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Elissa J. Chesler - Publications

Affiliations: 
Oak Ridge National Laboratory, Oak Ridge, TN, United States 
Area:
neurogenetics, alcoholism, gene expression, statistical genetics, behavior genetics
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166 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Johnson EO, Fisher HS, Sullivan KA, Corradin O, Sanchez-Roige S, Gaddis NC, Sami YN, Townsend A, Teixeira Prates E, Pavicic M, Kruse P, Chesler EJ, Palmer AA, Troiani V, Bubier JA, et al. An emerging multi-omic understanding of the genetics of opioid addiction. The Journal of Clinical Investigation. 134. PMID 39403933 DOI: 10.1172/JCI172886  0.661
2024 Mitra A, Deats SP, Dickson PE, Zhu J, Gardin J, Nieman BJ, Henkelman RM, Tsai NP, Chesler EJ, Zhang ZW, Kumar V. is a regulator of cocaine responses through control of striatal and cortical excitability, and drug-induced plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 38508714 DOI: 10.1523/JNEUROSCI.1389-23.2024  0.725
2024 Ball RL, Bogue MA, Liang H, Srivastava A, Ashbrook DG, Lamoureux A, Gerring MW, Hatoum AS, Kim MJ, He H, Emerson J, Berger AK, Walton DO, Sheppard K, El Kassaby B, ... ... Chesler EJ, et al. GenomeMUSter mouse genetic variation service enables multitrait, multipopulation data integration and analysis. Genome Research. PMID 38290977 DOI: 10.1101/gr.278157.123  0.782
2024 Roy TA, Bubier JA, Dickson PE, Wilcox TD, Ndukum J, Clark JW, Sukoff Rizzo SJ, Crabbe JC, Denegre JM, Svenson KL, Braun RE, Kumar V, Murray SA, White JK, Philip VM, ... Chesler EJ, et al. Discovery and validation of genes driving drug-intake and related behavioral traits in mice. Genes, Brain, and Behavior. e12875. PMID 38164795 DOI: 10.1111/gbb.12875  0.818
2023 Ball RL, Bogue MA, Liang H, Srivastava A, Ashbrook DG, Lamoureux A, Gerring MW, Hatoum AS, Kim M, He H, Emerson J, Berger AK, Walton DO, Sheppard K, Kassaby BE, ... ... Chesler EJ, et al. GenomeMUSter mouse genetic variation service enables multi-trait, multi-population data integration and analyses. Biorxiv : the Preprint Server For Biology. PMID 37609331 DOI: 10.1101/2023.08.08.552506  0.785
2023 Philip VM, He H, Saul MC, Dickson PE, Bubier JA, Chesler EJ. Gene expression genetics of the striatum of Diversity Outbred mice. Scientific Data. 10: 522. PMID 37543624 DOI: 10.1038/s41597-023-02426-2  0.83
2023 Roy TA, Bubier JA, Dickson PE, Wilcox TD, Ndukum J, Clark JW, Sukoff Rizzo SJ, Crabbe JC, Denegre JM, Svenson KL, Braun RE, Kumar V, Murray SA, White JK, Philip VM, ... Chesler EJ, et al. DISCOVERY AND VALIDATION OF GENES DRIVING DRUG-INTAKE AND RELATED BEHAVIORAL TRAITS IN MICE. Biorxiv : the Preprint Server For Biology. PMID 37503148 DOI: 10.1101/2023.07.09.548280  0.812
2023 Philip VM, He H, Saul MC, Dickson PE, Bubier JA, Chesler EJ. Gene expression genetics of the striatum of Diversity Outbred mice. Biorxiv : the Preprint Server For Biology. PMID 37214980 DOI: 10.1101/2023.05.11.540390  0.83
2023 Tran TDB, Monroy Hernandez C, Nguyen H, Wright S, Tarantino LM, Chesler EJ, Weinstock GM, Zhou Y, Bubier JA. The microbial community dynamics of cocaine sensitization in two behaviorally divergent strains of collaborative cross mice. Genes, Brain, and Behavior. e12845. PMID 37114320 DOI: 10.1111/gbb.12845  0.775
2023 Raza A, Diehl SA, Krementsov DN, Case LK, Li D, Kost J, Ball RL, Chesler EJ, Philip VM, Huang R, Chen Y, Ma R, Tyler AL, Mahoney JM, Blankenhorn EP, et al. A genetic locus complements resistance to Bordetella pertussis-induced histamine sensitization. Communications Biology. 6: 244. PMID 36879097 DOI: 10.1038/s42003-023-04603-w  0.309
2022 Bagley JR, Bailey LS, Gagnon LH, He H, Philip VM, Reinholdt LG, Tarantino LM, Chesler EJ, Jentsch JD. Behavioral phenotypes revealed during reversal learning are linked with novel genetic loci in diversity outbred mice. Addiction Neuroscience. 4. PMID 36714272 DOI: 10.1016/j.addicn.2022.100045  0.412
2022 Binh Tran TD, Nguyen H, Sodergren E, Addiction CFSNO, Dickson PE, Wright SN, Philip VM, Weinstock GM, Chesler EJ, Zhou Y, Bubier JA. Microbial glutamate metabolism predicts intravenous cocaine self-administration in diversity outbred mice. Neuropharmacology. 109409. PMID 36592885 DOI: 10.1016/j.neuropharm.2022.109409  0.798
2022 Schoenrock SA, Gagnon L, Olson A, Leonardo M, Philip VM, He H, Reinholdt LG, Sukoff Rizzo SJ, Jentsch JD, Chesler EJ, Tarantino LM. The collaborative cross strains and their founders vary widely in cocaine-induced behavioral sensitization. Frontiers in Behavioral Neuroscience. 16: 886524. PMID 36275853 DOI: 10.3389/fnbeh.2022.886524  0.692
2022 Bailey LS, Bagley JR, Wherry JD, Chesler EJ, Karkhanis A, Jentsch JD, Tarantino LM. Repeated dosing with cocaine produces strain-dependent effects on responding for conditioned reinforcement in Collaborative Cross mice. Psychopharmacology. PMID 36239767 DOI: 10.1007/s00213-022-06256-9  0.307
2022 Parker CC, Philip VM, Gatti DM, Kasparek S, Kreuzman AM, Kuffler L, Mansky B, Masneuf S, Sharif K, Sluys E, Taterra D, Taylor WM, Thomas M, Polesskaya O, Palmer AA, ... ... Chesler EJ, et al. Genome-wide association mapping of ethanol sensitivity in the Diversity Outbred mouse population. Alcoholism, Clinical and Experimental Research. PMID 35383961 DOI: 10.1111/acer.14825  0.375
2021 Wotton JM, Peterson E, Flenniken AM, Bains RS, Veeraragavan S, Bower LR, Bubier JA, Parisien M, Bezginov A, Haselimashhadi H, Mason J, Moore MA, Stewart ME, Clary DA, Delbarre DJ, ... ... Chesler EJ, et al. Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen. Pain. 163: 1139-1157. PMID 35552317 DOI: 10.1097/j.pain.0000000000002481  0.695
2021 Huggett SB, Johnson EC, Hatoum AS, Lai D, Srijeyanthan J, Bubier JA, Chesler EJ, Agrawal A, Palmer AA, Edenberg HJ, Palmer RHC. Genes identified in rodent studies of alcohol intake are enriched for heritability of human substance use. Alcoholism, Clinical and Experimental Research. PMID 34751961 DOI: 10.1111/acer.14738  0.661
