Bryan T. MacDonald, Ph.D. - Publications

2004 University of Michigan, Ann Arbor, Ann Arbor, MI 
Genetics, Animal Physiology Biology, Molecular Biology

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Zhang X, MacDonald BT, Gao H, Shamashkin M, Coyle AJ, Martinez RX, He X. Characterization of Tiki, a new family of WNT-specific metalloproteases. The Journal of Biological Chemistry. PMID 26631728 DOI: 10.1074/jbc.M115.677807  0.52
2015 Niziolek PJ, MacDonald BT, Kedlaya R, Zhang M, Bellido T, He X, Warman ML, Robling AG. High-bone-mass causing mutant LRP5 receptors are resistant to endogenous inhibitors in vivo. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 25808845 DOI: 10.1002/jbmr.2514  0.52
2015 Zhang X, Cheong SM, Amado NG, Reis AH, MacDonald BT, Zebisch M, Jones EY, Abreu JG, He X. Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation. Developmental Cell. 32: 719-30. PMID 25771893 DOI: 10.1016/j.devcel.2015.02.014  0.52
2014 Cui Y, Niziolek PJ, MacDonald BT, Alenina N, Matthes S, Jacobsen CM, Conlon RA, Brommage R, Powell DR, He X, Bader M, Williams BO, Warman ML, Robling AG. Reply to Lrp5 regulation of bone mass and gut serotonin synthesis. Nature Medicine. 20: 1229-30. PMID 25375917 DOI: 10.1038/nm.3697  0.52
2014 Reis AH, Macdonald BT, Feistel K, Brito JM, Amado NG, Xu C, Abreu JG, He X. Expression and evolution of the Tiki1 and Tiki2 genes in vertebrates. The International Journal of Developmental Biology. 58: 355-62. PMID 25354456 DOI: 10.1387/ijdb.140106ja  0.52
2014 MacDonald BT, Hien A, Zhang X, Iranloye O, Virshup DM, Waterman ML, He X. Disulfide bond requirements for active Wnt ligands. The Journal of Biological Chemistry. 289: 18122-36. PMID 24841207 DOI: 10.1074/jbc.M114.575027  0.52
2014 Wang L, Shalek AK, Lawrence M, Ding R, Gaublomme JT, Pochet N, Stojanov P, Sougnez C, Shukla SA, Stevenson KE, Zhang W, Wong J, Sievers QL, MacDonald BT, Vartanov AR, et al. Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL. Blood. 124: 1089-98. PMID 24778153 DOI: 10.1182/blood-2014-01-552067  0.52
2014 Guo C, Sun Y, Guo C, MacDonald BT, Borer JG, Li X. Dkk1 in the peri-cloaca mesenchyme regulates formation of anorectal and genitourinary tracts. Developmental Biology. 385: 41-51. PMID 24479159 DOI: 10.1016/j.ydbio.2013.10.016  0.52
2013 Zebisch M, Xu Y, Krastev C, MacDonald BT, Chen M, Gilbert RJ, He X, Jones EY. Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin. Nature Communications. 4: 2787. PMID 24225776 DOI: 10.1038/ncomms3787  0.52
2013 Kim SE, Huang H, Zhao M, Zhang X, Zhang A, Semonov MV, MacDonald BT, Zhang X, Garcia Abreu J, Peng L, He X. Wnt stabilization of β-catenin reveals principles for morphogen receptor-scaffold assemblies. Science (New York, N.Y.). 340: 867-70. PMID 23579495 DOI: 10.1126/science.1232389  0.52
2013 Macaulay IC, Thon JN, Tijssen MR, Steele BM, MacDonald BT, Meade G, Burns P, Rendon A, Salunkhe V, Murphy RP, Bennett C, Watkins NA, He X, Fitzgerald DJ, Italiano JE, et al. Canonical Wnt signaling in megakaryocytes regulates proplatelet formation. Blood. 121: 188-96. PMID 23160460 DOI: 10.1182/blood-2012-03-416875  0.52
2012 MacDonald BT, He X. Frizzled and LRP5/6 receptors for Wnt/β-catenin signaling. Cold Spring Harbor Perspectives in Biology. 4. PMID 23209147 DOI: 10.1101/cshperspect.a007880  0.52
2012 Zhang X, Abreu JG, Yokota C, MacDonald BT, Singh S, Coburn KL, Cheong SM, Zhang MM, Ye QZ, Hang HC, Steen H, He X. Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation. Cell. 149: 1565-77. PMID 22726442 DOI: 10.1016/j.cell.2012.04.039  0.52
2012 MacDonald BT, He X. A finger on the pulse of Wnt receptor signaling. Cell Research. 22: 1410-2. PMID 22688894 DOI: 10.1038/cr.2012.91  0.52
2011 Chen S, Bubeck D, MacDonald BT, Liang WX, Mao JH, Malinauskas T, Llorca O, Aricescu AR, Siebold C, He X, Jones EY. Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling. Developmental Cell. 21: 848-61. PMID 22000855 DOI: 10.1016/j.devcel.2011.09.007  0.52
