Andrea J. Tenner - Publications

Affiliations: 
University of California, Irvine, Irvine, CA 
Area:
Neuroscience Biology, Immunology

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Year Citation  Score
2023 Petrisko TJ, Gargus M, Chu SH, Selvan P, Whiteson KL, Tenner AJ. Influence of complement protein C1q or complement receptor C5aR1 on gut microbiota composition in wildtype and Alzheimer's mouse models. Journal of Neuroinflammation. 20: 211. PMID 37726739 DOI: 10.1186/s12974-023-02885-9  0.793
2023 Schartz ND, Liang HY, Carvalho K, Chu SH, Mendoza-Arvilla A, Petrisko TJ, Gomez-Arboledas A, Mortazavi A, Tenner AJ. C5aR1 antagonism suppresses inflammatory glial gene expression and alters cellular signaling in an aggressive Alzheimer's model. Biorxiv : the Preprint Server For Biology. PMID 37662399 DOI: 10.1101/2023.08.22.554306  0.799
2022 Gomez-Arboledas A, Carvalho K, Balderrama-Gutierrez G, Chu SH, Liang HY, Schartz ND, Selvan P, Petrisko TJ, Pan MA, Mortazavi A, Tenner AJ. C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer's disease. Acta Neuropathologica Communications. 10: 116. PMID 35978440 DOI: 10.1186/s40478-022-01416-6  0.811
2022 Carvalho K, Schartz ND, Balderrama-Gutierrez G, Liang HY, Chu SH, Selvan P, Gomez-Arboledas A, Petrisko TJ, Fonseca MI, Mortazavi A, Tenner AJ. Modulation of C5a-C5aR1 signaling alters the dynamics of AD progression. Journal of Neuroinflammation. 19: 178. PMID 35820938 DOI: 10.1186/s12974-022-02539-2  0.807
2021 Petrisko TJ, Gomez-Arboledas A, Tenner AJ. Complement as a powerful "influencer" in the brain during development, adulthood and neurological disorders. Advances in Immunology. 152: 157-222. PMID 34844709 DOI: 10.1016/bs.ai.2021.09.003  0.787
2021 Baglietto-Vargas D, Forner S, Cai L, Martini AC, Trujillo-Estrada L, Swarup V, Nguyen MMT, Do Huynh K, Javonillo DI, Tran KM, Phan J, Jiang S, Kramár EA, Nuñez-Diaz C, Balderrama-Gutierrez G, ... ... Tenner AJ, et al. Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology. Nature Communications. 12: 2421. PMID 33893290 DOI: 10.1038/s41467-021-22624-z  0.753
2020 Tenner AJ. Complement-Mediated Events in Alzheimer's Disease: Mechanisms and Potential Therapeutic Targets. Journal of Immunology (Baltimore, Md. : 1950). 204: 306-315. PMID 31907273 DOI: 10.4049/Jimmunol.1901068  0.431
2019 Baglietto-Vargas D, Forner S, Cai L, Martini AC, Trujillo-Estrada L, Jiang S, Kramár E, Nuñez-Diaz C, Shahnawaz M, Matheos DP, Ma X, Da Cunha C, Soto C, Gutierrez A, Moreno-Gonzalez I, ... ... Tenner A, et al. P3-069: HUMAN WILD TYPE Aβ KNOCK-IN MICE AS A BASIS TO STUDY SPORADIC ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P953-P953. DOI: 10.1016/J.Jalz.2019.06.3096  0.365
2018 Tenner AJ, Stevens B, Woodruff TM. New tricks for an ancient system: Physiological and pathological roles of complement in the CNS. Molecular Immunology. PMID 29958698 DOI: 10.1016/J.Molimm.2018.06.264  0.37
2018 Johansson JU, Brubaker WD, Javitz H, Bergen AW, Nishita D, Trigunaite A, Crane A, Ceballos J, Mastroeni D, Tenner AJ, Sabbagh M, Rogers J. Peripheral complement interactions with amyloid β peptide in Alzheimer's disease: Polymorphisms, structure, and function of complement receptor 1. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29792870 DOI: 10.1016/J.Jalz.2018.04.003  0.376
2018 Tenner A, Chu S, Wetsel R, Fonseca M. Influence of C5aR1 signaling on microglial CR3 expression in an Alzheimer's disease mouse model Molecular Immunology. 102: 219. DOI: 10.1016/J.Molimm.2018.06.224  0.359
2018 Tenner A, Chu S, Wetsel R, Cinco R, Gratton E, Fonseca M. Complement proteins associated with synapse proteins in an Alzheimer's disease mouse model lacking C5aR1 Molecular Immunology. 102: 218. DOI: 10.1016/J.Molimm.2018.06.223  0.345
2017 Kim YK, Chu SH, Hsieh JY, Kamoku CM, Tenner AJ, Liu WF, Wang SW. Incorporation of a Ligand Peptide for Immune Inhibitory Receptor LAIR-1 on Biomaterial Surfaces Inhibits Macrophage Inflammatory Responses. Advanced Healthcare Materials. PMID 29083540 DOI: 10.1002/Adhm.201700707  0.328
2017 Hernandez MX, Jiang S, Cole TA, Chu SH, Fonseca MI, Fang MJ, Hohsfield LA, Torres MD, Green KN, Wetsel RA, Mortazavi A, Tenner AJ. Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss. Molecular Neurodegeneration. 12: 66. PMID 28923083 DOI: 10.1186/S13024-017-0210-Z  0.766
2017 Crane A, Brubaker WD, Johansson JU, Trigunaite A, Ceballos J, Bradt B, Glavis-Bloom C, Wallace TL, Tenner AJ, Rogers J. Peripheral complement interactions with amyloid β peptide in Alzheimer's disease: 2. Relationship to Aβ immunotherapy. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28755839 DOI: 10.1016/J.Jalz.2017.04.015  0.367
2017 Chen EY, Chu S, Gov L, Kim YK, Lodoen MB, Tenner AJ, Liu WF. CD200 modulates macrophage cytokine secretion and phagocytosis in response to poly(lactic co-glycolic acid) microparticles and films. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 5: 1574-1584. PMID 28736613 DOI: 10.1039/C6Tb02269C  0.315
2017 Thielens NM, Tedesco F, Bohlson SS, Gaboriaud C, Tenner AJ. C1q: A fresh look upon an old molecule. Molecular Immunology. PMID 28601358 DOI: 10.1016/J.Molimm.2017.05.025  0.36
2017 Brubaker WD, Crane A, Johansson JU, Yen K, Garfinkel K, Mastroeni D, Asok P, Bradt B, Sabbagh M, Wallace TL, Glavis-Bloom C, Tenner AJ, Rogers J. Peripheral complement interactions with amyloid β peptides in Alzheimer's disease: Erythrocyte clearance of amyloid β peptides. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28475854 DOI: 10.1016/J.Jalz.2017.03.010  0.34
2017 Fonseca MI, Chu SH, Hernandez MX, Fang MJ, Modarresi L, Selvan P, MacGregor GR, Tenner AJ. Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain. Journal of Neuroinflammation. 14: 48. PMID 28264694 DOI: 10.1186/S12974-017-0814-9  0.408
2017 Hernandez MX, Namiranian P, Nguyen E, Fonseca MI, Tenner AJ. C5a Increases the Injury to Primary Neurons Elicited by Fibrillar Amyloid Beta. Asn Neuro. 9: 1759091416687871. PMID 28078911 DOI: 10.1177/1759091416687871  0.398
2017 Tenner A. THE BIOLOGY OF COMPLEMENT RISK GENES IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 13: P1448. DOI: 10.1016/J.Jalz.2017.07.486  0.316
