Gunnar Keppler Gouras, Dr. - Publications

2011- Wallenberg Neuroscience Center Lund University, Lund, Skåne län, Sweden 
Alzheimer's disease

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ramakrishna S, Jhaveri V, Konings SC, Nawalpuri B, Chakraborty S, Holst B, Schmid B, Gouras GK, Freude KK, Muddashetty RS. APOE4 affects basal and NMDAR mediated protein synthesis in neurons by perturbing calcium homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34475200 DOI: 10.1523/JNEUROSCI.0435-21.2021  1
2021 Folke J, Arkan S, Martinsson I, Aznar S, Gouras G, Brudek T, Hansen C. DNAJB6b is Downregulated in Synucleinopathies. Journal of Parkinson's Disease. PMID 34334418 DOI: 10.3233/JPD-202512  1
2021 Gustavsson N, Paulus A, Martinsson I, Engdahl A, Medjoubi K, Klementiev K, Somogyi A, Deierborg T, Borondics F, Gouras GK, Klementieva O. Correlative optical photothermal infrared and X-ray fluorescence for chemical imaging of trace elements and relevant molecular structures directly in neurons. Light, Science & Applications. 10: 151. PMID 34294676 DOI: 10.1038/s41377-021-00590-x  1
2021 Roos TT, Garcia MG, Martinsson I, Mabrouk R, Israelsson B, Deierborg T, Kobro-Flatmoen A, Tanila H, Gouras GK. Neuronal spreading and plaque induction of intracellular Aβ and its disruption of Aβ homeostasis. Acta Neuropathologica. PMID 34272583 DOI: 10.1007/s00401-021-02345-9  1
2021 Byman E, Martinsson I, Haukedal H, Gouras G, Freude KK, Wennström M. Neuronal α-amylase is important for neuronal activity and glycogenolysis and reduces in presence of amyloid beta pathology. Aging Cell. e13433. PMID 34261192 DOI: 10.1111/acel.13433  1
2021 Liu D, Guo JJ, Su JH, Svanbergsson A, Yuan L, Haikal C, Li W, Gouras G, Li JY. Differential seeding and propagating efficiency of α-synuclein strains generated in different conditions. Translational Neurodegeneration. 10: 20. PMID 34148543 DOI: 10.1186/s40035-021-00242-5  1
2021 Burrinha T, Martinsson I, Gomes R, Terrasso AP, Gouras GK, Almeida CG. Up-regulation of APP endocytosis by neuronal aging drives amyloid dependent-synapse loss. Journal of Cell Science. PMID 33910234 DOI: 10.1242/jcs.255752  1
2021 Paulus A, Engdahl A, Yang Y, Boza-Serrano A, Bachiller S, Torres-Garcia L, Svanbergsson A, Garcia MG, Gouras GK, Li JY, Deierborg T, Klementieva O. Amyloid Structural Changes Studied by Infrared Microspectroscopy in Bigenic Cellular Models of Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 33810433 DOI: 10.3390/ijms22073430  1
2021 Takahashi RH, Yokotsuka M, Tobiume M, Sato Y, Hasegawa H, Nagao T, Gouras GK. Accumulation of cellular prion protein within β-amyloid oligomer plaques in aged human brains. Brain Pathology (Zurich, Switzerland). e12941. PMID 33624334 DOI: 10.1111/bpa.12941  1
2020 Pomeshchik Y, Klementieva O, Gil J, Martinsson I, Hansen MG, de Vries T, Sancho-Balsells A, Russ K, Savchenko E, Collin A, Vaz AR, Bagnoli S, Nacmias B, Rampon C, Sorbi S, ... ... Gouras GK, et al. Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies. Stem Cell Reports. PMID 32589876 DOI: 10.1016/J.Stemcr.2020.06.001  1
2020 Klementieva O, Sandt C, Martinsson I, Kansiz M, Gouras GK, Borondics F. Super-Resolution Infrared Imaging of Polymorphic Amyloid Aggregates Directly in Neurons. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 1903004. PMID 32195099 DOI: 10.1002/Advs.201903004  1
