| Year |
Citation |
Score |
| 2024 |
Yin T, Yesiltepe M, D'Adamio L. Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias. Embo Reports. PMID 38347225 DOI: 10.1038/s44319-024-00077-x |
0.433 |
|
| 2023 |
D'Adamio L. Transfixed by transgenics: how pathology assumptions are slowing progress in Alzheimer's disease and related dementia research. Embo Molecular Medicine. 15: e18479. PMID 37750482 DOI: 10.15252/emmm.202318479 |
0.312 |
|
| 2023 |
Yesiltepe M, Yin T, D'Adamio L. Beyond amyloid: altered gene function in neurodegenerative diseases. Aging. 15: 9235-9237. PMID 37733660 DOI: 10.18632/aging.204717 |
0.8 |
|
| 2023 |
Yin T, D'Adamio L. BRI2-mediated regulation of TREM2 processing in microglia and its potential implications for Alzheimer's disease and related dementias. Biorxiv : the Preprint Server For Biology. PMID 37398330 DOI: 10.1101/2023.06.14.544924 |
0.444 |
|
| 2023 |
Puliatti G, Li Puma DD, Aceto G, Lazzarino G, Acquarone E, Mangione R, D'Adamio L, Ripoli C, Arancio O, Piacentini R, Grassi C. Intracellular accumulation of tau oligomers in astrocytes and their synaptotoxic action rely on Amyloid Precursor Protein Intracellular Domain-dependent expression of Glypican-4. Progress in Neurobiology. 227: 102482. PMID 37321444 DOI: 10.1016/j.pneurobio.2023.102482 |
0.316 |
|
| 2023 |
Tambini MD, Yin T, Yesiltepe M, Breuillaud L, Zehntner SP, d'Abramo C, Giliberto L, D'Adamio L. Aβ43 levels determine the onset of pathological amyloid deposition. The Journal of Biological Chemistry. 104868. PMID 37257821 DOI: 10.1016/j.jbc.2023.104868 |
0.829 |
|
| 2022 |
Yesiltepe M, Yin T, Tambini MD, Breuillaud L, Zehntner SP, D'Adamio L. Late-long-term potentiation magnitude, but not Aβ levels and amyloid pathology, is associated with behavioral performance in a rat knock-in model of Alzheimer disease. Frontiers in Aging Neuroscience. 14: 1040576. PMID 36438008 DOI: 10.3389/fnagi.2022.1040576 |
0.802 |
|
| 2022 |
Pham H, Yin T, D'Adamio L. Initial assessment of the spatial learning, reversal, and sequencing task capabilities of knock-in rats with humanizing mutations in the Aβ-coding region of App. Plos One. 17: e0263546. PMID 35507596 DOI: 10.1371/journal.pone.0263546 |
0.654 |
|
| 2021 |
Yin T, Yao W, Norris KA, D'Adamio L. A Familial Danish dementia rat shows impaired pre- and postsynaptic glutamatergic transmission. The Journal of Biological Chemistry. 101089. PMID 34416235 DOI: 10.1016/j.jbc.2021.101089 |
0.714 |
|
| 2020 |
Tambini MD, D'Adamio L. Knock-in rats with homozygous PSEN1 Alzheimer mutation are viable and show selective γ-secretase activity loss causing low Aβ40/42 and high Aβ43. The Journal of Biological Chemistry. 295: 7442-7451. PMID 33516363 DOI: 10.1074/jbc.RA120.012542 |
0.438 |
|
| 2020 |
Ren S, Breuillaud L, Yao W, Yin T, Norris KA, Zehntner SP, D'Adamio L. TNF-α-mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimer's disease pathology in young Trem2 rats. The Journal of Biological Chemistry. 296: 100089. PMID 33434745 DOI: 10.1074/jbc.RA120.016395 |
0.695 |
|
| 2020 |
