Kunliang Guan - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Neuroscience Biology

355 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wang Y, Wu J, Chen H, Yang Y, Xiao C, Yi X, Shi C, Zhong K, He H, Li Y, Wu Z, Zhou G, Rao Q, Wang X, Zhou X, ... ... Guan K, et al. Genome-wide CRISPR-Cas9 screen identified KLF11 as a druggable suppressor for sarcoma cancer stem cells. Science Advances. 7. PMID 33571129 DOI: 10.1126/sciadv.abe3445  0.8
2020 Wu Z, Guan KL. Hippo Signaling in Embryogenesis and Development. Trends in Biochemical Sciences. PMID 32928629 DOI: 10.1016/J.Tibs.2020.08.008  0.48
2020 Lin Z, Xie R, Guan K, Zhang M. A WW Tandem-Mediated Dimerization Mode of SAV1 Essential for Hippo Signaling. Cell Reports. 32: 108118. PMID 32905778 DOI: 10.1016/J.Celrep.2020.108118  0.64
2020 Xia YK, Zeng YR, Zhang ML, Liu P, Liu F, Zhang H, He CX, Sun YP, Zhang JY, Zhang C, Song L, Ding C, Tang YJ, Yang Z, Yang C, ... ... Guan KL, et al. Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network. Protein & Cell. PMID 32683582 DOI: 10.1007/S13238-020-00754-2  0.8
2020 Cheng ZL, Zhang ML, Lin HP, Gao C, Song JB, Zheng Z, Li L, Zhang Y, Shen X, Zhang H, Huang Z, Zhan W, Zhang C, Hu X, Sun YP, ... ... Guan KL, et al. The Zscan4-Tet2 Transcription Nexus Regulates Metabolic Rewiring and Enhances Proteostasis to Promote Reprogramming. Cell Reports. 32: 107877. PMID 32668244 DOI: 10.1016/J.Celrep.2020.107877  0.8
2020 Li J, Chen X, Ding X, Cheng Y, Zhao B, Lai ZC, Al Hezaimi K, Hakem R, Guan KL, Wang CY. LATS2 Suppresses Oncogenic Wnt Signaling by Disrupting β-Catenin/BCL9 Interaction. Cell Reports. 31: 107792. PMID 32553156 DOI: 10.1016/j.celrep.2020.107792  0.8
2020 Zhu H, Blum RH, Bernareggi D, Ask EH, Wu Z, Hoel HJ, Meng Z, Wu C, Guan KL, Malmberg KJ, Kaufman DS. Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity. Cell Stem Cell. PMID 32531207 DOI: 10.1016/J.Stem.2020.05.008  0.72
2020 Fu V, Guan KL. Tales from the Cryptkeeper: New Roles for Lats1/2 in Wnt-driven Homeostasis. Cell Stem Cell. 26: 612-614. PMID 32386550 DOI: 10.1016/J.Stem.2020.04.011  0.48
2020 Li X, Wang TX, Huang X, Li Y, Sun T, Zang S, Guan KL, Xiong Y, Liu J, Yuan HX. Targeting ferroptosis alleviates methionine-choline deficient (MCD)-diet induced NASH by suppressing liver lipotoxicity. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 32145145 DOI: 10.1111/Liv.14428  0.8
2020 Hong AW, Meng Z, Plouffe SW, Lin Z, Zhang M, Guan KL. Critical roles of phosphoinositides and NF2 in Hippo pathway regulation. Genes & Development. PMID 32115406 DOI: 10.1101/Gad.333435.119  0.72
2020 Chen R, Xie R, Meng Z, Ma S, Guan KL. Publisher Correction: STRIPAK integrates upstream signals to initiate the Hippo kinase cascade. Nature Cell Biology. PMID 31896773 DOI: 10.1038/S41556-019-0460-9  0.72
2020 Wang X, Radhakrishnan A, Covey D, Horton J, Schwabe R, Tontonoz P, Guan K, Tabas I. Abstract B04: Hepatic cholesterol upregulates TAZ in nonalcoholic steatohepatitis Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-B04  0.56
2020 Zhong Y, Zhou X, Guan K, Zhang J. Constitutively Active Rheb Regulates Nuclear mTORC1 Activity and Function The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07130  0.64
2019 Koo JH, Plouffe SW, Meng Z, Lee DH, Yang D, Lim DS, Wang CY, Guan KL. Induction of AP-1 by YAP/TAZ contributes to cell proliferation and organ growth. Genes & Development. PMID 31831627 DOI: 10.1101/Gad.331546.119  0.8
2019 Chen R, Xie R, Meng Z, Ma S, Guan KL. STRIPAK integrates upstream signals to initiate the Hippo kinase cascade. Nature Cell Biology. PMID 31792377 DOI: 10.1038/S41556-019-0426-Y  0.72
2019 Shi H, Chapman NM, Wen J, Guy C, Long L, Dhungana Y, Rankin S, Pelletier S, Vogel P, Wang H, Peng J, Guan KL, Chi H. Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb. Immunity. PMID 31668641 DOI: 10.1016/J.Immuni.2019.10.001  0.36
2019 Wang TX, Liang JY, Zhang C, Xiong Y, Guan KL, Yuan HX. The oncometabolite 2-hydroxyglutarate produced by mutant IDH1 sensitizes cells to ferroptosis. Cell Death & Disease. 10: 755. PMID 31591388 DOI: 10.1038/S41419-019-1984-4  0.8
2019 Lin Z, Yang Z, Xie R, Ji Z, Guan K, Zhang M. Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity. Elife. 8. PMID 31486770 DOI: 10.7554/Elife.49439  0.64
2019 Li MT, Liang JY, Sun YP, Jin J, Xiong Y, Guan KL, Yuan HX. ELP3 acetyltransferase is phosphorylated and regulated by the oncogenic anaplastic lymphoma kinase (ALK). The Biochemical Journal. PMID 31341009 DOI: 10.1042/Bcj20190106  0.8
2019 Peng JR, Guan KL, Hong DY, Lin XH, Yang HM, Zhu YX. A special issue to mark the 90th Anniversary of College of Life Sciences, Zhejiang University. Journal of Zhejiang University. Science. B. 20: 371-372. PMID 31090262 DOI: 10.1631/Jzus.B1910002  0.44
2019 Li W, Aurandt J, Jürgensen C, Rao Y, Guan KL. Retraction: FAK and Src kinases are required for netrin-induced tyrosine phosphorylation of UNC5 (doi: 10.1242/jcs.02697). Journal of Cell Science. 132. PMID 30782981 DOI: 10.1242/Jcs.230342  0.84
2019 Zhang M, Wu J, Sun R, Tao X, Wang X, Kang Q, Wang H, Zhang L, Liu P, Zhang J, Xia Y, Zhao Y, Yang Y, Xiong Y, Guan KL, et al. SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress. Plos One. 14: e0211796. PMID 30759120 DOI: 10.1371/Journal.Pone.0211796  0.8
2019 Kim J, Guan KL. mTOR as a central hub of nutrient signalling and cell growth. Nature Cell Biology. 21: 63-71. PMID 30602761 DOI: 10.1038/S41556-018-0205-1  1
2019 Chen R, Plouffe SW, Guan KL. Determining the Phosphorylation Status of Hippo Components YAP and TAZ Using Phos-tag. Methods in Molecular Biology (Clifton, N.J.). 1893: 281-287. PMID 30565141 DOI: 10.1007/978-1-4939-8910-2_21  0.72
2019 Lin Z, Yang Z, Xie R, Ji Z, Guan K, Zhang M. Author response: Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity Elife. DOI: 10.7554/Elife.49439.038  0.64
2019 Jewell JL, Fu V, Hong AW, Yu F, Meng D, Melick CH, Wang H, Lam WM, Yuan H, Taylor SS, Guan K. Author response: GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor Elife. DOI: 10.7554/Elife.43038.019  0.72
2019 Zhu H, Blum R, Wu Z, Meng Z, Guan K, Kaufman DS. Deletion of CISH in Human Pluripotent Stem Cell-Derived Natural Killer Cells Enhances Anti-Tumor Activity Via Metabolic Reprogramming Blood. 134: 619-619. DOI: 10.1182/Blood-2019-124446  0.72
2018 Xu H, Xia YK, Li CJ, Zhang JY, Liu Y, Yi W, Qin ZY, Chen L, Shi ZF, Quan K, Yang ZX, Guan KL, Xiong Y, Ng HK, Ye D, et al. Rapid diagnosis of IDH1-mutated gliomas by 2-HG detection with gas chromatography mass spectrometry. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30573870 DOI: 10.1038/S41374-018-0163-Z  0.8
2018 Ma S, Meng Z, Chen R, Guan KL. The Hippo Pathway: Biology and Pathophysiology. Annual Review of Biochemistry. PMID 30566373 DOI: 10.1146/Annurev-Biochem-013118-111829  0.72
2018 Pan WW, Moroishi T, Koo JH, Guan KL. Cell type-dependent function of LATS1/2 in cancer cell growth. Oncogene. PMID 30531839 DOI: 10.1038/S41388-018-0610-8  0.68
2018 Zhang Z, Du J, Wang S, Shao L, Jin K, Li F, Wei B, Ding W, Fu P, van Dam H, Wang A, Jin J, Ding C, Yang B, Zheng M, ... ... Guan KL, et al. OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ. Molecular Cell. PMID 30472188 DOI: 10.1016/J.Molcel.2018.10.030  0.8
2018 Badur MG, Muthusamy T, Parker SJ, Ma S, McBrayer SK, Cordes T, Magana JH, Guan KL, Metallo CM. Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Sells. Cell Reports. 25: 1018-1026.e4. PMID 30355481 DOI: 10.1016/J.Celrep.2018.09.074  0.64
2018 Han H, Qi R, Zhou JJ, Ta AP, Yang B, Nakaoka HJ, Seo G, Guan KL, Luo R, Wang W. Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction. Molecular Cell. PMID 30293781 DOI: 10.1016/J.Molcel.2018.08.038  0.48
2018 Koo JH, Guan KL. Interplay between YAP/TAZ and Metabolism. Cell Metabolism. 28: 196-206. PMID 30089241 DOI: 10.1016/J.Cmet.2018.07.010  0.68
2018 Akgül S, Li Y, Zheng S, Kool M, Treisman DM, Li C, Wang Y, Gröbner S, Ikenoue T, Shen Y, Camelo-Piragua S, Tomasek G, Stark S, Guduguntla V, Gusella JF, ... Guan KL, et al. Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma. Cell Reports. 24: 463-478.e5. PMID 29996106 DOI: 10.1016/j.celrep.2018.06.050  0.8
2018 Ma S, Guan KL. Polycystic kidney disease: a Hippo connection. Genes & Development. 32: 737-739. PMID 29921661 DOI: 10.1101/Gad.316570.118  0.64
2018 Yu OM, Benitez JA, Plouffe SW, Ryback D, Klein A, Smith J, Greenbaum J, Delatte B, Rao A, Guan KL, Furnari FB, Chaim OM, Miyamoto S, Brown JH. YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity. Oncogene. PMID 29887596 DOI: 10.1038/S41388-018-0301-5  0.72
2018 Plouffe SW, Lin KC, Moore JL, Tan FE, Ma S, Ye Z, Qiu Y, Ren B, Guan KL. The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell. The Journal of Biological Chemistry. PMID 29802201 DOI: 10.1074/Jbc.Ra118.002715  0.72
2018 Li FL, Liu JP, Bao RX, Yan G, Feng X, Xu YP, Sun YP, Yan W, Ling ZQ, Xiong Y, Guan KL, Yuan HX. Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis. Nature Communications. 9: 508. PMID 29410405 DOI: 10.1038/S41467-018-02950-5  0.8
2018 Zhou B, Flodby P, Luo J, Castillo DR, Liu Y, Yu FX, McConnell A, Varghese B, Li G, Chimge NO, Sunohara M, Koss MN, Elatre W, Conti P, Liebler JM, ... ... Guan K, et al. Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis. The Journal of Clinical Investigation. PMID 29400695 DOI: 10.1172/Jci90429  0.64
2018 Liu MX, Jin L, Sun SJ, Liu P, Feng X, Cheng ZL, Liu WR, Guan KL, Shi YH, Yuan HX, Xiong Y. Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma. Oncogene. PMID 29335519 DOI: 10.1038/S41388-017-0070-6  0.8
2018 Fu V, Plouffe SW, Guan KL. The Hippo pathway in organ development, homeostasis, and regeneration. Current Opinion in Cell Biology. 49: 99-107. PMID 29316535 DOI: 10.1016/J.Ceb.2017.12.012  0.72
2018 Stoner SA, Yan M, Liu K, Shima T, Wang H, Arimoto K, Bejar R, Jamieson C, Guan K, Zhang D. Hippo Kinase Inactivation Contributes to Del(20q) Malignancies and Cooperates with JAK2-V617F to Promote Myelofibrosis in Mice Blood. 132: 99-99. DOI: 10.1182/Blood-2018-99-115591  0.44
2018 Zhu H, Blum R, Wu Z, Bahena A, Hoel HJ, Ask EH, Guan K, Malmberg K, Kaufman DS. Notch Activation Rescues Exhaustion in CISH-Deleted Human iPSC-Derived Natural Killer Cells to Promote In Vivo Persistence and Enhance Anti-Tumor Activity Blood. 132: 1279-1279. DOI: 10.1182/Blood-2018-99-112791  0.48
