman M. A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis. Haematologica. 100: 167-77. PMID 25425686 DOI: 10.3324/haematol.2014.116723  0.52
2014 Kautz L, Jung G, Nemeth E, Ganz T. Erythroferrone contributes to recovery from anemia of inflammation. Blood. 124: 2569-74. PMID 25193872 DOI: 10.1182/blood-2014-06-584607  0.52
2014 Zhang S, Chen Y, Guo W, Yuan L, Zhang D, Xu Y, Nemeth E, Ganz T, Liu S. Disordered hepcidin-ferroportin signaling promotes breast cancer growth. Cellular Signalling. 26: 2539-50. PMID 25093806 DOI: 10.1016/j.cellsig.2014.07.029  0.52
2014 Koenig MD, Tussing-Humphreys L, Day J, Cadwell B, Nemeth E. Hepcidin and iron homeostasis during pregnancy. Nutrients. 6: 3062-83. PMID 25093277 DOI: 10.3390/nu6083062  0.52
2014 Nemeth E, Ganz T. Anemia of inflammation. Hematology/Oncology Clinics of North America. 28: 671-81, vi. PMID 25064707 DOI: 10.1016/j.hoc.2014.04.005  0.52
2014 Kautz L, Jung G, Valore EV, Rivella S, Nemeth E, Ganz T. Identification of erythroferrone as an erythroid regulator of iron metabolism. Nature Genetics. 46: 678-84. PMID 24880340 DOI: 10.1038/ng.2996  0.52
2014 Kautz L, Nemeth E. Molecular liaisons between erythropoiesis and iron metabolism. Blood. 124: 479-82. PMID 24876565 DOI: 10.1182/blood-2014-05-516252  0.52
2014 Pusatcioglu CK, Nemeth E, Fantuzzi G, Llor X, Freels S, Tussing-Humphreys L, Cabay RJ, Linzmeier R, Ng D, Clark J, Braunschweig C. Systemic and tumor level iron regulation in men with colorectal cancer: a case control study. Nutrition & Metabolism. 11: 21. PMID 24872837 DOI: 10.1186/1743-7075-11-21  0.52
2014 Kim A, Rivera S, Shprung D, Limbrick D, Gabayan V, Nemeth E, Ganz T. Mouse models of anemia of cancer. Plos One. 9: e93283. PMID 24681760 DOI: 10.1371/journal.pone.0093283  0.52
2014 Dekan Z, Mobli M, Pennington MW, Fung E, Nemeth E, Alewood PF. Total synthesis of human hepcidin through regioselective disulfide-bond formation by using the safety-catch cysteine protecting group 4,4'-dimethylsulfinylbenzhydryl. Angewandte Chemie (International Ed. in English). 53: 2931-4. PMID 24604812 DOI: 10.1002/anie.201310103  0.52
2014 Ruchala P, Nemeth E. The pathophysiology and pharmacology of hepcidin. Trends in Pharmacological Sciences. 35: 155-61. PMID 24552640 DOI: 10.1016/j.tips.2014.01.004  0.52
2014 Rodriguez R, Jung CL, Gabayan V, Deng JC, Ganz T, Nemeth E, Bulut Y. Hepcidin induction by pathogens and pathogen-derived molecules is strongly dependent on interleukin-6. Infection and Immunity. 82: 745-52. PMID 24478088 DOI: 10.1128/IAI.00983-13  0.52
2014 Kim A, Fung E, Parikh SG, Valore EV, Gabayan V, Nemeth E, Ganz T. A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin. Blood. 123: 1129-36. PMID 24357728 DOI: 10.1182/blood-2013-08-521419  0.52
2014 Mitchell CJ, Shawki A, Ganz T, Nemeth E, Mackenzie B. Functional properties of human ferroportin, a cellular iron exporter reactive also with cobalt and zinc. American Journal of Physiology. Cell Physiology. 306: C450-9. PMID 24304836 DOI: 10.1152/ajpcell.00348.2013  0.52