2016 Fonseca MI, Chu S, Pierce AL, Brubaker WD, Hauhart RE, Mastroeni D, Clarke EV, Rogers J, Atkinson JP, Tenner AJ. Analysis of the Putative Role of CR1 in Alzheimer's Disease: Genetic Association, Expression and Function. Plos One. 11: e0149792. PMID 26914463 DOI: 10.1371/Journal.Pone.0149792  0.683
2016 Hernandez MX, Fonseca MI, Chu S, Tenner AJ. Role of microglial C5aR1 in the Arctic Alzheimer's Disease mouse model Immunobiology. 221: 1187-1188. DOI: 10.1016/J.Imbio.2016.06.140  0.392
2016 Fonseca MI, Chu S, Hernandez M, Fang M, Modarresi L, Tenner AJ. Microglia specific ablation of C1q gene definitively demonstrates microglia as the dominant source of C1q in both normal mouse brain and in models of Alzheimer's disease Immunobiology. 221: 1149. DOI: 10.1016/J.Imbio.2016.06.057  0.385
2015 Linnartz-Gerlach B, Schuy C, Shahraz A, Tenner AJ, Neumann H. Sialylation of neurites inhibits complement-mediated macrophage removal in a human macrophage-neuron Co-Culture System. Glia. PMID 26257016 DOI: 10.1002/Glia.22901  0.365
2015 Rice RA, Spangenberg EE, Yamate-Morgan H, Lee RJ, Arora RP, Hernandez MX, Tenner AJ, West BL, Green KN. Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 9977-89. PMID 26156998 DOI: 10.1523/Jneurosci.0336-15.2015  0.353
2015 Woodruff TM, Tenner AJ. A Commentary On: "NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer's Disease". A cautionary note regarding C3aR. Frontiers in Immunology. 6: 220. PMID 25999955 DOI: 10.3389/Fimmu.2015.00220  0.407
2015 Clarke EV, Weist BM, Walsh CM, Tenner AJ. Complement protein C1q bound to apoptotic cells suppresses human macrophage and dendritic cell-mediated Th17 and Th1 T cell subset proliferation. Journal of Leukocyte Biology. 97: 147-60. PMID 25381385 DOI: 10.1189/Jlb.3A0614-278R  0.678
2015 Rogers J, Brubaker W, Johansson J, Bergen A, Nishita D, Asok P, Jimenez L, Crane A, Sabbagh MN, Mastroeni D, Liebsack C, Rangel A, Chu S, Tenner A. O2-14-03: Erythrocyte cr1 and its relationship to Alzheimer's disease pathogenic mechanisms and immunization strategies Alzheimer's & Dementia. 11: P208-P209. DOI: 10.1016/J.Jalz.2015.07.210  0.334
2014 Clarke EV, Tenner AJ. Complement modulation of T cell immune responses during homeostasis and disease. Journal of Leukocyte Biology. 96: 745-56. PMID 25210145 DOI: 10.1189/Jlb.3Mr0214-109R  0.709
2014 Ueno N, Harker KS, Clarke EV, McWhorter FY, Liu WF, Tenner AJ, Lodoen MB. Real-time imaging of Toxoplasma-infected human monocytes under fluidic shear stress reveals rapid translocation of intracellular parasites across endothelial barriers. Cellular Microbiology. 16: 580-95. PMID 24245749 DOI: 10.1111/Cmi.12239  0.654
2013 Clarke EV, Benoit ME, Tenner AJ. Purification of Human Monocytes and Lymphocyte Populations by Counter Current Elutriation- A Short Protocol. Bio-Protocol. 3. PMID 27081666  0.65
2013 Benoit ME, Clarke EV, Tenner AJ. C1q Binding to and Uptake of Apoptotic Lymphocytes by Human Monocyte-derived Macrophages. Bio-Protocol. 3. PMID 27064237  0.661
2013 Stephan AH, Madison DV, Mateos JM, Fraser DA, Lovelett EA, Coutellier L, Kim L, Tsai HH, Huang EJ, Rowitch DH, Berns DS, Tenner AJ, Shamloo M, Barres BA. A dramatic increase of C1q protein in the CNS during normal aging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13460-74. PMID 23946404 DOI: 10.1523/Jneurosci.1333-13.2013  0.336
2013 Fonseca MI, McGuire SO, Counts SE, Tenner AJ. Complement activation fragment C5a receptors, CD88 and C5L2, are associated with neurofibrillary pathology. Journal of Neuroinflammation. 10: 25. PMID 23394121 DOI: 10.1186/1742-2094-10-25  0.445
2013 Benoit ME, Hernandez MX, Dinh ML, Benavente F, Vasquez O, Tenner AJ. C1q-induced LRP1B and GPR6 proteins expressed early in Alzheimer disease mouse models, are essential for the C1q-mediated protection against amyloid-β neurotoxicity. The Journal of Biological Chemistry. 288: 654-65. PMID 23150673 DOI: 10.1074/Jbc.M112.400168  0.442
2012 Cribbs DH, Berchtold NC, Perreau V, Coleman PD, Rogers J, Tenner AJ, Cotman CW. Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study. Journal of Neuroinflammation. 9: 179. PMID 22824372 DOI: 10.1186/1742-2094-9-179  0.359
2012 Benoit ME, Clarke EV, Morgado P, Fraser DA, Tenner AJ. Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 5682-93. PMID 22523386 DOI: 10.4049/Jimmunol.1103760  0.698
2012 Linnartz B, Kopatz J, Tenner AJ, Neumann H. Sialic acid on the neuronal glycocalyx prevents complement C1 binding and complement receptor-3-mediated removal by microglia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 946-52. PMID 22262892 DOI: 10.1523/Jneurosci.3830-11.2012  0.369
2012 Benoit ME, Hernandez MX, Dinh ML, Benavente F, Vasquez O, Tenner AJ. C1q induces a program of gene expression in amyloid beta injured neurons necessary for neuron survival Immunobiology. 217: 1143. DOI: 10.1016/J.Imbio.2012.08.041  0.324
2011 Veerhuis R, Nielsen HM, Tenner AJ. Complement in the brain. Molecular Immunology. 48: 1592-603. PMID 21546088 DOI: 10.1016/J.Molimm.2011.04.003  0.459
2011 Benoit ME, Tenner AJ. Complement protein C1q-mediated neuroprotection is correlated with regulation of neuronal gene and microRNA expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3459-69. PMID 21368058 DOI: 10.1523/Jneurosci.3932-10.2011  0.403
2011 Fonseca MI, Chu SH, Berci AM, Benoit ME, Peters DG, Kimura Y, Tenner AJ. Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease. Journal of Neuroinflammation. 8: 4. PMID 21235806 DOI: 10.1186/1742-2094-8-4  0.452
2010 Fraser DA, Tenner AJ. Innate immune proteins C1q and mannan-binding lectin enhance clearance of atherogenic lipoproteins by human monocytes and macrophages. Journal of Immunology (Baltimore, Md. : 1950). 185: 3932-9. PMID 20833838 DOI: 10.4049/Jimmunol.1002080  0.351
2010 Ager RR, Fonseca MI, Chu SH, Sanderson SD, Taylor SM, Woodruff TM, Tenner AJ. Microglial C5aR (CD88) expression correlates with amyloid-beta deposition in murine models of Alzheimer's disease. Journal of Neurochemistry. 113: 389-401. PMID 20132482 DOI: 10.1111/J.1471-4159.2010.06595.X  0.785
2010 Fraser DA, Pisalyaput K, Tenner AJ. C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production. Journal of Neurochemistry. 112: 733-43. PMID 19919576 DOI: 10.1111/J.1471-4159.2009.06494.X  0.785