2021 Bailey LS, Bagley JR, Dodd R, Olson A, Bolduc M, Philip VM, Reinholdt LG, Sukoff Rizzo SJ, Tarantino L, Gagnon L, Chesler EJ, Jentsch JD. Heritable variation in locomotion, reward sensitivity and impulsive behaviors in a genetically diverse inbred mouse panel. Genes, Brain, and Behavior. PMID 34672075 DOI: 10.1111/gbb.12773  0.385
2021 Phillips TJ, Roy T, Aldrich SJ, Baba H, Erk J, Mootz JRK, Reed C, Chesler EJ. Confirmation of a Causal Allelic Variant in Addiction-Relevant Methamphetamine Behaviors. Frontiers in Psychiatry. 12: 725839. PMID 34512422 DOI: 10.3389/fpsyt.2021.725839  0.306
2021 Hitzemann R, Bergeson SE, Berman AE, Bubier JA, Chesler EJ, Finn DA, Hein M, Hoffman P, Holmes A, Kisby BR, Lockwood D, Lodowski KH, McManus M, Owen JA, Ozburn AR, et al. Sex Differences in the Brain Transcriptome Related to Alcohol Effects and Alcohol Use Disorder. Biological Psychiatry. PMID 34274109 DOI: 10.1016/j.biopsych.2021.04.016  0.664
2021 Bubier JA, Chesler EJ, Weinstock GM. Host genetic control of gut microbiome composition. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 34159422 DOI: 10.1007/s00335-021-09884-2  0.69
2021 Palmer RHC, Johnson EC, Won H, Polimanti R, Kapoor M, Chitre A, Bogue MA, Benca-Bachman CE, Parker CC, Ursu O, Verma A, Reynolds T, Ernst J, Bray M, Kwon SB, ... ... Chesler EJ, et al. Integration of Evidence across Human and Model Organism Studies: A Meeting Report. Genes, Brain, and Behavior. e12738. PMID 33893716 DOI: 10.1111/gbb.12738  0.466
2021 Bagley JR, Chesler EJ, Philip VM, Jentsch JD. Heritability of Ethanol Consumption and Pharmacokinetics in a Genetically Diverse Panel of Collaborative Cross Mouse Strains and Their Inbred Founders. Alcoholism, Clinical and Experimental Research. PMID 33619752 DOI: 10.1111/acer.14582  0.326
2021 Palmer RHC, Benca-Bachman CE, Huggett SB, Bubier JA, McGeary JE, Ramgiri N, Srijeyanthan J, Yang J, Visscher PM, Yang J, Knopik VS, Chesler EJ. Multi-omic and multi-species meta-analyses of nicotine consumption. Translational Psychiatry. 11: 98. PMID 33542196 DOI: 10.1038/s41398-021-01231-y  0.665
2021 Kim SM, Vadnie CA, Philip VM, Gagnon LH, Chowdari KV, Chesler EJ, McClung CA, Logan RW. High-throughput measurement of fibroblast rhythms reveals genetic heritability of circadian phenotypes in diversity outbred mice and their founder strains. Scientific Reports. 11: 2573. PMID 33510298 DOI: 10.1038/s41598-021-82069-8  0.342
2020 Wotton JM, Peterson E, Anderson L, Murray SA, Braun RE, Chesler EJ, White JK, Kumar V. Machine learning-based automated phenotyping of inflammatory nocifensive behavior in mice. Molecular Pain. 16: 1744806920958596. PMID 32955381 DOI: 10.1177/1744806920958596  0.35
2020 Thomas AL, Evans LM, Nelsen MD, Chesler EJ, Powers MS, Booher WC, Lowry CA, DeFries JC, Ehringer MA. Whole-Genome Sequencing of Inbred Mouse Strains Selected for High and Low Open-Field Activity. Behavior Genetics. PMID 32939625 DOI: 10.1007/S10519-020-10014-Y  0.385
2020 Bubier JA, He H, Philip VM, Roy T, Hernandez CM, Bernat R, Donohue KD, O'Hara BF, Chesler EJ. Genetic variation regulates opioid-induced respiratory depression in mice. Scientific Reports. 10: 14970. PMID 32917924 DOI: 10.1038/S41598-020-71804-2  0.697
2020 Ouellette AR, Neuner SM, Dumitrescu L, Anderson LC, Gatti DM, Mahoney ER, Bubier JA, Churchill G, Peters L, Huentelman MJ, Herskowitz JH, Yang HS, Smith AN, Reitz C, Kunkle BW, ... ... Chesler EJ, et al. Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia. Cell Reports. 32: 108091. PMID 32877673 DOI: 10.1016/J.Celrep.2020.108091  0.674
2020 Reynolds T, Johnson E, Huggett S, Bubier JA, Palmer RHC, Agrawal A, Baker EJ, Chesler EJ. Interpretation of psychiatric genome-wide association studies with multispecies heterogeneous functional genomic data integration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32791514 DOI: 10.1038/S41386-020-00795-5  0.735
2020 Bubier JA, Philip VM, Dickson PE, Mittleman G, Chesler EJ. Discovery of a Role for in Habituation and Cocaine Induced Locomotor Activation in Mice Using Heterogeneous Functional Genomic Analysis. Frontiers in Neuroscience. 14: 721. PMID 32742255 DOI: 10.3389/Fnins.2020.00721  0.809
2020 Tuttle AH, Philip VM, Chesler EJ, Mogil JS. Author Correction: Comparing phenotypic variation between inbred and outbred mice. Nature Methods. PMID 32728193 DOI: 10.1038/s41592-020-0932-7  0.546
2020 Huggett SB, Bubier JA, Chesler EJ, Palmer RHC. Do gene expression findings from mouse models of cocaine use recapitulate human cocaine use disorder in reward circuitry? Genes, Brain, and Behavior. e12689. PMID 32720468 DOI: 10.1111/Gbb.12689  0.695
2020 Yang JH, Presby RE, Cayer S, Rotolo RA, Perrino PA, Fitch RH, Correa M, Chesler EJ, Salamone JD. Effort-related decision making in humanized COMT mice: Effects of ValMet polymorphisms and possible implications for negative symptoms in humans. Pharmacology, Biochemistry, and Behavior. 196: 172975. PMID 32593787 DOI: 10.1016/J.Pbb.2020.172975  0.482
2020 Datta U, Schoenrock SE, Bubier JA, Bogue MA, Jentsch JD, Logan RW, Tarantino LM, Chesler EJ. Prospects for finding the mechanisms of sex differences in addiction with human and model organism genetic analysis. Genes, Brain, and Behavior. PMID 32012419 DOI: 10.1111/Gbb.12645  0.704
2020 Schoenrock SA, Kumar P, Gómez-A A, Dickson PE, Kim SM, Bailey L, Neira S, Riker KD, Farrington J, Gaines CH, Khan S, Wilcox TD, Roy TA, Leonardo MR, Olson AA, ... ... Chesler EJ, et al. Characterization of genetically complex Collaborative Cross mouse strains that model divergent locomotor activating and reinforcing properties of cocaine. Psychopharmacology. PMID 31897574 DOI: 10.1007/S00213-019-05429-3  0.82
2020 Bubier JA, Philip VM, Quince C, Campbell J, Zhou Y, Vishnivetskaya T, Duvvuru S, Hageman Blair R, Ndukum J, Donohue KD, Foster CM, Mellert DJ, Weinstock G, Culiat CT, O'Hara B, ... ... Chesler EJ, et al. A Microbe Associated with Sleep Revealed by a Novel Systems-Genetic Analysis of the Microbiome in Collaborative Cross Mice. Genetics. PMID 31896565 DOI: 10.1534/Genetics.119.303013  0.7
