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Kevin Talbot, M.D., D.Phil. - Publications

Affiliations: 
Physiology, Anatomy and Genetics University of Oxford, Oxford, United Kingdom 
Area:
Motor Neuron Degeneration
Website:
http://www.dpag.ox.ac.uk/academic_staff/kevin_talbot
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Year Citation  Score
2023 Vahsen BF, Nalluru S, Morgan GR, Farrimond L, Carroll E, Xu Y, Cramb KML, Amein B, Scaber J, Katsikoudi A, Candalija A, Carcolé M, Dafinca R, Isaacs AM, Wade-Martins R, ... ... Talbot K, et al. C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9. Nature Communications. 14: 5898. PMID 37736756 DOI: 10.1038/s41467-023-41603-0  0.37
2023 Christoforidou E, Simoes FA, Gordon D, Talbot K, Hafezparast M. Aberrant dynein function promotes TDP-43 aggregation and upregulation of p62 in male mice harboring transgenic human TDP-43. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-10. PMID 37498094 DOI: 10.1080/21678421.2023.2239276  0.408
2022 Chaytow H, Carroll E, Gordon D, Huang YT, van der Hoorn D, Smith HL, Becker T, Becker CG, Faller KME, Talbot K, Gillingwater TH. Targeting phosphoglycerate kinase 1 with terazosin improves motor neuron phenotypes in multiple models of amyotrophic lateral sclerosis. Ebiomedicine. 104202. PMID 35963713 DOI: 10.1016/j.ebiom.2022.104202  0.363
2022 Cooper-Knock J, Julian TH, Feneberg E, Highley JR, Sidra M, Turner MR, Talbot K, Ansorge O, Allen SP, Moll T, Shelkovnikova T, Castelli L, Hautbergue GM, Hewitt C, Kirby J, et al. Atypical TDP-43 protein expression in an ALS pedigree carrying a p.Y374X truncation mutation in TARDBP. Brain Pathology (Zurich, Switzerland). e13104. PMID 35871544 DOI: 10.1111/bpa.13104  0.417
2022 Vahsen BF, Gray E, Candalija A, Cramb KML, Scaber J, Dafinca R, Katsikoudi A, Xu Y, Farrimond L, Wade-Martins R, James WS, Turner MR, Cowley SA, Talbot K. Human iPSC co-culture model to investigate the interaction between microglia and motor neurons. Scientific Reports. 12: 12606. PMID 35871163 DOI: 10.1038/s41598-022-16896-8  0.395
2022 Pandya S, Maia PD, Freeze B, Menke RAL, Talbot K, Turner MR, Raj A. Modeling seeding and neuroanatomic spread of pathology in amyotrophic lateral sclerosis. Neuroimage. 251: 118968. PMID 35143975 DOI: 10.1016/j.neuroimage.2022.118968  0.329
2022 Dharmadasa T, Scaber J, Edmond E, Marsden R, Thompson A, Talbot K, Turner MR. Genetic testing in motor neurone disease. Practical Neurology. PMID 35027459 DOI: 10.1136/practneurol-2021-002989  0.365
2022 Giacomelli E, Vahsen BF, Calder EL, Xu Y, Scaber J, Gray E, Dafinca R, Talbot K, Studer L. Human stem cell models of neurodegeneration: From basic science of amyotrophic lateral sclerosis to clinical translation. Cell Stem Cell. 29: 11-35. PMID 34995492 DOI: 10.1016/j.stem.2021.12.008  0.315
2021 Johnson JO, Chia R, Miller DE, Li R, Kumaran R, Abramzon Y, Alahmady N, Renton AE, Topp SD, Gibbs JR, Cookson MR, Sabir MS, Dalgard CL, Troakes C, Jones AR, ... ... Talbot K, et al. Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis. Jama Neurology. PMID 34459874 DOI: 10.1001/jamaneurol.2021.2598  0.616
2021 Vahsen BF, Gray E, Thompson AG, Ansorge O, Anthony DC, Cowley SA, Talbot K, Turner MR. Non-neuronal cells in amyotrophic lateral sclerosis - from pathogenesis to biomarkers. Nature Reviews. Neurology. PMID 33927394 DOI: 10.1038/s41582-021-00487-8  0.341
2020 Feneberg E, Charles PD, Finelli MJ, Scott C, Kessler BM, Fischer R, Ansorge O, Gray E, Talbot K, Turner MR. Detection and Quantification of Novel C-terminal TDP-43 Fragments in ALS-TDP. Brain Pathology (Zurich, Switzerland). e12923. PMID 33300249 DOI: 10.1111/bpa.12923  0.719
2020 Herrando-Grabulosa M, Casas C, Talbot K, Aguilera J. Neurotrophic Properties of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Motor Neuron Disease. Toxins. 12. PMID 33096857 DOI: 10.3390/toxins12100666  0.326
2020 Opie-Martin S, Ossher L, Bredin A, Kulka A, Pearce N, Talbot K, Al-Chalabi A. Motor Neuron Disease Register for England, Wales and Northern Ireland-an analysis of incidence in England. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-8. PMID 32940088 DOI: 10.1080/21678421.2020.1812661  0.3
2020 Sathyaprakash C, Manzano R, Varela MA, Hashimoto Y, Wood MJA, Talbot K, Aoki Y. Development of LNA Gapmer Oligonucleotide-Based Therapy for ALS/FTD Caused by the C9orf72 Repeat Expansion. Methods in Molecular Biology (Clifton, N.J.). 2176: 185-208. PMID 32865792 DOI: 10.1007/978-1-0716-0771-8_14  0.502
2020 Thompson AG, Gray E, Mäger I, Thézénas ML, Charles PD, Talbot K, Fischer R, Kessler BM, Wood M, Turner MR. CSF extracellular vesicle proteomics demonstrates altered protein homeostasis in amyotrophic lateral sclerosis. Clinical Proteomics. 17: 31. PMID 32821252 DOI: 10.1186/S12014-020-09294-7  0.384
2020 Feneberg E, Gordon D, Thompson AG, Finelli MJ, Dafinca R, Candalija A, Charles PD, Mäger I, Wood MJ, Fischer R, Kessler BM, Gray E, Turner MR, Talbot K. An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress. Neurobiology of Disease. 105050. PMID 32800996 DOI: 10.1016/J.Nbd.2020.105050  0.801
2020 Prudencio M, Humphrey J, Pickles S, Brown AL, Hill SE, Kachergus J, Shi J, Heckman M, Spiegel M, Cook C, Song Y, Yue M, Daughrity L, Carlomagno Y, Jansen-West K, ... ... Talbot K, et al. Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia. The Journal of Clinical Investigation. PMID 32790644 DOI: 10.1172/Jci139741  0.383
2020 Feneberg E, Turner MR, Ansorge O, Talbot K. Amyotrophic lateral sclerosis with a heterozygous D91A SOD1 variant and classical ALS-TDP neuropathology. Neurology. PMID 32769137 DOI: 10.1212/Wnl.0000000000010587  0.377
2020 Gray E, Thompson AG, Wuu J, Pelt J, Talbot K, Benatar M, Turner MR. CSF chitinases before and after symptom onset in amyotrophic lateral sclerosis. Annals of Clinical and Translational Neurology. PMID 32666680 DOI: 10.1002/Acn3.51114  0.342
2020 Talbot K. Amyotrophic Lateral Sclerosis: network vulnerability and monosynaptic connections. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 32665325 DOI: 10.1136/Jnnp-2020-323729  0.464
2020 Nolan M, Scott C, Gamarallage MP, Lunn D, Carpenter K, McDonough E, Meyer D, Kaanumalle S, Santamaria-Pang A, Turner MR, Talbot K, Ansorge O. Quantitative patterns of motor cortex proteinopathy across ALS genotypes. Acta Neuropathologica Communications. 8: 98. PMID 32616036 DOI: 10.1186/S40478-020-00961-2  0.491
2020 Kelly M, Lavrov A, Garcia-Gancedo L, Parr J, Hart R, Chiwera T, Shaw CE, Al-Chalabi A, Marsden R, Turner MR, Talbot K. The use of biotelemetry to explore disease progression markers in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-11. PMID 32573278 DOI: 10.1080/21678421.2020.1773501  0.338
2020 Ababneh NA, Scaber J, Flynn R, Douglas A, Barbagallo P, Candalija A, Turner MR, Sims D, Dafinca R, Cowley SA, Talbot K. Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair. Human Molecular Genetics. PMID 32504093 DOI: 10.1093/Hmg/Ddaa106  0.473
2020 Dafinca R, Barbagallo P, Farrimond L, Candalija A, Scaber J, Ababneh NA, Sathyaprakash C, Vowles J, Cowley SA, Talbot K. Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD. Stem Cell Reports. PMID 32330447 DOI: 10.1016/J.Stemcr.2020.03.023  0.391
2020 Turner MR, Talbot K. Primary lateral sclerosis: diagnosis and management. Practical Neurology. PMID 32217663 DOI: 10.1136/Practneurol-2019-002300  0.463
2020 Sleigh JN, Tosolini AP, Gordon D, Devoy A, Fratta P, Fisher EMC, Talbot K, Schiavo G. Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes. Cell Reports. 30: 3655-3662.e2. PMID 32187538 DOI: 10.1016/J.Celrep.2020.02.078  0.813
2020 Tu S, Wang C, Menke RAL, Talbot K, Barnett M, Kiernan MC, Turner MR. Regional callosal integrity and bilaterality of limb weakness in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-7. PMID 32106716 DOI: 10.1080/21678421.2020.1733020  0.363
2020 Carling PJ, Mortiboys H, Green C, Mihaylov S, Sandor C, Schwartzentruber A, Taylor R, Wei W, Hastings C, Wong S, Lo C, Evetts S, Clemmens H, Wyles M, Willcox S, ... ... Talbot K, et al. Deep phenotyping of peripheral tissue facilitates mechanistic disease stratification in sporadic Parkinson's disease. Progress in Neurobiology. 101772. PMID 32058042 DOI: 10.1016/J.Pneurobio.2020.101772  0.35
2019 Oprişoreanu AM, Smith HL, Arya S, Webster R, Zhong Z, Wehner D, Cardozo MJ, Becker T, Talbot K, Becker CG. Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation. Cell Reports. 29: 1082-1098.e10. PMID 31665626 DOI: 10.1016/J.Celrep.2019.09.033  0.386
2019 Williamson MG, Finelli MJ, Sleigh JN, Reddington A, Gordon D, Talbot K, Davies KE, Oliver PL. Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo. Human Molecular Genetics. PMID 31642482 DOI: 10.1093/Hmg/Ddz190  0.817
2019 Turner MR, Faull C, McDermott CJ, Nickol AH, Palmer J, Talbot K. Tracheostomy in motor neurone disease. Practical Neurology. PMID 31273080 DOI: 10.1136/Practneurol-2018-002109  0.433
2019 Thompson AG, Gray E, Bampton A, Raciborska D, Talbot K, Turner MR. CSF chitinase proteins in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 31123140 DOI: 10.1136/Jnnp-2019-320442  0.32
2019 Young CA, Ealing J, McDermott C, Williams T, Al-Chalabi A, Majeed T, Burke G, Pinto A, Dick D, Talbot K, Harrower T, Walsh J, Chandran S, Hanemann CO, Mills R, et al. The relationships between symptoms, disability, perceived health and quality of life in amyotrophic lateral sclerosis/motor neuron disease. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-11. PMID 31116037 DOI: 10.1080/21678421.2019.1615951  0.346
2019 Allen SP, Hall B, Castelli LM, Francis L, Woof R, Siskos AP, Kouloura E, Gray E, Thompson AG, Talbot K, Higginbottom A, Myszczynska M, Allen CF, Stopford MJ, Hemingway J, et al. Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. PMID 30698736 DOI: 10.1093/Brain/Awy353  0.417
2019 Tu S, Menke RAL, Talbot K, Kiernan MC, Turner MR. Cerebellar tract alterations in PLS and ALS. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-4. PMID 30663900 DOI: 10.1080/21678421.2018.1562554  0.447
2019 Robertson J, Gray E, Thompson A, Feneberg E, Talbot K, Turner M. 004 A triaging blood test for neurology? Serum neurofilament levels in a cohort of GP referrals Journal of Neurology, Neurosurgery, and Psychiatry. 90. DOI: 10.1136/Jnnp-2019-Abn-2.38  0.354
2019 Edmond EC, Menke R, Proudfoot M, Talbot K, Stagg CJ, Turner MR. Motor System Biomarkers In Amyotrophic Lateral Sclerosis Journal of Neurology, Neurosurgery, and Psychiatry. 90. DOI: 10.1136/Jnnp-2019-Abn-2.213  0.405
2018 Gordon D, Dafinca R, Scaber J, Alegre-Abarrategui J, Farrimond L, Scott C, Biggs D, Kent L, Oliver PL, Davies B, Ansorge O, Wade-Martins R, Talbot K. Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction. Neurobiology of Disease. PMID 30290270 DOI: 10.1016/J.Nbd.2018.09.024  0.753
2018 Wong MMK, Hoekstra SD, Vowles J, Watson LM, Fuller G, Németh AH, Cowley SA, Ansorge O, Talbot K, Becker EBE. Neurodegeneration in SCA14 is associated with increased PKCγ kinase activity, mislocalization and aggregation. Acta Neuropathologica Communications. 6: 99. PMID 30249303 DOI: 10.1186/S40478-018-0600-7  0.404
2018 Talbot K, Feneberg E, Scaber J, Thompson AG, Turner MR. Amyotrophic lateral sclerosis: the complex path to precision medicine. Journal of Neurology. PMID 30054789 DOI: 10.1007/S00415-018-8983-8  0.45
2018 Tu S, Menke RAL, Talbot K, Kiernan MC, Turner MR. Regional thalamic MRI as a marker of widespread cortical pathology and progressive frontotemporal involvement in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 30049750 DOI: 10.1136/Jnnp-2018-318625  0.346
2018 de Majo M, Topp SD, Smith BN, Nishimura AL, Chen HJ, Gkazi AS, Miller J, Wong CH, Vance C, Baas F, Ten Asbroek ALMA, Kenna KP, Ticozzi N, Redondo AG, Esteban-Pérez J, ... ... Talbot K, et al. ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function. Neurobiology of Aging. PMID 30033073 DOI: 10.1016/J.Neurobiolaging.2018.06.015  0.357
2018 Salter M, Corfield E, Ramadass A, Grand F, Green J, Westra J, Lim CR, Farrimond L, Feneberg E, Scaber J, Thompson A, Ossher L, Turner M, Talbot K, Cudkowicz M, et al. Initial Identification of a Blood-Based Chromosome Conformation Signature for Aiding in the Diagnosis of Amyotrophic Lateral Sclerosis. Ebiomedicine. PMID 29941342 DOI: 10.1016/J.Ebiom.2018.06.015  0.368
2018 Proudfoot M, van Ede F, Quinn A, Colclough GL, Wuu J, Talbot K, Benatar M, Woolrich MW, Nobre AC, Turner MR. Impaired corticomuscular and interhemispheric cortical beta oscillation coupling in amyotrophic lateral sclerosis. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. PMID 29678369 DOI: 10.1016/J.Clinph.2018.03.019  0.347
2018 Proudfoot M, Colclough GL, Quinn A, Wuu J, Talbot K, Benatar M, Nobre AC, Woolrich MW, Turner MR. Increased cerebral functional connectivity in ALS: A resting-state magnetoencephalography study. Neurology. 90: e1418-e1424. PMID 29661904 DOI: 10.1212/Wnl.0000000000005333  0.337
