Bryan J. Traynor, M.D. - Publications

Affiliations: 
National Institute on Aging National Institute of Health, Bethesda, MD, United States 
Area:
Neuromuscular Diseases

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Year Citation  Score
2018 Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, ... ... Traynor BJ, et al. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 97: 1268-1283.e6. PMID 29566793 DOI: 10.1016/j.neuron.2018.02.027  1
2017 Dillman AA, Majounie E, Ding J, Gibbs JR, Hernandez D, Arepalli S, Traynor BJ, Singleton AB, Galter D, Cookson MR. Transcriptomic profiling of the human brain reveals that altered synaptic gene expression is associated with chronological aging. Scientific Reports. 7: 16890. PMID 29203886 DOI: 10.1038/s41598-017-17322-0  0.36
2017 Blauwendraat C, Faghri F, Pihlstrom L, Geiger JT, Elbaz A, Lesage S, Corvol JC, May P, Nicolas A, Abramzon Y, Murphy NA, Gibbs JR, Ryten M, Ferrari R, Bras J, ... ... Traynor BJ, et al. NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases. Neurobiology of Aging. PMID 28602509 DOI: 10.1016/j.neurobiolaging.2017.05.009  0.36
2017 Hibar DP, Adams HH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, ... ... Traynor BJ, et al. Novel genetic loci associated with hippocampal volume. Nature Communications. 8: 13624. PMID 28098162 DOI: 10.1038/ncomms13624  1
2016 Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, ... ... Traynor BJ, et al. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience. PMID 27694991 DOI: 10.1038/nn.4398  1
2016 Fogh I, Lin K, Tiloca C, Rooney J, Gellera C, Diekstra FP, Ratti A, Shatunov A, van Es MA, Proitsi P, Jones A, Sproviero W, Chiò A, McLaughlin RL, Sorarù G, ... ... Traynor BJ, et al. Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis. Jama Neurology. PMID 27244217 DOI: 10.1001/jamaneurol.2016.1114  0.36
2015 Peuralinna T, Myllykangas L, Oinas M, Nalls MA, Keage HA, Isoviita VM, Valori M, Polvikoski T, Paetau A, Sulkava R, Ince PG, Zaccai J, Brayne C, Traynor BJ, Hardy J, et al. Genome-wide association study of neocortical Lewy-related pathology. Annals of Clinical and Translational Neurology. 2: 920-31. PMID 26401513 DOI: 10.1002/acn3.231  0.48
2015 Traynor BJ, Angelini C. [An] enumeration shall be made…. Neurology. 85: 1191-2. PMID 26341871 DOI: 10.1212/WNL.0000000000001998  1
2015 Renton AE, Pliner HA, Provenzano C, Evoli A, Ricciardi R, Nalls MA, Marangi G, Abramzon Y, Arepalli S, Chong S, Hernandez DG, Johnson JO, Bartoccioni E, Scuderi F, Maestri M, ... ... Traynor BJ, et al. A genome-wide association study of myasthenia gravis. Jama Neurology. 72: 396-404. PMID 25643325 DOI: 10.1001/jamaneurol.2014.4103  0.36
2015 Nalls MA, Bras J, Hernandez DG, Keller MF, Majounie E, Renton AE, Saad M, Jansen I, Guerreiro R, Lubbe S, Plagnol V, Gibbs JR, Schulte C, Pankratz N, Sutherland M, ... ... Traynor BJ, et al. NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases. Neurobiology of Aging. 36: 1605.e7-12. PMID 25444595 DOI: 10.1016/j.neurobiolaging.2014.07.028  0.48
2015 Traynor BJ, Renton AE. Exploring the epigenetics of Alzheimer disease. Jama Neurology. 72: 8-9. PMID 25365705 DOI: 10.1001/jamaneurol.2014.3057  1
2015 Solje E, Aaltokallio H, Koivumaa-Honkanen H, Suhonen NM, Moilanen V, Kiviharju A, Traynor B, Tienari PJ, Hartikainen P, Remes AM. The phenotype of the C9ORF72 expansion carriers according to revised criteria for bvFTD Plos One. 10. DOI: 10.1371/journal.pone.0131817  1
2014 Johnson JO, Glynn SM, Gibbs JR, Nalls MA, Sabatelli M, Restagno G, Drory VE, Chiò A, Rogaeva E, Traynor BJ. Mutations in the CHCHD10 gene are a common cause of familial amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 137: e311. PMID 25261972 DOI: 10.1093/brain/awu265  1
2014 Diekstra FP, Van Deerlin VM, van Swieten JC, Al-Chalabi A, Ludolph AC, Weishaupt JH, Hardiman O, Landers JE, Brown RH, van Es MA, Pasterkamp RJ, Koppers M, Andersen PM, Estrada K, Rivadeneira F, ... ... Traynor BJ, et al. C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis. Annals of Neurology. 76: 120-33. PMID 24931836 DOI: 10.1002/ana.24198  0.36
2014 van Doormaal PT, Ticozzi N, Gellera C, Ratti A, Taroni F, Chiò A, Calvo A, Mora G, Restagno G, Traynor BJ, Birve A, Lemmens R, van Es MA, Saris CG, Blauw HM, et al. Analysis of the KIFAP3 gene in amyotrophic lateral sclerosis: a multicenter survival study. Neurobiology of Aging. 35: 2420.e13-4. PMID 24838185 DOI: 10.1016/j.neurobiolaging.2014.04.014  0.36
2014 Pletnikova O, Sloane KL, Renton AE, Traynor BJ, Crain BJ, Reid T, Zu T, Ranum LP, Troncoso JC, Rabins PV, Onyike CU. Hippocampal sclerosis dementia with the C9ORF72 hexanucleotide repeat expansion. Neurobiology of Aging. 35: 2419.e17-21. PMID 24819148 DOI: 10.1016/j.neurobiolaging.2014.04.009  1
2014 Johnson JO, Pioro EP, Boehringer A, Chia R, Feit H, Renton AE, Pliner HA, Abramzon Y, Marangi G, Winborn BJ, Gibbs JR, Nalls MA, Morgan S, Shoai M, Hardy J, ... ... Traynor BJ, et al. Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis. Nature Neuroscience. 17: 664-6. PMID 24686783 DOI: 10.1038/nn.3688  0.48
2014 Pliner HA, Mann DM, Traynor BJ. Searching for Grendel: origin and global spread of the C9ORF72 repeat expansion. Acta Neuropathologica. 127: 391-6. PMID 24496499 DOI: 10.1007/s00401-014-1250-x  1
2014 Cistaro A, Pagani M, Montuschi A, Calvo A, Moglia C, Canosa A, Restagno G, Brunetti M, Traynor BJ, Nobili F, Carrara G, Fania P, Lopiano L, Valentini MC, Chiò A. The metabolic signature of C9ORF72-related ALS: FDG PET comparison with nonmutated patients. European Journal of Nuclear Medicine and Molecular Imaging. 41: 844-52. PMID 24445987 DOI: 10.1007/s00259-013-2667-5  1
2014 Renton AE, Chiò A, Traynor BJ. State of play in amyotrophic lateral sclerosis genetics. Nature Neuroscience. 17: 17-23. PMID 24369373 DOI: 10.1038/nn.3584  1
2014 Fogh I, Ratti A, Gellera C, Lin K, Tiloca C, Moskvina V, Corrado L, Sorarù G, Cereda C, Corti S, Gentilini D, Calini D, Castellotti B, Mazzini L, Querin G, ... ... Traynor BJ, et al. A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis. Human Molecular Genetics. 23: 2220-31. PMID 24256812 DOI: 10.1093/hmg/ddt587  1
2014 Goris A, van Setten J, Diekstra F, Ripke S, Patsopoulos NA, Sawcer SJ, van Es M, Andersen PM, Melki J, Meininger V, Hardiman O, Landers JE, Brown RH, ... ... Traynor BJ, et al. No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis. Human Molecular Genetics. 23: 1916-22. PMID 24234648 DOI: 10.1093/hmg/ddt574  1