2017 Chen R, Guan KL. Colonic epithelium rejuvenation through YAP/TAZ. The Embo Journal. PMID 29282206 DOI: 10.15252/Embj.201798618  0.64
2017 Lin R, Mo Y, Zha H, Qu Z, Xie P, Zhu ZJ, Xu Y, Xiong Y, Guan KL. CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis. Molecular Cell. 68: 198-209.e6. PMID 28985504 DOI: 10.1016/J.Molcel.2017.09.008  0.8
2017 Mo Y, Lin R, Liu P, Tan M, Xiong Y, Guan KL, Yuan HX. SIRT7 deacetylates DDB1 and suppresses the activity of the CRL4 E3 ligase complexes. The Febs Journal. PMID 28886238 DOI: 10.1111/Febs.14259  0.8
2017 Gu Y, Albuquerque CP, Braas D, Zhang W, Villa GR, Bi J, Ikegami S, Masui K, Gini B, Yang H, Gahman TC, Shiau AK, Cloughesy TF, Christofk HR, Zhou H, ... Guan KL, et al. mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT. Molecular Cell. PMID 28648777 DOI: 10.1016/J.Molcel.2017.05.030  0.68
2017 Jin Y, Chen Y, Zhao S, Guan KL, Zhuang Y, Zhou W, Wu X, Xu T. DNA-PK facilitates piggyBac transposition by promoting paired-end complex formation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28645898 DOI: 10.1073/Pnas.1612980114  0.64
2017 Diao Y, Fang R, Li B, Meng Z, Yu J, Qiu Y, Lin KC, Huang H, Liu T, Marina RJ, Jung I, Shen Y, Guan KL, Ren B. A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells. Nature Methods. PMID 28417999 DOI: 10.1038/Nmeth.4264  0.72
2017 Zhang Q, Meng F, Chen S, Plouffe SW, Wu S, Liu S, Li X, Zhou R, Wang J, Zhao B, Liu J, Qin J, Zou J, Feng XH, Guan KL, et al. Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade. Nature Cell Biology. PMID 28346439 DOI: 10.1038/Ncb3496  0.72
2017 Wang Z, Liu P, Zhou X, Wang T, Feng X, Sun YP, Xiong Y, Yuan HX, Guan KL. Endothelin promotes colorectal tumorigenesis by activating YAP/TAZ. Cancer Research. PMID 28249901 DOI: 10.1158/0008-5472.Can-16-3229  0.8
2017 Ma S, Sun R, Jiang B, Gao J, Deng W, Liu P, He R, Cui J, Ji M, Yi W, Yang P, Wu X, Xiong Y, Qiu Z, Ye D, ... Guan KL, et al. L2hgdh deficiency accumulates L-2-hydroxyglutarate with progressive leukoencephalopathy and neurodegeneration. Molecular and Cellular Biology. PMID 28137912 DOI: 10.1128/Mcb.00492-16  0.8
2017 Ma X, Zhang S, He L, Rong Y, Wilz Brier L, Sun Q, Liu R, Fan W, Chen S, Yue Z, Kim J, Guan KL, Li D, Zhong Q. MTORC1-mediated NRBF2 phosphorylation functions as a switch for the class III PtdIns3K and autophagy. Autophagy. 0. PMID 28059666 DOI: 10.1080/15548627.2016.1269988  1
2017 Guan K, Shen J, Liu G, Zhao J, Zhou H, Jin W. Spray-evaporation assembled graphene oxide membranes for selective hydrogen transport Separation and Purification Technology. 174: 126-135. DOI: 10.1016/j.seppur.2016.10.012  0.52
2016 Hong AW, Meng Z, Yuan HX, Plouffe SW, Moon S, Kim W, Jho EH, Guan KL. Osmotic stress-induced phosphorylation by NLK at Ser128 activates YAP. Embo Reports. PMID 27979971 DOI: 10.15252/Embr.201642681  0.72
2016 Plouffe SW, Meng Z, Lin KC, Lin B, Hong AW, Chun JV, Guan KL. Characterization of Hippo Pathway Components by Gene Inactivation. Molecular Cell. 64: 993-1008. PMID 27912098 DOI: 10.1016/J.Molcel.2016.10.034  0.72
2016 Cao Y, Guan K, He X, Wei C, Zheng Z, Zhang Y, Ma S, Zhong H, Shi W. Yersinia YopJ negatively regulates IRF3-mediated antibacterial response through disruption of STING-mediated cytosolic DNA signaling. Biochimica Et Biophysica Acta. PMID 27742471 DOI: 10.1016/j.bbamcr.2016.10.004  0.44
2016 Dai XW, Wang C, Xu Y, Guan K, Su YX, Chen YM. Urinary Sodium and Potassium Excretion and Carotid Atherosclerosis in Chinese Men and Women. Nutrients. 8. PMID 27706075 DOI: 10.3390/nu8100612  0.8
2016 Wang KC, Yeh YT, Nguyen P, Limqueco E, Lopez J, Thorossian S, Guan KL, Li YJ, Chien S. Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27671657 DOI: 10.1073/Pnas.1613121113  1
2016 Wu J, Guan K, Hayek M, Restrepo-Coupe N, Wiedemann KT, Xu X, Wehr R, Christoffersen BO, Miao G, da Silva R, de Araujo AC, Oliviera RC, Camargo PB, Monson RK, Huete AR, et al. Partitioning controls on Amazon forest photosynthesis between environmental and biotic factors at hourly to inter-annual time scales. Global Change Biology. PMID 27644012 DOI: 10.1111/Gcb.13509  0.52
2016 Ma C, Song H, Yu L, Guan K, Hu P, Li Y, Xia X, Li J, Jiang S, Li F. miR-762 promotes porcine immature Sertoli cell growth via the ring finger protein 4 (RNF4) gene. Scientific Reports. 6: 32783. PMID 27596571 DOI: 10.1038/srep32783  0.6
2016 Guan K, Li LS, Yin J. Use of sIgE/T-IgE in Predicting Systemic Reactions: Retrospective Analysis of 54 Honeybee Venom Allergy Cases in North China. Chinese Medical Journal. 129: 2091-5. PMID 27569237 DOI: 10.4103/0366-6999.189056  0.52
2016 Zha Z, Han XR, Smith MD, Lei QY, Guan KL, Xiong Y. Hypertension-associated C825T polymorphism impairs the function of Gβ3 to target GRK2 ubiquitination. Cell Discovery. 2: 16005. PMID 27462452 DOI: 10.1038/Celldisc.2016.5  0.8
2016 Yang YW, Qian ZG, Li AR, Pu CX, Liu XL, Guan KY. Differentiation in fructification percentage between two morphs of Amomum tsaoko (Zingiberaceae). Breeding Science. 66: 391-5. PMID 27436949 DOI: 10.1270/jsbbs.13070  0.36
2016 Feng X, Liu P, Zhou X, Li MT, Li FL, Wang Z, Meng ZP, Sun YP, Yu Y, Xiong Y, Yuan HX, Guan KL. Thromboxane A2 Activates YAP/TAZ to Induce Vascular Smooth Muscle Cell Proliferation and Migration. The Journal of Biological Chemistry. PMID 27382053 DOI: 10.1074/Jbc.M116.739722  1
2016 Wu J, Chavana-Bryant C, Prohaska N, Serbin SP, Guan K, Albert LP, Yang X, van Leeuwen WJ, Garnello AJ, Martins G, Malhi Y, Gerard F, Oliviera RC, Saleska SR. Convergence in relationships between leaf traits, spectra and age across diverse canopy environments and two contrasting tropical forests. The New Phytologist. PMID 27381054 DOI: 10.1111/Nph.14051  0.44
2016 Liu X, Qi J, Xu X, Zeisberg M, Guan K, Zeisberg EM. Differentiation of functional endothelial cells from human induced pluripotent stem cells: A novel, highly efficient and cost effective method. Differentiation; Research in Biological Diversity. PMID 27266810 DOI: 10.1016/j.diff.2016.05.004  0.52
2016 Xu X, Medvigy D, Powers JS, Becknell JM, Guan K. Diversity in plant hydraulic traits explains seasonal and inter-annual variations of vegetation dynamics in seasonally dry tropical forests. The New Phytologist. PMID 27189787 DOI: 10.1111/Nph.14009  0.52
2016 Hong AW, Meng Z, Guan KL. The Hippo pathway in intestinal regeneration and disease. Nature Reviews. Gastroenterology & Hepatology. PMID 27147489 DOI: 10.1038/Nrgastro.2016.59  1
2016 Meng F, Zhou R, Wu S, Zhang Q, Jin Q, Zhou Y, Plouffe SW, Liu S, Song H, Xia Z, Zhao B, Ye S, Feng XH, Guan KL, Zou J, et al. Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation. Genes & Development. PMID 27125670 DOI: 10.1101/Gad.277533.116  1
2016 Zhou L, Wang F, Sun R, Chen X, Zhang M, Xu Q, Wang Y, Wang S, Xiong Y, Guan KL, Yang P, Yu H, Ye D. SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense. Embo Reports. PMID 27113762 DOI: 10.15252/Embr.201541643  1
2016 Fu V, Moroishi T, Guan KL. Glycoholics Anonymous: Cancer Sobers Up with mTORC1. Cancer Cell. 29: 432-4. PMID 27070696 DOI: 10.1016/J.Ccell.2016.03.016  1
2016 Huang C, Wu D, Khan FA, Jiao X, Guan K, Huo L. The GTPase SPAG-1 Orchestrates Meiotic Program by Dictating Meiotic Resumption and Cytoskeleton Architecture in Mouse Oocytes. Molecular Biology of the Cell. PMID 27053660 DOI: 10.1091/mbc.E16-02-0132  0.6
2016 Li H, Zhang D, Li X, Guan K, Yang H. Novel DREB A-5 subgroup transcription factors from desert moss (Syntrichia caninervis) confers multiple abiotic stress tolerance to yeast. Journal of Plant Physiology. PMID 27016184 DOI: 10.1016/j.jplph.2016.02.015  0.48
2016 Saleska SR, Wu J, Guan K, Araujo AC, Huete A, Nobre AD, Restrepo-Coupe N. Dry-season greening of Amazon forests. Nature. 531: E4-5. PMID 26983544 DOI: 10.1038/Nature16457  0.44
2016 Diao M, Li L, Ye M, Guan KP, Wei YD, Cheng W. Congenital anomaly rectified at birth: one-stage single-incision laparoscopic-assisted anorectoplasty for newborns with anorectal malformations and recto-urethral fistula. Surgical Endoscopy. PMID 26969663 DOI: 10.1007/s00464-016-4841-x  0.32
2016 Wu J, Albert LP, Lopes AP, Restrepo-Coupe N, Hayek M, Wiedemann KT, Guan K, Stark SC, Christoffersen B, Prohaska N, Tavares JV, Marostica S, Kobayashi H, Ferreira ML, Campos KS, et al. Leaf development and demography explain photosynthetic seasonality in Amazon evergreen forests. Science (New York, N.Y.). 351: 972-6. PMID 26917771 DOI: 10.1126/Science.Aad5068  0.44
2016 Zhang Y, Shan JL, Liu XM, Li F, Guan K, Sun TS. Comparison of the Dynesys Dynamic Stabilization System and Posterior Lumbar Interbody Fusion for Lumbar Degenerative Disease. Plos One. 11: e0148071. PMID 26824851 DOI: 10.1371/journal.pone.0148071  0.32
2016 Diao Y, Li B, Meng Z, Jung I, Lee A, Dixon J, Maliskova L, Guan KL, Shen Y, Ren B. A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9 mediated genetic screening. Genome Research. PMID 26813977 DOI: 10.1101/Gr.197152.115  0.56
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Guan KL, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.32
2016 Yuan HX, Guan KL. Structural insights of mTOR complex 1. Cell Research. PMID 26794870 DOI: 10.1038/Cr.2016.10  0.48
2016 Ma C, Song H, Guan K, Zhou J, Xia X, Li F. Characterization of swine testicular cell line as immature porcine Sertoli cell line. In Vitro Cellular & Developmental Biology. Animal. PMID 26744029 DOI: 10.1007/s11626-015-9994-8  0.6
2016 Meng Z, Moroishi T, Guan KL. Mechanisms of Hippo pathway regulation. Genes & Development. 30: 1-17. PMID 26728553 DOI: 10.1101/Gad.274027.115  1
2016 Han XR, Zha Z, Yuan HX, Feng X, Xia YK, Lei QY, Guan KL, Xiong Y. KDM2B/FBXL10 targets c-Fos for ubiquitylation and degradation in response to mitogenic stimulation. Oncogene. PMID 26725323 DOI: 10.1038/Onc.2015.482  0.48
2016 Guan KS, Liu G, Xu T, Xu YF. Choice of specimen types and calculation of Weibull parameters of small punch test based on Beremin model Suxing Gongcheng Xuebao/Journal of Plasticity Engineering. 23: 171-178. DOI: 10.3969/j.issn.1007-2012.2016.03.031  0.52
