Walter Bodmer, Ph.D. - Publications

Affiliations: 
Weatherall Institute of Molecular Medicine University of Oxford, Oxford, United Kingdom 
Area:
population genetics, somatic cell hybrids, stem cells

201 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Pødenphant M, Ashley N, Koprowska K, Mir KU, Zalkovskij M, Bilenberg B, Bodmer W, Kristensen A, Marie R. Separation of cancer cells from white blood cells by pinched flow fractionation. Lab On a Chip. PMID 26510401 DOI: 10.1039/C5Lc01014D  0.44
2015 Bodmer W. A Mathematician's Odyssey. Annual Review of Genomics and Human Genetics. 16: 1-29. PMID 25939053 DOI: 10.1146/Annurev-Genom-090314-045856  0.44
2015 Jones MF, Hara T, Francis P, Li XL, Bilke S, Zhu Y, Pineda M, Subramanian M, Bodmer WF, Lal A. The CDX1-microRNA-215 axis regulates colorectal cancer stem cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 112: E1550-8. PMID 25775580 DOI: 10.1073/pnas.1503370112  0.44
2015 Bodmer W. Genetic characterization of human populations: from ABO to a genetic map of the British people. Genetics. 199: 267-79. PMID 25657345 DOI: 10.1534/Genetics.114.173062  0.44
2015 Bodmer W, Winney B. Population Genetics: The study of the genetic structure of human populations Population in the Human Sciences: Concepts, Models, Evidence. DOI: 10.1093/acprof:oso/9780199688203.003.0003  0.44
2014 Gao S, Bajrami I, Verrill C, Kigozi A, Ouaret D, Aleksic T, Asher R, Han C, Allen P, Bailey D, Feller S, Kashima T, Athanasou N, Blay JY, Schmitz S, ... ... Bodmer WF, et al. Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling. Cancer Research. 74: 5866-77. PMID 25168481 DOI: 10.1158/0008-5472.CAN-14-0806  0.44
2014 Vargas G. Biomarkers in schizophrenia. Biomarkers in Medicine. 8: 1-3. PMID 24325218 DOI: 10.2217/bmm.13.138  0.44
2013 Ashley N, Yeung TM, Bodmer WF. Stem cell differentiation and lumen formation in colorectal cancer cell lines and primary tumors. Cancer Research. 73: 5798-809. PMID 23867471 DOI: 10.1158/0008-5472.CAN-13-0454  0.44
2013 Yeung TM, Buskens C, Wang LM, Mortensen NJ, Bodmer WF. Myofibroblast activation in colorectal cancer lymph node metastases. British Journal of Cancer. 108: 2106-15. PMID 23652304 DOI: 10.1038/bjc.2013.209  0.44
2012 Ashraf SQ, Nicholls AM, Wilding JL, Ntouroupi TG, Mortensen NJ, Bodmer WF. Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel. Proceedings of the National Academy of Sciences of the United States of America. 109: 21046-51. PMID 23213241 DOI: 10.1073/pnas.1218750110  0.44
2012 Lefevre JH, Bonilla C, Colas C, Winney B, Johnstone E, Tonks S, Day T, Hutnik K, Boumertit A, Soubrier F, Midgley R, Kerr D, Parc Y, Bodmer WF. Role of rare variants in undetermined multiple adenomatous polyposis and early-onset colorectal cancer. Journal of Human Genetics. 57: 709-16. PMID 22875147 DOI: 10.1038/jhg.2012.99  0.44
2012 Busby GB, Brisighelli F, Sánchez-Diz P, Ramos-Luis E, Martinez-Cadenas C, Thomas MG, Bradley DG, Gusmão L, Winney B, Bodmer W, Vennemann M, Coia V, Scarnicci F, Tofanelli S, Vona G, et al. The peopling of Europe and the cautionary tale of Y chromosome lineage R-M269. Proceedings. Biological Sciences / the Royal Society. 279: 884-92. PMID 21865258 DOI: 10.1098/Rspb.2011.1044  0.44
2012 Winney B, Boumertit A, Day T, Davison D, Echeta C, Evseeva I, Hutnik K, Leslie S, Nicodemus K, Royrvik EC, Tonks S, Yang X, Cheshire J, Longley P, Mateos P, ... ... Bodmer W, et al. People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population. European Journal of Human Genetics : Ejhg. 20: 203-10. PMID 21829225 DOI: 10.1038/Ejhg.2011.127  0.44
2011 Yeung TM, Gandhi SC, Bodmer WF. Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 4382-7. PMID 21368208 DOI: 10.1073/pnas.1014519107  0.44
2011 Bonilla C, Lefèvre JH, Winney B, Johnstone E, Tonks S, Colas C, Day T, Hutnik K, Boumertit A, Midgley R, Kerr D, Parc Y, Bodmer WF. Cyclin D1 rare variants in UK multiple adenoma and early-onset colorectal cancer patients. Journal of Human Genetics. 56: 58-63. PMID 21107342 DOI: 10.1038/jhg.2010.144  0.44
2011 Bodmer WF. The human genome project, then and now Scientist. 25.  0.44
2010 Wilding JL, McGowan S, Liu Y, Bodmer WF. Replication error deficient and proficient colorectal cancer gene expression differences caused by 3'UTR polyT sequence deletions. Proceedings of the National Academy of Sciences of the United States of America. 107: 21058-63. PMID 21097699 DOI: 10.1073/pnas.1015604107  0.44
2010 Johnston MD, Maini PK, Jonathan Chapman S, Edwards CM, Bodmer WF. On the proportion of cancer stem cells in a tumour. Journal of Theoretical Biology. 266: 708-11. PMID 20678505 DOI: 10.1016/j.jtbi.2010.07.031  0.44
2010 Lefevre JH, Colas C, Coulet F, Bonilla C, Mourra N, Flejou JF, Tiret E, Bodmer W, Soubrier F, Parc Y. MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions. Familial Cancer. 9: 589-94. PMID 20640893 DOI: 10.1007/S10689-010-9367-0  0.44
2010 Bracht K, Nicholls AM, Liu Y, Bodmer WF. 5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency. British Journal of Cancer. 103: 340-6. PMID 20606684 DOI: 10.1038/sj.bjc.6605780  0.44
2010 Bodmer W, Tomlinson I. Rare genetic variants and the risk of cancer. Current Opinion in Genetics & Development. 20: 262-7. PMID 20554195 DOI: 10.1016/J.Gde.2010.04.016  0.44
2010 Carvajal-Carmona LG, Churchman M, Bonilla C, Walther A, Lefèvre JH, Kerr D, Dunlop M, Houlston R, Bodmer WF, Tomlinson I. Comprehensive assessment of variation at the transforming growth factor beta type 1 receptor locus and colorectal cancer predisposition. Proceedings of the National Academy of Sciences of the United States of America. 107: 7858-62. PMID 20368424 DOI: 10.1073/pnas.1002816107  0.44
2010 Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Fernández-Viña M, Geraghty DE, Holdsworth R, Hurley CK, Lau M, Lee KW, Mach B, Maiers M, Mayr WR, et al. Nomenclature for factors of the HLA system, 2010. Tissue Antigens. 75: 291-455. PMID 20356336 DOI: 10.1111/J.1399-0039.2010.01466.X  0.44
2010 Evseeva I, Nicodemus KK, Bonilla C, Tonks S, Bodmer WF. Linkage disequilibrium and age of HLA region SNPs in relation to classic HLA gene alleles within Europe. European Journal of Human Genetics : Ejhg. 18: 924-32. PMID 20354563 DOI: 10.1038/ejhg.2010.32  0.44
2010 Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Fernández-Viña M, Geraghty DE, Holdsworth R, Hurley CK, Lau M, Lee KW, Mach B, Maiers M, Mayr WR, et al. An update to HLA nomenclature, 2010. Bone Marrow Transplantation. 45: 846-8. PMID 20348972 DOI: 10.1038/Bmt.2010.79  0.44
