Ann M. Pendergast - Publications

Affiliations: 
Duke University, Durham, NC 
Area:
Neuroscience Biology, General
Website:
https://medschool.duke.edu/about-us/our-faculty/ann-marie-pendergast

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Year Citation  Score
2023 Mayro B, Hoj JP, Cerda-Smith CG, Hutchinson HM, Caminear MW, Thrash HL, Winter PS, Wardell SE, McDonnell DP, Wu C, Wood KC, Pendergast AM. ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1. Proceedings of the National Academy of Sciences of the United States of America. 120: e2210418120. PMID 37040401 DOI: 10.1073/pnas.2210418120  0.343
2022 McKernan CM, Khatri A, Hannigan M, Child J, Chen Q, Mayro B, Snyder D, Nicchitta CV, Pendergast AM. ABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brain. Cell Reports. 40: 111268. PMID 36044842 DOI: 10.1016/j.celrep.2022.111268  0.342
2021 Luttman JH, Colemon A, Mayro B, Pendergast AM. Role of the ABL tyrosine kinases in the epithelial-mesenchymal transition and the metastatic cascade. Cell Communication and Signaling : Ccs. 19: 59. PMID 34022881 DOI: 10.1186/s12964-021-00739-6  0.439
2020 Hoj JP, Mayro B, Pendergast AM. The ABL2 kinase regulates an HSF1-dependent transcriptional program required for lung adenocarcinoma brain metastasis. Proceedings of the National Academy of Sciences of the United States of America. 117: 33486-33495. PMID 33318173 DOI: 10.1073/pnas.2007991117  0.376
2020 Hoj JP, Mayro B, Pendergast AM. A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis. Cell Reports. 29: 3421-3434.e8. PMID 31825826 DOI: 10.1016/J.Celrep.2019.11.018  0.349
2020 Hoj JP, Mayro BJ, Pendergast AM. Abstract B25: An actionable AXL-ABL2-TAZ signaling axis promotes lung adenocarcinoma metastasis to the brain Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-B25  0.433
2019 Khatri A, Kraft BD, Tata PR, Randell SH, Piantadosi CA, Pendergast AM. ABL kinase inhibition promotes lung regeneration through expansion of an SCGB1A1+ SPC+ cell population following bacterial pneumonia. Proceedings of the National Academy of Sciences of the United States of America. 116: 1603-1612. PMID 30655340 DOI: 10.1073/Pnas.1816030116  0.37
2016 Gu JJ, Rouse C, Xu X, Wang J, Onaitis MW, Pendergast AM. Inactivation of ABL kinases suppresses non-small cell lung cancer metastasis. Jci Insight. 1: e89647. PMID 28018973 DOI: 10.1172/Jci.Insight.89647  0.424
2016 Matsumoto Y, La Rose J, Kent OA, Wagner MJ, Narimatsu M, Levy AD, Omar MH, Tong J, Krieger JR, Riggs E, Storozhuk Y, Pasquale J, Ventura M, Yeganeh B, Post M, ... ... Pendergast AM, et al. Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. The Journal of Clinical Investigation. PMID 27797343 DOI: 10.1172/Jci87802  0.39
2016 Wang J, Rouse C, Jasper JS, Pendergast AM. ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling. Science Signaling. 9: ra12. PMID 26838548 DOI: 10.1126/Scisignal.Aad3210  0.385
2016 Khatri A, Wang J, Pendergast AM. Multifunctional Abl kinases in health and disease. Journal of Cell Science. 129: 9-16. PMID 26729027 DOI: 10.1242/Jcs.175521  0.591
2015 Wang J, Pendergast AM. The Emerging Role of ABL Kinases in Solid Tumors. Trends in Cancer. 1: 110-123. PMID 26645050 DOI: 10.1016/J.Trecan.2015.07.004  0.506
2015 Li R, Knight JF, Park M, Pendergast AM. Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility. Plos One. 10: e0124960. PMID 25946048 DOI: 10.1371/Journal.Pone.0124960  0.609