2013 Kautz L, Gabayan V, Wang X, Wu J, Onwuzurike J, Jung G, Qiao B, Lusis AJ, Ganz T, Nemeth E. Testing the iron hypothesis in a mouse model of atherosclerosis. Cell Reports. 5: 1436-42. PMID 24316081 DOI: 10.1016/j.celrep.2013.11.009  0.52
2013 Fung E, Nemeth E. Manipulation of the hepcidin pathway for therapeutic purposes. Haematologica. 98: 1667-76. PMID 24186312 DOI: 10.3324/haematol.2013.084624  0.52
2013 Nemeth E. Anti-hepcidin therapy for iron-restricted anemias. Blood. 122: 2929-31. PMID 24159166 DOI: 10.1182/blood-2013-08-522466  0.52
2013 Clark RJ, Preza GC, Tan CC, van Dijk JW, Fung E, Nemeth E, Ganz T, Craik DJ. Design, synthesis, and characterization of cyclic analogues of the iron regulatory peptide hormone hepcidin. Biopolymers. 100: 519-26. PMID 23897622 DOI: 10.1002/bip.22350  0.52
2013 Nemeth E. Hepcidin and β-thalassemia major. Blood. 122: 3-4. PMID 23828883 DOI: 10.1182/blood-2013-05-502617  0.52
2013 Preza GC, Pinon R, Ganz T, Nemeth E. Cellular catabolism of the iron-regulatory peptide hormone hepcidin. Plos One. 8: e58934. PMID 23536837 DOI: 10.1371/journal.pone.0058934  0.52
2013 Mast AE, Schlumpf KS, Wright DJ, Johnson B, Glynn SA, Busch MP, Olbina G, Westerman M, Nemeth E, Ganz T. Hepcidin level predicts hemoglobin concentration in individuals undergoing repeated phlebotomy. Haematologica. 98: 1324-30. PMID 23445875 DOI: 10.3324/haematol.2012.070979  0.52
2013 Guo W, Bachman E, Li M, Roy CN, Blusztajn J, Wong S, Chan SY, Serra C, Jasuja R, Travison TG, Muckenthaler MU, Nemeth E, Bhasin S. Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells. Aging Cell. 12: 280-91. PMID 23399021 DOI: 10.1111/acel.12052  0.52
2013 Fung E, Sugianto P, Hsu J, Damoiseaux R, Ganz T, Nemeth E. High-throughput screening of small molecules identifies hepcidin antagonists. Molecular Pharmacology. 83: 681-90. PMID 23292796 DOI: 10.1124/mol.112.083428  0.52
2013 Basseri RJ, Nemeth E, Vassilaki ME, Basseri B, Enayati P, Shaye O, Bourikas LA, Ganz T, Papadakis KA. Hepcidin is a key mediator of anemia of inflammation in Crohn's disease. Journal of Crohn's & Colitis. 7: e286-91. PMID 23219355 DOI: 10.1016/j.crohns.2012.10.013  0.52
2012 Ganz T, Goff J, Klasing K, Nemeth E, Roth T. IOD in rhinos--immunity group report: report from the Immunity, Genetics and Toxicology Working Group of the International Workshop on Iron Overload Disorder in Browsing Rhinoceros (February 2011). Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians. 43: S117-9. PMID 23156715 DOI: 10.1638/1042-7260-43.3s.S117  0.52
2012 Ganz T, Nemeth E. Iron homeostasis and its disorders in mice and men: potential lessons for rhinos. Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians. 43: S19-26. PMID 23156702 DOI: 10.1638/2011-0158.1  0.52
2012 Ramos E, Ruchala P, Goodnough JB, Kautz L, Preza GC, Nemeth E, Ganz T. Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis. Blood. 120: 3829-36. PMID 22990014 DOI: 10.1182/blood-2012-07-440743  0.52
2012 Tussing-Humphreys L, Pusatcioglu C, Pustacioglu C, Nemeth E, Braunschweig C. Rethinking iron regulation and assessment in iron deficiency, anemia of chronic disease, and obesity: introducing hepcidin. Journal of the Academy of Nutrition and Dietetics. 112: 391-400. PMID 22717199 DOI: 10.1016/j.jada.2011.08.038  0.52