2010 Bodmer WF. Commentary: Connections between genetics and statistics: a commentary on Fisher's 1951 Bateson lecture--'Statistical Methods in Genetics'. International Journal of Epidemiology. 39: 340-4. PMID 20176586 DOI: 10.1093/ije/dyq014  0.44
2010 Yeung TM, Gandhi SC, Wilding JL, Muschel R, Bodmer WF. Cancer stem cells from colorectal cancer-derived cell lines. Proceedings of the National Academy of Sciences of the United States of America. 107: 3722-7. PMID 20133591 DOI: 10.1073/Pnas.0915135107  0.44
2010 Bodmer W. Public understanding of science: The BA, The Royal Society and COPUS Notes and Records of the Royal Society. 64: S151-S161. DOI: 10.1098/Rsnr.2010.0035  0.44
2009 Ashraf SQ, Umana P, Mössner E, Ntouroupi T, Brünker P, Schmidt C, Wilding JL, Mortensen NJ, Bodmer WF. Humanised IgG1 antibody variants targeting membrane-bound carcinoembryonic antigen by antibody-dependent cellular cytotoxicity and phagocytosis. British Journal of Cancer. 101: 1758-68. PMID 19904275 DOI: 10.1038/sj.bjc.6605355  0.44
2009 Bodmer W. Sam Karlin: a personal appreciation. Theoretical Population Biology. 75: 230-2. PMID 19496242 DOI: 10.1016/J.Tpb.2009.01.005  0.44
2009 Chan CW, Wong NA, Liu Y, Bicknell D, Turley H, Hollins L, Miller CJ, Wilding JL, Bodmer WF. Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1. Proceedings of the National Academy of Sciences of the United States of America. 106: 1936-41. PMID 19188603 DOI: 10.1073/pnas.0812904106  0.44
2009 Yardy GW, Bicknell DC, Wilding JL, Bartlett S, Liu Y, Winney B, Turner GD, Brewster SF, Bodmer WF. Mutations in the AXIN1 gene in advanced prostate cancer. European Urology. 56: 486-94. PMID 18514389 DOI: 10.1016/j.eururo.2008.05.029  0.44
2008 Ntouroupi TG, Ashraf SQ, McGregor SB, Turney BW, Seppo A, Kim Y, Wang X, Kilpatrick MW, Tsipouras P, Tafas T, Bodmer WF. Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope. British Journal of Cancer. 99: 789-95. PMID 18682708 DOI: 10.1038/sj.bjc.6604545  0.44
2008 Bodmer W, Bonilla C. Common and rare variants in multifactorial susceptibility to common diseases. Nature Genetics. 40: 695-701. PMID 18509313 DOI: 10.1038/Ng.F.136  0.44
2008 Bodmer W, Bielas JH, Beckman RA. Genetic instability is not a requirement for tumor development. Cancer Research. 68: 3558-60; discussion . PMID 18483234 DOI: 10.1158/0008-5472.Can-07-6544  0.44
2008 Conaghan P, Ashraf S, Tytherleigh M, Wilding J, Tchilian E, Bicknell D, Mortensen NJ, Bodmer W. Targeted killing of colorectal cancer cell lines by a humanised IgG1 monoclonal antibody that binds to membrane-bound carcinoembryonic antigen. British Journal of Cancer. 98: 1217-25. PMID 18349843 DOI: 10.1038/Sj.Bjc.6604289  0.44
2008 Hennig BJ, Fry AE, Hirai K, Tahara H, Tamori A, Moller M, Hopkin J, Hill AV, Bodmer W, Beverley P, Tchilian E. PTPRC (CD45) variation and disease association studied using single nucleotide polymorphism tagging. Tissue Antigens. 71: 458-63. PMID 18312479 DOI: 10.1111/J.1399-0039.2008.01014.X  0.44
2008 Emaduddin M, Bicknell DC, Bodmer WF, Feller SM. Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 2358-62. PMID 18258742 DOI: 10.1073/pnas.0712176105  0.44
2008 Ashraf SQ, Conaghan PJ, Wilding JL, Bodmer WF. Reply: In vitro and in vivo anticancer efficacy of unconjugated humanised anti-CEA monoclonal antibodies British Journal of Cancer. 99: 839-840. DOI: 10.1038/sj.bjc.6604549  0.44
2008 Bodmer W. Molecular and Genetic Organization: The Future Human Genetics: Possibilities and Realities. 395-411. DOI: 10.1002/9780470720486.ch17  0.44
2007 Johnston MD, Edwards CM, Bodmer WF, Maini PK, Chapman SJ. Examples of mathematical modeling: tales from the crypt. Cell Cycle (Georgetown, Tex.). 6: 2106-12. PMID 17873520  0.44
2007 Dahl F, Stenberg J, Fredriksson S, Welch K, Zhang M, Nilsson M, Bicknell D, Bodmer WF, Davis RW, Ji H. Multigene amplification and massively parallel sequencing for cancer mutation discovery. Proceedings of the National Academy of Sciences of the United States of America. 104: 9387-92. PMID 17517648 DOI: 10.1073/Pnas.0702165104  0.44
2007 Cotton RG, Appelbe W, Auerbach AD, Becker K, Bodmer W, Boone DJ, Boulyjenkov V, Brahmachari S, Brody L, Brookes A, Brown AF, Byers P, Cantu JM, Cassiman JJ, et al. Recommendations of the 2006 Human Variome Project meeting. Nature Genetics. 39: 433-6. PMID 17392799 DOI: 10.1038/Ng2024  0.44
2007 Johnston MD, Edwards CM, Bodmer WF, Maini PK, Chapman SJ. Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America. 104: 4008-13. PMID 17360468 DOI: 10.1073/pnas.0611179104  0.44
2007 Bredberg A, Bodmer W. Cytostatic drug treatment causes seeding of gene promoter methylation. European Journal of Cancer (Oxford, England : 1990). 43: 947-54. PMID 17236756 DOI: 10.1016/J.Ejca.2006.12.003  0.44
2007 Van Leeuwen IMM, Byrne HM, Johnston MD, Edwards CM, Chapman SJ, Bodmer WF, Maini PK. Modelling multiscale aspects of colorectal cancer Aip Conference Proceedings. 971: 3-7. DOI: 10.1063/1.2883865  0.44
2006 Felix R, Bodmer W, Fearnhead NS, van der Merwe L, Goldberg P, Ramesar RS. GSTM1 and GSTT1 polymorphisms as modifiers of age at diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC) in a homogeneous cohort of individuals carrying a single predisposing mutation. Mutation Research. 602: 175-81. PMID 17087981 DOI: 10.1016/J.Mrfmmm.2006.09.004  0.44
2006 Bodmer WF. Cancer genetics: colorectal cancer as a model. Journal of Human Genetics. 51: 391-6. PMID 16596323 DOI: 10.1007/s10038-006-0373-x  0.44
2006 Ward V, Hennig BJ, Hirai K, Tahara H, Tamori A, Dawes R, Saito M, Bangham C, Stephens H, Goldfeld AE, Kunachiwa W, Leetrakool N, Hopkin J, Dunstan S, Hill A, ... Bodmer W, et al. Geographical distribution and disease associations of the CD45 exon 6 138G variant. Immunogenetics. 58: 235-9. PMID 16538473 DOI: 10.1007/S00251-006-0099-0  0.44
2006 Dawes R, Hennig B, Irving W, Petrova S, Boxall S, Ward V, Wallace D, Macallan DC, Thursz M, Hill A, Bodmer W, Beverley PC, Tchilian EZ. Altered CD45 expression in C77G carriers influences immune function and outcome of hepatitis C infection. Journal of Medical Genetics. 43: 678-84. PMID 16505159 DOI: 10.1136/Jmg.2005.040485  0.44
2006 Wong NA, Warren BF, Piris J, Maynard N, Marshall R, Bodmer WF. EpCAM and gpA33 are markers of Barrett's metaplasia. Journal of Clinical Pathology. 59: 260-3. PMID 16473928 DOI: 10.1136/Jcp.2005.027474  0.44
2006 Liu Y, Bodmer WF. Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines. Proceedings of the National Academy of Sciences of the United States of America. 103: 976-81. PMID 16418264 DOI: 10.1073/pnas.0510146103  0.44
