Xiaocheng Dong, Ph.D. - Publications

Affiliations: 
2002 Ohio State University, Columbus, Columbus, OH 
Area:
Molecular Biology

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Xu L, Zhang X, Xin Y, Ma J, Yang C, Zhang X, Hou G, Dong XC, Sun Z, Xiong X, Cao X. Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway. Cell Death & Disease. 12: 710. PMID 34267188 DOI: 10.1038/s41419-021-03980-6  1
2021 Dong XC, Chowdhury K, Huang M, Kim HG. Signal transduction and molecular regulation in fatty liver disease. Antioxidants & Redox Signaling. PMID 33906425 DOI: 10.1089/ars.2021.0076  0.01
2020 Liu Z, Zhang Y, Graham S, Wang X, Cai D, Huang M, Pique-Regi R, Dong XC, Chen YE, Willer C, Liu W. Causal relationships between NAFLD, T2D and obesity have implications for disease subphenotyping. Journal of Hepatology. PMID 32165250 DOI: 10.1016/J.Jhep.2020.03.006  1
2019 Dong XC. PNPLA3-A Potential Therapeutic Target for Personalized Treatment of Chronic Liver Disease. Frontiers in Medicine. 6: 304. PMID 31921875 DOI: 10.3389/fmed.2019.00304  0.01
2019 Liu Y, Kim HG, Dong E, Dong C, Huang M, Liu Y, Liangpunsakul S, Dong XC. Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 31351129 DOI: 10.1016/j.bbadis.2019.07.011  0.01
2019 Kim HG, Huang M, Xin Y, Zhang Y, Zhang X, Wang G, Liu S, Wan J, Ahmadi AR, Sun Z, Liangpunsakul S, Xiong X, Dong XC. The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice. Journal of Hepatology. PMID 31295533 DOI: 10.1016/j.jhep.2019.06.019  1
2018 Majumder S, Ghoshal K, Datta J, Bai S, Dong X, Quan N, Plass C, Jacob ST. Role of DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma. The Journal of Biological Chemistry. 293: 12948. PMID 30120152 DOI: 10.1074/Jbc.W118.004970  1
2018 Dong X, Ghoshal K, Majumder S, Yadav SP, Jacob ST. Mitochondrial transcription factor A and its downstream targets are up-regulated in a rat hepatoma. The Journal of Biological Chemistry. 293: 12947. PMID 30120151 DOI: 10.1074/Jbc.W118.004969  1
2017 Xiong X, Zhang C, Zhang Y, Fan R, Qian X, Dong XC. Fabp4-Cre-mediated Sirt6 deletion impairs adipose tissue function and metabolic homeostasis in mice. The Journal of Endocrinology. PMID 28385723 DOI: 10.1530/JOE-17-0033  1
2016 Xiong X, Sun X, Wang Q, Qian X, Zhang Y, Pan X, Dong XC. SIRT6 protects against palmitate-induced pancreatic β-cell dysfunction and apoptosis. The Journal of Endocrinology. PMID 27601447 DOI: 10.1530/JOE-16-0317  1
2015 Dong XC. The potential of sestrins as therapeutic targets for diabetes. Expert Opinion On Therapeutic Targets. 19: 1011-5. PMID 25944222 DOI: 10.1517/14728222.2015.1044976  0.01
2013 Riehle C, Wende AR, Sena S, Pires KM, Pereira RO, Zhu Y, Bugger H, Frank D, Bevins J, Chen D, Perry CN, Dong XC, Valdez S, Rech M, Sheng X, et al. Insulin receptor substrate signaling suppresses neonatal autophagy in the heart. The Journal of Clinical Investigation. 123: 5319-33. PMID 24177427 DOI: 10.1172/Jci71171  1
2013 Tao R, Xiong X, Harris RA, White MF, Dong XC. Genetic inactivation of pyruvate dehydrogenase kinases improves hepatic insulin resistance induced diabetes. Plos One. 8: e71997. PMID 23940800 DOI: 10.1371/Journal.Pone.0071997  1
2013 Lin CW, Zhang H, Li M, Xiong X, Chen X, Chen X, Dong XC, Yin XM. Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice. Journal of Hepatology. 58: 993-9. PMID 23339953 DOI: 10.1016/j.jhep.2013.01.011  1
