| Year |
Citation |
Score |
| 2019 |
Ruden JB, Quick KL, Gonzales ER, Shah AR, Park TS, Kennedy N, Dugan LL, Gidday JM. Reduction of Leukocyte Microvascular Adherence and Preservation of Blood-Brain Barrier Function by Superoxide-Lowering Therapies in a Piglet Model of Neonatal Asphyxia. Frontiers in Neurology. 10: 447. PMID 31118919 DOI: 10.3389/fneur.2019.00447 |
0.739 |
|
| 2018 |
Hardt JI, Perlmutter JS, Smith CJ, Quick KL, Wei L, Chakraborty SK, Dugan LL. Pharmacokinetics and Toxicology of the Neuroprotective e,e,e-Methanofullerene(60)-63-tris Malonic Acid [C] in Mice and Primates. European Journal of Drug Metabolism and Pharmacokinetics. PMID 29520718 DOI: 10.1007/S13318-018-0464-Z |
0.722 |
|
| 2014 |
Dugan LL, Tian L, Quick KL, Hardt JI, Karimi M, Brown C, Loftin S, Flores H, Moerlein SM, Polich J, Tabbal SD, Mink JW, Perlmutter JS. Carboxyfullerene neuroprotection postinjury in Parkinsonian nonhuman primates. Annals of Neurology. 76: 393-402. PMID 25043598 DOI: 10.1002/Ana.24220 |
0.753 |
|
| 2014 |
Chu W, Chepetan A, Zhou D, Shoghi KI, Xu J, Dugan LL, Gropler RJ, Mintun MA, Mach RH. Development of a PET radiotracer for non-invasive imaging of the reactive oxygen species, superoxide, in vivo. Organic & Biomolecular Chemistry. 12: 4421-31. PMID 24847866 DOI: 10.1039/C3Ob42379D |
0.336 |
|
| 2013 |
Dugan LL, You YH, Ali SS, Diamond-Stanic M, Miyamoto S, DeCleves AE, Andreyev A, Quach T, Ly S, Shekhtman G, Nguyen W, Chepetan A, Le TP, Wang L, Xu M, et al. AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function. The Journal of Clinical Investigation. 123: 4888-99. PMID 24135141 DOI: 10.1172/Jci66218 |
0.346 |
|
| 2013 |
Canzoniero LM, Granzotto A, Turetsky DM, Choi DW, Dugan LL, Sensi SL. nNOS(+) striatal neurons, a subpopulation spared in Huntington's Disease, possess functional NMDA receptors but fail to generate mitochondrial ROS in response to an excitotoxic challenge. Frontiers in Physiology. 4: 112. PMID 23720635 DOI: 10.3389/Fphys.2013.00112 |
0.393 |
|
| 2012 |
Ali SS, Hsiao M, Zhao HW, Dugan LL, Haddad GG, Zhou D. Hypoxia-adaptation involves mitochondrial metabolic depression and decreased ROS leakage. Plos One. 7: e36801. PMID 22574227 DOI: 10.1371/Journal.Pone.0036801 |
0.321 |
|
| 2012 |
Pamenter ME, Ali SS, Tang Q, Finley JC, Gu XQ, Dugan LL, Haddad GG. An in vitro ischemic penumbral mimic perfusate increases NADPH oxidase-mediated superoxide production in cultured hippocampal neurons. Brain Research. 1452: 165-72. PMID 22459046 DOI: 10.1016/J.Brainres.2012.03.004 |
0.409 |
|
| 2012 |
Hall DJ, Han SH, Chepetan A, Inui EG, Rogers M, Dugan LL. Dynamic optical imaging of metabolic and NADPH oxidase-derived superoxide in live mouse brain using fluorescence lifetime unmixing. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 23-32. PMID 21847136 DOI: 10.1038/Jcbfm.2011.119 |
0.386 |
|
| 2011 |
Ali SS, Young JW, Wallace CK, Gresack J, Jeste DV, Geyer MA, Dugan LL, Risbrough VB. Initial evidence linking synaptic superoxide production with poor short-term memory in aged mice. Brain Research. 1368: 65-70. PMID 21075081 DOI: 10.1016/J.Brainres.2010.11.009 |
0.38 |
|
| 2010 |
Ali SS, Marcondes MC, Bajova H, Dugan LL, Conti B. Metabolic depression and increased reactive oxygen species production by isolated mitochondria at moderately lower temperatures. The Journal of Biological Chemistry. 285: 32522-8. PMID 20716522 DOI: 10.1074/Jbc.M110.155432 |
0.365 |
|
| 2010 |