2006 Bodmer WF. Cancer and evolution Israel Journal of Ecology and Evolution. 52: 233-245.  0.44
2005 Bicknell DC, Bodmer WF. A mutated HLA-A*0101 allele in the colorectal cell line HCA-7. Tissue Antigens. 66: 231-7. PMID 16101834 DOI: 10.1111/j.1399-0039.2005.00456.x  0.44
2005 Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Geraghty DE, Hansen JA, Hurley CK, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, et al. Nomenclature for Factors of the HLA System, 2004. Human Immunology. 66: 571-636. PMID 15935895 DOI: 10.1016/j.humimm.2005.02.002  0.44
2005 Wong NA, Wilding J, Bartlett S, Liu Y, Warren BF, Piris J, Maynard N, Marshall R, Bodmer WF. CDX1 is an important molecular mediator of Barrett's metaplasia. Proceedings of the National Academy of Sciences of the United States of America. 102: 7565-70. PMID 15894614 DOI: 10.1073/pnas.0502031102  0.44
2005 Zbar AP, Thomas H, Wilkinson RW, Wadhwa M, Syrigos KN, Ross EL, Dilger P, Allen-Mersh TG, Kmiot WA, Epenetos AA, Snary D, Bodmer WF. Immune responses in advanced colorectal cancer following repeated intradermal vaccination with the anti-CEA murine monoclonal antibody, PR1A3: results of a phase I study. International Journal of Colorectal Disease. 20: 403-14. PMID 15864608 DOI: 10.1007/s00384-004-0726-x  0.44
2005 Kim JC, Roh SA, Koo KH, Cho YK, Kim HC, Yu CS, Oh SJ, Ryu JS, Bicknell DC, Bodmer WF. Preclinical application of radioimmunoguided surgery using anti-carcinoembryonic antigen biparatopic antibody in the colon cancer. European Surgical Research. Europã¤Ische Chirurgische Forschung. Recherches Chirurgicales Europã©Ennes. 37: 36-44. PMID 15818040 DOI: 10.1159/000083146  0.44
2005 Yardy G, McGregor S, Bodmer W. The molecular staging of prostate cancer. Bju International. 95: 907. PMID 15794810 DOI: 10.1111/J.1464-410X.2004.05145.X  0.44
2005 Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Geraghty DE, Hansen JA, Hurley CK, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, et al. Nomenclature for factors of the HLA system, 2004. Tissue Antigens. 65: 301-69. PMID 15787720 DOI: 10.1111/j.1399-0039.2005.00379.x  0.44
2005 Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Geraghty DE, Hansen JA, Hurley CK, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, et al. Nomenclature for factors of the HLA system, 2004. International Journal of Immunogenetics. 32: 107-59. PMID 15787643 DOI: 10.1111/J.1744-313X.2005.00509.X  0.44
2005 Fearnhead NS, Winney B, Bodmer WF. Rare variant hypothesis for multifactorial inheritance: susceptibility to colorectal adenomas as a model. Cell Cycle (Georgetown, Tex.). 4: 521-5. PMID 15753653  0.44
2005 Haines J, Johnson V, Pack K, Suraweera N, Slijepcevic P, Cabuy E, Coster M, Ilyas M, Wilding J, Sieber O, Bodmer W, Tomlinson I, Silver A. Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 2868-73. PMID 15710876 DOI: 10.1073/Pnas.0500039102  0.44
2004 Bodmer W. Prostate Cancer Charitable Trust 2004 Forum: a personal overview. Prostate Cancer and Prostatic Diseases. 7: 277-81. PMID 15545979 DOI: 10.1038/Sj.Pcan.4500766  0.44
2004 Fearnhead NS, Wilding JL, Winney B, Tonks S, Bartlett S, Bicknell DC, Tomlinson IP, Mortensen NJ, Bodmer WF. Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas. Proceedings of the National Academy of Sciences of the United States of America. 101: 15992-7. PMID 15520370 DOI: 10.1073/pnas.0407187101  0.44
2004 Kim JC, Roh SA, Koo KH, Ka IH, Kim HC, Yu CS, Lee KH, Kim JS, Lee HI, Bodmer WF. Genotyping possible polymorphic variants of human mismatch repair genes in healthy Korean individuals and sporadic colorectal cancer patients. Familial Cancer. 3: 129-37. PMID 15340264 DOI: 10.1023/B:FAME.0000039919.66461.8f  0.44
2004 Boxall S, Stanton T, Hirai K, Ward V, Yasui T, Tahara H, Tamori A, Nishiguchi S, Shiomi S, Ishiko O, Inaba M, Nishizawa Y, Dawes R, Bodmer W, Beverley PC, et al. Disease associations and altered immune function in CD45 138G variant carriers. Human Molecular Genetics. 13: 2377-84. PMID 15333587 DOI: 10.1093/Hmg/Ddh276  0.44
2004 Douglas EJ, Fiegler H, Rowan A, Halford S, Bicknell DC, Bodmer W, Tomlinson IP, Carter NP. Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas. Cancer Research. 64: 4817-25. PMID 15256451 DOI: 10.1158/0008-5472.Can-04-0328  0.44
2004 Stanton T, Boxall S, Bennett A, Kaleebu P, Watera C, Whitworth J, French N, Dawes R, Hill AV, Bodmer W, Beverley PC, Tchilian EZ. CD45 variant alleles: possibly increased frequency of a novel exon 4 CD45 polymorphism in HIV seropositive Ugandans. Immunogenetics. 56: 107-10. PMID 15057492 DOI: 10.1007/S00251-004-0668-Z  0.44
2004 Wong NA, Britton MP, Choi GS, Stanton TK, Bicknell DC, Wilding JL, Bodmer WF. Loss of CDX1 expression in colorectal carcinoma: promoter methylation, mutation, and loss of heterozygosity analyses of 37 cell lines. Proceedings of the National Academy of Sciences of the United States of America. 101: 574-9. PMID 14704280 DOI: 10.1073/pnas.0307190101  0.44
2003 Bodmer W. RA Fisher, statistician and geneticist extraordinary: a personal view. International Journal of Epidemiology. 32: 938-42; discussion 9. PMID 14681250 DOI: 10.1093/Ije/Dyg289  0.44
2003 Halford SE, Sawyer EJ, Lambros MB, Gorman P, Macdonald ND, Talbot IC, Foulkes WD, Gillett CE, Barnes DM, Akslen LA, Lee K, Jacobs IJ, Hanby AM, Ganesan TS, Salvesen HB, ... Bodmer WF, et al. MSI-low, a real phenomenon which varies in frequency among cancer types. The Journal of Pathology. 201: 389-94. PMID 14595750 DOI: 10.1002/path.1453  0.44
2003 Pagel M, Bodmer W. A naked ape would have fewer parasites. Proceedings. Biological Sciences / the Royal Society. 270: S117-9. PMID 12952654 DOI: 10.1098/Rsbl.2003.0041  0.44
2003 Preston SL, Wong WM, Chan AO, Poulsom R, Jeffery R, Goodlad RA, Mandir N, Elia G, Novelli M, Bodmer WF, Tomlinson IP, Wright NA. Bottom-up histogenesis of colorectal adenomas: origin in the monocryptal adenoma and initial expansion by crypt fission. Cancer Research. 63: 3819-25. PMID 12839979  0.44
2003 Stanton T, Boxall S, Hirai K, Dawes R, Tonks S, Yasui T, Kanaoka Y, Yuldasheva N, Ishiko O, Bodmer W, Beverley PC, Tchilian EZ. A high-frequency polymorphism in exon 6 of the CD45 tyrosine phosphatase gene (PTPRC) resulting in altered isoform expression. Proceedings of the National Academy of Sciences of the United States of America. 100: 5997-6002. PMID 12716971 DOI: 10.1073/Pnas.0931490100  0.44
2003 Halford SE, Rowan AJ, Lipton L, Sieber OM, Pack K, Thomas HJ, Hodgson SV, Bodmer WF, Tomlinson IP. Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers. The American Journal of Pathology. 162: 1545-8. PMID 12707038 DOI: 10.1016/S0002-9440(10)64288-5  0.44