2015 Trampont PC, Zhang L, Giles AJ, Walk SF, Gu JJ, Pendergast AM, Ravichandran KS. ShcA regulates thymocyte proliferation through specific transcription factors and a c-Abl-dependent signaling axis. Molecular and Cellular Biology. 35: 1462-76. PMID 25691660 DOI: 10.1128/Mcb.01084-14  0.49
2014 Sourbier C, Ricketts CJ, Matsumoto S, Crooks DR, Liao PJ, Mannes PZ, Yang Y, Wei MH, Srivastava G, Ghosh S, Chen V, Vocke CD, Merino M, Srinivasan R, Krishna MC, ... ... Pendergast AM, et al. Targeting ABL1-mediated oxidative stress adaptation in fumarate hydratase-deficient cancer. Cancer Cell. 26: 840-50. PMID 25490448 DOI: 10.1016/J.Ccell.2014.10.005  0.329
2013 Chislock EM, Pendergast AM. Abl family kinases regulate endothelial barrier function in vitro and in mice. Plos One. 8: e85231. PMID 24367707 DOI: 10.1371/Journal.Pone.0085231  0.819
2013 Chislock EM, Pendergast AM. Tie2 (to) Abl: Signaling to endothelial cell survival. Cell Cycle (Georgetown, Tex.). 12: 3709-10. PMID 24145226 DOI: 10.4161/Cc.26877  0.84
2013 Greuber EK, Smith-Pearson P, Wang J, Pendergast AM. Role of ABL family kinases in cancer: from leukaemia to solid tumours. Nature Reviews. Cancer. 13: 559-71. PMID 23842646 DOI: 10.1038/Nrc3563  0.571
2013 Chislock EM, Ring C, Pendergast AM. Abl kinases are required for vascular function, Tie2 expression, and angiopoietin-1-mediated survival. Proceedings of the National Academy of Sciences of the United States of America. 110: 12432-7. PMID 23840065 DOI: 10.1073/Pnas.1304188110  0.828
2012 Greuber EK, Pendergast AM. Abl family kinases regulate FcγR-mediated phagocytosis in murine macrophages. Journal of Immunology (Baltimore, Md. : 1950). 189: 5382-92. PMID 23100514 DOI: 10.4049/Jimmunol.1200974  0.591
2012 Gu JJ, Lavau CP, Pugacheva E, Soderblom EJ, Moseley MA, Pendergast AM. Abl family kinases modulate T cell-mediated inflammation and chemokine-induced migration through the adaptor HEF1 and the GTPase Rap1. Science Signaling. 5: ra51. PMID 22810897 DOI: 10.1126/scisignal.2002632  0.448
2011 Li R, Pendergast AM. Arg kinase regulates epithelial cell polarity by targeting β1-integrin and small GTPase pathways. Current Biology : Cb. 21: 1534-42. PMID 21906945 DOI: 10.1016/J.Cub.2011.08.023  0.413
2011 Ring C, Ginsberg MH, Haling J, Pendergast AM. Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin. Proceedings of the National Academy of Sciences of the United States of America. 108: 149-54. PMID 21173240 DOI: 10.1073/Pnas.1012316108  0.38
2010 Smith-Pearson PS, Greuber EK, Yogalingam G, Pendergast AM. Abl kinases are required for invadopodia formation and chemokine-induced invasion. The Journal of Biological Chemistry. 285: 40201-11. PMID 20937825 DOI: 10.1074/Jbc.M110.147330  0.602
2009 Gu JJ, Ryu JR, Pendergast AM. Abl tyrosine kinases in T-cell signaling. Immunological Reviews. 228: 170-83. PMID 19290927 DOI: 10.1111/J.1600-065X.2008.00751.X  0.534
2009 Ryu JR, Echarri A, Li R, Pendergast AM. Regulation of cell-cell adhesion by Abi/Diaphanous complexes. Molecular and Cellular Biology. 29: 1735-48. PMID 19158278 DOI: 10.1128/Mcb.01483-08  0.41
2008 Yogalingam G, Pendergast AM. Abl kinases regulate autophagy by promoting the trafficking and function of lysosomal components. The Journal of Biological Chemistry. 283: 35941-53. PMID 18945674 DOI: 10.1074/Jbc.M804543200  0.567