Douglas RM, Ryu J, Kanaan A, Del Carmen Rivero M, Dugan LL, Haddad GG, Ali SS. Neuronal death during combined intermittent hypoxia/hypercapnia is due to mitochondrial dysfunction. American Journal of Physiology. Cell Physiology. 298: C1594-602. PMID 20357179 DOI: 10.1152/Ajpcell.00298.2009 |
0.416 |
|
| 2009 |
Dugan LL, Ali SS, Shekhtman G, Roberts AJ, Lucero J, Quick KL, Behrens MM. IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase. Plos One. 4: e5518. PMID 19436757 DOI: 10.1371/Journal.Pone.0005518 |
0.713 |
|
| 2008 |
Behrens MM, Ali SS, Dugan LL. Interleukin-6 mediates the increase in NADPH-oxidase in the ketamine model of schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13957-66. PMID 19091984 DOI: 10.1523/Jneurosci.4457-08.2008 |
0.359 |
|
| 2008 |
Ali SS, Hardt JI, Dugan LL. SOD activity of carboxyfullerenes predicts their neuroprotective efficacy: a structure-activity study. Nanomedicine : Nanotechnology, Biology, and Medicine. 4: 283-94. PMID 18656425 DOI: 10.1016/J.Nano.2008.05.003 |
0.371 |
|
| 2008 |
Cuddihy SL, Ali SS, Musiek ES, Lucero J, Kopp SJ, Morrow JD, Dugan LL. Prolonged alpha-tocopherol deficiency decreases oxidative stress and unmasks alpha-tocopherol-dependent regulation of mitochondrial function in the brain. The Journal of Biological Chemistry. 283: 6915-24. PMID 18180306 DOI: 10.1074/Jbc.M702572200 |
0.759 |
|
| 2008 |
Quick KL, Ali SS, Arch R, Xiong C, Wozniak D, Dugan LL. A carboxyfullerene SOD mimetic improves cognition and extends the lifespan of mice. Neurobiology of Aging. 29: 117-28. PMID 17079053 DOI: 10.1016/J.Neurobiolaging.2006.09.014 |
0.76 |
|
| 2007 |
Behrens MM, Ali SS, Dao DN, Lucero J, Shekhtman G, Quick KL, Dugan LL. Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase. Science (New York, N.Y.). 318: 1645-7. PMID 18063801 DOI: 10.1126/Science.1148045 |
0.748 |
|
| 2006 |
Ali SS, Xiong C, Lucero J, Behrens MM, Dugan LL, Quick KL. Gender differences in free radical homeostasis during aging: shorter-lived female C57BL6 mice have increased oxidative stress. Aging Cell. 5: 565-74. PMID 17129217 DOI: 10.1111/J.1474-9726.2006.00252.X |
0.752 |
|
| 2006 |
Kim-Han JS, Kopp SJ, Dugan LL, Diringer MN. Perihematomal mitochondrial dysfunction after intracerebral hemorrhage. Stroke; a Journal of Cerebral Circulation. 37: 2457-62. PMID 16960094 DOI: 10.1161/01.Str.0000240674.99945.4E |
0.337 |
|
| 2005 |
Kim-Han JS, Dugan LL. Mitochondrial uncoupling proteins in the central nervous system. Antioxidants & Redox Signaling. 7: 1173-81. PMID 16115020 DOI: 10.1089/Ars.2005.7.1173 |
0.353 |
|
| 2005 |
Dugan LL, Quick KL. Reactive oxygen species and aging: evolving questions. Science of Aging Knowledge Environment : Sage Ke. 2005: pe20. PMID 15994214 DOI: 10.1126/Sageke.2005.26.Pe20 |
0.73 |
|
| 2004 |
Cuddihy SL, Musiek ES, Morrow JD, Dugan LL. Long-term vitamin E deficiency in mice decreases superoxide radical production in brain. Annals of the New York Academy of Sciences. 1031: 428-31. PMID 15753188 DOI: 10.1196/Annals.1331.064 |
0.762 |
|
| 2004 |
Ali SS, Hardt JI, Quick KL, Kim-Han JS, Erlanger BF, Huang TT, Epstein CJ, Dugan LL. A biologically effective fullerene (C60) derivative with superoxide dismutase mimetic properties. Free Radical Biology & Medicine. 37: 1191-202. PMID 15451059 DOI: 10.1016/J.Freeradbiomed.2004.07.002 |
0.754 |
|
| 2004 |
Dugan LL, Kim-Han JS. Astrocyte mitochondria in in vitro models of ischemia. Journal of Bioenergetics and Biomembranes. 36: 317-21. PMID 15377865 DOI: 10.1023/B:Jobb.0000041761.61554.44 |
0.381 |
|
| 2003 |