2018 Westeneng HJ, Debray TPA, Visser AE, van Eijk RPA, Rooney JPK, Calvo A, Martin S, McDermott CJ, Thompson AG, Pinto S, Kobeleva X, Rosenbohm A, Stubendorff B, Sommer H, Middelkoop BM, ... ... Talbot K, et al. Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model. The Lancet. Neurology. PMID 29598923 DOI: 10.1016/S1474-4422(18)30089-9  0.4
2018 Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, ... ... Talbot K, et al. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 97: 1268-1283.e6. PMID 29566793 DOI: 10.1016/J.Neuron.2018.02.027  0.695
2018 Milinis K, Tennant A, Mills RJ, Al-Chalabi A, Burke G, Dick DJ, Ealing J, Hanemann CO, Harrower T, McDermott CJ, Majeed T, Pinto A, Talbot K, Williams T, Young CA, et al. Development and validation of Spasticity Index-Amyotrophic Lateral Sclerosis. Acta Neurologica Scandinavica. PMID 29468643 DOI: 10.1111/Ane.12910  0.347
2018 Feneberg E, Gray E, Ansorge O, Talbot K, Turner MR. Towards a TDP-43-Based Biomarker for ALS and FTLD. Molecular Neurobiology. PMID 29460270 DOI: 10.1007/S12035-018-0947-6  0.444
2018 Groen EJN, Talbot K, Gillingwater TH. Advances in therapy for spinal muscular atrophy: promises and challenges. Nature Reviews. Neurology. PMID 29422644 DOI: 10.1038/Nrneurol.2018.4  0.487
2018 Benoy V, Van Helleputte L, Prior R, d'Ydewalle C, Haeck W, Geens N, Scheveneels W, Schevenels B, Cader MZ, Talbot K, Kozikowski AP, Vanden Berghe P, Van Damme P, Robberecht W, Van Den Bosch L. HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease. Brain : a Journal of Neurology. PMID 29415205 DOI: 10.1093/Brain/Awx375  0.386
2018 Keogh MJ, Wei W, Aryaman J, Wilson I, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, Al Sarraj S, Morris CM, Ansorge O, Pickering-Brown S, Jones N, et al. Oligogenic genetic variation of neurodegenerative disease genes in 980 postmortem human brains. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 29332010 DOI: 10.1136/Jnnp-2017-317234  0.348
2018 Thompson AG, Gray E, Thézénas ML, Charles PD, Evetts S, Hu MT, Talbot K, Fischer R, Kessler BM, Turner MR. Cerebrospinal fluid macrophage biomarkers in amyotrophic lateral sclerosis. Annals of Neurology. PMID 29331073 DOI: 10.1002/Ana.25143  0.381
2018 Menke RAL, Proudfoot M, Talbot K, Turner MR. The two-year progression of structural and functional cerebral MRI in amyotrophic lateral sclerosis. Neuroimage. Clinical. 17: 953-961. PMID 29321969 DOI: 10.1016/J.Nicl.2017.12.025  0.313
2017 Wood MJA, Talbot K, Bowerman M. Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape. Human Molecular Genetics. 26: R151-R159. PMID 28977438 DOI: 10.1093/Hmg/Ddx215  0.487
2017 Al-Chalabi A, Andersen PM, Chandran S, Chio A, Corcia P, Couratier P, Danielsson O, de Carvalho M, Desnuelle C, Grehl T, Grosskreutz J, Holmøy T, Ingre C, Karlsborg M, Kleveland G, ... ... Talbot K, et al. July 2017 ENCALS statement on edaravone. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-4. PMID 28975816 DOI: 10.1080/21678421.2017.1369125  0.401
2017 Bowerman M, Becker CG, Yáñez-Muñoz RJ, Ning K, Wood MJA, Gillingwater TH, Talbot K. Therapeutic strategies for spinal muscular atrophy: SMN and beyond. Disease Models & Mechanisms. 10: 943-954. PMID 28768735 DOI: 10.1242/Dmm.030148  0.493
2017 Talbot K, Tizzano EF. The clinical landscape for SMA in a new therapeutic era. Gene Therapy. PMID 28644430 DOI: 10.1038/Gt.2017.52  0.453
2017 Turner MR, Al-Chalabi A, Chio A, Hardiman O, Kiernan MC, Rohrer JD, Rowe J, Seeley W, Talbot K. Genetic screening in sporadic ALS and FTD. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 28642287 DOI: 10.1136/Jnnp-2017-315995  0.371
2017 Christie-Brown V, Mitchell J, Talbot K. The SMA Trust: the role of a disease-focused research charity in developing treatments for SMA. Gene Therapy. PMID 28561814 DOI: 10.1038/Gt.2017.47  0.41
2017 Smith BN, Topp SD, Fallini C, Shibata H, Chen HJ, Troakes C, King A, Ticozzi N, Kenna KP, Soragia-Gkazi A, Miller JW, Sato A, Dias DM, Jeon M, Vance C, ... ... Talbot K, et al. Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis. Science Translational Medicine. 9. PMID 28469040 DOI: 10.1126/Scitranslmed.Aad9157  0.474
2017 Sleigh JN, Dawes JM, West SJ, Wei N, Spaulding EL, Gómez-Martín A, Zhang Q, Burgess RW, Cader MZ, Talbot K, Yang XL, Bennett DL, Schiavo G. Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations. Proceedings of the National Academy of Sciences of the United States of America. PMID 28351971 DOI: 10.1073/Pnas.1614557114  0.809
2017 Aoki Y, Manzano R, Lee Y, Dafinca R, Aoki M, Douglas AG, Varela MA, Sathyaprakash C, Scaber J, Barbagallo P, Vader P, Mäger I, Ezzat K, Turner MR, Ito N, ... ... Talbot K, et al. C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia. Brain : a Journal of Neurology. PMID 28334866 DOI: 10.1016/S0960-8966(17)30312-7  0.425
2017 Douglas AG, Andreoletti G, Talbot K, Hammans SR, Singh J, Whitney A, Ennis S, Foulds NC. ADCY5-related dyskinesia presenting as familial myoclonus-dystonia. Neurogenetics. PMID 28229249 DOI: 10.1007/S10048-017-0510-Z  0.342
2017 Wei W, Keogh MJ, Wilson I, Coxhead J, Ryan S, Rollinson S, Griffin H, Kurzawa-Akinibi M, Santibanez-Koref M, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, et al. Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains. Acta Neuropathologica Communications. 5: 13. PMID 28153046 DOI: 10.1186/S40478-016-0404-6  0.361
2017 Sandor C, Honti F, Haerty W, Szewczyk-Krolikowski K, Tomlinson P, Evetts S, Millin S, Keane T, McCarthy SA, Durbin R, Talbot K, Hu M, Webber C, Ponting CP, Wade-Martins R. Whole-exome sequencing of 228 patients with sporadic Parkinson's disease. Scientific Reports. 7: 41188. PMID 28117402 DOI: 10.1038/Srep41188  0.339
2017 Thompson AG, Blackwell V, Marsden R, Millard E, Lawson C, Nickol AH, East JE, Talbot K, Allan PJ, Turner MR. A risk stratifying tool to facilitate safe late-stage percutaneous endoscopic gastrostomy in ALS. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-6. PMID 28100064 DOI: 10.1080/21678421.2016.1274330  0.327
2017 Turner MR, Talbot K. Sweet food preference in amyotrophic lateral sclerosis. Practical Neurology. PMID 28073920 DOI: 10.1136/Practneurol-2016-001554  0.329
2017 Talbot K. 1825 Anti-sense treatment in sma: a landmark in the therapy of motor neuron diseases Journal of Neurology, Neurosurgery, and Psychiatry. 88. DOI: 10.1136/Jnnp-2017-Abn.37  0.487
2017 Lim CR, Goh KJ, Phan YX, Patel J, Shahrizaila N, Loh EC, Ng WF, Capelle DP, Hunter E, Salter M, Elvidge W, Ramadass A, Green J, Kent L, Ossher L, ... ... Talbot K, et al. Epigenetic signatures and early detection of neurodegenerative diseases: Development of stratifying biomarkers for amyotrophic lateral sclerosis in Asian cohorts Journal of the Neurological Sciences. 381: 616-616. DOI: 10.1016/J.Jns.2017.08.1736  0.319
2016 Keogh MJ, Wei W, Wilson I, Coxhead J, Ryan S, Rollinson S, Griffin H, Kurzawa-Akanbi M, Santibanez-Koref M, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, et al. Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource. Genome Research. PMID 28003435 DOI: 10.1101/Gr.210609.116  0.3
2016 Scaber J, Talbot K. What is the role of TDP-43 in C9orf72-related amyotrophic lateral sclerosis and frontemporal dementia? Brain : a Journal of Neurology. 139: 3057-3059. PMID 27913405 DOI: 10.1093/Brain/Aww264  0.411
2016 Abdel-Khalik J, Yutuc E, Crick PJ, Gustafsson JÅ, Warner M, Roman G, Talbot K, Gray E, Griffiths WJ, Turner MR, Wang Y. Defective cholesterol metabolism in amyotrophic lateral sclerosis. Journal of Lipid Research. PMID 27811233 DOI: 10.1194/Jlr.P071639  0.315
2016 Turner MR, Goldacre R, Talbot K, Goldacre MJ. Psychiatric disorders prior to amyotrophic lateral sclerosis. Annals of Neurology. PMID 27761925 DOI: 10.1002/Ana.24801  0.331
2016 Proudfoot M, Rohenkohl G, Quinn A, Colclough GL, Wuu J, Talbot K, Woolrich MW, Benatar M, Nobre AC, Turner MR. Altered cortical beta-band oscillations reflect motor system degeneration in amyotrophic lateral sclerosis. Human Brain Mapping. PMID 27623516 DOI: 10.1002/Hbm.23357  0.414
2016 Hammond SM, Hazell G, Shabanpoor F, Saleh AF, Bowerman M, Sleigh JN, Meijboom KE, Zhou H, Muntoni F, Talbot K, Gait MJ, Wood MJ. Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America. PMID 27621445 DOI: 10.1073/Pnas.1605731113  0.797
2016 Nolan M, Talbot K, Ansorge O. Pathogenesis of FUS-associated ALS and FTD: insights from rodent models. Acta Neuropathologica Communications. 4: 99. PMID 27600654 DOI: 10.1186/S40478-016-0358-8  0.423
2016 Kenna KP, van Doormaal PT, Dekker AM, Ticozzi N, Kenna BJ, Diekstra FP, van Rheenen W, van Eijk KR, Jones AR, Keagle P, Shatunov A, Sproviero W, Smith BN, van Es MA, Topp SD, ... ... Talbot K, et al. NEK1 variants confer susceptibility to amyotrophic lateral sclerosis. Nature Genetics. PMID 27455347 DOI: 10.1038/Ng.3626  0.415
2016 Marsden R, Allan P, Blackwell V, East J, Lawson C, Nickol AH, Millard E, Talbot K, Thompson AG, Turner MR. Nutritional pathway for people with motor neurone disease. British Journal of Community Nursing. 21: 360-3. PMID 27401201 DOI: 10.12968/Bjcn.2016.21.7.360  0.391
2016 Talbot K. Clinical tool for predicting survival in ALS: do we need one? Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27378084 DOI: 10.1136/Jnnp-2016-313683  0.346
2016 McDermott CJ, Bradburn MJ, Maguire C, Cooper CL, Baird WO, Baxter SK, Cohen J, Cantrill H, Dixon S, Ackroyd R, Baudouin S, Bentley A, Berrisford R, Bianchi S, Bourke SC, ... ... Talbot K, et al. DiPALS: Diaphragm Pacing in patients with Amyotrophic Lateral Sclerosis - a randomised controlled trial. Health Technology Assessment (Winchester, England). 20: 1-186. PMID 27353839 DOI: 10.3310/Hta20450  0.332
2016 Thompson AG, Gray E, Heman-Ackah SM, Mäger I, Talbot K, Andaloussi SE, Wood MJ, Turner MR. Extracellular vesicles in neurodegenerative disease - pathogenesis to biomarkers. Nature Reviews. Neurology. PMID 27174238 DOI: 10.1038/Nrneurol.2016.68  0.328
2016 Dafinca R, Scaber J, Ababneh N, Lalic T, Weir G, Christian H, Vowles J, Douglas AG, Fletcher-Jones A, Browne C, Nakanishi M, Turner MR, Wade-Martins R, Cowley SA, Talbot K. C9orf72 Hexanucleotide Expansions are Associated with Altered ER Calcium Homeostasis and Stress Granule Formation in iPSC-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Stem Cells (Dayton, Ohio). PMID 27097283 DOI: 10.1002/Stem.2388  0.516
2016 Fernandes HJ, Hartfield EM, Christian HC, Emmanoulidou E, Zheng Y, Booth H, Bogetofte H, Lang C, Ryan BJ, Sardi SP, Badger J, Vowles J, Evetts S, Tofaris GK, Vekrellis K, ... Talbot K, et al. ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons. Stem Cell Reports. PMID 26905200 DOI: 10.1016/J.Stemcr.2016.01.013  0.385
2016 Menke RA, Proudfoot M, Wuu J, Andersen PM, Talbot K, Benatar M, Turner MR. Increased functional connectivity common to symptomatic amyotrophic lateral sclerosis and those at genetic risk. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 26733601 DOI: 10.1136/Jnnp-2015-311945  0.372
2016 Aoki Y, Manzano R, Takeda S, Talbot K, Wood M. 741. Development of LNA Gapmer Oligonucleotide Based Therapy for FTD/ALS Caused by the C9orf72 Repeat Expansion Molecular Therapy. 24: S292. DOI: 10.1016/S1525-0016(16)33549-3  0.452
2016 Proudfoot M, Rohenkohl G, Gould I, Wuu J, Andersen PM, Talbot K, Woolrich MW, Benatar M, Nobre AC, Turner MR. Changes in cortical β-oscillation dynamics across the clinical spectrum of motor neuron disease The Lancet. 387: S84. DOI: 10.1016/S0140-6736(16)00471-2  0.463
2015 Somers E, Lees RD, Hoban K, Sleigh JN, Zhou H, Muntoni F, Talbot K, Gillingwater TH, Parson SH. Vascular defects and spinal cord hypoxia in spinal muscular atrophy. Annals of Neurology. PMID 26506088 DOI: 10.1002/Ana.24549  0.816
2015 Simon NG, Huynh W, Vucic S, Talbot K, Kiernan MC. Motor neuron disease: current management and future prospects. Internal Medicine Journal. 45: 1005-13. PMID 26429216 DOI: 10.1111/Imj.12874  0.485
2015 Menke RA, Gray E, Lu CH, Kuhle J, Talbot K, Malaspina A, Turner MR. CSF neurofilament light chain reflects corticospinal tract degeneration in ALS. Annals of Clinical and Translational Neurology. 2: 748-55. PMID 26273687 DOI: 10.1002/Acn3.212  0.381
2015 Turner MR, Goldacre R, Talbot K, Goldacre MJ. Cerebrovascular injury as a risk factor for amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 26260352 DOI: 10.1136/Jnnp-2015-311157  0.318
2015 McDermott CJ, Bradburn MJ, Maguire C, Cooper CL, Baird WO, Baxter SK, Bourke SC, Imam I, Bentley A, Ealing J, Elliott M, Hanemann CO, Hughes P, ... ... Talbot K, et al. Safety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): a multicentre, open-label, randomised controlled trial. The Lancet. Neurology. 14: 883-92. PMID 26234554 DOI: 10.1016/S1474-4422(15)00152-0  0.314
2015 Gray E, Larkin JR, Claridge TD, Talbot K, Sibson NR, Turner MR. The longitudinal cerebrospinal fluid metabolomic profile of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-8. PMID 26121274 DOI: 10.3109/21678421.2015.1053490  0.361
