Eero Castren - Publications

Affiliations: 
University of Helsinki, Helsingfors, Finland 

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Enkavi G, Girych M, Moliner R, Vattulainen I, Castrén E. TrkB transmembrane domain: bridging structural understanding with therapeutic strategy. Trends in Biochemical Sciences. PMID 38433044 DOI: 10.1016/j.tibs.2024.02.001  0.312
2024 Hellström S, Sajanti A, Srinath A, Bennett C, Girard R, Cao Y, Frantzén J, Koskimäki F, Falter J, Lyne SB, Rantamäki T, Takala R, Posti JP, Roine S, Puolitaival J, et al. Brain Plasticity Modulator p75 Neurotrophin Receptor in Human Urine after Different Acute Brain Injuries-A Prospective Cohort Study. Biomedicines. 12. PMID 38255217 DOI: 10.3390/biomedicines12010112  0.586
2023 Moliner R, Girych M, Brunello CA, Kovaleva V, Biojone C, Enkavi G, Antenucci L, Kot EF, Goncharuk SA, Kaurinkoski K, Kuutti M, Fred SM, Elsilä LV, Sakson S, Cannarozzo C, et al. Psychedelics promote plasticity by directly binding to BDNF receptor TrkB. Nature Neuroscience. 26: 1032-1041. PMID 37280397 DOI: 10.1038/s41593-023-01316-5  0.609
2023 Fred SM, Moliner R, Antila H, Engelhardt KA, Schlüter OM, Casarotto PC, Castrén E. TRKB interaction with PSD95 is associated with latency of fluoxetine and 2R,6R-hydroxynorketamine. The European Journal of Neuroscience. PMID 36876503 DOI: 10.1111/ejn.15952  0.31
2023 Biojone C, Casarotto P, Cannarozzo C, Fred SM, Herrera-Rodríguez R, Lesnikova A, Voipio M, Castrén E. nNOS-induced tyrosine nitration of TrkB impairs BDNF signaling and restrains neuronal plasticity. Progress in Neurobiology. 102413. PMID 36682419 DOI: 10.1016/j.pneurobio.2023.102413  0.305
2022 Casarotto P, Umemori J, Castrén E. BDNF receptor TrkB as the mediator of the antidepressant drug action. Frontiers in Molecular Neuroscience. 15: 1032224. PMID 36407765 DOI: 10.3389/fnmol.2022.1032224  0.339
2021 Castrén E, Monteggia L. Brain-Derived Neurotrophic Factor Signaling in Depression and Antidepressant Action. Biological Psychiatry. PMID 34053675 DOI: 10.1016/j.biopsych.2021.05.008  0.355
2021 Sahu MP, Pazos-Boubeta Y, Steinzeig A, Kaurinkoski K, Palmisano M, Borowecki O, Piepponen TP, Castrén E. Depletion of TrkB Receptors From Adult Serotonergic Neurons Increases Brain Serotonin Levels, Enhances Energy Metabolism and Impairs Learning and Memory. Frontiers in Molecular Neuroscience. 14: 616178. PMID 33935645 DOI: 10.3389/fnmol.2021.616178  0.31
2021 Casarotto PC, Girych M, Fred SM, Kovaleva V, Moliner R, Enkavi G, Biojone C, Cannarozzo C, Sahu MP, Kaurinkoski K, Brunello CA, Steinzeig A, Winkel F, Patil S, Vestring S, et al. Antidepressant drugs act by directly binding to TRKB neurotrophin receptors. Cell. 184: 1299-1313.e19. PMID 33606976 DOI: 10.1016/j.cell.2021.01.034  0.63
2020 Lesnikova A, Casarotto PC, Fred SM, Voipio M, Winkel F, Steinzeig A, Antila H, Umemori J, Biojone C, Castrén E. Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating control of PTPσ in parvalbumin neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33293360 DOI: 10.1523/JNEUROSCI.2228-20.2020  0.337
2020 Sajanti A, Lyne SB, Girard R, Frantzén J, Rantamäki T, Heino I, Cao Y, Diniz C, Umemori J, Li Y, Takala R, Posti JP, Roine S, Koskimäki F, Rahi M, et al. A comprehensive p75 neurotrophin receptor gene network and pathway analyses identifying new target genes. Scientific Reports. 10: 14984. PMID 32917932 DOI: 10.1038/S41598-020-72061-Z  0.623