2003 Jaeger EE, Woodford-Richens KL, Lockett M, Rowan AJ, Sawyer EJ, Heinimann K, Rozen P, Murday VA, Whitelaw SC, Ginsberg A, Atkin WS, Lynch HT, Southey MC, Debinski H, Eng C, ... Bodmer WF, et al. An ancestral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome. American Journal of Human Genetics. 72: 1261-7. PMID 12696020 DOI: 10.1086/375144  0.44
2003 Novelli M, Cossu A, Oukrif D, Quaglia A, Lakhani S, Poulsom R, Sasieni P, Carta P, Contini M, Pasca A, Palmieri G, Bodmer W, Tanda F, Wright N. X-inactivation patch size in human female tissue confounds the assessment of tumor clonality. Proceedings of the National Academy of Sciences of the United States of America. 100: 3311-4. PMID 12610207 DOI: 10.1073/Pnas.0437825100  0.44
2002 Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Geraghty DE, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf E, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA system, 2002. Tissue Antigens. 60: 407-64. PMID 12492818 DOI: 10.1034/J.1399-0039.2002.600509.X  0.44
2002 Sieber OM, Heinimann K, Gorman P, Lamlum H, Crabtree M, Simpson CA, Davies D, Neale K, Hodgson SV, Roylance RR, Phillips RK, Bodmer WF, Tomlinson IP. Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC. Proceedings of the National Academy of Sciences of the United States of America. 99: 16910-5. PMID 12486240 DOI: 10.1073/pnas.012679099  0.44
2002 Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Geraghty DE, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA system, 2002. Human Immunology. 63: 1213-68. PMID 12480266 DOI: 10.1016/S0198-8859(02)00769-3  0.44
2002 Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Geraghty DE, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA system, 2002. European Journal of Immunogenetics : Official Journal of the British Society For Histocompatibility and Immunogenetics. 29: 463-515. PMID 12437610 DOI: 10.1046/j.1365-2370.2002.00359.x  0.44
2002 Fearnhead NS, Wilding JL, Bodmer WF. Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis. British Medical Bulletin. 64: 27-43. PMID 12421723 DOI: 10.1093/bmb/64.1.27  0.44
2002 Wilding J, Straub J, Bee J, Churchman M, Bodmer W, Dickson C, Tomlinson I, Ilyas M. Cyclin D1 is not an essential target of beta-catenin signaling during intestinal tumorigenesis, but it may act as a modifier of disease severity in multiple intestinal neoplasia (Min) mice. Cancer Research. 62: 4562-5. PMID 12183406  0.44
2002 Cann HM, de Toma C, Cazes L, Legrand MF, Morel V, Piouffre L, Bodmer J, Bodmer WF, Bonne-Tamir B, Cambon-Thomsen A, Chen Z, Chu J, Carcassi C, Contu L, Du R, et al. A human genome diversity cell line panel. Science (New York, N.Y.). 296: 261-2. PMID 11954565 DOI: 10.1126/Science.296.5566.261B  0.44
2002 Tomlinson I, Sasieni P, Bodmer W. How many mutations in a cancer? The American Journal of Pathology. 160: 755-8. PMID 11891172 DOI: 10.1016/S0002-9440(10)64896-1  0.44
2002 Sieber OM, Lamlum H, Crabtree MD, Rowan AJ, Barclay E, Lipton L, Hodgson S, Thomas HJ, Neale K, Phillips RK, Farrington SM, Dunlop MG, Mueller HJ, Bisgaard ML, Bulow S, ... ... Bodmer W, et al. Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas. Proceedings of the National Academy of Sciences of the United States of America. 99: 2954-8. PMID 11867715 DOI: 10.1073/Pnas.042699199  0.44
2002 Kim JC, Roh SA, Koo KH, Ryu JH, Hong HK, Oh SJ, Ryu JS, Kim HJ, Bodmer WF. Enhancement of colorectal tumor targeting using a novel biparatopic monoclonal antibody against carcinoembryonic antigen in experimental radioimmunoguided surgery. International Journal of Cancer. Journal International Du Cancer. 97: 542-7. PMID 11802220 DOI: 10.1002/ijc.1630  0.44
2002 Wheeler JM, Warren BF, Mortensen NJ, Kim HC, Biddolph SC, Elia G, Beck NE, Williams GT, Shepherd NA, Bateman AC, Bodmer WF. An insight into the genetic pathway of adenocarcinoma of the small intestine. Gut. 50: 218-23. PMID 11788563 DOI: 10.1136/gut.50.2.218  0.44
2002 Halford S, Sasieni P, Rowan A, Wasan H, Bodmer W, Talbot I, Hawkins N, Ward R, Tomlinson I. Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait. Cancer Research. 62: 53-7. PMID 11782358  0.44
2001 Kim JC, Kim HC, Roh SA, Koo KH, Lee DH, Yu CS, Lee JH, Kim TW, Lee HL, Beck NE, Bodmer WF. hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. Cancer Detection and Prevention. 25: 503-10. PMID 12132870  0.44
2001 Zhou XP, Woodford-Richens K, Lehtonen R, Kurose K, Aldred M, Hampel H, Launonen V, Virta S, Pilarski R, Salovaara R, Bodmer WF, Conrad BA, Dunlop M, Hodgson SV, Iwama T, et al. Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes. American Journal of Human Genetics. 69: 704-11. PMID 11536076 DOI: 10.1086/323703  0.44
2001 Wells RS, Yuldasheva N, Ruzibakiev R, Underhill PA, Evseeva I, Blue-Smith J, Jin L, Su B, Pitchappan R, Shanmugalakshmi S, Balakrishnan K, Read M, Pearson NM, Zerjal T, Webster MT, ... ... Bodmer WF, et al. The Eurasian heartland: a continental perspective on Y-chromosome diversity. Proceedings of the National Academy of Sciences of the United States of America. 98: 10244-9. PMID 11526236 DOI: 10.1073/pnas.171305098  0.44
2001 Wilkinson RW, Ross EL, Poulsom R, Ilyas M, Straub J, Snary D, Bodmer WF, Mather SJ. Antibody targeting studies in a transgenic murine model of spontaneous colorectal tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 10256-60. PMID 11517330 DOI: 10.1073/pnas.181353498  0.44
2001 Woodford-Richens KL, Rowan AJ, Gorman P, Halford S, Bicknell DC, Wasan HS, Roylance RR, Bodmer WF, Tomlinson IP. SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway. Proceedings of the National Academy of Sciences of the United States of America. 98: 9719-23. PMID 11481457 DOI: 10.1073/pnas.171321498  0.44
2001 Marsh SG, Bodmer JG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, MacH B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA system, 2000. European Journal of Immunogenetics : Official Journal of the British Society For Histocompatibility and Immunogenetics. 28: 377-424. PMID 11422419 DOI: 10.1046/j.1365-2370.2001.00268.x  0.44
2001 Woodford-Richens KL, Halford S, Rowan A, Bevan S, Aaltonen LA, Wasan H, Bicknell D, Bodmer WF, Houlston RS, Tomlinson IP. CDX2 mutations do not account for juvenile polyposis or Peutz-Jeghers syndrome and occur infrequently in sporadic colorectal cancers. British Journal of Cancer. 84: 1314-6. PMID 11355940 DOI: 10.1054/bjoc.2001.1800  0.44