2019 Gouras GK. Aging, Metabolism, Synaptic Activity, and Aβ in Alzheimer's Disease. Frontiers in Aging Neuroscience. 11: 185. PMID 31396077 DOI: 10.3389/Fnagi.2019.00185  0.01
2019 Martinsson I, Capetillo-Zarate E, Faideau M, Willén K, Esteras N, Frykman S, Tjernberg LO, Gouras GK. APP depletion alters selective pre- and post-synaptic proteins. Molecular and Cellular Neurosciences. PMID 30763689 DOI: 10.1016/J.Mcn.2019.02.003  1
2019 Aso E, Martinsson I, Appelhans D, Effenberg C, Benseny-Cases N, Cladera J, Gouras G, Ferrer I, Klementieva O. Poly(propylene imine) dendrimers with histidine-maltose shell as novel type of nanoparticles for synapse and memory protection. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 30708052 DOI: 10.1016/J.Nano.2019.01.010  1
2018 Wang C, Iashchishyn IA, Pansieri J, Nyström S, Klementieva O, Kara J, Horvath I, Moskalenko R, Rofougaran R, Gouras G, Kovacs GG, Shankar SK, Morozova-Roche LA. S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer's Disease. Scientific Reports. 8: 12836. PMID 30150640 DOI: 10.1038/S41598-018-31141-X  1
2018 Olsson TT, Klementieva O, Gouras GK. Prion-like seeding and nucleation of intracellular amyloid-β. Neurobiology of Disease. 113: 1-10. PMID 29414379 DOI: 10.1016/J.Nbd.2018.01.015  1
2017 Willén K, Sroka A, Takahashi RH, Gouras GK. Heterogeneous Association of Alzheimer's Disease-Linked Amyloid-β and Amyloid-β Protein Precursor with Synapses. Journal of Alzheimer's Disease : Jad. PMID 28869466 DOI: 10.3233/Jad-170262  1
2017 Willén K, Edgar JR, Hasegawa T, Tanaka N, Futter CE, Gouras GK. Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A. Molecular Neurodegeneration. 12: 61. PMID 28835279 DOI: 10.1186/S13024-017-0203-Y  1
2017 Klementieva O, Willén K, Martinsson I, Israelsson B, Engdahl A, Cladera J, Uvdal P, Gouras GK. Pre-plaque conformational changes in Alzheimer's disease-linked Aβ and APP. Nature Communications. 8: 14726. PMID 28287086 DOI: 10.1038/Ncomms14726  1
2017 Takahashi RH, Nagao T, Gouras GK. Plaque formation and the intraneuronal accumulation of β-amyloid in Alzheimer's disease. Pathology International. PMID 28261941 DOI: 10.1111/Pin.12520  1
2016 Beckelman BC, Day S, Zhou X, Donohue M, Gouras GK, Klann E, Keene CD, Ma T. Dysregulation of Elongation Factor 1A Expression is Correlated with Synaptic Plasticity Impairments in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27567813 DOI: 10.3233/Jad-160036  1
2016 Hansson O, Gouras G. Brain activity and Alzheimer's disease: a complex relationship. Brain : a Journal of Neurology. 139: 2109-10. PMID 27457228 DOI: 10.1093/Brain/Aww146  1
2015 Dunning CJ, McGauran G, Willén K, Gouras GK, O'Connell DJ, Linse S. A direct high affinity interaction between Aβ42 and GSK3α stimulates hyperphosphorylation of tau. A new molecular link in Alzheimer's disease? Acs Chemical Neuroscience. PMID 26618561 DOI: 10.1021/Acschemneuro.5B00262  1
2015 Lundgren JL, Ahmed S, Schedin-Weiss S, Gouras GK, Winblad B, Tjernberg LO, Frykman S. ADAM10 and BACE1 are localized to synaptic vesicles. Journal of Neurochemistry. PMID 26296617 DOI: 10.1016/J.Jalz.2015.06.262  1
2015 Edgar JR, Willén K, Gouras GK, Futter CE. ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-β accumulation. Journal of Cell Science. 128: 2520-8. PMID 26002056 DOI: 10.1242/Jcs.170233  1
2015 Gouras GK, Olsson TT, Hansson O. β-Amyloid peptides and amyloid plaques in Alzheimer's disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 3-11. PMID 25371168 DOI: 10.1007/S13311-014-0313-Y  1