de Erausquin GA, Hyrc K, Dorsey DA, Mamah D, Dokucu M, Mascó DH, Walton T, Dikranian K, Soriano M, GarcÃa Verdugo JM, Goldberg MP, Dugan LL. Nuclear translocation of nuclear transcription factor-kappa B by alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors leads to transcription of p53 and cell death in dopaminergic neurons. Molecular Pharmacology. 63: 784-90. PMID 12644578 DOI: 10.1124/Mol.63.4.784 |
0.356 |
|
| 2002 |
Sheline CT, Choi EH, Kim-Han JS, Dugan LL, Choi DW. Cofactors of mitochondrial enzymes attenuate copper-induced death in vitro and in vivo. Annals of Neurology. 52: 195-204. PMID 12210790 DOI: 10.1002/Ana.10276 |
0.414 |
|
| 2001 |
Kim-Han JS, Reichert SA, Quick KL, Dugan LL. BMCP1: a mitochondrial uncoupling protein in neurons which regulates mitochondrial function and oxidant production. Journal of Neurochemistry. 79: 658-68. PMID 11701769 DOI: 10.1046/J.1471-4159.2001.00604.X |
0.747 |
|
| 2001 |
Reichert SA, Kim-Han JS, Dugan LL. The mitochondrial permeability transition pore and nitric oxide synthase mediate early mitochondrial depolarization in astrocytes during oxygen-glucose deprivation Journal of Neuroscience. 21: 6608-6616. PMID 11517250 DOI: 10.1523/Jneurosci.21-17-06608.2001 |
0.38 |
|
| 2001 |
Quick KL, Dugan LL. Superoxide stress identifies neurons at risk in a model of ataxia-telangiectasia. Annals of Neurology. 49: 627-35. PMID 11357953 DOI: 10.1002/Ana.1005 |
0.752 |
|
| 2001 |
Dugan LL, Lovett EG, Quick KL, Lotharius J, Lin TT, O'Malley KL. Fullerene-based antioxidants and neurodegenerative disorders. Parkinsonism & Related Disorders. 7: 243-246. PMID 11331193 DOI: 10.1016/S1353-8020(00)00064-X |
0.752 |
|
| 2001 |
Han BH, DeMattos RB, Dugan LL, Kim-Han JS, Brendza RP, Fryer JD, Kierson M, Cirrito J, Quick K, Harmony JA, Aronow BJ, Holtzman DM. Clusterin contributes to caspase-3-independent brain injury following neonatal hypoxia-ischemia. Nature Medicine. 7: 338-43. PMID 11231633 DOI: 10.1038/85487 |
0.753 |
|
| 2000 |
Quick KL, Hardt JI, Dugan LL. Rapid microplate assay for superoxide scavenging efficiency. Journal of Neuroscience Methods. 97: 139-44. PMID 10788668 DOI: 10.1016/S0165-0270(00)00179-5 |
0.737 |
|
| 2000 |
Lin TS, Dugan LL, Luh TY. EPR studies of free-radical reactions of carboxyfullerenes Applied Magnetic Resonance. 18: 321-331. DOI: 10.1007/Bf03162146 |
0.305 |
|
| 1999 |
Dugan LL, Kim JS, Zhang Y, Bart RD, Sun Y, Holtzman DM, Gutmann DH. Differential effects of cAMP in neurons and astrocytes. Role of B-raf. The Journal of Biological Chemistry. 274: 25842-8. PMID 10464325 DOI: 10.1074/Jbc.274.36.25842 |
0.316 |
|
| 1999 |
Ohlemiller KK, Wright JS, Dugan LL. Early elevation of cochlear reactive oxygen species following noise exposure. Audiology & Neuro-Otology. 4: 229-36. PMID 10436315 DOI: 10.1159/000013846 |
0.337 |
|
| 1999 |
Ohlemiller KK, Dugan LL. Elevation of reactive oxygen species following ischemia-reperfusion in mouse cochlea observed in vivo. Audiology & Neuro-Otology. 4: 219-28. PMID 10436314 DOI: 10.1159/000013845 |
0.377 |
|
| 1999 |
Behrens MM, Strasser U, Lobner D, Dugan LL. Neurotrophin-mediated potentiation of neuronal injury. Microscopy Research and Technique. 45: 276-84. PMID 10383120 DOI: 10.1002/(Sici)1097-0029(19990515/01)45:4/5<276::Aid-Jemt11>3.0.Co;2-4 |
0.314 |
|
| 1999 |
Lotharius J, Dugan LL, O'Malley KL. Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1284-93. PMID 9952406 DOI: 10.1523/Jneurosci.19-04-01284.1999 |
0.432 |
|
| 1998 |
Beetsch JW, Park TS, Dugan LL, Shah AR, Gidday JM. Xanthine oxidase-derived superoxide causes reoxygenation injury of ischemic cerebral endothelial cells. Brain Research. 786: 89-95. PMID 9554965 DOI: 10.1016/S0006-8993(97)01407-8 |