2001 Marsh SG, Bodmer JG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA system, 2000. Human Immunology. 62: 419-68. PMID 11295476 DOI: 10.1016/S0198-8859(01)00229-4  0.44
2001 Marsh SG, Bodmer JG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA system, 2000. Tissue Antigens. 57: 236-83. PMID 11285132 DOI: 10.1034/j.1399-0039.2001.057003236.x  0.44
2001 Fearnhead NS, Britton MP, Bodmer WF. The ABC of APC. Human Molecular Genetics. 10: 721-33. PMID 11257105  0.44
2001 Bartlett S, Straub J, Tonks S, Wells RS, Bodmer JG, Bodmer WF. Alkaline-mediated differential interaction (AMDI): a simple automatable single-nucleotide polymorphism assay. Proceedings of the National Academy of Sciences of the United States of America. 98: 2694-7. PMID 11226301 DOI: 10.1073/pnas.041619998  0.44
2001 Abdel-Rahman WM, Katsura K, Rens W, Gorman PA, Sheer D, Bicknell D, Bodmer WF, Arends MJ, Wyllie AH, Edwards PA. Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement. Proceedings of the National Academy of Sciences of the United States of America. 98: 2538-43. PMID 11226274 DOI: 10.1073/pnas.041603298  0.44
2001 Wheeler JM, Kim HC, Efstathiou JA, Ilyas M, Mortensen NJ, Bodmer WF. Hypermethylation of the promoter region of the E-cadherin gene (CDH1) in sporadic and ulcerative colitis associated colorectal cancer. Gut. 48: 367-71. PMID 11171827 DOI: 10.1136/gut.48.3.367  0.44
2001 Tonks S, Bartlett SM, Curtis LJ, Bodmer JG, Bodmer WF. Simple and effective SNP detection without gels European Journal of Immunogenetics. 28: 201.  0.44
2001 Bicknell DC, Bodmer WF. "Null" HLA A*0101 mutation identified in a colorectal cancer cell line European Journal of Immunogenetics. 28: 308.  0.44
2000 Bodmer WF. Prostate cancer 2000. Prostate Cancer and Prostatic Diseases. 3: 218-223. PMID 12497067 DOI: 10.1038/Sj.Pcan.4500485  0.44
2000 Playford MP, Bicknell D, Bodmer WF, Macaulay VM. Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin. Proceedings of the National Academy of Sciences of the United States of America. 97: 12103-8. PMID 11035789 DOI: 10.1073/pnas.210394297  0.44
2000 Lamlum H, Al Tassan N, Jaeger E, Frayling I, Sieber O, Reza FB, Eckert M, Rowan A, Barclay E, Atkin W, Williams C, Gilbert J, Cheadle J, Bell J, Houlston R, ... Bodmer W, et al. Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q. Human Molecular Genetics. 9: 2215-21. PMID 11001924 DOI: 10.1093/Oxfordjournals.Hmg.A018912  0.44
2000 Kim JC, Kim WS, Ryu JS, Oh SJ, Lee DH, Koo KH, Roh SA, Kim HC, Yu CS, Kang GH, Bodmer WF. Applicability of carcinoembryonic antigen-specific monoclonal antibodies to radioimmunoguided surgery for human colorectal carcinoma. Cancer Research. 60: 4825-9. PMID 10987293  0.44
2000 Wheeler JM, Loukola A, Aaltonen LA, Mortensen NJ, Bodmer WF. The role of hypermethylation of the hMLH1 promoter region in HNPCC versus MSI+ sporadic colorectal cancers. Journal of Medical Genetics. 37: 588-92. PMID 10922385  0.44
2000 Kim HC, Wheeler JM, Kim JC, Ilyas M, Beck NE, Kim BS, Park KC, Bodmer WF. The E-cadherin gene (CDH1) variants T340A and L599V in gastric and colorectal cancer patients in Korea. Gut. 47: 262-7. PMID 10896919 DOI: 10.1136/gut.47.2.262  0.44
2000 Wheeler JM, Bodmer WF, Mortensen NJ. DNA mismatch repair genes and colorectal cancer. Gut. 47: 148-53. PMID 10861278 DOI: 10.1136/gut.47.1.148  0.44
2000 Woodford-Richens K, Bevan S, Churchman M, Dowling B, Jones D, Norbury CG, Hodgson SV, Desai D, Neale K, Phillips RK, Young J, Leggett B, Dunlop M, Rozen P, Eng C, ... ... Bodmer WF, et al. Analysis of genetic and phenotypic heterogeneity in juvenile polyposis. Gut. 46: 656-60. PMID 10764709 DOI: 10.1136/Gut.46.5.656  0.44
2000 Rowan AJ, Lamlum H, Ilyas M, Wheeler J, Straub J, Papadopoulou A, Bicknell D, Bodmer WF, Tomlinson IP. APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits". Proceedings of the National Academy of Sciences of the United States of America. 97: 3352-7. PMID 10737795 DOI: 10.1073/pnas.97.7.3352  0.44
2000 Lamlum H, Papadopoulou A, Ilyas M, Rowan A, Gillet C, Hanby A, Talbot I, Bodmer W, Tomlinson I. APC mutations are sufficient for the growth of early colorectal adenomas. Proceedings of the National Academy of Sciences of the United States of America. 97: 2225-8. PMID 10681434 DOI: 10.1073/Pnas.040564697  0.44
1999 Ilyas M, Straub J, Tomlinson IP, Bodmer WF. Genetic pathways in colorectal and other cancers. European Journal of Cancer (Oxford, England : 1990). 35: 1986-2002. PMID 10711241 DOI: 10.1016/S0959-8049(99)00298-1  0.44
1999 Gelsthorpe AR, Wells RS, Lowe AP, Tonks S, Bodmer JG, Bodmer WF. High-throughput class I HLA genotyping using fluorescence resonance energy transfer (FRET) probes and sequence-specific primer-polymerase chain reaction (SSP-PCR). Tissue Antigens. 54: 603-14. PMID 10674976 DOI: 10.1034/j.1399-0039.1999.540611.x  0.44
1999 Swale VJ, Quinn AG, Wheeler JM, Beck NE, Dove-Edwin I, Thomas HJ, Bodmer WF, Bataille VA. Microsatellite instability in benign skin lesions in hereditary non-polyposis colorectal cancer syndrome. The Journal of Investigative Dermatology. 113: 901-5. PMID 10594728 DOI: 10.1046/j.1523-1747.1999.00788.x  0.44
1999 Bodmer WF. 1998 Runme Shaw Memorial Lecture: somatic evolution of cancer. Annals of the Academy of Medicine, Singapore. 28: 323-9. PMID 10575514  0.44
1999 Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA system, 1998. Vox Sanguinis. 77: 164-91. PMID 10545854 DOI: 10.1046/J.1423-0410.1999.7730164.X  0.44
1999 Bodmer W. Familial adenomatous polyposis (FAP) and its gene, APC. Cytogenetics and Cell Genetics. 86: 99-104. PMID 10545698 DOI: 10.1159/000015360  0.44
1999 Novelli MR, Wasan H, Rosewell I, Bee J, Tomlinson IP, Wright NA, Bodmer WF. Tumor burden and clonality in multiple intestinal neoplasia mouse/normal mouse aggregation chimeras. Proceedings of the National Academy of Sciences of the United States of America. 96: 12553-8. PMID 10535960 DOI: 10.1073/pnas.96.22.12553  0.44
1999 Kim JC, Roh SA, Kim HC, Yu CS, Lee DH, Ahn BY, Kim KM, Yang SK, Kang GH, Beck NE, Bodmer WF. Somatic mutations of the first 14 exons of APC in hamartomatous polyps of the colon. Human Mutation. 14: 351-2. PMID 10502830 DOI: 10.1002/(SICI)1098-1004(199910)14:4<351::AID-HUMU13>3.0.CO;2-M  0.44
1999 Lamlum H, Ilyas M, Rowan A, Clark S, Johnson V, Bell J, Frayling I, Efstathiou J, Pack K, Payne S, Roylance R, Gorman P, Sheer D, Neale K, Phillips R, ... ... Bodmer W, et al. The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis. Nature Medicine. 5: 1071-5. PMID 10470088 DOI: 10.1038/12511  0.44