2019 Boehm FJ, Chesler EJ, Yandell BS, Broman KW. Testing Pleiotropy vs. Separate QTL in Multiparental Populations. G3 (Bethesda, Md.). 9: 2317-2324. PMID 33877348 DOI: 10.1534/g3.119.400098  0.329
2019 Bogue MA, Philip VM, Walton DO, Grubb SC, Dunn MH, Kolishovski G, Emerson J, Mukherjee G, Stearns T, He H, Sinha V, Kadakkuzha B, Kunde-Ramamoorthy G, Chesler EJ. Mouse Phenome Database: a data repository and analysis suite for curated primary mouse phenotype data. Nucleic Acids Research. PMID 31696236 DOI: 10.1093/Nar/Gkz1032  0.436
2019 Phillips CA, Wang K, Baker EJ, Bubier JA, Chesler EJ, Langston MA. On Finding and Enumerating Maximal and Maximum -Partite Cliques in -Partite Graphs. Algorithms. 12. PMID 31448059 DOI: 10.3390/A12010023  0.617
2019 Recla JM, Bubier JA, Gatti DM, Ryan JL, Long KH, Robledo RF, Glidden NC, Hou G, Churchill GA, Maser RS, Zhang ZW, Young EE, Chesler EJ, Bult CJ. Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response. Pain. 160: 1740-1753. PMID 31335644 DOI: 10.1097/J.Pain.0000000000001571  0.706
2019 Saul MC, Philip VM, Reinholdt LG, Chesler EJ. High-Diversity Mouse Populations for Complex Traits. Trends in Genetics : Tig. PMID 31133439 DOI: 10.1016/J.Tig.2019.04.003  0.453
2019 Skelly DA, Raghupathy N, Robledo RF, Graber JH, Chesler EJ. Reference Trait Analysis Reveals Correlations Between Gene Expression and Quantitative Traits in Disjoint Samples. Genetics. PMID 31113812 DOI: 10.1534/Genetics.118.301865  0.351
2019 Boehm FJ, Chesler EJ, Yandell BS, Broman KW. Testing Pleiotropy Separate QTL in Multiparental Populations. G3 (Bethesda, Md.). PMID 31092608 DOI: 10.1534/G3.119.400098  0.323
2019 Bubier JA, Sutphin GL, Reynolds TJ, Korstanje R, Fuksman-Kumpa A, Baker EJ, Langston MA, Chesler EJ. Integration of heterogeneous functional genomics data in gerontology research to find genes and pathway underlying aging across species. Plos One. 14: e0214523. PMID 30978202 DOI: 10.1371/Journal.Pone.0214523  0.672
2019 Recla JM, Bubier JA, Gatti DM, Ryan JL, Long KH, Robledo RF, Glidden NC, Hou G, Churchill GA, Maser RS, Zhang ZW, Young EE, Chesler EJ, Bult CJ. Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response. Pain. PMID 30925521 DOI: 10.1097/j.pain.0000000000001571  0.705
2019 Bubier J, Hill D, Mukherjee G, Reynolds T, Baker EJ, Berger A, Emerson J, Blake JA, Chesler EJ. Curating gene sets: challenges and opportunities for integrative analysis. Database : the Journal of Biological Databases and Curation. 2019. PMID 30888410 DOI: 10.1093/Database/Baz036  0.681
2019 Palmer R, Benca-Bachman C, Bubier J, Ramgiri N, Srijeyanthan J, Chesler E. Cross-Species Prioritization Of Genomic Loci For Nicotine & Alcohol Use Disorders European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.07.025  0.651
2018 Tuttle AH, Philip VM, Chesler EJ, Mogil JS. Author Correction: Comparing phenotypic variation between inbred and outbred mice. Nature Methods. PMID 30584248 DOI: 10.1038/s41592-018-0298-2  0.467
2018 Tuttle AH, Philip VM, Chesler EJ, Mogil JS. Comparing phenotypic variation between inbred and outbred mice. Nature Methods. 15: 994-996. PMID 30504873 DOI: 10.1038/s41592-018-0224-7  0.564
2018 Dickson PE, Roy TA, McNaughton KA, Wilcox TD, Kumar P, Chesler EJ. Systems genetics of sensation seeking. Genes, Brain, and Behavior. e12519. PMID 30221471 DOI: 10.1111/Gbb.12519  0.79
2018 Yuan JT, Gatti DM, Philip VM, Kasparek S, Kreuzman AM, Mansky B, Sharif K, Taterra D, Taylor WM, Thomas M, Ward JO, Holmes A, Chesler EJ, Parker CC. Genome-wide association for testis weight in the diversity outbred mouse population. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 29691636 DOI: 10.1007/S00335-018-9745-8  0.481
2018 Kafkafi N, Agassi J, Chesler EJ, Crabbe JC, Crusio WE, Eilam D, Gerlai R, Golani I, Gomez-Marin A, Heller R, Iraqi F, Jaljuli I, Karp NA, Morgan H, Nicholson G, et al. Reproducibility and replicability of rodent phenotyping in preclinical studies. Neuroscience and Biobehavioral Reviews. PMID 29357292 DOI: 10.1016/J.Neubiorev.2018.01.003  0.431
2018 Gunduz-Cinar O, Brockway E, Lederle L, Wilcox T, Halladay LR, Ding Y, Oh H, Busch EF, Kaugars K, Flynn S, Limoges A, Bukalo O, MacPherson KP, Masneuf S, Pinard C, ... ... Chesler EJ, et al. Identification of a novel gene regulating amygdala-mediated fear extinction. Molecular Psychiatry. PMID 29311651 DOI: 10.1038/S41380-017-0003-3  0.433
2017 Bogue MA, Grubb SC, Walton DO, Philip VM, Kolishovski G, Stearns T, Dunn MH, Skelly DA, Kadakkuzha B, TeHennepe G, Kunde-Ramamoorthy G, Chesler EJ. Mouse Phenome Database: an integrative database and analysis suite for curated empirical phenotype data from laboratory mice. Nucleic Acids Research. PMID 29136208 DOI: 10.1093/Nar/Gkx1082  0.471
2017 Shorter JR, Odet F, Aylor DL, Pan W, Kao CY, Fu CP, Morgan AP, Greenstein S, Bell TA, Stevans AM, Feathers RW, Patel S, Cates SE, Shaw GD, Miller DR, ... Chesler EJ, et al. Male Infertility Is Responsible for Nearly Half of the Extinction Observed in the Mouse Collaborative Cross. Genetics. 206: 557-572. PMID 28592496 DOI: 10.1534/Genetics.116.199596  0.414
2017 Delprato A, Algéo MP, Bonheur B, Bubier JA, Lu L, Williams RW, Chesler EJ, Crusio WE. QTL and Systems Genetics Analysis of Mouse Grooming and Behavioral Responses to Novelty in an Open Field. Genes, Brain, and Behavior. PMID 28544613 DOI: 10.1111/Gbb.12392  0.769
2017 Parker CC, Dickson PE, Philip VM, Thomas M, Chesler EJ. Systems Genetic Analysis in GeneNetwork.org. Current Protocols in Neuroscience. 79: 8.39.1-8.39.20. PMID 28398643 DOI: 10.1002/Cpns.23  0.774
2017 Bubier JA, Langston MA, Baker EJ, Chesler EJ. Integrative Functional Genomics for Systems Genetics in GeneWeaver.org. Methods in Molecular Biology (Clifton, N.J.). 1488: 131-152. PMID 27933523 DOI: 10.1007/978-1-4939-6427-7_6  0.721