2010 Woodruff TM, Ager RR, Tenner AJ, Noakes PG, Taylor SM. The role of the complement system and the activation fragment C5a in the central nervous system. Neuromolecular Medicine. 12: 179-92. PMID 19763906 DOI: 10.1007/S12017-009-8085-Y  0.771
2010 Cole TA, Pisalyaput K, Benoit ME, Rowther N, Tenner AJ. Greater C5a generation in the BUB/BnJ mouse: Designing better mouse models to study the role of complement in degenerative diseases Molecular Immunology. 47: 2274-2274. DOI: 10.1016/J.Molimm.2010.05.227  0.759
2009 Fraser DA, Laust AK, Nelson EL, Tenner AJ. C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 6175-85. PMID 19864605 DOI: 10.4049/Jimmunol.0902232  0.396
2009 Fonseca MI, Ager RR, Chu SH, Yazan O, Sanderson SD, LaFerla FM, Taylor SM, Woodruff TM, Tenner AJ. Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease. Journal of Immunology (Baltimore, Md. : 1950). 183: 1375-83. PMID 19561098 DOI: 10.4049/Jimmunol.0901005  0.79
2009 Klos A, Tenner AJ, Johswich KO, Ager RR, Reis ES, Köhl J. The role of the anaphylatoxins in health and disease. Molecular Immunology. 46: 2753-66. PMID 19477527 DOI: 10.1016/J.Molimm.2009.04.027  0.764
2008 Alexander JJ, Anderson AJ, Barnum SR, Stevens B, Tenner AJ. The complement cascade: Yin-Yang in neuroinflammation--neuro-protection and -degeneration. Journal of Neurochemistry. 107: 1169-87. PMID 18786171 DOI: 10.1111/J.1471-4159.2008.05668.X  0.392
2008 Zhou J, Fonseca MI, Pisalyaput K, Tenner AJ. Complement C3 and C4 expression in C1q sufficient and deficient mouse models of Alzheimer's disease. Journal of Neurochemistry. 106: 2080-92. PMID 18624920 DOI: 10.1111/J.1471-4159.2008.05558.X  0.8
2008 Lillis AP, Greenlee MC, Mikhailenko I, Pizzo SV, Tenner AJ, Strickland DK, Bohlson SS. Murine low-density lipoprotein receptor-related protein 1 (LRP) is required for phagocytosis of targets bearing LRP ligands but is not required for C1q-triggered enhancement of phagocytosis. Journal of Immunology (Baltimore, Md. : 1950). 181: 364-73. PMID 18566402 DOI: 10.4049/Jimmunol.181.1.364  0.383
2008 Li M, Ager RR, Fraser DA, Tjokro NO, Tenner AJ. Development of a humanized C1q A chain knock-in mouse: assessment of antibody independent beta-amyloid induced complement activation. Molecular Immunology. 45: 3244-52. PMID 18400300 DOI: 10.1016/J.Molimm.2008.02.022  0.76
2008 Pisalyaput K, Tenner AJ. Complement component C1q inhibits beta-amyloid- and serum amyloid P-induced neurotoxicity via caspase- and calpain-independent mechanisms. Journal of Neurochemistry. 104: 696-707. PMID 17986223 DOI: 10.1111/J.1471-4159.2007.05012.X  0.797
2008 Fraser DA, Pisalyaput K, Vogler EC, Tenner AJ. A role for complement components C1q and C3 in the clearance of apoptotic cells by microglia The Faseb Journal. 22: 554-554. DOI: 10.1096/Fasebj.22.2_Supplement.554  0.768
2008 Ager R, Fonseca M, Chu S, Yazan O, Woodruff T, Sanderson S, Taylor S, Tenner A. Decreases in Alzheimer's disease like pathology associated with C5aR inhibition correlate with improved performance in a passive avoidance task Molecular Immunology. 45: 4109. DOI: 10.1016/J.Molimm.2008.08.042  0.734
2008 Fonseca MI, Ager RR, Woodruff TM, Chu S, Yazan O, Sanderson S, LaFerla FM, Taylor SM, Tenner AJ. O4-02-08: Chronic treatment with C5a antagonist decreases pathology in two mouse models of Alzheimer's disease Alzheimer's & Dementia. 4: T188-T188. DOI: 10.1016/J.Jalz.2008.05.516  0.747
2008 Tenner AJ, Pisalyaput K. Central nervous system diseases and inflammation: The complement system in the CNS: Thinking again Central Nervous System Diseases and Inflammation. 153-174. DOI: 10.1007/978-0-387-73894-9_8  0.77
2007 Fraser DA, Arora M, Bohlson SS, Lozano E, Tenner AJ. Generation of inhibitory NFkappaB complexes and phosphorylated cAMP response element-binding protein correlates with the anti-inflammatory activity of complement protein C1q in human monocytes. The Journal of Biological Chemistry. 282: 7360-7. PMID 17209050 DOI: 10.1074/Jbc.M605741200  0.351
2007 Bohlson SS, Fraser DA, Tenner AJ. Complement proteins C1q and MBL are pattern recognition molecules that signal immediate and long-term protective immune functions. Molecular Immunology. 44: 33-43. PMID 16908067 DOI: 10.1016/J.Molimm.2006.06.021  0.387
2007 Zhou J, Fonseca MI, Billings-Luhr L, Kayed R, Glabe CG, LaFerla F, Tenner AJ. Effect of immunization with the oligomeric form of the Aβ peptide: Reduction of senile plaque area, decreased complement C3 deposition and synthesis, and decline in behavioral function in a murine model of Alzheimer's disease Molecular Immunology. 44: 264-265. DOI: 10.1016/J.Molimm.2006.07.277  0.383
2007 Pisalyaput K, Tenner AJ. Complement protein C1q enhances neuronal survival and protects against specific insults via a caspase- and calpain-independent mechanism Molecular Immunology. 44: 229. DOI: 10.1016/J.Molimm.2006.07.192  0.76
2006 Tenner AJ, Fonseca MI. The double-edged flower: roles of complement protein C1q in neurodegenerative diseases. Advances in Experimental Medicine and Biology. 586: 153-76. PMID 16893071 DOI: 10.1007/0-387-34134-X_11  0.455
2006 Chong YH, Shin YJ, Lee EO, Kayed R, Glabe CG, Tenner AJ. ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures. The Journal of Biological Chemistry. 281: 20315-25. PMID 16714296 DOI: 10.1074/Jbc.M601016200  0.39
2006 Fraser DA, Bohlson SS, Jasinskiene N, Rawal N, Palmarini G, Ruiz S, Rochford R, Tenner AJ. C1q and MBL, components of the innate immune system, influence monocyte cytokine expression. Journal of Leukocyte Biology. 80: 107-16. PMID 16617157 DOI: 10.1189/Jlb.1105683  0.351
2006 Yan Leung BP, Doty KR, Miller CJ, Vesling AW, Uchoa MF, Im KW, Gate D, Quihuis AM, Guillot-Sestier M, Rodriguez J, Chang KT, Fahmy T, Tenner A, Colonna M, Town T. O4-02-03: PHYSICAL INTERACTION OF TREM2 AND C1Q IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1403-P1403. DOI: 10.1016/J.Jalz.2018.06.2917  0.305
2006 Baglietto-Vargas D, Cai L, Forner S, Martini A, Trujillo-Estrada L, Cunha C, Mortazavi A, Wood MA, Green KN, Macgregor GR, Tenner A, LaFerla F. O1-01-04: HAβ-KI: A KNOCK-IN MOUSE MODEL FOR SPORADIC ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P213-P213. DOI: 10.1016/J.Jalz.2018.06.2333  0.334