Ren S, Breuillaud L, Yao W, Yin T, Norris KA, Zehntner SP, D'Adamio L. TNF-α-mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimer's disease pathology in young rats. The Journal of Biological Chemistry. PMID 33199501 DOI: 10.1074/jbc.RA120.016395 |
0.402 |
|
| 2020 |
Yin T, Yao W, Lemenze AD, D'Adamio L. Danish and British dementia mutations reduce BRI2 protein stability and impair glutamatergic synaptic transmission. The Journal of Biological Chemistry. PMID 33172889 DOI: 10.1074/jbc.RA120.015679 |
0.655 |
|
| 2020 |
d'Abramo C, D'Adamio L, Giliberto L. Significance of Blood and Cerebrospinal Fluid Biomarkers for Alzheimer's Disease: Sensitivity, Specificity and Potential for Clinical Use. Journal of Personalized Medicine. 10. PMID 32911755 DOI: 10.3390/jpm10030116 |
0.37 |
|
| 2020 |
Ren S, Yao W, Tambini MD, Yin T, Norris KA, D'Adamio L. Microglia Alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels. Elife. 9. PMID 32579116 DOI: 10.7554/Elife.57513 |
0.673 |
|
| 2020 |
Puzzo D, Argyrousi EK, Staniszewski A, Zhang H, Calcagno E, Zuccarello E, Acquarone E, Fà M, Li Puma DD, Grassi C, D'Adamio L, Kanaan NM, Fraser PE, Arancio O. Tau is not necessary for amyloid-beta-induced synaptic and memory impairments. The Journal of Clinical Investigation. PMID 32544084 DOI: 10.1172/Jci137040 |
0.534 |
|
| 2020 |
Tambini MD, D'Adamio L. Knock-in rats with homozygous Alzheimer mutation are viable and show selective γ-secretase activity loss causing low Aβ40/42, high Aβ43. The Journal of Biological Chemistry. PMID 32265300 DOI: 10.1074/Jbc.Ra120.012542 |
0.516 |
|
| 2020 |
Tambini MD, D'Adamio L. Trem2 Splicing and Expression are Preserved in a Human Aβ-producing, Rat Knock-in Model of Trem2-R47H Alzheimer's Risk Variant. Scientific Reports. 10: 4122. PMID 32139718 DOI: 10.1038/s41598-020-60800-1 |
0.362 |
|
| 2020 |
Tambini MD, Norris KA, D'Adamio L. Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation. Elife. 9. PMID 32022689 DOI: 10.7554/Elife.52612 |
0.507 |
|
| 2020 |
Ren S, Yao W, Tambini MD, Yin T, Norris KA, D'Adamio L. Author response: Microglia TREM2R47H Alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels Elife. DOI: 10.7554/Elife.57513.Sa2 |
0.338 |
|
| 2020 |
Tambini MD, Norris KA, D'Adamio L. Author response: Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation Elife. DOI: 10.7554/Elife.52612.Sa2 |
0.419 |
|
| 2019 |
Tambini MD, Yao W, D'Adamio L. Facilitation of glutamate, but not GABA, release in Familial Alzheimer's APP mutant Knock-in rats with increased β-cleavage of APP. Aging Cell. e13033. PMID 31496118 DOI: 10.1111/Acel.13033 |
0.497 |
|
| 2019 |
Acquarone E, Argyrousi EK, van den Berg M, Gulisano W, Fà M, Staniszewski A, Calcagno E, Zuccarello E, D'Adamio L, Deng SX, Puzzo D, Arancio O, Fiorito J. Synaptic and memory dysfunction induced by tau oligomers is rescued by up-regulation of the nitric oxide cascade. Molecular Neurodegeneration. 14: 26. PMID 31248451 DOI: 10.1186/S13024-019-0326-4 |
0.418 |
|
| 2019 |
Yao W, Tambini MD, Liu X, D'Adamio L. Tuning of glutamate, but not GABA, release by an intra-synaptic vesicles APP domain whose function can be modulated by β- or α-secretase cleavage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31235642 DOI: 10.1523/Jneurosci.0207-19.2019 |
0.434 |
|