2014 Lundgren JL, Ahmed S, Winblad B, Gouras GK, Tjernberg LO, Frykman S. Activity-independent release of the amyloid β-peptide from rat brain nerve terminals. Neuroscience Letters. 566: 125-30. PMID 24602978 DOI: 10.1016/J.Neulet.2014.02.050  1
2014 George S, Rönnbäck A, Gouras GK, Petit GH, Grueninger F, Winblad B, Graff C, Brundin P. Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer's disease. Acta Neuropathologica Communications. 2: 17. PMID 24517102 DOI: 10.1186/2051-5960-2-17  1
2014 Gouras GK, Willén K, Faideau M. The inside-out amyloid hypothesis and synapse pathology in Alzheimer's disease. Neuro-Degenerative Diseases. 13: 142-6. PMID 24080821 DOI: 10.1159/000354776  1
2014 Lundgren JL, Ahmed S, Weiss SS, Winblad B, Gouras GK, Tjernberg LO, Frykman S. Distinct Localization Of Beta- And Gamma-Secretase In Rat Brain Synapses Alzheimers & Dementia. 10: 325. DOI: 10.1016/J.Jalz.2014.05.296  1
2014 Gouras GK. Dementia Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.00159-8  1
2013 Gouras GK. Convergence of synapses, endosomes, and prions in the biology of neurodegenerative diseases. International Journal of Cell Biology. 2013: 141083. PMID 24307901 DOI: 10.1155/2013/141083  1
2013 George S, Petit GH, Gouras GK, Brundin P, Olsson R. Nonsteroidal selective androgen receptor modulators and selective estrogen receptor β agonists moderate cognitive deficits and amyloid-β levels in a mouse model of Alzheimer's disease. Acs Chemical Neuroscience. 4: 1537-48. PMID 24020966 DOI: 10.1021/Cn400133S  1
2013 Takahashi RH, Capetillo-Zarate E, Lin MT, Milner TA, Gouras GK. Accumulation of intraneuronal β-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses. Plos One. 8: e51965. PMID 23372648 DOI: 10.1371/Journal.Pone.0051965  1
2013 Gouras GK. mTOR: at the crossroads of aging, chaperones, and Alzheimer's disease. Journal of Neurochemistry. 124: 747-8. PMID 23278352 DOI: 10.1111/Jnc.12098  1
2012 Knafo S, Gouras GK, Yan XX, Spires-Jones T. Pathology of synapses and dendritic spines. Neural Plasticity. 2012: 972432. PMID 23050169 DOI: 10.1155/2012/972432  1
2012 Gouras GK, Willén K, Tampellini D. Critical role of intraneuronal Aβ in Alzheimer's disease: technical challenges in studying intracellular Aβ. Life Sciences. 91: 1153-8. PMID 22727791 DOI: 10.1016/J.Lfs.2012.06.004  1
2012 Capetillo-Zarate E, Gracia L, Tampellini D, Gouras GK. Intraneuronal Aβ accumulation, amyloid plaques, and synapse pathology in Alzheimer's disease. Neuro-Degenerative Diseases. 10: 56-9. PMID 22269167 DOI: 10.1159/000334762  1
2011 Tampellini D, Rahman N, Lin MT, Capetillo-Zarate E, Gouras GK. Impaired β-amyloid secretion in Alzheimer's disease pathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15384-90. PMID 22031884 DOI: 10.1523/Jneurosci.2986-11.2011  1
2011 Capetillo-Zarate E, Gracia L, Yu F, Banfelder JR, Lin MT, Tampellini D, Gouras GK. High-resolution 3D reconstruction reveals intra-synaptic amyloid fibrils. The American Journal of Pathology. 179: 2551-8. PMID 21925470 DOI: 10.1016/J.Ajpath.2011.07.045  1
2011 Tampellini D, Gouras GK. Analysis of vesicular trafficking in primary neurons by live imaging. Methods in Molecular Biology (Clifton, N.J.). 793: 343-50. PMID 21913111 DOI: 10.1007/978-1-61779-328-8_22  1