2015 Grice SJ, Sleigh JN, Motley WW, Liu JL, Burgess RW, Talbot K, Cader MZ. Dominant, toxic gain-of-function mutations in gars lead to non-cell autonomous neuropathology. Human Molecular Genetics. 24: 4397-406. PMID 25972375 DOI: 10.1093/Hmg/Ddv176  0.817
2015 Lu CH, Macdonald-Wallis C, Gray E, Pearce N, Petzold A, Norgren N, Giovannoni G, Fratta P, Sidle K, Fish M, Orrell R, Howard R, Talbot K, Greensmith L, Kuhle J, et al. Neurofilament light chain: A prognostic biomarker in amyotrophic lateral sclerosis. Neurology. 84: 2247-57. PMID 25934855 DOI: 10.1212/Wnl.0000000000001642  0.352
2015 Tomlinson PR, Zheng Y, Fischer R, Heidasch R, Gardiner C, Evetts S, Hu M, Wade-Martins R, Turner MR, Morris J, Talbot K, Kessler BM, Tofaris GK. Identification of distinct circulating exosomes in Parkinson's disease. Annals of Clinical and Translational Neurology. 2: 353-61. PMID 25909081 DOI: 10.1002/Acn3.175  0.333
2015 Mutihac R, Alegre-Abarrategui J, Gordon D, Farrimond L, Yamasaki-Mann M, Talbot K, Wade-Martins R. TARDBP pathogenic mutations increase cytoplasmic translocation of TDP-43 and cause reduction of endoplasmic reticulum Ca²⁺ signaling in motor neurons. Neurobiology of Disease. 75: 64-77. PMID 25526708 DOI: 10.1016/J.Nbd.2014.12.010  0.421
2015 Mutihac R, Ababneh N, Scaber J, Wade-Martins R, Cowley S, Talbot K. Modelling amyotrophic lateral sclerosis (ALS) using mutant and CAS9/CRISPR-corrected motor neurons from patients with C9ORF72 mutations reveals disease-specific cellular phenotypes Journal of the Neurological Sciences. 357. DOI: 10.1016/J.Jns.2015.08.198  0.545
2014 Smith BN, Ticozzi N, Fallini C, Gkazi AS, Topp S, Kenna KP, Scotter EL, Kost J, Keagle P, Miller JW, Calini D, Vance C, Danielson EW, Troakes C, Tiloca C, ... ... Talbot K, et al. Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS. Neuron. 84: 324-31. PMID 25374358 DOI: 10.1016/J.Neuron.2014.09.027  0.408
2014 Talbot K, Vincent A. Advances in the clinical science of the motor unit: from motor neuron to neuromuscular junction. Current Opinion in Neurology. 27: 503-5. PMID 25159932 DOI: 10.1097/Wco.0000000000000139  0.428
2014 Menke RA, Körner S, Filippini N, Douaud G, Knight S, Talbot K, Turner MR. Widespread grey matter pathology dominates the longitudinal cerebral MRI and clinical landscape of amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 137: 2546-55. PMID 24951638 DOI: 10.1093/Brain/Awu162  0.404
2014 Kent L, Vizard TN, Smith BN, Topp SD, Vance C, Gkazi A, Miller J, Shaw CE, Talbot K. Autosomal dominant inheritance of rapidly progressive amyotrophic lateral sclerosis due to a truncation mutation in the fused in sarcoma (FUS) gene. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 15: 557-62. PMID 24899262 DOI: 10.3109/21678421.2014.920033  0.45
2014 Bäumer D, East SZ, Tseu B, Zeman A, Hilton D, Talbot K, Ansorge O. FTLD-ALS of TDP-43 type and SCA2 in a family with a full ataxin-2 polyglutamine expansion. Acta Neuropathologica. 128: 597-604. PMID 24718895 DOI: 10.1007/S00401-014-1277-Z  0.436
2014 Bäumer D, Talbot K, Turner MR. Advances in motor neurone disease. Journal of the Royal Society of Medicine. 107: 14-21. PMID 24399773 DOI: 10.1177/0141076813511451  0.537
2014 Sleigh JN, Grice SJ, Burgess RW, Talbot K, Cader MZ. Neuromuscular junction maturation defects precede impaired lower motor neuron connectivity in Charcot-Marie-Tooth type 2D mice. Human Molecular Genetics. 23: 2639-50. PMID 24368416 DOI: 10.1093/Hmg/Ddt659  0.814
2014 Feigin A, Talbot K. Expanding the genetics of huntingtonism. Neurology. 82: 286-7. PMID 24363136 DOI: 10.1212/Wnl.0000000000000067  0.351
2014 Bäumer D, Butterworth R, Menke RA, Talbot K, Hofer M, Turner MR. Progressive hemiparesis (Mills syndrome) with aphasia in amyotrophic lateral sclerosis. Neurology. 82: 457-8. PMID 24363135 DOI: 10.1212/Wnl.0000000000000090  0.483
2014 Turner BJ, Alfazema N, Sheean RK, Sleigh JN, Davies KE, Horne MK, Talbot K. Overexpression of survival motor neuron improves neuromuscular function and motor neuron survival in mutant SOD1 mice. Neurobiology of Aging. 35: 906-15. PMID 24210254 DOI: 10.1016/J.Neurobiolaging.2013.09.030  0.831
2014 Rolinski M, Szewczyk-Krolikowski K, Tomlinson PR, Nithi K, Talbot K, Ben-Shlomo Y, Hu MT. REM sleep behaviour disorder is associated with worse quality of life and other non-motor features in early Parkinson's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 85: 560-6. PMID 24187013 DOI: 10.1136/Jnnp-2013-306104  0.351
2014 Szewczyk-Krolikowski K, Tomlinson P, Nithi K, Wade-Martins R, Talbot K, Ben-Shlomo Y, Hu MT. The influence of age and gender on motor and non-motor features of early Parkinson's disease: initial findings from the Oxford Parkinson Disease Center (OPDC) discovery cohort. Parkinsonism & Related Disorders. 20: 99-105. PMID 24183678 DOI: 10.1016/J.Parkreldis.2013.09.025  0.368
2014 Sleigh JN, Barreiro-Iglesias A, Oliver PL, Biba A, Becker T, Davies KE, Becker CG, Talbot K. Chondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophy. Human Molecular Genetics. 23: 855-69. PMID 24067532 DOI: 10.1093/Hmg/Ddt477  0.823
2014 Talbot K. Amyotrophic lateral sclerosis: cell vulnerability or system vulnerability? Journal of Anatomy. 224: 45-51. PMID 24010870 DOI: 10.1111/Joa.12107  0.442
2014 Talbot K. Should all patients with ALS have genetic testing? Journal of Neurology, Neurosurgery, and Psychiatry. 85: 475. PMID 23868948 DOI: 10.1136/Jnnp-2013-305727  0.376
2013 Németh AH, Kwasniewska AC, Lise S, Parolin Schnekenberg R, Becker EB, Bera KD, Shanks ME, Gregory L, Buck D, Zameel Cader M, Talbot K, de Silva R, Fletcher N, Hastings R, Jayawant S, et al. Next generation sequencing for molecular diagnosis of neurological disorders using ataxias as a model. Brain : a Journal of Neurology. 136: 3106-18. PMID 24030952 DOI: 10.1093/Brain/Awt236  0.661
2013 Turner MR, Goldacre R, Ramagopalan S, Talbot K, Goldacre MJ. Autoimmune disease preceding amyotrophic lateral sclerosis: an epidemiologic study. Neurology. 81: 1222-5. PMID 23946298 DOI: 10.1212/Wnl.0B013E3182A6Cc13  0.371
2013 Halpin L, Savulescu J, Talbot K, Turner M, Talman P. Improving access to medicines: empowering patients in the quest to improve treatment for rare lethal diseases. Journal of Medical Ethics. PMID 23839261 DOI: 10.1136/Medethics-2013-101427  0.345
2013 Kolind S, Sharma R, Knight S, Johansen-Berg H, Talbot K, Turner MR. Myelin imaging in amyotrophic and primary lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 562-73. PMID 23678852 DOI: 10.3109/21678421.2013.794843  0.397
2013 Hobson EV, McGeachan A, Al-Chalabi A, Chandran S, Crawley F, Dick D, Donaghy C, Ealing J, Ellis CM, Gorrie G, Hanemann CO, Harrower T, Jung A, Majeed T, Malaspina A, ... ... Talbot K, et al. Management of sialorrhoea in motor neuron disease: a survey of current UK practice. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 521-7. PMID 23647474 DOI: 10.3109/21678421.2013.790452  0.394
2013 Turner MR, Talbot K. Mimics and chameleons in motor neurone disease. Practical Neurology. 13: 153-64. PMID 23616620 DOI: 10.1136/Practneurol-2013-000557  0.419
2013 Kayadjanian N, Burghes A, Finkel RS, Mercuri E, Rouault F, Schwersenz I, Talbot K. SMA-EUROPE workshop report: Opportunities and challenges in developing clinical trials for spinal muscular atrophy in Europe. Orphanet Journal of Rare Diseases. 8: 44. PMID 23514578 DOI: 10.1186/1750-1172-8-44  0.329
2013 Morrison KE, Dhariwal S, Hornabrook R, Savage L, Burn DJ, Khoo TK, Kelly J, Murphy CL, Al-Chalabi A, Dougherty A, Leigh PN, Wijesekera L, Thornhill M, Ellis CM, ... ... Talbot K, et al. Lithium in patients with amyotrophic lateral sclerosis (LiCALS): a phase 3 multicentre, randomised, double-blind, placebo-controlled trial. The Lancet. Neurology. 12: 339-45. PMID 23453347 DOI: 10.1016/S1474-4422(13)70037-1  0.351
2013 Stamelou M, Adams M, Davagnanam I, Batla A, Sheerin U, Talbot K, Bhatia KP. Progressive ataxia and palatal tremor associated with dense pontine calcification: A unique case. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 1155-7. PMID 23436739 DOI: 10.1002/Mds.25310  0.363
2013 Turner MR, Hardiman O, Benatar M, Brooks BR, Chio A, de Carvalho M, Ince PG, Lin C, Miller RG, Mitsumoto H, Nicholson G, Ravits J, Shaw PJ, Swash M, Talbot K, et al. Controversies and priorities in amyotrophic lateral sclerosis. The Lancet. Neurology. 12: 310-22. PMID 23415570 DOI: 10.1016/S1474-4422(13)70036-X  0.632
2013 Kent L, Davies P, Kennett R, Wimalaratna S, Kerr R, Turner MR, Talbot K. Unmasking of incipient amyotrophic lateral sclerosis by botulinum toxin therapy. Journal of Neurology. 260: 1166-7. PMID 23400499 DOI: 10.1007/S00415-013-6854-X  0.408
2013 Sleigh JN, Grice SJ, Davies KE, Talbot K. Spinal muscular atrophy at the crossroads of basic science and therapy. Neuromuscular Disorders : Nmd. 23: 96. PMID 22981697 DOI: 10.1016/J.Nmd.2012.08.008  0.811
2013 Vester A, Velez-Ruiz G, McLaughlin HM, Lupski JR, Talbot K, Vance JM, Züchner S, Roda RH, Fischbeck KH, Biesecker LG, Nicholson G, Beg AA, Antonellis A. A loss-of-function variant in the human histidyl-tRNA synthetase (HARS) gene is neurotoxic in vivo. Human Mutation. 34: 191-9. PMID 22930593 DOI: 10.1002/Humu.22210  0.414
2012 Turner MR, Talbot K. Motor neurone disease is a clinical diagnosis. Practical Neurology. 12: 396-7. PMID 23144309 DOI: 10.1136/Practneurol-2012-000374  0.444
2012 McDermott CJ, Maguire C, Cooper CL, Ackroyd R, Baird WO, Baudouin S, Bentley A, Bianchi S, Bourke S, Bradburn MJ, Dixon S, Ealing J, Galloway S, Karat D, Maynard N, ... ... Talbot K, et al. Protocol for diaphragm pacing in patients with respiratory muscle weakness due to motor neurone disease (DiPALS): a randomised controlled trial. Bmc Neurology. 12: 74. PMID 22897892 DOI: 10.1186/1471-2377-12-74  0.396
2012 Hoffman EP, Talbot K. A calm before the exome storm: coming together of dSMA and CMT2. Neurology. 78: 1706-7. PMID 22459684 DOI: 10.1212/Wnl.0B013E3182556C1F  0.426
2012 Majounie E, Renton AE, Mok K, Dopper EG, Waite A, Rollinson S, Chiò A, Restagno G, Nicolaou N, Simon-Sanchez J, van Swieten JC, Abramzon Y, Johnson JO, Sendtner M, Pamphlett R, ... ... Talbot K, et al. Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study. The Lancet. Neurology. 11: 323-30. PMID 22406228 DOI: 10.1016/S1474-4422(12)70043-1  0.588
2012 Evans MC, Modo M, Talbot K, Sibson N, Turner MR. Magnetic resonance imaging of pathological processes in rodent models of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 13: 288-301. PMID 22117132 DOI: 10.3109/17482968.2011.623300  0.394
2012 Turner MR, Wotton C, Talbot K, Goldacre MJ. Cardiovascular fitness as a risk factor for amyotrophic lateral sclerosis: indirect evidence from record linkage study. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 395-8. PMID 22072701 DOI: 10.1136/Jnnp-2011-301161  0.329
2012 McLaughlin HM, Sakaguchi R, Giblin W, Wilson TE, Biesecker L, Lupski JR, Talbot K, Vance JM, Züchner S, Lee YC, Kennerson M, Hou YM, Nicholson G, Antonellis A. A recurrent loss-of-function alanyl-tRNA synthetase (AARS) mutation in patients with Charcot-Marie-Tooth disease type 2N (CMT2N). Human Mutation. 33: 244-53. PMID 22009580 DOI: 10.1002/Humu.21635  0.401
2012 Turner M, Wotton C, Talbot K, Goldacre MJ. 1118 Are MND patients pre-morbidly fitter? Indirect evidence from hospital record-linkage Journal of Neurology, Neurosurgery & Psychiatry. 83: e1.90-e1. DOI: 10.1136/Jnnp-2011-301993.18  0.302
2011 Motley WW, Seburn KL, Nawaz MH, Miers KE, Cheng J, Antonellis A, Green ED, Talbot K, Yang XL, Fischbeck KH, Burgess RW. Charcot-Marie-Tooth-linked mutant GARS is toxic to peripheral neurons independent of wild-type GARS levels. Plos Genetics. 7: e1002399. PMID 22144914 DOI: 10.1371/Journal.Pgen.1002399  0.705
2011 Gibbons CJ, Mills RJ, Thornton EW, Ealing J, Mitchell JD, Shaw PJ, Talbot K, Tennant A, Young CA. Development of a patient reported outcome measure for fatigue in motor neurone disease: the Neurological Fatigue Index (NFI-MND). Health and Quality of Life Outcomes. 9: 101. PMID 22107756 DOI: 10.1186/1477-7525-9-101  0.324
2011 Douaud G, Filippini N, Knight S, Talbot K, Turner MR. Integration of structural and functional magnetic resonance imaging in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 134: 3470-9. PMID 22075069 DOI: 10.1093/Brain/Awr279  0.334
2011 Talbot K. Familial versus sporadic amyotrophic lateral sclerosis--a false dichotomy? Brain : a Journal of Neurology. 134: 3429-31. PMID 22051609 DOI: 10.1093/Brain/Awr296  0.396
2011 Kwok AS, Phadwal K, Turner BJ, Oliver PL, Raw A, Simon AK, Talbot K, Agashe VR. HspB8 mutation causing hereditary distal motor neuropathy impairs lysosomal delivery of autophagosomes. Journal of Neurochemistry. 119: 1155-61. PMID 21985219 DOI: 10.1111/J.1471-4159.2011.07521.X  0.715
2011 Mutsaers CA, Wishart TM, Lamont DJ, Riessland M, Schreml J, Comley LH, Murray LM, Parson SH, Lochmüller H, Wirth B, Talbot K, Gillingwater TH. Reversible molecular pathology of skeletal muscle in spinal muscular atrophy. Human Molecular Genetics. 20: 4334-44. PMID 21840928 DOI: 10.1093/Hmg/Ddr360  0.405
