Robert T. Schimke - Related publications

Biological Sciences Stanford University, Palo Alto, CA 
protein turnover and gene amplification
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Zhang L, Huang R, Lu L, Fu R, Guo G, Gu Y, Liu Z, He L, Malissen M, Liang Y. Gene Knock-in by CRISPR/Cas9 and Cell Sorting in Macrophage and T Cell Lines. Journal of Visualized Experiments : Jove. PMID 34842230 DOI: 10.3791/62328   
2021 Kim KL, van Galen P, Hovestadt V, Rahme GJ, Andreishcheva EN, Shinde A, Gaskell E, Jones DR, Shema E, Bernstein BE. Systematic detection of mA-modified transcripts at single-molecule and single-cell resolution. Cell Reports Methods. 1. PMID 34734208 DOI: 10.1016/j.crmeth.2021.100061   
2021 Loo J, Sicher I, Goff A, Kim O, Clary N, Alexeev A, Sulchek T, Zamarayeva A, Han S, Calero-Garcia M. Microfluidic transfection of mRNA into human primary lymphocytes and hematopoietic stem and progenitor cells using ultra-fast physical deformations. Scientific Reports. 11: 21407. PMID 34725429 DOI: 10.1038/s41598-021-00893-4   
2021 Wu X, Yang Y, Zhong C, Wang T, Deng Y, Huang H, Lin H, Meng Z, Liu X. Single-Cell Atlas of Adult Testis in Protogynous Hermaphroditic Orange-Spotted Grouper, . International Journal of Molecular Sciences. 22. PMID 34830486 DOI: 10.3390/ijms222212607   
2021 Booeshaghi AS, Yao Z, van Velthoven C, Smith K, Tasic B, Zeng H, Pachter L. Isoform cell-type specificity in the mouse primary motor cortex. Nature. 598: 195-199. PMID 34616073 DOI: 10.1038/s41586-021-03969-3   
2021 Shen J, Shi H, Zhao Y, Fent K, Zhang K. Large-Scale Transcriptional Profiling of Molecular Perturbations Reveals Cell Line Specific Responses and Implications for Environmental Screening. Environmental Science & Technology. PMID 34714046 DOI: 10.1021/acs.est.1c04965   
2021 Kronenberg J, Schrödter K, Noll GA, Twyman RM, Prüfer D, Känel P. The tobacco phosphatidylethanolamine-binding protein NtFT4 simultaneously improves vitality, growth, and protein yield in human cells. Biotechnology and Bioengineering. 118: 3770-3786. PMID 34110007 DOI: 10.1002/bit.27853   
2021 Nakasone H, Kusuda M, Terasako-Saito K, Kawamura K, Akahoshi Y, Kawamura M, Takeshita J, Kawamura S, Yoshino N, Yoshimura K, Misaki Y, Gomyo A, Kameda K, Tamaki M, Tanihara A, et al. Features of repertoire diversity and gene expression in human cytotoxic T cells following allogeneic hematopoietic cell transplantation. Communications Biology. 4: 1177. PMID 34635773 DOI: 10.1038/s42003-021-02709-7   
2021 Ganguly S, Roy S, Goodwin AP, Cha JN. Generation of 3D cellular spheroids using DNA modified cell receptors and programmable DNA interactions. Biomaterials Science. PMID 34694305 DOI: 10.1039/d1bm01193f   
2021 Jadav A, Truong K. Creation of a synthesis-friendly inflammation-inducible promoter suitable for cell therapy. Integrative Biology : Quantitative Biosciences From Nano to Macro. 13: 230-236. PMID 34632498 DOI: 10.1093/intbio/zyab015   
2021 Raes L, Pille M, Harizaj A, Goetgeluk G, Van Hoeck J, Stremersch S, Fraire JC, Brans T, de Jong OG, Maas-Bakker R, Mastrobattista E, Vader P, De Smedt SC, Vandekerckhove B, Raemdonck K, et al. Cas9 RNP transfection by vapor nanobubble photoporation for cell engineering. Molecular Therapy. Nucleic Acids. 25: 696-707. PMID 34589287 DOI: 10.1016/j.omtn.2021.08.014   