0.377 |
|
| 1997 |
Dugan LL, Turetsky DM, Du C, Lobner D, Wheeler M, Almli CR, Shen CK, Luh TY, Choi DW, Lin TS. Carboxyfullerenes as neuroprotective agents. Proceedings of the National Academy of Sciences of the United States of America. 94: 9434-9. PMID 9256500 DOI: 10.1073/Pnas.94.17.9434 |
0.4 |
|
| 1997 |
Dugan LL, Creedon DJ, Johnson EM, Holtzman DM. Rapid suppression of free radical formation by nerve growth factor involves the mitogen-activated protein kinase pathway Proceedings of the National Academy of Sciences of the United States of America. 94: 4086-4091. PMID 9108109 DOI: 10.1073/Pnas.94.8.4086 |
0.364 |
|
| 1997 |
Papadopoulos MC, Koumenis IL, Dugan LL, Giffard RG. Vulnerability to glucose deprivation injury correlates with glutathione levels in astrocytes Brain Research. 748: 151-156. PMID 9067456 DOI: 10.1016/S0006-8993(96)01293-0 |
0.332 |
|
| 1997 |
Goldberg MP, Strasser U, Dugan LL. Techniques for assessing neuroprotective drugs in vitro International Review of Neurobiology. 40: 69-93. PMID 8989617 DOI: 10.1016/S0074-7742(08)60716-3 |
0.34 |
|
| 1996 |
Dugan LL, Gabrielsen JK, Yu SP, Lin TS, Choi DW. Buckminsterfullerenol free radical scavengers reduce excitotoxic and apoptotic death of cultured cortical neurons. Neurobiology of Disease. 3: 129-35. PMID 9173920 DOI: 10.1006/Nbdi.1996.0013 |
0.41 |
|
| 1996 |
Klomp LW, Farhangrazi ZS, Dugan LL, Gitlin JD. Ceruloplasmin gene expression in the murine central nervous system. The Journal of Clinical Investigation. 98: 207-15. PMID 8690795 DOI: 10.1172/Jci118768 |
0.301 |
|
| 1995 |
Gwag BJ, Koh JY, Chen MM, Dugan LL, Behrens MM, Lobner D, Choi DW. BDNF or IGF-I potentiates free radical-mediated injury in cortical cell cultures. Neuroreport. 7: 93-6. PMID 8742425 DOI: 10.1097/00001756-199512000-00022 |
0.354 |
|
| 1995 |
Dugan LL, Lin TS, He YY, Hsu CY, Choi DW. Detection of free radicals by microdialysis/spin trapping epr following focal cerebral ischemia-reperfusion and a cautionary note on the stability of 5,5-dimethyl-1-pyrroline n-oxide (DMPO) Free Radical Research. 23: 27-32. PMID 7647917 DOI: 10.3109/10715769509064016 |
0.302 |
|
| 1995 |
Dugan LL, Bruno VMG, Amagasu SM, Giffard RG. Glia modulate the response of murine cortical neurons to excitotoxicity: Glia exacerbate AMPA neurotoxicity Journal of Neuroscience. 15: 4545-4555. PMID 7540679 DOI: 10.1523/Jneurosci.15-06-04545.1995 |
0.342 |
|
| 1995 |
Dugan LL, Sensi SL, Canzoniero LM, Handran SD, Rothman SM, Lin TS, Goldberg MP, Choi DW. Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 6377-88. PMID 7472402 DOI: 10.1523/Jneurosci.15-10-06377.1995 |
0.416 |
|
| 1994 |
Dugan LL, Choi DW. Excitotoxicity, free radicals, and cell membrane changes Annals of Neurology. 35: S17-S21. PMID 8185290 DOI: 10.1002/Ana.410350707 |
0.353 |
|
| 1994 |
Bruno VMG, Goldberg MP, Dugan LL, Giffard RG, Choi DW. Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose deprivation or excitatory amino acids Journal of Neurochemistry. 63: 1398-1406. PMID 7523591 DOI: 10.1046/J.1471-4159.1994.63041398.X |
0.338 |
|
| 1992 |
Monyer H, Giffard RG, Hartley DM, Dugan LL, Goldberg MP, Choi DW. Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin. Neuron. 8: 967-73. PMID 1350203 DOI: 10.1016/0896-6273(92)90211-U |
0.332 |
|
| 1985 |
Anderson DK, Demediuk P, Saunders RD, Dugan LL, Means ED, Horrocks LA. Spinal cord injury and protection. Annals of Emergency Medicine. 14: 816-21. PMID 3927795 DOI: 10.1016/S0196-0644(85)80064-0 |
0.3 |
|
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