2011 Sharma R, Hicks S, Berna CM, Kennard C, Talbot K, Turner MR. Oculomotor dysfunction in amyotrophic lateral sclerosis: a comprehensive review. Archives of Neurology. 68: 857-61. PMID 21747027 DOI: 10.1001/Archneurol.2011.130  0.422
2011 Sleigh JN, Gillingwater TH, Talbot K. The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy. Disease Models & Mechanisms. 4: 457-67. PMID 21708901 DOI: 10.1242/Dmm.007245  0.833
2011 Turner MR, Wicks P, Brownstein CA, Massagli MP, Toronjo M, Talbot K, Al-Chalabi A. Concordance between site of onset and limb dominance in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. 82: 853-4. PMID 20562391 DOI: 10.1136/Jnnp.2010.208413  0.407
2011 Talbot K. S.I.2 Motor neuron disorders and vulnerability to RNA processing Neuromuscular Disorders. 21: 680. DOI: 10.1016/J.Nmd.2011.06.888  0.383
2010 Talbot K. Do twin studies still have anything to teach us about the genetics of amyotrophic lateral sclerosis? Journal of Neurology, Neurosurgery, and Psychiatry. 81: 1299-300. PMID 21087924 DOI: 10.1136/Jnnp.2010.224816  0.411
2010 Filippini N, Douaud G, Mackay CE, Knight S, Talbot K, Turner MR. Corpus callosum involvement is a consistent feature of amyotrophic lateral sclerosis. Neurology. 75: 1645-52. PMID 21041787 DOI: 10.1212/Wnl.0B013E3181Fb84D1  0.469
2010 McLaughlin HM, Sakaguchi R, Liu C, Igarashi T, Pehlivan D, Chu K, Iyer R, Cruz P, Cherukuri PF, Hansen NF, Mullikin JC, Biesecker LG, Wilson TE, Ionasescu V, ... ... Talbot K, et al. Compound heterozygosity for loss-of-function lysyl-tRNA synthetase mutations in a patient with peripheral neuropathy. American Journal of Human Genetics. 87: 560-6. PMID 20920668 DOI: 10.1016/J.Ajhg.2010.09.008  0.425
2010 Wishart TM, Huang JP, Murray LM, Lamont DJ, Mutsaers CA, Ross J, Geldsetzer P, Ansorge O, Talbot K, Parson SH, Gillingwater TH. SMN deficiency disrupts brain development in a mouse model of severe spinal muscular atrophy. Human Molecular Genetics. 19: 4216-28. PMID 20705736 DOI: 10.1093/Hmg/Ddq340  0.457
2010 Bäumer D, Hilton D, Paine SM, Turner MR, Lowe J, Talbot K, Ansorge O. Juvenile ALS with basophilic inclusions is a FUS proteinopathy with FUS mutations. Neurology. 75: 611-8. PMID 20668261 DOI: 10.1212/Wnl.0B013E3181Ed9Cde  0.481
2010 Bäumer D, Ansorge O, Almeida M, Talbot K. The role of RNA processing in the pathogenesis of motor neuron degeneration. Expert Reviews in Molecular Medicine. 12: e21. PMID 20642879 DOI: 10.1017/S1462399410001523  0.527
2010 Turner MR, Scaber J, Goodfellow JA, Lord ME, Marsden R, Talbot K. The diagnostic pathway and prognosis in bulbar-onset amyotrophic lateral sclerosis. Journal of the Neurological Sciences. 294: 81-5. PMID 20452624 DOI: 10.1016/J.Jns.2010.03.028  0.363
2010 Southgate L, Dafou D, Hoyle J, Li N, Kinning E, Critchley P, Németh AH, Talbot K, Bindu PS, Sinha S, Taly AB, Raghavendra S, Müller F, Maher ER, Trembath RC. Novel SPG11 mutations in Asian kindreds and disruption of spatacsin function in the zebrafish. Neurogenetics. 11: 379-89. PMID 20390432 DOI: 10.1007/S10048-010-0243-8  0.389
2010 Murray LM, Talbot K, Gillingwater TH. Review: neuromuscular synaptic vulnerability in motor neurone disease: amyotrophic lateral sclerosis and spinal muscular atrophy. Neuropathology and Applied Neurobiology. 36: 133-56. PMID 20202121 DOI: 10.1111/J.1365-2990.2010.01061.X  0.47
2010 Motley WW, Talbot K, Fischbeck KH. GARS axonopathy: not every neuron's cup of tRNA. Trends in Neurosciences. 33: 59-66. PMID 20152552 DOI: 10.1016/J.Tins.2009.11.001  0.7
2010 Turner BJ, Ackerley S, Davies KE, Talbot K. Dismutase-competent SOD1 mutant accumulation in myelinating Schwann cells is not detrimental to normal or transgenic ALS model mice. Human Molecular Genetics. 19: 815-24. PMID 20008901 DOI: 10.1093/Hmg/Ddp550  0.725
2010 Turner MR, Brockington A, Scaber J, Hollinger H, Marsden R, Shaw PJ, Talbot K. Pattern of spread and prognosis in lower limb-onset ALS. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 11: 369-73. PMID 20001488 DOI: 10.3109/17482960903420140  0.349
2010 Murray LM, Lee S, Bäumer D, Parson SH, Talbot K, Gillingwater TH. Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy. Human Molecular Genetics. 19: 420-33. PMID 19884170 DOI: 10.1093/Hmg/Ddp506  0.526
2010 Turner MR, Abisgold J, Yeates DG, Talbot K, Goldacre MJ. Head and other physical trauma requiring hospitalisation is not a significant risk factor in the development of ALS. Journal of the Neurological Sciences. 288: 45-8. PMID 19878957 DOI: 10.1016/J.Jns.2009.10.010  0.316
2010 Pereira EA, Turner MR, Wass JA, Talbot K. Reduction of elevated IGF-1 levels in coincident amyotrophic lateral sclerosis and acromegaly. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 11: 255-7. PMID 19634028 DOI: 10.3109/17482960902870985  0.405
2010 Talbot K, Lowe J, Ansorge O, Hilton D, Baumer D, Paine S, Turner M. PATU5 Characterisation of fused in sarcoma pathology and FUS mutations in juvenile amyotrophic lateral sclerosis with basophilic inclusions Journal of Neurology, Neurosurgery & Psychiatry. 81: e25-e25. DOI: 10.1136/Jnnp.2010.226340.34  0.474
2010 Talbot K, Turner MR. PORT02 Oxford motor neurone disorders research Journal of Neurology, Neurosurgery, and Psychiatry. 81. DOI: 10.1136/Jnnp.2010.226340.197  0.458
2010 Hu M, Ponting C, Mackay C, Talbot K, Wade-Martins R, Wood M, Bolam JP, Ben-Shlomo Y, Ansorge O, James W. POMD09 Understanding the early pathological pathways in Parkinson's disease. The Oxford Parkinson's Disease Centre Journal of Neurology, Neurosurgery & Psychiatry. 81: e59-e59. DOI: 10.1136/Jnnp.2010.226340.169  0.317
2010 Filippini N, Douaud G, Mackay CE, Knight S, Talbot K, Turner MR. PATH44 Corpus callosum diffusion tensor imaging as a biomarker for motor neurone disease Journal of Neurology, Neurosurgery & Psychiatry. 81: e19-e20. DOI: 10.1136/Jnnp.2010.226340.12  0.413
2010 Filippini N, Mackay C, Douaud G, Knight S, Talbot K, Turner M. P89 An MRI biomarker for motor neuron disease? Neuromuscular Disorders. 20: S29. DOI: 10.1016/S0960-8966(10)70104-8  0.437
2009 Bäumer D, Lee S, Nicholson G, Davies JL, Parkinson NJ, Murray LM, Gillingwater TH, Ansorge O, Davies KE, Talbot K. Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy. Plos Genetics. 5: e1000773. PMID 20019802 DOI: 10.1371/Journal.Pgen.1000773  0.753
2009 Bäumer D, Parkinson N, Talbot K. TARDBP in amyotrophic lateral sclerosis: identification of a novel variant but absence of copy number variation. Journal of Neurology, Neurosurgery, and Psychiatry. 80: 1283-5. PMID 19864663 DOI: 10.1136/Jnnp.2008.166512  0.494
2009 Talbot K. Motor neuron disease: the bare essentials. Practical Neurology. 9: 303-9. PMID 19762894 DOI: 10.1136/Jnnp.2009.188151  0.515
2009 Talbot K. Another gene for ALS: mutations in sporadic cases and the rare variant hypothesis. Neurology. 73: 1172-3. PMID 19741213 DOI: 10.1212/Wnl.0B013E3181Bd1161  0.48
2009 Achilli F, Bros-Facer V, Williams HP, Banks GT, AlQatari M, Chia R, Tucci V, Groves M, Nickols CD, Seburn KL, Kendall R, Cader MZ, Talbot K, van Minnen J, Burgess RW, et al. An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. Disease Models & Mechanisms. 2: 359-73. PMID 19470612 DOI: 10.1242/Dmm.002527  0.462
2009 Turner BJ, Parkinson NJ, Davies KE, Talbot K. Survival motor neuron deficiency enhances progression in an amyotrophic lateral sclerosis mouse model. Neurobiology of Disease. 34: 511-7. PMID 19332122 DOI: 10.1016/J.Nbd.2009.03.005  0.771
2009 Chiò A, Schymick JC, Restagno G, Scholz SW, Lombardo F, Lai SL, Mora G, Fung HC, Britton A, Arepalli S, Gibbs JR, Nalls M, Berger S, Kwee LC, Oddone EZ, ... ... Talbot K, et al. A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. Human Molecular Genetics. 18: 1524-32. PMID 19193627 DOI: 10.1093/Hmg/Ddp059  0.792
2009 Turner MR, Kiernan MC, Leigh PN, Talbot K. Biomarkers in amyotrophic lateral sclerosis. The Lancet. Neurology. 8: 94-109. PMID 19081518 DOI: 10.1016/S1474-4422(08)70293-X  0.425
2009 Ciccarelli O, Behrens TE, Johansen-Berg H, Talbot K, Orrell RW, Howard RS, Nunes RG, Miller DH, Matthews PM, Thompson AJ, Smith SM. Investigation of white matter pathology in ALS and PLS using tract-based spatial statistics. Human Brain Mapping. 30: 615-24. PMID 18172851 DOI: 10.1002/Hbm.20527  0.412
2008 Baumer D, Flossmann E, Cudlip S, Quaghebeur G, Jeans A, Talbot K. Primary angiitis of the CNS mimicking a spinal cord tumour. Journal of Neurology. 255: 1970-2. PMID 19165530 DOI: 10.1007/S00415-009-0853-Y  0.302
2008 Turner BJ, Bäumer D, Parkinson NJ, Scaber J, Ansorge O, Talbot K. TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy. Bmc Neuroscience. 9: 104. PMID 18957104 DOI: 10.1186/1471-2202-9-104  0.537
2008 Doran G, Davies KE, Talbot K. Activation of mutant protein kinase Cgamma leads to aberrant sequestration and impairment of its cellular function. Biochemical and Biophysical Research Communications. 372: 447-53. PMID 18503760 DOI: 10.1016/J.Bbrc.2008.05.072  0.668
2008 Talbot K, Davies KE. Is good housekeeping the key to motor neuron survival? Cell. 133: 572-4. PMID 18485864 DOI: 10.1016/J.Cell.2008.05.002  0.75
2008 Parkinson NJ, Baumer D, Rose-Morris A, Talbot K. Candidate screening of the bovine and feline spinal muscular atrophy genes reveals no evidence for involvement in human motor neuron disorders. Neuromuscular Disorders : Nmd. 18: 394-7. PMID 18395445 DOI: 10.1016/J.Nmd.2008.03.003  0.535
2008 James PA, Rankin J, Talbot K. Asymmetrical late onset motor neuropathy associated with a novel mutation in the small heat shock protein HSPB1 (HSP27). Journal of Neurology, Neurosurgery, and Psychiatry. 79: 461-3. PMID 18344398 DOI: 10.1136/Jnnp.2007.125179  0.464
2008 Turner BJ, Talbot K. Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS. Progress in Neurobiology. 85: 94-134. PMID 18282652 DOI: 10.1016/J.Pneurobio.2008.01.001  0.507
2008 Murray LM, Comley LH, Thomson D, Parkinson N, Talbot K, Gillingwater TH. Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy. Human Molecular Genetics. 17: 949-62. PMID 18065780 DOI: 10.1093/Hmg/Ddm367  0.427
2007 Talbot K, Davies KE. Chapter 7 Spinal muscular atrophies and hereditary motor neuropathies. Handbook of Clinical Neurology. 82: 141-53. PMID 18808892 DOI: 10.1016/S0072-9752(07)80010-8  0.746
2007 Turner MR, Chohan G, Quaghebeur G, Greenhall RC, Hadjivassiliou M, Talbot K. A case of celiac disease mimicking amyotrophic lateral sclerosis. Nature Clinical Practice. Neurology. 3: 581-4. PMID 17914346 DOI: 10.1038/Ncpneuro0631  0.315
2007 Schymick JC, Talbot K, Traynor BJ. Genetics of sporadic amyotrophic lateral sclerosis. Human Molecular Genetics. 16: R233-42. PMID 17911166 DOI: 10.1093/Hmg/Ddm215  0.814
2007 Talbot K. The study of rare diseases: butterfly collecting or an entrée to understanding common conditions? Practical Neurology. 7: 210-1. PMID 17636135 DOI: 10.1136/Jnnp.2007.124396  0.305
2007 Cader MZ, Ren J, James PA, Bird LE, Talbot K, Stammers DK. Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy. Febs Letters. 581: 2959-64. PMID 17544401 DOI: 10.1016/J.Febslet.2007.05.046  0.365
2006 James PA, Cader MZ, Muntoni F, Childs AM, Crow YJ, Talbot K. Severe childhood SMA and axonal CMT due to anticodon binding domain mutations in the GARS gene. Neurology. 67: 1710-2. PMID 17101916 DOI: 10.1212/01.Wnl.0000242619.52335.Bc  0.429
2006 Talbot K, Ansorge O. Recent advances in the genetics of amyotrophic lateral sclerosis and frontotemporal dementia: common pathways in neurodegenerative disease. Human Molecular Genetics. 15: R182-7. PMID 16987882 DOI: 10.1093/Hmg/Ddl202  0.441
2006 James PA, Talbot K. The molecular genetics of non-ALS motor neuron diseases. Biochimica Et Biophysica Acta. 1762: 986-1000. PMID 16765570 DOI: 10.1016/J.Bbadis.2006.04.003  0.534
2006 Ackerley S, James PA, Kalli A, French S, Davies KE, Talbot K. A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes. Human Molecular Genetics. 15: 347-54. PMID 16368711 DOI: 10.1093/Hmg/Ddi452  0.733
2004 Evgrafov OV, Mersiyanova I, Irobi J, Van Den Bosch L, Dierick I, Leung CL, Schagina O, Verpoorten N, Van Impe K, Fedotov V, Dadali E, Auer-Grumbach M, Windpassinger C, Wagner K, Mitrovic Z, ... ... Talbot K, et al. Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. Nature Genetics. 36: 602-6. PMID 15122254 DOI: 10.1038/Ng1354  0.434
2004 Irobi J, Van Impe K, Seeman P, Jordanova A, Dierick I, Verpoorten N, Michalik A, De Vriendt E, Jacobs A, Van Gerwen V, Vennekens K, Mazanec R, Tournev I, Hilton-Jones D, Talbot K, et al. Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy. Nature Genetics. 36: 597-601. PMID 15122253 DOI: 10.1038/Ng1328  0.402
2004 Talbot K. Motor neuron disease Medicine. 32: 105-107. DOI: 10.1383/Medc.32.11.105.53361  0.484
2004 Talbot K. Monomelic amyotrophy or Hirayama's disease Practical Neurology. 4: 362-365. DOI: 10.1111/J.1474-7766.2004.00265.X  0.417