2006 Lamb BT, Oblak AL, Williams HM, Baglietto-Vargas D, Wood MA, Mortazavi A, Green KN, Carter GW, Sukoff Rizzo SJ, Territo P, Sasner M, Macgregor GR, Tenner A, LaFerla F, Howell G. P1-131: MODEL-AD: LATE-ONSET ALZHEIMER'S DISEASE MODELS Alzheimer's & Dementia. 14: P321-P321. DOI: 10.1016/J.Jalz.2018.06.134  0.347
2006 Oblak AL, Williams HM, Baglietto-Vargas D, Mortazavi A, Wood MA, Green KN, Carter GW, Territo P, Sukoff Rizzo SJ, Sasner M, Macgregor GR, Tenner A, LaFerla F, Howell G, Lamb BT. P1-130: MODEL-AD: CHARACTERIZATION OF FAMILIAL AD MODELS (5XFAD, APP/PS1, HTAU, 3XTG-AD) Alzheimer's & Dementia. 14: P321-P321. DOI: 10.1016/J.Jalz.2018.06.133  0.306
2005 Zhou J, Fonseca MI, Kayed R, Hernandez I, Webster SD, Yazan O, Cribbs DH, Glabe CG, Tenner AJ. Novel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease. Journal of Neuroinflammation. 2: 28. PMID 16332263 DOI: 10.1186/1742-2094-2-28  0.395
2005 Fan R, Tenner AJ. Differential regulation of Abeta42-induced neuronal C1q synthesis and microglial activation. Journal of Neuroinflammation. 2: 1. PMID 15642121 DOI: 10.1186/1742-2094-2-1  0.376
2004 Li M, Pisalyaput K, Galvan M, Tenner AJ. Macrophage colony stimulatory factor and interferon-γ trigger distinct mechanisms for augmentation of β-amyloid-induced microglia-mediated neurotoxicity Journal of Neurochemistry. 91: 623-633. PMID 15485493 DOI: 10.1111/J.1471-4159.2004.02765.X  0.78
2004 Fonseca MI, Zhou J, Botto M, Tenner AJ. Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6457-65. PMID 15269255 DOI: 10.1523/Jneurosci.0901-04.2004  0.418
2004 Fonseca MI, Kawas CH, Troncoso JC, Tenner AJ. Neuronal localization of C1q in preclinical Alzheimer's disease. Neurobiology of Disease. 15: 40-6. PMID 14751769 DOI: 10.1016/J.Nbd.2003.09.004  0.4
2004 Fan R, Tenner AJ. Complement C1q expression induced by Abeta in rat hippocampal organotypic slice cultures. Experimental Neurology. 185: 241-53. PMID 14736505 DOI: 10.1016/J.Expneurol.2003.09.023  0.422
2003 Maruyama H, Galvan M, Waffarn F, Tenner AJ. Human cord blood leukocyte innate immune responses to defense collagens. Pediatric Research. 54: 724-31. PMID 12904598 DOI: 10.1203/01.Pdr.0000085804.00768.4D  0.354
2003 Park M, Tenner AJ. Cell surface expression of C1qRP/CD93 is stabilized by O-glycosylation. Journal of Cellular Physiology. 196: 512-22. PMID 12891708 DOI: 10.1002/Jcp.10332  0.577
2001 Tenner AJ. Complement in Alzheimer's disease: Opportunities for modulating protective and pathogenic events Neurobiology of Aging. 22: 849-861. PMID 11754992 DOI: 10.1016/S0197-4580(01)00301-3  0.438
2001 Fonseca MI, Carpenter PM, Park M, Palmarini G, Nelson EL, Tenner AJ. C1qR(P), a myeloid cell receptor in blood, is predominantly expressed on endothelial cells in human tissue. Journal of Leukocyte Biology. 70: 793-800. PMID 11698500 DOI: 10.1189/Jlb.70.5.793  0.608
2001 Jack DL, Read RC, Tenner AJ, Frosch M, Turner MW, Klein NJ. Mannose-binding lectin regulates the inflammatory response of human professional phagocytes to Neisseria meningitidis serogroup B Journal of Infectious Diseases. 184: 1152-1162. PMID 11598838 DOI: 10.1086/323803  0.328
2001 Arora M, Munoz E, Tenner AJ. Identification of a Site on Mannan-binding Lectin Critical for Enhancement of Phagocytosis Journal of Biological Chemistry. 276: 43087-43094. PMID 11533031 DOI: 10.1074/Jbc.M105455200  0.346
2001 Webster SD, Galvan MD, Ferran E, Garzon-Rodriguez W, Glabe CG, Tenner AJ. Antibody-mediated phagocytosis of the amyloid beta-peptide in microglia is differentially modulated by C1q. Journal of Immunology (Baltimore, Md. : 1950). 166: 7496-503. PMID 11390503 DOI: 10.4049/Jimmunol.166.12.7496  0.408
2001 Head E, Azizeh BY, Lott IT, Tenner AJ, Cotman CW, Cribbs DH. Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome. Neurobiology of Disease. 8: 252-65. PMID 11300721 DOI: 10.1006/Nbdi.2000.0380  0.369
2001 Matsuoka Y, Picciano M, Malester B, LaFrancois J, Zehr C, Daeschner JM, Olschowka JA, Fonseca MI, O'Banion MK, Tenner AJ, Lemere CA, Duff K. Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease. The American Journal of Pathology. 158: 1345-54. PMID 11290552 DOI: 10.1016/S0002-9440(10)64085-0  0.389
2000 Kim TS, Park M, Nepomuceno RR, Palmarini G, Winokur S, Cotman CA, Bengtsson U, Tenner AJ. Characterization of the murine homolog of C1qR(P): identical cellular expression pattern, chromosomal location and functional activity of the human and murine C1qR(P). Molecular Immunology. 37: 377-89. PMID 11074255 DOI: 10.1016/S0161-5890(00)00057-2  0.599
2000 Yokota T, Oritani K, Takahashi I, Ishikawa J, Matsuyama A, Ouchi N, Kihara S, Funahashi T, Tenner AJ, Tomiyama Y, Matsuzawa Y. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages Blood. 96: 1723-1732. PMID 10961870 DOI: 10.1182/Blood.V96.5.1723.H8001723_1723_1732  0.354
2000 Azizeh BY, Head E, Ibrahim MA, Torp R, Tenner AJ, Kim RC, Lott IT, Cotman CW. Molecular dating of senile plaques in the brains of individuals with Down syndrome and in aged dogs. Experimental Neurology. 163: 111-22. PMID 10785449 DOI: 10.1006/Exnr.2000.7359  0.332
2000 Webster SD, Yang AJ, Margol L, Garzon-Rodriguez W, Glabe CG, Tenner AJ. Complement component C1q modulates the phagocytosis of Abeta by microglia. Experimental Neurology. 161: 127-38. PMID 10683279 DOI: 10.1006/Exnr.1999.7260  0.359
2000 Webster SD, Park M, Fonseca MI, Tenner AJ. Structural and functional evidence for microglial expression of C1qR(P), the C1q receptor that enhances phagocytosis. Journal of Leukocyte Biology. 67: 109-16. PMID 10648005 DOI: 10.1002/Jlb.67.1.109  0.645
2000 Park M, Tenner AJ. Glycosylation stabilizes cell surface expression of C1qRp Immunopharmacology. 49: 40. DOI: 10.1016/S0162-3109(00)80112-5  0.547
1999 Webster SD, Tenner AJ, Poulos TL, Cribbs DH. The mouse C1q A-chain sequence alters beta-amyloid-induced complement activation. Neurobiology of Aging. 20: 297-304. PMID 10588577 DOI: 10.1016/S0197-4580(99)00020-2  0.392
1999 Huang J, Kim LJ, Mealey R, Marsh HC, Zhang Y, Tenner AJ, Connolly ES, Pinsky DJ. Neuronal protection in stroke by an sLe(x)-glycosylated complement inhibitory protein Science. 285: 595-599. PMID 10417391 DOI: 10.1126/Science.285.5427.595  0.317
