| Year |
Citation |
Score |
| 2023 |
Lee TH, Checco JW, Malcolm T, Eller CH, Raines RT, Gellman SH, Lee EF, Fairlie WD, Aguilar MI. Differential membrane binding of α/β-peptide foldamers: implications for cellular delivery and mitochondrial targeting. Australian Journal of Chemistry. 76: 482-492. PMID 37780415 DOI: 10.1071/ch23063 |
0.764 |
|
| 2023 |
Gibadullin R, Kim TW, Tran LM, Gellman SH. Hormone Analogues with Unique Signaling Profiles from Replacement of α-Residue Triads with β/γ Diads. Journal of the American Chemical Society. PMID 37697685 DOI: 10.1021/jacs.3c06703 |
0.388 |
|
| 2023 |
Brown KA, Gellman SH. Effects of Replacing a Central Glycine Residue in GLP-1 on Receptor Affinity and Signaling Profile. Chembiochem : a European Journal of Chemical Biology. e202300504. PMID 37624685 DOI: 10.1002/cbic.202300504 |
0.305 |
|
| 2023 |
Yu Z, Kreitler DF, Chiu YTT, Xu R, Bruchs AT, Bingman CA, Gellman SH. Harnessing Aromatic-Histidine Interactions through Synergistic Backbone Extension and Side Chain Modification. Angewandte Chemie (International Ed. in English). e202308100. PMID 37587780 DOI: 10.1002/anie.202308100 |
0.333 |
|
| 2023 |
Qiu C, Whittaker GR, Gellman SH, Daniel S, Abbott NL. Interactions of SARS-CoV-2 and MERS-CoV Fusion Peptides Measured Using Single Molecule Force Methods. Biophysical Journal. PMID 36650897 DOI: 10.1016/j.bpj.2023.01.016 |
0.543 |
|
| 2022 |
Liu S, Yu Z, Daley EJ, Bingman CA, Bruchs AT, Gardella TJ, Gellman SH. Altered signaling at the PTH receptor via modified agonist contacts with the extracellular domain provides a path to prolonged agonism in vivo. Proceedings of the National Academy of Sciences of the United States of America. 119: e2212736119. PMID 36409914 DOI: 10.1073/pnas.2212736119 |
0.474 |
|
| 2022 |
Niu J, Qiu C, Abbott NL, Gellman SH. Formation of versus Recruitment to RNA-Rich Condensates: Controlling Effects Exerted by Peptide Side Chain Identity. Journal of the American Chemical Society. 144: 10386-10395. PMID 35639776 DOI: 10.1021/jacs.2c02222 |
0.46 |
|
| 2022 |
Niu J, Cederstrand AJ, Eddinger GA, Yin B, Checco JW, Bingman CA, Outlaw VK, Gellman SH. Trimer-to-Monomer Disruption Mechanism for a Potent, Protease-Resistant Antagonist of Tumor Necrosis Factor-α Signaling. Journal of the American Chemical Society. 144: 9610-9617. PMID 35613436 DOI: 10.1021/jacs.1c13717 |
0.764 |
|
| 2022 |
Andrews MK, Liu X, Gellman SH. Tailoring Reaction Selectivity by Modulating a Catalytic Diad on a Foldamer Scaffold. Journal of the American Chemical Society. PMID 35077169 DOI: 10.1021/jacs.1c11542 |
0.325 |
|
| 2021 |
White AD, Peña KA, Clark LJ, Maria CS, Liu S, Jean-Alphonse FG, Lee JY, Lei S, Cheng Z, Tu CL, Fang F, Szeto N, Gardella TJ, Xiao K, Gellman SH, et al. Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation. Science Signaling. 14: eabc5944. PMID 34609896 DOI: 10.1126/scisignal.abc5944 |
0.322 |
|
| 2021 |
Liu X, Gellman SH. Comparisons of β-Hairpin Propensity Among Peptides with Homochiral or Heterochiral Strands. Chembiochem : a European Journal of Chemical Biology. PMID 34288305 DOI: 10.1002/cbic.202100324 |