| 2019 |
Yao W, Yin T, Tambini MD, D'Adamio L. The Familial dementia gene ITM2b/BRI2 facilitates glutamate transmission via both presynaptic and postsynaptic mechanisms. Scientific Reports. 9: 4862. PMID 30890756 DOI: 10.1038/s41598-019-41340-9 |
0.612 |
|
| 2019 |
Gulisano W, Maugeri D, Baltrons MA, Fà M, Amato A, Palmeri A, D'Adamio L, Grassi C, Devanand DP, Honig LS, Puzzo D, Arancio O. Role of Amyloid-β and Tau Proteins in Alzheimer's Disease: Confuting the Amyloid Cascade. Journal of Alzheimer's Disease : Jad. 68: 415. PMID 30883364 DOI: 10.3233/JAD-189015 |
0.43 |
|
| 2018 |
Gulisano W, Maugeri D, Baltrons MA, Fà M, Amato A, Palmeri A, D'Adamio L, Grassi C, Devanand DP, Honig LS, Puzzo D, Arancio O. Role of Amyloid-β and Tau Proteins in Alzheimer's Disease: Confuting the Amyloid Cascade. Journal of Alzheimer's Disease : Jad. PMID 29865055 DOI: 10.3233/Jad-179935 |
0.464 |
|
| 2018 |
Bavley CC, Rice RC, Fischer DK, Fakira AK, Byrne M, Kosovsky M, Rizzo BK, Del Prete D, Alaedini A, Morón JA, Higgins JJ, D'Adamio L, Rajadhyaksha AM. Rescue of learning and memory deficits in the human non-syndromic intellectual disability cereblon knockout mouse model by targeting the AMPK-mTORC1 translational pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29459374 DOI: 10.1523/Jneurosci.0599-17.2018 |
0.367 |
|
| 2018 |
Biundo F, Del Prete D, Zhang H, Arancio O, D'Adamio L. A role for tau in learning, memory and synaptic plasticity. Scientific Reports. 8: 3184. PMID 29453339 DOI: 10.1038/S41598-018-21596-3 |
0.473 |
|
| 2017 |
Biundo F, d'Abramo C, Tambini MD, Zhang H, Del Prete D, Vitale F, Giliberto L, Arancio O, D'Adamio L. Abolishing Tau cleavage by caspases at Aspartate(421) causes memory/synaptic plasticity deficits and pre-pathological Tau alterations. Translational Psychiatry. 7: e1198. PMID 28786980 DOI: 10.1038/Tp.2017.165 |
0.499 |
|
| 2017 |
Puzzo D, Piacentini R, Fa' M, Gulisano W, Li Puma DD, Staniszewski A, Zhang H, Tropea MR, Cocco S, Palmeri A, Fraser P, D'Adamio L, Grassi C, Arancio O. LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent. Elife. 6. PMID 28696204 DOI: 10.7554/Elife.26991 |
0.521 |
|
| 2017 |
Puzzo D, Piacentini R, Fá M, Gulisano W, Puma DDL, Staniszewski A, Zhang H, Tropea MR, Cocco S, Palmeri A, Fraser P, D'Adamio L, Grassi C, Arancio O. Author response: LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent Elife. DOI: 10.7554/Elife.26991.025 |
0.451 |
|
| 2016 |
Del Prete D, Rice RC, Rajadhyaksha AM, D'Adamio L. APP may act as a substrate and a recognition unit for CRL4CRBN and Stub1 E3 ligases facilitating ubiquitination of proteins involved in presynaptic functions and neurodegeneration. The Journal of Biological Chemistry. PMID 27325702 DOI: 10.1074/Jbc.M116.733626 |
0.476 |
|
| 2016 |
Biundo F, Ishiwari K, Del Prete D, D'Adamio L. Deletion of the γ-secretase subunits Aph1B/C impairs memory and worsens the deficits of knock-in mice modeling the Alzheimer-like familial Danish dementia. Oncotarget. PMID 26942869 DOI: 10.18632/Oncotarget.7389 |
0.432 |
|
| 2016 |
