Lawrence Reagan, PhD - Publications

Affiliations: 
Pharmacology, Physiology, & Neuroscience University of South Carolina, Columbia, SC 
Area:
hippocampus, stress, amygdala, diabetes, glucose, learning and memory

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Erichsen JM, Fadel JR, Reagan LP. Peripheral versus central insulin and leptin resistance: Role in metabolic disorders, cognition, and neuropsychiatric diseases. Neuropharmacology. 203: 108877. PMID 34762922 DOI: 10.1016/j.neuropharm.2021.108877  0.572
2021 Erichsen JM, Calva CB, Reagan LP, Fadel JR. Intranasal insulin and orexins to treat age-related cognitive decline. Physiology & Behavior. 113370. PMID 33621561 DOI: 10.1016/j.physbeh.2021.113370  0.558
2019 Hill MN, Hunter R, Reagan LP. Editorial: A brief overview of the 2018 Neurobiology of Stress Workshop. Neurobiology of Stress. 11: 100193. PMID 31467946 DOI: 10.1016/J.Ynstr.2019.100193  0.698
2019 Grillo CA, Woodruff J, Macht VA, Reagan LP. Insulin resistance and hippocampal dysfunction: Disentangling peripheral and brain causes from consequences. Experimental Neurology. PMID 31028829 DOI: 10.1016/j.expneurol.2019.04.012  0.746
2019 Macht VA, Woodruff JL, Maissy ES, Grillo CA, Wilson MA, Fadel JR, Reagan LP. Pyridostigmine bromide and stress interact to impact immune function, cholinergic neurochemistry and behavior in a rat model of Gulf War Illness. Brain, Behavior, and Immunity. PMID 30953774 DOI: 10.1016/J.Bbi.2019.04.015  0.765
2018 Macht VA, Woodruff JL, Grillo CA, Wood CS, Wilson MA, Reagan LP. Pathophysiology in a model of Gulf War Illness: Contributions of pyridostigmine bromide and stress. Psychoneuroendocrinology. 96: 195-202. PMID 30041099 DOI: 10.1016/j.psyneuen.2018.07.015  0.77
2017 Macht VA, Reagan LP. Chronic stress from adolescence to aging in the prefrontal cortex: A neuroimmune perspective. Frontiers in Neuroendocrinology. PMID 29258741 DOI: 10.1016/j.yfrne.2017.12.001  0.763
2017 Van Doorn C, Macht VA, Grillo CA, Reagan LP. Leptin resistance and hippocampal behavioral deficits. Physiology & Behavior. PMID 28267584 DOI: 10.1016/j.physbeh.2017.03.002  0.765
2016 Macht VA, Vazquez M, Petyak C, Grillo CA, Kaigler K, Enos RT, McClellan JL, Cranford TL, Murphy EA, Nyland JF, Solomon G, Gertler A, Wilson MA, Reagan LP. Leptin resistance elicts depressive-like behaviors in rats. Brain, Behavior, and Immunity. PMID 27743935 DOI: 10.1016/J.Bbi.2016.10.008  0.739
2016 Fadel JR, Reagan LP. Stop signs in hippocampal insulin signaling: the role of insulin resistance in structural, functional and behavioral deficits. Current Opinion in Behavioral Sciences. 9: 47-54. PMID 26955646 DOI: 10.1016/J.Cobeha.2015.12.004  0.586
2016 Fadel JR, Reagan LP. Stop signs in hippocampal insulin signaling: The role of insulin resistance in structural, functional and behavioral deficits Current Opinion in Behavioral Sciences. 9: 47-54. DOI: 10.1016/j.cobeha.2015.12.004  0.556
2015 Wilson MA, Grillo CA, Fadel JR, Reagan LP. Stress as a one-armed bandit: Differential effects of stress paradigms on the morphology, neurochemistry and behavior in the rodent amygdala. Neurobiology of Stress. 1: 195-208. PMID 26844236 DOI: 10.1016/J.Ynstr.2015.06.001  0.635
2015 Grillo CA, Piroli GG, Lawrence RC, Wrighten SA, Green AJ, Wilson SP, Sakai RR, Kelly SJ, Wilson MA, Mott DD, Reagan LP. Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity. Diabetes. PMID 26216852 DOI: 10.2337/Db15-0596  0.781