1999 Wheeler JM, Beck NE, Kim HC, Tomlinson IP, Mortensen NJ, Bodmer WF. Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: the predominant role of hMLH1. Proceedings of the National Academy of Sciences of the United States of America. 96: 10296-301. PMID 10468602 DOI: 10.1073/pnas.96.18.10296  0.44
1999 Bodmer J, Bodmer W. Rose Payne 1909-1999. With personal recollections by Julia and Walter Bodmer. Tissue Antigens. 54: 102-5. PMID 10458330 DOI: 10.1034/J.1399-0039.1999.540113.X  0.44
1999 Ilyas M, Straub J, Tomlinson IP, Bodmer WF. Genetic pathways in colorectal and other cancers. European Journal of Cancer (Oxford, England : 1990). 35: 335-51. PMID 10448282 DOI: 10.1016/S0959-8049(98)00431-6  0.44
1999 Kim JC, Koo KH, Kim BS, Park KC, Bicknell DC, Bodmer WF. Carcino-embryonic antigen may function as a chemo-attractant in colorectal-carcinoma cell lines. International Journal of Cancer. Journal International Du Cancer. 82: 880-5. PMID 10446457 DOI: 10.1002/(SICI)1097-0215(19990909)82:6<880::AID-IJC18>3.0.CO;2-S  0.44
1999 Bevan S, Woodford-Richens K, Rozen P, Eng C, Young J, Dunlop M, Neale K, Phillips R, Markie D, Rodriguez-Bigas M, Leggett B, Sheridan E, Hodgson S, Iwama T, Eccles D, ... Bodmer W, et al. Screening SMAD1, SMAD2, SMAD3, and SMAD5 for germline mutations in juvenile polyposis syndrome. Gut. 45: 406-8. PMID 10446110 DOI: 10.1136/Gut.45.3.406  0.44
1999 Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA System, 1998. Human Immunology. 60: 361-95. PMID 10363728 DOI: 10.1016/S0198-8859(99)00042-7  0.44
1999 Kim JC, Han MS, Lee HK, Kim WS, Park SK, Park KC, Bodmer WF, Rowan AJ, Kim OJ. Distribution of carcinoembryonic antigen and biologic behavior in colorectal carcinoma. Diseases of the Colon and Rectum. 42: 640-8. PMID 10344687 DOI: 10.1007/BF02234143  0.44
1999 Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA system, 1998. European Journal of Immunogenetics : Official Journal of the British Society For Histocompatibility and Immunogenetics. 26: 81-116. PMID 10331156 DOI: 10.1046/J.1365-2370.1999.00164.X  0.44
1999 Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA system, 1998. Tissue Antigens. 53: 407-46. PMID 10321590 DOI: 10.1034/J.1399-0039.1999.530421.X  0.44
1999 Rowan A, Bataille V, MacKie R, Healy E, Bicknell D, Bodmer W, Tomlinson I. Somatic mutations in the Peutz-Jeghers (LKB1/STKII) gene in sporadic malignant melanomas. The Journal of Investigative Dermatology. 112: 509-11. PMID 10201537 DOI: 10.1046/J.1523-1747.1999.00551.X  0.44
1999 Ilyas M, Efstathiou JA, Straub J, Kim HC, Bodmer WF. Transforming growth factor beta stimulation of colorectal cancer cell lines: type II receptor bypass and changes in adhesion molecule expression. Proceedings of the National Academy of Sciences of the United States of America. 96: 3087-91. PMID 10077641 DOI: 10.1073/pnas.96.6.3087  0.44
1999 Efstathiou JA, Liu D, Wheeler JM, Kim HC, Beck NE, Ilyas M, Karayiannakis AJ, Mortensen NJ, Kmiot W, Playford RJ, Pignatelli M, Bodmer WF. Mutated epithelial cadherin is associated with increased tumorigenicity and loss of adhesion and of responsiveness to the motogenic trefoil factor 2 in colon carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 2316-21. PMID 10051639 DOI: 10.1073/pnas.96.5.2316  0.44
1999 Mann B, Gelos M, Siedow A, Hanski ML, Gratchev A, Ilyas M, Bodmer WF, Moyer MP, Riecken EO, Buhr HJ, Hanski C. Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas. Proceedings of the National Academy of Sciences of the United States of America. 96: 1603-8. PMID 9990071 DOI: 10.1073/pnas.96.4.1603  0.44
1999 Tomlinson I, Bodmer W. Selection, the mutation rate and cancer: ensuring that the tail does not wag the dog. Nature Medicine. 5: 11-2. PMID 9883827 DOI: 10.1038/4687  0.44
1998 Ilyas M, Hao XP, Wilkinson K, Tomlinson IP, Abbasi AM, Forbes A, Bodmer WF, Talbot IC. Loss of Bcl-2 expression correlates with tumour recurrence in colorectal cancer. Gut. 43: 383-7. PMID 9863484  0.44
1998 Houlston R, Bevan S, Williams A, Young J, Dunlop M, Rozen P, Eng C, Markie D, Woodford-Richens K, Rodriguez-Bigas MA, Leggett B, Neale K, Phillips R, Sheridan E, Hodgson S, ... ... Bodmer W, et al. Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases. Human Molecular Genetics. 7: 1907-12. PMID 9811934 DOI: 10.1093/Hmg/7.12.1907  0.44
1998 Wasan HS, Park HS, Liu KC, Mandir NK, Winnett A, Sasieni P, Bodmer WF, Goodlad RA, Wright NA. APC in the regulation of intestinal crypt fission. The Journal of Pathology. 185: 246-55. PMID 9771477 DOI: 10.1002/(SICI)1096-9896(199807)185:3<246::AID-PATH90>3.0.CO;2-8  0.44
1998 Frayling IM, Beck NE, Ilyas M, Dove-Edwin I, Goodman P, Pack K, Bell JA, Williams CB, Hodgson SV, Thomas HJ, Talbot IC, Bodmer WF, Tomlinson IP. The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history. Proceedings of the National Academy of Sciences of the United States of America. 95: 10722-7. PMID 9724771 DOI: 10.1073/pnas.95.18.10722  0.44
1998 Tomlinson I, Ilyas M, Johnson V, Davies A, Clark G, Talbot I, Bodmer W. A comparison of the genetic pathways involved in the pathogenesis of three types of colorectal cancer. The Journal of Pathology. 184: 148-52. PMID 9602705 DOI: 10.1002/(Sici)1096-9896(199802)184:2<148::Aid-Path986>3.0.Co;2-M  0.44
1998 Efstathiou JA, Noda M, Rowan A, Dixon C, Chinery R, Jawhari A, Hattori T, Wright NA, Bodmer WF, Pignatelli M. Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 3122-7. PMID 9501226 DOI: 10.1073/pnas.95.6.3122  0.44
1998 Homfray TF, Cottrell SE, Ilyas M, Rowan A, Talbot IC, Bodmer WF, Tomlinson IP. Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours. Human Mutation. 11: 114-20. PMID 9482574 DOI: 10.1002/(SICI)1098-1004(1998)11:2<114::AID-HUMU3>3.0.CO;2-J  0.44
1998 Olschwang S, Markie D, Seal S, Neale K, Phillips R, Cottrell S, Ellis I, Hodgson S, Zauber P, Spigelman A, Iwama T, Loff S, McKeown C, Marchese C, Sampson J, ... ... Bodmer W, et al. Peutz-Jeghers disease: most, but not all, families are compatible with linkage to 19p13.3. Journal of Medical Genetics. 35: 42-4. PMID 9475093 DOI: 10.1136/Jmg.35.1.42  0.44
1998 Hemminki A, Markie D, Tomlinson I, Avizienyte E, Roth S, Loukola A, Bignell G, Warren W, Aminoff M, Höglund P, Järvinen H, Kristo P, Pelin K, Ridanpää M, Salovaara R, ... ... Bodmer W, et al. A serine/threonine kinase gene defective in Peutz-Jeghers syndrome. Nature. 391: 184-7. PMID 9428765 DOI: 10.1038/34432  0.44
1998 Bodmer JG, Marsh SGE, Albert ED, Bodmer WF, Bontrop RE, Charron D, Dupont B, Erlich HA, Fauchet R, Mach B, Mayr WR, Parham P, Sasazuki T, Schreuder GMT, Strominger JL, et al. Nomenclature for factors of the hla system, 1996 Immunologist. 6: 53-61. DOI: 10.1046/J.1423-0410.1997.7320105.X  0.44