0.356 |
|
| 2021 |
Outlaw VK, Cheloha RW, Jurgens EM, Bovier FT, Zhu Y, Kreitler DF, Harder O, Niewiesk S, Porotto M, Gellman SH, Moscona A. Engineering Protease-Resistant Peptides to Inhibit Human Parainfluenza Viral Respiratory Infection. Journal of the American Chemical Society. PMID 33825470 DOI: 10.1021/jacs.1c01565 |
0.301 |
|
| 2021 |
Jones JB, Liu L, Rank LA, Wetzel D, Woods EC, Biok N, Anderson SE, Lee MR, Liu R, Huth S, Sandhu BK, Gellman SH, McBride SM. Cationic Homopolymers Inhibit Spore and Vegetative Cell Growth of . Acs Infectious Diseases. PMID 33739823 DOI: 10.1021/acsinfecdis.0c00843 |
0.577 |
|
| 2021 |
Wang C, Biok NA, Nayani K, Wang X, Yeon H, Derek Ma CK, Gellman SH, Abbott NL. Cationic Side Chain Identity Directs the Hydrophobically Driven Self-Assembly of Amphiphilic β-Peptides in Aqueous Solution. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 33683138 DOI: 10.1021/acs.langmuir.0c03255 |
0.682 |
|
| 2020 |
Outlaw VK, Kreitler DF, Stelitano D, Porotto M, Moscona A, Gellman SH. Effects of single α-to-β residue replacements on recognition of an extended segment in a viral fusion protein. Acs Infectious Diseases. PMID 32692914 DOI: 10.1021/Acsinfecdis.0C00385 |
0.424 |
|
| 2020 |
Checco JW, Eddinger GA, Rettko NJ, Chartier AR, Gellman SH. Tumor Necrosis Factor-α Trimer Disassembly and Inactivation via Peptide-Small Molecule Synergy. Acs Chemical Biology. PMID 32662976 DOI: 10.1021/Acschembio.0C00313 |
0.786 |
|
| 2020 |
Girvin ZC, Lampkin PP, Liu X, Gellman SH. Catalytic Intramolecular Conjugate Additions of Aldehyde-Derived Enamines to α,β-Unsaturated Esters. Organic Letters. 22: 4568-4573. PMID 32460501 DOI: 10.1021/Acs.Orglett.0C01666 |
0.317 |
|
| 2020 |
White AD, Jean-Alphonse FG, Fang F, Peña KA, Liu S, König GM, Inoue A, Aslanoglou D, Gellman SH, Kostenis E, Xiao K, Vilardaga JP. G-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR. Proceedings of the National Academy of Sciences of the United States of America. PMID 32184323 DOI: 10.1073/Pnas.1918158117 |
0.417 |
|
| 2020 |
Outlaw VK, Lemke JT, Zhu Y, Gellman SH, Porotto M, Moscona A. Structure-Guided Improvement of a Dual HPIV3/RSV Fusion Inhibitor. Journal of the American Chemical Society. PMID 31951396 DOI: 10.2210/Pdb6O40/Pdb |
0.312 |
|
| 2020 |
Liu S, Gellman SH. Preparation of β-Homologous Amino Acids Bearing Polar Side Chains via a Collective Synthesis Strategy. The Journal of Organic Chemistry. PMID 31920080 DOI: 10.1021/Acs.Joc.9B02562 |
0.567 |
|
| 2019 |
Girvin ZC, Andrews MK, Liu X, Gellman SH. Foldamer-templated catalysis of macrocycle formation. Science (New York, N.Y.). 366: 1528-1531. PMID 31857487 DOI: 10.1126/Science.Aax7344 |
0.396 |
|
| 2019 |
Biok NA, Passow AD, Wang C, Bingman CA, Abbott NL, Gellman SH. Retention of Coiled-Coil Dimer Formation in the Absence of Ion Pairing at Positions Flanking the Hydrophobic Core. Biochemistry. PMID 31738525 DOI: 10.1021/Acs.Biochem.9B00668 |
0.733 |
|
| 2019 |
Liu S, Jean-Alphonse FG, White AD, Wootten D, Sexton PM, Gardella TJ, Vilardaga JP, Gellman SH. Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism. Journal of the American Chemical Society. PMID 31496241 DOI: 10.1021/Jacs.9B04179 |