2012 Zhang S, Liu S, Tao R, Wei D, Chen L, Shen W, Yu ZH, Wang L, Jones DR, Dong XC, Zhang ZY. A highly selective and potent PTP-MEG2 inhibitor with therapeutic potential for type 2 diabetes. Journal of the American Chemical Society. 134: 18116-24. PMID 23075115 DOI: 10.1021/ja308212y  1
2011 Sadagurski M, Cheng Z, Rozzo A, Palazzolo I, Kelley GR, Dong X, Krainc D, White MF. IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease. The Journal of Clinical Investigation. 121: 4070-81. PMID 21926467 DOI: 10.1172/Jci46305  1
2011 Zhou L, Xuan Q, Wu B, Xiao J, Dong X, Huang T, Chen H, Zhu Y, Wu K. Retroperitoneal laparoscopic anatrophic nephrolithotomy for large staghorn calculi. International Journal of Urology : Official Journal of the Japanese Urological Association. 18: 126-9. PMID 21198943 DOI: 10.1111/j.1442-2042.2010.02688.x  0.01
2009 Guo S, Copps KD, Dong X, Park S, Cheng Z, Pocai A, Rossetti L, Sajan M, Farese RV, White MF. The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis. Molecular and Cellular Biology. 29: 5070-83. PMID 19596788 DOI: 10.1128/Mcb.00138-09  1
2008 Dong XC, Copps KD, Guo S, Li Y, Kollipara R, DePinho RA, White MF. Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation. Cell Metabolism. 8: 65-76. PMID 18590693 DOI: 10.1016/J.Cmet.2008.06.006  1
2008 Li D, Yin X, Zmuda EJ, Wolford CC, Dong X, White MF, Hai T. The repression of IRS2 gene by ATF3, a stress-inducible gene, contributes to pancreatic beta-cell apoptosis. Diabetes. 57: 635-44. PMID 18057093 DOI: 10.2337/Db07-0717  1
2007 Giraud J, Haas M, Feener EP, Copps KD, Dong X, Dunn SL, White MF. Phosphorylation of Irs1 at SER-522 inhibits insulin signaling. Molecular Endocrinology (Baltimore, Md.). 21: 2294-302. PMID 17579213 DOI: 10.1210/Me.2007-0159  1
2006 Dong X, Park S, Lin X, Copps K, Yi X, White MF. Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth. The Journal of Clinical Investigation. 116: 101-14. PMID 16374520 DOI: 10.1172/Jci25735  1
2006 Park S, Dong X, Fisher TL, Dunn S, Omer AK, Weir G, White MF. Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function. The Journal of Biological Chemistry. 281: 1159-68. PMID 16272563 DOI: 10.1074/Jbc.M508307200  1
2002 Ghoshal K, Datta J, Majumder S, Bai S, Dong X, Parthun M, Jacob ST. Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure. Molecular and Cellular Biology. 22: 8302-19. PMID 12417732 DOI: 10.1128/Mcb.22.23.8302-8319.2002  1
2002 Dong X, Ghoshal K, Majumder S, Yadav SP, Jacob ST. Mitochondrial transcription factor A and its downstream targets are up-regulated in a rat hepatoma. The Journal of Biological Chemistry. 277: 43309-18. PMID 12198131 DOI: 10.1074/Jbc.M206958200  1
2002 Majumder S, Ghoshal K, Datta J, Bai S, Dong X, Quan N, Plass C, Jacob ST. Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma. The Journal of Biological Chemistry. 277: 16048-58. PMID 11844796 DOI: 10.1074/Jbc.M111662200  1
2000 Ghoshal K, Majumder S, Li Z, Dong X, Jacob ST. Suppression of metallothionein gene expression in a rat hepatoma because of promoter-specific DNA methylation. The Journal of Biological Chemistry. 275: 539-47. PMID 10617649 DOI: 10.1074/Jbc.275.1.539  1
1999 Feili-Hariri M, Dong X, Alber SM, Watkins SC, Salter RD, Morel PA. Immunotherapy of NOD mice with bone marrow-derived dendritic cells. Diabetes. 48: 2300-8. PMID 10580417 DOI: 10.2337/Diabetes.48.12.2300  0.01
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