2012 Qiao B, Sugianto P, Fung E, Del-Castillo-Rueda A, Moran-Jimenez MJ, Ganz T, Nemeth E. Hepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitination. Cell Metabolism. 15: 918-24. PMID 22682227 DOI: 10.1016/j.cmet.2012.03.018  0.52
2012 Ross SL, Tran L, Winters A, Lee KJ, Plewa C, Foltz I, King C, Miranda LP, Allen J, Beckman H, Cooke KS, Moody G, Sasu BJ, Nemeth E, Ganz T, et al. Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAK-STAT. Cell Metabolism. 15: 905-17. PMID 22682226 DOI: 10.1016/j.cmet.2012.03.017  0.52
2012 Ravasi G, Pelucchi S, Trombini P, Mariani R, Tomosugi N, Modignani GL, Pozzi M, Nemeth E, Ganz T, Hayashi H, Barisani D, Piperno A. Hepcidin expression in iron overload diseases is variably modulated by circulating factors. Plos One. 7: e36425. PMID 22586470 DOI: 10.1371/journal.pone.0036425  0.52
2012 Ganz T, Nemeth E. Iron metabolism: interactions with normal and disordered erythropoiesis. Cold Spring Harbor Perspectives in Medicine. 2: a011668. PMID 22553501 DOI: 10.1101/cshperspect.a011668  0.52
2012 Ganz T, Nemeth E. Hepcidin and iron homeostasis. Biochimica Et Biophysica Acta. 1823: 1434-43. PMID 22306005 DOI: 10.1016/j.bbamcr.2012.01.014  0.52
2012 Goodnough JB, Ramos E, Nemeth E, Ganz T. Inhibition of hepcidin transcription by growth factors. Hepatology (Baltimore, Md.). 56: 291-9. PMID 22278715 DOI: 10.1002/hep.25615  0.52
2011 Ganz T, Nemeth E. The hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disorders. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2011: 538-42. PMID 22160086 DOI: 10.1182/asheducation-2011.1.538  0.52
2011 Tussing-Humphreys L, Frayn KN, Smith SR, Westerman M, Dennis AL, Nemeth E, Thomson J, Pusatcioglu C. Subcutaneous adipose tissue from obese and lean adults does not release hepcidin in vivo. Thescientificworldjournal. 11: 2197-206. PMID 22125467 DOI: 10.1100/2011/634861  0.52
2011 Preza GC, Ruchala P, Pinon R, Ramos E, Qiao B, Peralta MA, Sharma S, Waring A, Ganz T, Nemeth E. Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload. The Journal of Clinical Investigation. 121: 4880-8. PMID 22045566 DOI: 10.1172/JCI57693  0.52
2011 Trombini P, Paolini V, Pelucchi S, Mariani R, Nemeth E, Ganz T, Piperno A. Hepcidin response to acute iron intake and chronic iron loading in dysmetabolic iron overload syndrome. Liver International : Official Journal of the International Association For the Study of the Liver. 31: 994-1000. PMID 21733088 DOI: 10.1111/j.1478-3231.2011.02520.x  0.52
2011 Pasricha SR, McQuilten Z, Westerman M, Keller A, Nemeth E, Ganz T, Wood E. Serum hepcidin as a diagnostic test of iron deficiency in premenopausal female blood donors. Haematologica. 96: 1099-105. PMID 21508121 DOI: 10.3324/haematol.2010.037960  0.52
2011 Ramos E, Kautz L, Rodriguez R, Hansen M, Gabayan V, Ginzburg Y, Roth MP, Nemeth E, Ganz T. Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice. Hepatology (Baltimore, Md.). 53: 1333-41. PMID 21480335 DOI: 10.1002/hep.24178  0.52