2019 Fred SM, Laukkanen L, Brunello CA, Vesa L, Göös H, Cardon I, Moliner R, Maritzen T, Varjosalo M, Casarotto PC, Castrén E. Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2. The Journal of Biological Chemistry. PMID 31631060 DOI: 10.1074/jbc.RA119.008837  0.431
2019 Steinzeig A, Canarozzo C, Castrén E. Fluoxetine-induced plasticity in the visual cortex outlasts the duration of the naturally occurring critical period. The European Journal of Neuroscience. PMID 31299115 DOI: 10.1111/ejn.14512  0.346
2019 Diniz CRAF, Biojone C, Joca SRL, Rantamäki T, Castrén E, Guimarães FS, Casarotto PC. Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors. Peerj. 7: e6493. PMID 30809460 DOI: 10.7717/Peerj.6493  0.661
2019 Fonseca-Gomes J, Jerónimo-Santos A, Lesnikova A, Casarotto P, Castrén E, Sebastião AM, Diógenes MJ. TrkB-ICD Fragment, Originating From BDNF Receptor Cleavage, Is Translocated to Cell Nucleus and Phosphorylates Nuclear and Axonal Proteins. Frontiers in Molecular Neuroscience. 12: 4. PMID 30774582 DOI: 10.3389/Fnmol.2019.00004  0.424
2019 Sahu MP, Pazos-Boubeta Y, Pajanoja C, Rozov S, Panula P, Castrén E. Neurotrophin receptor Ntrk2b function in the maintenance of dopamine and serotonin neurons in zebrafish. Scientific Reports. 9: 2036. PMID 30765816 DOI: 10.1038/s41598-019-39347-3  0.431
2019 Fred SM, Casarotto P, Moliner R, Antila H, Schlüter O, Castrén E. P.1.06 TRKB receptor interaction with postsynaptic density proteins (PSD93 and PSD95) in the mechanism of antidepressants European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.01.009  0.312
2019 Winkel F, Didio G, Llach MP, Steinzeig A, Umemori J, Castrén E. S.14.05 Optical activation of TrkB receptors in Parvalbumin interneurons reopens critical periods in the adult visual cortex European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.11.948  0.301
2019 Casarotto P, Fred SM, Biojone C, Girych M, Rog T, Vattulainen I, Castrén E. Cholesterol-dependent effect of antidepressants on activation BDNF receptor (TRKB) European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.11.493  0.382
2019 Fred SM, Laukkanen L, Vesa L, Lesnikova A, Göös H, Varjosalo M, Rantamäki T, Casarotto PC, Castrén E. Pharmacologically diverse antidepressant drugs disrupt the interaction of neurotrophic factor receptor TRKB and endocytic adaptor protein complex AP-2 European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.11.447  0.642
2018 Carceller H, Perez-Rando M, Castren E, Nacher J, Guirado R. Effects of the Antidepressant Fluoxetine on the Somatostatin Interneurons in the Basolateral Amygdala. Neuroscience. 386: 205-213. PMID 30018016 DOI: 10.1016/J.Neuroscience.2018.06.041  0.388
2018 Umemori J, Winkel F, Didio G, Llach Pou M, Castrén E. iPlasticity: induced juvenile-like plasticity in the adult brain as a mechanism of antidepressants. Psychiatry and Clinical Neurosciences. PMID 29802758 DOI: 10.1111/pcn.12683  0.435
2018 Pryazhnikov E, Mugantseva E, Casarotto P, Kolikova J, Fred SM, Toptunov D, Afzalov R, Hotulainen P, Voikar V, Terry-Lorenzo R, Engel S, Kirov S, Castren E, Khiroug L. Longitudinal two-photon imaging in somatosensory cortex of behaving mice reveals dendritic spine formation enhancement by subchronic administration of low-dose ketamine. Scientific Reports. 8: 6464. PMID 29691465 DOI: 10.1038/S41598-018-24933-8  0.34
2018 Diniz CRAF, Casarotto PC, Fred SM, Biojone C, Castrén E, Joca SRL. Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN. Neuropharmacology. 135: 163-171. PMID 29550391 DOI: 10.1016/j.neuropharm.2018.03.011  0.41