2008 Augustine CK, Yoshimoto Y, Gupta M, Zipfel PA, Selim MA, Febbo P, Pendergast AM, Peters WP, Tyler DS. Targeting N-cadherin enhances antitumor activity of cytotoxic therapies in melanoma treatment. Cancer Research. 68: 3777-84. PMID 18483261 DOI: 10.1158/0008-5472.Can-07-5949  0.314
2008 Zandy NL, Pendergast AM. Abl tyrosine kinases modulate cadherin-dependent adhesion upstream and downstream of Rho family GTPases. Cell Cycle (Georgetown, Tex.). 7: 444-8. PMID 18235247 DOI: 10.4161/Cc.7.4.5452  0.816
2008 Jung JH, Pendergast AM, Zipfel PA, Traugh JA. Phosphorylation of c-Abl by protein kinase Pak2 regulates differential binding of ABI2 and CRK. Biochemistry. 47: 1094-104. PMID 18161990 DOI: 10.1021/Bi701533J  0.749
2007 Gu JJ, Zhang N, He YW, Koleske AJ, Pendergast AM. Defective T cell development and function in the absence of Abelson kinases. Journal of Immunology (Baltimore, Md. : 1950). 179: 7334-43. PMID 18025176 DOI: 10.4049/Jimmunol.179.11.7334  0.429
2007 Zandy NL, Playford M, Pendergast AM. Abl tyrosine kinases regulate cell-cell adhesion through Rho GTPases. Proceedings of the National Academy of Sciences of the United States of America. 104: 17686-91. PMID 17965237 DOI: 10.1073/Pnas.0703077104  0.814
2007 Tanos BE, Pendergast AM. Abi-1 forms an epidermal growth factor-inducible complex with Cbl: role in receptor endocytosis. Cellular Signalling. 19: 1602-9. PMID 17395426 DOI: 10.1016/J.Cellsig.2007.02.008  0.826
2006 Tanos B, Pendergast AM. Abl tyrosine kinase regulates endocytosis of the epidermal growth factor receptor. The Journal of Biological Chemistry. 281: 32714-23. PMID 16943190 DOI: 10.1074/Jbc.M603126200  0.809
2006 Burton EA, Pendergast AM, Aballay A. The Caenorhabditis elegans ABL-1 tyrosine kinase is required for Shigella flexneri pathogenesis. Applied and Environmental Microbiology. 72: 5043-51. PMID 16820504 DOI: 10.1128/Aem.00558-06  0.374
2006 Zipfel PA, Bunnell SC, Witherow DS, Gu JJ, Chislock EM, Ring C, Pendergast AM. Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling. Current Biology : Cb. 16: 35-46. PMID 16401422 DOI: 10.1016/J.Cub.2005.12.024  0.764
2005 Burton EA, Oliver TN, Pendergast AM. Abl kinases regulate actin comet tail elongation via an N-WASP-dependent pathway. Molecular and Cellular Biology. 25: 8834-43. PMID 16199863 DOI: 10.1128/Mcb.25.20.8834-8843.2005  0.561
2005 Pendergast AM. Stress and death: breaking up the c-Abl/14-3-3 complex in apoptosis. Nature Cell Biology. 7: 213-4. PMID 15738971 DOI: 10.1038/Ncb0305-213  0.439
2004 Grove M, Demyanenko G, Echarri A, Zipfel PA, Quiroz ME, Rodriguiz RM, Playford M, Martensen SA, Robinson MR, Wetsel WC, Maness PF, Pendergast AM. ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. Molecular and Cellular Biology. 24: 10905-22. PMID 15572692 DOI: 10.1128/Mcb.24.24.10905-10922.2004  0.434
2004 Zipfel PA, Zhang W, Quiroz M, Pendergast AM. Requirement for Abl kinases in T cell receptor signaling. Current Biology : Cb. 14: 1222-31. PMID 15268851 DOI: 10.1016/J.Cub.2004.07.021  0.525
2004 Plattner R, Koleske AJ, Kazlauskas A, Pendergast AM. Bidirectional signaling links the Abelson kinases to the platelet-derived growth factor receptor. Molecular and Cellular Biology. 24: 2573-83. PMID 14993293 DOI: 10.1128/Mcb.24.6.2573-2583.2004  0.742