2011 Clark RJ, Tan CC, Preza GC, Nemeth E, Ganz T, Craik DJ. Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chemistry & Biology. 18: 336-43. PMID 21439478 DOI: 10.1016/j.chembiol.2010.12.009  0.52
2011 Girelli D, Trombini P, Busti F, Campostrini N, Sandri M, Pelucchi S, Westerman M, Ganz T, Nemeth E, Piperno A, Camaschella C. A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis. Haematologica. 96: 500-6. PMID 21173098 DOI: 10.3324/haematol.2010.033449  0.52
2011 Ganz T, Nemeth E. Hepcidin and disorders of iron metabolism. Annual Review of Medicine. 62: 347-60. PMID 20887198 DOI: 10.1146/annurev-med-050109-142444  0.52
2011 Burpee T, Mitchell P, Fishman D, Islam S, Nemeth E, Westerman M, Wessling-Resnick M, Grand RJ. Intestinal ferroportin expression in pediatric Crohn's disease. Inflammatory Bowel Diseases. 17: 524-31. PMID 20564534 DOI: 10.1002/ibd.21367  0.52
2010 Kautz L, Nemeth E. Novel tools for the evaluation of iron metabolism. Haematologica. 95: 1989-91. PMID 21123438 DOI: 10.3324/haematol.2010.033993  0.52
2010 Gardenghi S, Ramos P, Marongiu MF, Melchiori L, Breda L, Guy E, Muirhead K, Rao N, Roy CN, Andrews NC, Nemeth E, Follenzi A, An X, Mohandas N, Ginzburg Y, et al. Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice. The Journal of Clinical Investigation. 120: 4466-77. PMID 21099112 DOI: 10.1172/JCI41717  0.52
2010 Nemeth E. Hepcidin biology and therapeutic applications. Expert Review of Hematology. 3: 153-5. PMID 21083458 DOI: 10.1586/ehm.10.1  0.52
2010 Rivella S, Nemeth E, Miller JL. Crosstalk between Erythropoiesis and Iron Metabolism. Advances in Hematology. 2010. PMID 20862206 DOI: 10.1155/2010/317095  0.52
2010 Goodnough LT, Nemeth E, Ganz T. Detection, evaluation, and management of iron-restricted erythropoiesis. Blood. 116: 4754-61. PMID 20826717 DOI: 10.1182/blood-2010-05-286260  0.52
2010 Nemeth E. Hepcidin in beta-thalassemia. Annals of the New York Academy of Sciences. 1202: 31-5. PMID 20712769 DOI: 10.1111/j.1749-6632.2010.05585.x  0.52
2010 Maes K, Nemeth E, Roodman GD, Huston A, Esteve F, Freytes C, Callander N, Katodritou E, Tussing-Humphreys L, Rivera S, Vanderkerken K, Lichtenstein A, Ganz T. In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2. Blood. 116: 3635-44. PMID 20679527 DOI: 10.1182/blood-2010-03-274571  0.52
2010 Ayoya MA, Spiekermann-Brouwer GM, Stoltzfus RJ, Nemeth E, Habicht JP, Ganz T, Rawat R, Traoré AK, Garza C. Alpha 1-acid glycoprotein, hepcidin, C-reactive protein, and serum ferritin are correlated in anemic schoolchildren with Schistosoma haematobium. The American Journal of Clinical Nutrition. 91: 1784-90. PMID 20410090 DOI: 10.3945/ajcn.2010.29353  0.52
2010 Zaritsky J, Young B, Gales B, Wang HJ, Rastogi A, Westerman M, Nemeth E, Ganz T, Salusky IB. Reduction of serum hepcidin by hemodialysis in pediatric and adult patients. Clinical Journal of the American Society of Nephrology : Cjasn. 5: 1010-4. PMID 20299375 DOI: 10.2215/CJN.08161109  0.52