2011 MacDonald BT, Semenov MV, Huang H, He X. Dissecting molecular differences between Wnt coreceptors LRP5 and LRP6. Plos One. 6: e23537. PMID 21887268 DOI: 10.1371/journal.pone.0023537  0.52
2011 Cui Y, Niziolek PJ, MacDonald BT, Zylstra CR, Alenina N, Robinson DR, Zhong Z, Matthes S, Jacobsen CM, Conlon RA, Brommage R, Liu Q, Mseeh F, Powell DR, Yang QM, et al. Lrp5 functions in bone to regulate bone mass. Nature Medicine. 17: 684-91. PMID 21602802 DOI: 10.1038/nm.2388  0.52
2009 MacDonald BT, Tamai K, He X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Developmental Cell. 17: 9-26. PMID 19619488 DOI: 10.1016/j.devcel.2009.06.016  0.52
2008 MacDonald BT, Yokota C, Tamai K, Zeng X, He X. Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6. The Journal of Biological Chemistry. 283: 16115-23. PMID 18362152 DOI: 10.1074/jbc.M800327200  0.52
2007 Semenov MV, Habas R, Macdonald BT, He X. SnapShot: Noncanonical Wnt Signaling Pathways. Cell. 131: 1378. PMID 18160045 DOI: 10.1016/j.cell.2007.12.011  0.52
2007 Macdonald BT, Semenov MV, He X. SnapShot: Wnt/beta-catenin signaling. Cell. 131: 1204. PMID 18083108 DOI: 10.1016/j.cell.2007.11.036  0.52
2007 MacDonald BT, Joiner DM, Oyserman SM, Sharma P, Goldstein SA, He X, Hauschka PV. Bone mass is inversely proportional to Dkk1 levels in mice. Bone. 41: 331-9. PMID 17613296 DOI: 10.1016/j.bone.2007.05.009  0.52
2007 Joiner DM, MacDonald BT, He X, Hauschka PV, Goldstein SA. Reduction of the WnT inhibitor Dkk1 correlates with improved bone mechanical and morphological properties in mice Proceedings of the Asme Summer Bioengineering Conference 2007, Sbc 2007. 859-860.  0.52
2004 Spampanato J, Kearney JA, de Haan G, McEwen DP, Escayg A, Aradi I, MacDonald BT, Levin SI, Soltesz I, Benna P, Montalenti E, Isom LL, Goldin AL, Meisler MH. A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for beta subunit interaction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10022-34. PMID 15525788 DOI: 10.1523/JNEUROSCI.2034-04.2004  0.52
2004 Adamska M, MacDonald BT, Sarmast ZH, Oliver ER, Meisler MH. En1 and Wnt7a interact with Dkk1 during limb development in the mouse. Developmental Biology. 272: 134-44. PMID 15242796 DOI: 10.1016/j.ydbio.2004.04.026  0.52
2004 MacDonald BT, Adamska M, Meisler MH. Hypomorphic expression of Dkk1 in the doubleridge mouse: dose dependence and compensatory interactions with Lrp6. Development (Cambridge, England). 131: 2543-52. PMID 15115753 DOI: 10.1242/dev.01126  0.52
2003 Adamska M, MacDonald BT, Meisler MH. Doubleridge, a mouse mutant with defective compaction of the apical ectodermal ridge and normal dorsal-ventral patterning of the limb. Developmental Biology. 255: 350-62. PMID 12648495 DOI: 10.1016/S0012-1606(02)00114-8  0.52
2003 Weiss LA, Escayg A, Kearney JA, Trudeau M, MacDonald BT, Mori M, Reichert J, Buxbaum JD, Meisler MH. Sodium channels SCN1A, SCN2A and SCN3A in familial autism. Molecular Psychiatry. 8: 186-94. PMID 12610651 DOI: 10.1038/  0.52
2002 Meisler MH, Kearney JA, Sprunger LK, MacDonald BT, Buchner DA, Escayg A. Mutations of voltage-gated sodium channels in movement disorders and epilepsy. Novartis Foundation Symposium. 241: 72-81; discussion 82. PMID 11771652  0.52
2001 Meisler MH, Kearney J, Escayg A, MacDonald BT, Sprunger LK. Sodium channels and neurological disease: insights from Scn8a mutations in the mouse. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 7: 136-45. PMID 11496924  0.52
2001 Escayg A, Heils A, MacDonald BT, Haug K, Sander T, Meisler MH. A novel SCN1A mutation associated with generalized epilepsy with febrile seizures plus--and prevalence of variants in patients with epilepsy. American Journal of Human Genetics. 68: 866-73. PMID 11254445 DOI: 10.1086/319524  0.52
2000 Escayg A, MacDonald BT, Meisler MH, Baulac S, Huberfeld G, An-Gourfinkel I, Brice A, LeGuern E, Moulard B, Chaigne D, Buresi C, Malafosse A. Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2. Nature Genetics. 24: 343-5. PMID 10742094 DOI: 10.1038/74159  0.52
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