2016 Zhong Z, Ai B, Guan K, He R, Xiong L. Research on the theories and methods of wireless channels under high speed railway scenarios Beijing Jiaotong Daxue Xuebao/Journal of Beijing Jiaotong University. 40: 65-69. DOI: 10.11860/j.issn.1673-0291.2016.04.010  0.64
2016 Liu D, Zhou X, Ai B, Guan K, Li N. Evaluating the flickering complexity of the stored red blood cells using an efficient image processing method Beijing Jiaotong Daxue Xuebao/Journal of Beijing Jiaotong University. 40: 92-100. DOI: 10.11860/j.issn.1673-0291.2016.01.015  0.64
2016 Stoner SA, Andrews ET, Dekelver R, Weng S, Lo M, Guan K, Zhang D. RUNX1-ETO-Dependent Transcriptional Repression of RASSF2 Contributes to t(8;21) Leukemia through Evasion of MST1-Driven Apoptosis Signaling Blood. 128: 1547-1547. DOI: 10.1182/Blood.V128.22.1547.1547  0.4
2016 Ma K, Zhang Y, Zhang L, Guan K. Behavior of bolted joints with metal-to-metal contact type gaskets under bolting-up and loading conditions Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering. 230: 284-291. DOI: 10.1177/0954408914547931  0.52
2016 Ma K, Guan K, Cai R. Compression recovery performance of spring energized C-rings Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering. 230: 18-25. DOI: 10.1177/0954408914535572  0.52
2016 Wang Q, Ai B, Guan K, Matolak DW, He R, Zhou X. Ray-Based Statistical Propagation Modeling for Indoor Corridor Scenarios at 15 GHz International Journal of Antennas and Propagation. 2016. DOI: 10.1155/2016/2523913  0.64
2016 Wu J, Albert LP, Lopes AP, Restrepo-Coupe N, Hayek M, Wiedemann KT, Guan K, Stark SC, Christoffersen B, Prohaska N, Tavares JV, Marostica S, Kobayashi H, Ferreira ML, Campos KS, et al. Leaf development and demography explain photosynthetic seasonality in Amazon evergreen forests Science. 351: 972-976. DOI: 10.1126/science.add5068  0.44
2016 Abudureheman B, Zhang L, Liu H, Zhang D, Guan K. Achene germination of the spring ephemeroid species Carex physodes in the Gurbantunggut Desert Nordic Journal of Botany. 34: 228-234. DOI: 10.1111/njb.00931  0.4
2016 Fei D, Rodriguez-Pineiro J, Garcia-Naya JA, Castedo L, Guan K, Xiong L. TD-LTE downlink performance assessment in high speed scenarios Ieee Vehicular Technology Conference. 2016. DOI: 10.1109/VTCSpring.2016.7504501  0.64
2016 Guan K, Ai B, He R, Zhong Z, Xu T, Briso-Rodriguez C, Hrovat A. Stochastic modeling for extra propagation loss of tunnel curve Ieee Vehicular Technology Conference. 2016. DOI: 10.1109/VTCSpring.2016.7504491  0.64
2016 Li J, Ai B, He R, Guan K, Wang Q, Fei D, Zhong Z, Zhao Z, Miao D, Guan H. Measurement-based characterizations of indoor massive MIMO channels at 2 GHz, 4 GHz, and 6 GHz frequency bands Ieee Vehicular Technology Conference. 2016. DOI: 10.1109/VTCSpring.2016.7504341  0.64
2016 Zhang L, Ding J, Zhang B, Rodriguez CB, Guan K. Measurement and analysis of the broadband radio propagation in a high-speed railway station Ieee Vehicular Technology Conference. 2016. DOI: 10.1109/VTCSpring.2016.7504340  0.64
2016 Yang J, Ai B, Guan K, He D, He R, Zhang B, Zhong Z, Zhao Z, Miao D, Guan H. Deterministic modeling and stochastic analysis for channel in composite high-speed railway scenario Ieee Vehicular Technology Conference. 2016. DOI: 10.1109/VTCSpring.2016.7504193  0.64
2016 Li G, Ai B, Guan K, He R, Zhong Z, Hui B, Kim J. Channel characterization for mobile hotspot network in subway tunnels at 30 GHz band Ieee Vehicular Technology Conference. 2016. DOI: 10.1109/VTCSpring.2016.7504155  0.64
2016 Guan K, Ai B, Nicolás ML, Geise R, Möller A, Zhong Z, Kürner T. On the Influence of Scattering from Traffic Signs in Vehicle-to-X Communications Ieee Transactions On Vehicular Technology. 65: 5835-5849. DOI: 10.1109/TVT.2015.2476335  0.64
2016 Ai B, Guan K, Zhong Z, Lopez CF, Zhang L, Briso-Rodriguez C, He R. Measurement and Analysis of Extra Propagation Loss of Tunnel Curve Ieee Transactions On Vehicular Technology. 65: 1847-1858. DOI: 10.1109/TVT.2015.2425218  0.64
2016 Jin Y, Wen Y, Guan K. Toward Cost-Efficient Content Placement in Media Cloud: Modeling and Analysis Ieee Transactions On Multimedia. 18: 807-819. DOI: 10.1109/TMM.2016.2537199  0.6
2016 Guan K, Ai B, Fricke A, He D, Zhong Z, Matolak DW, Kurner T. Excess Propagation Loss Modeling of Semiclosed Obstacles for Intelligent Transportation System Ieee Transactions On Intelligent Transportation Systems. DOI: 10.1109/TITS.2016.2515663  0.64
2016 He R, Ai B, Wang G, Guan K, Zhong Z, Molisch AF, Briso-Rodriguez C, Oestges CP. High-Speed Railway Communications: From GSM-R to LTE-R Ieee Vehicular Technology Magazine. 11: 49-58. DOI: 10.1109/Mvt.2016.2564446  0.64
2016 Ma YC, Wang L, Guan KM, Jiang T, Cao XW, Chen QD, Sun HB. Silicon-Based Suspended Structure Fabricated by Femtosecond Laser Direct Writing and Wet Etching Ieee Photonics Technology Letters. 28: 1605-1608. DOI: 10.1109/LPT.2016.2554203  0.36
2016 Zhang L, Briso C, Fernandez JRO, Alonso JI, Rodríguez C, García-Loygorri JM, Guan K. Delay Spread and Electromagnetic Reverberation in Subway Tunnels and Stations Ieee Antennas and Wireless Propagation Letters. 15: 585-588. DOI: 10.1109/LAWP.2015.2462022  0.64
2016 Yao WG, Guan KM, Tian ZN, Xu JJ, Chen QD, Sun HB. Mode-selecting micrograting cavity laser Journal of Lightwave Technology. 34: 4142-4146. DOI: 10.1109/JLT.2016.2592101  0.36
2016 Guan K, Winzer PJ, Tulino AM, Soljanin E. Physical layer security of space-division multiplexed fiber-optic communication systems in the presence of multiple eavesdroppers 2015 Ieee Global Communications Conference, Globecom 2015. DOI: 10.1109/GLOCOM.2014.7417679  0.6
2016 Li G, Ai B, Guan K, He R, Zhong Z, Tian L, Dou J. Path loss modeling and fading analysis for channels with various antenna setups in tunnels at 30 GHz band 2016 10th European Conference On Antennas and Propagation, Eucap 2016. DOI: 10.1109/EuCAP.2016.7481790  0.64
2016 Yang J, Ai B, Guan K, He R, Zhong Z, Zhao Z, Miao D, Guan H. On the influence of mobility: Doppler spread and fading analysis in rapidly time-varying channels 2016 10th European Conference On Antennas and Propagation, Eucap 2016. DOI: 10.1109/EuCAP.2016.7481787  0.64
2016 Zhang L, Ding J, Zhang B, Rodriguez CB, Guan K. Experimental study on wave propagation in railway cuttings at 950 MHz and 2150 MHz 2016 10th European Conference On Antennas and Propagation, Eucap 2016. DOI: 10.1109/EuCAP.2016.7481739  0.64
2016 Guan K, Ai B, Kurner T, He R, Moller A, Zhangdui Z. Integrating composite urban furniture into ray-tracing simulator for 5G small cells and outdoor device-to-device communications 2016 10th European Conference On Antennas and Propagation, Eucap 2016. DOI: 10.1109/EuCAP.2016.7481737  0.64
2016 Zhou X, Zhong Z, Bian X, Ai B, He Z, Liu K, Guan K, He R, Zhang B, Wu J. On measurement uncertainty introduced by instruments in frequency domain channel measurement systems 2016 10th European Conference On Antennas and Propagation, Eucap 2016. DOI: 10.1109/EuCAP.2016.7481329  0.64
2016 Zhang B, Zhong Z, Zhou X, Guan K, He R. Path loss characteristics of indoor radio channels at 15 GHz 2016 10th European Conference On Antennas and Propagation, Eucap 2016. DOI: 10.1109/EuCAP.2016.7481177  0.64
2016 Fei D, He R, AI B, Zhang B, Guan K, Zhong Z. Massive MIMO channel measurements and analysis at 3.33 GHz Proceedings of the 2015 10th International Conference On Communications and Networking in China, Chinacom 2015. 194-198. DOI: 10.1109/CHINACOM.2015.7497936  0.64
2016 Wang D, Guan K, Bai Z, Liu F. Facile preparation of acid-resistant magnetite particles for removal of Sb(III) from strong acidic solution Science and Technology of Advanced Materials. 17: 80-88. DOI: 10.1080/14686996.2016.1145530  0.56
2016 Wu S, Xu T, Song M, Guan K. Mechanical properties characterisation of welded joint of austenitic stainless steel using instrumented indentation technique Materials At High Temperatures. 33: 270-275. DOI: 10.1080/09603409.2016.1187463  0.52
2016 Li Y, Guan K, Hu Z. Fiber optic displacement measurement model based on finite reflective surface Optics and Laser Technology. 84: 32-39. DOI: 10.1016/j.optlastec.2016.03.031  0.72
2016 Yang Q, Guan K, Qiu X, Zhang D, Lv S, Bu F, Zhang Y, Liu X, Meng J. Structures of Al2Sm phase in a high-pressure die-cast Mg–4Al–4Sm–0.3Mn alloy Materials Science and Engineering A. 675: 396-402. DOI: 10.1016/j.msea.2016.08.066  0.44
2016 Guan K, Jia L, Kong B, Yuan S, Zhang H. Study of the fracture mechanism of NbSS/Nb5Si3 in situ composite: Based on a mechanical characterization of interfacial strength Materials Science and Engineering A. 663: 98-107. DOI: 10.1016/j.msea.2016.03.110  0.44
2016 Guan K, Qin W, Liu Y, Yin X, Peng C, Lv M, Sun Q, Wu J. Evolution of porosity, pore size and permeate flux of ceramic membranes during sintering process Journal of Membrane Science. 520: 166-175. DOI: 10.1016/j.memsci.2016.07.023  0.44
2016 Shen J, Liu G, Huang K, Li Q, Guan K, Li Y, Jin W. UiO-66-polyether block amide mixed matrix membranes for CO2 separation Journal of Membrane Science. 513: 155-165. DOI: 10.1016/j.memsci.2016.04.045  0.52
2016 Li Y, Shen J, Guan K, Liu G, Zhou H, Jin W. PEBA/ceramic hollow fiber composite membrane for high-efficiency recovery of bio-butanol via pervaporation Journal of Membrane Science. 510: 338-347. DOI: 10.1016/j.memsci.2016.03.013  0.52
2016 Yang Q, Guan K, Bu F, Zhang Y, Qiu X, Zheng T, Liu X, Meng J. Microstructures and tensile properties of a high-strength die-cast Mg-4Al-2RE-2Ca-0.3Mn alloy Materials Characterization. 113: 180-188. DOI: 10.1016/j.matchar.2016.01.024  0.44
2016 Bu F, Yang Q, Guan K, Qiu X, Zhang D, Sun W, Zheng T, Cui X, Sun S, Tang Z, Liu X, Meng J. Study on the mutual effect of La and Gd on microstructure and mechanical properties of Mg-Al-Zn extruded alloy Journal of Alloys and Compounds. 688: 1241-1250. DOI: 10.1016/J.Jallcom.2016.07.037  0.44
2016 Kong B, Jia L, Zhang H, Sha J, Shi S, Guan K. Microstructure, mechanical properties and fracture behavior of Nb with minor Si addition International Journal of Refractory Metals and Hard Materials. 58: 84-91. DOI: 10.1016/j.ijrmhm.2016.04.004  0.44
2016 Zou B, Guan KS, Wu SB. Determination of area reduction rate by continuous ball indentation test International Journal of Pressure Vessels and Piping. 139: 220-227. DOI: 10.1016/j.ijpvp.2016.02.023  0.52