1999 Fonseca MI, Head E, Velazquez P, Cotman CW, Tenner AJ. The presence of isoaspartic acid in beta-amyloid plaques indicates plaque age. Experimental Neurology. 157: 277-88. PMID 10364440 DOI: 10.1006/Exnr.1999.7058  0.358
1999 Nepomuceno RR, Ruiz S, Park M, Tenner AJ. C1qRP is a heavily O-glycosylated cell surface protein involved in the regulation of phagocytic activity. Journal of Immunology (Baltimore, Md. : 1950). 162: 3583-9. PMID 10092817  0.564
1999 Eggleton P, Reid KB, Tenner AJ. C1q--how many functions? How many receptors? Trends in Cell Biology. 8: 428-31. PMID 9854308 DOI: 10.1016/S0962-8924(98)01373-7  0.338
1998 Tenner AJ. C1q receptors: Regulating specific functions of phagocytic cells Immunobiology. 199: 250-264. PMID 9777410 DOI: 10.1016/S0171-2985(98)80031-4  0.309
1998 He XP, Patel M, Whitney KD, Janumpalli S, Tenner A, McNamara JO. Glutamate receptor GluR3 antibodies and death of cortical cells. Neuron. 20: 153-63. PMID 9459451 DOI: 10.1016/S0896-6273(00)80443-2  0.359
1997 Cribbs DH, Velazquez P, Soreghan B, Glabe CG, Tenner AJ. Complement activation by cross-linked truncated and chimeric full-length beta-amyloid. Neuroreport. 8: 3457-62. PMID 9427307 DOI: 10.1097/00001756-199711100-00009  0.307
1997 Webster S, Lue LF, Brachova L, Tenner AJ, McGeer PL, Terai K, Walker DG, Bradt B, Cooper NR, Rogers J. Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease. Neurobiology of Aging. 18: 415-21. PMID 9330973 DOI: 10.1016/S0197-4580(97)00042-0  0.41
1997 Nepomuceno RR, Henschen-Edman AH, Burgess WH, Tenner AJ. cDNA cloning and primary structure analysis of C1qR(p), the human C1q/MBL/SPA receptor that mediates enhanced phagocytosis in vitro Immunity. 6: 119-129. PMID 9047234 DOI: 10.1016/S1074-7613(00)80419-7  0.304
1997 Velazquez P, Cribbs DH, Poulos TL, Tenner AJ. Aspartate residue 7 in amyloid β-protein is critical for classical complement pathway activation: Implications for Alzheimer's disease pathogenesis Nature Medicine. 3: 77-79. PMID 8986745 DOI: 10.1038/Nm0197-77  0.423
1996 Cotman CW, Tenner AJ, Cummings BJ. beta-Amyloid converts an acute phase injury response to chronic injury responses. Neurobiology of Aging. 17: 723-31. PMID 8892345 DOI: 10.1016/0197-4580(96)00117-0  0.349
1996 Afagh A, Cummings BJ, Cribbs DH, Cotman CW, Tenner AJ. Localization and cell association of C1q in Alzheimer's disease brain. Experimental Neurology. 138: 22-32. PMID 8593893 DOI: 10.1006/Exnr.1996.0043  0.42
1995 Ruiz S, Henschen-Edman AH, Tenner AJ. Localization of the site on the complement component C1q required for the stimulation of neutrophil superoxide production Journal of Biological Chemistry. 270: 30627-30634. PMID 8530499 DOI: 10.1074/Jbc.270.51.30627  0.329
1995 Tenner AJ, Robinson SL, Ezekowitz RAB. Mannose binding protein (MBP) enhances mononuclear phagocyte function via a receptor that contains the 126,000 Mr component of the Clq receptor Immunity. 3: 485-493. PMID 7584139 DOI: 10.1016/1074-7613(95)90177-9  0.35
1995 Korotzer AR, Watt J, Cribbs D, Tenner AJ, Burdick D, Glabe C, Cotman CW. Cultured rat microglia express C1q and receptor for C1q: implications for amyloid effects on microglia. Experimental Neurology. 134: 214-21. PMID 7556541 DOI: 10.1006/Exnr.1995.1051  0.419
1994 Smyth MD, Cribbs DH, Tenner AJ, Shankle WR, Dick M, Kesslak JP, Cotman CW. Decreased levels of C1q in cerebrospinal fluid of living Alzheimer patients correlate with disease state. Neurobiology of Aging. 15: 609-14. PMID 7824052 DOI: 10.1016/0197-4580(94)00055-7  0.328
1989 Rimoldi MT, Tenner AJ, Bobak DA, Joiner KA. Complement component C1q enhances invasion of human mononuclear phagocytes and fibroblasts by Trypanosoma cruzi trypomastigotes Journal of Clinical Investigation. 84: 1982-1989. PMID 2687332 DOI: 10.1172/Jci114388  0.305
1989 Schweinle JE, Ezekowitz RAB, Tenner AJ, Kuhlman M, Joiner KA. Human mannose-binding protein activates the alternative complement pathway and enhances serum bactericidal activity on a mannose-rich isolate of Salmonella Journal of Clinical Investigation. 84: 1821-1829. PMID 2592561 DOI: 10.1172/Jci114367  0.332
1988 Bobak DA, Frank MM, Tenner AJ. C1q acts synergistically with phorbol dibutyrate to activate CR1-mediated phagocytosis by human mononuclear phagocytes. European Journal of Immunology. 18: 2001-7. PMID 2975599 DOI: 10.1002/Eji.1830181220  0.347
Low-probability matches (unlikely to be authored by this person)
2005 Bohlson SS, Zhang M, Ortiz CE, Tenner AJ. CD93 interacts with the PDZ domain-containing adaptor protein GIPC: implications in the modulation of phagocytosis. Journal of Leukocyte Biology. 77: 80-9. PMID 15459234 DOI: 10.1189/Jlb.0504305  0.295
2000 Tacnet P, Galvan M, Chevallier S, Glabe C, Tenner A, Arlaud G. C1 activation by amyloid β fibrils. Evidence for a binding site for Aβ on the C1q globular regions Immunopharmacology. 49: 16. DOI: 10.1016/S0162-3109(00)80039-9  0.295
2020 Schartz ND, Tenner AJ. The good, the bad, and the opportunities of the complement system in neurodegenerative disease. Journal of Neuroinflammation. 17: 354. PMID 33239010 DOI: 10.1186/s12974-020-02024-8  0.294
1995 Goodman EB, Anderson DC, Tenner AJ. C1q triggers neutrophil superoxide production by a unique CD18-dependent mechanism Journal of Leukocyte Biology. 58: 168-176. PMID 7643012 DOI: 10.1002/Jlb.58.2.168  0.292
1989 Schweinle JE, Hitchcock PJ, Tenner AJ, Hammer CH, Frank MM, Joiner KA. Interaction of Neisseria gonorrhoeae with classical complement components, C1-inhibitor, and a monoclonal antibody directed against the Neisserial H.8 antigen. The Journal of Clinical Investigation. 83: 397-403. PMID 2492308 DOI: 10.1172/Jci113897  0.29
2006 Osmers I, Szalai AJ, Tenner AJ, Barnum SR. Complement in BuB/BnJ mice revisited: serum C3 levels and complement opsonic activity are not elevated. Molecular Immunology. 43: 1722-5. PMID 16310250 DOI: 10.1016/J.Molimm.2005.10.004  0.288
2005 Bohlson SS, Silva R, Fonseca MI, Tenner AJ. CD93 is rapidly shed from the surface of human myeloid cells and the soluble form is detected in human plasma. Journal of Immunology (Baltimore, Md. : 1950). 175: 1239-47. PMID 16002728 DOI: 10.4049/Jimmunol.175.2.1239  0.287