2018 Diniz CRAF, Becari C, Lesnikova A, Biojone C, Salgado MCO, Salgado HC, Resstel LBM, Guimarães FS, Castrén E, Casarotto PC, Joca SRL. Elastase-2 Knockout Mice Display Anxiogenic- and Antidepressant-Like Phenotype: Putative Role for BDNF Metabolism in Prefrontal Cortex. Molecular Neurobiology. PMID 29383685 DOI: 10.1007/S12035-018-0902-6  0.352
2018 Castrén E. Decision letter: BDNF-TrkB signaling in oxytocin neurons contributes to maternal behavior Elife. DOI: 10.7554/Elife.33676.022  0.333
2018 Winkel F, Didio G, Llach MP, Steinzeig A, Umemori J, Castrén E. Optical and pharmacological activation of TrkB receptors in parvalbumin interneurons induces plasticity in the adult visual cortex European Neuropsychopharmacology. 28. DOI: 10.1016/J.Euroneuro.2017.12.031  0.428
2017 Dina P, Castren E, Taira T. Chronic fluoxetine administration enhances synaptic plasticity and increases functional dynamics in hippocampal CA3-CA1 synapses. Neuropharmacology. PMID 28887184 DOI: 10.1016/j.neuropharm.2017.09.003  0.35
2017 Antila H, Ryazantseva M, Popova D, Sipilä P, Guirado R, Kohtala S, Yalcin I, Lindholm J, Vesa L, Sato V, Cordeira J, Autio H, Kislin M, Rios M, Joca S, et al. Isoflurane produces antidepressant effects and induces TrkB signaling in rodents. Scientific Reports. 7: 7811. PMID 28798343 DOI: 10.1038/S41598-017-08166-9  0.77
2017 Mikics É, Guirado R, Umemori J, Tóth M, Biró L, Miskolczi C, Balázsfi D, Zelena D, Castrén E, Haller J, Karpova NN. Social Learning Requires Plasticity Enhanced by Fluoxetine Through Prefrontal Bdnf-TrkB Signaling to Limit Aggression Induced by Post-Weaning Social Isolation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28685757 DOI: 10.1038/Npp.2017.142  0.305
2017 Castrén E, Antila H. Neuronal plasticity and neurotrophic factors in drug responses. Molecular Psychiatry. 22: 1085-1095. PMID 28397840 DOI: 10.1038/mp.2017.61  0.418
2017 Kraus C, Castrén E, Kasper S, Lanzenberger R. Serotonin and Neuroplasticity - Links between molecular, functional and structural pathophysiology in depression. Neuroscience and Biobehavioral Reviews. PMID 28342763 DOI: 10.1016/j.neubiorev.2017.03.007  0.331
2016 Castrén E, Kojima M. Brain-derived neurotrophic factor in mood disorders and antidepressant treatments. Neurobiology of Disease. PMID 27425886 DOI: 10.1016/j.nbd.2016.07.010  0.446
2016 Bertling E, Englund J, Minkeviciene R, Koskinen M, Segerstråle M, Castrén E, Taira T, Hotulainen P. Actin Tyrosine-53-Phosphorylation in Neuronal Maturation and Synaptic Plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 5299-313. PMID 27170127 DOI: 10.1523/Jneurosci.2649-15.2016  0.307
2016 Carceller H, Rovira-Esteban L, Nacher J, Castrén E, Guirado R. Neurochemical Phenotype of Reelin Immunoreactive Cells in the Piriform Cortex Layer II. Frontiers in Cellular Neuroscience. 10: 65. PMID 27013976 DOI: 10.3389/Fncel.2016.00065  0.391
2016 Guirado R, La Terra D, Bourguignon M, Carceller H, Umemori J, Sipilä P, Nacher J, Castrén E. Effects of PSA Removal from NCAM on the Critical Period Plasticity Triggered by the Antidepressant Fluoxetine in the Visual Cortex. Frontiers in Cellular Neuroscience. 10: 22. PMID 26903807 DOI: 10.3389/Fncel.2016.00022  0.381
2016 Casarotto P, Oztas SM, Biojone C, Umemori J, Rantamaki T, Castren E. Antidepressant-induced disruption of TRKB complex European Neuropsychopharmacology. 26. DOI: 10.1016/S0924-977X(16)31110-5  0.615
2015 Guirado R, Umemori J, Sipilä P, Castrén E. Evidence for Competition for Target Innervation in the Medial Prefrontal Cortex. Cerebral Cortex (New York, N.Y. : 1991). PMID 26637448 DOI: 10.1093/cercor/bhv280  0.329