2010 Ferrucci L, Semba RD, Guralnik JM, Ershler WB, Bandinelli S, Patel KV, Sun K, Woodman RC, Andrews NC, Cotter RJ, Ganz T, Nemeth E, Longo DL. Proinflammatory state, hepcidin, and anemia in older persons. Blood. 115: 3810-6. PMID 20081092 DOI: 10.1182/blood-2009-02-201087  0.52
2010 Tussing-Humphreys LM, Nemeth E, Fantuzzi G, Freels S, Holterman AX, Galvani C, Ayloo S, Vitello J, Braunschweig C. Decreased serum hepcidin and improved functional iron status 6 months after restrictive bariatric surgery. Obesity (Silver Spring, Md.). 18: 2010-6. PMID 20075851 DOI: 10.1038/oby.2009.490  0.52
2010 Nemeth E. Targeting the hepcidin-ferroportin axis in the diagnosis and treatment of anemias. Advances in Hematology. 2010: 750643. PMID 20066043 DOI: 10.1155/2010/750643  0.52
2010 Tussing-Humphreys LM, Nemeth E, Fantuzzi G, Freels S, Guzman G, Holterman AX, Braunschweig C. Elevated systemic hepcidin and iron depletion in obese premenopausal females. Obesity (Silver Spring, Md.). 18: 1449-56. PMID 19816411 DOI: 10.1038/oby.2009.319  0.52
2010 Westerman ME, Olbina G, Ostland VE, Nemeth E, Ganz T. Hepcidin: An emerging biomarker for iron disorders, inflammatory diseases, and infections Proceedings of Spie - the International Society For Optical Engineering. 7666. DOI: 10.1117/12.854910  0.52
2009 Ayoya MA, Stoltzfus RJ, Spiekermann-Brouwer GM, Nemeth E, Traoré AK, Ganz T, Garza C. [Hepcidin and Plasmodium falciparum malaria in anemic school children in Mali]. Bulletin De La SociéTé De Pathologie Exotique (1990). 102: 219-20. PMID 19950537 DOI: 10.3185/pathexo3406  0.52
2009 Nemeth E, Ganz T. The role of hepcidin in iron metabolism. Acta Haematologica. 122: 78-86. PMID 19907144 DOI: 10.1159/000243791  0.52
2009 Ganz T, Nemeth E. Iron sequestration and anemia of inflammation. Seminars in Hematology. 46: 387-93. PMID 19786207 DOI: 10.1053/j.seminhematol.2009.06.001  0.52
2009 Girelli D, Pasino M, Goodnough JB, Nemeth E, Guido M, Castagna A, Busti F, Campostrini N, Martinelli N, Vantini I, Corrocher R, Ganz T, Fattovich G. Reduced serum hepcidin levels in patients with chronic hepatitis C. Journal of Hepatology. 51: 845-52. PMID 19729219 DOI: 10.1016/j.jhep.2009.06.027  0.52
2009 Sham RL, Phatak PD, Nemeth E, Ganz T. Hereditary hemochromatosis due to resistance to hepcidin: high hepcidin concentrations in a family with C326S ferroportin mutation. Blood. 114: 493-4. PMID 19589941 DOI: 10.1182/blood-2009-04-216226  0.52
2009 Zaritsky J, Young B, Wang HJ, Westerman M, Olbina G, Nemeth E, Ganz T, Rivera S, Nissenson AR, Salusky IB. Hepcidin--a potential novel biomarker for iron status in chronic kidney disease. Clinical Journal of the American Society of Nephrology : Cjasn. 4: 1051-6. PMID 19406957 DOI: 10.2215/CJN.05931108  0.52
2009 Ruivard M, Lainé F, Ganz T, Olbina G, Westerman M, Nemeth E, Rambeau M, Mazur A, Gerbaud L, Tournilhac V, Abergel A, Philippe P, Deugnier Y, Coudray C. Iron absorption in dysmetabolic iron overload syndrome is decreased and correlates with increased plasma hepcidin. Journal of Hepatology. 50: 1219-25. PMID 19398238 DOI: 10.1016/j.jhep.2009.01.029  0.52