2016 Zou B, Guan KS, Wu SB. Determination of area reduction rate by spherical indentation test International Journal of Pressure Vessels and Piping. DOI: 10.1016/j.ijpvp.2016.02.012  0.52
2016 Sui X, Kuss P, Li W, Yang M, Guan K, Li A. Identity and distribution of weedy Pedicularis kansuensis Maxim. (Orobanchaceae) in Tianshan Mountains of Xinjiang: morphological, anatomical and molecular evidence Journal of Arid Land. 8: 453-461. DOI: 10.1007/s40333-016-0004-0  0.36
2016 Zhong J, Xu T, Guan K, Huang L. Evaluation of Ductile Damage Parameters under High Stress Triaxiality Experimental Mechanics. 1-4. DOI: 10.1007/s11340-016-0224-4  0.52
2016 Zhong J, Xu T, Guan K, Zou B. Determination of Ductile Damage Parameters Using Hybrid Particle Swarm Optimization Experimental Mechanics. 1-11. DOI: 10.1007/s11340-016-0141-6  0.52
2016 Guan K, Ai B, Fricke A, He D, Zhong Z, Matolak DW, Kürner T. Excess Propagation Loss of Semi-Closed Obstacles for Inter/Intra-Device Communications in the Millimeter-Wave Range Journal of Infrared, Millimeter, and Terahertz Waves. 1-15. DOI: 10.1007/s10762-016-0251-3  0.64
2016 Sun P, Feng G, Guan K, Zhang Y. Comparison between operational capability of PDT and tetra technologies: A summary Lecture Notes in Electrical Engineering. 348: 179-187. DOI: 10.1007/978-81-322-2580-5_18  0.44
2016 Shen J, Zhang M, Liu G, Guan K, Jin W. Size effects of graphene oxide on mixed matrix membranes for CO2 separation Aiche Journal. 62: 2843-2852. DOI: 10.1002/aic.15260  0.52
2016 Guan K, Cho J, Winzer PJ. A computationally efficient shift-register based information scrambling approach to physical layer security in MIMO-SDM systems 2016 Optical Fiber Communications Conference and Exhibition, Ofc 2016 0.6
2016 Guan K, Hao Y, Hu Z. Preparation of high performance piezoelectric ceramic target for magnetoelectric composite films Yadian Yu Shengguang/Piezoelectrics and Acoustooptics. 38: 16-18 and 23.  0.32
2015 Lyubasyuk V, Ouyang H, Yu FX, Guan KL, Zhang K. YAP inhibition blocks uveal melanogenesis driven by GNAQ or GNA11 mutations. Molecular & Cellular Oncology. 2: e970957. PMID 27308390 DOI: 10.4161/23723548.2014.970957  0.64
2015 Zheng Z, Wei C, Guan K, Yuan Y, Zhang Y, Ma S, Cao Y, Wang F, Zhong H, He X. Bacterial E3 Ubiquitin Ligase IpaH4.5 of Shigella flexneri Targets TBK1 To Dampen the Host Antibacterial Response. Journal of Immunology (Baltimore, Md. : 1950). PMID 26700764 DOI: 10.4049/jimmunol.1501045  0.44
2015 Wang P, Wu J, Ma S, Zhang L, Yao J, Hoadley KA, Wilkerson MD, Perou CM, Guan KL, Ye D, Xiong Y. Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents. Cell Reports. PMID 26686626 DOI: 10.1016/J.Celrep.2015.11.029  1
2015 Hansen CG, Ng YL, Lam WM, Plouffe SW, Guan KL. The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1. Cell Research. PMID 26611634 DOI: 10.1038/Cr.2015.140  0.72
2015 Yuan HX, Wang Z, Yu FX, Li F, Russell RC, Jewell JL, Guan KL. NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition. Genes & Development. 29: 2362-76. PMID 26588989 DOI: 10.1101/Gad.265116.115  1
2015 Yu FX, Zhao B, Guan KL. Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer. Cell. 163: 811-28. PMID 26544935 DOI: 10.1016/J.Cell.2015.10.044  1
2015 Wang S, Jiang B, Zhang T, Liu L, Wang Y, Wang Y, Chen X, Lin H, Zhou L, Xia Y, Chen L, Yang C, Xiong Y, Ye D, Guan KL. Correction: Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Plos Biology. 13: e1002287. PMID 26539968 DOI: 10.1371/Journal.Pbio.1002287  1
2015 Yuan HX, Guan KL. The SIN1-PH Domain Connects mTORC2 to PI3K. Cancer Discovery. 5: 1127-9. PMID 26526694 DOI: 10.1158/2159-8290.Cd-15-1125  1
2015 Shi WQ, Liu J, Cao Y, Zhu YY, Guan K, Chen YM. Association of dietary and serum vitamin E with bone mineral density in middle-aged and elderly Chinese adults: a cross-sectional study. The British Journal of Nutrition. 1-8. PMID 26507315 DOI: 10.1017/S0007114515004134  0.8
2015 Ma T, Li J, Xu Y, Yu C, Xu T, Wang H, Liu K, Cao N, Nie BM, Zhu SY, Xu S, Li K, Wei WG, Wu Y, Guan KL, et al. Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming. Nature Cell Biology. PMID 26502054 DOI: 10.1038/Ncb3256  0.4
2015 Guan K, Berry J, Zhang Y, Joiner J, Guanter L, Badgley G, Lobell DB. Improving the monitoring of crop productivity using spaceborne solar-induced fluorescence. Global Change Biology. PMID 26490834 DOI: 10.1111/Gcb.13136  0.44
2015 Meng Z, Moroishi T, Mottier-Pavie V, Plouffe SW, Hansen CG, Hong AW, Park HW, Mo JS, Lu W, Lu S, Flores F, Yu FX, Halder G, Guan KL. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nature Communications. 6: 8357. PMID 26437443 DOI: 10.1038/ncomms9357  1
2015 Nemazanyy I, Montagnac G, Russell RC, Morzyglod L, Burnol AF, Guan KL, Pende M, Panasyuk G. Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. Nature Communications. 6: 8283. PMID 26387534 DOI: 10.1038/Ncomms9283  1
2015 Wang S, Jiang B, Zhang T, Liu L, Wang Y, Wang Y, Chen X, Lin H, Zhou L, Xia Y, Chen L, Yang C, Xiong Y, Ye D, Guan KL. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Plos Biology. 13: e1002243. PMID 26356530 DOI: 10.1371/Journal.Pbio.1002243  1
2015 Ha J, Guan KL, Kim J. AMPK and autophagy in glucose/glycogen metabolism. Molecular Aspects of Medicine. PMID 26297963 DOI: 10.1016/J.Mam.2015.08.002  1
2015 Park HW, Kim YC, Yu B, Moroishi T, Mo JS, Plouffe SW, Meng Z, Lin KC, Yu FX, Alexander CM, Wang CY, Guan KL. Alternative Wnt Signaling Activates YAP/TAZ. Cell. 162: 780-94. PMID 26276632 DOI: 10.1016/J.Cell.2015.07.013  1
2015 Gong R, Hong AW, Plouffe SW, Zhao B, Liu G, Yu FX, Xu Y, Guan KL. Opposing roles of conventional and novel PKC isoforms in Hippo-YAP pathway regulation. Cell Research. PMID 26206313 DOI: 10.1038/Cr.2015.88  0.56
2015 Huang K, Li Q, Liu G, Shen J, Guan K, Jin W. A ZIF-71 Hollow Fiber Membrane Fabricated by Contra-Diffusion. Acs Applied Materials & Interfaces. 7: 16157-60. PMID 26193169 DOI: 10.1021/acsami.5b04991  0.52
2015 Song H, Zhu L, Li Y, Ma C, Guan K, Xia X, Li F. Exploiting RNA-sequencing data from the porcine testes to identify the key genes involved in spermatogenesis in Large White pigs. Gene. PMID 26192463 DOI: 10.1016/j.gene.2015.07.057  0.6
2015 Li W, Guan KL. The Down syndrome cell adhesion molecule (DSCAM) interacts with and activates Pak. The Journal of Biological Chemistry. 290: 14797. PMID 26048998 DOI: 10.1074/Jbc.A115.401878  0.84
2015 Hansen CG, Moroishi T, Guan KL. YAP and TAZ: a nexus for Hippo signaling and beyond. Trends in Cell Biology. PMID 26045258 DOI: 10.1016/J.Tcb.2015.05.002  1
2015 Qi Q, Li DY, Luo HR, Guan KL, Ye K. Netrin-1 exerts oncogenic activities through enhancing Yes-associated protein stability. Proceedings of the National Academy of Sciences of the United States of America. 112: 7255-60. PMID 26039999 DOI: 10.1073/pnas.1505917112  1
2015 Li L, Guan K. [Quality of life in 164 allergic rhinitis patients caused by different aeroallergens]. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery. 29: 226-9. PMID 26012293  0.48
2015 Yang X, Wang C, Xu C, Yan Z, Wei C, Guan K, Ma S, Cao Y, Liu L, Zou D, He X, Zhang B, Ma Q, Zheng Z. miR-526a regulates apoptotic cell growth in human carcinoma cells. Molecular and Cellular Biochemistry. PMID 26002288 DOI: 10.1007/s11010-015-2455-6  0.44
2015 Zha Z, Han X, Smith MD, Liu Y, Giguère PM, Kopanja D, Raychaudhuri P, Siderovski DP, Guan KL, Lei QY, Xiong Y. A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation. Molecular Cell. 58: 794-803. PMID 25982117 DOI: 10.1016/J.Molcel.2015.04.017  1
2015 Sui XL, Huang W, Li YJ, Guan KY, Li AR. Host shoot clipping depresses the growth of weedy hemiparasitic Pedicularis kansuensis. Journal of Plant Research. 128: 563-72. PMID 25956077 DOI: 10.1007/s10265-015-0727-6  0.48
2015 Yang Y, Li L, Guan K, Yang X. Taxonomy of Fissocantharis Pic (Coleoptera, Cantharidae) from Guangxi, China, with descriptions of six new species. Zookeys. 95-123. PMID 25878532 DOI: 10.3897/zookeys.489.9153  0.32
2015 Vikis HG, Guan KL. Glutathione-S-transferase (GST)-fusion based assays for studying protein-protein interactions. Methods in Molecular Biology (Clifton, N.J.). 1278: 353-64. PMID 25859961 DOI: 10.1007/978-1-4939-2425-7_22  0.52
2015 Zhou Q, Li L, Zhao B, Guan KL. The hippo pathway in heart development, regeneration, and diseases. Circulation Research. 116: 1431-47. PMID 25858067 DOI: 10.1161/Circresaha.116.303311  1
2015 Kim JS, Ro SH, Kim M, Park HW, Semple IA, Park H, Cho US, Wang W, Guan KL, Karin M, Lee JH. Sestrin2 inhibits mTORC1 through modulation of GATOR complexes. Scientific Reports. 5: 9502. PMID 25819761 DOI: 10.1038/Srep09502  0.72
2015 Cao Y, Wang C, Guan K, Xu Y, Su YX, Chen YM. Association of magnesium in serum and urine with carotid intima-media thickness and serum lipids in middle-aged and elderly Chinese: a community-based cross-sectional study. European Journal of Nutrition. PMID 25750058 DOI: 10.1007/s00394-015-0839-8  0.8
2015 Taniguchi K, Wu LW, Grivennikov SI, de Jong PR, Lian I, Yu FX, Wang K, Ho SB, Boland BS, Chang JT, Sandborn WJ, Hardiman G, Raz E, Maehara Y, Yoshimura A, ... ... Guan KL, et al. A gp130-Src-YAP module links inflammation to epithelial regeneration. Nature. 519: 57-62. PMID 25731159 DOI: 10.1038/Nature14228  0.64
2015 Plouffe SW, Hong AW, Guan KL. Disease implications of the Hippo/YAP pathway. Trends in Molecular Medicine. 21: 212-22. PMID 25702974 DOI: 10.1016/J.Molmed.2015.01.003  1
2015 Jewell JL, Flores F, Guan KL. Micro(RNA) managing by mTORC1. Molecular Cell. 57: 575-6. PMID 25699705 DOI: 10.1016/J.Molcel.2015.02.006  1
2015 Kim YC, Guan KL. mTOR: a pharmacologic target for autophagy regulation. The Journal of Clinical Investigation. 125: 25-32. PMID 25654547 DOI: 10.1172/Jci73939  1
2015 Gao G, Yu Z, Yan J, Li J, Shen S, Jia B, Guan K, Gao X, Kan Q. Poly (ADP‑ribose) polymerase‑ and cytochrome c‑mediated apoptosis induces hepatocyte injury in a rat model of hyperammonia‑induced hepatic failure. Molecular Medicine Reports. 11: 4211-9. PMID 25634059 DOI: 10.3892/mmr.2015.3281  0.44