2016 Crusio WE, Dhawan E, Chesler EJ, Delprato A. Analysis of morphine responses in mice reveals a QTL on Chromosome 7. F1000research. 5: 2156. PMID 27746909 DOI: 10.12688/F1000Research.9484.2  0.38
2016 Chesler EJ, Gatti DM, Morgan AP, Strobel M, Trepanier L, Oberbeck D, McWeeney S, Hitzemann R, Ferris M, McMullan R, Clayshultle A, Bell TA, Pardo-Manuel de Villena F, Churchill GA. Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection. G3 (Bethesda, Md.). PMID 27694113 DOI: 10.1534/G3.116.035527  0.305
2016 Young EE, Bryant CD, Lee SE, Peng X, Cook B, Nair HK, Dreher KJ, Zhang X, Palmer AA, Chung JM, Mogil JS, Chesler EJ, Lariviere WR. Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test. Genes, Brain, and Behavior. PMID 27231153 DOI: 10.1111/Gbb.12302  0.642
2016 Putman AH, Wolen AR, Harenza J, Yordanova RK, Webb BT, Chesler EJ, Miles MF. Identification of Quantitative Trait Loci and Candidate Genes for an Anxiolytic-like Response to Ethanol in BXD Recombinant Inbred Strains. Genes, Brain, and Behavior. PMID 26948279 DOI: 10.1111/Gbb.12289  0.437
2016 Didion JP, Morgan AP, Yadgary L, Bell TA, McMullan RC, Ortiz de Solorzano L, Britton-Davidian J, Bult CJ, Campbell KJ, Castiglia R, Ching YH, Chunco AJ, Crowley JJ, Chesler EJ, Förster DW, et al. R2d2 drives selfish sweeps in the house mouse. Molecular Biology and Evolution. PMID 26882987 DOI: 10.1093/Molbev/Msw036  0.419
2016 Bubier JA, Wilcox TD, Jay JJ, Langston MA, Baker EJ, Chesler EJ. Cross-Species Integrative Functional Genomics in GeneWeaver Reveals a Role for Pafah1b1 in Altered Response to Alcohol. Frontiers in Behavioral Neuroscience. 10: 1. PMID 26834590 DOI: 10.3389/Fnbeh.2016.00001  0.682
2015 Baker E, Bubier JA, Reynolds T, Langston MA, Chesler EJ. GeneWeaver: data driven alignment of cross-species genomics in biology and disease. Nucleic Acids Research. PMID 26656951 DOI: 10.1093/Nar/Gkv1329  0.665
2015 Dickson PE, Miller MM, Calton MA, Bubier JA, Cook MN, Goldowitz D, Chesler EJ, Mittleman G. Systems genetics of intravenous cocaine self-administration in the BXD recombinant inbred mouse panel. Psychopharmacology. PMID 26581503 DOI: 10.1007/S00213-015-4147-Z  0.808
2015 Bogue MA, Churchill GA, Chesler EJ. Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 26286858 DOI: 10.1007/S00335-015-9595-6  0.414
2015 Dickson PE, McNaughton KA, Hou L, Anderson LC, Long KH, Chesler EJ. Sex and strain influence attribution of incentive salience to reward cues in mice. Behavioural Brain Research. PMID 26102561 DOI: 10.1016/J.Bbr.2015.05.039  0.772
2015 Bubier JA, Phillips CA, Langston MA, Baker EJ, Chesler EJ. GeneWeaver: finding consilience in heterogeneous cross-species functional genomics data. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 26092690 DOI: 10.1007/S00335-015-9575-X  0.707
2015 Ackert-Bicknell CL, Anderson LC, Sheehan S, Hill WG, Chang B, Churchill GA, Chesler EJ, Korstanje R, Peters LL. Aging Research Using Mouse Models. Current Protocols in Mouse Biology. 5: 95-133. PMID 26069080 DOI: 10.1002/9780470942390.Mo140195  0.331
2015 Karp NA, Meehan TF, Morgan H, Mason JC, Blake A, Kurbatova N, Smedley D, Jacobsen J, Mott RF, Iyer V, Matthews P, Melvin DG, Wells S, Flenniken AM, Masuya H, ... ... Chesler EJ, et al. Applying the ARRIVE Guidelines to an In Vivo Database. Plos Biology. 13: e1002151. PMID 25992600 DOI: 10.1371/Journal.Pbio.1002151  0.302
2015 Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, et al. A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2. Plos Genetics. 11: e1004850. PMID 25679959 DOI: 10.1371/Journal.Pgen.1004850  0.425
2015 Padula AE, Griffin WC, Lopez MF, Nimitvilai S, Cannady R, McGuier NS, Chesler EJ, Miles MF, Williams RW, Randall PK, Woodward JJ, Becker HC, Mulholland PJ. KCNN Genes that Encode Small-Conductance Ca(2+)-Activated K(+) Channels Influence Alcohol and Drug Addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1928-39. PMID 25662840 DOI: 10.1038/Npp.2015.42  0.48
2015 Ha T, Swanson D, Larouche M, Glenn R, Weeden D, Zhang P, Hamre K, Langston M, Phillips C, Song M, Ouyang Z, Chesler E, Duvvurru S, Yordanova R, Cui Y, et al. CbGRiTS: cerebellar gene regulation in time and space. Developmental Biology. 397: 18-30. PMID 25446528 DOI: 10.1016/J.Ydbio.2014.09.032  0.39
2015 Dickson PE, Ndukum J, Wilcox T, Clark J, Roy B, Zhang L, Li Y, Lin DT, Chesler EJ. Association of novelty-related behaviors and intravenous cocaine self-administration in Diversity Outbred mice. Psychopharmacology. 232: 1011-24. PMID 25238945 DOI: 10.1007/S00213-014-3737-5  0.772
2015 Sethi M, Joshi SS, Striz M, Cole N, Ryan J, Lhamon ME, Agarwal A, Sukoff Rizzo SJ, Denegre JM, Braun RE, Fardo DW, Donohue KD, Chesler EJ, Svenson KL, O'Hara BF. Analysis of sleep traits in knockout mice from the large-scale KOMP2 population using a non-invasive, high-throughput piezoelectric system Bmc Bioinformatics. 16. DOI: 10.1186/1471-2105-16-S15-P15  0.332
2014 Baker E, Culpepper C, Philips C, Bubier J, Langston M, Chesler E. Identifying common components across biological network graphs using a bipartite data model. Bmc Proceedings. 8: S4. PMID 25374613 DOI: 10.1186/1753-6561-8-S6-S4  0.665
2014 Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA. Quantitative trait locus mapping methods for diversity outbred mice. G3 (Bethesda, Md.). 4: 1623-33. PMID 25237114 DOI: 10.1534/G3.114.013748  0.465
2014 Munger SC, Raghupathy N, Choi K, Simons AK, Gatti DM, Hinerfeld DA, Svenson KL, Keller MP, Attie AD, Hibbs MA, Graber JH, Chesler EJ, Churchill GA. RNA-Seq alignment to individualized genomes improves transcript abundance estimates in multiparent populations. Genetics. 198: 59-73. PMID 25236449 DOI: 10.1534/Genetics.114.165886  0.342
2014 Rutledge H, Aylor DL, Carpenter DE, Peck BC, Chines P, Ostrowski LE, Chesler EJ, Churchill GA, de Villena FP, Kelada SN. Genetic regulation of Zfp30, CXCL1, and neutrophilic inflammation in murine lung. Genetics. 198: 735-45. PMID 25114278 DOI: 10.1534/Genetics.114.168138  0.346