2014 Nalls MA, Saad M, Noyce AJ, Keller MF, Schrag A, Bestwick JP, Traynor BJ, Gibbs JR, Hernandez DG, Cookson MR, Morris HR, Williams N, Gasser T, Heutink P, Wood N, et al. Genetic comorbidities in Parkinson's disease. Human Molecular Genetics. 23: 831-41. PMID 24057672 DOI: 10.1093/hmg/ddt465  1
2014 Traynor BJ. A roadmap for genetic testing in ALS. Journal of Neurology, Neurosurgery, and Psychiatry. 85: 476. PMID 23868946 DOI: 10.1136/jnnp-2013-305726  1
2014 Kaivorinne AL, Moilanen V, Kervinen M, Renton AE, Traynor BJ, Majamaa K, Remes AM. Novel TARDBP sequence variant and C9ORF72 repeat expansion in a family with frontotemporal dementia. Alzheimer Disease and Associated Disorders. 28: 190-3. PMID 22892647 DOI: 10.1097/WAD.0b013e318266fae5  1
2013 Wang JC, Spiegel N, Bertelsen S, Le N, McKenna N, Budde JP, Harari O, Kapoor M, Brooks A, Hancock D, Tischfield J, Foroud T, Bierut LJ, Steinbach JH, Edenberg HJ, ... Traynor BJ, et al. Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry. Plos One. 8: e80204. PMID 24303001 DOI: 10.1371/journal.pone.0080204  1
2013 Donnelly CJ, Zhang PW, Pham JT, Haeusler AR, Heusler AR, Mistry NA, Vidensky S, Daley EL, Poth EM, Hoover B, Fines DM, Maragakis N, Tienari PJ, Petrucelli L, Traynor BJ, et al. RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention. Neuron. 80: 415-28. PMID 24139042 DOI: 10.1016/j.neuron.2013.10.015  1
2013 Rytty R, Nikkinen J, Paavola L, Abou Elseoud A, Moilanen V, Visuri A, Tervonen O, Renton AE, Traynor BJ, Kiviniemi V, Remes AM. GroupICA dual regression analysis of resting state networks in a behavioral variant of frontotemporal dementia. Frontiers in Human Neuroscience. 7: 461. PMID 23986673 DOI: 10.3389/fnhum.2013.00461  1
2013 Chiò A, Logroscino G, Traynor BJ, Collins J, Simeone JC, Goldstein LA, White LA. Global epidemiology of amyotrophic lateral sclerosis: a systematic review of the published literature. Neuroepidemiology. 41: 118-30. PMID 23860588 DOI: 10.1159/000351153  1
2013 Landouré G, Zhu PP, Lourenço CM, Johnson JO, Toro C, Bricceno KV, Rinaldi C, Meilleur KG, Sangaré M, Diallo O, Pierson TM, Ishiura H, Tsuji S, Hein N, Fink JK, ... ... Traynor BJ, et al. Hereditary spastic paraplegia type 43 (SPG43) is caused by mutation in C19orf12. Human Mutation. 34: 1357-60. PMID 23857908 DOI: 10.1002/humu.22378  1
2013 Renton AE, Traynor BJ. CRESTing the ALS mountain. Nature Neuroscience. 16: 774-5. PMID 23799466 DOI: 10.1038/nn.3444  1
2013 Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, de Vries B, Terwindt G, Medland SE, Todt U, McArdle WL, Quaye L, Koiranen M, ... ... Traynor BJ, et al. Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nature Genetics. 45: 912-7. PMID 23793025 DOI: 10.1038/ng.2676  1
2013 Mok K, Laaksovirta H, Tienari PJ, Peuralinna T, Myllykangas L, Chiò A, Traynor BJ, Nalls MA, Gurunlian N, Shatunov A, Restagno G, Mora G, Nigel Leigh P, Shaw CE, Morrison KE, et al. Homozygosity analysis in amyotrophic lateral sclerosis. European Journal of Human Genetics : Ejhg. 21: 1429-35. PMID 23612577 DOI: 10.1038/ejhg.2013.59  1
2013 Cannas A, Borghero G, Floris GL, Solla P, Chiò A, Traynor BJ, Calvo A, Restagno G, Majounie E, Costantino E, Piras V, Lavra L, Pani C, Orofino G, Di Stefano F, et al. The p.A382T TARDBP gene mutation in Sardinian patients affected by Parkinson's disease and other degenerative parkinsonisms. Neurogenetics. 14: 161-6. PMID 23546887 DOI: 10.1007/s10048-013-0360-2  1
2013 Kim HJ, Kim NC, Wang YD, Scarborough EA, Moore J, Diaz Z, MacLea KS, Freibaum B, Li S, Molliex A, Kanagaraj AP, Carter R, Boylan KB, Wojtas AM, Rademakers R, ... ... Traynor BJ, et al. Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. Nature. 495: 467-73. PMID 23455423 DOI: 10.1038/nature11922  1
2013 Turner MR, Hardiman O, Benatar M, Brooks BR, Chio A, de Carvalho M, Ince PG, Lin C, Miller RG, Mitsumoto H, Nicholson G, Ravits J, Shaw PJ, Swash M, Talbot K, ... Traynor BJ, et al. Controversies and priorities in amyotrophic lateral sclerosis. The Lancet. Neurology. 12: 310-22. PMID 23415570 DOI: 10.1016/S1474-4422(13)70036-X  1
2013 Kumar A, Gibbs JR, Beilina A, Dillman A, Kumaran R, Trabzuni D, Ryten M, Walker R, Smith C, Traynor BJ, Hardy J, Singleton AB, Cookson MR. Age-associated changes in gene expression in human brain and isolated neurons. Neurobiology of Aging. 34: 1199-209. PMID 23177596 DOI: 10.1016/j.neurobiolaging.2012.10.021  1
2013 Yeh TH, Lai SC, Weng YH, Kuo HC, Wu-Chou YH, Huang CL, Chen RS, Chang HC, Traynor B, Lu CS. Screening for C9orf72 repeat expansions in parkinsonian syndromes. Neurobiology of Aging. 34: 1311.e3-4. PMID 23063644 DOI: 10.1016/j.neurobiolaging.2012.09.002  1
2013 Ahmeti KB, Ajroud-Driss S, Al-Chalabi A, Andersen PM, Armstrong J, Birve A, Blauw HM, Brown RH, Bruijn L, Chen W, Chio A, Comeau MC, Cronin S, Diekstra FP, Soraya Gkazi A, ... ... Traynor BJ, et al. Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. Neurobiology of Aging. 34: 357.e7-19. PMID 22959728 DOI: 10.1016/j.neurobiolaging.2012.07.017  0.36
2013 Chiò A, Mora G, Restagno G, Brunetti M, Ossola I, Barberis M, Ferrucci L, Canosa A, Manera U, Moglia C, Fuda G, Traynor BJ, Calvo A. UNC13A influences survival in Italian amyotrophic lateral sclerosis patients: a population-based study. Neurobiology of Aging. 34: 357.e1-5. PMID 22921269 DOI: 10.1016/j.neurobiolaging.2012.07.016  1
2013 Donnelly CJ, Zhang PW, Pham JT, Haeusler AR, Mistry NA, Vidensky S, Daley EL, Poth EM, Hoover B, Fines DM, Maragakis N, Tienari PJ, Petrucelli L, Traynor BJ, Wang J, et al. RNA Toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention [Neuron, 79, (September 18, 2013), 1222-1231] Neuron. 80: 1102. DOI: 10.1016/j.neuron.2013.10.055  1
2012 Chiò A, Calvo A, Mazzini L, Cantello R, Mora G, Moglia C, Corrado L, D'Alfonso S, Majounie E, Renton A, Pisano F, Ossola I, Brunetti M, Traynor BJ, Restagno G, et al. Extensive genetics of ALS: a population-based study in Italy. Neurology. 79: 1983-9. PMID 23100398 DOI: 10.1212/WNL.0b013e3182735d36  1
2012 Collins M, Riascos D, Kovalik T, An J, Krupa K, Krupa K, Hood BL, Conrads TP, Renton AE, Traynor BJ, Bowser R. The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients. Acta Neuropathologica. 124: 717-32. PMID 22993125 DOI: 10.1007/s00401-012-1045-x  1
2012 Schymick JC, Traynor BJ. Expanding the genetics of amyotrophic lateral sclerosis and frontotemporal dementia. Alzheimer's Research & Therapy. 4: 30. PMID 22835154 DOI: 10.1186/alzrt133  1
2012 O'Dowd S, Curtin D, Waite AJ, Roberts K, Pender N, Reid V, O'Connell M, Williams NM, Morris HR, Traynor BJ, Lynch T. C9ORF72 expansion in amyotrophic lateral sclerosis/frontotemporal dementia also causes parkinsonism. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 1072-4. PMID 22807188 DOI: 10.1002/mds.25022  1