2021 Tsai TH, Lieu AS, Huang TY, Kwan AL, Lin CL, Hsu YC. RTA404, an Activator of Nrf2, Activates the Checkpoint Kinases and Induces Apoptosis through Intrinsic Apoptotic Pathway in Malignant Glioma. Journal of Clinical Medicine. 10. PMID 34768325 DOI: 10.3390/jcm10214805   
2021 Charitidis FT, Adabi E, Thalheimer FB, Clarke C, Buchholz CJ. Monitoring CAR T cell generation with a CD8-targeted lentiviral vector by single-cell transcriptomics. Molecular Therapy. Methods & Clinical Development. 23: 359-369. PMID 34729382 DOI: 10.1016/j.omtm.2021.09.019   
2021 Asada K, Takasawa K, Machino H, Takahashi S, Shinkai N, Bolatkan A, Kobayashi K, Komatsu M, Kaneko S, Okamoto K, Hamamoto R. Single-Cell Analysis Using Machine Learning Techniques and Its Application to Medical Research. Biomedicines. 9. PMID 34829742 DOI: 10.3390/biomedicines9111513   
2021 Yi E, Gujar AD, Guthrie M, Kim H, Zhao D, Johnson KC, Amin SB, Costa ML, Yu Q, Das S, Jillette N, Clow PA, Cheng AW, Verhaak RG. Live-cell imaging shows uneven segregation of extrachromosomal DNA elements and transcriptionally active extrachromosomal DNA hubs in cancer. Cancer Discovery. PMID 34819316 DOI: 10.1158/2159-8290.CD-21-1376   
2021 Riss TL, Moravec RA, Duellman SJ, Niles AL. Treating Cells as Reagents to Design Reproducible Assays. Slas Discovery : Advancing Life Sciences R & D. 24725552211039754. PMID 34530643 DOI: 10.1177/24725552211039754   
2021 Liu Y, Li H, Czajkowsky DM, Shao Z. Monocytic THP-1 cells diverge significantly from their primary counterparts: a comparative examination of the chromosomal conformations and transcriptomes. Hereditas. 158: 43. PMID 34740370 DOI: 10.1186/s41065-021-00205-w   
2021 Medina I, Calleja M, Morata G. Tumorigenesis and cell competition in in the absence of function. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34702735 DOI: 10.1073/pnas.2110062118   
2021 Bakken TE, Jorstad NL, Hu Q, Lake BB, Tian W, Kalmbach BE, Crow M, Hodge RD, Krienen FM, Sorensen SA, Eggermont J, Yao Z, Aevermann BD, Aldridge AI, Bartlett A, et al. Comparative cellular analysis of motor cortex in human, marmoset and mouse. Nature. 598: 111-119. PMID 34616062 DOI: 10.1038/s41586-021-03465-8   
2021 Chen Z, Liu S, Liu W, Jiang P, Wang L, Li J, Zhou H, Guo T. Zinc(II)-Cyclen Multifunctional Complex Module-Mediated Polycation-Based High-Performance pDNA Vectors. Acs Biomaterials Science & Engineering. PMID 34847318 DOI: 10.1021/acsbiomaterials.1c01115   
2021 Chen N, Wu H, Deng Z, Liao Z, Feng S, Luo Z, Chu Y, Qiu G, Li X, Jin Y, Rong S, Wang F, Gan L, Chen R, Zhao L. [An optimized protocol of meniscus cell extraction for single-cell RNA sequencing]. Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University. 41: 1310-1318. PMID 34658344 DOI: 10.12122/j.issn.1673-4254.2021.09.04   
2021 La T, Chen S, Guo T, Zhao XH, Teng L, Li D, Carnell M, Zhang YY, Feng YC, Cole N, Brown AC, Zhang D, Dong Q, Wang JY, Cao H, et al. Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells. Theranostics. 11: 9605-9622. PMID 34646389 DOI: 10.7150/thno.63763   
2021 Mallucci L, Wells V. Intrinsic S phase checkpoint enforced by an antiproliferative oncosuppressor cytokine. Cancer Gene Therapy. PMID 34737438 DOI: 10.1038/s41417-021-00397-3   
2021 Ahmed M, Lai TH, Kim DR. A Small Fraction of Progenitors Differentiate Into Mature Adipocytes by Escaping the Constraints on the Cell Structure. Frontiers in Cell and Developmental Biology. 9: 753042. PMID 34708046 DOI: 10.3389/fcell.2021.753042   