2003 Anderson K, Talbot K. Spinal muscular atrophies reveal motor neuron vulnerability to defects in ribonucleoprotein handling. Current Opinion in Neurology. 16: 595-9. PMID 14501843 DOI: 10.1097/01.Wco.0000093102.34793.13  0.511
2003 Talbot K, Davies K. Musculoskeletal diseases: from complex genetics to therapy. Current Opinion in Pharmacology. 3: 277-9. PMID 12810192 DOI: 10.1016/S1471-4892(03)00044-4  0.63
2002 Talbot K. Motor neurone disease. Postgraduate Medical Journal. 78: 513-9. PMID 12357010 DOI: 10.1136/Pmj.78.923.513  0.492
2001 Talbot K, Davies KE. Spinal muscular atrophy. Seminars in Neurology. 21: 189-97. PMID 11442327 DOI: 10.1055/S-2001-15264  0.751
2001 Skordis LA, Dunckley MG, Burglen L, Campbell L, Talbot K, Patel S, Melki J, Davies KE, Dubowitz V, Muntoni F. Characterisation of novel point mutations in the survival motor neuron gene SMN, in three patients with SMA. Human Genetics. 108: 356-7. PMID 11379882 DOI: 10.1007/S004390100497  0.723
1999 Talbot K. Spinal muscular atrophy. Journal of Inherited Metabolic Disease. 22: 545-54. PMID 10407786 DOI: 10.1023/A:1005516625866  0.42
1998 Talbot K, Miguel-Aliaga I, Mohaghegh P, Ponting CP, Davies KE. Characterization of a gene encoding survival motor neuron (SMN)-related protein, a constituent of the spliceosome complex. Human Molecular Genetics. 7: 2149-56. PMID 9817934 DOI: 10.1093/Hmg/7.13.2149  0.708
1997 Talbot K. What's new in the molecular genetics of spinal muscular atrophy? European Journal of Paediatric Neurology : Ejpn : Official Journal of the European Paediatric Neurology Society. 1: 149-55. PMID 10728211 DOI: 10.1016/S1090-3798(97)80051-7  0.311
1997 Nesbit MA, Hodges MD, Campbell L, de Meulemeester TM, Alders M, Rodrigues NR, Talbot K, Theodosiou AM, Mannens MA, Nakamura Y, Little PF, Davies KE. Genomic organization and chromosomal localization of a member of the MAP kinase phosphatase gene family to human chromosome 11p15.5 and a pseudogene to 10q11.2. Genomics. 42: 284-94. PMID 9192849 DOI: 10.1006/Geno.1997.4737  0.627
1997 Talbot K, Rodrigues NR, Ignatius J, Muntoni F, Davies KE. Gene conversion at the SMN locus in autosomal recessive spinal muscular atrophy does not predict a mild phenotype. Neuromuscular Disorders : Nmd. 7: 198-201. PMID 9185185 DOI: 10.1016/S0960-8966(97)00450-1  0.739
1997 Talbot K, Ponting CP, Theodosiou AM, Rodrigues NR, Surtees R, Mountford R, Davies KE. Missense mutation clustering in the survival motor neuron gene: a role for a conserved tyrosine and glycine rich region of the protein in RNA metabolism? Human Molecular Genetics. 6: 497-500. PMID 9147655 DOI: 10.1093/Hmg/6.3.497  0.736
1996 Talbot K, Rodrigues N, Bernert G, Bittner R, Davies K. Evidence for compound heterozygosity causing mild and severe forms of autosomal recessive spinal muscular atrophy. Journal of Medical Genetics. 33: 1019-21. PMID 9004135 DOI: 10.1136/Jmg.33.12.1019  0.737
1996 Rodrigues NR, Owen N, Talbot K, Patel S, Muntoni F, Ignatius J, Dubowitz V, Davies KE. Gene deletions in spinal muscular atrophy. Journal of Medical Genetics. 33: 93-6. PMID 8929942 DOI: 10.1136/Jmg.33.2.93  0.684
1996 Rodrigues NR, Talbot K, Davies KE. Molecular genetics of autosomal recessive spinal muscular atrophy. Molecular Medicine (Cambridge, Mass.). 2: 400-4. PMID 8827710 DOI: 10.1007/Bf03401899  0.662
1995 Rodrigues NR, Owen N, Talbot K, Ignatius J, Dubowitz V, Davies KE. Deletions in the survival motor neuron gene on 5q13 in autosomal recessive spinal muscular atrophy. Human Molecular Genetics. 4: 631-4. PMID 7633412 DOI: 10.1093/Hmg/4.4.631  0.75
Low-probability matches (unlikely to be authored by this person)
2017 Fabes J, Matthews L, Filippini N, Talbot K, Jenkinson M, Turner MR. Quantitative FLAIR MRI in Amyotrophic Lateral Sclerosis. Academic Radiology. PMID 28572001 DOI: 10.1016/J.Acra.2017.04.008  0.3
2020 Shefner JM, Al-Chalabi A, Baker MR, Cui LY, de Carvalho M, Eisen A, Grosskreutz J, Hardiman O, Henderson R, Manuel Matamala J, Mitsumoto H, Paulus W, Simon N, Swash M, Talbot K, et al. A proposal for new diagnostic criteria for ALS. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. PMID 32387049 DOI: 10.1016/J.Clinph.2020.04.005  0.298
2014 Akimoto C, Volk AE, van Blitterswijk M, Van den Broeck M, Leblond CS, Lumbroso S, Camu W, Neitzel B, Onodera O, van Rheenen W, Pinto S, Weber M, Smith B, Proven M, Talbot K, et al. A blinded international study on the reliability of genetic testing for GGGGCC-repeat expansions in C9orf72 reveals marked differences in results among 14 laboratories. Journal of Medical Genetics. 51: 419-24. PMID 24706941 DOI: 10.1136/Jmedgenet-2014-102360  0.298
2022 Burley S, Beccano-Kelly DA, Talbot K, Llana OC, Wade-Martins R. Hyperexcitability in young iPSC-derived C9ORF72 mutant motor neurons is associated with increased intracellular calcium release. Scientific Reports. 12: 7378. PMID 35513421 DOI: 10.1038/s41598-022-09751-3  0.297
2016 McGeachan AJ, Hobson EV, Al-Chalabi A, Stephenson J, Chandran S, Crawley F, Dick D, Donaghy C, Ellis CM, Gorrie G, Hanemann OC, Harrower T, Jung A, Malaspina A, Morrison KE, ... ... Talbot K, et al. A multicentre evaluation of oropharyngeal secretion management practices in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-9. PMID 27579520 DOI: 10.1080/21678421.2016.1221433  0.295
2014 Evans MC, Serres S, Khrapitchev AA, Stolp HB, Anthony DC, Talbot K, Turner MR, Sibson NR. T₂-weighted MRI detects presymptomatic pathology in the SOD1 mouse model of ALS. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 785-93. PMID 24496176 DOI: 10.1038/Jcbfm.2014.19  0.293
2019 Garcia-Gancedo L, Kelly ML, Lavrov A, Parr J, Hart R, Marsden R, Turner MR, Talbot K, Chiwera T, Shaw CE, Al-Chalabi A. Objectively Monitoring Amyotrophic Lateral Sclerosis Patient Symptoms During Clinical Trials With Sensors: Observational Study. Jmir Mhealth and Uhealth. 7: e13433. PMID 31859676 DOI: 10.2196/13433  0.29
2012 Menke RA, Abraham I, Thiel CS, Filippini N, Knight S, Talbot K, Turner MR. Fractional anisotropy in the posterior limb of the internal capsule and prognosis in amyotrophic lateral sclerosis. Archives of Neurology. 69: 1493-9. PMID 22910997 DOI: 10.1001/Archneurol.2012.1122  0.289
2018 Salter M, Westra W, Hunter E, Elvidge W, Ramadass A, Grand F, Green J, Ossher L, Thompson A, Scaber J, Feneberg E, Turner M, Talbot K, Cudkowicz M, Akoulitchev A. A chromosomal conformation signature for a priori prediction of ALS progression subtypes F1000research. 7. DOI: 10.7490/F1000Research.1115185.1  0.287
2021 Winkelsas AM, Grunseich C, Harmison GG, Chwalenia K, Rinaldi C, Hammond SM, Johnson K, Bowerman M, Arya S, Talbot K, Wood MJ, Fischbeck KH. Targeting the 5' untranslated region of as a therapeutic strategy for spinal muscular atrophy. Molecular Therapy. Nucleic Acids. 23: 731-742. PMID 33575118 DOI: 10.1016/j.omtn.2020.12.027  0.285
2015 Proudfoot M, Menke RA, Sharma R, Berna CM, Hicks SL, Kennard C, Talbot K, Turner MR. Eye-tracking in amyotrophic lateral sclerosis: A longitudinal study of saccadic and cognitive tasks. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-11. PMID 26312652 DOI: 10.3109/21678421.2015.1054292  0.284
2016 Abdel-Khalik J, Yutuc E, Crick PJ, Gustafsson J, Warner M, Roman G, Talbot K, Gray E, Turner MR, Griffiths WJ, Wang Y. Evidence of defective cholesterol metabolism in ALS F1000research. 5. DOI: 10.7490/F1000Research.1113547.1  0.283
2024 Young CA, Chaouch A, Mcdermott CJ, Al-Chalabi A, Chhetri SK, Talbot K, Harrower T, Orrell RW, Annadale J, Hanemann OC, Scalfari A, Tennant A, Mills R. Dyspnea (breathlessness) in amyotrophic lateral sclerosis/motor neuron disease: prevalence, progression, severity, and correlates. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-11. PMID 38465877 DOI: 10.1080/21678421.2024.2322545  0.281
2019 Talbot K, Wood MJA. Wrangling RNA: Antisense oligonucleotides for neurological disorders. Science Translational Medicine. 11. PMID 31554737 DOI: 10.1126/Scitranslmed.Aay2069  0.278
2004 Aslam A, Misbah SA, Talbot K, Chapel H. Vitamin E deficiency induced neurological disease in common variable immunodeficiency: two cases and a review of the literature of vitamin E deficiency. Clinical Immunology (Orlando, Fla.). 112: 24-9. PMID 15207778 DOI: 10.1016/J.Clim.2004.02.001  0.277
2017 Carling P, Mortiboys H, Mihaylov S, Clemmens H, Schwartzenhuber A, Wade-Martins R, Talbot K, Hu M, Bandmann O. PO076 Disease stratification in sporadic parkinson’s disease Journal of Neurology, Neurosurgery, and Psychiatry. 88. DOI: 10.1136/Jnnp-2017-Abn.108  0.277
2020 Young CA, Mills R, Al-Chalabi A, Burke G, Chandran S, Dick DJ, Ealing J, Hanemann CO, Harrower T, Mcdermott CJ, Majeed T, Pinto A, Talbot K, Walsh J, Williams TL, et al. Measuring quality of life in ALS/MND: validation of the WHOQOL-BREF. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-9. PMID 32597226 DOI: 10.1080/21678421.2020.1752244  0.276
2011 Gibbons CJ, Mills RJ, Thornton EW, Ealing J, Mitchell JD, Shaw PJ, Talbot K, Tennant A, Young CA. Rasch analysis of the hospital anxiety and depression scale (HADS) for use in motor neurone disease. Health and Quality of Life Outcomes. 9: 82. PMID 21955749 DOI: 10.1186/1477-7525-9-82  0.276
2013 Stagg CJ, Knight S, Talbot K, Jenkinson M, Maudsley AA, Turner MR. Whole-brain magnetic resonance spectroscopic imaging measures are related to disability in ALS. Neurology. 80: 610-5. PMID 23325907 DOI: 10.1212/Wnl.0B013E318281Ccec  0.275
2013 Hicks SL, Sharma R, Khan AN, Berna CM, Waldecker A, Talbot K, Kennard C, Turner MR. An eye-tracking version of the trail-making test. Plos One. 8: e84061. PMID 24367626 DOI: 10.1371/Journal.Pone.0084061  0.275
2016 Proudfoot M, Jones A, Talbot K, Al-Chalabi A, Turner MR. The ALSFRS as an outcome measure in therapeutic trials and its relationship to symptom onset. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-12. PMID 26864085 DOI: 10.3109/21678421.2016.1140786  0.275
2002 Talbot K, Wright M, Keeling D. Normal d-dimer levels do not exclude the diagnosis of cerebral venous sinus thrombosis. Journal of Neurology. 249: 1603-4. PMID 12532928 DOI: 10.1007/S00415-002-0893-Z  0.275
2021 Altman T, Ionescu A, Ibraheem A, Priesmann D, Gradus-Pery T, Farberov L, Alexandra G, Shelestovich N, Dafinca R, Shomron N, Rage F, Talbot K, Ward ME, Dori A, Krüger M, et al. Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins. Nature Communications. 12: 6914. PMID 34824257 DOI: 10.1038/s41467-021-27221-8  0.275
2014 Xu Q, Evetts S, Hu M, Talbot K, Wade-Martins R, Davis JJ. An impedimetric assay of α-synuclein autoantibodies in early stage Parkinson's disease Rsc Advances. 4: 58773-58777. DOI: 10.1039/C4Ra10100F  0.275
2014 Menke RA, Szewczyk-Krolikowski K, Jbabdi S, Jenkinson M, Talbot K, Mackay CE, Hu M. Comprehensive morphometry of subcortical grey matter structures in early-stage Parkinson's disease. Human Brain Mapping. 35: 1681-90. PMID 23861334 DOI: 10.1002/Hbm.22282  0.274
2013 Gibbons C, Thornton E, Ealing J, Shaw P, Talbot K, Tennant A, Young C. The impact of fatigue and psychosocial variables on quality of life for patients with motor neuron disease. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 537-45. PMID 23725553 DOI: 10.3109/21678421.2013.799700  0.271
2022 Dubinski A, Gagné M, Peyrard S, Gordon D, Talbot K, Velde CV. Stress granule assembly in vivo is deficient in the CNS of mutant TDP-43 ALS mice. Human Molecular Genetics. PMID 35994036 DOI: 10.1093/hmg/ddac206  0.269
2020 Crow YJ, Marshall H, Rice GI, Seabra L, Jenkinson EM, Baranano K, Battini R, Berger A, Blair E, Blauwblomme T, Bolduc F, Boddaert N, Buckard J, Burnett H, Calvert S, ... ... Talbot K, et al. Leukoencephalopathy with calcifications and cysts: Genetic and phenotypic spectrum. American Journal of Medical Genetics. Part A. PMID 33029936 DOI: 10.1002/ajmg.a.61907  0.268
2013 Larimore J, Ryder PV, Kim KY, Ambrose LA, Chapleau C, Calfa G, Gross C, Bassell GJ, Pozzo-Miller L, Smith Y, Talbot K, Park IH, Faundez V. MeCP2 regulates the synaptic expression of a Dysbindin-BLOC-1 network component in mouse brain and human induced pluripotent stem cell-derived neurons. Plos One. 8: e65069. PMID 23750231 DOI: 10.1371/Journal.Pone.0065069  0.268
2007 Mathew L, Talbot K, Love S, Puvanarajah S, Donaghy M. Treatment of vasculitic peripheral neuropathy: a retrospective analysis of outcome. Qjm : Monthly Journal of the Association of Physicians. 100: 41-51. PMID 17189246 DOI: 10.1093/Qjmed/Hcl125  0.266
2014 Hu MT, Szewczyk-Królikowski K, Tomlinson P, Nithi K, Rolinski M, Murray C, Talbot K, Ebmeier KP, Mackay CE, Ben-Shlomo Y. Predictors of cognitive impairment in an early stage Parkinson's disease cohort. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 351-9. PMID 24395708 DOI: 10.1002/Mds.25748  0.265
2009 Turner MR, Talbot K. Functional vitamin B12 deficiency. Practical Neurology. 9: 37-41. PMID 19151237 DOI: 10.1136/Jnnp.2008.161968  0.265
2012 Sharma R, Hicks S, Berna C, Kennard C, Talbot K, Turner MR. Antisaccade Task As A Biomarker In Mnd Journal of Neurology, Neurosurgery, and Psychiatry. 83. DOI: 10.1136/Jnnp-2011-301993.211  0.262