2009 Fernandes A, Preza GC, Phung Y, De Domenico I, Kaplan J, Ganz T, Nemeth E. The molecular basis of hepcidin-resistant hereditary hemochromatosis. Blood. 114: 437-43. PMID 19383972 DOI: 10.1182/blood-2008-03-146134  0.52
2009 Troadec MB, Lainé F, Daniel V, Rochcongar P, Ropert M, Cabillic F, Perrin M, Morcet J, Loréal O, Olbina G, Westerman M, Nemeth E, Ganz T, Brissot P. Daily regulation of serum and urinary hepcidin is not influenced by submaximal cycling exercise in humans with normal iron metabolism. European Journal of Applied Physiology. 106: 435-43. PMID 19306018 DOI: 10.1007/s00421-009-1031-8  0.52
2009 Tussing-Humphreys LM, Liang H, Nemeth E, Freels S, Braunschweig CA. Excess adiposity, inflammation, and iron-deficiency in female adolescents. Journal of the American Dietetic Association. 109: 297-302. PMID 19167957 DOI: 10.1016/j.jada.2008.10.044  0.52
2008 Ganz T, Olbina G, Girelli D, Nemeth E, Westerman M. Immunoassay for human serum hepcidin. Blood. 112: 4292-7. PMID 18689548 DOI: 10.1182/blood-2008-02-139915  0.52
2008 De Domenico I, Nemeth E, Nelson JM, Phillips JD, Ajioka RS, Kay MS, Kushner JP, Ganz T, Ward DM, Kaplan J. The hepcidin-binding site on ferroportin is evolutionarily conserved. Cell Metabolism. 8: 146-56. PMID 18680715 DOI: 10.1016/j.cmet.2008.07.002  0.52
2008 Sharma S, Nemeth E, Chen YH, Goodnough J, Huston A, Roodman GD, Ganz T, Lichtenstein A. Involvement of hepcidin in the anemia of multiple myeloma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3262-7. PMID 18519751 DOI: 10.1158/1078-0432.CCR-07-4153  0.52
2008 Winder A, Lefkowitz R, Ghoti H, Leiba M, Ganz T, Nemeth E, Rachmilewitz EA. Urinary hepcidin excretion in patients with myelodysplastic syndrome and myelofibrosis. British Journal of Haematology. 142: 669-71. PMID 18498424 DOI: 10.1111/j.1365-2141.2008.07225.x  0.52
2008 Barisani D, Pelucchi S, Mariani R, Galimberti S, Trombini P, Fumagalli D, Meneveri R, Nemeth E, Ganz T, Piperno A. Hepcidin and iron-related gene expression in subjects with Dysmetabolic Hepatic Iron Overload. Journal of Hepatology. 49: 123-33. PMID 18462824 DOI: 10.1016/j.jhep.2008.03.011  0.52
2008 Nemeth E. Iron regulation and erythropoiesis. Current Opinion in Hematology. 15: 169-75. PMID 18391780 DOI: 10.1097/MOH.0b013e3282f73335  0.52
2008 Bozzini C, Campostrini N, Trombini P, Nemeth E, Castagna A, Tenuti I, Corrocher R, Camaschella C, Ganz T, Olivieri O, Piperno A, Girelli D. Measurement of urinary hepcidin levels by SELDI-TOF-MS in HFE-hemochromatosis. Blood Cells, Molecules & Diseases. 40: 347-52. PMID 18164223 DOI: 10.1016/j.bcmd.2007.10.001  0.52
2008 Lin L, Nemeth E, Goodnough JB, Thapa DR, Gabayan V, Ganz T. Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site. Blood Cells, Molecules & Diseases. 40: 122-31. PMID 17869549 DOI: 10.1016/j.bcmd.2007.06.023  0.52
2007 Trombini P, Coliva T, Nemeth E, Mariani R, Ganz T, Biondi A, Piperno A. Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemia. Haematologica. 92: 1407-10. PMID 17768112 DOI: 10.3324/haematol.11377  0.52
2007 Piperno A, Girelli D, Nemeth E, Trombini P, Bozzini C, Poggiali E, Phung Y, Ganz T, Camaschella C. Blunted hepcidin response to oral iron challenge in HFE-related hemochromatosis. Blood. 110: 4096-100. PMID 17724144 DOI: 10.1182/blood-2007-06-096503  0.52