2015 Jewell JL, Kim YC, Russell RC, Yu FX, Park HW, Plouffe SW, Tagliabracci VS, Guan KL. Metabolism. Differential regulation of mTORC1 by leucine and glutamine. Science (New York, N.Y.). 347: 194-8. PMID 25567907 DOI: 10.1126/Science.1259472  1
2015 Sun R, Luo Y, Li J, Wang Q, Chen X, Guan K, Yu Z. Ammonium chloride inhibits autophagy of hepatocellular carcinoma cells through SMAD2 signaling Tumor Biology. 36: 1173-1177. PMID 25342595 DOI: 10.1007/s13277-014-2699-x  0.44
2015 Yu FX, Meng Z, Plouffe SW, Guan KL. Hippo pathway regulation of gastrointestinal tissues. Annual Review of Physiology. 77: 201-27. PMID 25293527 DOI: 10.1146/Annurev-Physiol-021014-071733  1
2015 Liu G, Yu FX, Kim YC, Meng Z, Naipauer J, Looney DJ, Liu X, Gutkind JS, Mesri EA, Guan KL. Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway. Oncogene. 34: 3536-46. PMID 25195862 DOI: 10.1038/Onc.2014.281  0.36
2015 Chen YM, Liu Y, Liu YH, Wang X, Guan K, Zhu HL. Higher serum concentrations of betaine rather than choline is associated with better profiles of DXA-derived body fat and fat distribution in Chinese adults. International Journal of Obesity (2005). 39: 465-71. PMID 25152241 DOI: 10.1038/ijo.2014.158  0.56
2015 Guan K. Wright type multiplicatively convex functions Mathematical Inequalities and Applications. 18: 389-399. DOI: 10.7153/mia-18-28  0.48
2015 Li WJ, Guan KY. Validation of the Name Artemisia rutifolia var. Ruoqiangensis (Asteraceae) Annales Botanici Fennici. 52: 301-302. DOI: 10.5735/085.052.0504  0.64
2015 Su J, Guan K, Wang J, Yang Y. Significance of hind wing morphology in distinguishing genera and species of cantharid beetles with a geometric morphometric analysis Zookeys. 11-25. DOI: 10.3897/zookeys.502.9191  0.32
2015 Ding J, Jiang W, Zhong Z, Guan K, Ai B. Measurement and analysis of Doppler shift for high-speed rail scenario High Technology Letters. 21: 192-199. DOI: 10.3772/j.issn.1006-6748.2015.02.011  0.64
2015 Guo C, Cao P, Xue X, Wang B, Guan K, Guan Y, Zheng S. A case of tubulocystic carcinoma of kidney and literature review Cancer Research and Clinic. 27: 831-834. DOI: 10.3760/cma.j.issn.1006-9801.2015.12.011  0.36
2015 Liu S, Zhang L, Yin X, Liu Y, Cheng L, Li H, Zhao C, Guan K. The comparison of microstructure and oxidation behaviors of (SiC-C)/PyC/SiC and C/PyC<sup>HT</sup>/SiC composites in air Science and Engineering of Composite Materials. 22: 417-423. DOI: 10.1515/secm-2013-0072  0.44
2015 Guan K, Wang Q. Asymptotic Behavior of Solutions of a Nonlinear Neutral Generalized Pantograph Equation with Impulses Mathematica Slovaca. 65: 1049-1062. DOI: 10.1515/ms-2015-0072  0.48
2015 Shen RL, Guan K, Fang K. Probability distribution of random variables of impact coefficient in numerical simulation of vehicle-bridge coupled vibration Zhendong Yu Chongji/Journal of Vibration and Shock. 34: 123-128. DOI: 10.13465/j.cnki.jvs.2015.18.021  0.32
2015 Yuan CS, Shen RL, Zhou LY, Li WD, Guan K. Nonlinear free vibration of inclined cables taking into account the effect of chord component of gravity Zhendong Yu Chongji/Journal of Vibration and Shock. 34: 201-206. DOI: 10.13465/j.cnki.jvs.2015.12.034  0.32
2015 Feng X, Xu T, Qin Y, Guan K. Determination of creep properties of P91 by small punch testing Materials At High Temperatures. 32: 355-362. DOI: 10.1179/1878641314Y.0000000025  0.52
2015 Guo A, Zhao J, Li J, Li F, Guan K. Forming parameters optimisation of biomass cushion packaging material by orthogonal test Materials Research Innovations. 19: S5521-S5525. DOI: 10.1179/1432891714Z.0000000001144  0.4
2015 Zhou X, Zhong Z, Zhang B, He R, Guan K, Wang Q, Matolak D. Experimental Characterization and Correlation Analysis of Indoor Channels at 15 GHz International Journal of Antennas and Propagation. 2015. DOI: 10.1155/2015/601835  0.64
2015 Jiang N, Zhou Z, Guan KY, Yu WB. Nomenclatural transfer of Chinese Pulsatilla to Anemone (Ranunculaceae) Nordic Journal of Botany. 33: 469-471. DOI: 10.1111/njb.00700  0.64
2015 Guan K, Ai B, Zhong Z, Lopez CF, Zhang L, Briso-Rodriguez C. Poster: Excess propagation loss for train-to-x communications in curved subway tunnels Ieee Vehicular Networking Conference, Vnc. 2015: 195-196. DOI: 10.1109/VNC.2014.7013344  0.64
2015 Ding J, Zhong Z, He R, Guan K, Rodriguez CB. Wideband channel measurements and analysis in High-Speed Railway environments 2015 1st Ursi Atlantic Radio Science Conference, Ursi At-Rasc 2015. DOI: 10.1109/URSI-AT-RASC.2015.7303002  0.64
2015 Guan K, Ai B, Zhong Z, López CF, Zhang L, Briso-Rodríguez C, Hrovat A, Zhang B, He R, Tang T. Measurements and Analysis of Large-Scale Fading Characteristics in Curved Subway Tunnels at 920 MHz, 2400 MHz, and 5705 MHz Ieee Transactions On Intelligent Transportation Systems. 16: 2393-2405. DOI: 10.1109/TITS.2015.2404851  0.64
2015 He R, Zhong Z, Ai B, Guan K. Reducing the Cost of High-Speed Railway Communications: From the Propagation Channel View Ieee Transactions On Intelligent Transportation Systems. 16: 2050-2060. DOI: 10.1109/TITS.2015.2390614  0.44
2015 Guan K, Tulino AM, Winzer PJ, Soljanin E. Secrecy capacities in space-division multiplexed fiber optic communication systems Ieee Transactions On Information Forensics and Security. 10: 1325-1335. DOI: 10.1109/TIFS.2015.2405897  0.6
2015 Chen B, Zhong Z, Ai B, Guan K, He R, Michelson DG. Channel characteristics in high-speed railway: A survey of channel propagation properties Ieee Vehicular Technology Magazine. 10: 67-78. DOI: 10.1109/MVT.2015.2411031  0.64
2015 Ai B, Guan K, Rupp M, Kurner T, Cheng X, Yin XF, Wang Q, Ma GY, Li Y, Xiong L, Ding JW. Future railway services-oriented mobile communications network Ieee Communications Magazine. 53: 78-85. DOI: 10.1109/MCOM.2015.7295467  0.64
2015 Xu JJ, Yao WG, Tian ZN, Wang L, Guan KM, Xu Y, Chen QD, Duan JA, Sun HB. High Curvature Concave-Convex Microlens Ieee Photonics Technology Letters. 27: 2465-2468. DOI: 10.1109/LPT.2015.2470195  0.36
2015 Lin S, Kong L, He L, Guan K, Ai B, Zhong Z, Briso-Rodriguez C. Finite-state Markov modeling for high-speed railway fading channels Ieee Antennas and Wireless Propagation Letters. 14: 954-957. DOI: 10.1109/Lawp.2015.2388701  0.44
2015 Chen JB, Chen TT, Guan KP, Ran X. Research on automatic assessment of ship berthing operation on marine simulator Ictis 2015 - 3rd International Conference On Transportation Information and Safety, Proceedings. 477-480. DOI: 10.1109/ICTIS.2015.7232106  0.4
2015 Guan K, Cho J, Winzer PJ, Tulino AM, Soljanin E. Enhanced physical layer security of MIMO-SDM systems through information scrambling European Conference On Optical Communication, Ecoc. 2015. DOI: 10.1109/ECOC.2015.7341892  0.6
2015 Liu Y, Ai B, Guan K, Chen B. Antenna array configurations for 3D MIMO system in high speed railway scenario Ieee Antennas and Propagation Society, Ap-S International Symposium (Digest). 2015: 719-720. DOI: 10.1109/APS.2015.7304746  0.64
2015 Zhang B, Zhong Z, He R, Guan K, Ding J, Briso-Rodriguez C. Empirical correlation property of multi-path for high-speed railways in composite propagation scenario Ieee Antennas and Propagation Society, Ap-S International Symposium (Digest). 2015: 91-92. DOI: 10.1109/APS.2015.7304431  0.64
2015 Guan K, Zhong Z, Ai B, Briso-Rodriguez C, Zhang L. Large scale fading characteristics in rail traffic scenarios Ieee Antennas and Propagation Society, Ap-S International Symposium (Digest). 2015: 83-84. DOI: 10.1109/APS.2015.7304427  0.64
2015 Wang Q, AI B, Guan K, Li Y, Zhong Z. Ray-based analysis of small-scale fading for indoor corridor scenarios at 15 GHz 2015 Asia-Pacific International Symposium On Electromagnetic Compatibility, Apemc 2015. 181-184. DOI: 10.1109/APEMC.2015.7175320  0.64
2015 Zhou X, Zhong Z, Bian X, Xiong L, Guan K, He R, Liu K, Wu J. Measurement uncertainty introduced by instruments in frequency domain channel measurement systems with a covariance-based analysis 2015 Asia-Pacific International Symposium On Electromagnetic Compatibility, Apemc 2015. 302-305. DOI: 10.1109/APEMC.2015.7175256  0.64
2015 Zhao B, Shao G, Fan B, Zhao W, Zhang S, Guan K, Zhang R. In situ synthesis of novel urchin-like ZnS/Ni3S2@Ni composite with a core-shell structure for efficient electromagnetic absorption Journal of Materials Chemistry C. 3: 10862-10869. DOI: 10.1039/C5Tc02063H  0.6
2015 Chen Y, Xu YY, Huang LY, Xu YH, Guan KS. Creep Behavior of Metal-to-Metal Contact Bolted Flanged Joint Procedia Engineering. 130: 214-220. DOI: 10.1016/J.Proeng.2015.12.211  0.52
2015 Zhang LZ, Liu Y, Sun JC, Ma K, Cai RL, Guan KS. Research on the Assembly Pattern of MMC Bolted Flange Joint Procedia Engineering. 130: 193-203. DOI: 10.1016/j.proeng.2015.12.188  0.52
2015 Kong B, Jia L, Su L, Guan K, Weng J, Zhang H. Effects of minor Si on microstructures and room temperature fracture toughness of niobium solid solution alloys Materials Science and Engineering A. 639: 114-121. DOI: 10.1016/j.msea.2015.04.096  0.44
2015 Song M, Gurao NP, Qin W, Szpunar JA, Guan KS. Deciphering deviation in mechanical properties of differently processed AISI 316L austenitic stainless steel using the small punch test Materials Science and Engineering A. 628: 116-123. DOI: 10.1016/J.Msea.2015.01.045  0.36
2015 Qin W, Guan K, Lei B, Liu Y, Peng C, Wu J. One-step coating and characterization of α-Al2O3 microfiltration membrane Journal of Membrane Science. 490: 160-168. DOI: 10.1016/j.memsci.2015.05.003  0.44
2015 Ren H, Zhang L, Su K, Zeng Q, Guan K, Cheng L. Thermodynamic study of the chemical vapor deposition in the SiCl3CH3-NH3-H2 system Chemical Physics Letters. 623: 29-36. DOI: 10.1016/j.cplett.2015.01.042  0.44
2015 Guan K. Geometrically convex solutions of a generalized gamma functional equation Aequationes Mathematicae. 89: 1003-1013. DOI: 10.1007/s00010-014-0292-4  0.48
2015 Guan K, Wei Z, Yin B. Soc prediction method of a new lithium battery based on ga-bp neural network Lecture Notes in Electrical Engineering. 355: 141-153. DOI: 10.1007/978-3-319-11104-9_17  0.32
2015 Chen Y, Guan KS, Ma K, Zhang LZ, Xu YY. Analysis on temperature distribution and heat loss of bolted flanged connections at high temperature Huadong Ligong Daxue Xuebao/Journal of East China University of Science and Technology. 41: 857-862.  0.52