2011 Dumont M, Kipiani K, Yu F, Wille E, Katz M, Calingasan NY, Gouras GK, Lin MT, Beal MF. Coenzyme Q10 decreases amyloid pathology and improves behavior in a transgenic mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 27: 211-23. PMID 21799249 DOI: 10.3233/Jad-2011-110209  1
2011 Majumdar A, Capetillo-Zarate E, Cruz D, Gouras GK, Maxfield FR. Degradation of Alzheimer's amyloid fibrils by microglia requires delivery of ClC-7 to lysosomes. Molecular Biology of the Cell. 22: 1664-76. PMID 21441306 DOI: 10.1091/Mbc.E10-09-0745  1
2011 Takahashi RH, Tobiume M, Sato Y, Sata T, Gouras GK, Takahashi H. Accumulation of cellular prion protein within dystrophic neurites of amyloid plaques in the Alzheimer's disease brain. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 31: 208-14. PMID 21062360 DOI: 10.1111/J.1440-1789.2010.01158.X  1
2010 Tampellini D, Capetillo-Zarate E, Dumont M, Huang Z, Yu F, Lin MT, Gouras GK. Effects of synaptic modulation on beta-amyloid, synaptophysin, and memory performance in Alzheimer's disease transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14299-304. PMID 20980585 DOI: 10.1523/Jneurosci.3383-10.2010  1
2010 Ma T, Hoeffer CA, Capetillo-Zarate E, Yu F, Wong H, Lin MT, Tampellini D, Klann E, Blitzer RD, Gouras GK. Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease. Plos One. 5. PMID 20862226 DOI: 10.1371/Journal.Pone.0012845  1
2010 Tampellini D, Gouras GK. Synapses, synaptic activity and intraneuronal abeta in Alzheimer's disease. Frontiers in Aging Neuroscience. 2. PMID 20725518 DOI: 10.3389/Fnagi.2010.00013  1
2010 Gouras GK, Tampellini D, Takahashi RH, Capetillo-Zarate E. Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease. Acta Neuropathologica. 119: 523-41. PMID 20354705 DOI: 10.1007/S00401-010-0679-9  1
2010 Takahashi RH, Capetillo-Zarate E, Lin MT, Milner TA, Gouras GK. Co-occurrence of Alzheimer's disease ß-amyloid and Ï„ pathologies at synapses. Neurobiology of Aging. 31: 1145-52. PMID 18771816 DOI: 10.1016/J.Neurobiolaging.2008.07.021  1
2009 Gouras GK. Immunotherapy for Alzheimer disease. Mabs. 1: 112-4. PMID 20061820 DOI: 10.4161/Mabs.1.2.7829  1
2009 Tampellini D, Rahman N, Gallo EF, Huang Z, Dumont M, Capetillo-Zarate E, Ma T, Zheng R, Lu B, Nanus DM, Lin MT, Gouras GK. Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9704-13. PMID 19657023 DOI: 10.1523/Jneurosci.2292-09.2009  1
2009 Kwan AC, Duff K, Gouras GK, Webb WW. Optical visualization of Alzheimer's pathology via multiphoton-excited intrinsic fluorescence and second harmonic generation. Optics Express. 17: 3679-89. PMID 19259208 DOI: 10.1364/Oe.17.003679  1
2009 Dumont M, Wille E, Calingasan NY, Tampellini D, Williams C, Gouras GK, Liby K, Sporn M, Nathan C, Flint Beal M, Lin MT. Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease. Journal of Neurochemistry. 109: 502-12. PMID 19200343 DOI: 10.1111/J.1471-4159.2009.05970.X  1
2009 Dumont M, Wille E, Calingasan NY, Tampellini D, Williams C, Gouras GK, Liby K, Sporn M, Nathan C, Beal MF, Lin MT. Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease: (Journal of Neurochemistry (2009) 109 (502-512)) Journal of Neurochemistry. 109: 1192. DOI: 10.1111/J.1471-4159.2009.06053.X  1
2007 Venkitaramani DV, Chin J, Netzer WJ, Gouras GK, Lesne S, Malinow R, Lombroso PJ. Beta-amyloid modulation of synaptic transmission and plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11832-7. PMID 17978019 DOI: 10.1523/Jneurosci.3478-07.2007  1