2014 Bubier JA, Jay JJ, Baker CL, Bergeson SE, Ohno H, Metten P, Crabbe JC, Chesler EJ. Identification of a QTL in Mus musculus for alcohol preference, withdrawal, and Ap3m2 expression using integrative functional genomics and precision genetics. Genetics. 197: 1377-93. PMID 24923803 DOI: 10.1534/Genetics.114.166165  0.73
2014 Recla JM, Robledo RF, Gatti DM, Bult CJ, Churchill GA, Chesler EJ. Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 25: 211-22. PMID 24700285 DOI: 10.1007/S00335-014-9508-0  0.466
2014 Kelada SN, Carpenter DE, Aylor DL, Chines P, Rutledge H, Chesler EJ, Churchill GA, Pardo-Manuel de Villena F, Schwartz DA, Collins FS. Integrative genetic analysis of allergic inflammation in the murine lung. American Journal of Respiratory Cell and Molecular Biology. 51: 436-45. PMID 24693920 DOI: 10.1165/Rcmb.2013-0501Oc  0.412
2014 Liu EY, Morgan AP, Chesler EJ, Wang W, Churchill GA, Pardo-Manuel de Villena F. High-resolution sex-specific linkage maps of the mouse reveal polarized distribution of crossovers in male germline. Genetics. 197: 91-106. PMID 24578350 DOI: 10.1534/Genetics.114.161653  0.343
2014 Chesler EJ. Out of the bottleneck: the Diversity Outcross and Collaborative Cross mouse populations in behavioral genetics research. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 25: 3-11. PMID 24272351 DOI: 10.1007/s00335-013-9492-9  0.445
2014 Jay JJ, Chesler EJ. Performing integrative functional genomics analysis in GeneWeaver.org. Methods in Molecular Biology (Clifton, N.J.). 1101: 13-29. PMID 24233775 DOI: 10.1007/978-1-62703-721-1_2  0.387
2014 Bubier J, Langston M, Baker E, Chesler E. Integrative functional genomic analysis using GeneWeaver F1000research. 5. DOI: 10.7490/F1000Research.1097189.1  0.651
2013 Logan RW, Robledo RF, Recla JM, Philip VM, Bubier JA, Jay JJ, Harwood C, Wilcox T, Gatti DM, Bult CJ, Churchill GA, Chesler EJ. High-precision genetic mapping of behavioral traits in the diversity outbred mouse population. Genes, Brain, and Behavior. 12: 424-37. PMID 23433259 DOI: 10.1111/Gbb.12029  0.747
2013 DuBose CS, Chesler EJ, Goldowitz D, Hamre KM. Use of the expanded panel of BXD mice narrow QTL regions in ethanol-induced locomotor activation and motor incoordination. Alcoholism, Clinical and Experimental Research. 37: 170-83. PMID 23289978 DOI: 10.1111/J.1530-0277.2012.01865.X  0.442
2012 Chesler EJ, Logan RW. Opportunities for bioinformatics in the classification of behavior and psychiatric disorders. International Review of Neurobiology. 104: 183-211. PMID 23195316 DOI: 10.1016/B978-0-12-398323-7.00008-2  0.322
2012 Haendel MA, Chesler EJ. Lost and found in behavioral informatics. International Review of Neurobiology. 103: 1-18. PMID 23195118 DOI: 10.1016/B978-0-12-388408-4.00001-0  0.35
2012 Parsons MJ, Grimm C, Paya-Cano JL, Fernandes C, Liu L, Philip VM, Chesler EJ, Nietfeld W, Lehrach H, Schalkwyk LC. Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains. Bmc Genomics. 13: 476. PMID 22974136 DOI: 10.1186/1471-2164-13-476  0.324
2012 Thaisz J, Tsaih SW, Feng M, Philip VM, Zhang Y, Yanas L, Sheehan S, Xu L, Miller DR, Paigen B, Chesler EJ, Churchill GA, Dipetrillo K. Genetic analysis of albuminuria in collaborative cross and multiple mouse intercross populations. American Journal of Physiology. Renal Physiology. 303: F972-81. PMID 22859403 DOI: 10.1152/Ajprenal.00690.2011  0.492
2012 Ha TJ, Swanson DJ, Kirova R, Yeung J, Choi K, Tong Y, Chesler EJ, Goldowitz D. Genome-wide microarray comparison reveals downstream genes of Pax6 in the developing mouse cerebellum. The European Journal of Neuroscience. 36: 2888-98. PMID 22817342 DOI: 10.1111/J.1460-9568.2012.08221.X  0.337
2012 Campbell JH, Foster CM, Vishnivetskaya T, Campbell AG, Yang ZK, Wymore A, Palumbo AV, Chesler EJ, Podar M. Host genetic and environmental effects on mouse intestinal microbiota. The Isme Journal. 6: 2033-44. PMID 22695862 DOI: 10.1038/Ismej.2012.54  0.399
2012 Bubier JA, Chesler EJ. Accelerating discovery for complex neurological and behavioral disorders through systems genetics and integrative genomics in the laboratory mouse. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 9: 338-48. PMID 22422471 DOI: 10.1007/S13311-012-0111-3  0.722
2012 Kelada SN, Aylor DL, Peck BC, Ryan JF, Tavarez U, Buus RJ, Miller DR, Chesler EJ, Threadgill DW, Churchill GA, Pardo-Manuel de Villena F, Collins FS. Genetic analysis of hematological parameters in incipient lines of the collaborative cross. G3 (Bethesda, Md.). 2: 157-65. PMID 22384394 DOI: 10.1534/G3.111.001776  0.454
2012 Chesler EJ, Plitt A, Fisher D, Hurd B, Lederle L, Bubier JA, Kiselycznyk C, Holmes A. Quantitative trait loci for sensitivity to ethanol intoxication in a C57BL/6J×129S1/SvImJ inbred mouse cross. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 305-21. PMID 22371272 DOI: 10.1007/S00335-012-9394-2  0.731
2012 Svenson KL, Gatti DM, Valdar W, Welsh CE, Cheng R, Chesler EJ, Palmer AA, McMillan L, Churchill GA. High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics. 190: 437-47. PMID 22345611 DOI: 10.1534/Genetics.111.132597  0.448
2012 Iraqi FA, Mahajne M, Salaymah Y, Sandovski H, Tayem H, Vered K, Balmer L, Hall M, Manship G, Morahan G, Pettit K, Scholten J, Tweedie K, Wallace A, Weerasekera L, ... ... Chesler EJ, et al. The genome architecture of the collaborative cross mouse genetic reference population Genetics. 190: 389-401. PMID 22345608 DOI: 10.1534/Genetics.111.132639  0.413
2012 Baker EJ, Jay JJ, Bubier JA, Langston MA, Chesler EJ. GeneWeaver: a web-based system for integrative functional genomics. Nucleic Acids Research. 40: D1067-76. PMID 22080549 DOI: 10.1093/Nar/Gkr968  0.702
2011 Gelinas R, Chesler EJ, Vasconcelos D, Miller DR, Yuan Y, Wang K, Galas D. A genetic approach to the prediction of drug side effects: bleomycin induces concordant phenotypes in mice of the collaborative cross. Pharmacogenomics and Personalized Medicine. 4: 35-45. PMID 23226052 DOI: 10.2147/PGPM.S22475  0.409