2004 Advani AS, Dressman HK, Quiroz M, Taylor GA, Pendergast AM. Elevated expression of a subset of interferon inducible genes in primary bone marrow cells expressing p185 Bcr-Abl versus p210 Bcr-Abl by DNA microarray analysis. Leukemia Research. 28: 285-94. PMID 14687624 DOI: 10.1016/S0145-2126(03)00264-9  0.301
2003 Burton EA, Plattner R, Pendergast AM. Abl tyrosine kinases are required for infection by Shigella flexneri. The Embo Journal. 22: 5471-9. PMID 14532119 DOI: 10.1093/Emboj/Cdg512  0.739
2003 Plattner R, Pendergast AM. Activation and signaling of the Abl tyrosine kinase: bidirectional link with phosphoinositide signaling. Cell Cycle (Georgetown, Tex.). 2: 273-4. PMID 12851468 DOI: 10.4161/Cc.2.4.409  0.696
2003 Finn AJ, Feng G, Pendergast AM. Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction. Nature Neuroscience. 6: 717-23. PMID 12796783 DOI: 10.1038/Nn1071  0.842
2003 Plattner R, Irvin BJ, Guo S, Blackburn K, Kazlauskas A, Abraham RT, York JD, Pendergast AM. A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1. Nature Cell Biology. 5: 309-19. PMID 12652307 DOI: 10.1038/Ncb949  0.719
2002 Pendergast AM. The Abl family kinases: mechanisms of regulation and signaling. Advances in Cancer Research. 85: 51-100. PMID 12374288 DOI: 10.1016/S0065-230X(02)85003-5  0.512
2002 Advani AS, Pendergast AM. Bcr-Abl variants: biological and clinical aspects. Leukemia Research. 26: 713-20. PMID 12191565 DOI: 10.1016/S0145-2126(01)00197-7  0.406
2001 Echarri A, Pendergast AM. Activated c-Abl is degraded by the ubiquitin-dependent proteasome pathway. Current Biology : Cb. 11: 1759-65. PMID 11719217 DOI: 10.1016/S0960-9822(01)00538-3  0.534
2001 Stradal T, Courtney KD, Rottner K, Hahne P, Small JV, Pendergast AM. The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia. Current Biology : Cb. 11: 891-5. PMID 11516653 DOI: 10.1016/S0960-9822(01)00239-1  0.705
2000 Roig J, Tuazon PT, Zipfel PA, Pendergast AM, Traugh JA. Functional interaction between c-Abl and the p21-activated protein kinase gamma-PAK. Proceedings of the National Academy of Sciences of the United States of America. 97: 14346-51. PMID 11121037 DOI: 10.1073/Pnas.97.26.14346  0.716
2000 Zipfel PA, Grove M, Blackburn K, Fujimoto M, Tedder TF, Pendergast AM. The c-Abl tyrosine kinase is regulated downstream of the B cell antigen receptor and interacts with CD19. Journal of Immunology (Baltimore, Md. : 1950). 165: 6872-9. PMID 11120811 DOI: 10.4049/Jimmunol.165.12.6872  0.497
2000 Courtney KD, Grove M, Vandongen H, Vandongen A, LaMantia AS, Pendergast AM. Localization and phosphorylation of Abl-interactor proteins, Abi-1 and Abi-2, in the developing nervous system. Molecular and Cellular Neurosciences. 16: 244-57. PMID 10995551 DOI: 10.1006/Mcne.2000.0865  0.721
2000 Quackenbush RC, Reuther GW, Miller JP, Courtney KD, Pear WS, Pendergast AM. Analysis of the biologic properties of p230 Bcr-Abl reveals unique and overlapping properties with the oncogenic p185 and p210 Bcr-Abl tyrosine kinases. Blood. 95: 2913-21. PMID 10779439  0.617
2000 Quackenbush RC, Reuther GW, Miller JP, Courtney KD, Pear WS, Pendergast AM. Analysis of the biologic properties of p230 Bcr-Abl reveals unique and overlapping properties with the oncogenic p185 and p210 Bcr-Abl tyrosine kinases Blood. 95: 2913-2921. DOI: 10.1182/Blood.V95.9.2913.009K32_2913_2921  0.764
1999 Plattner R, Kadlec L, DeMali KA, Kazlauskas A, Pendergast AM. c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF. Genes & Development. 13: 2400-11. PMID 10500097 DOI: 10.1101/Gad.13.18.2400  0.827