2020 Kiernan MC, Vucic S, Talbot K, McDermott CJ, Hardiman O, Shefner JM, Al-Chalabi A, Huynh W, Cudkowicz M, Talman P, Van den Berg LH, Dharmadasa T, Wicks P, Reilly C, Turner MR. Improving clinical trial outcomes in amyotrophic lateral sclerosis. Nature Reviews. Neurology. PMID 33340024 DOI: 10.1038/s41582-020-00434-z  0.262
2016 Thompson A, Blackwell V, Marsden R, Lawson C, Brooks J, Nickol AH, Talbot K, East JE, Allan P, Turner MR. A Risk-Stratifying Tool To Enable Late-Stage Peg Insertion In Mnd Journal of Neurology, Neurosurgery, and Psychiatry. 87. DOI: 10.1136/Jnnp-2016-315106.5  0.258
2003 Talbot K, Stradling J, Crosby J, Hilton-Jones D. Reduction in excess daytime sleepiness by modafinil in patients with myotonic dystrophy. Neuromuscular Disorders : Nmd. 13: 357-64. PMID 12798791 DOI: 10.1016/S0960-8966(03)00030-0  0.257
2021 Dafinca R, Barbagallo P, Talbot K. The Role of Mitochondrial Dysfunction and ER Stress in TDP-43 and C9ORF72 ALS. Frontiers in Cellular Neuroscience. 15: 653688. PMID 33867942 DOI: 10.3389/fncel.2021.653688  0.255
2022 De Oliveira HM, Soma A, Baker MR, Turner MR, Talbot K, Williams TL. A survey of current practice in genetic testing in amyotrophic lateral sclerosis in the UK and Republic of Ireland: implications for future planning. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-9. PMID 36458618 DOI: 10.1080/21678421.2022.2150556  0.254
2001 Adams RF, Anslow P, Talbot K. Screwdriver headache: a case of traumatic intracranial hypotension. Clinical Radiology. 56: 676-80. PMID 11467872 DOI: 10.1053/Crad.1999.0461  0.253
2007 Douglas MW, Stephens DP, Burrow JN, Anstey NM, Talbot K, Currie BJ. Murray Valley encephalitis in an adult traveller complicated by long-term flaccid paralysis: case report and review of the literature. Transactions of the Royal Society of Tropical Medicine and Hygiene. 101: 284-8. PMID 17161855 DOI: 10.1016/J.Trstmh.2006.09.005  0.251
2014 Körner S, Menke R, Filippini N, Douaud G, Knight S, Talbot K, Turner M. Deutliche Progression der Schädigung der grauen Substanz bei konstanten Befunden in der weißen Substanz im Krankheitsverlauf der Amyotrophen Lateralsklerose: Eine longitudinale MRT-Studie Klinische Neurophysiologie. 45. DOI: 10.1055/S-0034-1371257  0.251
2013 Gibbons CJ, Thornton EW, Ealing J, Shaw PJ, Talbot K, Tennant A, Young CA. Assessing social isolation in motor neurone disease: a Rasch analysis of the MND Social Withdrawal Scale. Journal of the Neurological Sciences. 334: 112-8. PMID 24011605 DOI: 10.1016/J.Jns.2013.08.002  0.251
2011 Turner MR, Lawrence H, Arnold I, Ansorge O, Talbot K. Catastrophic hyperkalaemia following administration of suxamethonium chloride to a patient with undiagnosed amyotrophic lateral sclerosis. Clinical Medicine (London, England). 11: 292-3. PMID 21902090 DOI: 10.7861/Clinmedicine.11-3-292  0.25
2022 Joilin G, Gray E, Thompson AG, Talbot K, Leigh PN, Newbury SF, Turner MR, Hafezparast M. Profiling non-coding RNA expression in cerebrospinal fluid of amyotrophic lateral sclerosis patients. Annals of Medicine. 54: 3069-3078. PMID 36314539 DOI: 10.1080/07853890.2022.2138530  0.247
2014 Larimore J, Zlatic SA, Gokhale A, Tornieri K, Singleton KS, Mullin AP, Tang J, Talbot K, Faundez V. Mutations in the BLOC-1 subunits dysbindin and muted generate divergent and dosage-dependent phenotypes. The Journal of Biological Chemistry. 289: 14291-300. PMID 24713699 DOI: 10.1074/Jbc.M114.553750  0.244
2012 Gibbons CJ, Cousins R, Pomeroy IM, Ando H, Al-Chalabi A, Chataway J, Constaninescu C, Ealing J, Hawkins C, Morrison K, Palace J, Robertson N, Rog D, Scolding N, Sharrack B, ... ... Talbot K, et al. Work in progress: quality of life (QoL) and neurological disease - trajectories of outcome in neurological conditions (TONiC): a study protocol European Journal of Neurology. 19: 264-264. DOI: 10.1111/J.1468-1331.2012.03888.X  0.244
2018 Thompson AG, Gray E, Mager I, Fischer R, Thézénas ML, Charles PD, Talbot K, Andaloussi SE, Kessler BM, Wood M, Turner MR. UFLC-derived CSF extracellular vesicle origin and proteome. Proteomics. e1800257. PMID 30411858 DOI: 10.1002/Pmic.201800257  0.243
2010 Sharma R, Hicks S, Khan A, Berna C, Kennard C, Talbot K, Turner MR. POD12 Development of a hands-free, eye-tracking version of the Trail Making Test Journal of Neurology, Neurosurgery, and Psychiatry. 81. DOI: 10.1136/Jnnp.2010.226340.112  0.242
2018 Wei W, Keogh MJ, Aryaman J, Golder Z, Kullar PJ, Wilson I, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, Sarraj SA, Morris CM, Ansorge O, et al. Frequency and signature of somatic variants in 1461 human brain exomes. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 30214067 DOI: 10.1038/S41436-018-0274-3  0.239
2021 Nolan M, Barbagallo P, Turner MR, Keogh MJ, Chinnery PF, Talbot K, Ansorge O. Isolated homozygous R217X mutation causes knock-out of functional C-terminal optineurin domains and associated oligodendrogliopathy-dominant ALS-TDP. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 33727253 DOI: 10.1136/jnnp-2020-325803  0.237
2014 Rolinski M, Szewczyk-Krolikowski K, Menke RA, Filippini N, Heise V, Zamboni G, Wilcock G, Talbot K, Hu M, Mackay C. RESTING STATE FMRI DISCERNS EARLY PARKINSON'S FROM CONTROLS Journal of Neurology, Neurosurgery & Psychiatry. 85: e4.118-e4. DOI: 10.1136/Jnnp-2014-309236.204  0.234
2007 Talbot K. Neuromuscular disorders: therapeutic advances. The Lancet. Neurology. 6: 18-9. PMID 17166796 DOI: 10.1016/S1474-4422(06)70667-6  0.233
2021 Chen ZS, Huang X, Talbot K, Chan HYE. A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3. Cell Death & Disease. 12: 136. PMID 33542212 DOI: 10.1038/s41419-021-03444-x  0.231
2011 Talbot K. O16 Mouse models of SMA: implications for the timing and delivery of therapy Neuromuscular Disorders. 21. DOI: 10.1016/S0960-8966(11)70017-7  0.231
2023 Dellar ER, Vendrell I, Talbot K, Kessler BM, Fischer R, Turner MR, Thompson AG. Data-independent acquisition proteomics of cerebrospinal fluid implicates endoplasmic reticulum and inflammatory mechanisms in amyotrophic lateral sclerosis. Journal of Neurochemistry. PMID 38087504 DOI: 10.1111/jnc.16030  0.23
2014 Turner MR, Talbot K. Swallowing and oropharyngeal dysphagia. Clinical Medicine (London, England). 14: 456. PMID 25099863 DOI: 10.7861/Clinmedicine.14-2-196  0.228
2009 Pal S, Malhotra RM, Davenport RJ, Smith C, Talbot K. Progressive unsteadiness in a 68-year-old man with longstanding abdominal pain and altered bowel habit. Practical Neurology. 9: 210-20. PMID 19608770 DOI: 10.1136/Jnnp.2009.182451  0.226
2007 Matthews PM, Talbot K. Magnetic resonance spectroscopic imaging--of prognostic value in amyotrophic lateral sclerosis? Nature Clinical Practice. Neurology. 3: 76-7. PMID 17279079 DOI: 10.1038/Ncpneuro0394  0.226
2022 Gao J, Dharmadasa T, Malaspina A, Shaw PJ, Talbot K, Turner MR, Thompson AG. Creatine kinase and prognosis in amyotrophic lateral sclerosis: a literature review and multi-centre cohort analysis. Journal of Neurology. PMID 35614165 DOI: 10.1007/s00415-022-11195-8  0.219
2013 Bäumer D, East S, Hofer M, Kent L, Waite A, Morris H, Blake D, Talbot K, Ansorge O. C9orf72 hexanucleotide repeat expansion pathology in the Oxford Brain Bank cohort F1000research. 4. DOI: 10.7490/F1000Research.1094877.1  0.218
2009 Talbot K. The sandy (sdy) mouse: a dysbindin-1 mutant relevant to schizophrenia research. Progress in Brain Research. 179: 87-94. PMID 20302821 DOI: 10.1016/S0079-6123(09)17910-4  0.216
2017 Reynolds GL, Talbot K, Sharma SM. Fundus fluorescein angiography in Susac's syndrome. Practical Neurology. PMID 28819045 DOI: 10.1136/Practneurol-2017-001727  0.213
2022 Young CA, Ealing J, McDermott CJ, Williams TL, Al-Chalabi A, Majeed T, Talbot K, Harrower T, Faull C, Malaspina A, Annadale J, Mills RJ, Tennant A. Measuring disability in amyotrophic lateral sclerosis/motor neuron disease: the WHODAS 2.0-36, WHODAS 2.0-32, and WHODAS 2.0-12. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-8. PMID 35876069 DOI: 10.1080/21678421.2022.2102926  0.213
2012 Ioannou C, Talbot K, Ohuma E, Sarris I, Villar J, Conde-Agudelo A, Papageorghiou AT. Systematic review of methodology used in ultrasound studies aimed at creating charts of fetal size. Bjog : An International Journal of Obstetrics and Gynaecology. 119: 1425-39. PMID 22882780 DOI: 10.1111/J.1471-0528.2012.03451.X  0.211
2023 Scaber J, Thompson AG, Farrimond L, Feneberg E, Proudfoot M, Ossher L, Turner MR, Talbot K. Advantages of routine next generation sequencing over standard genetic testing in the ALS clinic. European Journal of Neurology. PMID 37159497 DOI: 10.1111/ene.15855  0.21
2022 Mehta PR, Iacoangeli A, Opie-Martin S, van Vugt JJFA, Al Khleifat A, Bredin A, Ossher L, Andersen PM, Hardiman O, Mehta AR, Fratta P, Talbot K, Al-Chalabi A. The impact of age on genetic testing decisions in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. PMID 36162820 DOI: 10.1093/brain/awac279  0.208
1988 Talbot K, Woolf NJ, Butcher LL. Feline islands of Calleja complex: II. Cholinergic and cholinesterasic features. The Journal of Comparative Neurology. 275: 580-603. PMID 3192758 DOI: 10.1002/Cne.902750407  0.204
2019 Martin SO, Ossher L, Kulka A, Talbot K, Al-Chalabi A. The MND register for England, Wales and Northern Ireland F1000research. 8. DOI: 10.7490/F1000Research.1116346.1  0.203
1975 Butcher LL, Talbot K, Bilezikjian L. Acetylcholinesterase neurons in dopamine-containing regions of the brain. Journal of Neural Transmission. 37: 127-53. PMID 1185160 DOI: 10.1007/Bf01663629  0.203
2017 Farrimond L, Talbot K. Helen Easdale Dimsdale Lancet Neurology. 16: 185. DOI: 10.1016/S1474-4422(16)30384-2  0.203
1988 Talbot K, Woolf NJ, Butcher LL. Feline islands of Calleja complex: I. Cytoarchitectural organization and comparative anatomy. The Journal of Comparative Neurology. 275: 553-79. PMID 3192757 DOI: 10.1002/Cne.902750406  0.202
2022 Husbands E, Talbot K. Pathological laughter and crying in neurological disorders: recognition and treatment. Practical Neurology. PMID 35907635 DOI: 10.1136/pn-2021-003301  0.198
2012 Vanden Hoek AL, Talbot K, Carter IS, Vickars L, Carter CJ, Jackson SC, MacGillivray RT, Pryzdial EL. Coagulation factor X Arg386 specifically affects activation by the intrinsic pathway: a novel patient mutation. Journal of Thrombosis and Haemostasis : Jth. 10: 2613-5. PMID 23039000 DOI: 10.1111/Jth.12021  0.197
2009 Cox MM, Tucker AM, Tang J, Talbot K, Richer DC, Yeh L, Arnold SE. Neurobehavioral abnormalities in the dysbindin-1 mutant, sandy, on a C57BL/6J genetic background. Genes, Brain, and Behavior. 8: 390-7. PMID 19220483 DOI: 10.1111/J.1601-183X.2009.00477.X  0.194
2024 Young CA, Chaouch A, Mcdermott CJ, Al-Chalabi A, Chhetri SK, Talbot K, Malaspina A, Mills R, Tennant A. Improving the measurement properties of the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R): deriving a valid measurement total for the calculation of change. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-10. PMID 38426231 DOI: 10.1080/21678421.2024.2322539  0.194
2023 Kordala AJ, Stoodley J, Ahlskog N, Hanifi M, Garcia Guerra A, Bhomra A, Lim WF, Murray LM, Talbot K, Hammond SM, Wood MJ, Rinaldi C. PRMT inhibitor promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue SMA mice. Embo Molecular Medicine. e17683. PMID 37724723 DOI: 10.15252/emmm.202317683  0.194
1993 Hammond PJ, Talbot K, Chapman R, Ghatei MA, Bloom SR. Vasoactive intestinal peptide, but not pituitary adenylate cyclase-activating peptide, modulates the responsiveness of the gonadotroph to LHRH in man. The Journal of Endocrinology. 137: 529-32. PMID 8371083 DOI: 10.1677/Joe.0.1370529  0.189
1984 Fass B, Talbot K, Butcher LL. Evidence that efferents from the basolateral amygdala innervate the dorsolateral neostriatum in rats. Neuroscience Letters. 44: 71-5. PMID 6717856 DOI: 10.1016/0304-3940(84)90223-4  0.188
2012 Ioannou C, Talbot K, Ohuma E, Sarris I, Villar J, Conde-Agudelo A, Papageorghiou AT. P29.07: Systematic review of methodology used in ultrasound studies aimed at creating charts of fetal size Ultrasound in Obstetrics & Gynecology. 40: 287-287. DOI: 10.1002/Uog.12174  0.187
2024 Goldacre R, Trubshaw M, Morris EJA, Talbot K, Goldacre MJ, Thompson AG, Turner MR. Venous thromboembolism risk in amyotrophic lateral sclerosis: a hospital record-linkage study. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 38548323 DOI: 10.1136/jnnp-2024-333399  0.187
2011 Larimore J, Tornieri K, Ryder PV, Gokhale A, Zlatic SA, Craige B, Lee JD, Talbot K, Pare JF, Smith Y, Faundez V. The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse. Molecular Biology of the Cell. 22: 4854-67. PMID 21998198 DOI: 10.1091/Mbc.E11-07-0592  0.186
2021 Thompson AG, Gray E, Charles PD, Hu MTM, Talbot K, Fischer R, Kessler BM, Turner MR. Network Analysis of the CSF Proteome Characterizes Convergent Pathways of Cellular Dysfunction in ALS. Frontiers in Neuroscience. 15: 642324. PMID 33815045 DOI: 10.3389/fnins.2021.642324  0.186