2007 Lin L, Valore EV, Nemeth E, Goodnough JB, Gabayan V, Ganz T. Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4. Blood. 110: 2182-9. PMID 17540841 DOI: 10.1182/blood-2007-04-087593  0.52
2007 Origa R, Galanello R, Ganz T, Giagu N, Maccioni L, Faa G, Nemeth E. Liver iron concentrations and urinary hepcidin in beta-thalassemia. Haematologica. 92: 583-8. PMID 17488680 DOI: 10.3324/haematol.10842  0.52
2007 De Domenico I, Ward DM, Langelier C, Vaughn MB, Nemeth E, Sundquist WI, Ganz T, Musci G, Kaplan J. The molecular mechanism of hepcidin-mediated ferroportin down-regulation. Molecular Biology of the Cell. 18: 2569-78. PMID 17475779 DOI: 10.1091/mbc.E07-01-0060  0.52
2007 Kearney SL, Nemeth E, Neufeld EJ, Thapa D, Ganz T, Weinstein DA, Cunningham MJ. Urinary hepcidin in congenital chronic anemias. Pediatric Blood & Cancer. 48: 57-63. PMID 16220548 DOI: 10.1002/pbc.20616  0.52
2007 Nemeth E, Ganz T. Iron and aging Blood Disorders in the Elderly. 171-180. DOI: 10.1017/CBO9780511545238.014  0.52
2006 Semrin G, Fishman DS, Bousvaros A, Zholudev A, Saunders AC, Correia CE, Nemeth E, Grand RJ, Weinstein DA. Impaired intestinal iron absorption in Crohn's disease correlates with disease activity and markers of inflammation. Inflammatory Bowel Diseases. 12: 1101-6. PMID 17119383 DOI: 10.1097/01.mib.0000235097.86360.04  0.52
2006 De Domenico I, McVey Ward D, Nemeth E, Ganz T, Corradini E, Ferrara F, Musci G, Pietrangelo A, Kaplan J. Molecular and clinical correlates in iron overload associated with mutations in ferroportin. Haematologica. 91: 1092-5. PMID 16885049  0.52
2006 Nemeth E, Ganz T. Regulation of iron metabolism by hepcidin. Annual Review of Nutrition. 26: 323-42. PMID 16848710 DOI: 10.1146/annurev.nutr.26.061505.111303  0.52
2006 Pospisilova D, Mims MP, Nemeth E, Ganz T, Prchal JT. DMT1 mutation: response of anemia to darbepoetin administration and implications for iron homeostasis. Blood. 108: 404-5. PMID 16790587 DOI: 10.1182/blood-2006-02-003962  0.52
2006 Ganz T, Nemeth E. Regulation of iron acquisition and iron distribution in mammals. Biochimica Et Biophysica Acta. 1763: 690-9. PMID 16790283 DOI: 10.1016/j.bbamcr.2006.03.014  0.52
2006 Nemeth E, Ganz T. Hepcidin and iron-loading anemias. Haematologica. 91: 727-32. PMID 16769573  0.52
2006 Ganz T, Nemeth E. Iron imports. IV. Hepcidin and regulation of body iron metabolism. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G199-203. PMID 16407589 DOI: 10.1152/ajpgi.00412.2005  0.52
2006 Nemeth E, Preza GC, Jung CL, Kaplan J, Waring AJ, Ganz T. The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study. Blood. 107: 328-33. PMID 16141345 DOI: 10.1182/blood-2005-05-2049  0.52
2005 Roecker L, Meier-Buttermilch R, Brechtel L, Nemeth E, Ganz T. Iron-regulatory protein hepcidin is increased in female athletes after a marathon. European Journal of Applied Physiology. 95: 569-71. PMID 16249921 DOI: 10.1007/s00421-005-0055-y  0.52