1999 Salgia R, Quackenbush E, Lin J, Souchkova N, Sattler M, Ewaniuk DS, Klucher KM, Daley GQ, Kraeft SK, Sackstein R, Alyea EP, Andrian UHv, Chen LB, Gutierrez-Ramos J, Pendergast A, et al. The BCR/ABL Oncogene Alters the Chemotactic Response to Stromal-Derived Factor-1 Blood. 94: 4233-4246. DOI: 10.1182/Blood.V94.12.4233.424K37_4233_4246  0.385
1998 Pear WS, Miller JP, Xu L, Pui JC, Soffer B, Quackenbush RC, Pendergast AM, Bronson R, Aster JC, Scott ML, Baltimore D. Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow. Blood. 92: 3780-92. PMID 9808572 DOI: 10.1182/Blood.V92.10.3780.422K15_3780_3792  0.463
1998 Dai Z, Quackenbush RC, Courtney KD, Grove M, Cortez D, Reuther GW, Pendergast AM. Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway. Genes & Development. 12: 1415-24. PMID 9585502 DOI: 10.1101/Gad.12.10.1415  0.842
1998 Lamontagne KR, Flint AJ, Franza BR, Pendergast AM, Tonks NK. Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo Molecular and Cellular Biology. 18: 2965-2975. PMID 9566916 DOI: 10.1128/Mcb.18.5.2965  0.53
1998 Reuther JY, Reuther GW, Cortez D, Pendergast AM, Baldwin AS. A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation. Genes & Development. 12: 968-81. PMID 9531535 DOI: 10.1101/Gad.12.7.968  0.776
1997 Cortez D, Reuther G, Pendergast AM. The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells. Oncogene. 15: 2333-42. PMID 9393877 DOI: 10.1038/Sj.Onc.1201400  0.822
1997 Kadlec L, Pendergast AM. The amphiphysin-like protein 1 (ALP1) interacts functionally with the cABL tyrosine kinase and may play a role in cytoskeletal regulation. Proceedings of the National Academy of Sciences of the United States of America. 94: 12390-5. PMID 9356459 DOI: 10.1073/Pnas.94.23.12390  0.818
1996 Cortez D, Stoica G, Pierce JH, Pendergast AM. The BCR-ABL tyrosine kinase inhibits apoptosis by activating a Ras-dependent signaling pathway. Oncogene. 13: 2589-94. PMID 9000132  0.328
1996 Lee DM, Patel DD, Pendergast AM, Haynes BF. Functional association of CD7 with phosphatidylinositol 3-kinase: interaction via a YEDM motif. International Immunology. 8: 1195-203. PMID 8918688 DOI: 10.1093/Intimm/8.8.1195  0.452
1996 Reuther GW, Pendergast AM. The roles of 14-3-3 proteins in signal transduction. Vitamins and Hormones. 52: 149-75. PMID 8909160 DOI: 10.1016/S0083-6729(08)60410-0  0.693
1996 Pendergast AM. Nuclear tyrosine kinases: from Abl to WEE1. Current Opinion in Cell Biology. 8: 174-81. PMID 8791414 DOI: 10.1016/S0955-0674(96)80063-9  0.607
1995 Xie Y, Pendergast AM, Hung MC. Dominant-negative mutants of Grb2 induced reversal of the transformed phenotypes caused by the point mutation-activated rat HER-2/Neu. The Journal of Biological Chemistry. 270: 30717-24. PMID 8530511 DOI: 10.1074/Jbc.270.51.30717  0.446
1995 Dai Z, Pendergast AM. Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity. Genes & Development. 9: 2569-82. PMID 7590236 DOI: 10.1101/Gad.9.21.2569  0.481
1995 Cortez D, Kadlec L, Pendergast AM. Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis. Molecular and Cellular Biology. 15: 5531-41. PMID 7565705 DOI: 10.1128/Mcb.15.10.5531  0.819
1995 Gishizky ML, Cortez D, Pendergast AM. Mutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation. Proceedings of the National Academy of Sciences of the United States of America. 92: 10889-93. PMID 7479904 DOI: 10.1073/Pnas.92.24.10889  0.733