Fá M, Puzzo D, Piacentini R, Staniszewski A, Zhang H, Baltrons MA, Li Puma DD, Chatterjee I, Li J, Saeed F, Berman HL, Ripoli C, Gulisano W, Gonzalez J, Tian H, et al. Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory. Scientific Reports. 6: 19393. PMID 26786552 DOI: 10.1038/Srep19393 |
0.411 |
|
| 2015 |
Fanutza T, Del Prete D, Ford MJ, Castillo PE, D'Adamio L. APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses. Elife. 4. PMID 26551565 DOI: 10.7554/eLife.09743 |
0.379 |
|
| 2015 |
Biundo F, Ishiwari K, Del Prete D, D'Adamio L. Interaction of ApoE3 and ApoE4 isoforms with an ITM2b/BRI2 mutation linked to the Alzheimer disease-like Danish dementia: Effects on learning and memory. Neurobiology of Learning and Memory. 126: 18-30. PMID 26528887 DOI: 10.1016/J.Nlm.2015.10.009 |
0.363 |
|
| 2015 |
Li M, Pehar M, Liu Y, Bhattacharyya A, Zhang SC, O'Riordan KJ, Burger C, D'Adamio L, Puglielli L. The amyloid precursor protein (APP) intracellular domain regulates translation of p44, a short isoform of p53, through an IRES-dependent mechanism. Neurobiology of Aging. PMID 26174856 DOI: 10.1016/J.Neurobiolaging.2015.06.021 |
0.401 |
|
| 2014 |
Del Prete D, Lombino F, Liu X, D'Adamio L. APP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functions. Plos One. 9: e108576. PMID 25247712 DOI: 10.1371/Journal.Pone.0108576 |
0.408 |
|
| 2013 |
Lombino F, Biundo F, Tamayev R, Arancio O, D'Adamio L. An intracellular threonine of amyloid-β precursor protein mediates synaptic plasticity deficits and memory loss. Plos One. 8: e57120. PMID 23451158 DOI: 10.1371/Journal.Pone.0057120 |
0.816 |
|
| 2012 |
Tamayev R, Akpan N, Arancio O, Troy CM, D'Adamio L. Caspase-9 mediates synaptic plasticity and memory deficits of Danish dementia knock-in mice: caspase-9 inhibition provides therapeutic protection. Molecular Neurodegeneration. 7: 60. PMID 23217200 DOI: 10.1186/1750-1326-7-60 |
0.792 |
|
| 2012 |
Matrone C, Luvisetto S, La Rosa LR, Tamayev R, Pignataro A, Canu N, Yang L, Barbagallo AP, Biundo F, Lombino F, Zheng H, Ammassari-Teule M, D'Adamio L. Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance. Aging Cell. 11: 1084-93. PMID 23020178 DOI: 10.1111/Acel.12009 |
0.806 |
|
| 2012 |
Vitale M, Renzone G, Matsuda S, Scaloni A, D'Adamio L, Zambrano N. Proteomic characterization of a mouse model of familial Danish dementia. Journal of Biomedicine & Biotechnology. 2012: 728178. PMID 22619496 DOI: 10.1155/2012/728178 |
0.437 |
|
| 2012 |
Tamayev R, D'Adamio L. Inhibition of γ-secretase worsens memory deficits in a genetically congruous mouse model of Danish dementia. Molecular Neurodegeneration. 7: 19. PMID 22537414 DOI: 10.1186/1750-1326-7-19 |
0.796 |
|
| 2012 |
Tamayev R, D'Adamio L. Memory deficits of British dementia knock-in mice are prevented by Aβ-precursor protein haploinsufficiency. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5481-5. PMID 22514310 DOI: 10.1523/Jneurosci.5193-11.2012 |
0.79 |
|
| 2012 |
Tamayev R, Matsuda S, Arancio O, D'Adamio L. β- but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia. Embo Molecular Medicine. 4: 171-9. PMID 22170863 DOI: 10.1002/Emmm.201100195 |
0.808 |
|
| 2011 |