2011 Philip VM, Sokoloff G, Ackert-Bicknell CL, Striz M, Branstetter L, Beckmann MA, Spence JS, Jackson BL, Galloway LD, Barker P, Wymore AM, Hunsicker PR, Durtschi DC, Shaw GS, Shinpock S, ... ... Chesler EJ, et al. Genetic analysis in the Collaborative Cross breeding population. Genome Research. 21: 1223-38. PMID 21734011 DOI: 10.1101/Gr.113886.110  0.431
2011 Mathes WF, Aylor DL, Miller DR, Churchill GA, Chesler EJ, de Villena FP, Threadgill DW, Pomp D. Architecture of energy balance traits in emerging lines of the Collaborative Cross. American Journal of Physiology. Endocrinology and Metabolism. 300: E1124-34. PMID 21427413 DOI: 10.1152/Ajpendo.00707.2010  0.404
2011 Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, ... ... Chesler EJ, et al. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Research. 21: 1213-22. PMID 21406540 DOI: 10.1101/Gr.111310.110  0.48
2011 Meehan TF, Carr CJ, Jay JJ, Bult CJ, Chesler EJ, Blake JA. Autism candidate genes via mouse phenomics. Journal of Biomedical Informatics. 44: S5-11. PMID 21397722 DOI: 10.1016/J.Jbi.2011.03.003  0.437
2011 Dickson PE, Rogers TD, Lester DB, Miller MM, Matta SG, Chesler EJ, Goldowitz D, Blaha CD, Mittleman G. Genotype-dependent effects of adolescent nicotine exposure on dopamine functional dynamics in the nucleus accumbens shell in male and female mice: a potential mechanism underlying the gateway effect of nicotine. Psychopharmacology. 215: 631-42. PMID 21212937 DOI: 10.1007/S00213-010-2159-2  0.785
2011 Nair HK, Hain H, Quock RM, Philip VM, Chesler EJ, Belknap JK, Lariviere WR. Genomic loci and candidate genes underlying inflammatory nociception. Pain. 152: 599-606. PMID 21195549 DOI: 10.1016/J.Pain.2010.11.029  0.454
2011 Schile A, Svenson KL, Fancher KS, Valdar W, Chesler EJ, Churchill GA. Abstract B10: Diversity Outbred: A new, highly diverse mouse stock for toxicology and cancer. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-B10  0.441
2010 Gatti DM, Zhao N, Chesler EJ, Bradford BU, Shabalin AA, Yordanova R, Lu L, Rusyn I. Sex-specific gene expression in the BXD mouse liver. Physiological Genomics. 42: 456-68. PMID 20551147 DOI: 10.1152/Physiolgenomics.00110.2009  0.527
2010 Lynch RM, Naswa S, Rogers GL, Kania SA, Das S, Chesler EJ, Saxton AM, Langston MA, Voy BH. Identifying genetic loci and spleen gene coexpression networks underlying immunophenotypes in BXD recombinant inbred mice. Physiological Genomics. 41: 244-53. PMID 20179155 DOI: 10.1152/Physiolgenomics.00020.2010  0.442
2010 Spindler KR, Welton AR, Lim ES, Duvvuru S, Althaus IW, Imperiale JE, Daoud AI, Chesler EJ. The major locus for mouse adenovirus susceptibility maps to genes of the hematopoietic cell surface-expressed LY6 family. Journal of Immunology (Baltimore, Md. : 1950). 184: 3055-62. PMID 20164425 DOI: 10.4049/Jimmunol.0903363  0.434
2010 Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ. High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains. Genes, Brain, and Behavior. 9: 129-59. PMID 19958391 DOI: 10.1111/J.1601-183X.2009.00540.X  0.736
2010 Naswa S, Rogers GL, Lynch RM, Kania SA, Das S, Chesler EJ, Saxton AM, Voy BH, Langston MA. Inferring gene coexpression networks for low dose ionizing radiation using graph theoretical algorithms and systems genetics Bmc Bioinformatics. 11: 1-1. DOI: 10.1186/1471-2105-11-S4-O5  0.383
2009 Baker EJ, Jay JJ, Philip VM, Zhang Y, Li Z, Kirova R, Langston MA, Chesler EJ. Ontological Discovery Environment: a system for integrating gene-phenotype associations. Genomics. 94: 377-87. PMID 19733230 DOI: 10.1016/J.Ygeno.2009.08.016  0.414
2009 Saccone SF, Bierut LJ, Chesler EJ, Kalivas PW, Lerman C, Saccone NL, Uhl GR, Li CY, Philip VM, Edenberg HJ, Sherry ST, Feolo M, Moyzis RK, Rutter JL. Supplementing high-density SNP microarrays for additional coverage of disease-related genes: addiction as a paradigm. Plos One. 4: e5225. PMID 19381300 DOI: 10.1371/Journal.Pone.0005225  0.423
2009 Song MJ, Lewis CK, Lance ER, Chesler EJ, Yordanova RK, Langston MA, Lodowski KH, Bergeson SE. Reconstructing generalized logical networks of transcriptional regulation in mouse brain from temporal gene expression data. Eurasip Journal On Bioinformatics & Systems Biology. 545176. PMID 19300527 DOI: 10.1155/2009/545176  0.353
2009 Carneiro AM, Airey DC, Thompson B, Zhu CB, Lu L, Chesler EJ, Erikson KM, Blakely RD. Functional coding variation in recombinant inbred mouse lines reveals multiple serotonin transporter-associated phenotypes. Proceedings of the National Academy of Sciences of the United States of America. 106: 2047-52. PMID 19179283 DOI: 10.1073/Pnas.0809449106  0.719
2008 Chesler EJ, Miller DR, Branstetter LR, Galloway LD, Jackson BL, Philip VM, Voy BH, Culiat CT, Threadgill DW, Williams RW, Churchill GA, Johnson DK, Manly KF. The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 19: 382-9. PMID 18716833 DOI: 10.1007/S00335-008-9135-8  0.546
2008 Matthews DB, Chesler EJ, Cook MN, Cockroft J, Philip VM, Goldowitz D. Genetic mapping of vocalization to a series of increasing acute footshocks using B6.A consomic and B6.D2 congenic mouse strains. Behavior Genetics. 38: 417-23. PMID 18535899 DOI: 10.1007/S10519-008-9210-7  0.38
2008 Peirce JL, Broman KW, Lu L, Chesler EJ, Zhou G, Airey DC, Birmingham AE, Williams RW. Genome Reshuffling for Advanced Intercross Permutation (GRAIP): simulation and permutation for advanced intercross population analysis. Plos One. 3: e1977. PMID 18431467 DOI: 10.1371/Journal.Pone.0001977  0.785
2008 Hancock JM, Adams NC, Aidinis V, Blake A, Blake JA, Bogue M, Brown SDM, Chesler EJ, Davidson D, Duran C, Eppig JT, Gailus-Durner V, Gates H, Gkoutos GV, Greenaway S, et al. Integration of mouse phenome data resources (Mammalian Genome (2007) 18, 3, (157-163) DOI: 10.1007/s00335-007-9004-x) Mammalian Genome. 1-2. DOI: 10.1007/S00335-008-9099-8  0.419