1995 Dai Z, Pendergast AM. Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity Genes and Development. 9.  0.379
1994 Reuther GW, Fu H, Cripe LD, Collier RJ, Pendergast AM. Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family. Science (New York, N.Y.). 266: 129-33. PMID 7939633 DOI: 10.1126/Science.7939633  0.84
1993 Pendergast AM, Gishizky ML, Havlik MH, Witte ON. SH1 domain autophosphorylation of P210 BCR/ABL is required for transformation but not growth factor independence. Molecular and Cellular Biology. 13: 1728-36. PMID 8441409 DOI: 10.1128/Mcb.13.3.1728  0.675
1993 Pendergast AM, Quilliam LA, Cripe LD, Bassing CH, Dai Z, Li N, Batzer A, Rabun KM, Der CJ, Schlessinger J. BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein. Cell. 75: 175-85. PMID 8402896  0.682
1993 Goga A, McLaughlin J, Pendergast AM, Parmar K, Muller A, Rosenberg N, Witte ON. Oncogenic activation of c-ABL by mutation within its last exon. Molecular and Cellular Biology. 13: 4967-75. PMID 8336729 DOI: 10.1128/Mcb.13.8.4967  0.622
1993 Muller AJ, Pendergast AM, Parmar K, Havlik MH, Rosenberg N, Witte ON. En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein tyrosine kinase. Proceedings of the National Academy of Sciences of the United States of America. 90: 3457-61. PMID 7682703 DOI: 10.1073/Pnas.90.8.3457  0.628
1993 Pendergast AM, Quilliam LA, Cripe LD, Bassing CH, Dai Z, Li N, Batzer A, Rabun KM, Der CJ, Schlessinger J, Gishizky ML. BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein Cell. 75: 175-185. DOI: 10.1016/S0092-8674(05)80094-7  0.661
1992 Muller AJ, Pendergast AM, Havlik MH, Puil L, Pawson T, Witte ON. A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction. Molecular and Cellular Biology. 12: 5087-93. PMID 1383690 DOI: 10.1128/Mcb.12.11.5087  0.551
1991 Muller AJ, Young JC, Pendergast AM, Pondel M, Landau NR, Littman DR, Witte ON. BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias. Molecular and Cellular Biology. 11: 1785-92. PMID 2005881 DOI: 10.1128/Mcb.11.4.1785  0.653
1991 Gishizky ML, McLaughlin J, Pendergast AM, Witte ON. The 5' non-coding region of the BCR/ABL oncogene augments its ability to stimulate the growth of immature lymphoid cells. Oncogene. 6: 1299-306. PMID 1886706  0.438
1991 Pendergast AM, Muller AJ, Havlik MH, Maru Y, Witte ON. BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner. Cell. 66: 161-71. PMID 1712671 DOI: 10.1016/0092-8674(91)90148-R  0.614
1991 Pendergast AM, Muller AJ, Havlik MH, Clark R, McCormick F, Witte ON. Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 88: 5927-31. PMID 1712111 DOI: 10.1073/Pnas.88.13.5927  0.706
1990 Lugo TG, Pendergast AM, Muller AJ, Witte ON. Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science (New York, N.Y.). 247: 1079-82. PMID 2408149 DOI: 10.1126/Science.2408149  0.683
1989 Ponzetto C, Wadewitz AG, Pendergast AM, Witte ON, Wolgemuth DJ. P150c-abl is detected in mouse male germ cells by an in vitro kinase assay and is associated with stage-specific phosphoproteins in haploid cells. Oncogene. 4: 685-90. PMID 2660070  0.559
1989 Pendergast AM, Clark R, Kawasaki ES, McCormick FP, Witte ON. Baculovirus expression of functional P210 BCR-ABL oncogene product. Oncogene. 4: 759-66. PMID 2499863  0.52