2022 Bohlson SS, Tenner AJ. Complement in the Brain: Contributions to Neuroprotection, Neuronal Plasticity, and Neuroinflammation. Annual Review of Immunology. PMID 36750318 DOI: 10.1146/annurev-immunol-101921-035639  0.285
2020 Markarian M, Krattli RP, Baddour JD, Alikhani L, Giedzinski E, Usmani MT, Agrawal A, Baulch JE, Tenner AJ, Acharya MM. Glia-selective deletion of complement C1q prevents radiation-induced cognitive deficits and neuroinflammation. Cancer Research. PMID 33323383 DOI: 10.1158/0008-5472.CAN-20-2565  0.28
2010 Zekavat G, Mozaffari R, Arias VJ, Rostami SY, Badkerhanian A, Tenner AJ, Nichols KE, Naji A, Noorchashm H. A novel CD93 polymorphism in non-obese diabetic (NOD) and NZB/W F1 mice is linked to a CD4+ iNKT cell deficient state. Immunogenetics. 62: 397-407. PMID 20387063 DOI: 10.1007/S00251-010-0442-3  0.279
2000 Webster S, Galvan M, Tenner A. C1q enhances antibody-mediated uptake of the amyloid β-peptide by microglia Immunopharmacology. 49: 15. DOI: 10.1016/S0162-3109(00)80037-5  0.279
1999 Tenner AJ. Membrane receptors for soluble defense collagens Current Opinion in Immunology. 11: 34-41. PMID 10047541 DOI: 10.1016/S0952-7915(99)80007-7  0.277
2005 Zhang M, Bohlson SS, Dy M, Tenner AJ. Modulated interaction of the ERM protein, moesin, with CD93. Immunology. 115: 63-73. PMID 15819698 DOI: 10.1111/J.1365-2567.2005.02120.X  0.276
1997 Satou T, Cummings BJ, Head E, Nielson KA, Hahn FF, Milgram NW, Velazquez P, Cribbs DH, Tenner AJ, Cotman CW. The progression of beta-amyloid deposition in the frontal cortex of the aged canine. Brain Research. 774: 35-43. PMID 9452189 DOI: 10.1016/S0006-8993(97)81684-8  0.275
2002 Danet GH, Luongo JL, Butler G, Lu MM, Tenner AJ, Simon MC, Bonnet DA. C1qRp defines a new human stem cell population with hematopoietic and hepatic potential. Proceedings of the National Academy of Sciences of the United States of America. 99: 10441-5. PMID 12140365 DOI: 10.1073/Pnas.162104799  0.275
2019 Bohlson SS, Garred P, Kemper C, Tenner AJ. Complement Nomenclature-Deconvoluted. Frontiers in Immunology. 10: 1308. PMID 31231398 DOI: 10.3389/Fimmu.2019.01308  0.272
1979 Tenner AJ, Scheffler IE. Lipid‐saccharide intermediates and glycoprotein biosynthesis in a temperature‐sensitive Chinese hamster cell mutant Journal of Cellular Physiology. 98: 251-265. PMID 217883 DOI: 10.1002/Jcp.1040980202  0.271
1997 Tenner AJ. C1q receptors: Opportunities for selectively regulating protective and detrimental responses Clinical Immunology Newsletter. 17: 173-177. DOI: 10.1016/S0197-1859(00)80026-6  0.271
2004 Tenner AJ. Influence of innate immune responses on autoimmunity. Autoimmunity. 37: 83-4. PMID 15293877 DOI: 10.1080/08916930410001690067  0.27
2010 Benoit M, Tenner AJ. Regulation of neuronal gene and miRNA expression by the complement protein C1q associated with neuroprotection Molecular Immunology. 47: 2250-2251. DOI: 10.1016/J.Molimm.2010.05.161  0.269
1977 Tenner A, Zieg J, Scheffler IE. Glycoprotein synthesis in a temperature-sensitive Chinese hamster cell cycle mutant. Journal of Cellular Physiology. 90: 145-60. PMID 557044 DOI: 10.1002/Jcp.1040900202  0.267
1985 Bohnsack JF, Tenner AJ, Laurie GW, Kleinman HK, Martin GR, Brown EJ. The C1q subunit of the first component of complement binds to laminin: A mechanism for the deposition and retention of immune complexes in basement membrane Proceedings of the National Academy of Sciences of the United States of America. 82: 3824-3828. PMID 2987948 DOI: 10.1073/Pnas.82.11.3824  0.265
2019 Wyman D, Balderrama-Gutierrez G, Reese F, Jiang S, Rahmanian S, Zeng W, Williams B, Trout D, England W, Chu S, Spitale RC, Tenner A, Wold B, Mortazavi A. A technology-agnostic long-read analysis pipeline for transcriptome discovery and quantification F1000research. 8. DOI: 10.7490/F1000Research.1117633.1  0.265
2022 Javonillo DI, Tran KM, Phan J, Hingco E, Kramár EA, da Cunha C, Forner S, Kawauchi S, Milinkeviciute G, Gomez-Arboledas A, Neumann J, Banh CE, Huynh M, Matheos DP, Rezaie N, ... ... Tenner AJ, et al. Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease. Frontiers in Neuroscience. 15: 785276. PMID 35140584 DOI: 10.3389/fnins.2021.785276  0.264
1999 Ruiz S, Henschen-Edman AH, Nagase H, Tenner AJ. Digestion of C1q collagen-like domain with MMPs-1,-2,-3, and -9 further defines the sequence involved in the stimulation of neutrophil superoxide production Journal of Leukocyte Biology. 66: 416-422. PMID 10496311 DOI: 10.1002/Jlb.66.3.416  0.26
2008 Fraser DA, Tenner AJ. Directing an appropriate immune response: The role of defense collagens and other soluble pattern recognition molecules Current Drug Targets. 9: 113-122. PMID 18288962 DOI: 10.2174/138945008783502476  0.258
2021 Forner S, Kawauchi S, Balderrama-Gutierrez G, Kramár EA, Matheos DP, Phan J, Javonillo DI, Tran KM, Hingco E, da Cunha C, Rezaie N, Alcantara JA, Baglietto-Vargas D, Jansen C, Neumann J, ... ... Tenner AJ, et al. Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease. Scientific Data. 8: 270. PMID 34654824 DOI: 10.1038/s41597-021-01054-y  0.256
2012 Stephan AH, Madison DV, Mateos J, Fraser D, Coutellier L, Lovelett E, Tsai H, Huang E, Rowitch D, Kim L, Tenner A, Shamloo M, Barres BA. A role for C1q in normal brain aging Immunobiology. 217: 1133. DOI: 10.1016/J.Imbio.2012.08.014  0.256
2000 Jack D, Vogel U, Tenner A, Frosch M, Turner M, Klein N. Regulation of the inflammatory response to Nelsseria meningitidis B1940 by mannose-binding lectin Immunopharmacology. 49: 88. DOI: 10.1016/S0162-3109(00)80256-8  0.255
1984 Terkeltaub R, Curtiss LK, Tenner AJ, Ginsberg MH. Lipoproteins containing apoprotein B are a major regulator of neutrophil responses to monosodium urate crystals. The Journal of Clinical Investigation. 73: 1719-30. PMID 6725556 DOI: 10.1172/Jci111380  0.25
2021 Gomez-Arboledas A, Acharya MM, Tenner AJ. The Role of Complement in Synaptic Pruning and Neurodegeneration. Immunotargets and Therapy. 10: 373-386. PMID 34595138 DOI: 10.2147/ITT.S305420  0.249
2008 Im S, Hammond LE, Yousef L, Fraser D, Tenner AJ, Young S, Osborne TF. SREBP‐1a Regulates Cellular Defense Responses in Bone Marrow‐Derived Macrophages The Faseb Journal. 22: 273-273. DOI: 10.1096/Fasebj.22.2_Supplement.273  0.246