2007 Tampellini D, Magrané J, Takahashi RH, Li F, Lin MT, Almeida CG, Gouras GK. Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations. The Journal of Biological Chemistry. 282: 18895-906. PMID 17468102 DOI: 10.1074/Jbc.M700373200  1
2007 Sahlin C, Lord A, Magnusson K, Englund H, Almeida CG, Greengard P, Nyberg F, Gouras GK, Lannfelt L, Nilsson LN. The Arctic Alzheimer mutation favors intracellular amyloid-beta production by making amyloid precursor protein less available to alpha-secretase. Journal of Neurochemistry. 101: 854-62. PMID 17448150 DOI: 10.1111/J.1471-4159.2006.04443.X  1
2007 Gouras GK. Alzheimer's disease therapy: Focus on synapses Future Neurology. 2: 469-470. DOI: 10.2217/14796708.2.5.469  1
2006 Almeida CG, Takahashi RH, Gouras GK. Beta-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4277-88. PMID 16624948 DOI: 10.1523/Jneurosci.5078-05.2006  1
2006 Gouras G, Fillit H. Neurogenesis as a therapeutic strategy for cognitive aging and Alzheimer's disease. Current Alzheimer Research. 3: 3. PMID 16472195 DOI: 10.2174/156720506775697151  1
2006 Stenh C, Lord A, Magnusson K, Englund H, Almeida CG, Greengard P, Nyberg F, Gouras GK, Lannfelt L, Nilsson LNG. AbstractPoster presentation: Wednesday posterP4-041: The Arctic Alzheimer mutation favors Aβ production by making APP less available to α-secretase at the cell surface Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1779  1
2005 Magrané J, Rosen KM, Smith RC, Walsh K, Gouras GK, Querfurth HW. Intraneuronal beta-amyloid expression downregulates the Akt survival pathway and blunts the stress response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10960-9. PMID 16306409 DOI: 10.1523/Jneurosci.1723-05.2005  1
2005 Almeida CG, Tampellini D, Takahashi RH, Greengard P, Lin MT, Snyder EM, Gouras GK. Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses. Neurobiology of Disease. 20: 187-98. PMID 16242627 DOI: 10.1016/J.Nbd.2005.02.008  1
2005 Saura CA, Chen G, Malkani S, Choi SY, Takahashi RH, Zhang D, Gouras GK, Kirkwood A, Morris RG, Shen J. Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6755-64. PMID 16033885 DOI: 10.1523/Jneurosci.1247-05.2005  1
2005 Snyder EM, Nong Y, Almeida CG, Paul S, Moran T, Choi EY, Nairn AC, Salter MW, Lombroso PJ, Gouras GK, Greengard P. Regulation of NMDA receptor trafficking by amyloid-beta. Nature Neuroscience. 8: 1051-8. PMID 16025111 DOI: 10.1038/Nn1503  1
2005 Gouras GK, Almeida CG, Takahashi RH. Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease. Neurobiology of Aging. 26: 1235-44. PMID 16023263 DOI: 10.1016/J.Neurobiolaging.2005.05.022  1
2005 Stenh C, Englund H, Lord A, Johansson AS, Almeida CG, Gellerfors P, Greengard P, Gouras GK, Lannfelt L, Nilsson LN. Amyloid-beta oligomers are inefficiently measured by enzyme-linked immunosorbent assay. Annals of Neurology. 58: 147-50. PMID 15984012 DOI: 10.1002/Ana.20524  1
2005 Weksler ME, Gouras G, Relkin NR, Szabo P. The immune system, amyloid-beta peptide, and Alzheimer's disease. Immunological Reviews. 205: 244-56. PMID 15882358 DOI: 10.1111/J.0105-2896.2005.00264.X  1
2004 Busciglio J, Brady S, Takashima A, Klein P, Kim L, LaFerla F, Geula C, Stokely M, Tezapsidis N, Gouras G, Strobel G, Crutcher K, Forero D. Axonal transport hypothesis moves on to implicate presenilin: Alzheimer research forum live discussion Journal of Alzheimer's Disease. 6: 537-545. PMID 15573458 DOI: 10.3233/Jad-2004-6511  1