2013 Multani PK, Hodge R, Estévez MA, Abel T, Kung H, Alter M, Brookshire B, Lucki I, Nall AH, Talbot K, Doyle GA, Lohoff FW. VMAT1 deletion causes neuronal loss in the hippocampus and neurocognitive deficits in spatial discrimination. Neuroscience. 232: 32-44. PMID 23201251 DOI: 10.1016/J.Neuroscience.2012.11.023  0.182
1989 Talbot K. The medical profession has achieved a major change in its smoking behaviour; how might undergraduate medical education achieve a similar change in doctors' drinking habits? Alcohol and Alcoholism (Oxford, Oxfordshire). 24: 339-45. PMID 2789524 DOI: 10.1093/Oxfordjournals.Alcalc.A044920  0.181
2021 Thompson AG, Talbot K, Turner MR. Higher blood high density lipoprotein and apolipoprotein A1 levels are associated with reduced risk of developing amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 34518331 DOI: 10.1136/jnnp-2021-327133  0.181
2022 Gao J, Mewborne QT, Girdhar A, Sheth U, Coyne AN, Punathil R, Kang BG, Dasovich M, Veire A, DeJesus Hernandez M, Liu S, Shi Z, Dafinca R, Fouquerel E, Talbot K, et al. Poly(ADP-ribose) promotes toxicity of arginine-rich dipeptide repeat proteins. Science Translational Medicine. 14: eabq3215. PMID 36103513 DOI: 10.1126/scitranslmed.abq3215  0.168
2020 Joilin G, Gray E, Thompson AG, Bobeva Y, Talbot K, Weishaupt J, Ludolph A, Malaspina A, Leigh PN, Newbury SF, Turner MR, Hafezparast M. Identification of a potential non-coding RNA biomarker signature for amyotrophic lateral sclerosis. Brain Communications. 2: fcaa053. PMID 32613197 DOI: 10.1093/braincomms/fcaa053  0.167
2023 Chen ZS, Ou M, Taylor S, Dafinca R, Peng SI, Talbot K, Chan HYE. Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature Communications. 14: 8420. PMID 38110419 DOI: 10.1038/s41467-023-44215-w  0.162
2015 McDermott CJ, Shaw PJ, Cooper CL, Dixon S, Baird WO, Bradburn MJ, Fitzgerald P, Maguire C, Baxter SK, Williams T, Baudouin SV, Karat D, Talbot K, Stradling J, Maynard N, et al. Safety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): A multicentre, open-label, randomised controlled trial The Lancet Neurology. 14: 883-892. DOI: 10.1016/S1474-4422(15)00152-0  0.161
2016 Chen Y, Bang S, McMullen MF, Kazi H, Talbot K, Ho MX, Carlson G, Arnold SE, Ong WY, Kim SF. Neuronal Activity-Induced Sterol Regulatory Element Binding Protein-1 (SREBP1) is Disrupted in Dysbindin-Null Mice-Potential Link to Cognitive Impairment in Schizophrenia. Molecular Neurobiology. PMID 26873854 DOI: 10.1007/S12035-016-9773-X  0.161
1975 Butcher LL, Talbot K, Bilezikjian L. Localization of acetylcholinesterase within dopamine containing neurons in the zona compacta of the substantia nigra. Proceedings of the Western Pharmacology Society. 18: 256-9. PMID 1178678  0.16
2013 Montaño CM, Irizarry RA, Kaufmann WE, Talbot K, Gur RE, Feinberg AP, Taub MA. Measuring cell-type specific differential methylation in human brain tissue. Genome Biology. 14: R94. PMID 24000956 DOI: 10.1186/Gb-2013-14-8-R94  0.158
2017 Wei W, Keogh MJ, Wilson I, Coxhead J, Ryan S, Rollinson S, Griffin H, Kurzawa-Akanbi M, Santibanez-Koref M, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, et al. Erratum to: Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains. Acta Neuropathologica Communications. 5: 17. PMID 28228164 DOI: 10.1186/s40478-017-0419-7  0.153
2022 Thompson AG, Gray E, Verber N, Bobeva Y, Lombardi V, Shepheard SR, Yildiz O, Feneberg E, Farrimond L, Dharmadasa T, Gray P, Edmond EC, Scaber J, Gagliardi D, Kirby J, ... ... Talbot K, et al. Multicentre appraisal of amyotrophic lateral sclerosis biofluid biomarkers shows primacy of blood neurofilament light chain. Brain Communications. 4: fcac029. PMID 35224491 DOI: 10.1093/braincomms/fcac029  0.153
2006 Talbot K, Cho DS, Ong WY, Benson MA, Han LY, Kazi HA, Kamins J, Hahn CG, Blake DJ, Arnold SE. Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin. Human Molecular Genetics. 15: 3041-54. PMID 16980328 DOI: 10.1093/Hmg/Ddl246  0.152
2023 Thompson AG, Marsden R, Talbot K, Turner MR. Primary care blood tests show lipid profile changes in pre-symptomatic amyotrophic lateral sclerosis. Brain Communications. 5: fcad211. PMID 37577380 DOI: 10.1093/braincomms/fcad211  0.148
2023 Davies JC, Dharmadasa T, Thompson AG, Edmond EC, Yoganathan K, Gao J, Talbot K, Turner MR. Limited value of serum neurofilament light chain in diagnosing amyotrophic lateral sclerosis. Brain Communications. 5: fcad163. PMID 37292457 DOI: 10.1093/braincomms/fcad163  0.145
2010 Wei S, Xu Y, Shi H, Wong SH, Han W, Talbot K, Hong W, Ong WY. EHD1 is a synaptic protein that modulates exocytosis through binding to snapin. Molecular and Cellular Neurosciences. 45: 418-29. PMID 20696250 DOI: 10.1016/J.Mcn.2010.07.014  0.14
1990 Weaver TA, Talbot KJ, Panganiban AT. Spleen necrosis virus gag polyprotein is necessary for particle assembly and release but not for proteolytic processing. Journal of Virology. 64: 2642-52. PMID 2186174  0.137
2012 Bomfim TR, Forny-Germano L, Sathler LB, Brito-Moreira J, Houzel JC, Decker H, Silverman MA, Kazi H, Melo HM, McClean PL, Holscher C, Arnold SE, Talbot K, Klein WL, Munoz DP, et al. An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers. The Journal of Clinical Investigation. 122: 1339-53. PMID 22476196 DOI: 10.1172/Jci57256  0.134
2000 Talbot K, Young RA, Jolly-Tornetta C, Lee VM, Trojanowski JQ, Wolf BA. A frontal variant of Alzheimer's disease exhibits decreased calcium-independent phospholipase A2 activity in the prefrontal cortex. Neurochemistry International. 37: 17-31. PMID 10781842 DOI: 10.1016/S0197-0186(00)00006-1  0.134
1999 Young RA, Talbot K, Gao ZY, Trojanowski JQ, Wolf BA. Phospholipase pathway in Alzheimer's disease brains: decrease in Galphai in dorsolateral prefrontal cortex. Brain Research. Molecular Brain Research. 66: 188-90. PMID 10095092 DOI: 10.1016/S0169-328X(99)00023-6  0.133
1987 MacLeod AR, Talbot K, Smillie LB, Houlker C. Characterization of a cDNA defining a gene family encoding TM30p1, a human fibroblast tropomyosin. Journal of Molecular Biology. 194: 1-10. PMID 3612796 DOI: 10.1016/0022-2836(87)90710-8  0.132
2014 Glen WB, Horowitz B, Carlson GC, Cannon TD, Talbot K, Jentsch JD, Lavin A. Dysbindin-1 loss compromises NMDAR-dependent synaptic plasticity and contextual fear conditioning. Hippocampus. 24: 204-13. PMID 24446171 DOI: 10.1002/Hipo.22215  0.128
2008 Louneva N, Cohen JW, Han LY, Talbot K, Wilson RS, Bennett DA, Trojanowski JQ, Arnold SE. Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease. The American Journal of Pathology. 173: 1488-95. PMID 18818379 DOI: 10.2353/Ajpath.2008.080434  0.127
2014 Talbot K. Brain insulin resistance in Alzheimer's disease and its potential treatment with GLP-1 analogs. Neurodegenerative Disease Management. 4: 31-40. PMID 24640977 DOI: 10.2217/nmt.13.73  0.122
2008 Deacon RM, Cholerton LL, Talbot K, Nair-Roberts RG, Sanderson DJ, Romberg C, Koros E, Bornemann KD, Rawlins JN. Age-dependent and -independent behavioral deficits in Tg2576 mice. Behavioural Brain Research. 189: 126-38. PMID 18261809 DOI: 10.1016/J.Bbr.2007.12.024  0.121
1983 MacLeod AR, Talbot K. A processed gene defining a gene family encoding a human non-muscle tropomyosin. Journal of Molecular Biology. 167: 523-37. PMID 6308263 DOI: 10.1016/S0022-2836(83)80096-5  0.12
2012 Balu DT, Carlson GC, Talbot K, Kazi H, Hill-Smith TE, Easton RM, Birnbaum MJ, Lucki I. Akt1 deficiency in schizophrenia and impairment of hippocampal plasticity and function. Hippocampus. 22: 230-40. PMID 21049487 DOI: 10.1002/Hipo.20887  0.12
2005 Arnold SE, Talbot K, Hahn CG. Neurodevelopment, neuroplasticity, and new genes for schizophrenia. Progress in Brain Research. 147: 319-45. PMID 15581715 DOI: 10.1016/S0079-6123(04)47023-X  0.119
2011 Carlson GC, Talbot K, Halene TB, Gandal MJ, Kazi HA, Schlosser L, Phung QH, Gur RE, Arnold SE, Siegel SJ. Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 108: E962-70. PMID 21969553 DOI: 10.1073/Pnas.1109625108  0.118
1986 MacLeod AR, Houlker C, Reinach FC, Talbot K. The mRNA and RNA-copy pseudogenes encoding TM30nm, a human cytoskeletal tropomyosin. Nucleic Acids Research. 14: 8413-26. PMID 3024106  0.117
2014 González-López A, Albaiceta GM, Talbot K. Newly identified precipitating factors in mechanical ventilation-induced brain damage: implications for treating ICU delirium. Expert Review of Neurotherapeutics. 14: 583-8. PMID 24852225 DOI: 10.1586/14737175.2014.915743  0.115
2003 Uryu K, Giasson BI, Longhi L, Martinez D, Murray I, Conte V, Nakamura M, Saatman K, Talbot K, Horiguchi T, McIntosh T, Lee VM, Trojanowski JQ. Age-dependent synuclein pathology following traumatic brain injury in mice. Experimental Neurology. 184: 214-24. PMID 14637093 DOI: 10.1016/S0014-4886(03)00245-0  0.113
2008 Fairless AH, Dow HC, Toledo MM, Malkus KA, Edelmann M, Li H, Talbot K, Arnold SE, Abel T, Brodkin ES. Low sociability is associated with reduced size of the corpus callosum in the BALB/cJ inbred mouse strain. Brain Research. 1230: 211-7. PMID 18662677 DOI: 10.1016/J.Brainres.2008.07.025  0.107
1985 MacLeod AR, Houlker C, Reinach FC, Smillie LB, Talbot K, Modi G, Walsh FS. A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism. Proceedings of the National Academy of Sciences of the United States of America. 82: 7835-9. PMID 3865200 DOI: 10.1073/Pnas.82.23.7835  0.105
2009 Tang J, LeGros RP, Louneva N, Yeh L, Cohen JW, Hahn CG, Blake DJ, Arnold SE, Talbot K. Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression. Human Molecular Genetics. 18: 3851-63. PMID 19617633 DOI: 10.1093/Hmg/Ddp329  0.103
2004 Talbot K, Eidem WL, Tinsley CL, Benson MA, Thompson EW, Smith RJ, Hahn CG, Siegel SJ, Trojanowski JQ, Gur RE, Blake DJ, Arnold SE. Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia. The Journal of Clinical Investigation. 113: 1353-63. PMID 15124027 DOI: 10.1172/Jci20425  0.103
1983 Talbot K, MacLeod AR. Novel form of non-muscle tropomyosin in human fibroblasts. Journal of Molecular Biology. 164: 159-74. PMID 6842592  0.102
1998 Callahan MA, Handley MA, Lee YH, Talbot KJ, Harper JW, Panganiban AT. Functional interaction of human immunodeficiency virus type 1 Vpu and Gag with a novel member of the tetratricopeptide repeat protein family. Journal of Virology. 72: 5189-97. PMID 9573291  0.101
2013 Talbot K, Meixner SC, Pryzdial EL. Proteolytic modulation of factor Xa-antithrombin complex enhances fibrinolysis in plasma. Biochimica Et Biophysica Acta. 1834: 989-95. PMID 23416531 DOI: 10.1016/j.bbapap.2013.02.007  0.096
2012 Prasad NB, Kowalski J, Tsai HL, Talbot K, Somervell H, Kouniavsky G, Wang Y, Dackiw AP, Westra WH, Clark DP, Libutti SK, Umbricht CB, Zeiger MA. Three-gene molecular diagnostic model for thyroid cancer. Thyroid : Official Journal of the American Thyroid Association. 22: 275-84. PMID 22280184 DOI: 10.1089/thy.2011.0169  0.095
1998 Callahan MA, Handley MA, Lee YH, Talbot KJ, Harper JW, Panganiban AT. Functional interaction of human immunodeficiency virus type 1 Vpu and Gag with a novel member of the tetratricopeptide repeat protein family. Journal of Virology. 72: 8461. PMID 9766974  0.093
2014 Talbot K, Wang HY. The nature, significance, and glucagon-like peptide-1 analog treatment of brain insulin resistance in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S12-25. PMID 24529520 DOI: 10.1016/J.Jalz.2013.12.007  0.093
1994 Geraghty RJ, Talbot KJ, Callahan M, Harper W, Panganiban AT. Cell type-dependence for Vpu function. Journal of Medical Primatology. 23: 146-50. PMID 7966229 DOI: 10.1111/J.1600-0684.1994.Tb00115.X  0.091
2022 Farrimond L, Talbot K. A case of SOD1 deficiency: implications for clinical trials. Brain : a Journal of Neurology. 145: 805-806. PMID 35259258 DOI: 10.1093/brain/awac063  0.089
2011 Prasad N, Kowalski J, Tsai HL, Talbot K, Somervell H, Kouniavsky G, Wang Y, Dackiw A, Westra WH, Clark DP, Libutti SK, Umbricht CB, Zeiger MA. Three-Gene Molecular Diagnostic Model for Thyroid Cancer. Thyroid : Official Journal of the American Thyroid Association. PMID 22150595 DOI: 10.1089/thy.2011-0169  0.087
2007 Squires LN, Talbot KN, Rubakhin SS, Sweedler JV. Serotonin catabolism in the central and enteric nervous systems of rats upon induction of serotonin syndrome. Journal of Neurochemistry. 103: 174-80. PMID 17877637 DOI: 10.1111/J.1471-4159.2007.04739.X  0.085
1992 Bhupalan A, Talbot K, Forbes A, Owen M, Samson D, Murray-Lyon IM. Budd-Chiari syndrome in association with polycystic disease of the liver and kidneys. Journal of the Royal Society of Medicine. 85: 296-7. PMID 1433097  0.085
1986 Workman P, White RA, Talbot K. CB 1954 revisited. I. Disposition kinetics and metabolism. Cancer Chemotherapy and Pharmacology. 16: 1-8. PMID 3940216  0.084
2012 Talbot K, Wang HY, Kazi H, Han LY, Bakshi KP, Stucky A, Fuino RL, Kawaguchi KR, Samoyedny AJ, Wilson RS, Arvanitakis Z, Schneider JA, Wolf BA, Bennett DA, Trojanowski JQ, et al. Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline. The Journal of Clinical Investigation. 122: 1316-38. PMID 22476197 DOI: 10.1172/Jci59903  0.081