2005 Porto G, Roetto A, Daraio F, Pinto JP, Almeida S, Bacelar C, Nemeth E, Ganz T, Camaschella C. A Portuguese patient homozygous for the -25G>A mutation of the HAMP promoter shows evidence of steady-state transcription but fails to up-regulate hepcidin levels by iron. Blood. 106: 2922-3. PMID 16204153 DOI: 10.1182/blood-2005-04-1630  0.52
2005 Kemna E, Tjalsma H, Laarakkers C, Nemeth E, Willems H, Swinkels D. Novel urine hepcidin assay by mass spectrometry. Blood. 106: 3268-70. PMID 16030189 DOI: 10.1182/blood-2005-05-1873  0.52
2005 Zoller H, McFarlane I, Theurl I, Stadlmann S, Nemeth E, Oxley D, Ganz T, Halsall DJ, Cox TM, Vogel W. Primary iron overload with inappropriate hepcidin expression in V162del ferroportin disease. Hepatology (Baltimore, Md.). 42: 466-72. PMID 15986403 DOI: 10.1002/hep.20775  0.52
2005 De Domenico I, Ward DM, Nemeth E, Vaughn MB, Musci G, Ganz T, Kaplan J. The molecular basis of ferroportin-linked hemochromatosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 8955-60. PMID 15956209 DOI: 10.1073/pnas.0503804102  0.52
2005 Rivera S, Nemeth E, Gabayan V, Lopez MA, Farshidi D, Ganz T. Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs. Blood. 106: 2196-9. PMID 15933050 DOI: 10.1182/blood-2005-04-1766  0.52
2005 Détivaud L, Nemeth E, Boudjema K, Turlin B, Troadec MB, Leroyer P, Ropert M, Jacquelinet S, Courselaud B, Ganz T, Brissot P, Loréal O. Hepcidin levels in humans are correlated with hepatic iron stores, hemoglobin levels, and hepatic function. Blood. 106: 746-8. PMID 15797999 DOI: 10.1182/blood-2004-12-4855  0.52
2005 Papanikolaou G, Tzilianos M, Christakis JI, Bogdanos D, Tsimirika K, MacFarlane J, Goldberg YP, Sakellaropoulos N, Ganz T, Nemeth E. Hepcidin in iron overload disorders. Blood. 105: 4103-5. PMID 15671438 DOI: 10.1182/blood-2004-12-4844  0.52
2005 Nemeth E, Roetto A, Garozzo G, Ganz T, Camaschella C. Hepcidin is decreased in TFR2 hemochromatosis. Blood. 105: 1803-6. PMID 15486069 DOI: 10.1182/blood-2004-08-3042  0.52
2005 Rivera S, Liu L, Nemeth E, Gabayan V, Sorensen OE, Ganz T. Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia. Blood. 105: 1797-802. PMID 15479721 DOI: 10.1182/blood-2004-08-3375  0.52
2004 Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science (New York, N.Y.). 306: 2090-3. PMID 15514116 DOI: 10.1126/science.1104742  0.52
2004 Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, Ganz T. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. The Journal of Clinical Investigation. 113: 1271-6. PMID 15124018 DOI: 10.1172/JCI20945  0.52
2004 Papanikolaou G, Samuels ME, Ludwig EH, MacDonald ML, Franchini PL, Dubé MP, Andres L, MacFarlane J, Sakellaropoulos N, Politou M, Nemeth E, Thompson J, Risler JK, Zaborowska C, Babakaiff R, et al. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nature Genetics. 36: 77-82. PMID 14647275 DOI: 10.1038/ng1274  0.52
2003 Nemeth E, Valore EV, Territo M, Schiller G, Lichtenstein A, Ganz T. Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood. 101: 2461-3. PMID 12433676 DOI: 10.1182/blood-2002-10-3235  0.52
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