1988 Clark SS, McLaughlin J, Timmons M, Pendergast AM, Ben-Neriah Y, Dow LW, Crist W, Rovera G, Smith SD, Witte ON. Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL). Science (New York, N.Y.). 239: 775-7. PMID 3422516 DOI: 10.1126/Science.3422516  0.528
1987 Pendergast AM, Witte ON. Role of the ABL oncogene tyrosine kinase activity in human leukaemia. BaillièRe's Clinical Haematology. 1: 1001-20. PMID 3332851 DOI: 10.1016/S0950-3536(87)80036-7  0.651
1987 Pendergast AM, Traugh JA, Witte ON. Normal cellular and transformation-associated abl proteins share common sites for protein kinase C phosphorylation. Molecular and Cellular Biology. 7: 4280-9. PMID 3125421 DOI: 10.1128/Mcb.7.12.4280  0.779
1987 Pendergast AM, Venema RC, Traugh JA. Regulation of phosphorylation of aminoacyl-tRNA synthetases in the high molecular weight core complex in reticulocytes. The Journal of Biological Chemistry. 262: 5939-42. PMID 2437110  0.622
1986 Traugh JA, Pendergast AM. Regulation of protein synthesis by phosphorylation of ribosomal protein S6 and aminoacyl-tRNA synthetases. Progress in Nucleic Acid Research and Molecular Biology. 33: 195-230. PMID 3541042  0.611
1986 Pendergast AM, Traugh JA. Identification of three protein kinases which phosphorylate threonyl-tRNA synthetase from rat liver. Febs Letters. 206: 335-8. PMID 3019777 DOI: 10.1016/0014-5793(86)81007-9  0.725
1985 Pendergast AM, Traugh JA. Alteration of aminoacyl-tRNA synthetase activities by phosphorylation with casein kinase I. The Journal of Biological Chemistry. 260: 11769-74. PMID 3862666  0.701
1985 Pendergast AM, Traugh JA. Phosphorylation of aminoacyl-tRNA synthetase complex from rabbit reticulocytes by casein kinase I Federation Proceedings. 44: No. 3752.  0.665
Low-probability matches (unlikely to be authored by this person)
2023 Jones JK, Zhang H, Lyne AM, Cavalli FMG, Hassen WE, Stevenson K, Kornahrens R, Yang Y, Li S, Dell S, Reitman ZJ, Herndon JE, Hoj J, Pendergast AM, Thompson EM. ABL1 and ABL2 promote medulloblastoma leptomeningeal dissemination. Neuro-Oncology Advances. 5: vdad095. PMID 37781087 DOI: 10.1093/noajnl/vdad095  0.299
2004 Echarri A, Lai MJ, Robinson MR, Pendergast AM. Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels. Molecular and Cellular Biology. 24: 4979-93. PMID 15143189 DOI: 10.1128/Mcb.24.11.4979-4993.2004  0.296
2019 Khatri A, Gu JJ, McKernan CM, Xu X, Pendergast AM. ABL kinase inhibition sensitizes primary lung adenocarcinomas to chemotherapy by promoting tumor cell differentiation. Oncotarget. 10: 1874-1886. PMID 30956771 DOI: 10.18632/Oncotarget.26740  0.294
2020 Gu JJ, Hoj J, Rouse C, Pendergast AM. Mesenchymal stem cells promote metastasis through activation of an ABL-MMP9 signaling axis in lung cancer cells. Plos One. 15: e0241423. PMID 33119681 DOI: 10.1371/journal.pone.0241423  0.265
2019 Thompson E, Hassen W, Jones J, Hoj J, Pendergast AM. MEDU-02. ABL1 AND 2 PLAY A KEY ROLE IN MEDULLOBLASTOMA GROUP 3 AND 4 TUMOR PROLIFERATION AND LEPTOMENINGEAL DISSEMINATION Neuro-Oncology. 21: ii103-ii103. DOI: 10.1093/Neuonc/Noz036.162  0.258
2019 Khatri A, Gu JJ, McKernan CM, Xu X, Pendergast AM. Correction: ABL kinase inhibition sensitizes primary lung adenocarcinomas to chemotherapy by promoting tumor cell differentiation. Oncotarget. 10: 6045-6046. PMID 31666936 DOI: 10.18632/oncotarget.27258  0.256
2000 Onaitis M, Harpole D, Hartwig M, D’Amico T, Joshi M, Pendergast AM, Tyler D. Novel alterations of the adaptor protein Crkl in lung cancer Journal of the American College of Surgeons. 191: S71. DOI: 10.1016/S1072-7515(00)00593-7  0.254
