| Year |
Citation |
Score |
| 2018 |
Ramsey IS, DeSimone JA. Otopetrin-1: A sour-tasting proton channel. The Journal of General Physiology. PMID 29483132 DOI: 10.1085/Jgp.201812003 |
0.317 |
|
| 2017 |
Qian J, Mummalaneni S, Phan TT, Heck GL, DeSimone JA, West D, Mahavadi S, Hojati D, Murthy KS, Rhyu MR, Spielman AI, Özdener MH, Lyall V. Cyclic-AMP regulates postnatal development of neural and behavioral responses to NaCl in rats. Plos One. 12: e0171335. PMID 28192441 DOI: 10.1371/Journal.Pone.0171335 |
0.788 |
|
| 2017 |
DeSimone JA. The dependence of the phasic response of the taste nerves on stimulus flow rate arises in the diffusion boundary layer region at the lingual surface: A convective-diffusion analysis Chemical Engineering Science. 168: 289-308. DOI: 10.1016/J.Ces.2017.04.034 |
0.355 |
|
| 2015 |
Ren ZJ, Mummalaneni S, Qian J, Baumgarten CM, DeSimone JA, Lyall V. Nicotinic Acetylcholine Receptor (nAChR) Dependent Chorda Tympani Taste Nerve Responses to Nicotine, Ethanol and Acetylcholine. Plos One. 10: e0127936. PMID 26039516 DOI: 10.1371/Journal.Pone.0127936 |
0.358 |
|
| 2015 |
DeSimone JA, Phan TH, Mummalaneni S, Rhyu MR, Heck GL, Lyall V. Regulatory Effects of Ca2+ and H+ on the Rat Chorda Tympani Response to NaCl and KCl. Chemical Senses. 40: 401-12. PMID 25953775 DOI: 10.1093/Chemse/Bjv022 |
0.792 |
|
| 2014 |
Kendig DM, Hurst NR, Bradley ZL, Mahavadi S, Kuemmerle JF, Lyall V, DeSimone J, Murthy KS, Grider JR. Activation of the umami taste receptor (T1R1/T1R3) initiates the peristaltic reflex and pellet propulsion in the distal colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. 307: G1100-7. PMID 25324508 DOI: 10.1152/Ajpgi.00251.2014 |
0.361 |
|
| 2014 |
Mummalaneni S, Qian J, Phan TH, Rhyu MR, Heck GL, DeSimone JA, Lyall V. Effect of ENaC modulators on rat neural responses to NaCl. Plos One. 9: e98049. PMID 24839965 DOI: 10.1371/Journal.Pone.0098049 |
0.795 |
|
| 2013 |
Ren Z, Rhyu MR, Phan TH, Mummalaneni S, Murthy KS, Grider JR, DeSimone JA, Lyall V. TRPM5-dependent amiloride- and benzamil-insensitive NaCl chorda tympani taste nerve response. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G106-17. PMID 23639808 DOI: 10.1152/Ajpgi.00053.2013 |
0.5 |
|
| 2013 |
Dewis ML, Phan TH, Ren Z, Meng X, Cui M, Mummalaneni S, Rhyu MR, DeSimone JA, Lyall V. N-geranyl cyclopropyl-carboximide modulates salty and umami taste in humans and animal models. Journal of Neurophysiology. 109: 1078-90. PMID 23221408 DOI: 10.1152/Jn.00124.2012 |
0.471 |
|
| 2012 |
Desimone JA, Phan TH, Ren Z, Mummalaneni S, Lyall V. Changes in taste receptor cell [Ca2+]i modulate chorda tympani responses to bitter, sweet, and umami taste stimuli. Journal of Neurophysiology. 108: 3221-32. PMID 22993258 DOI: 10.1152/Jn.00129.2012 |
0.415 |
|
| 2012 |
Desimone JA, Ren Z, Phan TH, Heck GL, Mummalaneni S, Lyall V. Changes in taste receptor cell [Ca2+]i modulate chorda tympani responses to salty and sour taste stimuli. Journal of Neurophysiology. 108: 3206-20. PMID 22956787 DOI: 10.1152/Jn.00916.2011 |
0.773 |
|