2015 Aonurm-Helm A, Anier K, Zharkovsky T, Castrén E, Rantamäki T, Stepanov V, Järv J, Zharkovsky A. NCAM-deficient mice show prominent abnormalities in serotonergic and BDNF systems in brain - Restoration by chronic amitriptyline. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26499173 DOI: 10.1016/J.Euroneuro.2015.10.001  0.692
2015 Biojone C, Casarotto PC, Joca SR, Castren E. Interplay Between Nitric Oxide and Brain-Derived Neurotrophic Factor in Neuronal Plasticity. Cns & Neurological Disorders Drug Targets. 14: 979-87. PMID 26350341 DOI: 10.2174/1871527314666150909113727  0.368
2015 Song M, Giza J, Proenca CC, Jing D, Elliott M, Dincheva I, Shmelkov SV, Kim J, Schreiner R, Huang SH, Castrén E, Prekeris R, Hempstead BL, Chao MV, Dictenberg JB, et al. Slitrk5 Mediates BDNF-Dependent TrkB Receptor Trafficking and Signaling. Developmental Cell. 33: 690-702. PMID 26004511 DOI: 10.1016/J.Devcel.2015.04.009  0.449
2015 Umemori J, Winkel F, Castrén E, Karpova NN. Distinct effects of perinatal exposure to fluoxetine or methylmercury on parvalbumin and perineuronal nets, the markers of critical periods in brain development. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 44: 55-64. PMID 25997908 DOI: 10.1016/j.ijdevneu.2015.05.006  0.33
2015 Kopra J, Vilenius C, Grealish S, Härma MA, Varendi K, Lindholm J, Castrén E, Võikar V, Björklund A, Piepponen TP, Saarma M, Andressoo JO. GDNF is not required for catecholaminergic neuron survival in vivo. Nature Neuroscience. 18: 319-22. PMID 25710828 DOI: 10.1038/Nn.3941  0.357
2015 Koskimäki J, Matsui N, Umemori J, Rantamäki T, Castrén E. Nimodipine activates TrkB neurotrophin receptors and induces neuroplastic and neuroprotective signaling events in the mouse hippocampus and prefrontal cortex. Cellular and Molecular Neurobiology. 35: 189-96. PMID 25204460 DOI: 10.1007/S10571-014-0110-5  0.686
2014 Karpova NN, Lindholm JS, Kulesskaya N, Onishchenko N, Vahter M, Popova D, Ceccatelli S, Castrén E. TrkB overexpression in mice buffers against memory deficits and depression-like behavior but not all anxiety- and stress-related symptoms induced by developmental exposure to methylmercury. Frontiers in Behavioral Neuroscience. 8: 315. PMID 25309367 DOI: 10.3389/fnbeh.2014.00315  0.373
2014 Jerónimo-Santos A, Vaz SH, Parreira S, Rapaz-Lérias S, Caetano AP, Buée-Scherrer V, Castrén E, Valente CA, Blum D, Sebastião AM, Diógenes MJ. Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain. Cerebral Cortex (New York, N.Y. : 1991). PMID 24860020 DOI: 10.1093/Cercor/Bhu105  0.435
2014 Lindholm JS, Castrén E. Mice with altered BDNF signaling as models for mood disorders and antidepressant effects. Frontiers in Behavioral Neuroscience. 8: 143. PMID 24817844 DOI: 10.3389/fnbeh.2014.00143  0.445
2014 Guirado R, Perez-Rando M, Sanchez-Matarredona D, Castrén E, Nacher J. Chronic fluoxetine treatment alters the structure, connectivity and plasticity of cortical interneurons. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 1635-46. PMID 24786752 DOI: 10.1017/S1461145714000406  0.41
2014 Antila H, Castrén E, Rantamäki T. S.12.06 Antidepressant-like effects of isoflurane anesthesia are mediated by TrkB neurotrophin receptor European Neuropsychopharmacology. 24. DOI: 10.1016/S0924-977X(14)70165-8  0.652
2014 Antila H, Sipilä P, Popova D, Lindholm J, Guirado R, Castrén E, Rantamäki T. P.1.017 Isoflurane anesthesia rapidly activates TrkB receptor signaling and produces antidepressant-like behavioral effects European Neuropsychopharmacology. 24. DOI: 10.1016/S0924-977X(14)70019-7  0.706