1998 Allen FH, Amos DB, Batchelor JR, Bodmer WF, Ceppellini R, Dausset J, Owen D, Payne R, Van Rood JJ, Shulman NR, Terasaki PI, Trnka Z, Walford L. Nomenclature for factors of the HL-A system Immunologist. 6: 29-32.  0.44
1998 Beck NE, Tomlinson IPM, Homfray T, Hodgson SV, Haracopos CJ, Bodmer WF. Failure to satisfy the Amsterdam criteria for diagnosis of HPNCC should not preclude 'at risk' families from predictive genetic testing Surgical Research Communications. 19: 206.  0.44
1997 Durbin H, Novelli MR, Bodmer WF. Genomic and cDNA sequence analysis of the cell matrix adhesion regulator gene. Proceedings of the National Academy of Sciences of the United States of America. 94: 14578-83. PMID 9405655 DOI: 10.1073/pnas.94.26.14578  0.44
1997 Cavalli-Sforza LL, Bodmer W, Dausset J. Support for genetic diversity project. Nature. 390: 221. PMID 9384364 DOI: 10.1038/36711  0.44
1997 Marsh DJ, Roth S, Lunetta KL, Hemminki A, Dahia PL, Sistonen P, Zheng Z, Caron S, van Orsouw NJ, Bodmer WF, Cottrell SE, Dunlop MG, Eccles D, Hodgson SV, Järvinen H, et al. Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome. Cancer Research. 57: 5017-21. PMID 9371495  0.44
1997 Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Charron D, Dupont B, Erlich HA, Fauchet R, Mach B, Mayr WR, Parham P, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA system, 1996. Vox Sanguinis. 73: 105-30. PMID 9304780  0.44
1997 Bodmer WF. Genetic diversity and disease susceptibility. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 352: 1045-50. PMID 9304669 DOI: 10.1098/rstb.1997.0083  0.44
1997 Beck NE, Tomlinson IP, Homfray TF, Frayling IM, Hodgson SV, Bodmer WF. Frequency of germline hereditary non-polyposis colorectal cancer gene mutations in patients with multiple or early onset colorectal adenomas. Gut. 41: 235-8. PMID 9301504  0.44
1997 Ilyas M, Tomlinson IP, Rowan A, Pignatelli M, Bodmer WF. Beta-catenin mutations in cell lines established from human colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 94: 10330-4. PMID 9294210 DOI: 10.1073/pnas.94.19.10330  0.44
1997 Frayling IM, Bodmer WF, Tomlinson IP. Allele loss in colorectal cancer at the Cowden disease/juvenile polyposis locus on 10q. Cancer Genetics and Cytogenetics. 97: 64-9. PMID 9242220 DOI: 10.1016/S0165-4608(97)00011-3  0.44
1997 Ilyas M, Tomlinson IP, Hanby A, Talbot IC, Bodmer WF. Allele loss, replication errors and loss of expression of E-cadherin in colorectal cancers. Gut. 40: 654-9. PMID 9203946  0.44
1997 Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Charron D, Dupont B, Erlich HA, Fauchet R, Mach B, Mayr WR, Parham P, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA System, 1996. Human Immunology. 53: 98-128. PMID 9127153 DOI: 10.1016/S0198-8859(97)00031-1  0.44
1997 Tomlinson IP, Beck NE, Williamson J, Harocopos CJ, Mitchell VE, Hodgson SV, Bodmer WF. Clinical features and molecular analysis of a family with multiple colon tumours and reduced plasminogen activator activity. International Journal of Colorectal Disease. 12: 1-3. PMID 9112141 DOI: 10.1007/s003840050068  0.44
1997 Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Charron D, Dupont B, Erlich HA, Fauchet R, Mach B, Mayr WR, Parham P, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA system, 1996. European Journal of Immunogenetics : Official Journal of the British Society For Histocompatibility and Immunogenetics. 24: 105-51. PMID 9104581  0.44
1997 Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Charron D, Dupont B, Erlich HA, Fauchet R, Mach B, Mayr WR, Parham P, Sasazuki T, Schreuder GM, Strominger JL, et al. Nomenclature for factors of the HLA system, 1996. Tissue Antigens. 49: 297-321. PMID 9098945  0.44
1997 Bodmer WF. HLA: what's in a name? A commentary on HLA nomenclature development over the years. Tissue Antigens. 49: 293-6. PMID 9098944  0.44
1997 Wasan HS, Novelli M, Bee J, Bodmer WF. Dietary fat influences on polyp phenotype in multiple intestinal neoplasia mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 3308-13. PMID 9096389 DOI: 10.1073/pnas.94.7.3308  0.44
1997 Tomlinson IP, Hampson R, Karran P, Bodmer WF. DNA mismatch repair in lymphoblastoid cells from hereditary non-polyposis colorectal cancer (HNPCC) patients is normal under conditions of rapid cell division and increased mutational load. Mutation Research. 383: 177-82. PMID 9088350 DOI: 10.1016/S0921-8777(96)00058-4  0.44
1997 Rowan AJ, Bodmer WF. Introduction of a myc reporter tag to improve the quality of mutation detection using the protein truncation test. Human Mutation. 9: 172-6. PMID 9067758 DOI: 10.1002/(SICI)1098-1004(1997)9:2<172::AID-HUMU10>3.0.CO;2-#  0.44
1997 Beck NE, Tomlinson IP, Homfray T, Hodgson SV, Harocopos CJ, Bodmer WF. Genetic testing is important in families with a history suggestive of hereditary non-polyposis colorectal cancer even if the Amsterdam criteria are not fulfilled. The British Journal of Surgery. 84: 233-7. PMID 9052445 DOI: 10.1002/bjs.1800840228  0.44
1997 Beck NE, Tomlinson IP, Homfray T, Frayling I, Hodgson SV, Harocopos C, Bodmer WF. Use of SSCP analysis to identify germline mutations in HNPCC families fulfilling the Amsterdam criteria. Human Genetics. 99: 219-24. PMID 9048925 DOI: 10.1007/s004390050343  0.44
1997 Bodmer W. The somatic evolution of cancer. The Harveian Oration of 1996. Journal of the Royal College of Physicians of London. 31: 82-9. PMID 9044206  0.44
1997 Tomlinson IP, Beck NE, Homfray T, Harocopos CJ, Bodmer WF. Germline HNPCC gene variants have little influence on the risk for sporadic colorectal cancer. Journal of Medical Genetics. 34: 39-42. PMID 9032648  0.44
1997 Whitelaw SC, Murday VA, Tomlinson IP, Thomas HJ, Cottrell S, Ginsberg A, Bukofzer S, Hodgson SV, Skudowitz RB, Jass JR, Talbot IC, Northover JM, Bodmer WF, Solomon E. Clinical and molecular features of the hereditary mixed polyposis syndrome. Gastroenterology. 112: 327-34. PMID 9024286 DOI: 10.1053/gast.1997.v112.pm9024286  0.44
1997 Tomlinson IP, Bodmer WF. Modelling the consequences of interactions between tumour cells. British Journal of Cancer. 75: 157-60. PMID 9010019  0.44
1997 Hemminki A, Tomlinson I, Markie D, Järvinen H, Sistonen P, Björkqvist AM, Knuutila S, Salovaara R, Bodmer W, Shibata D, de la Chapelle A, Aaltonen LA. Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis. Nature Genetics. 15: 87-90. PMID 8988175 DOI: 10.1038/Ng0197-87  0.44