2023 Tran KM, Kawauchi S, Kramár EA, Rezaie N, Liang HY, Sakr JS, Gomez-Arboledas A, Arreola MA, Cunha CD, Phan J, Wang S, Collins S, Walker A, Shi KX, Neumann J, ... ... Tenner AJ, et al. A Trem2 mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques. Molecular Neurodegeneration. 18: 12. PMID 36803190 DOI: 10.1186/s13024-023-00598-4  0.237
1993 Tenner AJ. Functional aspects of the C1q receptors Behring Institute Mitteilungen. 241-253. PMID 8172573  0.234
1983 Terkeltaub R, Tenner AJ, Kozin F, Ginsberg MH. Plasma protein binding by monosodium urate crystals. Analysis of two-dimensional gel electrophoresis Arthritis and Rheumatism. 26: 775-783. PMID 6305372 DOI: 10.1002/Art.1780260612  0.232
2024 Garcia-Agudo LF, Shi Z, Smith IF, Kramár EA, Tran K, Kawauchi S, Wang S, Collins S, Walker A, Shi KX, Neumann J, Liang HY, Da Cunha C, Milinkeviciute G, Morabito S, ... ... Tenner AJ, et al. BIN1 suppresses glial response to plaques in mouse model of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38460121 DOI: 10.1002/alz.13767  0.231
2000 Head E, Azizeh BY, Wong SM, Lott IT, Tenner AJ, Cotman CW, Cribbs DH. C1Q and inflammation in Down syndrome pathogenesis Neurobiology of Aging. 21: 12. DOI: 10.1016/S0197-4580(00)82731-1  0.23
1972 Tenner AJ, Wallace RA. A cyclic AMP-stimulated protein kinase from amphibian ovary and oocytes Bba - Enzymology. 276: 416-424. PMID 4341588 DOI: 10.1016/0005-2744(72)91002-9  0.228
2024 Soni N, Hohsfield LA, Tran KM, Kawauchi S, Walker A, Javonillo D, Phan J, Matheos D, Da Cunha C, Uyar A, Milinkeviciute G, Gomez-Arboledas A, Tran K, Kaczorowski CC, Wood MA, ... Tenner AJ, et al. Genetic diversity promotes resilience in a mouse model of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38426371 DOI: 10.1002/alz.13753  0.225
2020 Oblak AL, Forner S, Territo PR, Sasner M, Carter GW, Howell GR, Sukoff-Rizzo SJ, Logsdon BA, Mangravite LM, Mortazavi A, Baglietto-Vargas D, Green KN, MacGregor GR, Wood MA, Tenner AJ, et al. Model organism development and evaluation for late-onset Alzheimer's disease: MODEL-AD. Alzheimer's & Dementia (New York, N. Y.). 6: e12110. PMID 33283040 DOI: 10.1002/trc2.12110  0.223
2020 Vitek MP, Araujo JA, Fossel M, Greenberg BD, Howell GR, Rizzo SJS, Seyfried NT, Tenner AJ, Territo PR, Windisch M, Bain LJ, Ross A, Carrillo MC, Lamb BT, Edelmayer RM. Translational animal models for Alzheimer's disease: An Alzheimer's Association Business Consortium Think Tank. Alzheimer's & Dementia (New York, N. Y.). 6: e12114. PMID 33457489 DOI: 10.1002/trc2.12114  0.222
1987 Bobak DA, Gaither TA, Frank MM, Tenner AJ. Modulation of FcR function by complement: Subcomponent C1q enhances the phagocytosis of IgG-opsonized targets by human monocytes and culture-derived macrophages Journal of Immunology. 138: 1150-1156. PMID 3492544  0.222
2000 Fonseca MI, Carpenter P, Palmarini G, Tenner AJ. Localization of C1qRp in human tissue Immunopharmacology. 49: 17. DOI: 10.1016/S0162-3109(00)80046-6  0.221
2022 Zhang H, Chen L, Johnston KG, Crapser J, Green KN, Ha NM, Tenner AJ, Holmes TC, Nitz DA, Xu X. Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for Alzheimer's disease. Neurobiology of Disease. 176: 105939. PMID 36462718 DOI: 10.1016/j.nbd.2022.105939  0.22
1992 Goodman EB, Tenner AJ. Signal transduction mechanisms of C1q-mediated superoxide production: Evidence for the involvement of temporally distinct staurosporine-insensitive and -sensitive pathways Journal of Immunology. 148: 3920-3928. PMID 1318335  0.22
2018 Tenner AJ, Atkinson JP, Holers VM. Preface to the Special issue for the 27th International complement workshop. Molecular Immunology. PMID 30060927 DOI: 10.1016/J.Molimm.2018.07.010  0.219
1988 Rimoldi MT, Tenner AJ, Bobak DA, Joiner KA. Enhanced invasion of mononuclear phagocytes by serum-treated Trypanosoma cruzi is due to Clq Memorias Do Instituto Oswaldo Cruz. 83: 456-458. PMID 3075688 DOI: 10.1590/S0074-02761988000500046  0.219
2024 Gomez-Arboledas A, Fonseca MI, Kramar E, Chu SH, Schartz ND, Selvan P, Wood MA, Tenner AJ. C5aR1 signaling promotes region- and age-dependent synaptic pruning in models of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38278523 DOI: 10.1002/alz.13682  0.219
2023 Gomez-Arboledas A, Fonseca MI, Kramar E, Chu SH, Schartz N, Selvan P, Wood MA, Tenner AJ. C5aR1 signaling promotes region and age dependent synaptic pruning in models of Alzheimer's Disease. Biorxiv : the Preprint Server For Biology. PMID 37873302 DOI: 10.1101/2023.09.29.560234  0.219
2016 Fujita T, Wakamiya N, Tenner AJ. Preface to the Special Issue for the XXVI International Complement Workshop. Immunobiology. PMID 27402136 DOI: 10.1016/J.Imbio.2016.06.225  0.214
1994 Jiang H, Burdick D, Glabe CG, Cotman CW, Tenner AJ. beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain. Journal of Immunology (Baltimore, Md. : 1950). 152: 5050-9. PMID 8176223  0.21
2024 Butler CA, Mendoza Arvilla A, Milinkeviciute G, Da Cunha C, Kawauchi S, Rezaie N, Liang HY, Javonillo D, Thach A, Wang S, Collins S, Walker A, Shi KX, Neumann J, Gomez-Arboledas A, ... ... Tenner AJ, et al. The Abca7 variant reduces Aβ generation, plaque load, and neuronal damage. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38506634 DOI: 10.1002/alz.13783  0.201
1991 Guan E, Burgess WH, Robinson SL, Goodman EB, McTigue KJ, Tenner AJ. Phagocytic cell molecules that bind the collagen-like region of C1q: Involvement in the C1q-mediated enhancement of phagocytosis Journal of Biological Chemistry. 266: 20345-20355. PMID 1939090  0.196
1998 Nepomuceno RR, Tenner AJ. C1qR(P), the C1q receptor that enhances phagocytosis, is detected specifically in human cells of myeloid lineage, endothelial cells, and platelets Journal of Immunology. 160: 1929-1935. PMID 9469455  0.187
1986 Bobak DA, Frank MM, Tenner AJ. Characterization of C1q receptor expression on human phagocytic cells: Effects of PDBu and fMLP Journal of Immunology. 136: 4604-4610. PMID 3486907  0.181
1994 Guan E, Robinson SL, Goodman EB, Tenner AJ. Cell-surface protein identified on phagocytic cells modulates the C1q- mediated enhancement of phagocytosis Journal of Immunology. 152: 4005-4016. PMID 8144968  0.178