2013 Castrén E, Hen R. Neuronal plasticity and antidepressant actions. Trends in Neurosciences. 36: 259-67. PMID 23380665 DOI: 10.1016/j.tins.2012.12.010  0.352
2013 Casarotto P, Guimarães F, Rantamaki T, Castren E. E.10 - DIFFERENTIAL EFFECT OF ANANDAMIDE ON TRKB PHOSPHORYLATION IN CORTICAL AND STRIATAL CELLS Behavioural Pharmacology. 24: e43-e44. DOI: 10.1097/01.Fbp.0000434829.93009.01  0.614
2012 Maya-Vetencourt JF, Baroncelli L, Viegi A, Tiraboschi E, Castren E, Cattaneo A, Maffei L. IGF-1 restores visual cortex plasticity in adult life by reducing local GABA levels. Neural Plasticity. 2012: 250421. PMID 22720172 DOI: 10.1155/2012/250421  0.382
2012 Savelyev SA, Rantamäki T, Rytkönen KM, Castren E, Porkka-Heiskanen T. Sleep homeostasis and depression: studies with the rat clomipramine model of depression. Neuroscience. 212: 149-58. PMID 22516018 DOI: 10.1016/J.Neuroscience.2012.03.029  0.633
2011 Karpova NN, Pickenhagen A, Lindholm J, Tiraboschi E, Kulesskaya N, Agústsdóttir A, Antila H, Popova D, Akamine Y, Bahi A, Sullivan R, Hen R, Drew LJ, Castrén E. Fear erasure in mice requires synergy between antidepressant drugs and extinction training. Science (New York, N.Y.). 334: 1731-4. PMID 22194582 DOI: 10.1126/science.1214592  0.322
2011 Heinrich C, Lähteinen S, Suzuki F, Anne-Marie L, Huber S, Häussler U, Haas C, Larmet Y, Castren E, Depaulis A. Increase in BDNF-mediated TrkB signaling promotes epileptogenesis in a mouse model of mesial temporal lobe epilepsy. Neurobiology of Disease. 42: 35-47. PMID 21220014 DOI: 10.1016/J.Nbd.2011.01.001  0.408
2009 Sallert M, Rantamäki T, Vesikansa A, Anthoni H, Harju K, Yli-Kauhaluoma J, Taira T, Castren E, Lauri SE. Brain-derived neurotrophic factor controls activity-dependent maturation of CA1 synapses by downregulating tonic activation of presynaptic kainate receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11294-303. PMID 19741136 DOI: 10.1523/Jneurosci.0560-09.2009  0.683
2009 O'Leary OF, Wu X, Castren E. Chronic fluoxetine treatment increases expression of synaptic proteins in the hippocampus of the ovariectomized rat: role of BDNF signalling. Psychoneuroendocrinology. 34: 367-81. PMID 18977602 DOI: 10.1016/j.psyneuen.2008.09.015  0.682
2006 Takahashi M, Kakita A, Futamura T, Watanabe Y, Mizuno M, Sakimura K, Castren E, Nabeshima T, Someya T, Nawa H. Sustained brain-derived neurotrophic factor up-regulation and sensorimotor gating abnormality induced by postnatal exposure to phencyclidine: comparison with adult treatment. Journal of Neurochemistry. 99: 770-80. PMID 16903871 DOI: 10.1111/j.1471-4159.2006.04106.x  0.454
2005 Vepsäläinen S, Castren E, Helisalmi S, Iivonen S, Mannermaa A, Lehtovirta M, Hänninen T, Soininen H, Hiltunen M. Genetic analysis of BDNF and TrkB gene polymorphisms in Alzheimer's disease. Journal of Neurology. 252: 423-8. PMID 15726264 DOI: 10.1007/s00415-005-0667-5  0.304
2002 Haapasalo A, Sipola I, Larsson K, Akerman KE, Stoilov P, Stamm S, Wong G, Castren E. Regulation of TRKB surface expression by brain-derived neurotrophic factor and truncated TRKB isoforms. The Journal of Biological Chemistry. 277: 43160-7. PMID 12202482 DOI: 10.1074/Jbc.M205202200  0.42
2002 Stoilov P, Castren E, Stamm S. Analysis of the human TrkB gene genomic organization reveals novel TrkB isoforms, unusual gene length, and splicing mechanism. Biochemical and Biophysical Research Communications. 290: 1054-65. PMID 11798182 DOI: 10.1006/Bbrc.2001.6301  0.324