1997 Tomlinson IPM, Beck NE, Homfray T, Harocopos CJ, Adams M, Hodgson SV, Markie D, Bodmer WF. Molecular and clinico-pathological features of two families with the HNPCC syndrome and unusual phenotypes Gi Cancer. 2: 89-98.  0.44
1997 Novelli MR, Williamson JA, Tomlinson IPM, Elia G, Hodgson SV, Talbot IC, Bodmer WF, Wright NA. The origin of colorectal neoplasms: Clues to the origin of human cancer Cell Proliferation. 30: 448.  0.44
1996 Bicknell DC, Kaklamanis L, Hampson R, Bodmer WF, Karran P. Selection for beta 2-microglobulin mutation in mismatch repair-defective colorectal carcinomas. Current Biology : Cb. 6: 1695-7. PMID 8994836  0.44
1996 Tomlinson IP, Beck NE, Bodmer WF. Allele loss on chromosome 11q and microsatellite instability in malignant melanoma. European Journal of Cancer (Oxford, England : 1990). 32: 1797-802. PMID 8983292  0.44
1996 Tomlinson IP, Novelli MR, Bodmer WF. The mutation rate and cancer. Proceedings of the National Academy of Sciences of the United States of America. 93: 14800-3. PMID 8962135 DOI: 10.1073/pnas.93.25.14800  0.44
1996 Tomlinson IP, Ilyas M, Bodmer WF. Allele loss occurs frequently at hMLH1, but rarely at hMSH2, in sporadic colorectal cancers with microsatellite instability. British Journal of Cancer. 74: 1514-7. PMID 8932328  0.44
1996 Tomlinson IP, Beck NE, Neale K, Bodmer WF. Variants at the secretory phospholipase A2 (PLA2G2A) locus: analysis of associations with familial adenomatous polyposis and sporadic colorectal tumours. Annals of Human Genetics. 60: 369-76. PMID 8912789  0.44
1996 Ilyas M, Tomlinson IP, Hanby AM, Yao T, Bodmer WF, Talbot IC. Bcl-2 expression in colorectal tumors: evidence of different pathways in sporadic and ulcerative-colitis-associated carcinomas. The American Journal of Pathology. 149: 1719-26. PMID 8909260  0.44
1996 Bodmer WF, Tomlinson I. Population genetics of tumours. Ciba Foundation Symposium. 197: 181-9; discussion 18. PMID 8827374  0.44
1996 Browning M, Petronzelli F, Bicknell D, Krausa P, Rowan A, Tonks S, Murray N, Bodmer J, Bodmer W. Mechanisms of loss of HLA class I expression on colorectal tumor cells. Tissue Antigens. 47: 364-71. PMID 8795136 DOI: 10.1111/J.1399-0039.1996.Tb02571.X  0.44
1996 Tomlinson IP, Neale K, Talbot IC, Spigelman AD, Williams CB, Phillips RK, Bodmer WF. A modifying locus for familial adenomatous polyposis may be present on chromosome 1p35-p36. Journal of Medical Genetics. 33: 268-73. PMID 8730279  0.44
1996 Thomas HJ, Whitelaw SC, Cottrell SE, Murday VA, Tomlinson IP, Markie D, Jones T, Bishop DT, Hodgson SV, Sheer D, Northover JM, Talbot IC, Solomon E, Bodmer WF. Genetic mapping of hereditary mixed polyposis syndrome to chromosome 6q. American Journal of Human Genetics. 58: 770-6. PMID 8644741  0.44
1996 Novelli MR, Williamson JA, Tomlinson IP, Elia G, Hodgson SV, Talbot IC, Bodmer WF, Wright NA. Polyclonal origin of colonic adenomas in an XO/XY patient with FAP. Science (New York, N.Y.). 272: 1187-90. PMID 8638166  0.44
1996 Bodmer W. Genetic testing and insurance. Nature. 380: 384-6. PMID 8602232 DOI: 10.1038/380384A0  0.44
1995 Browning MJ, Madrigal JA, Krausa P, Kowalski H, Allsopp CE, Little AM, Turner S, Adams EJ, Arnett KL, Bodmer WF. The HLA-A,B,C genotype of the class I negative cell line Daudi reveals novel HLA-A and -B alleles. Tissue Antigens. 45: 177-87. PMID 7761977 DOI: 10.1111/J.1399-0039.1995.Tb02437.X  0.44
1994 Smith-Ravin J, Pack K, Hodgson S, Tay SK, Phillips R, Bodmer W. APC mutation associated with late onset of familial adenomatous polyposis. Journal of Medical Genetics. 31: 888-90. PMID 7853377 DOI: 10.1136/Jmg.31.11.888  0.44
1994 Hall NR, Taylor GR, Finan PJ, Kolodner RD, Bodmer WF, Cottrell SE, Frayling I, Bishop DT. Intron splice acceptor site sequence variation in the hereditary non-polyposis colorectal cancer gene hMSH2. European Journal of Cancer (Oxford, England : 1990). 30: 1550-2. PMID 7833117 DOI: 10.1016/0959-8049(94)00326-Z  0.44
1994 Nugent KP, Phillips RK, Hodgson SV, Cottrell S, Smith-Ravin J, Pack K, Bodmer WF. Phenotypic expression in familial adenomatous polyposis: partial prediction by mutation analysis. Gut. 35: 1622-3. PMID 7828985  0.44
1994 Durbin H, Young S, Stewart LM, Wrba F, Rowan AJ, Snary D, Bodmer WF. An epitope on carcinoembryonic antigen defined by the clinically relevant antibody PR1A3. Proceedings of the National Academy of Sciences of the United States of America. 91: 4313-7. PMID 7514303  0.44
1993 Markie D, Ragoussis J, Senger G, Rowan A, Sansom D, Trowsdale J, Sheer D, Bodmer WF. New vector for transfer of yeast artificial chromosomes to mammalian cells. Somatic Cell and Molecular Genetics. 19: 161-9. PMID 8511673 DOI: 10.1007/BF01233531  0.44
1993 Ward JR, Cottrell S, Thomas HJ, Jones TA, Howe CM, Hampton GM, Deaven L, Sheer D, Bodmer WF, Solomon E. A long-range restriction map of human chromosome 5q21-q23. Genomics. 17: 15-24. PMID 8104865 DOI: 10.1006/geno.1993.1277  0.44
1992 Markie D, Jones TA, Sheer D, Bodmer WF. A somatic cell hybrid panel for regional mapping of human chromosome 18. Genomics. 14: 431-6. PMID 1427858 DOI: 10.1016/S0888-7543(05)80237-X  0.44
1991 Williams SV, Jones TA, Cottrell S, Zehetner G, Varesco L, Ward T, Thomas H, Lawson PA, Solomon E, Bodmer WF. Fine mapping of probes in the adenomatous polyposis coli region of chromosome 5 by in situ hybridization. Genes, Chromosomes & Cancer. 3: 382-9. PMID 1665706 DOI: 10.1002/gcc.2870030509  0.44
1989 Varesco L, Thomas HJ, Cottrell S, Murday V, Fennell SJ, Williams S, Searle S, Sheer D, Bodmer WF, Frischauf AM. CpG island clones from a deletion encompassing the gene for adenomatous polyposis coli. Proceedings of the National Academy of Sciences of the United States of America. 86: 10118-22. PMID 2557613 DOI: 10.1073/pnas.86.24.10118  0.44
1987 Bodmer J, Bodmer W, Heyes J, So A, Tonks S, Trowsdale J, Young J. Identification of HLA-DP polymorphism with DP alpha and DP beta probes and monoclonal antibodies: correlation with primed lymphocyte typing. Proceedings of the National Academy of Sciences of the United States of America. 84: 4596-600. PMID 2885841 DOI: 10.1073/Pnas.84.13.4596  0.44
1979 Thomson G, Bodmer W. HLA haplotype associations with disease. Tissue Antigens. 13: 91-102. PMID 87027 DOI: 10.1111/J.1399-0039.1979.Tb01144.X  0.48
1964 PAYNE R, TRIPP M, WEIGLE J, BODMER W, BODMER J. A NEW LEUKOCYTE ISOANTIGEN SYSTEM IN MAN. Cold Spring Harbor Symposia On Quantitative Biology. 29: 285-295. PMID 14278475 DOI: 10.1101/Sqb.1964.029.01.031  0.44
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