Matrone C, Barbagallo AP, La Rosa LR, Florenzano F, Ciotti MT, Mercanti D, Chao MV, Calissano P, D'Adamio L. APP is phosphorylated by TrkA and regulates NGF/TrkA signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11756-61. PMID 21849536 DOI: 10.1523/Jneurosci.1960-11.2011 |
0.528 |
|
| 2011 |
Matsuda S, Tamayev R, D'Adamio L. Increased AβPP processing in familial Danish dementia patients. Journal of Alzheimer's Disease : Jad. 27: 385-91. PMID 21841249 DOI: 10.3233/Jad-2011-110785 |
0.803 |
|
| 2011 |
Tamayev R, Matsuda S, Giliberto L, Arancio O, D'Adamio L. APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant. The Embo Journal. 30: 2501-9. PMID 21587206 DOI: 10.1038/Emboj.2011.161 |
0.817 |
|
| 2011 |
Barbagallo AP, Wang Z, Zheng H, D'Adamio L. The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function. Plos One. 6: e18006. PMID 21445342 DOI: 10.1371/Journal.Pone.0018006 |
0.524 |
|
| 2011 |
Barbagallo AP, Wang Z, Zheng H, D'Adamio L. A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function. The Journal of Biological Chemistry. 286: 8717-21. PMID 21266574 DOI: 10.1074/Jbc.C111.219873 |
0.487 |
|
| 2011 |
Matsuda S, Matsuda Y, Snapp EL, D'Adamio L. Maturation of BRI2 generates a specific inhibitor that reduces APP processing at the plasma membrane and in endocytic vesicles. Neurobiology of Aging. 32: 1400-8. PMID 19748705 DOI: 10.1016/J.Neurobiolaging.2009.08.005 |
0.389 |
|
| 2010 |
Barbagallo AP, Weldon R, Tamayev R, Zhou D, Giliberto L, Foreman O, D'Adamio L. Tyr(682) in the intracellular domain of APP regulates amyloidogenic APP processing in vivo. Plos One. 5: e15503. PMID 21103325 DOI: 10.1371/Journal.Pone.0015503 |
0.84 |
|
| 2010 |
Tamayev R, Matsuda S, FÃ M, Arancio O, D'Adamio L. Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits. Proceedings of the National Academy of Sciences of the United States of America. 107: 20822-7. PMID 21098268 DOI: 10.1073/Pnas.1011689107 |
0.783 |
|
| 2010 |
Tamayev R, Giliberto L, Li W, d'Abramo C, Arancio O, Vidal R, D'Adamio L. Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14915-24. PMID 21048150 DOI: 10.1523/Jneurosci.3917-10.2010 |
0.786 |
|
| 2010 |
Giliberto L, d'Abramo C, Acker CM, Davies P, D'Adamio L. Transgenic expression of the amyloid-beta precursor protein-intracellular domain does not induce Alzheimer's Disease-like traits in vivo. Plos One. 5: e11609. PMID 20661273 DOI: 10.1371/Journal.Pone.0011609 |
0.555 |
|
| 2010 |
Garringer HJ, Murrell J, D'Adamio L, Ghetti B, Vidal R. Modeling familial British and Danish dementia. Brain Structure & Function. 214: 235-44. PMID 19779737 DOI: 10.1007/S00429-009-0221-9 |
0.486 |
|
| 2010 |
Tamayev R, Matsuda S, Fa' M, Arancio O, D'Adamio L. O4-05-04: Do BRI2 mutations cause early onset Alzheimer's disease? Alzheimer's & Dementia. 6: S157-S158. DOI: 10.1016/J.Jalz.2010.05.491 |
0.758 |
|
| 2009 |
Giliberto L, Matsuda S, Vidal R, D'Adamio L. Generation and initial characterization of FDD knock in mice. Plos One. 4: e7900. PMID 19924302 DOI: 10.1371/Journal.Pone.0007900 |
0.554 |
|
| 2009 |
Matsuda S, Matsuda Y, D'Adamio L. CD74 interacts with APP and suppresses the production of Abeta. Molecular Neurodegeneration. 4: 41. PMID 19849849 DOI: 10.1186/1750-1326-4-41 |
0.521 |
|
| 2009 |