2009 Song J, Talbot K, Hewitt J, MacGillivray RT, Pryzdial EL. Differential contributions of Glu96, Asp102 and Asp111 to coagulation factor V/Va metal ion binding and subunit stability. The Biochemical Journal. 422: 257-64. PMID 19522703 DOI: 10.1042/Bj20090405  0.08
2014 Banerjee A, Wang HY, Borgmann-Winter KE, MacDonald ML, Kaprielian H, Stucky A, Kvasic J, Egbujo C, Ray R, Talbot K, Hemby SE, Siegel SJ, Arnold SE, Sleiman P, Chang X, et al. Src kinase as a mediator of convergent molecular abnormalities leading to NMDAR hypoactivity in schizophrenia. Molecular Psychiatry. PMID 25330739 DOI: 10.1038/mp.2014.115  0.079
2010 Soetanto A, Wilson RS, Talbot K, Un A, Schneider JA, Sobiesk M, Kelly J, Leurgans S, Bennett DA, Arnold SE. Association of anxiety and depression with microtubule-associated protein 2- and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans. Archives of General Psychiatry. 67: 448-57. PMID 20439826 DOI: 10.1001/Archgenpsychiatry.2010.48  0.079
2020 Oprişoreanu AM, Smith HL, Arya S, Webster R, Zhong Z, Eaton-Hart C, Wehner D, Cardozo MJ, Becker T, Talbot K, Becker CG. Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation. Cell Reports. 32: 108113. PMID 32846137 DOI: 10.1016/j.celrep.2020.108113  0.077
2011 Talbot K, Louneva N, Cohen JW, Kazi H, Blake DJ, Arnold SE. Synaptic dysbindin-1 reductions in schizophrenia occur in an isoform-specific manner indicating their subsynaptic location. Plos One. 6: e16886. PMID 21390302 DOI: 10.1371/Journal.Pone.0016886  0.077
2015 Kundu J, Michaelson A, Talbot K, Baranov P, Young MJ, Carrier RL. Decellularized retinal matrix: natural platforms for human retinal progenitor cell culture. Acta Biomaterialia. PMID 26621699 DOI: 10.1016/J.Actbio.2015.11.028  0.076
2014 Yap MY, Lo YL, Talbot K, Ong WY. Oxidative stress reduces levels of dysbindin-1A via its PEST domain. Neurochemistry International. 79: 65-9. PMID 25445987 DOI: 10.1016/j.neuint.2014.10.001  0.075
1993 Panganiban AT, Talbot KJ. Efficient insertion from an internal long terminal repeat (LTR)-LTR sequence on a reticuloendotheliosis virus vector is imprecise and cell specific. Journal of Virology. 67: 1564-71. PMID 8382311  0.075
1996 Walsh SM, Saltzman CL, Talbot KD, Aper RL, Brown TD. In vivo validation of in vitro testing of hallucal flexor mechanics. Clinical Biomechanics (Bristol, Avon). 11: 328-332. PMID 11415641 DOI: 10.1016/0268-0033(96)00012-5  0.071
2010 Talbot K, Meixner SC, Pryzdial EL. Enhanced fibrinolysis by proteolysed coagulation factor Xa. Biochimica Et Biophysica Acta. 1804: 723-30. PMID 19931652 DOI: 10.1016/j.bbapap.2009.11.011  0.07
2013 González-López A, López-Alonso I, Aguirre A, Amado-Rodríguez L, Batalla-Solís E, Astudillo A, Tomás-Zapico C, Fueyo A, dos Santos CC, Talbot K, Albaiceta GM. Mechanical ventilation triggers hippocampal apoptosis by vagal and dopaminergic pathways. American Journal of Respiratory and Critical Care Medicine. 188: 693-702. PMID 23962032 DOI: 10.1164/rccm.201304-0691OC  0.069
2010 Talbot K, Song J, Hewitt J, Serrano K, Ho M, Carter CJ, MacGillivray RT, Pryzdial EL. A novel compensating mechanism for homozygous coagulation factor V deficiency suggested by enhanced activated partial thromboplastin time after reconstitution with normal factor V. British Journal of Haematology. 151: 198-200. PMID 20735394 DOI: 10.1111/J.1365-2141.2010.08336.X  0.066
1986 Workman P, Morgan JE, Talbot K, Wright KA, Donaldson J, Twentyman PR. CB 1954 revisited. II. Toxicity and antitumour activity. Cancer Chemotherapy and Pharmacology. 16: 9-14. PMID 3940225 DOI: 10.1007/BF00255279  0.065
1997 Talbot KD, Saltzman CL. Hallucal rotation: a method of measurement and relationship to bunion deformity. Foot & Ankle International. 18: 550-6. PMID 9310765  0.065
1995 Saltzman CL, Nawoczenski DA, Talbot KD. Measurement of the medial longitudinal arch. Archives of Physical Medicine and Rehabilitation. 76: 45-9. PMID 7811174  0.064
2008 Talbot KN, Hartley DE. Combined electro-acoustic stimulation: a beneficial union? Clinical Otolaryngology : Official Journal of Ent-Uk ; Official Journal of Netherlands Society For Oto-Rhino-Laryngology & Cervico-Facial Surgery. 33: 536-45. PMID 19126127 DOI: 10.1111/J.1749-4486.2008.01822.X  0.064
2013 Talbot K. Brain insulin resistance in alzheimer disease and its potential treatment with a mediterranean diet and GLP-1 analogues Psychiatric Times. 30.  0.061
1981 Orwig BA, Dugger HA, Bhuta SI, Talbot KC, Schwarz HJ. The biotransformation of fluproquazone in man and several animal species. Arzneimittel-Forschung. 31: 904-11. PMID 6973984  0.06
2006 Hahn CG, Wang HY, Cho DS, Talbot K, Gur RE, Berrettini WH, Bakshi K, Kamins J, Borgmann-Winter KE, Siegel SJ, Gallop RJ, Arnold SE. Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia. Nature Medicine. 12: 824-8. PMID 16767099 DOI: 10.1038/Nm1418  0.053
2014 Seymour D, Talbot KC, Stutelberg C. Linking compensation to payment incentives. A new challenge for healthcare. Healthcare Executive. 29: 58-60. PMID 25672112  0.052
2011 Matricciani L, Talbot K, Jones S. Safety and efficacy of tinea pedis and onychomycosis treatment in people with diabetes: a systematic review. Journal of Foot and Ankle Research. 4: 26. PMID 22136082 DOI: 10.1186/1757-1146-4-26  0.047
1998 Talbot KD, Saltzman CL. Assessing sesamoid subluxation: how good is the AP radiograph? Foot & Ankle International. 19: 547-54. PMID 9728703  0.047
1982 Talbot KJ, Russell PJ. Nuclear buoyant density determination and the purification and characterization of wild-type neurospora nuclei using percoll density gradients. Plant Physiology. 70: 704-8. PMID 16662561  0.047
2011 Talbot K, Simpson R, Price N, Jackson SR. Heterotopic pregnancy. Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology. 31: 7-12. PMID 21280985 DOI: 10.3109/01443615.2010.522749  0.042
1969 Talbot KJ. Presidential address. Transactions of the Ophthalmological Society of New Zealand. 21: 8-14. PMID 5259099  0.039
1996 Talbot K. Transcending a devastating loss: the life attitude of mothers who have experienced the death of their only child. The Hospice Journal. 11: 67-82. PMID 9256681  0.038
2013 Sheffield WP, Bhakta V, Talbot K, Pryzdial EL, Jenkins C. Quality of frozen transfusable plasma prepared from whole blood donations in Canada: an update. Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society For Haemapheresis. 49: 440-6. PMID 23849252 DOI: 10.1016/j.transci.2013.06.012  0.035
1961 TALBOT KJ. A case of ptosis. Transactions of the Royal Society of Tropical Medicine and Hygiene. 13: 75-8. PMID 13775022  0.034
2014 Talbot KD, Kerns KA. Event- and time-triggered remembering: the impact of attention deficit hyperactivity disorder on prospective memory performance in children. Journal of Experimental Child Psychology. 127: 126-43. PMID 24933706 DOI: 10.1016/j.jecp.2014.02.011  0.033
2012 Jules A, Grijalva CG, Zhu Y, Talbot KH, Williams JV, Dupont WD, Edwards KM, Schaffner W, Shay DK, Griffin MR. Estimating age-specific influenza-related hospitalization rates during the pandemic (H1N1) 2009 in Davidson Co, TN. Influenza and Other Respiratory Viruses. 6: e63-71. PMID 22360812 DOI: 10.1111/J.1750-2659.2012.00343.X  0.032
2013 Liu Y, Cope L, Sun W, Wang Y, Prasad N, Sangenario L, Talbot K, Somervell H, Westra W, Bishop J, Califano J, Zeiger M, Umbricht C. DNA copy number variations characterize benign and malignant thyroid tumors. The Journal of Clinical Endocrinology and Metabolism. 98: E558-66. PMID 23345095 DOI: 10.1210/jc.2012-3113  0.031
1980 Dain JG, Bhuta SI, Coombs RA, Talbot KC, Dugger HA. Metabolism of butalbital, 5-allyl-5-isobutylbarbituric acid, in the dog. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 8: 247-52. PMID 6105059  0.031
2003 Bucci KK, Possidente CJ, Talbot KA. Strategies to improve medication adherence in patients with depression. American Journal of Health-System Pharmacy : Ajhp : Official Journal of the American Society of Health-System Pharmacists. 60: 2601-5. PMID 14735778  0.03
2010 Squires LN, Rubakhin SS, Wadhams AA, Talbot KN, Nakano H, Moroz LL, Sweedler JV. Serotonin and its metabolism in basal deuterostomes: insights from Strongylocentrotus purpuratus and Xenoturbella bocki. The Journal of Experimental Biology. 213: 2647-54. PMID 20639426 DOI: 10.1242/Jeb.042374  0.029
1977 Hazuka BT, Dajani AS, Talbot K, Keen BM. Two outbreaks of Flavobacterium meningosepticum type E in a neonatal intensive care unit. Journal of Clinical Microbiology. 6: 450-55. PMID 925147  0.026
2010 Talbot KK, Neill KS, Rankin LL. Rape-accepting attitudes of university undergraduate students. Journal of Forensic Nursing. 6: 170-9. PMID 21114758 DOI: 10.1111/j.1939-3938.2010.01085.x  0.025
1955 TALBOT KJ. Impressions of ophthalmology in London. Transactions of the Ophthalmological Society of New Zealand. 8: 73-6. PMID 13380983  0.024
2010 Dhadyalla G, McMurran R, Amor-Segan M, Li W, Talbot K, Jones R. Robustness testing against low voltage transients - A novel approach Sae Technical Papers. DOI: 10.4271/2010-01-0195  0.022
1993 Talbot KF, Haude RH. The relation between sign language skill and spatial visualization ability: mental rotation of three-dimensional objects. Perceptual and Motor Skills. 77: 1387-91. PMID 8170794 DOI: 10.2466/pms.1993.77.3f.1387  0.02
2016 Talbot K, Lawrence J. ABN news. Practical Neurology. 16: 252. PMID 27179069 DOI: 10.1136/practneurol-2016-001439  0.02
2016 Talbot K, Lawrence J. ABN news. Practical Neurology. 16: 171. PMID 26980760 DOI: 10.1136/practneurol-2016-001402  0.02
2016 Talbot K, Lawrence J. ABN news. Practical Neurology. 16: 81. PMID 26769763 DOI: 10.1136/practneurol-2015-001359  0.02
1979 Schran HF, Schwarz HJ, Talbot KC, Loeffler LJ. Specific radioimmunoassay of ergot peptide alkaloids in plasma. Clinical Chemistry. 25: 1928-33. PMID 498503  0.019
2012 Glasson D, Meijers G, Schofield A, Talbot K. Cost effective implementation of a shoreline management plan in an environmentally sensitive area: Seasalter to graveney sea defences Innovative Coastal Zone Management: Sustainable Engineering For a Dynamic Coast - 7th International Coastal Management Conference. 597-606. DOI: 10.1680/iczm.57494.597  0.019
2013 Talbot K, Hug B. WHAT MAKES US TICK…TOCK?: USING FRUIT FLIES TO STUDY CIRCADIAN RHYTHMS. Science Teacher (Normal, Ill.). 80: 37-43. PMID 25324580  0.018
2015 Talbot KM. Understanding and healing emotional trauma: conversations with pioneering clinicians and researchers. Journal of Child and Adolescent Mental Health. 27: 157-9. PMID 26357921 DOI: 10.2989/17280583.2015.1086943  0.016
2014 Droniou J, Talbot KS. On a miscible displacement model in porous media flow with measure data Siam Journal On Mathematical Analysis. 46: 3158-3175. DOI: 10.1137/130949294  0.015
1984 Tse FL, Christiano JR, Talbot KC. Relative absorption of tryptophan ethyl ester amide derivatives with various fatty acid chains in the dog. The Journal of Pharmacy and Pharmacology. 36: 633-6. PMID 6149293  0.014
1976 Talbot KW. Eighteen months general practice experience with urban practice nurses. The New Zealand Medical Journal. 83: 407-8. PMID 1067485  0.014
1981 Williams JI, Bhuta SI, Jaffe JM, Migdalof BH, Schwarz HJ, Talbot KC, Brouillard JF, Donatsch P, Hodel C, Lemaire M, Meier J, Schweitzer A. Absorption, distribution, and excretion of fluproquazone in several animal species. Arzneimittel-Forschung. 31: 897-904. PMID 6973983  0.013
1992 el-Chaar GM, Schwenk MH, Bardini J, Caliendo G, Frank C, Profeta LM, Talbot KA, Cohen H. New drugs on the horizon. Clinics in Podiatric Medicine and Surgery. 9: 481-501. PMID 1534032  0.012
2016 Talbot KS. Uniform temporal convergence of numerical schemes for miscible flow through porous media Comptes Rendus Mathematique. 354: 161-165. DOI: 10.1016/j.crma.2015.11.007  0.01
2012 Talbot K, Durrheim K. The Princeton Trilogy revisited: How have racial stereotypes changed in South Africa South African Journal of Psychology. 42: 476-491.  0.01
2012 Ritter J, Schonfeld V, Talbot K. A yearbook of the music of Vienna and Prague, 1796 Haydn and His World. 289-320.  0.01
2010 Talbot K, Quayle M. The perils of being a nice guy: Contextual variation in five young women's constructions of acceptable hegemonic and alternative masculinities Men and Masculinities. 13: 255-278. DOI: 10.1177/1097184X09350408  0.01
1986 Talbot K. ECT: exploring myths, examining attitudes. Journal of Psychosocial Nursing and Mental Health Services. 24: 6-11. PMID 3634013  0.01
1979 Dugger HA, Madrid VO, Talbot KC, Coombs RA, Orwig BA. Biotransformation of mazindol. III. Comparison of metabolism in rat, dog, and man. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 7: 132-7. PMID 38082  0.01
1974 Baker R, Bracken TR, Talbot KW. Letter: Written communications between general practitioners: a simple aid. The New Zealand Medical Journal. 79: 893. PMID 4527884  0.01
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