| 2011 |
Coleman J, Williams A, Phan TH, Mummalaneni S, Melone P, Ren Z, Zhou H, Mahavadi S, Murthy KS, Katsumata T, DeSimone JA, Lyall V. Strain differences in the neural, behavioral, and molecular correlates of sweet and salty taste in naive, ethanol- and sucrose-exposed P and NP rats. Journal of Neurophysiology. 106: 2606-21. PMID 21849614 DOI: 10.1152/Jn.00196.2010 |
0.359 |
|
| 2011 |
DeSimone JA, Phan TH, Heck GL, Ren Z, Coleman J, Mummalaneni S, Melone P, Lyall V. Involvement of NADPH-dependent and cAMP-PKA sensitive H+ channels in the chorda tympani nerve responses to strong acids. Chemical Senses. 36: 389-403. PMID 21339339 DOI: 10.1093/Chemse/Bjq148 |
0.793 |
|
| 2011 |
Sturz GR, Phan TH, Mummalaneni S, Ren Z, DeSimone JA, Lyall V. The K+-H+ exchanger, nigericin, modulates taste cell pH and chorda tympani taste nerve responses to acidic stimuli. Chemical Senses. 36: 375-88. PMID 21257734 DOI: 10.1093/Chemse/Bjq146 |
0.499 |
|
| 2010 |
Lyall V, Phan TH, Ren Z, Mummalaneni S, Melone P, Mahavadi S, Murthy KS, DeSimone JA. Regulation of the putative TRPV1t salt taste receptor by phosphatidylinositol 4,5-bisphosphate. Journal of Neurophysiology. 103: 1337-49. PMID 20032236 DOI: 10.1152/Jn.00883.2009 |
0.453 |
|
| 2009 |
Lyall V, Phan TH, Mummalaneni S, Melone P, Mahavadi S, Murthy KS, DeSimone JA. Regulation of the benzamil-insensitive salt taste receptor by intracellular Ca2+, protein kinase C, and calcineurin. Journal of Neurophysiology. 102: 1591-605. PMID 19553475 DOI: 10.1152/Jn.91301.2008 |
0.422 |
|
| 2009 |
Oliveira-Maia AJ, Stapleton-Kotloski JR, Lyall V, Phan TH, Mummalaneni S, Melone P, Desimone JA, Nicolelis MA, Simon SA. Nicotine activates TRPM5-dependent and independent taste pathways. Proceedings of the National Academy of Sciences of the United States of America. 106: 1596-601. PMID 19164511 DOI: 10.1073/Pnas.0810184106 |
0.352 |
|
| 2008 |
Katsumata T, Nakakuki H, Tokunaga C, Fujii N, Egi M, Phan TH, Mummalaneni S, DeSimone JA, Lyall V. Effect of Maillard reacted peptides on human salt taste and the amiloride-insensitive salt taste receptor (TRPV1t). Chemical Senses. 33: 665-80. PMID 18603652 DOI: 10.1093/Chemse/Bjn033 |
0.5 |
|
| 2007 |
Lyall V, Phan TH, Mummalaneni S, Mansouri M, Heck GL, Kobal G, DeSimone JA. Effect of nicotine on chorda tympani responses to salty and sour stimuli. Journal of Neurophysiology. 98: 1662-74. PMID 17615133 DOI: 10.1152/Jn.00366.2007 |
0.792 |
|
| 2007 |
Treesukosol Y, Lyall V, Heck GL, DeSimone JA, Spector AC. A psychophysical and electrophysiological analysis of salt taste in Trpv1 null mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 292: R1799-809. PMID 17234959 DOI: 10.1152/Ajpregu.00587.2006 |
0.767 |
|
| 2006 |
DeSimone JA, Lyall V. Taste receptors in the gastrointestinal tract III. Salty and sour taste: sensing of sodium and protons by the tongue. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G1005-10. PMID 16809639 DOI: 10.1152/Ajpgi.00235.2006 |
0.496 |
|
| 2006 |