2021 Ghelli Luserna Di Rorà A, Ghetti M, Ledda L, Ferrari A, Bocconcelli M, Padella A, Napolitano R, Fontana MC, Liverani C, Imbrogno E, Bochicchio MT, Paganelli M, Robustelli V, Sanogo S, Cerchione C, et al. Exploring the ATR-CHK1 pathway in the response of doxorubicin-induced DNA damages in acute lymphoblastic leukemia cells. Cell Biology and Toxicology. PMID 34519926 DOI: 10.1007/s10565-021-09640-x   
2021 Wang C, Ma Y, Pei Z, Song F, Zhong J, Wang Y, Yan X, Dai P, Jiang Y, Qiu J, Shi M, Wu X. Sheathless acoustic based flow cell sorter for enrichment of rare cells. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 34806837 DOI: 10.1002/cyto.a.24521   
2021 Shen Y, Jiang L, Iyer VS, Raposo B, Dubnovitsky A, Boddul SV, Kasza Z, Wermeling F. A rapid CRISPR competitive assay for and discovery of potential drug targets affecting the hematopoietic system. Computational and Structural Biotechnology Journal. 19: 5360-5370. PMID 34745454 DOI: 10.1016/j.csbj.2021.09.020   
2021 Papadogianni G, Ravens I, Hassan A, Dittrich-Breiholz O, Bernhardt G, Georgiev H. The impact of stress on the transcriptomic signature of iNKT1 cells. Biochemistry and Biophysics Reports. 28: 101163. PMID 34765746 DOI: 10.1016/j.bbrep.2021.101163   
2021 Chen H, Lv Y, Yin X, Chen X, Chu Q, Zhu QH, Fan L, Guo L. Effects of Sample Size on Plant Single-Cell RNA Profiling. Current Issues in Molecular Biology. 43: 1685-1697. PMID 34698115 DOI: 10.3390/cimb43030119   
2021 Tuzlak S, Dejean AS, Iannacone M, Quintana FJ, Waisman A, Ginhoux F, Korn T, Becher B. Repositioning T cell polarization from single cytokines to complex help. Nature Immunology. 22: 1210-1217. PMID 34545250 DOI: 10.1038/s41590-021-01009-w   
2021 Oh S, Park H, Zhang X. Hybrid Clustering of Single-Cell Gene Expression and Spatial Information Integrated NMF and K-Means. Frontiers in Genetics. 12: 763263. PMID 34819947 DOI: 10.3389/fgene.2021.763263   
2021 Yao C, Zhu C, Tang J, Ou J, Zhang R, Yang D. T Lymphocyte-Captured DNA Network for Localized Immunotherapy. Journal of the American Chemical Society. PMID 34780151 DOI: 10.1021/jacs.1c07036   
2021 Almutairi B, Ali D, Yaseen KN, Alothman NS, Alyami N, Almukhlafi H, Alakhtani S, Alarifi S. Mechanisms of Apoptotic Cell Death by Stainless Steel Nanoparticle Through Reactive Oxygen Species and Caspase-3 Activities on Human Liver Cells. Frontiers in Molecular Biosciences. 8: 729590. PMID 34631797 DOI: 10.3389/fmolb.2021.729590   
2021 Cable J, Elowitz MB, Domingos AI, Habib N, Itzkovitz S, Hamidzada H, Balzer MS, Yanai I, Liberali P, Whited J, Streets A, Cai L, Stergachis AB, Hong CKY, Keren L, et al. Single cell biology-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 34605044 DOI: 10.1111/nyas.14692   
2021 Zhuang Q, Li H, Peng B, Liu Y, Zhang Y, Cai H, Liu S, Ming Y. Single-Cell Transcriptomic Analysis of Peripheral Blood Reveals a Novel B-Cell Subset in Renal Allograft Recipients With Accommodation. Frontiers in Pharmacology. 12: 706580. PMID 34658852 DOI: 10.3389/fphar.2021.706580   
2021 Adil MS, Khulood D, Narayanan SP, Somanath PR. Bioinformatics analyses reveal cell-barrier junction modulations in lung epithelial cells on SARS-CoV-2 infection. Tissue Barriers. 2000300. PMID 34740309 DOI: 10.1080/21688370.2021.2000300   
2021 Yang T, Alessandri-Haber N, Fury W, Schaner M, Breese R, LaCroix-Fralish M, Kim J, Adler C, Macdonald LE, Atwal GS, Bai Y. AdRoit is an accurate and robust method to infer complex transcriptome composition. Communications Biology. 4: 1218. PMID 34686758 DOI: 10.1038/s42003-021-02739-1   