2012 Landouré G, Knight MA, Stanescu H, Taye AA, Shi Y, Diallo O, Johnson JO, Hernandez D, Traynor BJ, Biesecker LG, Elkahloun A, Rinaldi C, Vincent A, Willcox N, et al. A candidate gene for autoimmune myasthenia gravis. Neurology. 79: 342-7. PMID 22744667 DOI: 10.1212/WNL.0b013e318260cbd0  1
2012 Majounie E, Abramzon Y, Renton AE, Keller MF, Traynor BJ, Singleton AB. Large C9orf72 repeat expansions are not a common cause of Parkinson's disease. Neurobiology of Aging. 33: 2527.e1-2. PMID 22721568 DOI: 10.1016/j.neurobiolaging.2012.05.007  1
2012 Sailer A, Scholz SW, Gibbs JR, Tucci A, Johnson JO, Wood NW, Plagnol V, Hummerich H, Ding J, Hernandez D, Hardy J, Federoff HJ, Traynor BJ, Singleton AB, Houlden H. Exome sequencing in an SCA14 family demonstrates its utility in diagnosing heterogeneous diseases. Neurology. 79: 127-31. PMID 22675081 DOI: 10.1212/WNL.0b013e31825f048e  1
2012 Landouré G, Sullivan JM, Johnson JO, Munns CH, Shi Y, Diallo O, Gibbs JR, Gaudet R, Ludlow CL, Fischbeck KH, Traynor BJ, Burnett BG, Sumner CJ. Exome sequencing identifies a novel TRPV4 mutation in a CMT2C family. Neurology. 79: 192-4. PMID 22675077 DOI: 10.1212/WNL.0b013e31825f04b2  1
2012 Abramzon Y, Johnson JO, Scholz SW, Taylor JP, Brunetti M, Calvo A, Mandrioli J, Benatar M, Mora G, Restagno G, Chiò A, Traynor BJ. Valosin-containing protein (VCP) mutations in sporadic amyotrophic lateral sclerosis. Neurobiology of Aging. 33: 2231.e1-2231.e6. PMID 22572540 DOI: 10.1016/j.neurobiolaging.2012.04.005  1
2012 Chiò A, Restagno G, Brunetti M, Ossola I, Calvo A, Canosa A, Moglia C, Floris G, Tacconi P, Marrosu F, Marrosu MG, Murru MR, Majounie E, Renton AE, Abramzon Y, ... ... Traynor BJ, et al. ALS/FTD phenotype in two Sardinian families carrying both C9ORF72 and TARDBP mutations. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 730-3. PMID 22550220 DOI: 10.1136/jnnp-2012-302219  1
2012 Englund E, Gustafson L, Passant U, Majounie E, Renton AE, Traynor BJ, Rohrer JD, Mok K, Hardy J. Familial Lund frontotemporal dementia caused by C9ORF72 hexanucleotide expansion. Neurobiology of Aging. 33: 1850.e13-6. PMID 22483864 DOI: 10.1016/j.neurobiolaging.2012.02.019  0.48
2012 Hernandez DG, Nalls MA, Moore M, Chong S, Dillman A, Trabzuni D, Gibbs JR, Ryten M, Arepalli S, Weale ME, Zonderman AB, Troncoso J, O'Brien R, Walker R, Smith C, ... ... Traynor BJ, et al. Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain. Neurobiology of Disease. 47: 20-8. PMID 22433082 DOI: 10.1016/j.nbd.2012.03.020  1
2012 Sabatelli M, Conforti FL, Zollino M, Mora G, Monsurrò MR, Volanti P, Marinou K, Salvi F, Corbo M, Giannini F, Battistini S, Penco S, Lunetta C, Quattrone A, Gambardella A, ... ... Traynor BJ, et al. C9ORF72 hexanucleotide repeat expansions in the Italian sporadic ALS population. Neurobiology of Aging. 33: 1848.e15-20. PMID 22418734 DOI: 10.1016/j.neurobiolaging.2012.02.011  1
2012 Majounie E, Renton AE, Mok K, Dopper EG, Waite A, Rollinson S, Chiò A, Restagno G, Nicolaou N, Simon-Sanchez J, van Swieten JC, Abramzon Y, Johnson JO, Sendtner M, Pamphlett R, ... ... Traynor BJ, et al. Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study. The Lancet. Neurology. 11: 323-30. PMID 22406228 DOI: 10.1016/S1474-4422(12)70043-1  1
2012 Traynor BJ. Road to the chromosome 9p-linked ALS/FTD locus. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 356-7. PMID 22399792 DOI: 10.1136/jnnp-2012-302429  1
2012 Chiò A, Borghero G, Restagno G, Mora G, Drepper C, Traynor BJ, Sendtner M, Brunetti M, Ossola I, Calvo A, Pugliatti M, Sotgiu MA, Murru MR, Marrosu MG, Marrosu F, et al. Clinical characteristics of patients with familial amyotrophic lateral sclerosis carrying the pathogenic GGGGCC hexanucleotide repeat expansion of C9ORF72. Brain : a Journal of Neurology. 135: 784-93. PMID 22366794 DOI: 10.1093/brain/awr366  1
2012 Cooper-Knock J, Hewitt C, Highley JR, Brockington A, Milano A, Man S, Martindale J, Hartley J, Walsh T, Gelsthorpe C, Baxter L, Forster G, Fox M, Bury J, Mok K, ... ... Traynor BJ, et al. Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72. Brain : a Journal of Neurology. 135: 751-64. PMID 22366792 DOI: 10.1093/brain/awr365  0.48
2012 Floris G, Borghero G, Cannas A, Di Stefano F, Costantino E, Murru MR, Brunetti M, Restagno G, Traynor BJ, Marrosu MG, Chiò A, Marrosu F. Frontotemporal dementia with psychosis, parkinsonism, visuo-spatial dysfunction, upper motor neuron involvement associated to expansion of C9ORF72: a peculiar phenotype? Journal of Neurology. 259: 1749-51. PMID 22323211 DOI: 10.1007/s00415-012-6444-3  1
2012 Panagiotou OA, Ioannidis JPA, Hirschhorn JN, Abecasis GR, Frayling TM, McCarthy MI, Lindgren CM, Beaty TH, Eriksson N, Polychronakos C, Kathirensan S, Plenge RM, Spritz R, Payami H, Martin ER, ... ... Traynor BJ, et al. What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations International Journal of Epidemiology. 41: 273-286. PMID 22253303 DOI: 10.1093/ije/dyr178  1
2012 Majounie E, Abramzon Y, Renton AE, Perry R, Bassett SS, Pletnikova O, Troncoso JC, Hardy J, Singleton AB, Traynor BJ. Repeat expansion in C9ORF72 in Alzheimer's disease. The New England Journal of Medicine. 366: 283-4. PMID 22216764 DOI: 10.1056/NEJMc1113592  1
2012 Mok K, Traynor BJ, Schymick J, Tienari PJ, Laaksovirta H, Peuralinna T, Myllykangas L, Chiò A, Shatunov A, Boeve BF, Boxer AL, DeJesus-Hernandez M, Mackenzie IR, Waite A, Williams N, et al. Chromosome 9 ALS and FTD locus is probably derived from a single founder. Neurobiology of Aging. 33: 209.e3-8. PMID 21925771 DOI: 10.1016/j.neurobiolaging.2011.08.005  1
2012 Majounie E, Traynor BJ, Chiò A, Restagno G, Mandrioli J, Benatar M, Taylor JP, Singleton AB. Mutational analysis of the VCP gene in Parkinson's disease. Neurobiology of Aging. 33: 209.e1-2. PMID 21920633 DOI: 10.1016/j.neurobiolaging.2011.07.011  1
2012 Bogaert E, Goris A, Van Damme P, Geelen V, Lemmens R, van Es MA, van den Berg LH, Sleegers K, Verpoorten N, Timmerman V, De Jonghe P, Van Broeckhoven C, Traynor BJ, Landers JE, Brown RH, et al. Polymorphisms in the GluR2 gene are not associated with amyotrophic lateral sclerosis. Neurobiology of Aging. 33: 418-20. PMID 20409611 DOI: 10.1016/j.neurobiolaging.2010.03.007  1
2011 Beghi E, Pupillo E, Messina P, Giussani G, Chiò A, Zoccolella S, Moglia C, Corbo M, Logroscino G, Al-Chalabi A, Hardiman O, Ludolph A, Mitchell D, Preux PM, Swingler R, ... Traynor BJ, et al. Coffee and amyotrophic lateral sclerosis: A possible preventive role American Journal of Epidemiology. 174: 1002-1008. PMID 21946385 DOI: 10.1093/aje/kwr229  1