Lyall V, Pasley H, Phan TH, Mummalaneni S, Heck GL, Vinnikova AK, DeSimone JA. Intracellular pH modulates taste receptor cell volume and the phasic part of the chorda tympani response to acids. The Journal of General Physiology. 127: 15-34. PMID 16380442 DOI: 10.1085/Jgp.200509384 |
0.785 |
|
| 2005 |
Lyall V, Heck GL, Phan TH, Mummalaneni S, Malik SA, Vinnikova AK, Desimone JA. Ethanol modulates the VR-1 variant amiloride-insensitive salt taste receptor. II. Effect on chorda tympani salt responses. The Journal of General Physiology. 125: 587-600. PMID 15928404 DOI: 10.1085/Jgp.200509264 |
0.784 |
|
| 2005 |
Lyall V, Heck GL, Phan TH, Mummalaneni S, Malik SA, Vinnikova AK, DeSimone JA. Ethanol modulates the VR-1 variant amiloride-insensitive salt taste receptor. I. Effect on TRC volume and Na+ flux. The Journal of General Physiology. 125: 569-85. PMID 15928403 DOI: 10.1085/Jgp.200409213 |
0.781 |
|
| 2005 |
Lyall V, Heck GL, Vinnikova AK, Ghosh S, Phan TH, Desimone JA. A novel vanilloid receptor-1 (VR-1) variant mammalian salt taste receptor. Chemical Senses. 30: i42-3. PMID 15738186 DOI: 10.1093/Chemse/Bjh104 |
0.733 |
|
| 2004 |
Lyall V, Heck GL, Vinnikova AK, Ghosh S, Phan TH, Alam RI, Russell OF, Malik SA, Bigbee JW, DeSimone JA. The mammalian amiloride-insensitive non-specific salt taste receptor is a vanilloid receptor-1 variant. The Journal of Physiology. 558: 147-59. PMID 15146042 DOI: 10.1113/Jphysiol.2004.065656 |
0.782 |
|
| 2004 |
Lyall V, Alam RI, Malik SA, Phan TH, Vinnikova AK, Heck GL, DeSimone JA. Basolateral Na+-H+ exchanger-1 in rat taste receptor cells is involved in neural adaptation to acidic stimuli. The Journal of Physiology. 556: 159-73. PMID 14724181 DOI: 10.1113/Jphysiol.2003.057745 |
0.803 |
|
| 2004 |
Vinnikova AK, Alam RI, Malik SA, Ereso GL, Feldman GM, McCarty JM, Knepper MA, Heck GL, DeSimone JA, Lyall V. Na+-H+ exchange activity in taste receptor cells. Journal of Neurophysiology. 91: 1297-313. PMID 14602837 DOI: 10.1152/Jn.00809.2003 |
0.768 |
|
| 2003 |
Feldman GM, Mogyorosi A, Heck GL, DeSimone JA, Santos CR, Clary RA, Lyall V. Salt-evoked lingual surface potential in humans. Journal of Neurophysiology. 90: 2060-4. PMID 12736236 DOI: 10.1152/Jn.00158.2003 |
0.767 |
|
| 2002 |
Lyall V, Alam RI, Phan TH, Russell OF, Malik SA, Heck GL, DeSimone JA. Modulation of rat chorda tympani NaCl responses and intracellular Na+ activity in polarized taste receptor cells by pH. The Journal of General Physiology. 120: 793-815. PMID 12451050 DOI: 10.1085/Jgp.20028656 |
0.793 |
|
| 2002 |
Lyall V, Alam RI, Phan TH, Phan DQ, Heck GL, DeSimone JA. Excitation and adaptation in the detection of hydrogen ions by taste receptor cells: a role for cAMP and Ca(2+). Journal of Neurophysiology. 87: 399-408. PMID 11784758 DOI: 10.1152/Jn.00331.2001 |
0.796 |
|
| 2001 |
DeSimone JA, Lyall V, Heck GL, Feldman GM. Acid detection by taste receptor cells. Respiration Physiology. 129: 231-45. PMID 11738657 DOI: 10.1016/S0034-5687(01)00293-6 |
0.773 |
|
| 2001 |