1999 Kryl D, Yacoubian T, Haapasalo A, Castren E, Lo D, Barker PA. Subcellular localization of full-length and truncated Trk receptor isoforms in polarized neurons and epithelial cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5823-33. PMID 10407023 DOI: 10.1523/Jneurosci.19-14-05823.1999  0.412
1996 Galuske RA, Kim DS, Castren E, Thoenen H, Singer W. Brain-derived neurotrophic factor reversed experience-dependent synaptic modifications in kitten visual cortex. The European Journal of Neuroscience. 8: 1554-9. PMID 8758963 DOI: 10.1111/j.1460-9568.1996.tb01618.x  0.563
1996 Marty S, Carroll P, Cellerino A, Castrén E, Staiger V, Thoenen H, Lindholm D. Brain-derived neurotrophic factor promotes the differentiation of various hippocampal nonpyramidal neurons, including Cajal-Retzius cells, in organotypic slice cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 675-87. PMID 8551351 DOI: 10.1523/Jneurosci.16-02-00675.1996  0.611
1995 Castren E, Thoenen H, Lindholm D. Brain-derived neurotrophic factor messenger RNA is expressed in the septum, hypothalamus and in adrenergic brain stem nuclei of adult rat brain and is increased by osmotic stimulation in the paraventricular nucleus. Neuroscience. 64: 71-80. PMID 7708216 DOI: 10.1016/0306-4522(94)00386-J  0.576
1995 CASTREN E, BERNINGER B, LEINGARTNER A, WANG Z, WAGNER E, LINDHOLM D, THOENEN H. Transcriptional regulation of brain-derived neurotrophic factor mRNA levels in hippocampus by kainic acid is independent of protein synthesis and activation of calmodulin kinase IIa orc-fos Pharmacological Research. 31: 9-9. DOI: 10.1016/1043-6618(95)86296-X  0.706
1994 Lindholm D, Harikka J, da Penha Berzaghi M, Castrén E, Tzimagiorgis G, Hughes RA, Thoenen H. Fibroblast growth factor-5 promotes differentiation of cultured rat septal cholinergic and raphe serotonergic neurons: comparison with the effects of neurotrophins. The European Journal of Neuroscience. 6: 244-52. PMID 8167846 DOI: 10.1111/J.1460-9568.1994.Tb00267.X  0.581
1994 Jung W, Castren E, Odenthal M, Vande Woude GF, Ishii T, Dienes HP, Lindholm D, Schirmacher P. Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain. The Journal of Cell Biology. 126: 485-94. PMID 8034747 DOI: 10.1083/jcb.126.2.485  0.427
1994 Castrén E, Ohga Y, Berzaghi MP, Tzimagiorgis G, Thoenen H, Lindholm D. bcl-2 messenger RNA is localized in neurons of the developing and adult rat brain. Neuroscience. 61: 165-77. PMID 7969891 DOI: 10.1016/0306-4522(94)90069-8  0.494
1994 Lindholm D, Castrén E, Berzaghi M, Blöchl A, Thoenen H. Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain--implications for neuronal plasticity. Journal of Neurobiology. 25: 1362-72. PMID 7852991 DOI: 10.1002/neu.480251105  0.584
1994 Lindholm D, Castrén M, Hengerer B, Leingärtner A, Castrén E, Thoenen H. Glucocorticoids and neurotrophin gene regulation in the nervous system. Annals of the New York Academy of Sciences. 746: 195-202; discussion . PMID 7825876 DOI: 10.1111/J.1749-6632.1994.Tb39234.X  0.482
1994 Lindholm D, da Penha Berzaghi M, Cooper J, Thoenen H, Castrén E. Brain-derived neurotrophic factor and neurotrophin-4 increase neurotrophin-3 expression in the rat hippocampus. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 12: 745-51. PMID 7747601 DOI: 10.1016/0736-5748(94)90054-X  0.623
1993 Castrén E, da Penha Berzaghi M, Lindholm D, Thoenen H. Differential effects of MK-801 on brain-derived neurotrophic factor mRNA levels in different regions of the rat brain. Experimental Neurology. 122: 244-52. PMID 8405262 DOI: 10.1006/exnr.1993.1124  0.606