2011 Renton AE, Majounie E, Waite A, Simón-Sánchez J, Rollinson S, Gibbs JR, Schymick JC, Laaksovirta H, van Swieten JC, Myllykangas L, Kalimo H, Paetau A, Abramzon Y, Remes AM, Kaganovich A, ... ... Traynor BJ, et al. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron. 72: 257-68. PMID 21944779 DOI: 10.1016/j.neuron.2011.09.010  1
2011 Borghero G, Floris G, Cannas A, Marrosu MG, Murru MR, Costantino E, Parish LD, Pugliatti M, Ticca A, Traynor BJ, Calvo A, Cammarosano S, Moglia C, Cistaro A, Brunetti M, et al. A patient carrying a homozygous p.A382T TARDBP missense mutation shows a syndrome including ALS, extrapyramidal symptoms, and FTD. Neurobiology of Aging. 32: 2327.e1-5. PMID 21803454 DOI: 10.1016/j.neurobiolaging.2011.06.009  1
2011 Peuralinna T, Tanskanen M, Mäkelä M, Polvikoski T, Paetau A, Kalimo H, Sulkava R, Hardy J, Lai SL, Arepalli S, Hernandez D, Traynor BJ, Singleton A, Tienari PJ, Myllykangas L. APOE and AβPP gene variation in cortical and cerebrovascular amyloid-β pathology and Alzheimer's disease: a population-based analysis. Journal of Alzheimer's Disease : Jad. 26: 377-85. PMID 21654062 DOI: 10.3233/JAD-2011-102049  1
2011 Chiò A, Borghero G, Pugliatti M, Ticca A, Calvo A, Moglia C, Mutani R, Brunetti M, Ossola I, Marrosu MG, Murru MR, Floris G, Cannas A, Parish LD, Cossu P, ... ... Traynor BJ, et al. Large proportion of amyotrophic lateral sclerosis cases in Sardinia due to a single founder mutation of the TARDBP gene. Archives of Neurology. 68: 594-8. PMID 21220647 DOI: 10.1001/archneurol.2010.352  1
2011 Hernandez DG, Nalls MA, Gibbs JR, Arepalli S, van der Brug M, Chong S, Moore M, Longo DL, Cookson MR, Traynor BJ, Singleton AB. Distinct DNA methylation changes highly correlated with chronological age in the human brain. Human Molecular Genetics. 20: 1164-72. PMID 21216877 DOI: 10.1093/hmg/ddq561  1
2011 Beghi E, Chiò A, Couratier P, Esteban J, Hardiman O, Logroscino G, Millul A, Mitchell D, Preux PM, Pupillo E, Stevic Z, Swingler R, Traynor BJ, Van den Berg LH, Veldink JH, et al. The epidemiology and treatment of ALS: focus on the heterogeneity of the disease and critical appraisal of therapeutic trials. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 12: 1-10. PMID 20698807 DOI: 10.3109/17482968.2010.502940  1
2011 Chiò A, Calvo A, Moglia C, Ossola I, Brunetti M, Sbaiz L, Lai SL, Abramzon Y, Traynor BJ, Restagno G. A de novo missense mutation of the FUS gene in a "true" sporadic ALS case. Neurobiology of Aging. 32: 553.e23-6. PMID 20598774 DOI: 10.1016/j.neurobiolaging.2010.05.016  1
2011 Lai SL, Abramzon Y, Schymick JC, Stephan DA, Dunckley T, Dillman A, Cookson M, Calvo A, Battistini S, Giannini F, Caponnetto C, Mancardi GL, Spataro R, Monsurro MR, Tedeschi G, ... ... Traynor BJ, et al. FUS mutations in sporadic amyotrophic lateral sclerosis. Neurobiology of Aging. 32: 550.e1-4. PMID 20138404 DOI: 10.1016/j.neurobiolaging.2009.12.020  1
2011 Del Bo R, Corti S, Santoro D, Ghione I, Fenoglio C, Ghezzi S, Ranieri M, Galimberti D, Mancuso M, Siciliano G, Briani C, Murri L, Scarpini E, Schymick JC, Traynor BJ, et al. No major progranulin genetic variability contribution to disease etiopathogenesis in an ALS Italian cohort. Neurobiology of Aging. 32: 1157-8. PMID 19632744 DOI: 10.1016/j.neurobiolaging.2009.06.006  1
2010 Johnson JO, Mandrioli J, Benatar M, Abramzon Y, Van Deerlin VM, Trojanowski JQ, Gibbs JR, Brunetti M, Gronka S, Wuu J, Ding J, McCluskey L, Martinez-Lage M, Falcone D, Hernandez DG, ... ... Traynor BJ, et al. Exome sequencing reveals VCP mutations as a cause of familial ALS. Neuron. 68: 857-64. PMID 21145000 DOI: 10.1016/j.neuron.2010.11.036  1
2010 Traynor BJ, Singleton AB. Nature versus nurture: death of a dogma, and the road ahead. Neuron. 68: 196-200. PMID 20955927 DOI: 10.1016/j.neuron.2010.10.002  1
2010 Singleton AB, Hardy J, Traynor BJ, Houlden H. Towards a complete resolution of the genetic architecture of disease. Trends in Genetics : Tig. 26: 438-42. PMID 20813421 DOI: 10.1016/j.tig.2010.07.004  1
2010 Laaksovirta H, Peuralinna T, Schymick JC, Scholz SW, Lai SL, Myllykangas L, Sulkava R, Jansson L, Hernandez DG, Gibbs JR, Nalls MA, Heckerman D, Tienari PJ, Traynor BJ. Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study. The Lancet. Neurology. 9: 978-85. PMID 20801718 DOI: 10.1016/S1474-4422(10)70184-8  1
2010 Shatunov A, Mok K, Newhouse S, Weale ME, Smith B, Vance C, Johnson L, Veldink JH, van Es MA, van den Berg LH, Robberecht W, Van Damme P, Hardiman O, Farmer AE, Lewis CM, ... ... Traynor BJ, et al. Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study. The Lancet. Neurology. 9: 986-94. PMID 20801717 DOI: 10.1016/S1474-4422(10)70197-6  1
2010 Chiò A, Calvo A, Moglia C, Restagno G, Ossola I, Brunetti M, Montuschi A, Cistaro A, Ticca A, Traynor BJ, Schymick JC, Mutani R, Marrosu MG, Murru MR, Borghero G. Amyotrophic lateral sclerosis-frontotemporal lobar dementia in 3 families with p.Ala382Thr TARDBP mutations. Archives of Neurology. 67: 1002-9. PMID 20697052 DOI: 10.1001/archneurol.2010.173  1
2010 Traynor BJ, Nalls M, Lai SL, Gibbs RJ, Schymick JC, Arepalli S, Hernandez D, van der Brug MP, Johnson JO, Dillman A, Cookson M, Moglia C, Calvo A, Restagno G, Mora G, et al. Kinesin-associated protein 3 (KIFAP3) has no effect on survival in a population-based cohort of ALS patients. Proceedings of the National Academy of Sciences of the United States of America. 107: 12335-8. PMID 20566859 DOI: 10.1073/pnas.0914079107  1
2010 Taes I, Goris A, Lemmens R, van Es MA, van den Berg LH, Chio A, Traynor BJ, Birve A, Andersen P, Slowik A, Tomik B, Brown RH, Shaw CE, Al-Chalabi A, Boonen S, et al. Tau levels do not influence human ALS or motor neuron degeneration in the SOD1G93A mouse. Neurology. 74: 1687-93. PMID 20498436 DOI: 10.1212/WNL.0b013e3181e042f7  1
2010 Gibbs JR, van der Brug MP, Hernandez DG, Traynor BJ, Nalls MA, Lai SL, Arepalli S, Dillman A, Rafferty IP, Troncoso J, Johnson R, Zielke HR, Ferrucci L, Longo DL, Cookson MR, et al. Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. Plos Genetics. 6: e1000952. PMID 20485568 DOI: 10.1371/journal.pgen.1000952  1
2010 Beghi E, Logroscino G, Chiò A, Hardiman O, Millul A, Mitchell D, Swingler R, Traynor BJ. Amyotrophic lateral sclerosis, physical exercise, trauma and sports: results of a population-based pilot case-control study. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 11: 289-92. PMID 20433412 DOI: 10.3109/17482960903384283  1