DeSimone JA, Lyall V, Heck GL, Phan TH, Alam RI, Feldman GM, Buch RM. A novel pharmacological probe links the amiloride-insensitive NaCl, KCl, and NH(4)Cl chorda tympani taste responses. Journal of Neurophysiology. 86: 2638-41. PMID 11698552 DOI: 10.1152/Jn.2001.86.5.2638 |
0.802 |
|
| 2001 |
Lyall V, Alam RI, Phan DQ, Ereso GL, Phan TH, Malik SA, Montrose MH, Chu S, Heck GL, Feldman GM, DeSimone JA. Decrease in rat taste receptor cell intracellular pH is the proximate stimulus in sour taste transduction. American Journal of Physiology. Cell Physiology. 281: C1005-13. PMID 11502578 DOI: 10.1152/Ajpcell.2001.281.3.C1005 |
0.777 |
|
| 2000 |
Hendricks SJ, Stewart RE, Heck GL, DeSimone JA, Hill DL. Development of rat chorda tympani sodium responses: evidence for age-dependent changes in global amiloride-sensitive Na(+) channel kinetics. Journal of Neurophysiology. 84: 1531-44. PMID 10980025 DOI: 10.1152/Jn.2000.84.3.1531 |
0.815 |
|
| 1999 |
Lyall V, Heck GL, DeSimone JA, Feldman GM. Effects of osmolarity on taste receptor cell size and function. The American Journal of Physiology. 277: C800-13. PMID 10516110 DOI: 10.1152/Ajpcell.1999.277.4.C800 |
0.793 |
|
| 1999 |
Delwiche JF, Halpern BP, Desimone JA. Anion size of sodium salts and simple taste reaction times. Physiology & Behavior. 66: 27-32. PMID 10222469 DOI: 10.1016/S0031-9384(98)00273-X |
0.398 |
|
| 1998 |
Stewart RE, Lyall V, Feldman GM, Heck GL, DeSimone JA. Acid-induced responses in hamster chorda tympani and intracellular pH tracking by taste receptor cells. American Journal of Physiology. Cell Physiology. 275: C227-C238. PMID 29591172 DOI: 10.1152/ajpcell.1998.275.1.C227 |
0.8 |
|
| 1998 |
Stewart RE, Lyall V, Feldman GM, Heck GL, DeSimone JA. Acid-induced responses in hamster chorda tympani and intracellular pH tracking by taste receptor cells. The American Journal of Physiology. 275: C227-38. PMID 9688854 DOI: 10.1152/Ajpcell.1998.275.1.C227 |
0.826 |
|
| 1998 |
Kloub MA, Heck GL, DeSimone JA. Self-inhibition in Ca2+ -evoked taste responses: a novel tool for functional dissection of salt taste transduction mechanisms. Journal of Neurophysiology. 79: 911-21. PMID 9463452 DOI: 10.1152/Jn.1998.79.2.911 |
0.785 |
|
| 1997 |
Lyall V, Feldman GM, Heck GL, DeSimone JA. Effects of extracellular pH, PCO2, and HCO3- on intracellular pH in isolated rat taste buds. The American Journal of Physiology. 273: C1008-19. PMID 9316422 DOI: 10.1152/Ajpcell.1997.273.3.C1008 |
0.737 |
|
| 1997 |
Kloub MA, Heck GL, DeSimone JA. Chorda tympani responses under lingual voltage clamp: implications for NH4 salt taste transduction. Journal of Neurophysiology. 77: 1393-406. PMID 9084605 DOI: 10.1152/Jn.1997.77.3.1393 |
0.808 |
|
| 1997 |
Stewart RE, DeSimone JA, Hill DL. New perspectives in a gustatory physiology: transduction, development, and plasticity. The American Journal of Physiology. 272: C1-26. PMID 9038806 DOI: 10.1152/Ajpcell.1997.272.1.C1 |
0.615 |
|
| 1996 |
Stewart RE, Heck GL, Desimone JA. Taste-mixture suppression: functional dissection of cellular and paracellular origins. Journal of Neurophysiology. 75: 2124-8. PMID 8734608 DOI: 10.1152/Jn.1996.75.5.2124 |