Tamayev R, Zhou D, D'Adamio L. The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains. Molecular Neurodegeneration. 4: 28. PMID 19602287 DOI: 10.1186/1750-1326-4-28 |
0.825 |
|
| 2009 |
Matsuda S, Matsuda Y, D'Adamio L. BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2. The Journal of Biological Chemistry. 284: 15815-25. PMID 19366692 DOI: 10.1074/Jbc.M109.006403 |
0.548 |
|
| 2009 |
Zhou D, Zambrano N, Russo T, D'Adamio L. Phosphorylation of a tyrosine in the amyloid-beta protein precursor intracellular domain inhibits Fe65 binding and signaling. Journal of Alzheimer's Disease : Jad. 16: 301-7. PMID 19221419 DOI: 10.3233/Jad-2009-0970 |
0.624 |
|
| 2008 |
Giliberto L, Zhou D, Weldon R, Tamagno E, De Luca P, Tabaton M, D'Adamio L. Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role. Molecular Neurodegeneration. 3: 12. PMID 18764939 DOI: 10.1186/1750-1326-3-12 |
0.648 |
|
| 2008 |
Matsuda S, Giliberto L, Matsuda Y, McGowan EM, D'Adamio L. BRI2 inhibits amyloid beta-peptide precursor protein processing by interfering with the docking of secretases to the substrate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8668-76. PMID 18753367 DOI: 10.1523/Jneurosci.2094-08.2008 |
0.583 |
|
| 2007 |
Visconti R, D'Adamio L. Functional cloning of genes regulating apoptosis in neuronal cells. Methods in Molecular Biology (Clifton, N.J.). 399: 125-31. PMID 18309929 DOI: 10.1007/978-1-59745-504-6_9 |
0.318 |
|
| 2006 |
D'Ambrosio C, Arena S, Fulcoli G, Scheinfeld MH, Zhou D, D'Adamio L, Scaloni A. Hyperphosphorylation of JNK-interacting protein 1, a protein associated with Alzheimer disease. Molecular & Cellular Proteomics : McP. 5: 97-113. PMID 16195223 DOI: 10.1074/Mcp.M500226-Mcp200 |
0.736 |
|
| 2005 |
Matsuda S, Giliberto L, Matsuda Y, Davies P, McGowan E, Pickford F, Ghiso J, Frangione B, D'Adamio L. The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production. The Journal of Biological Chemistry. 280: 28912-6. PMID 15983050 DOI: 10.1074/Jbc.C500217200 |
0.477 |
|
| 2005 |
Pardossi-Piquard R, Petit A, Kawarai T, Sunyach C, Alves da Costa C, Vincent B, Ring S, D'Adamio L, Shen J, Müller U, St George Hyslop P, Checler F. Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP. Neuron. 46: 541-54. PMID 15944124 DOI: 10.1016/J.Neuron.2005.04.008 |
0.401 |
|
| 2004 |
Ghersi E, Noviello C, D'Adamio L. Amyloid-beta protein precursor (AbetaPP) intracellular domain-associated protein-1 proteins bind to AbetaPP and modulate its processing in an isoform-specific manner. The Journal of Biological Chemistry. 279: 49105-12. PMID 15347684 DOI: 10.1074/Jbc.M405329200 |
0.836 |
|
| 2004 |
Zhou D, Noviello C, D'Ambrosio C, Scaloni A, D'Adamio L. Growth factor receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail of amyloid beta precursor protein is mediated by its Src homology 2 domain. The Journal of Biological Chemistry. 279: 25374-80. PMID 15054097 DOI: 10.1074/Jbc.M400488200 |
0.675 |
|
| 2004 |
Ghersi E, Vito P, Lopez P, Abdallah M, D'Adamio L. The intracellular localization of amyloid beta protein precursor (AbetaPP) intracellular domain associated protein-1 (AIDA-1) is regulated by AbetaPP and alternative splicing. Journal of Alzheimer's Disease : Jad. 6: 67-78. PMID 15004329 DOI: 10.3233/Jad-2004-6108 |