2007 Rosen GD, Chesler EJ, Manly KF, Williams RW. An informatics approach to systems neurogenetics. Methods in Molecular Biology (Clifton, N.J.). 401: 287-303. PMID 18368372 DOI: 10.1007/978-1-59745-520-6_16  0.57
2007 Cook MN, Dunning JP, Wiley RG, Chesler EJ, Johnson DK, Miller DR, Goldowitz D. Neurobehavioral mutants identified in an ENU-mutagenesis project. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 559-72. PMID 17629744 DOI: 10.1007/S00335-007-9035-3  0.34
2007 Gatti D, Maki A, Chesler EJ, Kirova R, Kosyk O, Lu L, Manly KF, Williams RW, Perkins A, Langston MA, Threadgill DW, Rusyn I. Genome-level analysis of genetic regulation of liver gene expression networks. Hepatology (Baltimore, Md.). 46: 548-57. PMID 17542012 DOI: 10.1002/Hep.21682  0.63
2007 Hancock JM, Adams NC, Aidinis V, Blake A, Bogue M, Brown SD, Chesler EJ, Davidson D, Duran C, Eppig JT, Gailus-Durner V, Gates H, Gkoutos GV, Greenaway S, et al. Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 157-63. PMID 17436037 DOI: 10.1007/S00335-007-9004-X  0.419
2006 Voy BH, Scharff JA, Perkins AD, Saxton AM, Borate B, Chesler EJ, Branstetter LK, Langston MA. Extracting gene networks for low-dose radiation using graph theoretical algorithms. Plos Computational Biology. 2: e89. PMID 16854212 DOI: 10.1371/Journal.Pcbi.0020089  0.337
2006 Goldowitz D, Matthews DB, Hamre KM, Mittleman G, Chesler EJ, Becker HC, Lopez MF, Jones SR, Mathews TA, Miles MF, Kerns R, Grant KA. Progress in using mouse inbred strains, consomics, and mutants to identify genes related to stress, anxiety, and alcohol phenotypes. Alcoholism, Clinical and Experimental Research. 30: 1066-78. PMID 16737467 DOI: 10.1111/J.1530-0277.2006.00125.X  0.647
2006 Kempermann G, Chesler EJ, Lu L, Williams RW, Gage FH. Natural variation and genetic covariance in adult hippocampal neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 780-5. PMID 16407118 DOI: 10.1073/Pnas.0510291103  0.582
2006 Li H, Chen H, Bao L, Manly KF, Chesler EJ, Lu L, Wang J, Zhou M, Williams RW, Cui Y. Integrative genetic analysis of transcription modules: towards filling the gap between genetic loci and inherited traits. Human Molecular Genetics. 15: 481-92. PMID 16371421 DOI: 10.1093/hmg/ddi462  0.632
2006 Chesler EJ, Bystrykh L, De Haan G, Cooke MP, Su A, Manly KF, Williams RW. Reply: Normalization procedures and detection of linkage signal in genetical-genomics experiments [5] Nature Genetics. 38: 856-858. DOI: 10.1038/ng0806-856  0.418
2005 Johnson DK, Rinchik EM, Moustaid-Moussa N, Miller DR, Williams RW, Michaud EJ, Jablonski MM, Elberger A, Hamre K, Smeyne R, Chesler E, Goldowitz D. Phenotype screening for genetically determined age-onset disorders and increased longevity in ENU-mutagenized mice. Age (Dordrecht, Netherlands). 27: 75-90. PMID 23598606 DOI: 10.1007/S11357-005-4131-3  0.516
2005 Vazquez-Chona FR, Khan AN, Chan CK, Moore AN, Dash PK, Hernandez MR, Lu L, Chesler EJ, Manly KF, Williams RW, Geisert EE. Genetic networks controlling retinal injury. Molecular Vision. 11: 958-70. PMID 16288200  0.507
2005 Bennett B, Carosone-Link PJ, Lu L, Chesler EJ, Johnson TE. Genetics of body weight in the LXS recombinant inbred mouse strains. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 16: 764-74. PMID 16261418 DOI: 10.1007/S00335-005-0002-6  0.482
2005 Matthews DB, Bhave SV, Belknap JK, Brittingham C, Chesler EJ, Hitzemann RJ, Hoffmann PL, Lu L, McWeeney S, Miles MF, Tabakoff B, Williams RW. Complex genetics of interactions of alcohol and CNS function and behavior. Alcoholism, Clinical and Experimental Research. 29: 1706-19. PMID 16205371 DOI: 10.1097/01.Alc.0000179209.44407.Df  0.592
2005 Mogil JS, Miermeister F, Seifert F, Strasburg K, Zimmermann K, Reinold H, Austin JS, Bernardini N, Chesler EJ, Hofmann HA, Hordo C, Messlinger K, Nemmani KV, Rankin AL, Ritchie J, et al. Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene. Proceedings of the National Academy of Sciences of the United States of America. 102: 12938-43. PMID 16118273 DOI: 10.1073/Pnas.0503264102  0.652
2005 Welton AR, Chesler EJ, Sturkie C, Jackson AU, Hirsch GN, Spindler KR. Identification of quantitative trait loci for susceptibility to mouse adenovirus type 1. Journal of Virology. 79: 11517-22. PMID 16103204 DOI: 10.1128/JVI.79.17.11517-11522.2005  0.438
2005 Baldwin NE, Chesler EJ, Kirov S, Langston MA, Snoddy JR, Williams RW, Zhang B. Computational, integrative, and comparative methods for the elucidation of genetic coexpression networks. Journal of Biomedicine & Biotechnology. 2005: 172-80. PMID 16046823 DOI: 10.1155/Jbb.2005.172  0.573
2005 Mhyre TR, Chesler EJ, Thiruchelvam M, Lungu C, Cory-Slechta DA, Fry JD, Richfield EK. Heritability, correlations and in silico mapping of locomotor behavior and neurochemistry in inbred strains of mice. Genes, Brain, and Behavior. 4: 209-28. PMID 15924554 DOI: 10.1111/J.1601-183X.2004.00102.X  0.475
2005 Li H, Lu L, Manly KF, Chesler EJ, Bao L, Wang J, Zhou M, Williams RW, Cui Y. Inferring gene transcriptional modulatory relations: a genetical genomics approach. Human Molecular Genetics. 14: 1119-25. PMID 15772094 DOI: 10.1093/hmg/ddi124  0.648
2005 Bystrykh L, Weersing E, Dontje B, Sutton S, Pletcher MT, Wiltshire T, Su AI, Vellenga E, Wang J, Manly KF, Lu L, Chesler EJ, Alberts R, Jansen RC, Williams RW, et al. Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nature Genetics. 37: 225-32. PMID 15711547 DOI: 10.1038/Ng1497  0.613
2005 Chesler EJ, Lu L, Shou S, Qu Y, Gu J, Wang J, Hsu HC, Mountz JD, Baldwin NE, Langston MA, Threadgill DW, Manly KF, Williams RW. Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nature Genetics. 37: 233-42. PMID 15711545 DOI: 10.1038/Ng1518  0.652
2005 Scott RE, White-Grindley E, Ruley HE, Chesler EJ, Williams RW. P2P-R expression is genetically coregulated with components of the translation machinery and with PUM2, a translational repressor that associates with the P2P-R mRNA. Journal of Cellular Physiology. 204: 99-105. PMID 15617101 DOI: 10.1002/Jcp.20263  0.46