2021 Figueroa MG, Parker LM, Krol K, Zhao M. Distal Promoter-Driven Cre Shows Cell Type-Specific Function in Innate-like T Cells. Immunohorizons. 5: 772-781. PMID 34583938 DOI: 10.4049/immunohorizons.2100079   
2021 Zhang J, Wang H, Wu H, Qiang G. The Functionalities and Clinical Significance of Tumor-Infiltrating Immune Cells in Esophageal Squamous Cell Carcinoma. Biomed Research International. 2021: 8635381. PMID 34616847 DOI: 10.1155/2021/8635381   
2021 Delaloy C, Schuh W, Jäck HM, Bonaud A, Espéli M. Single cell resolution of Plasma Cell fate programming in health and disease. European Journal of Immunology. PMID 34694625 DOI: 10.1002/eji.202149216   
2021 Master A, Huang W, Huang L, Li W, Saglam S, Honkanen R, Rigas B. Simplified ex-vivo drug evaluation in ocular surface cells: Culture on cellulose filters of cells obtained by impression cytology. Experimental Eye Research. 213: 108827. PMID 34742691 DOI: 10.1016/j.exer.2021.108827   
2021 Windels E, Van den Bergh B, Michiels J. Enrichment of Persister Cells Through Β-Lactam-Induced Filamentation and Size Separation. Methods in Molecular Biology (Clifton, N.J.). 2357: 63-69. PMID 34590251 DOI: 10.1007/978-1-0716-1621-5_4   
2021 Liu J, Niu N, Li X, Zhang X, Sood AK. The life cycle of polyploid giant cancer cell and dormancy in cancer: opportunities for novel therapeutic interventions. Seminars in Cancer Biology. PMID 34670140 DOI: 10.1016/j.semcancer.2021.10.005   
2021 Teng H, Yuan Y, Bar-Joseph Z. Clustering Spatial Transcriptomics Data. Bioinformatics (Oxford, England). PMID 34623423 DOI: 10.1093/bioinformatics/btab704   
2021 Brandi J, Lehmann C, Kaminski LC, Schulze Zur Wiesch J, Addo M, Ramharter M, Mackroth M, Jacobs T, Riehn M. T cells expressing multiple co-inhibitory molecules in acute malaria are not exhausted but exert a suppressive function in mice. European Journal of Immunology. PMID 34752634 DOI: 10.1002/eji.202149424   
2021 Lee G, Karunanithi S, Posner B, Niederstrasser H, Cheng H, Federov Y, Manjappa S, Musaitif K, Wang H, Jackson Z, Wald D. Chemical screening identifies novel small molecule activators of natural killer cell cytotoxicity against cancer cells. Cancer Immunology, Immunotherapy : Cii. PMID 34816323 DOI: 10.1007/s00262-021-03117-w   
2021 Pan D, Li H, Liu H, Sun X. [A review on integration methods for single-cell data]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi. 38: 1010-1017. PMID 34713670 DOI: 10.7507/1001-5515.202104073   
2021 Li N, Guo L, Guo H. Establishment, characterization, and transfection potential of a new continuous fish cell line (CAM) derived from the muscle tissue of grass goldfish (Carassius auratus). In Vitro Cellular & Developmental Biology. Animal. PMID 34725799 DOI: 10.1007/s11626-021-00622-1   
2021 Zhou WM, Yan YY, Guo QR, Ji H, Wang H, Xu TT, Makabel B, Pilarsky C, He G, Yu XY, Zhang JY. Microfluidics applications for high-throughput single cell sequencing. Journal of Nanobiotechnology. 19: 312. PMID 34635104 DOI: 10.1186/s12951-021-01045-6   
2021 Wu Z, Gao S, Watanabe N, Batchu S, Kajigaya S, Diamond C, Alemu L, Raffo DQ, Feng X, Hoffmann P, Stone D, Ombrello A, Young NS. Single-cell profiling of T lymphocytes in deficiency of adenosine deaminase 2. Journal of Leukocyte Biology. PMID 34730257 DOI: 10.1002/JLB.5A0621-314R