2015 Grillo CA, Risher M, Macht VA, Bumgardner AL, Hang A, Gabriel C, Mocaër E, Piroli GG, Fadel JR, Reagan LP. Repeated restraint stress-induced atrophy of glutamatergic pyramidal neurons and decreases in glutamatergic efflux in the rat amygdala are prevented by the antidepressant agomelatine. Neuroscience. 284: 430-43. PMID 25280788 DOI: 10.1016/J.Neuroscience.2014.09.047  0.82
2015 Wilson MA, Grillo CA, Fadel JR, Reagan LP. Stress as a one-armed bandit: Differential effects of stress paradigms on the morphology, neurochemistry and behavior in the rodent amygdala Neurobiology of Stress. 1: 195-208. DOI: 10.1016/j.ynstr.2015.06.001  0.604
2014 Grillo CA, Mulder P, Macht VA, Kaigler KF, Wilson SP, Wilson MA, Reagan LP. Dietary restriction reverses obesity-induced anhedonia. Physiology & Behavior. 128: 126-32. PMID 24518861 DOI: 10.1016/J.Physbeh.2014.01.026  0.744
2013 Fadel JR, Jolivalt CG, Reagan LP. Food for thought: the role of appetitive peptides in age-related cognitive decline. Ageing Research Reviews. 12: 764-76. PMID 23416469 DOI: 10.1016/J.Arr.2013.01.009  0.577
2013 Piroli GG, Reznikov LR, Grillo CA, Hagar JM, Fadel JR, Reagan LP. Tianeptine modulates amygdalar glutamate neurochemistry and synaptic proteins in rats subjected to repeated stress. Experimental Neurology. 241: 184-93. PMID 23262120 DOI: 10.1016/J.Expneurol.2012.12.005  0.79
2012 Reagan LP, Reznikov LR, Evans AN, Gabriel C, Mocaër E, Fadel JR. The antidepressant agomelatine inhibits stress-mediated changes in amino acid efflux in the rat hippocampus and amygdala. Brain Research. 1466: 91-8. PMID 22647752 DOI: 10.1016/J.Brainres.2012.05.039  0.767
2011 Krause EG, de Kloet AD, Scott KA, Flak JN, Jones K, Smeltzer MD, Ulrich-Lai YM, Woods SC, Wilson SP, Reagan LP, Herman JP, Sakai RR. Blood-borne angiotensin II acts in the brain to influence behavioral and endocrine responses to psychogenic stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15009-15. PMID 22016534 DOI: 10.1523/Jneurosci.0892-11.2011  0.566
2011 Tamashiro KL, Sakai RR, Shively CA, Karatsoreos IN, Reagan LP. Chronic stress, metabolism, and metabolic syndrome. Stress (Amsterdam, Netherlands). 14: 468-74. PMID 21848434 DOI: 10.3109/10253890.2011.606341  0.702
2011 Paranjape SA, Chan O, Zhu W, Horblitt AM, Grillo CA, Wilson S, Reagan L, Sherwin RS. Chronic reduction of insulin receptors in the ventromedial hypothalamus produces glucose intolerance and islet dysfunction in the absence of weight gain. American Journal of Physiology. Endocrinology and Metabolism. 301: E978-83. PMID 21828334 DOI: 10.1152/Ajpendo.00304.2011  0.378
2011 Grillo CA, Piroli GG, Kaigler KF, Wilson SP, Wilson MA, Reagan LP. Downregulation of hypothalamic insulin receptor expression elicits depressive-like behaviors in rats. Behavioural Brain Research. 222: 230-5. PMID 21458499 DOI: 10.1016/J.Bbr.2011.03.052  0.327
2011 Grillo CA, Piroli GG, Junor L, Wilson SP, Mott DD, Wilson MA, Reagan LP. Obesity/hyperleptinemic phenotype impairs structural and functional plasticity in the rat hippocampus. Physiology & Behavior. 105: 138-44. PMID 21354191 DOI: 10.1016/J.Physbeh.2011.02.028  0.311
2011 Grillo CA, Piroli GG, Evans AN, Macht VA, Wilson SP, Scott KA, Sakai RR, Mott DD, Reagan LP. Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction. Physiology & Behavior. 104: 235-41. PMID 21036186 DOI: 10.1016/J.Physbeh.2010.10.020  0.784
2010 McEwen BS, Chattarji S, Diamond DM, Jay TM, Reagan LP, Svenningsson P, Fuchs E. The neurobiological properties of tianeptine (Stablon): from monoamine hypothesis to glutamatergic modulation. Molecular Psychiatry. 15: 237-49. PMID 19704408 DOI: 10.1038/Mp.2009.80  0.331