2005 Carlborg O, De Koning DJ, Manly KF, Chesler E, Williams RW, Haley CS. Methodological aspects of the genetic dissection of gene expression. Bioinformatics (Oxford, England). 21: 2383-93. PMID 15613385 DOI: 10.1093/Bioinformatics/Bti241  0.587
2005 Chesler E, Lu L, Wang J, Manly K, Williams R. WebQTL: An Internet resource for the integrative genetic analysis of gene expression and pain related phenotypes The Journal of Pain. 6: S10. DOI: 10.1016/J.Jpain.2005.01.038  0.591
2004 Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, ... ... Chesler EJ, et al. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature Genetics. 36: 1133-7. PMID 15514660 DOI: 10.1038/Ng1104-1133  0.798
2004 Chesler EJ, Williams RW. Brain gene expression: genomics and genetics. International Review of Neurobiology. 60: 59-95. PMID 15474587 DOI: 10.1016/S0074-7742(04)60003-1  0.586
2004 Sternberg WF, Chesler EJ, Wilson SG, Mogil JS. Acute progesterone can recruit sex-specific neurochemical mechanisms mediating swim stress-induced and kappa-opioid analgesia in mice. Hormones and Behavior. 46: 467-73. PMID 15465533 DOI: 10.1016/J.Yhbeh.2004.05.007  0.653
2004 Kest B, Palmese CA, Juni A, Chesler EJ, Mogil JS. Mapping of a quantitative trait locus for morphine withdrawal severity. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 610-7. PMID 15457340 DOI: 10.1007/S00335-004-2367-3  0.591
2004 Jablonski MM, Lu L, Wang X, Chesler EJ, Carps E, Qi S, Gu J, Williams RW. The ldis1 lens mutation in RIIIS/J mice maps to chromosome 8 near cadherin 1. Molecular Vision. 10: 577-87. PMID 15343150  0.503
2004 Chesler EJ, Lu L, Wang J, Williams RW, Manly KF. WebQTL: rapid exploratory analysis of gene expression and genetic networks for brain and behavior. Nature Neuroscience. 7: 485-6. PMID 15114364 DOI: 10.1038/Nn0504-485  0.587
2003 Chesler EJ, Wang J, Lu L, Qu Y, Manly KF, Williams RW. Genetic correlates of gene expression in recombinant inbred strains: a relational model system to explore neurobehavioral phenotypes. Neuroinformatics. 1: 343-57. PMID 15043220 DOI: 10.1385/Ni:1:4:343  0.675
2003 Chesler EJ, Ritchie J, Kokayeff A, Lariviere WR, Wilson SG, Mogil JS. Genotype-dependence of gabapentin and pregabalin sensitivity: the pharmacogenetic mediation of analgesia is specific to the type of pain being inhibited. Pain. 106: 325-35. PMID 14659515 DOI: 10.1016/S0304-3959(03)00330-0  0.68
2003 Abiola O, Angel JM, Avner P, Bachmanov AA, Belknap JK, Bennett B, Blankenhorn EP, Blizard DA, Bolivar V, Brockmann GA, Buck KJ, Bureau JF, Casley WL, Chesler EJ, Cheverud JM, et al. The nature and identification of quantitative trait loci: a community's view. Nature Reviews. Genetics. 4: 911-6. PMID 14634638 DOI: 10.1038/Nrg1206  0.753
2003 Peirce JL, Chesler EJ, Williams RW, Lu L. Genetic architecture of the mouse hippocampus: identification of gene loci with selective regional effects. Genes, Brain, and Behavior. 2: 238-52. PMID 12953790 DOI: 10.1034/J.1601-183X.2003.00030.X  0.697
2003 Mogil JS, Wilson SG, Chesler EJ, Rankin AL, Nemmani KV, Lariviere WR, Groce MK, Wallace MR, Kaplan L, Staud R, Ness TJ, Glover TL, Stankova M, Mayorov A, Hruby VJ, et al. The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans. Proceedings of the National Academy of Sciences of the United States of America. 100: 4867-72. PMID 12663858 DOI: 10.1073/Pnas.0730053100  0.698
2003 Wilson SG, Bryant CD, Lariviere WR, Olsen MS, Giles BE, Chesler EJ, Mogil JS. The heritability of antinociception II: pharmacogenetic mediation of three over-the-counter analgesics in mice. The Journal of Pharmacology and Experimental Therapeutics. 305: 755-64. PMID 12606637 DOI: 10.1124/Jpet.102.047902  0.71
2003 Wilson SG, Smith SB, Chesler EJ, Melton KA, Haas JJ, Mitton B, Strasburg K, Hubert L, Rodriguez-Zas SL, Mogil JS. The heritability of antinociception: common pharmacogenetic mediation of five neurochemically distinct analgesics. The Journal of Pharmacology and Experimental Therapeutics. 304: 547-59. PMID 12538806 DOI: 10.1124/Jpet.102.041889  0.722
2002 Chesler EJ, Wilson SG, Lariviere WR, Rodriguez-Zas SL, Mogil JS. Identification and ranking of genetic and laboratory environment factors influencing a behavioral trait, thermal nociception, via computational analysis of a large data archive. Neuroscience and Biobehavioral Reviews. 26: 907-23. PMID 12667496 DOI: 10.1016/S0149-7634(02)00103-3  0.716
2002 Chesler EJ, Wilson SG, Lariviere WR, Rodriguez-Zas SL, Mogil JS. Influences of laboratory environment on behavior. Nature Neuroscience. 5: 1101-2. PMID 12403996 DOI: 10.1038/Nn1102-1101  0.647
2002 Wilson SG, Chesler EJ, Hain H, Rankin AJ, Schwarz JZ, Call SB, Murray MR, West EE, Teuscher C, Rodriguez-Zas S, Belknap JK, Mogil JS. Identification of quantitative trait loci for chemical/inflammatory nociception in mice. Pain. 96: 385-91. PMID 11973013 DOI: 10.1016/S0304-3959(01)00489-4  0.736
2001 Chesler EJ, Rodriguez-Zas SL, Mogil JS. In silico mapping of mouse quantitative trait loci. Science (New York, N.Y.). 294: 2423. PMID 11752534 DOI: 10.1126/Science.294.5551.2423A  0.562
2001 Lariviere WR, Chesler EJ, Mogil JS. Transgenic studies of pain and analgesia: mutation or background genotype? The Journal of Pharmacology and Experimental Therapeutics. 297: 467-73. PMID 11303031  0.519
2000 Mogil JS, Chesler EJ, Wilson SG, Juraska JM, Sternberg WF. Sex differences in thermal nociception and morphine antinociception in rodents depend on genotype. Neuroscience and Biobehavioral Reviews. 24: 375-89. PMID 10781697 DOI: 10.1016/S0149-7634(00)00015-4  0.681
1996 Chesler EJ, Salamone JD. Effects of acute and repeated clozapine injections on cholinomimetic-induced vacuous jaw movements. Pharmacology, Biochemistry, and Behavior. 54: 619-24. PMID 8743638 DOI: 10.1016/0091-3057(95)02280-5  0.406
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