2010 Logroscino G, Traynor BJ, Hardiman O, Chiò A, Mitchell D, Swingler RJ, Millul A, Benn E, Beghi E. Incidence of amyotrophic lateral sclerosis in Europe. Journal of Neurology, Neurosurgery, and Psychiatry. 81: 385-90. PMID 19710046 DOI: 10.1136/jnnp.2009.183525  1
2009 Simón-Sánchez J, Schulte C, Bras JM, Sharma M, Gibbs JR, Berg D, Paisan-Ruiz C, Lichtner P, Scholz SW, Hernandez DG, Krüger R, Federoff M, Klein C, Goate A, Perlmutter J, ... ... Traynor BJ, et al. Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nature Genetics. 41: 1308-12. PMID 19915575 DOI: 10.1038/ng.487  1
2009 Sha Q, Zhang Z, Schymick JC, Traynor BJ, Zhang S. Genome-wide association reveals three SNPs associated with sporadic amyotrophic lateral sclerosis through a two-locus analysis. Bmc Medical Genetics. 10: 86. PMID 19740415 DOI: 10.1186/1471-2350-10-86  1
2009 Traynor BJ. The era of genomic epidemiology. Neuroepidemiology. 33: 276-9. PMID 19696518 DOI: 10.1159/000235639  1
2009 Scholz SW, Houlden H, Schulte C, Sharma M, Li A, Berg D, Melchers A, Paudel R, Gibbs JR, Simon-Sanchez J, Paisan-Ruiz C, Bras J, Ding J, Chen H, Traynor BJ, et al. SNCA variants are associated with increased risk for multiple system atrophy. Annals of Neurology. 65: 610-4. PMID 19475667 DOI: 10.1002/ana.21685  1
2009 Chiò A, Restagno G, Brunetti M, Ossola I, Calvo A, Mora G, Sabatelli M, Monsurrò MR, Battistini S, Mandrioli J, Salvi F, Spataro R, Schymick J, Traynor BJ, La Bella V, et al. Two Italian kindreds with familial amyotrophic lateral sclerosis due to FUS mutation. Neurobiology of Aging. 30: 1272-5. PMID 19450904 DOI: 10.1016/j.neurobiolaging.2009.05.001  1
2009 Traynor BJ, Singleton AB. What's the FUS! The Lancet. Neurology. 8: 418-9. PMID 19375659 DOI: 10.1016/S1474-4422(09)70088-2  1
2009 Nalls MA, Guerreiro RJ, Simon-Sanchez J, Bras JT, Traynor BJ, Gibbs JR, Launer L, Hardy J, Singleton AB. Extended tracts of homozygosity identify novel candidate genes associated with late-onset Alzheimer's disease. Neurogenetics. 10: 183-90. PMID 19271249 DOI: 10.1007/s10048-009-0182-4  1
2009 Rollinson S, Rizzu P, Sikkink S, Baker M, Halliwell N, Snowden J, Traynor BJ, Ruano D, Cairns N, Rohrer JD, Mead S, Collinge J, Rossor M, Akay E, Guerreiro R, et al. Ubiquitin associated protein 1 is a risk factor for frontotemporal lobar degeneration. Neurobiology of Aging. 30: 656-65. PMID 19217189 DOI: 10.1016/j.neurobiolaging.2009.01.009  1
2009 Chiò A, Schymick JC, Restagno G, Scholz SW, Lombardo F, Lai SL, Mora G, Fung HC, Britton A, Arepalli S, Gibbs JR, Nalls M, Berger S, Kwee LC, Oddone EZ, ... ... Traynor BJ, et al. A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. Human Molecular Genetics. 18: 1524-32. PMID 19193627 DOI: 10.1093/hmg/ddp059  1
2008 Ravits J, Traynor BJ. Current and future directions in genomics of amyotrophic lateral sclerosis. Physical Medicine and Rehabilitation Clinics of North America. 19: 461-77, viii. PMID 18625410 DOI: 10.1016/j.pmr.2008.04.001  1
2008 Landers JE, Shi L, Cho TJ, Glass JD, Shaw CE, Leigh PN, Diekstra F, Polak M, Rodriguez-Leyva I, Niemann S, Traynor BJ, McKenna-Yasek D, Sapp PC, Al-Chalabi A, Wills AM, et al. A common haplotype within the PON1 promoter region is associated with sporadic ALS. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 9: 306-14. PMID 18618303 DOI: 10.1080/17482960802233177  1
2008 Guerreiro RJ, Schymick JC, Crews C, Singleton A, Hardy J, Traynor BJ. TDP-43 is not a common cause of sporadic amyotrophic lateral sclerosis. Plos One. 3: e2450. PMID 18545701 DOI: 10.1371/journal.pone.0002450  1
2008 Jakobsson M, Scholz SW, Scheet P, Gibbs JR, VanLiere JM, Fung HC, Szpiech ZA, Degnan JH, Wang K, Guerreiro R, Bras JM, Schymick JC, Hernandez DG, Traynor BJ, Simon-Sanchez J, et al. Genotype, haplotype and copy-number variation in worldwide human populations. Nature. 451: 998-1003. PMID 18288195 DOI: 10.1038/nature06742  1
2008 Chiò A, Traynor BJ, Lombardo F, Fimognari M, Calvo A, Ghiglione P, Mutani R, Restagno G. Prevalence of SOD1 mutations in the Italian ALS population. Neurology. 70: 533-7. PMID 18268245 DOI: 10.1212/01.wnl.0000299187.90432.3f  1
2008 van Es MA, van Vught PW, Blauw HM, Franke L, Saris CG, Van den Bosch L, de Jong SW, de Jong V, Baas F, van't Slot R, Lemmens R, Schelhaas HJ, Birve A, Sleegers K, Van Broeckhoven C, ... ... Traynor BJ, et al. Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis. Nature Genetics. 40: 29-31. PMID 18084291 DOI: 10.1038/ng.2007.52  1
2008 Logroscino G, Traynor BJ, Hardiman O, Chio' A, Couratier P, Mitchell JD, Swingler RJ, Beghi E. Descriptive epidemiology of amyotrophic lateral sclerosis: new evidence and unsolved issues. Journal of Neurology, Neurosurgery, and Psychiatry. 79: 6-11. PMID 18079297 DOI: 10.1136/jnnp.2006.104828  1
2008 Cronin S, Berger S, Ding J, Schymick JC, Washecka N, Hernandez DG, Greenway MJ, Bradley DG, Traynor BJ, Hardiman O. A genome-wide association study of sporadic ALS in a homogenous Irish population. Human Molecular Genetics. 17: 768-74. PMID 18057069 DOI: 10.1093/hmg/ddm361  1
2008 Chiò A, Traynor BJ, Swingler R, Mitchell D, Hardiman O, Mora G, Beghi E, Logroscino G. Amyotrophic lateral sclerosis and soccer: a different epidemiological approach strengthen the previous findings. Journal of the Neurological Sciences. 269: 187-8; author reply . PMID 17996254 DOI: 10.1016/j.jns.2007.10.005  1
2008 O'Toole O, Traynor BJ, Brennan P, Sheehan C, Frost E, Corr B, Hardiman O. Epidemiology and clinical features of amyotrophic lateral sclerosis in Ireland between 1995 and 2004. Journal of Neurology, Neurosurgery, and Psychiatry. 79: 30-2. PMID 17634215 DOI: 10.1136/jnnp.2007.117788  1
2007 Beghi E, Mennini T, Bendotti C, Bigini P, Logroscino G, Chiò A, Hardiman O, Mitchell D, Swingler R, Traynor BJ, Al-Chalabi A. The heterogeneity of amyotrophic lateral sclerosis: a possible explanation of treatment failure. Current Medicinal Chemistry. 14: 3185-200. PMID 18220753 DOI: 10.2174/092986707782793862  1
2007 Gwinn K, Corriveau RA, Mitsumoto H, Bednarz K, Brown RH, Cudkowicz M, Gordon PH, Hardy J, Kasarskis EJ, Kaufmann P, Miller R, Sorenson E, Tandan R, Traynor BJ, Nash J, et al. Amyotrophic lateral sclerosis: an emerging era of collaborative gene discovery. Plos One. 2: e1254. PMID 18060051 DOI: 10.1371/journal.pone.0001254  1
2007 Schymick JC, Talbot K, Traynor BJ. Genetics of sporadic amyotrophic lateral sclerosis. Human Molecular Genetics. 16: R233-42. PMID 17911166 DOI: 10.1093/hmg/ddm215  1
2007 Traynor BJ, Singleton A. Genome-wide association studies and ALS: are we there yet? The Lancet. Neurology. 6: 841-3. PMID 17884667 DOI: 10.1016/S1474-4422(07)70225-9  1