2023 Chaudhary P, Xu X, Wang G, Hoj JP, Rampersad R, Asselin-Labat ML, Ting S, Kim W, Tamayo P, Pendergast AM, Onaitis M. Activation of KrasG12D in subset of alveolar Type II cells enhances cellular plasticity in lung adenocarcinoma. Cancer Research Communications. PMID 37882674 DOI: 10.1158/2767-9764.CRC-22-0408  0.25
2023 Thrash HL, Pendergast AM. Multi-Functional Regulation by YAP/TAZ Signaling Networks in Tumor Progression and Metastasis. Cancers. 15. PMID 37835395 DOI: 10.3390/cancers15194701  0.242
2019 Pendergast AM, McKernan C, Hoj J, Anders C, Force J, Fecci P. BSCI-22. IDENTIFICATION OF ACTIONABLE TYROSINE KINASE-REGULATED NETWORKS REQUIRED FOR LUNG AND BREAST CANCER BRAIN METASTASIS Neuro-Oncology Advances. 1: i5-i5. DOI: 10.1093/noajnl/vdz014.019  0.224
2021 Luttman JH, Hoj JP, Lin KH, Lin J, Gu JJ, Rouse C, Nichols AG, MacIver NJ, Wood KC, Pendergast AM. ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells. Cell Reports. 37: 109880. PMID 34706244 DOI: 10.1016/j.celrep.2021.109880  0.218
2019 Fecci PE, Champion CD, Hoj J, McKernan C, Goodwin CR, Kirkpatrick J, Anders CK, Pendergast AM, Sampson JH. The Evolving Modern Management of Brain Metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31213459 DOI: 10.1158/1078-0432.Ccr-18-1624  0.213
1999 Salgia R, Quackenbush E, Lin J, Souchkova N, Sattler M, Ewaniuk DS, Klucher KM, Daley GQ, Kraeft SK, Sackstein R, Alyea EP, von Andrian UH, Chen LB, Gutierrez-Ramos JC, Pendergast AM, et al. The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1alpha. Blood. 94: 4233-46. PMID 10590068  0.176
2022 Konkimalla A, Konishi S, Kobayashi Y, Kadur Lakshminarasimha Murthy P, Macadlo L, Mukherjee A, Elmore Z, Kim SJ, Pendergast AM, Lee PJ, Asokan A, Knudsen L, Bravo-Cordero JJ, Tata A, Tata PR. Multi-apical polarity of alveolar stem cells and their dynamics during lung development and regeneration. Iscience. 25: 105114. PMID 36185377 DOI: 10.1016/j.isci.2022.105114  0.172
2023 Bassil CF, Anderson GR, Mayro B, Askin KN, Winter PS, Gruber S, Hall TM, Hoj JP, Cerda-Smith C, Hutchinson HM, Killarney ST, Singleton KR, Qin L, Jubien-Girard K, Favreau C, ... ... Pendergast AM, et al. MCB-613 exploits a collateral sensitivity in drug resistant -mutant non-small cell lung cancer through covalent inhibition of KEAP1. Biorxiv : the Preprint Server For Biology. PMID 36711936 DOI: 10.1101/2023.01.17.524094  0.157
2021 Srinivasan ES, Tan AC, Anders CK, Pendergast AM, Sipkins DA, Ashley DM, Fecci PE, Khasraw M. Salting the soil: Targeting the microenvironment of brain metastases. Molecular Cancer Therapeutics. PMID 33402399 DOI: 10.1158/1535-7163.MCT-20-0579  0.136
2005 Croley AN, Zwetsloot KA, Westerkamp LM, Ryan NA, Pendergast AM, Hickner RC, Pofahl WE, Gavin TP. Lower capillarization, VEGF protein, and VEGF mRNA response to acute exercise in the vastus lateralis muscle of aged vs. young women. Journal of Applied Physiology (Bethesda, Md. : 1985). 99: 1872-9. PMID 16024519 DOI: 10.1152/Japplphysiol.00498.2005  0.089
1990 Selikowitz M, Sunman J, Pendergast A, Wright S. Fenfluramine in Prader-Willi syndrome: a double blind, placebo controlled trial. Archives of Disease in Childhood. 65: 112-4. PMID 2405783 DOI: 10.1136/adc.65.1.112  0.023
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