2015 Gao G, Yu Z, Yan J, Li J, Shen S, Jia B, Guan K, Gao X, Kan Q. Lowering blood ammonia prevents hepatocyte injury and apoptosis International Journal of Clinical and Experimental Medicine. 8: 12347-12355.  0.44
2015 Zhang L, Fernandez JR, Rodriguez CB, Rodriguez C, Moreno J, Guan K. Broadband radio communications in subway stations and tunnels 2015 9th European Conference On Antennas and Propagation, Eucap 2015 0.64
2015 Guan K, Ai B, Zhong Z, López CF, Zhang L, Briso-Rodríguez C, Zhang B. Large-scale fading characterization in curved modern subway tunnels 2015 9th European Conference On Antennas and Propagation, Eucap 2015 0.64
2015 Qin YF, Feng XS, Guan KS. Determination of norton creep parameters by small punch creep test Huadong Ligong Daxue Xuebao/Journal of East China University of Science and Technology. 41: 569-574.  0.52
2014 Parmigiani A, Nourbakhsh A, Ding B, Wang W, Kim YC, Akopiants K, Guan KL, Karin M, Budanov AV. Sestrins inhibit mTORC1 kinase activation through the GATOR complex. Cell Reports. 9: 1281-91. PMID 25457612 DOI: 10.1016/J.Celrep.2014.10.019  1
2014 Zhao B, Guan KL. Hippo pathway key to ploidy checkpoint. Cell. 158: 695-6. PMID 25126776 DOI: 10.1016/J.Cell.2014.07.041  1
2014 Gao Y, Zhang W, Han X, Li F, Wang X, Wang R, Fang Z, Tong X, Yao S, Li F, Feng Y, Sun Y, Hou Y, Yang Z, Guan K, et al. YAP inhibits squamous transdifferentiation of Lkb1-deficient lung adenocarcinoma through ZEB2-dependent DNp63 repression. Nature Communications. 5: 4629. PMID 25115923 DOI: 10.1038/Ncomms5629  0.76
2014 Yang H, Lin H, Xu H, Zhang L, Cheng L, Wen B, Shou J, Guan K, Xiong Y, Ye D. TET-catalyzed 5-methylcytosine hydroxylation is dynamically regulated by metabolites. Cell Research. 24: 1017-20. PMID 24971736 DOI: 10.1038/Cr.2014.81  0.8
2014 Yu FX, Luo J, Mo JS, Liu G, Kim YC, Meng Z, Zhao L, Peyman G, Ouyang H, Jiang W, Zhao J, Chen X, Zhang L, Wang CY, Bastian BC, ... Guan KL, et al. Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP. Cancer Cell. 25: 822-30. PMID 24882516 DOI: 10.1016/J.Ccr.2014.04.017  1
2014 Wang P, Zhou Z, Hu A, Ponte de Albuquerque C, Zhou Y, Hong L, Sierecki E, Ajiro M, Kruhlak M, Harris C, Guan KL, Zheng ZM, Newton AC, Sun P, Zhou H, et al. Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt. Molecular Cell. 54: 378-91. PMID 24703948 DOI: 10.1016/J.Molcel.2014.03.007  1
2014 Yu FX, Guan KL. Transcription and processing: multilayer controls of RNA biogenesis by the Hippo pathway. The Embo Journal. 33: 942-4. PMID 24639555 DOI: 10.1002/Embj.201488329  1
2014 Russell RC, Yuan HX, Guan KL. Autophagy regulation by nutrient signaling. Cell Research. 24: 42-57. PMID 24343578 DOI: 10.1038/Cr.2013.166  0.72
2013 Li J, Chen X, Ding X, Cheng Y, Zhao B, Lai ZC, Al Hezaimi K, Hakem R, Guan KL, Wang CY. LATS2 suppresses oncogenic Wnt signaling by disrupting β-catenin/BCL9 interaction. Cell Reports. 5: 1650-63. PMID 24360964 DOI: 10.1016/J.Celrep.2013.11.037  1
2013 Yang H, Xiong Y, Guan K. Metabolic alteration in tumorigenesis. Science China. Life Sciences. 56: 1067-75. PMID 24114443 DOI: 10.1007/S11427-013-4549-2  0.8
2013 Dai X, She P, Chi F, Feng Y, Liu H, Jin D, Zhao Y, Guo X, Jiang D, Guan KL, Zhong TP, Zhao B. Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration, and angiogenesis. The Journal of Biological Chemistry. 288: 34041-51. PMID 24106267 DOI: 10.1074/Jbc.M113.518019  0.8
2013 Yuan HX, Russell RC, Guan KL. Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy. Autophagy. 9: 1983-95. PMID 24013218 DOI: 10.4161/Auto.26058  0.72
2013 Kim J, Guan KL. AMPK connects energy stress to PIK3C3/VPS34 regulation. Autophagy. 9: 1110-1. PMID 23669030 DOI: 10.4161/Auto.24877  1
2013 Yu FX, Guan KL. The Hippo pathway: regulators and regulations. Genes & Development. 27: 355-71. PMID 23431053 DOI: 10.1101/Gad.210773.112  1
2013 Yuan HX, Xiong Y, Guan KL. Nutrient sensing, metabolism, and cell growth control. Molecular Cell. 49: 379-87. PMID 23395268 DOI: 10.1016/J.Molcel.2013.01.019  0.8
2013 Li L, Guan KL. Microtubule-associated protein/microtubule affinity-regulating kinase 4 (MARK4) is a negative regulator of the mammalian target of rapamycin complex 1 (mTORC1). The Journal of Biological Chemistry. 288: 703-8. PMID 23184942 DOI: 10.1074/Jbc.C112.396903  1
2013 Kim J, Russell R, Yuan H, Guan K. Abstract SY08-01: AMPK and mTOR in nutrient signaling, metabolism, and autophagy regulation. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy08-01  1
2013 Wang Y, Zhou L, Zhao Y, Wang S, Yang Y, Ye D, Xiong Y, Guan K. Abstract 5177: SIRT2 deacetylates and activates glucose-6-phosphate dehydrogenase (G6PD) to protect cells against oxidative stress. Cancer Research. 73: 5177-5177. DOI: 10.1158/1538-7445.Am2013-5177  0.8
2012 Tumaneng K, Schlegelmilch K, Russell RC, Yimlamai D, Basnet H, Mahadevan N, Fitamant J, Bardeesy N, Camargo FD, Guan KL. YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29. Nature Cell Biology. 14: 1322-9. PMID 23143395 DOI: 10.1038/Ncb2615  0.48
2012 Yu FX, Mo JS, Guan KL. Upstream regulators of the Hippo pathway. Cell Cycle (Georgetown, Tex.). 11: 4097-8. PMID 23075495 DOI: 10.4161/Cc.22322  0.64
2012 Mo JS, Yu FX, Gong R, Brown JH, Guan KL. Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs). Genes & Development. 26: 2138-43. PMID 22972936 DOI: 10.1101/Gad.197582.112  1
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Guan KL, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.84
2012 Magee JA, Ikenoue T, Nakada D, Lee JY, Guan KL, Morrison SJ. Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression. Cell Stem Cell. 11: 415-28. PMID 22958933 DOI: 10.1016/J.Stem.2012.05.026  1
2012 Tang F, Wu Q, Ikenoue T, Guan KL, Liu Y, Zheng P. A critical role for Rictor in T lymphopoiesis. Journal of Immunology (Baltimore, Md. : 1950). 189: 1850-7. PMID 22815285 DOI: 10.4049/Jimmunol.1201057  0.6
2012 Purohit AA, Li W, Qu C, Dwyer T, Shao Q, Guan KL, Liu G. Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse. The Journal of Biological Chemistry. 287: 27126-38. PMID 22685302 DOI: 10.1074/Jbc.M112.340174  1
2012 Hong W, Guan KL. The YAP and TAZ transcription co-activators: key downstream effectors of the mammalian Hippo pathway. Seminars in Cell & Developmental Biology. 23: 785-93. PMID 22659496 DOI: 10.1016/J.Semcdb.2012.05.004  0.36
2012 Tumaneng K, Russell RC, Guan KL. Organ size control by Hippo and TOR pathways. Current Biology : Cb. 22: R368-79. PMID 22575479 DOI: 10.1016/J.Cub.2012.03.003  0.48
2012 Valbuena N, Guan KL, Moreno S. The Vam6 and Gtr1-Gtr2 pathway activates TORC1 in response to amino acids in fission yeast. Journal of Cell Science. 125: 1920-8. PMID 22344254 DOI: 10.1242/Jcs.094219  1
2012 Wang P, Dong Q, Zhang C, Kuan P, Liu Y, Jeck WR, Andersen JB, Auman JT, Hoskins JM, Kim JW, Cibulskis K, Getz G, Hunt HV, Thorgeirsson SS, Roberts LR, ... ... Guan K, et al. Abstract 1058: Mutations in isocitrate dehydrogenase 1 and 2 are associated with DNA hypermethylation in intrahepatic cholangiocarcinomas Cancer Research. 72: 1058-1058. DOI: 10.1158/1538-7445.Am2012-1058  0.8
2011 Lu MK, Gong XG, Guan KL. mTOR in podocyte function: is rapamycin good for diabetic nephropathy? Cell Cycle (Georgetown, Tex.). 10: 3415-6. PMID 22067710 DOI: 10.4161/Cc.10.20.17686  0.52
2011 Tan ES, Tang MB, Guan KY, Lee JS, Cerroni L, Tan SH. A case of myeloid sarcoma with unusually extensive and rapidly progressive skin manifestations. Annals of the Academy of Medicine, Singapore. 40: 424-6. PMID 22065039  0.32
2011 Gong R, Li L, Liu Y, Wang P, Yang H, Wang L, Cheng J, Guan KL, Xu Y. Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation. Genes & Development. 25: 1668-73. PMID 21816923 DOI: 10.1101/Gad.16968011  0.8
2011 Zhao B, Tumaneng K, Guan KL. The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal. Nature Cell Biology. 13: 877-83. PMID 21808241 DOI: 10.1038/Ncb2303  0.68
2011 Yoshida S, Hong S, Suzuki T, Nada S, Mannan AM, Wang J, Okada M, Guan KL, Inoki K. Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway. The Journal of Biological Chemistry. 286: 32651-60. PMID 21784859 DOI: 10.1074/Jbc.M111.238014  0.56
2011 Wu Q, Liu Y, Chen C, Ikenoue T, Qiao Y, Li CS, Li W, Guan KL, Liu Y, Zheng P. The tuberous sclerosis complex-mammalian target of rapamycin pathway maintains the quiescence and survival of naive T cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 1106-12. PMID 21709159 DOI: 10.4049/Jimmunol.1003968  0.84
2011 Kim J, Guan KL. Amino acid signaling in TOR activation. Annual Review of Biochemistry. 80: 1001-32. PMID 21548787 DOI: 10.1146/Annurev-Biochem-062209-094414  1
2011 Egan D, Kim J, Shaw RJ, Guan KL. The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR. Autophagy. 7: 643-4. PMID 21460621 DOI: 10.4161/Auto.7.6.15123  1
2011 Kim J, Guan KL. Regulation of the autophagy initiating kinase ULK1 by nutrients: roles of mTORC1 and AMPK. Cell Cycle (Georgetown, Tex.). 10: 1337-8. PMID 21403467 DOI: 10.4161/Cc.10.9.15291  1
2011 Xie X, Guan KL. The ribosome and TORC2: collaborators for cell growth. Cell. 144: 640-2. PMID 21376227 DOI: 10.1016/J.Cell.2011.02.029  1
2011 Zheng M, Wang YH, Wu XN, Wu SQ, Lu BJ, Dong MQ, Zhang H, Sun P, Lin SC, Guan KL, Han J. Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1. Nature Cell Biology. 13: 263-72. PMID 21336308 DOI: 10.1038/Ncb2168  1
2011 Kim J, Kundu M, Viollet B, Guan KL. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nature Cell Biology. 13: 132-41. PMID 21258367 DOI: 10.1038/Ncb2152  1
2011 Hallows WC, Yu W, Smith BC, Devries MK, Devires MK, Ellinger JJ, Someya S, Shortreed MR, Prolla T, Markley JL, Smith LM, Zhao S, Guan KL, Denu JM. Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Molecular Cell. 41: 139-49. PMID 21255725 DOI: 10.1016/J.Molcel.2011.01.002  1
2011 Zhao B, Li L, Lu Q, Wang LH, Liu CY, Lei Q, Guan KL. Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. Genes & Development. 25: 51-63. PMID 21205866 DOI: 10.1101/Gad.2000111  0.68
2010 Zhao B, Li L, Guan KL. Hippo signaling at a glance. Journal of Cell Science. 123: 4001-6. PMID 21084559 DOI: 10.1242/Jcs.069070  0.68
2010 Zhao S, Guan KL. IDH1 mutant structures reveal a mechanism of dominant inhibition. Cell Research. 20: 1279-81. PMID 21079649 DOI: 10.1038/Cr.2010.160  1