2007 Bedlack RS, Traynor BJ, Cudkowicz ME. Emerging disease-modifying therapies for the treatment of motor neuron disease/amyotropic lateral sclerosis. Expert Opinion On Emerging Drugs. 12: 229-52. PMID 17604499 DOI: 10.1517/14728214.12.2.229  1
2007 Cronin S, Hardiman O, Traynor BJ. Ethnic variation in the incidence of ALS: a systematic review. Neurology. 68: 1002-7. PMID 17389304 DOI: 10.1212/01.wnl.0000258551.96893.6f  1
2007 Schymick JC, Yang Y, Andersen PM, Vonsattel JP, Greenway M, Momeni P, Elder J, Chiò A, Restagno G, Robberecht W, Dahlberg C, Mukherjee O, Goate A, Graff-Radford N, Caselli RJ, ... ... Traynor BJ, et al. Progranulin mutations and amyotrophic lateral sclerosis or amyotrophic lateral sclerosis-frontotemporal dementia phenotypes. Journal of Neurology, Neurosurgery, and Psychiatry. 78: 754-6. PMID 17371905 DOI: 10.1136/jnnp.2006.109553  1
2007 Schymick JC, Scholz SW, Fung HC, Britton A, Arepalli S, Gibbs JR, Lombardo F, Matarin M, Kasperaviciute D, Hernandez DG, Crews C, Bruijn L, Rothstein J, Mora G, Restagno G, ... ... Traynor BJ, et al. Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data. The Lancet. Neurology. 6: 322-8. PMID 17362836 DOI: 10.1016/S1474-4422(07)70037-6  1
2007 Hardiman O, Cronin S, Traynor BJ. Reply from the authors [8] Neurology. 69: 711-712. DOI: 10.1212/01.wnl.0000285431.01005.67  1
2007 Traynor BJ, Bruijn L, Conwit R, Beal F, O'Neill G, Fagan SC, Cudkowicz ME. Reply from the authors [4] Neurology. 68: 710. DOI: 10.1212/01.wnl.0000258816.02021.b9  1
2006 Momeni P, Schymick J, Jain S, Cookson MR, Cairns NJ, Greggio E, Greenway MJ, Berger S, Pickering-Brown S, Chiò A, Fung HC, Holtzman DM, Huey ED, Wassermann EM, Adamson J, ... ... Traynor BJ, et al. Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD. Bmc Neurology. 6: 44. PMID 17166276 DOI: 10.1186/1471-2377-6-44  1
2006 Beghi E, Logroscino G, Chiò A, Hardiman O, Mitchell D, Swingler R, Traynor BJ. The epidemiology of ALS and the role of population-based registries. Biochimica Et Biophysica Acta. 1762: 1150-7. PMID 17071060 DOI: 10.1016/j.bbadis.2006.09.008  1
2006 Traynor BJ, Bruijn L, Conwit R, Beal F, O'Neill G, Fagan SC, Cudkowicz ME. Neuroprotective agents for clinical trials in ALS: a systematic assessment. Neurology. 67: 20-7. PMID 16832072 DOI: 10.1212/01.wnl.0000223353.34006.54  1
2006 Hardy J, Momeni P, Traynor BJ. Frontal temporal dementia: dissecting the aetiology and pathogenesis. Brain : a Journal of Neurology. 129: 830-1. PMID 16543401 DOI: 10.1093/brain/awl035  1
2004 Greenway MJ, Alexander MD, Ennis S, Traynor BJ, Corr B, Frost E, Green A, Hardiman O. A novel candidate region for ALS on chromosome 14q11.2. Neurology. 63: 1936-8. PMID 15557516  1
2004 Traynor BJ, Zhang H, Shefner JM, Schoenfeld D, Cudkowicz ME. Functional outcome measures as clinical trial endpoints in ALS. Neurology. 63: 1933-5. PMID 15557515  1
2004 Hutchinson M, Galvin R, Sweeney B, Lynch T, Murphy R, Redmond J, Traynor BJ, Hardiman O. Effect of a multidisciplinary clinic on survival in amyotrophic lateral sclerosis [2] (multiple letters) Journal of Neurology, Neurosurgery and Psychiatry. 75: 1208-1209. PMID 15258242 DOI: 10.1136/jnnp.2003.033076  1
2003 Hardiman O, Corr B, Frost E, Gibbons P, Mahon L, Traynor BJ. Access to health services in Ireland for people with Multiple Sclerosis and Motor Neurone Disease. Irish Medical Journal. 96: 200-3. PMID 14518581  1
2003 Traynor BJ, Alexander M, Corr B, Frost E, Hardiman O. Effect of a multidisciplinary amyotrophic lateral sclerosis (ALS) clinic on ALS survival: a population based study, 1996-2000. Journal of Neurology, Neurosurgery, and Psychiatry. 74: 1258-61. PMID 12933930 DOI: 10.1136/jnnp.74.9.1258  1
2003 Traynor BJ, Alexander M, Corr B, Frost E, Hardiman O. An outcome study of riluzole in amyotrophic lateral sclerosis--a population-based study in Ireland, 1996-2000. Journal of Neurology. 250: 473-9. PMID 12700914 DOI: 10.1007/s00415-003-1026-z  1
2002 Hardiman O, Traynor BJ, Corr B, Frost E. Models of care for motor neuron disease: setting standards. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 3: 182-5. PMID 12710506  1
2002 Alexander MD, Traynor BJ, Miller N, Corr B, Frost E, McQuaid S, Brett FM, Green A, Hardiman O. "True" sporadic ALS associated with a novel SOD-1 mutation. Annals of Neurology. 52: 680-3. PMID 12402272 DOI: 10.1002/ana.10369  1
2000 Traynor BJ, Codd MB, Corr B, Forde C, Frost E, Hardiman OM. Clinical features of amyotrophic lateral sclerosis according to the El Escorial and Airlie House diagnostic criteria: A population-based study. Archives of Neurology. 57: 1171-6. PMID 10927797  1
2000 Traynor BJ, Codd MB, Corr B, Forde C, Frost E, Hardiman O. Amyotrophic lateral sclerosis mimic syndromes: a population-based study. Archives of Neurology. 57: 109-13. PMID 10634456  1
1999 Traynor BJ, Codd MB, Corr B, Forde C, Frost E, Hardiman O. Incidence and prevalence of ALS in Ireland, 1995-1997: a population-based study. Neurology. 52: 504-9. PMID 10025778  1
1998 Corr B, Frost E, Traynor BJ, Hardiman O. Service provision for patients with ALS/MND: a cost-effective multidisciplinary approach. Journal of the Neurological Sciences. 160: S141-5. PMID 9851665 DOI: 10.1016/S0022-510X(98)00214-7  1
1998 Groba CB, Walls RM, Sagarin MJ, Nelson LS, Rella J, Hoffman RS, Traynor BJ, Hardiman O, Lowenstein DH, Alldredge BK. Status epilepticus [5] (multiple letters) New England Journal of Medicine. 339: 409-410. PMID 9696663 DOI: 10.1056/NEJM199808063390616  1
Low-probability matches
2019 Bandres-Ciga S, Noyce AJ, Hemani G, Nicolas A, Calvo A, Mora G, Tienari PJ, Stone DJ, Nalls MA, Singleton AB, Chiò A, Traynor BJ. Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis. Annals of Neurology. PMID 30723964 DOI: 10.1002/ana.25431  0.28
2018 Mäkelä M, Kaivola K, Valori M, Paetau A, Polvikoski T, Singleton AB, Traynor BJ, Stone DJ, Peuralinna T, Tienari PJ, Tanskanen M, Myllykangas L. Alzheimer risk loci and associated neuropathology in a population-based study (Vantaa 85+). Neurology. Genetics. 4: e211. PMID 29379882 DOI: 10.1212/NXG.0000000000000211  0.28
2016 Sailer A, Scholz SW, Nalls MA, Schulte C, Federoff M, Price TR, Lees A, Ross OA, Dickson DW, Mok K, Mencacci NE, Schottlaender L, Chelban V, Ling H, O'Sullivan SS, ... ... Traynor BJ, et al. A genome-wide association study in multiple system atrophy. Neurology. PMID 27629089 DOI: 10.1212/WNL.0000000000003221  0.28
2015 Singleton AB, Traynor BJ. Genetics. For complex disease genetics, collaboration drives progress. Science (New York, N.Y.). 347: 1422-3. PMID 25814571 DOI: 10.1126/science.aaa9838  0.28