1993 Castrén E, Pitkänen M, Sirviö J, Parsadanian A, Lindholm D, Thoenen H, Riekkinen PJ. The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus. Neuroreport. 4: 895-8. PMID 8396461 DOI: 10.1097/00001756-199307000-00014  0.596
1993 da Penha Berzaghi M, Cooper J, Castrén E, Zafra F, Sofroniew M, Thoenen H, Lindholm D. Cholinergic regulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) but not neurotrophin-3 (NT-3) mRNA levels in the developing rat hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 3818-26. PMID 8366347 DOI: 10.1523/Jneurosci.13-09-03818.1993  0.601
1993 Lindholm D, Castrén E, Tsoulfas P, Kolbeck R, Berzaghi Mda P, Leingärtner A, Heisenberg CP, Tessarollo L, Parada LF, Thoenen H, Tesarollo L. Neurotrophin-3 induced by tri-iodothyronine in cerebellar granule cells promotes Purkinje cell differentiation. The Journal of Cell Biology. 122: 443-50. PMID 8320266 DOI: 10.1083/Jcb.122.2.443  0.564
1993 Lindholm D, Castrén E, Berzaghi MdP, Thoenen H. Effects of neurotransmitters and hormones on neuronal production of neurotrophins Seminars in Neuroscience. 5: 279-283. DOI: 10.1016/S1044-5765(05)80033-8  0.614
1992 Lindholm D, Castrén E, Hengerer B, Zafra F, Berninger B, Thoenen H. Differential Regulation of Nerve Growth Factor (NGF) Synthesis in Neurons and Astrocytes by Glucocorticoid Hormones. The European Journal of Neuroscience. 4: 404-410. PMID 12106348 DOI: 10.1111/J.1460-9568.1992.Tb00889.X  0.724
1992 Lindholm D, Castrén E, Kiefer R, Zafra F, Thoenen H. Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation. The Journal of Cell Biology. 117: 395-400. PMID 1560032 DOI: 10.1083/Jcb.117.2.395  0.507
1992 Castrén E, Zafra F, Thoenen H, Lindholm D. Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex. Proceedings of the National Academy of Sciences of the United States of America. 89: 9444-8. PMID 1409655 DOI: 10.1073/Pnas.89.20.9444  0.581
1992 Zafra F, Lindholm D, Castrén E, Hartikka J, Thoenen H. Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 4793-9. PMID 1281495 DOI: 10.1523/Jneurosci.12-12-04793.1992  0.603
1991 Panula P, Airaksinen MS, Kivipelto L, Castren E. Kainic acid-induced changes in histamine-immunoreactive nerve fibers in the rat brain. Agents and Actions. 33: 100-3. PMID 1897425 DOI: 10.1007/BF01993138  0.327
1991 Zafra F, Castrén E, Thoenen H, Lindholm D. Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 88: 10037-41. PMID 1658793 DOI: 10.1073/Pnas.88.22.10037  0.593
1989 Laitinen JT, Castren E, Vakkuri O, Saavedra JM. Diurnal rhythm of melatonin binding in the rat suprachiasmatic nucleus. Endocrinology. 124: 1585-7. PMID 2917527 DOI: 10.1210/endo-124-3-1585  0.541
1988 Gutkind JS, Kurihara M, Castren E, Saavedra JM. Increased concentration of angiotensin II binding sites in selected brain areas of spontaneously hypertensive rats. Journal of Hypertension. 6: 79-84. PMID 3351297 DOI: 10.1097/00004872-198801000-00012  0.56
1988 Castren E, Saavedra JM. Repeated stress increases the density of angiotensin II binding sites in rat paraventricular nucleus and subfornical organ. Endocrinology. 122: 370-2. PMID 3335214 DOI: 10.1210/endo-122-1-370  0.549
1987 Shigematsu K, Niwa M, Kurihara M, Castren E, Saavedra JM. Alterations in substance P binding in brain nuclei of spontaneously hypertensive rats. The American Journal of Physiology. 252: H301-6. PMID 2433950 DOI: 10.1152/Ajpheart.1987.252.2.H301  0.569
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