2004 Li F, Calingasan NY, Yu F, Mauck WM, Toidze M, Almeida CG, Takahashi RH, Carlson GA, Flint Beal M, Lin MT, Gouras GK. Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice. Journal of Neurochemistry. 89: 1308-12. PMID 15147524 DOI: 10.1111/J.1471-4159.2004.02455.X  1
2004 Takahashi RH, Almeida CG, Kearney PF, Yu F, Lin MT, Milner TA, Gouras GK. Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3592-9. PMID 15071107 DOI: 10.1523/Jneurosci.5167-03.2004  1
2004 Gouras G, LaFerla F, Strobel G, Busciglio J, Almeida C, Geula C, Stenh C, Lee D, D'Andrea M, Nagele B, Takahashi R, Hartmann T, LeBlanc A, Dineley K, Koudinov A. Intraneuronal Aβ accumulation-more evidence, less controversy? Alzheimer research forum live discussion Journal of Alzheimer's Disease. 6: 443-449. DOI: 10.3233/Jad-2004-6413  1
2003 Goldstein L, Ashford JW, Busciglio J, Crutcher K, Gouras G, Kinoshita J, Mandelkow E, Sudol M. Live discussion. From here to there: AbetaPP as an axonal transport receptor--how could this explain neurodegeneration in AD. 15 July 2002. Journal of Alzheimer's Disease : Jad. 5: 483-9. PMID 14765517  1
2003 Dou F, Netzer WJ, Tanemura K, Li F, Hartl FU, Takashima A, Gouras GK, Greengard P, Xu H. Chaperones increase association of tau protein with microtubules. Proceedings of the National Academy of Sciences of the United States of America. 100: 721-6. PMID 12522269 DOI: 10.1073/Pnas.242720499  1
2002 Takahashi RH, Milner TA, Li F, Nam EE, Edgar MA, Yamaguchi H, Beal MF, Xu H, Greengard P, Gouras GK. Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology. The American Journal of Pathology. 161: 1869-79. PMID 12414533 DOI: 10.1016/S0002-9440(10)64463-X  1
2002 Takahashi RH, Nam EE, Edgar M, Gouras GK. Alzheimer beta-amyloid peptides: normal and abnormal localization. Histology and Histopathology. 17: 239-46. PMID 11813874 DOI: 10.14670/Hh-17.239  1
2001 Gouras GK. Current theories for the molecular and cellular pathogenesis of Alzheimers disease. Expert Reviews in Molecular Medicine. 2001: 1-11. PMID 14987364 DOI: 10.1017/S1462399401003167  0.01
2001 Gouras GK, Beal MF. Metal chelator decreases Alzheimer beta-amyloid plaques. Neuron. 30: 641-2. PMID 11430794 DOI: 10.1016/S0896-6273(01)00330-0  1
2001 Gasparini L, Gouras GK, Wang R, Gross RS, Beal MF, Greengard P, Xu H. Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 2561-70. PMID 11306609  1
2000 Greenfield JP, Gross RS, Gouras GK, Xu H. Cellular and molecular basis of beta-amyloid precursor protein metabolism. Frontiers in Bioscience : a Journal and Virtual Library. 5: D72-83. PMID 10702374  1
2000 Gouras GK, Xu H, Gross RS, Greenfield JP, Hai B, Wang R, Greengard P. Testosterone reduces neuronal secretion of Alzheimer's beta-amyloid peptides. Proceedings of the National Academy of Sciences of the United States of America. 97: 1202-5. PMID 10655508 DOI: 10.1073/Pnas.97.3.1202  1
2000 Gouras GK, Tsai J, Naslund J, Vincent B, Edgar M, Checler F, Greenfield JP, Haroutunian V, Buxbaum JD, Xu H, Greengard P, Relkin NR. Intraneuronal Abeta42 accumulation in human brain. The American Journal of Pathology. 156: 15-20. PMID 10623648 DOI: 10.1016/S0002-9440(10)64700-1  1
1999 Greenfield JP, Tsai J, Gouras GK, Hai B, Thinakaran G, Checler F, Sisodia SS, Greengard P, Xu H. Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides. Proceedings of the National Academy of Sciences of the United States of America. 96: 742-7. PMID 9892704 DOI: 10.1073/Pnas.96.2.742  1