2014 Keller MF, Ferrucci L, Singleton AB, Tienari PJ, Laaksovirta H, Restagno G, Chiò A, Traynor BJ, Nalls MA. Genome-wide analysis of the heritability of amyotrophic lateral sclerosis. Jama Neurology. 71: 1123-34. PMID 25023141 DOI: 10.1001/jamaneurol.2014.1184  0.28
2019 Kuuluvainen L, Kaivola K, Mönkäre S, Laaksovirta H, Jokela M, Udd B, Valori M, Pasanen P, Paetau A, Traynor BJ, Stone DJ, Schleutker J, Pöyhönen M, Tienari PJ, Myllykangas L. Oligogenic basis of sporadic ALS: The example of p.Ala90Val mutation. Neurology. Genetics. 5: e335. PMID 31086828 DOI: 10.1212/NXG.0000000000000335  0.2
2019 Kaivola K, Kiviharju A, Jansson L, Rantalainen V, Eriksson JG, Strandberg TE, Laaksovirta H, Renton AE, Traynor BJ, Myllykangas L, Tienari PJ. C9orf72 hexanucleotide repeat length in older population: normal variation and effects on cognition. Neurobiology of Aging. PMID 30979436 DOI: 10.1016/j.neurobiolaging.2019.02.026  0.2
2018 Sulkava S, Muggalla P, Sulkava R, Ollila HM, Peuralinna T, Myllykangas L, Kaivola K, Stone DJ, Traynor BJ, Renton AE, Rivera AM, Helisalmi S, Soininen H, Polvikoski T, Hiltunen M, et al. Melatonin receptor type 1A gene linked to Alzheimer's disease in old age. Sleep. PMID 29982836 DOI: 10.1093/sleep/zsy103  0.2
2016 Caress JB, Johnson JO, Abramzon YA, Hawkins GA, Gibbs JR, Sullivan EA, Chahal CS, Traynor BJ. Exome sequencing establishes a gelsolin mutation as the cause of inherited bulbar-onset neuropathy. Muscle & Nerve. PMID 28039894 DOI: 10.1002/mus.25550  0.2
2016 Borghero G, Pugliatti M, Marrosu F, Marrosu MG, Murru MR, Floris G, Cannas A, Occhineri P, Cau TB, Loi D, Ticca A, Traccis S, Manera U, Canosa A, Moglia C, ... ... Traynor BJ, et al. TBK1 is associated with ALS and ALS-FTD in Sardinian patients. Neurobiology of Aging. PMID 27156075 DOI: 10.1016/j.neurobiolaging.2016.03.028  0.2
2015 Chiò A, Mora G, Sabatelli M, Caponnetto C, Lunetta C, Traynor BJ, Johnson JO, Nalls MA, Calvo A, Moglia C, Borghero G, Trojsi F, La Bella V, Volanti P, Simone I, et al. ATNX2 is not a regulatory gene in Italian amyotrophic lateral sclerosis patients with C9ORF72 GGGGCC expansion. Neurobiology of Aging. PMID 26733254 DOI: 10.1016/j.neurobiolaging.2015.11.027  0.2
2015 Borghero G, Pugliatti M, Marrosu F, Marrosu MG, Murru MR, Floris G, Cannas A, Parish LD, Cau TB, Loi D, Ticca A, Traccis S, Manera U, Canosa A, Moglia C, ... ... Traynor BJ, et al. ATXN2 is a modifier of phenotype in ALS patients of Sardinian ancestry. Neurobiology of Aging. 36: 2906.e1-5. PMID 26208502 DOI: 10.1016/j.neurobiolaging.2015.06.013  0.2
2015 Chiò A, Mora G, Sabatelli M, Caponnetto C, Lunetta C, Traynor BJ, Johnson JO, Nalls MA, Calvo A, Moglia C, Borghero G, Monsurrò MR, La Bella V, Volanti P, Simone I, et al. HFE p.H63D polymorphism does not influence ALS phenotype and survival. Neurobiology of Aging. PMID 26174855 DOI: 10.1016/j.neurobiolaging.2015.06.016  0.2
2015 Zukosky K, Meilleur K, Traynor BJ, Dastgir J, Medne L, Devoto M, Collins J, Rooney J, Zou Y, Yang ML, Gibbs JR, Meier M, Stetefeld J, Finkel RS, Schessl J, et al. Association of a Novel ACTA1 Mutation With a Dominant Progressive Scapuloperoneal Myopathy in an Extended Family. Jama Neurology. 72: 689-98. PMID 25938801 DOI: 10.1001/jamaneurol.2015.37  0.2
2015 Chiò A, Mora G, Sabatelli M, Caponnetto C, Traynor BJ, Johnson JO, Nalls MA, Calvo A, Moglia C, Borghero G, Monsurrò MR, La Bella V, Volanti P, Simone I, Salvi F, et al. CHCH10 mutations in an Italian cohort of familial and sporadic amyotrophic lateral sclerosis patients. Neurobiology of Aging. 36: 1767.e3-6. PMID 25726362 DOI: 10.1016/j.neurobiolaging.2015.01.017  0.2
2014 Borghero G, Pugliatti M, Marrosu F, Marrosu MG, Murru MR, Floris G, Cannas A, Parish LD, Occhineri P, Cau TB, Loi D, Ticca A, Traccis S, Manera U, Canosa A, ... ... Traynor BJ, et al. Genetic architecture of ALS in Sardinia. Neurobiology of Aging. 35: 2882.e7-2882.e12. PMID 25123918 DOI: 10.1016/j.neurobiolaging.2014.07.012  0.2
2018 Bradley WG, Andrew AS, Traynor BJ, Chiò A, Butt TH, Stommel EW. Gene-Environment-Time Interactions in Neurodegenerative Diseases: Hypotheses and Research Approaches. Annals of Neurosciences. 25: 261-267. PMID 31000966 DOI: 10.1159/000495321  0.16
2017 Goldstein O, Gana-Weisz M, Nefussy B, Vainer B, Nayshool O, Bar-Shira A, Traynor BJ, Drory VE, Orr-Urtreger A. High frequency of C9orf72 hexanucleotide repeat expansion in amyotrophic lateral sclerosis patients from two founder populations sharing the same risk haplotype. Neurobiology of Aging. PMID 29352617 DOI: 10.1016/j.neurobiolaging.2017.12.015  0.16
2017 Chia R, Chiò A, Traynor BJ. Novel genes associated with amyotrophic lateral sclerosis: diagnostic and clinical implications. The Lancet. Neurology. PMID 29154141 DOI: 10.1016/S1474-4422(17)30401-5  0.16
2017 Murphy NA, Arthur KC, Tienari PJ, Houlden H, Chiò A, Traynor BJ. Age-related penetrance of the C9orf72 repeat expansion. Scientific Reports. 7: 2116. PMID 28522837 DOI: 10.1038/s41598-017-02364-1  0.16
2017 Gendron TF, Chew J, Stankowski JN, Hayes LR, Zhang YJ, Prudencio M, Carlomagno Y, Daughrity LM, Jansen-West K, Perkerson EA, O'Raw A, Cook C, Pregent L, Belzil V, van Blitterswijk M, ... ... Traynor BJ, et al. Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis. Science Translational Medicine. 9. PMID 28356511 DOI: 10.1126/scitranslmed.aai7866  0.16
2017 Calvo A, Moglia C, Canosa A, Cammarosano S, Ilardi A, Bertuzzo D, Traynor BJ, Brunetti M, Barberis M, Mora G, Casale F, Chiò A. Common polymorphisms of CX3CR1 gene modify ALS outcome: A population-based study. Muscle & Nerve. PMID 28342179 DOI: 10.1002/mus.25653  0.16
2017 Stopford MJ, Higginbottom A, Hautbergue GM, Cooper-Knock J, Mulcahy PJ, De Vos KJ, Renton AE, Pliner H, Calvo A, Chio A, Traynor BJ, Azzouz M, Heath PR, Consortium I, Consortium N, et al. C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten. Human Molecular Genetics. PMID 28158451 DOI: 10.1093/hmg/ddx022  0.16
2017 Jeong YH, Ling JP, Lin SZ, Donde AN, Braunstein KE, Majounie E, Traynor BJ, LaClair KD, Lloyd TE, Wong PC. Tdp-43 cryptic exons are highly variable between cell types. Molecular Neurodegeneration. 12: 13. PMID 28153034 DOI: 10.1186/s13024-016-0144-x  0.16
2016 Arthur KC, Doyle C, Chiò A, Traynor BJ. Use of Genetic Testing in Amyotrophic Lateral Sclerosis by Neurologists. Jama Neurology. PMID 27893008 DOI: 10.1001/jamaneurol.2016.4540  0.16
2016 Arthur KC, Calvo A, Price TR, Geiger JT, Chiò A, Traynor BJ. Projected increase in amyotrophic lateral sclerosis from 2015 to 2040. Nature Communications. 7: 12408. PMID 27510634 DOI: 10.1038/ncomms12408  0.16