0.816 |
|
| 1995 |
DeSimone JA, Callaham EM, Heck GL. Chorda tympani taste response of rat to hydrochloric acid subject to voltage-clamped lingual receptive field. The American Journal of Physiology. 268: C1295-300. PMID 7762623 DOI: 10.1152/Ajpcell.1995.268.5.C1295 |
0.788 |
|
| 1994 |
Ye Q, Heck GL, DeSimone JA. Effects of voltage perturbation of the lingual receptive field on chorda tympani responses to Na+ and K+ salts in the rat: implications for gustatory transduction. The Journal of General Physiology. 104: 885-907. PMID 7876827 DOI: 10.1085/Jgp.104.5.885 |
0.792 |
|
| 1993 |
Ye Q, Heck GL, DeSimone JA. Voltage dependence of the rat chorda tympani response to Na+ salts: implications for the functional organization of taste receptor cells. Journal of Neurophysiology. 70: 167-78. PMID 8395573 DOI: 10.1152/Jn.1993.70.1.167 |
0.821 |
|
| 1993 |
Ye Q, Stewart RE, Heck GL, Hill DL, DeSimone JA. Dietary Na(+)-restriction prevents development of functional Na+ channels in taste cell apical membranes: proof by in vivo membrane voltage perturbation. Journal of Neurophysiology. 70: 1713-6. PMID 8283226 DOI: 10.1152/Jn.1993.70.4.1713 |
0.825 |
|
| 1993 |
DeSimone JA, Ye Q, Heck GL. Ion pathways in the taste bud and their significance for transduction. Ciba Foundation Symposium. 179: 218-29; discussion 2. PMID 7513272 |
0.8 |
|
| 1991 |
Ye Q, Heck GL, DeSimone JA. The anion paradox in sodium taste reception: resolution by voltage-clamp studies. Science (New York, N.Y.). 254: 724-6. PMID 1948054 DOI: 10.1126/Science.1948054 |
0.785 |
|
| 1990 |
Béhé P, DeSimone JA, Avenet P, Lindemann B. Membrane currents in taste cells of the rat fungiform papilla. Evidence for two types of Ca currents and inhibition of K currents by saccharin. The Journal of General Physiology. 96: 1061-84. PMID 2280253 DOI: 10.1085/jgp.96.5.1061 |
0.328 |
|
| 1989 |
Heck GL, Persaud KC, DeSimone JA. Direct measurement of translingual epithelial NaCl and KCl currents during the chorda tympani taste response. Biophysical Journal. 55: 843-57. PMID 2541822 DOI: 10.1016/S0006-3495(89)82884-X |
0.78 |
|
| 1988 |
Mierson S, DeSimone SK, Heck GL, DeSimone JA. Sugar-activated ion transport in canine lingual epithelium. Implications for sugar taste transduction. The Journal of General Physiology. 92: 87-111. PMID 3171536 DOI: 10.1085/Jgp.92.1.87 |
0.788 |
|
| 1988 |
Persaud KC, Heck GL, DeSimone SK, Getchell TV, DeSimone JA. Ion transport across the frog olfactory mucosa: the action of cyclic nucleotides on the basal and odorant-stimulated states. Biochimica Et Biophysica Acta. 944: 49-62. PMID 2843236 DOI: 10.1016/0005-2736(88)90315-X |
0.757 |
|
| 1987 |
Getchell ML, Zielinski B, DeSimone JA, Getchell TV. Odorant stimulation of secretory and neural processes in the salamander olfactory mucosa. Journal of Comparative Physiology. a, Sensory, Neural, and Behavioral Physiology. 160: 155-68. PMID 3572846 DOI: 10.1007/Bf00609723 |
0.397 |
|
| 1987 |