1998 Gouras GK, Xu H, Jovanovic JN, Buxbaum JD, Wang R, Greengard P, Relkin NR, Gandy S. Generation and regulation of beta-amyloid peptide variants by neurons. Journal of Neurochemistry. 71: 1920-5. PMID 9798916 DOI: 10.1046/J.1471-4159.1998.71051920.X  1
1998 Xu H, Gouras GK, Greenfield JP, Vincent B, Naslund J, Mazzarelli L, Fried G, Jovanovic JN, Seeger M, Relkin NR, Liao F, Checler F, Buxbaum JD, Chait BT, Thinakaran G, et al. Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides. Nature Medicine. 4: 447-51. PMID 9546791 DOI: 10.1038/Nm0498-447  1
1998 Greenfield JP, Gouras GK, Xu H. Cellular and molecular basis of beta-amyloid precursor protein metabolism. Frontiers in Bioscience : a Journal and Virtual Library. 3: d399-407. PMID 9514984  1
1997 Seeger M, Nordstedt C, Petanceska S, Kovacs DM, Gouras GK, Hahne S, Fraser P, Levesque L, Czernik AJ, George-Hyslop PS, Sisodia SS, Thinakaran G, Tanzi RE, Greengard P, Gandy S. Evidence for phosphorylation and oligomeric assembly of presenilin 1. Proceedings of the National Academy of Sciences of the United States of America. 94: 5090-4. PMID 9144195 DOI: 10.1073/Pnas.94.10.5090  1
1997 Gouras GK, Relkin NR, Sweeney D, Munoz DG, Mackenzie IR, Gandy S. Increased apolipoprotein E epsilon 4 in epilepsy with senile plaques. Annals of Neurology. 41: 402-4. PMID 9066363 DOI: 10.1002/Ana.410410317  1
1996 Kaplitt M, Gouras GK, Makimura H, Jovanovic J, Sweeney D, Greengard P, Relkin NR, Gandy S. Apolipoprotein E, A beta-amyloid, and the molecular pathology of Alzheimer's disease. Therapeutic implications. Annals of the New York Academy of Sciences. 802: 42-9. PMID 8993483 DOI: 10.1111/J.1749-6632.1996.Tb32597.X  1
1996 Rutkove SB, De Girolami U, Preston DC, Freeman R, Nardin RA, Gouras GK, Johns DR, Raynor EM. Myotonia in colchicine myoneuropathy. Muscle & Nerve. 19: 870-5. PMID 8965841 DOI: 10.1002/(Sici)1097-4598(199607)19:7<870::Aid-Mus9>3.0.Co;2-6  1
1996 Relkin NR, Edgar MA, Gouras GK, Gandy SE, Goldsmith HS. Decreased senile plaque density in Alzheimer neocortex adjacent to an omental transposition. Neurological Research. 18: 291-4; discussion 29. PMID 8875444 DOI: 10.1080/01616412.1996.11740423  1
1996 Lagreze WD, Warner JE, Zamani AA, Gouras GK, Koralnik IJ, Bienfang DC. Mesencephalic clefts with associated eye movement disorders. Archives of Ophthalmology (Chicago, Ill. : 1960). 114: 429-32. PMID 8602780 DOI: 10.1001/Archopht.1996.01100130425012  1
1994 Koliatsos VE, Price DL, Gouras GK, Cayouette MH, Burton LE, Winslow JW. Highly selective effects of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 on intact and injured basal forebrain magnocellular neurons. The Journal of Comparative Neurology. 343: 247-62. PMID 8027442 DOI: 10.1002/Cne.903430206  1
1992 Gouras GK, Rance NE, Young WS, Koliatsos VE. Tyrosine-hydroxylase-containing neurons in the primate basal forebrain magnocellular complex. Brain Research. 584: 287-93. PMID 1355392 DOI: 10.1016/0006-8993(92)90907-Q  1
1991 Koliatsos VE, Clatterbuck RE, Gouras GK, Price DL. Biologic effects of nerve growth factor on lesioned basal forebrain neurons. Annals of the New York Academy of Sciences. 640: 102-9. PMID 1776727 DOI: 10.1111/J.1749-6632.1991.Tb00199.X  1
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