2016 Goldstein O, Nayshool O, Nefussy B, Traynor BJ, Renton AE, Gana-Weisz M, Drory VE, Orr-Urtreger A. OPTN 691_692insAG is a founder mutation causing recessive ALS and increased risk in heterozygotes. Neurology. PMID 26740678 DOI: 10.1212/WNL.0000000000002334  0.16
2015 Zhang M, Xi Z, Zinman L, Bruni AC, Maletta RG, Curcio SA, Rainero I, Rubino E, Pinessi L, Nacmias B, Sorbi S, Galimberti D, Lang AE, Fox S, Surace EI, ... ... Traynor BJ, et al. Mutation analysis of CHCHD10 in different neurodegenerative diseases. Brain : a Journal of Neurology. PMID 25833818 DOI: 10.1093/brain/awv082  0.16
2015 Rinaldi C, Schmidt T, Situ AJ, Johnson JO, Lee PR, Chen KL, Bott LC, Fadó R, Harmison GH, Parodi S, Grunseich C, Renvoisé B, Biesecker LG, De Michele G, Santorelli FM, ... ... Traynor BJ, et al. Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia. Jama Neurology. 72: 561-70. PMID 25751282 DOI: 10.1001/jamaneurol.2014.4769  0.16
2015 Chiò A, Traynor BJ. Motor neuron disease in 2014. Biomarkers for ALS--in search of the Promised Land. Nature Reviews. Neurology. 11: 72-4. PMID 25534912 DOI: 10.1038/nrneurol.2014.250  0.16
2015 Marangi G, Traynor BJ. Genetic causes of amyotrophic lateral sclerosis: new genetic analysis methodologies entailing new opportunities and challenges. Brain Research. 1607: 75-93. PMID 25316630 DOI: 10.1016/j.brainres.2014.10.009  0.16
2015 Fratta P, Polke JM, Newcombe J, Mizielinska S, Lashley T, Poulter M, Beck J, Preza E, Devoy A, Sidle K, Howard R, Malaspina A, Orrell RW, Clarke J, Lu CH, ... ... Traynor BJ, et al. Screening a UK amyotrophic lateral sclerosis cohort provides evidence of multiple origins of the C9orf72 expansion. Neurobiology of Aging. 36: 546.e1-7. PMID 25179228 DOI: 10.1016/j.neurobiolaging.2014.07.037  0.16
2014 Traynor BJ, Cleveland DW. Special Issue on amyotrophic lateral sclerosis. Experimental Neurology. 262: 73-4. PMID 25158310 DOI: 10.1016/j.expneurol.2014.08.020  0.16
2014 Calvo A, Moglia C, Canosa A, Brunetti M, Barberis M, Traynor BJ, Carrara G, Valentini C, Restagno G, Chiò A. De novo nonsense mutation of the FUS gene in an apparently familial amyotrophic lateral sclerosis case. Neurobiology of Aging. 35: 1513.e7-11. PMID 24439481 DOI: 10.1016/j.neurobiolaging.2013.12.028  0.16
2013 Landqvist Waldö M, Gustafson L, Nilsson K, Traynor BJ, Renton AE, Englund E, Passant U. Frontotemporal dementia with a C9ORF72 expansion in a Swedish family: clinical and neuropathological characteristics. American Journal of Neurodegenerative Disease. 2: 276-86. PMID 24319645  0.16
2013 Kaivorinne AL, Bode MK, Paavola L, Tuominen H, Kallio M, Renton AE, Traynor BJ, Moilanen V, Remes AM. Clinical Characteristics of C9ORF72-Linked Frontotemporal Lobar Degeneration. Dementia and Geriatric Cognitive Disorders Extra. 3: 251-62. PMID 24052799 DOI: 10.1159/000351859  0.16
2017 Heckerman D, Traynor BJ, Picca A, Calvani R, Marzetti E, Hernandez D, Nalls M, Arepali S, Ferrucci L, Landi F. Genetic variants associated with physical performance and anthropometry in old age: a genome-wide association study in the ilSIRENTE cohort. Scientific Reports. 7: 15879. PMID 29158487 DOI: 10.1038/s41598-017-13475-0  0.08
2015 Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivières S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, ... ... Traynor BJ, et al. Common genetic variants influence human subcortical brain structures. Nature. 520: 224-9. PMID 25607358 DOI: 10.1038/nature14101  0.08
2016 Schanz O, Bageac D, Braun L, Traynor B, Lehky TJ, Floeter MK. Cortical hyperexcitability in patients with C9orf72 mutations: relationship to phenotype. Muscle & Nerve. PMID 26799151 DOI: 10.1002/mus.25047  0.04
2019 Ghosh SG, Wang L, Breuss MW, Green JD, Stanley V, Yang X, Ross D, Traynor BJ, Alhashem AM, Azam M, Selim L, Bastaki L, Elbastawisy HI, Temtamy S, Zaki M, et al. Recurrent homozygous damaging mutation in , encoding a protein disulfide isomerase, in four families with microlissencephaly. Journal of Medical Genetics. PMID 31586943 DOI: 10.1136/jmedgenet-2019-106409  0.01
2019 Armon C, Traynor BJ. High BMI is associated with low ALS risk: What does it mean? Neurology. PMID 31243070 DOI: 10.1212/WNL.0000000000007852  0.01
2017 Floeter MK, Traynor BJ, Farren J, Braun LE, Tierney M, Wiggs EA, Wu T. Disease progression in C9orf72 mutation carriers. Neurology. PMID 28615433 DOI: 10.1212/WNL.0000000000004115  0.01
2017 Arthur KC, Rivera AM, Samuels J, Wang Y, Grados M, Goes FS, Maher B, Nestadt G, Traynor BJ. C9orf72 hexanucleotide repeat expansions are not a common cause of obsessive-compulsive disorder. Journal of the Neurological Sciences. 375: 71-72. PMID 28320191 DOI: 10.1016/j.jns.2017.01.040  0.01
2016 Floeter MK, Bageac D, Danielian LE, Braun LE, Traynor BJ, Kwan JY. Longitudinal imaging in C9orf72 mutation carriers: Relationship to phenotype. Neuroimage. Clinical. 12: 1035-1043. PMID 27995069 DOI: 10.1016/j.nicl.2016.10.014  0.01
2016 Traynor BJ, Rademakers R. Dementia Research-A Roadmap for the Next Decade. Jama Neurology. PMID 27942708 DOI: 10.1001/jamaneurol.2016.5004  0.01
2016 Traynor BJ, Abramzon YA. To Dement or Not to Dement, That Is the Question. Jama Neurology. PMID 26903123 DOI: 10.1001/jamaneurol.2015.4984  0.01
2014 Su Z, Zhang Y, Gendron TF, Bauer PO, Chew J, Yang WY, Fostvedt E, Jansen-West K, Belzil VV, Desaro P, Johnston A, Overstreet K, Oh SY, Todd PK, Berry JD, ... ... Traynor BJ, et al. Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS. Neuron. 84: 239. PMID 28898625 DOI: 10.1016/j.neuron.2014.09.019  0.01
2014 Su Z, Zhang Y, Gendron TF, Bauer PO, Chew J, Yang WY, Fostvedt E, Jansen-West K, Belzil VV, Desaro P, Johnston A, Overstreet K, Oh SY, Todd PK, Berry JD, ... ... Traynor BJ, et al. Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS. Neuron. 83: 1043-50. PMID 25132468 DOI: 10.1016/j.neuron.2014.07.041  0.01
2014 Su Z, Zhang Y, Gendron TF, Bauer PO, Chew J, Yang WY, Fostvedt E, Jansen-West K, Belzil VV, Desaro P, Johnston A, Overstreet K, Oh SY, Todd PK, Berry JD, ... ... Traynor BJ, et al. Errata to Discovery of a biomarker and lead small molecules to target r(GGGGCC)-Associated Defects in c9FTD/ALS [Neuron, 83, (2014) 1043-1050] Neuron. 84: 239. DOI: 10.1016/j.neuron.2014.09.019  0.01
2004 Nogueira RG, Traynor BJ, Traynor B. The neurology of varicella-zoster virus: a historical perspective. Archives of Neurology. 61: 1974-7. PMID 15596626 DOI: 10.1001/archneur.61.12.1974  0.01
1998 Traynor BJ, Hardiman O. Status epilepticus. The New England Journal of Medicine. 339: 410. PMID 9696665 DOI: 10.1056/NEJM199808063390617  0.01
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