2009 Grillo CA, Piroli GG, Hendry RM, Reagan LP. Insulin-stimulated translocation of GLUT4 to the plasma membrane in rat hippocampus is PI3-kinase dependent. Brain Research. 1296: 35-45. PMID 19679110 DOI: 10.1016/j.brainres.2009.08.005  0.589
2009 Reznikov LR, Reagan LP, Fadel JR. Effects of acute and repeated restraint stress on GABA efflux in the rat basolateral and central amygdala. Brain Research. 1256: 61-8. PMID 19124010 DOI: 10.1016/J.Brainres.2008.12.022  0.752
2009 Wrighten SA, Piroli GG, Grillo CA, Reagan LP. A look inside the diabetic brain: Contributors to diabetes-induced brain aging. Biochimica Et Biophysica Acta. 1792: 444-53. PMID 19022375 DOI: 10.1016/J.Bbadis.2008.10.013  0.749
2009 Kelly SJ, Bernard K, Muñoz C, Lawrence RC, Thacker J, Grillo CA, Piroli GG, Reagan LP. Effects of the AMPA receptor modulator S 18986 on measures of cognition and oxidative stress in aged rats. Psychopharmacology. 202: 225-35. PMID 18762915 DOI: 10.1007/s00213-008-1301-x  0.521
2008 Reagan LP, Grillo CA, Piroli GG. The As and Ds of stress: metabolic, morphological and behavioral consequences. European Journal of Pharmacology. 585: 64-75. PMID 18387603 DOI: 10.1016/j.ejphar.2008.02.050  0.37
2008 Reznikov LR, Reagan LP, Fadel JR. Activation of phenotypically distinct neuronal subpopulations in the anterior subdivision of the rat basolateral amygdala following acute and repeated stress. The Journal of Comparative Neurology. 508: 458-72. PMID 18335544 DOI: 10.1002/Cne.21687  0.749
2007 Reagan LP. Insulin signaling effects on memory and mood. Current Opinion in Pharmacology. 7: 633-7. PMID 18023616 DOI: 10.1016/j.coph.2007.10.012  0.311
2007 Grillo CA, Tamashiro KL, Piroli GG, Melhorn S, Gass JT, Newsom RJ, Reznikov LR, Smith A, Wilson SP, Sakai RR, Reagan LP. Lentivirus-mediated downregulation of hypothalamic insulin receptor expression. Physiology & Behavior. 92: 691-701. PMID 17585961 DOI: 10.1016/J.Physbeh.2007.05.043  0.735
2007 Reznikov LR, Grillo CA, Piroli GG, Pasumarthi RK, Reagan LP, Fadel J. Acute stress-mediated increases in extracellular glutamate levels in the rat amygdala: differential effects of antidepressant treatment. The European Journal of Neuroscience. 25: 3109-14. PMID 17561824 DOI: 10.1111/J.1460-9568.2007.05560.X  0.777
2007 Piroli GG, Grillo CA, Reznikov LR, Adams S, McEwen BS, Charron MJ, Reagan LP. Corticosterone impairs insulin-stimulated translocation of GLUT4 in the rat hippocampus. Neuroendocrinology. 85: 71-80. PMID 17426391 DOI: 10.1159/000101694  0.734
2007 Reagan LP, Hendry RM, Reznikov LR, Piroli GG, Wood GE, McEwen BS, Grillo CA. Tianeptine increases brain-derived neurotrophic factor expression in the rat amygdala. European Journal of Pharmacology. 565: 68-75. PMID 17368617 DOI: 10.1016/J.Ejphar.2007.02.023  0.788
2007 Piroli GG, Grillo CA, Reznikov LR, Reagan LP. Expression and functional activities of glucose transporters in the central nervous system Handbook of Neurochemistry and Molecular Neurobiology: Neural Membranes and Transport. 387-404. DOI: 10.1007/978-0-387-30380-2_19  0.643
2006 Autry AE, Grillo CA, Piroli GG, Rothstein JD, McEwen BS, Reagan LP. Glucocorticoid regulation of GLT-1 glutamate transporter isoform expression in the rat hippocampus. Neuroendocrinology. 83: 371-9. PMID 17028421 DOI: 10.1159/000096092  0.469