2010 Wang C, Yoo Y, Fan H, Kim E, Guan KL, Guan JL. Regulation of Integrin β 1 recycling to lipid rafts by Rab1a to promote cell migration. The Journal of Biological Chemistry. 285: 29398-405. PMID 20639577 DOI: 10.1074/Jbc.M110.141440  0.8
2010 Zhao B, Li L, Lei Q, Guan KL. The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. Genes & Development. 24: 862-74. PMID 20439427 DOI: 10.1101/Gad.1909210  0.68
2010 Wang Q, Zhang Y, Yang C, Xiong H, Lin Y, Yao J, Li H, Xie L, Zhao W, Yao Y, Ning ZB, Zeng R, Xiong Y, Guan KL, Zhao S, et al. Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux. Science (New York, N.Y.). 327: 1004-7. PMID 20167787 DOI: 10.1126/Science.1179687  0.8
2010 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, ... ... Guan KL, et al. Regulation of cellular metabolism by protein lysine acetylation. Science (New York, N.Y.). 327: 1000-4. PMID 20167786 DOI: 10.1126/Science.1179689  1
2010 Li Z, Zhao B, Wang P, Chen F, Dong Z, Yang H, Guan KL, Xu Y. Structural insights into the YAP and TEAD complex. Genes & Development. 24: 235-40. PMID 20123905 DOI: 10.1101/Gad.1865810  0.8
2010 Zhao B, Li L, Tumaneng K, Wang CY, Guan KL. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes & Development. 24: 72-85. PMID 20048001 DOI: 10.1101/Gad.1843810  0.8
2010 Alexander A, Cai S, Kim J, Nanez A, Sahin M, MacLean KH, Inoki K, Guan K, Shen J, Person MD, Kusewitt D, Mills GB, Kastan MB, Walker CL. Abstract 4831: ATM signals to TSC2 in the cytoplasm to regulate mTORC1 and autophagy in response to ROS Cancer Research. 70: 4831-4831. DOI: 10.1158/1538-7445.Am10-4831  1
2009 Zhao B, Lei Q, Guan KL. Mst out and HCC in. Cancer Cell. 16: 363-4. PMID 19878866 DOI: 10.1016/J.Ccr.2009.10.008  0.68
2009 Li L, Guan KL. Amino Acid Signaling to TOR Activation: Vam6 Functioning as a Gtr1 GEF Molecular Cell. 35: 543-545. PMID 19748348 DOI: 10.1016/J.Molcel.2009.08.010  1
2009 Chang J, Wang Z, Tang E, Fan Z, McCauley L, Franceschi R, Guan K, Krebsbach PH, Wang CY. Inhibition of osteoblastic bone formation by nuclear factor-kappaB. Nature Medicine. 15: 682-9. PMID 19448637 DOI: 10.1038/Nm.1954  1
2009 Zhao S, Lin Y, Xu W, Jiang W, Zha Z, Wang P, Yu W, Li Z, Gong L, Peng Y, Ding J, Lei Q, Guan KL, Xiong Y. Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science (New York, N.Y.). 324: 261-5. PMID 19359588 DOI: 10.1126/Science.1170944  0.8
2009 Yu W, Lin Y, Yao J, Huang W, Lei Q, Xiong Y, Zhao S, Guan KL. Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals. The Journal of Biological Chemistry. 284: 13669-75. PMID 19318352 DOI: 10.1074/Jbc.M901921200  0.8
2009 Zhao B, Lei QY, Guan KL. Harness the power: new insights into the inhibition of YAP/Yorkie. Developmental Cell. 16: 321-2. PMID 19289076 DOI: 10.1016/J.Devcel.2009.02.015  0.68
2009 Kim E, Guan KL. RAG GTPases in nutrient-mediated TOR signaling pathway. Cell Cycle (Georgetown, Tex.). 8: 1014-8. PMID 19270521 DOI: 10.4161/Cc.8.7.8124  1
2009 Liu G, Li W, Wang L, Kar A, Guan KL, Rao Y, Wu JY. DSCAM functions as a netrin receptor in commissural axon pathfinding. Proceedings of the National Academy of Sciences of the United States of America. 106: 2951-6. PMID 19196994 DOI: 10.1073/Pnas.0811083106  1
2009 Zhao B, Kim J, Ye X, Lai ZC, Guan KL. Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein. Cancer Research. 69: 1089-98. PMID 19141641 DOI: 10.1158/0008-5472.Can-08-2997  1
2008 Zhao B, Lei QY, Guan KL. The Hippo-YAP pathway: new connections between regulation of organ size and cancer. Current Opinion in Cell Biology. 20: 638-46. PMID 18955139 DOI: 10.1016/J.Ceb.2008.10.001  0.68
2008 Chen C, Liu Y, Liu R, Ikenoue T, Guan KL, Liu Y, Zheng P. TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. The Journal of Experimental Medicine. 205: 2397-408. PMID 18809716 DOI: 10.1084/Jem.20081297  0.6
2008 Mardanpour P, Guan K, Nolte J, Lee JH, Hasenfuss G, Engel W, Nayernia K. Potency of germ cells and its relevance for regenerative medicine. Journal of Anatomy. 213: 26-9. PMID 18565110 DOI: 10.1111/j.1469-7580.2008.00930.x  0.32
2008 Zhao S, Guan KL. Substrate selectivity APPLies to Akt. Cell. 133: 399-400. PMID 18455980 DOI: 10.1016/J.Cell.2008.04.015  1
2007 Lee CH, Inoki K, Karbowniczek M, Petroulakis E, Sonenberg N, Henske EP, Guan KL. Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53. The Embo Journal. 26: 4812-23. PMID 17962806 DOI: 10.1038/Sj.Emboj.7601900  1
2007 Yang Q, Guan KL. Expanding mTOR signaling Cell Research. 17: 666-681. PMID 17680028 DOI: 10.1038/Cr.2007.64  1
2007 Lee CH, Inoki K, Guan KL. mTOR pathway as a target in tissue hypertrophy. Annual Review of Pharmacology and Toxicology. 47: 443-67. PMID 16968213 DOI: 10.1146/annurev.pharmtox.47.120505.105359  0.56
2006 Wan M, Wu X, Guan KL, Han M, Zhuang Y, Xu T. Muscle atrophy in transgenic mice expressing a human TSC1 transgene. Febs Letters. 580: 5621-7. PMID 16996505 DOI: 10.1016/J.Febslet.2006.09.008  1
2006 Guan K, Nayernia K, Maier LS, Wagner S, Dressel R, Lee JH, Nolte J, Wolf F, Li M, Engel W, Hasenfuss G. Pluripotency of spermatogonial stem cells from adult mouse testis. Nature. 440: 1199-203. PMID 16565704 DOI: 10.1038/nature04697  0.32
2006 Li W, Aurandt J, Jürgensen C, Jürgense C, Rao Y, Guan KL. FAK and Src kinases are required for netrin-induced tyrosine phosphorylation of UNC5. Journal of Cell Science. 119: 47-55. PMID 16371650 DOI: 10.1242/Jcs.02697  0.84
2005 Kruger RP, Aurandt J, Guan KL. Semaphorins command cells to move. Nature Reviews. Molecular Cell Biology. 6: 789-800. PMID 16314868 DOI: 10.1038/Nrm1740  0.68
2005 Lee J, Li W, Guan KL. SRC-1 mediates UNC-5 signaling in Caenorhabditis elegans. Molecular and Cellular Biology. 25: 6485-95. PMID 16024786 DOI: 10.1128/Mcb.25.15.6485-6495.2005  0.84
2005 Yu Y, Li S, Xu X, Li Y, Guan K, Arnold E, Ding J. Structural basis for the unique biological function of small GTPase RHEB. The Journal of Biological Chemistry. 280: 17093-100. PMID 15728574 DOI: 10.1074/Jbc.M501253200  0.72
2005 Wolf MT, Lee J, Panther F, Otto EA, Guan KL, Hildebrandt F. Expression and phenotype analysis of the nephrocystin-1 and nephrocystin-4 homologs in Caenorhabditis elegans. Journal of the American Society of Nephrology : Jasn. 16: 676-87. PMID 15659564 DOI: 10.1681/Asn.2003121025  0.84
2005 Inoki K, Corradetti MN, Guan KL. Dysregulation of the TSC-mTOR pathway in human disease. Nature Genetics. 37: 19-24. PMID 15624019 DOI: 10.1038/Ng1494  0.56
2005 Zhou Q, Rammohan KW, Lin S, Robinson N, Li O, Liu X, Bai XF, Yin L, Scarberry B, Du P, You M, Guan K, Zheng P, Liu Y. Erratum: CD24 is a genetic modifier for risk and progression of multiple sclerosis (Proceedings of the National Academy of Sciences of the United States of America (December 9, 2003) 100, 25 (15041-15046)) Proceedings of the National Academy of Sciences of the United States of America. 102. DOI: 10.1073/Pnas.0503722102  0.6
2004 Kruger RP, Lee J, Li W, Guan KL. Mapping netrin receptor binding reveals domains of Unc5 regulating its tyrosine phosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10826-34. PMID 15574733 DOI: 10.1523/Jneurosci.3715-04.2004  0.84
2004 Li W, Lee J, Vikis HG, Lee SH, Liu G, Aurandt J, Shen TL, Fearon ER, Guan JL, Han M, Rao Y, Hong K, Guan KL. Activation of FAK and Src are receptor-proximal events required for netrin signaling. Nature Neuroscience. 7: 1213-21. PMID 15494734 DOI: 10.1038/Nn1329  1
2004 Basile JR, Barac A, Zhu T, Guan KL, Gutkind JS. Class IV semaphorins promote angiogenesis by stimulating Rho-initiated pathways through plexin-B. Cancer Research. 64: 5212-24. PMID 15289326 DOI: 10.1158/0008-5472.Can-04-0126  0.32
2004 Li W, Zhu T, Guan K. Transformation Potential of Ras Isoforms Correlates with Activation of Phosphatidylinositol 3-Kinase but Not ERK Journal of Biological Chemistry. 279: 37398-37406. PMID 15210703 DOI: 10.1074/Jbc.M405730200  0.84
2004 Vikis HG, Guan KL. Glutathione-S-transferase-fusion based assays for studying protein-protein interactions Methods in Molecular Biology (Clifton, N.J.). 261: 175-186. PMID 15064458 DOI: 10.1385/1-59259-762-9:175  1
2004 Wang M, Devereux TR, Vikis HG, McCulloch SD, Holliday W, Anna C, Wang Y, Bebenek K, Kunkel TA, Guan K, You M. Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia. Cancer Research. 64: 1924-31. PMID 15026325 DOI: 10.1158/0008-5472.Can-03-3080  1
2004 Xie S, Wang Q, Ruan Q, Liu T, Jhanwar-Uniyal M, Guan K, Dai W. MEK1-induced Golgi dynamics during cell cycle progression is partly mediated by Polo-like kinase-3. Oncogene. 23: 3822-9. PMID 15021912 DOI: 10.1038/Sj.Onc.1207479  0.48
2004 Ruan Q, Wang Q, Xie S, Fang Y, Darzynkiewicz Z, Guan K, Jhanwar-Uniyal M, Dai W. Polo-like kinase 3 is Golgi localized and involved in regulating Golgi fragmentation during the cell cycle. Experimental Cell Research. 294: 51-9. PMID 14980500 DOI: 10.1016/J.Yexcr.2003.10.022  0.48
2004 Yang F, Yamashita J, Tang E, Wang HL, Guan K, Wang CY. The zinc finger mutation C417R of I-kappa B kinase gamma impairs lipopolysaccharide- and TNF-mediated NF-kappa B activation through inhibiting phosphorylation of the I-kappa B kinase beta activation loop. Journal of Immunology (Baltimore, Md. : 1950). 172: 2446-52. PMID 14764716 DOI: 10.4049/Jimmunol.172.4.2446  0.8
2003 Guan KL, Rao Y. Signalling mechanisms mediating neuronal responses to guidance cues. Nature Reviews. Neuroscience. 4: 941-56. PMID 14682358 DOI: 10.1038/Nrn1254  0.36
2003 Zhou Q, Rammohan K, Lin S, Robinson N, Li O, Liu X, Bai XF, Yin L, Scarberry B, Du P, You M, Guan K, Zheng P, Liu Y. CD24 is a genetic modifier for risk and progression of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 100: 15041-6. PMID 14657362 DOI: 10.1073/Pnas.2533866100  0.6
2003 Zhang Z, Futamura M, Vikis HG, Wang M, Li J, Wang Y, Guan KL, You M. Positional cloning of the major quantitative trait locus underlying lung tumor susceptibility in mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 12642-7. PMID 14583591 DOI: 10.1073/Pnas.2133947100  0.8
2003 Tang ED, Inohara N, Wang CY, Nuñez G, Guan KL. Roles for homotypic interactions and transautophosphorylation in IkappaB kinase beta IKKbeta) activation [corrected]. The Journal of Biological Chemistry. 278: 38566-70. PMID 12890679 DOI: 10.1074/Jbc.M304374200  0.8