1989 Tenner AJ, Robinson SL, Borchelt J, Wright JR. Human pulmonary surfactant protein (SP-A), a protein structurally homologous to C1q, can enhance FcR- and CR1-mediated phagocytosis Journal of Biological Chemistry. 264: 13923-13928. PMID 2788165  0.169
1991 Young KR, Ambrus JL, Malbran A, Fauci AS, Tenner AJ. Complement subcomponent C1q stimulates Ig production by human B lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 146: 3356-64. PMID 1902854  0.169
2021 Garred P, Tenner AJ, Mollnes TE. Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics. Pharmacological Reviews. 73: 792-827. PMID 33687995 DOI: 10.1124/pharmrev.120.000072  0.156
1981 Tenner AJ, Cooper NR. Identification of types of cells in human peripheral blood that bind C1q. Journal of Immunology (Baltimore, Md. : 1950). 126: 1174-9. PMID 6970220  0.155
2001 Parker CJ, Tenner AJ. Unraveling of mechanisms and discovering novel roles for complement in health and disease International Immunopharmacology. 1: 357-358. DOI: 10.1016/S1567-5769(01)00018-2  0.15
1980 Tenner AJ, Cooper NR. Analysis of receptor-mediated C1q binding to human peripheral blood mononuclear cells. Journal of Immunology (Baltimore, Md. : 1950). 125: 1658-64. PMID 7410850  0.147
1987 Tenner AJ, Frank MM. A sensitive specific hemolytic assay for proenzyme C1 Complement. 4: 42-52. PMID 3552398  0.132
1996 Michalek MT, Melican DT, Brunke-Reese D, Lange Vin M, Tenner AJ, Mackin WM. Activation of human pmns by pgg-glucan (betafectin®) requires crosslinking of a surface receptor Faseb Journal. 10: A1339.  0.13
2021 Gordon MN, Heneka MT, Le Page LM, Limberger C, Morgan D, Tenner AJ, Terrando N, Willette AA, Willette SA. Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34874605 DOI: 10.1002/alz.12488  0.126
1981 Tenner AJ, Lesavre PH, Cooper NR. Purification and radiolabeling of human C1q. Journal of Immunology (Baltimore, Md. : 1950). 127: 648-53. PMID 7252154  0.125
1989 Tenner AJ. C1q interactions with cell surface receptors Behring Institut Mitteilungen. 220-235. PMID 2679535  0.119
1986 Tenner AJ, Volkin DB. Complement subcomponent C1q secreted by cultured human monocytes has subunit structure identical with that of serum C1q Biochemical Journal. 233: 451-458. PMID 3485427  0.117
1986 Tenner AJ, Frank MM. Activator-bound C1 is less susceptible to inactivation by C1 inhibition than is fluid-phase C1 Journal of Immunology. 137: 625-630. PMID 3722818  0.115
1985 Tenner AJ. Fibroblasts but not cultured monocytes derived from a patient with a complete selective deficiency of serum C1q synthesize and secrete C1q activity Federation Proceedings. 44.  0.109
1985 Bohnsack JF, Tenner AJ, Laurie GW. C1q binds to laminin (Lam): A mechanism for deposition and retention of immune complexes in basement membranes (BM) Federation Proceedings. 44.  0.107
1984 Tenner AJ, Ziccardi RJ, Cooper NR. Antibody-independent C1 activation by E. coli. Journal of Immunology (Baltimore, Md. : 1950). 133: 886-91. PMID 6376630  0.107
1982 Tenner AJ, Cooper NR. Stimulation of a human polymorphonuclear leukocyte oxidative response by the C1q subunit of the first complement component. Journal of Immunology (Baltimore, Md. : 1950). 128: 2547-52. PMID 6281333  0.106
2021 Holden SS, Grandi FC, Aboubakr O, Higashikubo B, Cho FS, Chang AH, Forero AO, Morningstar AR, Mathur V, Kuhn LJ, Suri P, Sankaranarayanan S, Andrews-Zwilling Y, Tenner AJ, Luthi A, et al. Complement factor C1q mediates sleep spindle loss and epileptic spikes after mild brain injury. Science (New York, N.Y.). 373: eabj2685. PMID 34516796 DOI: 10.1126/science.abj2685  0.095
1984 Tenner AJ, Volkin DB. Cultured human monocyte synthesize and secrete material with hemolytic activity, immunochemical properties and subunit structure identical to serum C1q Federation Proceedings. 43.  0.094
2021 Cong Q, Soteros BM, Huo A, Li Y, Tenner AJ, Sia GM. C1q and SRPX2 regulate microglia mediated synapse elimination during early development in the visual thalamus but not the visual cortex. Glia. PMID 34762332 DOI: 10.1002/glia.24114  0.093
2000 Eggleton P, Tenner AJ, Reid KBM. C1q receptors Clinical and Experimental Immunology. 120: 406-412. PMID 10844516 DOI: 10.1046/j.1365-2249.2000.01218.x  0.08
2018 Tenner AJ, Atkinson JP, Holers VM. Preface to the Special issue for the 27th International complement workshop. Molecular Immunology. PMID 30060927 DOI: 10.1016/j.molimm.2018.07.010  0.065
2021 Rose C, Nichols T, Hackner D, Chang J, Straube S, Jooste W, Sawe H, Tenner A. Utilizing Lean software development strategies to improve global eHealth initiatives: viewpoint from a basic emergency care app. Jmir Formative Research. PMID 33882013 DOI: 10.2196/14851  0.057
1973 Chrispeels MJ, Tenner AJ, Johnson KD. Synthesis and release of sucrose by the aleurone layer of barley: Regulation by gibberellic acid Planta. 113: 35-46. DOI: 10.1007/Bf00385187  0.039
2019 Jahn HK, Kwan J, O'Reilly G, Geduld H, Douglass K, Tenner A, Wallis L, Tupesis J, Mowafi HO. Towards developing a consensus assessment framework for global emergency medicine fellowships. Bmc Emergency Medicine. 19: 68. PMID 31711428 DOI: 10.1186/s12873-019-0286-6  0.038
2023 Berger D, Wong-Castillo J, Seymour R, Colwell C, Tenner A, Brown J, Mercer M. FEASIBILITY AND SAFETY OF A FIELD CARE CLINIC AS AN ALTERNATIVE AMBULANCE DESTINATION DURING THE COVID-19 PANDEMIC. International Journal of Paramedicine. 1: 73-84. PMID 37009632 DOI: 10.56068/ampo6844  0.032
2020 Straube S, Chang-Bullick J, Nicholaus P, Mfinanga J, Rose C, Nichols T, Hackner D, Murphy S, Sawe H, Tenner A. Novel educational adjuncts for the World Health Organization Basic Emergency Care Course: A prospective cohort study. African Journal of Emergency Medicine : Revue Africaine De La Medecine D'Urgence. 10: 30-34. PMID 32161709 DOI: 10.1016/j.afjem.2019.11.003  0.03
2011 Kessler CS, Bhandarkar S, Casey P, Tenner A. Predicting patient patterns in veterans administration emergency departments. The Western Journal of Emergency Medicine. 12: 204-7. PMID 21691527  0.015
1994 Busse WW, Tenner AJ. Book review Journal of Clinical Immunology. 14: 212-214. DOI: 10.1007/BF01533370  0.01
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