2005 Winocur G, Greenwood CE, Piroli GG, Grillo CA, Reznikov LR, Reagan LP, McEwen BS. Memory impairment in obese Zucker rats: an investigation of cognitive function in an animal model of insulin resistance and obesity. Behavioral Neuroscience. 119: 1389-95. PMID 16300445 DOI: 10.1037/0735-7044.119.5.1389  0.713
2005 Grillo CA, Piroli GG, Wood GE, Reznikov LR, McEwen BS, Reagan LP. Immunocytochemical analysis of synaptic proteins provides new insights into diabetes-mediated plasticity in the rat hippocampus. Neuroscience. 136: 477-86. PMID 16226381 DOI: 10.1016/J.Neuroscience.2005.08.019  0.71
2004 McEwen BS, Reagan LP. Glucose transporter expression in the central nervous system: relationship to synaptic function. European Journal of Pharmacology. 490: 13-24. PMID 15094070 DOI: 10.1016/j.ejphar.2004.02.041  0.4
2004 Piroli GG, Grillo CA, Charron MJ, McEwen BS, Reagan LP. Biphasic effects of stress upon GLUT8 glucose transporter expression and trafficking in the diabetic rat hippocampus. Brain Research. 1006: 28-35. PMID 15047021 DOI: 10.1016/J.Brainres.2004.01.044  0.541
2004 Wood GE, Young LT, Reagan LP, Chen B, McEwen BS. Stress-induced structural remodeling in hippocampus: prevention by lithium treatment. Proceedings of the National Academy of Sciences of the United States of America. 101: 3973-8. PMID 15001711 DOI: 10.1073/pnas.0400208101  0.498
2004 Reagan LP, Rosell DR, Wood GE, Spedding M, Muñoz C, Rothstein J, McEwen BS. Chronic restraint stress up-regulates GLT-1 mRNA and protein expression in the rat hippocampus: reversal by tianeptine. Proceedings of the National Academy of Sciences of the United States of America. 101: 2179-84. PMID 14766991 DOI: 10.1073/pnas.0307294101  0.494
2003 Grillo CA, Piroli GG, Rosell DR, Hoskin EK, Mcewen BS, Reagan LP. Region specific increases in oxidative stress and superoxide dismutase in the hippocampus of diabetic rats subjected to stress. Neuroscience. 121: 133-40. PMID 12946706 DOI: 10.1016/S0306-4522(03)00343-9  0.485
2003 Wood GE, Young LT, Reagan LP, McEwen BS. Acute and chronic restraint stress alter the incidence of social conflict in male rats. Hormones and Behavior. 43: 205-13. PMID 12614651 DOI: 10.1016/S0018-506X(02)00026-0  0.497
2003 Lucas LR, Reagan LP, Akama KT, Ma LY, Tamashiro KL, Sakai RR, McEwen BS. Decreases in neurokinin-3 tachykinin receptor-immunoreactive and -mRNA levels are associated with salt appetite in the deoxycorticosterone-treated rat. Brain Research. 960: 252-8. PMID 12505679 DOI: 10.1016/S0006-8993(02)03908-2  0.769
2002 McEwen BS, Magarinos AM, Reagan LP. Structural plasticity and tianeptine: cellular and molecular targets. European Psychiatry : the Journal of the Association of European Psychiatrists. 17: 318-30. PMID 15177088 DOI: 10.1016/S0924-9338(02)00650-8  0.506
2002 Reagan LP, McEwen BS. Diabetes, but not stress, reduces neuronal nitric oxide synthase expression in rat hippocampus: implications for hippocampal synaptic plasticity. Neuroreport. 13: 1801-4. PMID 12395127 DOI: 10.1097/00001756-200210070-00022  0.523
2002 McEwen BS, Magariños AM, Reagan LP. Studies of hormone action in the hippocampal formation: possible relevance to depression and diabetes. Journal of Psychosomatic Research. 53: 883-90. PMID 12377298 DOI: 10.1016/S0022-3999(02)00307-0  0.468
2002 Piroli GG, Grillo CA, Hoskin EK, Znamensky V, Katz EB, Milner TA, McEwen BS, Charron MJ, Reagan LP. Peripheral glucose administration stimulates the translocation of GLUT8 glucose transporter to the endoplasmic reticulum in the rat hippocampus. The Journal of Comparative Neurology. 452: 103-14. PMID 12271485 DOI: 10.1002/Cne.10368  0.432