2003 Tang ED, Wang CY, Xiong Y, Guan KL. A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha. The Journal of Biological Chemistry. 278: 37297-305. PMID 12867425 DOI: 10.1074/Jbc.M303389200  0.8
2003 Hurley JH, Zhang S, Bye LS, Marshall MS, DePaoli-Roach AA, Guan K, Fox AP, Yu L. Insulin signaling inhibits the 5-HT2C receptor in choroid plexus via MAP kinase. Bmc Neuroscience. 4: 10. PMID 12795815 DOI: 10.1186/1471-2202-4-10  1
2003 Yang F, Tang E, Guan K, Wang CY. IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide. Journal of Immunology (Baltimore, Md. : 1950). 170: 5630-5. PMID 12759443 DOI: 10.4049/Jimmunol.170.11.5630  0.8
2002 Vikis H, Guan KL. Regulation of the Ras-MAPK pathway at the level of Ras and Raf Genetic Engineering. 24: 49-66. PMID 12416300 DOI: 10.1007/978-1-4615-0721-5_3  1
2002 Aurandt J, Vikis HG, Gutkind JS, Ahn N, Guan KL. The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG Proceedings of the National Academy of Sciences of the United States of America. 99: 12085-12090. PMID 12196628 DOI: 10.1073/Pnas.142433199  1
2002 Vikis HG, Stewart S, Guan K. SmgGDS displays differential binding and exchange activity towards different Ras isoforms. Oncogene. 21: 2425-2432. PMID 11948427 DOI: 10.1038/Sj.Onc.1205306  0.52
2001 Zhan XL, Wishart MJ, Guan KL. Nonreceptor tyrosine phosphatases in cellular signaling: regulation of mitogen-activated protein kinases. Chemical Reviews. 101: 2477-96. PMID 11749384 DOI: 10.1021/cr000245u  0.92
2001 Chen S, Guttridge DC, Tang E, Shi S, Guan K, Wang C. Suppression of Tumor Necrosis Factor-mediated Apoptosis by Nuclear Factor κB-independent Bone Morphogenetic Protein/Smad Signaling Journal of Biological Chemistry. 276: 39259-39263. PMID 11500509 DOI: 10.1074/Jbc.M105335200  0.8
2001 Chong H, Lee J, Guan KL. Positive and negative regulation of Raf kinase activity and function by phosphorylation. The Embo Journal. 20: 3716-27. PMID 11447113 DOI: 10.1093/Emboj/20.14.3716  1
2001 Zhang BH, Guan KL. Regulation of the Raf kinase by phosphorylation Experimental Lung Research. 27: 269-295. PMID 11293329 DOI: 10.1080/019021401300054046  1
2001 Tan M, Bian J, Guan K, Sun Y. p53CP is p51/p63, the third member of the p53 gene family: partial purification and characterization Carcinogenesis. 22: 295-300. PMID 11181451 DOI: 10.1093/Carcin/22.2.295  0.76
2001 Li Y, Li M, Xing G, Hu Z, Wang Q, Dong C, Wei H, Fan G, Chen J, Yang X, Zhao S, Chen H, Guan K, Wu C, Zhang C, et al. Stimulation of the mitogen-activated protein kinase cascade and tyrosine phosphorylation of the epidermal growth factor receptor by hepatopoietin. The Journal of Biological Chemistry. 275: 37443-7. PMID 10982794 DOI: 10.1074/Jbc.M004373200  0.36
2000 Zhang BH, Guan KL. Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601 Embo Journal. 19: 5429-5439. PMID 11032810 DOI: 10.1093/Emboj/19.20.5429  1
2000 Simon AR, Vikis HG, Stewart S, Fanburg BL, Cochran BH, Guan KL. Regulation of STAT3 by direct binding to the Rac1 GTPase. Science (New York, N.Y.). 290: 144-7. PMID 11021801 DOI: 10.1126/Science.290.5489.144  1
2000 Stewart S, Guan KL. The dominant negative Ras mutant, N17Ras, can inhibit signaling independently of blocking ras activation Journal of Biological Chemistry. 275: 8854-8862. PMID 10722731 DOI: 10.1074/Jbc.275.12.8854  1
2000 Zhan XL, Hong Y, Zhu T, Mitchell AP, Deschenes RJ, Guan KL. Essential functions of protein tyrosine phosphatases PTP2 and PTP3 and RIM11 tyrosine phosphorylation in Saccharomyces cerevisiae meiosis and sporulation. Molecular Biology of the Cell. 11: 663-76. PMID 10679022 DOI: 10.1091/Mbc.11.2.663  1
2000 Tan M, Wang Y, Guan K, Sun Y. PTGF-beta, a type beta transforming growth factor (TGF-beta) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-beta signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 97: 109-14. PMID 10618379 DOI: 10.1073/Pnas.97.1.109  0.8
2000 Li W, Han M, Guan K. The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf Genes & Development. 14: 895-900. DOI: 10.1101/Gad.14.8.895  0.84
1999 Zhan XL, Guan KL. A specific protein-protein interaction accounts for the in vivo substrate selectivity of Ptp3 towards the Fus3 MAP kinase. Genes & Development. 13: 2811-27. PMID 10557209 DOI: 10.1101/Gad.13.21.2811  1
1999 Guan KL, Han M. A G-protein signaling network mediated by an RGS protein Genes and Development. 13: 1763-1767. PMID 10421628 DOI: 10.1101/Gad.13.14.1763  1
1999 Stewart S, Sundaram M, Zhang Y, Lee J, Han M, Guan KL. Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization. Molecular and Cellular Biology. 19: 5523-34. PMID 10409742 DOI: 10.1128/Mcb.19.8.5523  0.84
1999 Tan M, Li S, Swaroop M, Guan K, Oberley LW, Sun Y. Transcriptional activation of the human glutathione peroxidase promoter by p53. The Journal of Biological Chemistry. 274: 12061-6. PMID 10207030 DOI: 10.1074/Jbc.274.17.12061  1
1999 Tan M, Heizmann CW, Guan K, Schafer BW, Sun Y. Transcriptional activation of the human S100A2 promoter by wild-type p53. Febs Letters. 445: 265-268. PMID 10094469 DOI: 10.1016/S0014-5793(99)00135-0  0.76
1998 Hodge C, Liao J, Stofega M, Guan K, Carter-Su C, Schwartz J. Growth hormone stimulates phosphorylation and activation of Elk-1 and expression of c-fos, egr-1, and junB through activation of extracellular signal-regulated kinases 1 and 2 Journal of Biological Chemistry. 273: 31327-31336. PMID 9813041 DOI: 10.1074/Jbc.273.47.31327  1
1998 Goldman D, Sapru MK, Stewart S, Plotkin J, Libermann TA, Wasylyk B, Guan K. Cloning and characterization of GETS-1, a goldfish Ets family member that functions as a transcriptional repressor in muscle Biochemical Journal. 335: 267-275. PMID 9761723 DOI: 10.1042/Bj3350267  1
1997 Zhan XL, Deschenes RJ, Guan KL. Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae. Genes & Development. 11: 1690-702. PMID 9224718 DOI: 10.1101/Gad.11.13.1690  1
1997 Gupta AK, Lee YJ, Galoforo SS, Berns CM, Martinez AA, Corry PM, Wu X, Guan K. Differential effect of glucose deprivation on MAPK activation in drug sensitive human breast carcinoma MCF-7 and multidrug resistant MCF-7/ADR cells Molecular and Cellular Biochemistry. 170: 23-30. PMID 9144315 DOI: 10.1023/A:1006890316102  0.64
1996 Butch ER, Guan KL. Characterization of ERK1 activation site mutants and the effect on recognition by MEK1 and MEK2 Journal of Biological Chemistry. 271: 4230-4235. PMID 8626767 DOI: 10.1074/Jbc.271.8.4230  1
1996 Wu X, Noh SJ, Zhou G, Dixon JE, Guan KL. Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated Hela cells. The Journal of Biological Chemistry. 271: 3265-71. PMID 8621729 DOI: 10.1074/Jbc.271.6.3265  0.64
1996 Sugimoto T, Haneda M, Togawa M, Isono M, Shikano T, Araki S, Nakagawa T, Kashiwagi A, Guan KL, Kikkawa R. Atrial natriuretic peptide induces the expression of MKP-1, a mitogen-activated protein kinase phosphatase, in glomerular mesangial cells. The Journal of Biological Chemistry. 271: 544-7. PMID 8550616 DOI: 10.1074/Jbc.271.1.544  1
1995 Pang L, Zheng CF, Guan KL, Saltiel AR. Nerve growth factor stimulates a novel protein kinase in PC-12 cells that phosphorylates and activates mitogen-activated protein kinase kinase (MEK) Biochemical Journal. 307: 513-519. PMID 7733891 DOI: 10.1042/Bj3070513  1
1995 Wang QM, Guan KL, Roach PJ, DePaoli-Roach AA. Phosphorylation and activation of the ATP-Mg-dependent protein phosphatase by the mitogen-activated protein kinase Journal of Biological Chemistry. 270: 18352-18358. PMID 7629158 DOI: 10.1074/Jbc.270.31.18352  1
1995 Guan KL, Butch E. Isolation and characterization of a novel dual specific phosphatase, HVH2, which selectively dephosphorylates the mitogen-activated protein kinase Journal of Biological Chemistry. 270: 7197-7203. PMID 7535768 DOI: 10.1074/Jbc.270.13.7197  1
1994 Frost JA, Alberts AS, Sontag E, Guan K, Mumby MC, Feramisco JR. Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity. Molecular and Cellular Biology. 14: 6244-52. PMID 8065356 DOI: 10.1128/Mcb.14.9.6244  1
1993 Guan KL, Dixon JE. Bacterial and viral protein tyrosine phosphatases. Seminars in Cell Biology. 4: 389-96. PMID 8305677 DOI: 10.1006/Scel.1993.1046  1
1993 Guan K, Farh L, Marshall TK, Deschenes RJ. Normal mitochondrial structure and genome maintenance in yeast requires the dynamin-like product of the MGM1 gene Current Genetics. 24: 141-148. PMID 7916673 DOI: 10.1007/Bf00324678  1
1993 Guan K, Hakes DJ, Wang Y, Park HD, Cooper TG, Dixon JE. A yeast protein phosphatase related to the vaccinia virus VH1 phosphatase is induced by nitrogen starvation. Proceedings of the National Academy of Sciences of the United States of America. 89: 12175-9. PMID 1334559 DOI: 10.1073/Pnas.89.24.12175  0.32
1991 Ni L, Guan K, Zalkin H, Dixon JE. De novo purine nucleotide biosynthesis: cloning, sequencing and expression of a chicken PurH cDNA encoding 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase-IMP cyclohydrolase Gene. 106: 197-205. PMID 1937050 DOI: 10.1016/0378-1119(91)90199-L  1
1991 Guan KL, Dixon JE. Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Analytical Biochemistry. 192: 262-7. PMID 1852137 DOI: 10.1016/0003-2697(91)90534-Z  1
1991 Guan KL, Broyles SS, Dixon JE. A Tyr/Ser protein phosphatase encoded by vaccinia virus. Nature. 350: 359-62. PMID 1848923 DOI: 10.1038/350359A0  1
1991 Clemens JC, Guan K, Bliska JB, Falkow S, Dixon JE. Microbial pathogenesis and tyrosine dephosphorylation: surprising 'bedfellows'. Molecular Microbiology. 5: 2617-20. PMID 1723471 DOI: 10.1111/J.1365-2958.1991.Tb01970.X  1
1990 Guan KL, Dixon JE. Protein tyrosine phosphatase activity of an essential virulence determinant in Yersinia. Science (New York, N.Y.). 249: 553-6. PMID 2166336 DOI: 10.1126/Science.2166336  1
1990 Guan KL, Haun RS, Watson SJ, Geahlen RL, Dixon JE. Cloning and expression of a protein-tyrosine-phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 87: 1501-5. PMID 2154749 DOI: 10.1073/Pnas.87.4.1501  0.36
1990 Guan K, Weiner H. Sequence of the precursor of bovine liver mitochondrial aldehyde dehydrogenase as determined from its cDNA, its gene, and its functionality Archives of Biochemistry and Biophysics. 277: 351-360. PMID 1689984 DOI: 10.1016/0003-9861(90)90590-U  1
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