0.818 |
|
| 2004 |
Papa S, Zazzeroni F, Bubici C, Jayawardena S, Alvarez K, Matsuda S, Nguyen DU, Pham CG, Nelsbach AH, Melis T, De Smaele E, Tang WJ, D'Adamio L, Franzoso G. Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2. Nature Cell Biology. 6: 146-53. PMID 14743220 DOI: 10.1038/Ncb1093 |
0.32 |
|
| 2003 |
Scheinfeld MH, Ghersi E, Davies P, D'Adamio L. Amyloid beta protein precursor is phosphorylated by JNK-1 independent of, yet facilitated by, JNK-interacting protein (JIP)-1. The Journal of Biological Chemistry. 278: 42058-63. PMID 12917434 DOI: 10.1074/Jbc.M304853200 |
0.824 |
|
| 2003 |
Matsuda S, Matsuda Y, D'Adamio L. Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1. The Journal of Biological Chemistry. 278: 38601-6. PMID 12893827 DOI: 10.1074/Jbc.M304379200 |
0.465 |
|
| 2003 |
Noviello C, Vito P, Lopez P, Abdallah M, D'Adamio L. Autosomal recessive hypercholesterolemia protein interacts with and regulates the cell surface level of Alzheimer's amyloid beta precursor protein. The Journal of Biological Chemistry. 278: 31843-7. PMID 12805363 DOI: 10.1074/Jbc.M304133200 |
0.436 |
|
| 2003 |
Scheinfeld MH, Matsuda S, D'Adamio L. JNK-interacting protein-1 promotes transcription of A beta protein precursor but not A beta precursor-like proteins, mechanistically different than Fe65. Proceedings of the National Academy of Sciences of the United States of America. 100: 1729-34. PMID 12563035 DOI: 10.1073/Pnas.0437908100 |
0.717 |
|
| 2002 |
Scheinfeld MH, Ghersi E, Laky K, Fowlkes BJ, D'Adamio L. Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription. The Journal of Biological Chemistry. 277: 44195-201. PMID 12228233 DOI: 10.1074/Jbc.M208110200 |
0.821 |
|
| 2002 |
Borghi R, Pellegrini L, Lacaná E, Diaspro A, Pronzato MA, Vitali A, Roncarati R, Strocchi P, Zaccheo D, D'Adamio L, Tabaton M. Neuronal apoptosis is accompanied by amyloid beta-protein accumulation in the endoplasmic reticulum. Journal of Alzheimer's Disease : Jad. 4: 31-7. PMID 12214016 DOI: 10.3233/Jad-2002-4104 |
0.439 |
|
| 2002 |
Tarr PE, Contursi C, Roncarati R, Noviello C, Ghersi E, Scheinfeld MH, Zambrano N, Russo T, D'Adamio L. Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP. Biochemical and Biophysical Research Communications. 295: 324-9. PMID 12150951 DOI: 10.1016/S0006-291X(02)00678-2 |
0.785 |
|
| 2002 |
Jang IK, Hu R, Lacaná E, D'Adamio L, Gu H. Apoptosis-linked gene 2-deficient mice exhibit normal T-cell development and function. Molecular and Cellular Biology. 22: 4094-100. PMID 12024023 DOI: 10.1128/Mcb.22.12.4094-4100.2002 |
0.349 |
|
| 2002 |
Roncarati R, Sestan N, Scheinfeld MH, Berechid BE, Lopez PA, Meucci O, McGlade JC, Rakic P, D'Adamio L. The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling. Proceedings of the National Academy of Sciences of the United States of America. 99: 7102-7. PMID 12011466 DOI: 10.1073/Pnas.102192599 |
0.755 |
|
| 2002 |
Tarr PE, Roncarati R, Pelicci G, Pelicci PG, D'Adamio L. Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc. The Journal of Biological Chemistry. 277: 16798-804. PMID 11877420 DOI: 10.1074/Jbc.M110286200 |