2002 Reagan LP, Rosell DR, Alves SE, Hoskin EK, McCall AL, Charron MJ, McEwen BS. GLUT8 glucose transporter is localized to excitatory and inhibitory neurons in the rat hippocampus. Brain Research. 932: 129-34. PMID 11911870 DOI: 10.1016/S0006-8993(02)02308-9  0.396
2001 Magariños AM, Jain K, Blount ED, Reagan L, Smith BH, McEwen BS. Peritoneal implantation of macroencapsulated porcine pancreatic islets in diabetic rats ameliorates severe hyperglycemia and prevents retraction and simplification of hippocampal dendrites. Brain Research. 902: 282-7. PMID 11384623 DOI: 10.1016/S0006-8993(01)02400-3  0.525
2001 Reagan LP, Gorovits N, Hoskin EK, Alves SE, Katz EB, Grillo CA, Piroli GG, McEwen BS, Charron MJ. Localization and regulation of GLUTx1 glucose transporter in the hippocampus of streptozotocin diabetic rats. Proceedings of the National Academy of Sciences of the United States of America. 98: 2820-5. PMID 11226324 DOI: 10.1073/Pnas.051629798  0.455
2001 Milner TA, McEwen BS, Hayashi S, Li CJ, Reagan LP, Alves SE. Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites. The Journal of Comparative Neurology. 429: 355-71. PMID 11116225 DOI: 10.1002/1096-9861(20010115)429:3<355::AID-CNE1>3.0.CO;2  0.36
2000 Reagan LP, Magariños AM, Yee DK, Swzeda LI, Van Bueren A, McCall AL, McEwen BS. Oxidative stress and HNE conjugation of GLUT3 are increased in the hippocampus of diabetic rats subjected to stress. Brain Research. 862: 292-300. PMID 10799703 DOI: 10.1016/S0006-8993(00)02212-5  0.519
1999 Reagan LP, Magariños AM, Lucas LR, van Bueren A, McCall AL, McEwen BS. Regulation of GLUT-3 glucose transporter in the hippocampus of diabetic rats subjected to stress. American Journal of Physiology. Endocrinology and Metabolism. 276: E879-E886. PMID 29590819 DOI: 10.1152/ajpendo.1999.276.5.E879  0.737
1999 Reagan LP, Magariños AM, McEwen BS. Neurological changes induced by stress in streptozotocin diabetic rats. Annals of the New York Academy of Sciences. 893: 126-37. PMID 10672234 DOI: 10.1111/J.1749-6632.1999.Tb07822.X  0.552
1999 Reagan LP, McKittrick CR, McEwen BS. Corticosterone and phenytoin reduce neuronal nitric oxide synthase messenger RNA expression in rat hippocampus. Neuroscience. 91: 211-9. PMID 10336072 DOI: 10.1016/S0306-4522(98)00615-0  0.445
1999 Reagan LP, Magariños AM, Lucas LR, van Bueren A, McCall AL, McEwen BS. Regulation of GLUT-3 glucose transporter in the hippocampus of diabetic rats subjected to stress. The American Journal of Physiology. 276: E879-86. PMID 10329982 DOI: 10.1152/Ajpendo.1999.276.5.E879  0.737
1998 Shelat SG, Reagan LP, King JL, Fluharty SJ, Flanagan-Cato LM. Analysis of angiotensin type 2 receptors in vasopressinergic neurons and pituitary in the rat. Regulatory Peptides. 73: 103-12. PMID 9533814 DOI: 10.1016/S0167-0115(97)01066-5  0.663
1997 Reagan LP, McEwen BS. Controversies surrounding glucocorticoid-mediated cell death in the hippocampus. Journal of Chemical Neuroanatomy. 13: 149-67. PMID 9315966 DOI: 10.1016/S0891-0618(97)00031-8  0.409
1996 Reagan LP, Sakai RR, Fluharty SJ. Immunological analysis of angiotensin AT2 receptors in peripheral tissues of neonatal and adult rats. Regulatory Peptides. 65: 159-64. PMID 8884984 DOI: 10.1016/S0167-0115(96)00087-0  0.468
1994 Reagan LP, Flanagan-Cato LM, Yee DK, Ma LY, Sakai RR, Fluharty SJ. Immunohistochemical mapping of angiotensin type 2 (AT2) receptors in rat brain. Brain Research. 662: 45-59. PMID 7859090 DOI: 10.1016/0006-8993(94)90794-3  0.721
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