Persaud KC, DeSimone JA, Getchell ML, Heck GL, Getchell TV. Ion transport across the frog olfactory mucosa: the basal and odorant-stimulated states. Biochimica Et Biophysica Acta. 902: 65-79. PMID 2440480 DOI: 10.1016/0005-2736(87)90136-2 |
0.757 |
|
| 1986 |
Biber TU, DeSimone JA, Drewnowska K. Potential dependence of unidirectional chloride fluxes across isolated frog skin. Biochimica Et Biophysica Acta. 862: 27-38. PMID 3490276 DOI: 10.1016/0005-2736(86)90465-7 |
0.395 |
|
| 1985 |
Mierson S, Heck GL, DeSimone SK, Biber TU, DeSimone JA. The identity of the current carriers in canine lingual epithelium in vitro. Biochimica Et Biophysica Acta. 816: 283-93. PMID 4005245 DOI: 10.1016/0005-2736(85)90496-1 |
0.766 |
|
| 1985 |
DeSimone JA, Ferrell F. Analysis of amiloride inhibition of chorda tympani taste response of rat to NaCl. The American Journal of Physiology. 249: R52-61. PMID 2409823 |
0.341 |
|
| 1984 |
Heck GL, Mierson S, DeSimone JA. Salt taste transduction occurs through an amiloride-sensitive sodium transport pathway. Science (New York, N.Y.). 223: 403-5. PMID 6691151 DOI: 10.1126/Science.6691151 |
0.779 |
|
| 1984 |
Desimone JA, Heck GL, Mierson S, Desimone SK. The active ion transport properties of canine lingual epithelia in vitro. Implications for gustatory transduction. The Journal of General Physiology. 83: 633-56. PMID 6330275 DOI: 10.1085/Jgp.83.5.633 |
0.799 |
|
| 1984 |
Heck GL, DeSimone JA, Getchell TV. Evidence for electrogenic active ion transport across the frog olfactory mucosa in vitro Chemical Senses. 9: 273-283. DOI: 10.1093/Chemse/9.3.273 |
0.72 |
|
| 1981 |
DeSimone JA, Heck GL, DeSimone SK. Active ion transport in dog tongue: a possible role in taste. Science (New York, N.Y.). 214: 1039-41. PMID 7302576 DOI: 10.1126/Science.7302576 |
0.764 |
|
| 1980 |
Biber TU, Mullen TL, DeSimone JA. Effect of FeCl3 on ion transport in isolated frog skin. The Journal of Membrane Biology. 52: 133-9. PMID 6965989 DOI: 10.1007/Bf01869118 |
0.398 |
|
| 1980 |
Getchell TV, Heck GL, DeSimone JA, Price S. The location of olfactory receptor sites. Inferences from latency measurements. Biophysical Journal. 29: 397-411. PMID 6794658 DOI: 10.1016/S0006-3495(80)85142-3 |
0.736 |
|
| 1980 |
DeSimone JA, Heck GL. Surface active taste modifiers: a comparison of the physical and psychophysical properties of gymnemic acid and sodium lauryl sulfate Chemical Senses. 5: 317-330. DOI: 10.1093/Chemse/5.4.317 |
0.706 |
|
| 1980 |
Desimone JA, Heck GL. An analysis of the effects of stimulus transport and membrane charge on the salt, acid and water-response of mammals Chemical Senses. 5: 295-316. DOI: 10.1093/Chemse/5.4.295 |
0.736 |
|
| 1978 |
Desimone JA, Price S. An alternative to allosteric interactions as causes of sigmoid dose versus response curves. Application to glucose-induced secretion of insulin. Biochimica Et Biophysica Acta. 538: 120-6. PMID 339957 DOI: 10.1016/0304-4165(78)90256-8 |
0.312 |
|
| 1977 |
Price S, Desimone JA. Models of taste receptor cell stimulation Chemical Senses and Flavor. 2: 427-456. DOI: 10.1093/Chemse/2.4.427 |
0.313 |
|
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