0.506 |
|
| 2002 |
Scheinfeld MH, Roncarati R, Vito P, Lopez PA, Abdallah M, D'Adamio L. Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP). The Journal of Biological Chemistry. 277: 3767-75. PMID 11724784 DOI: 10.1074/Jbc.M108357200 |
0.783 |
|
| 2001 |
Pellegrini L, Passer BJ, Canelles M, Lefterov I, Ganjei JK, Fowlkes BJ, Koonin EV, D'Adamio L. PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2. Journal of Alzheimer's Disease : Jad. 3: 181-190. PMID 12214059 DOI: 10.3233/Jad-2001-3203 |
0.449 |
|
| 2001 |
Pellegrini L, Passer BJ, Canelles M, Lefterov I, Kelly Ganjei J, Fowlkes BJ, Koonin EV, D'Adamio L. PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2 Journal of Alzheimer's Disease. 3: 181-190. |
0.33 |
|
| 2000 |
Passer B, Pellegrini L, Russo C, Siegel RM, Lenardo MJ, Schettini G, Bachmann M, Tabaton M, D'Adamio L. Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor. Journal of Alzheimer's Disease : Jad. 2: 289-301. PMID 12214090 DOI: 10.3233/Jad-2000-23-408 |
0.517 |
|
| 2000 |
Passer B, Pellegrini L, Russo C, Siegel RM, Lenardo MJ, Schettini G, Bachmann M, Tabaton M, D'Adamio L. Generation of an apoptotic intracellular peptide by γ-secretase cleavage of Alzheimer's amyloid β protein precursor Journal of Alzheimer's Disease. 2: 289-301. |
0.364 |
|
| 1999 |
Pellegrini L, Passer BJ, Tabaton M, Ganjei JK, D'Adamio L. Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8. The Journal of Biological Chemistry. 274: 21011-6. PMID 10409650 DOI: 10.1074/jbc.274.30.21011 |
0.458 |
|
| 1997 |
Vito P, Ghayur T, D'Adamio L. Generation of anti-apoptotic presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavage Journal of Biological Chemistry. 272: 28315-28320. PMID 9353287 DOI: 10.1074/Jbc.272.45.28315 |
0.353 |
|
| 1997 |
D'Adamio L, Lacana' E, Vito P. Functional cloning of genes involved in T-cell receptor-induced programmed cell death Seminars in Immunology. 9: 17-23. PMID 9106304 DOI: 10.1006/Smim.1996.0057 |
0.391 |
|
| 1996 |
Vito P, Wolozin B, Ganjei JK, Iwasaki K, Lacanà E, D'Adamio L. Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3. The Journal of Biological Chemistry. 271: 31025-8. PMID 8940094 DOI: 10.1074/Jbc.271.49.31025 |
0.359 |
|
| 1996 |
Wolozin B, Iwasaki K, Vito P, Ganjei JK, Lacanà E, Sunderland T, Zhao B, Kusiak JW, Wasco W, D'Adamio L. Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation. Science (New York, N.Y.). 274: 1710-3. PMID 8939861 DOI: 10.1126/Science.274.5293.1710 |
0.507 |
|
| 1996 |
Vito P, Lacaná E, D'Adamio L. Interfering with apoptosis: Ca2+-binding protein ALG-2 and Alzheimer's disease gene ALG-3 Science. 271: 521-525. PMID 8560270 DOI: 10.1126/Science.271.5248.521 |
0.376 |
|
| 1989 |
Shipp MA, Vijayaraghavan J, Schmidt EV, Masteller EL, D'Adamio L, Hersh LB, Reinherz EL. Common acute lymphoblastic leukemia antigen (CALLA) is active neutral endopeptidase 24.11 ('enkephalinase'): Direct evidence by cDNA transfection analysis Proceedings of the National Academy of Sciences of the United States of America. 86: 297-301. PMID 2521388 DOI: 10.1073/Pnas.86.1.297 |
0.3 |
|
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