0.456 |
|
| 2019 |
Cheloha RW, Woodham AW, Bousbaine D, Wang T, Liu S, Sidney J, Sette A, Gellman SH, Ploegh HL. Recognition of Class II MHC Peptide Ligands That Contain β-Amino Acids. Journal of Immunology (Baltimore, Md. : 1950). PMID 31391235 DOI: 10.4049/Jimmunol.1900536 |
0.632 |
|
| 2019 |
Wang J, Cary BP, Beyer PD, Gellman SH, Weix DJ. Ketones from Nickel-Catalyzed Decarboxylative, Non-Symmetric Cross-Electrophile Coupling of Carboxylic Acid Esters. Angewandte Chemie (International Ed. in English). PMID 31287943 DOI: 10.1002/Anie.201906000 |
0.353 |
|
| 2019 |
Outlaw VK, Bottom-Tanzer S, Kreitler DF, Gellman SH, Porotto M, Moscona A. Dual Inhibition of Human Parainfluenza Type 3 and Respiratory Syncytial Virus Infectivity with a Single Agent. Journal of the American Chemical Society. PMID 31268705 DOI: 10.2210/Pdb6Nyx/Pdb |
0.336 |
|
| 2019 |
Cary BP, Hager MV, Gellman SH. Impact of substitution registry on receptor-activation profiles of backbone-modified glucagon-like peptide-1 analogues. Chembiochem : a European Journal of Chemical Biology. PMID 31172641 DOI: 10.1002/Cbic.201900300 |
0.454 |
|
| 2019 |
Kurgan KW, Kleman AF, Bingman CA, Kreitler DF, Weisblum B, Forest KT, Gellman SH. Retention of Native Quaternary Structure in Racemic Melittin Crystals. Journal of the American Chemical Society. PMID 31059253 DOI: 10.1021/Jacs.9B02691 |
0.409 |
|
| 2019 |
Yao Z, Cary BP, Bingman CA, Wang C, Kreitler DF, Satyshur KA, Forest KT, Gellman SH. Use of a Stereochemical Strategy To Probe the Mechanism of Phenol-Soluble Modulin α3 Toxicity. Journal of the American Chemical Society. PMID 31045358 DOI: 10.1021/Jacs.9B00349 |
0.612 |
|
| 2019 |
Kreitler DF, Yao Z, Steinkruger JD, Mortenson DE, Huang L, Mittal R, Travis BR, Forest KT, Gellman SH. A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation. Journal of the American Chemical Society. PMID 30645104 DOI: 10.1021/Jacs.8B11246 |
0.83 |
|
| 2018 |
Liu S, Cheloha RW, Watanabe T, Gardella TJ, Gellman SH. Receptor selectivity from minimal backbone modification of a polypeptide agonist. Proceedings of the National Academy of Sciences of the United States of America. PMID 30442659 DOI: 10.1073/Pnas.1815294115 |
0.579 |
|
| 2018 |
Girvin ZC, Gellman SH. Exploration of Diverse Reactive Diad Geometries for Bifunctional Catalysis via Foldamer Backbone Variation. Journal of the American Chemical Society. PMID 30226762 DOI: 10.1021/Jacs.8B05869 |
0.33 |
|
| 2018 |
Eddinger GA, Gellman SH. Differential Effects of β³- vs. β²-Amino Acid Residues on the Helicity and Recognition Properties of Bim BH3-Derived α/β-Peptides. Angewandte Chemie (International Ed. in English). PMID 30161284 DOI: 10.1002/Anie.201806909 |
0.483 |
|
| 2018 |
Fisher BF, Hong SH, Gellman SH. Thermodynamic Scale of β-Amino Acid Residue Propensities for an α-Helix-like Conformation. Journal of the American Chemical Society. PMID 30022665 DOI: 10.1021/Jacs.8B05162 |
0.473 |
|
| 2018 |
Shin YH, Gellman SH. Impact of Backbone Pattern and Residue Substitution on Helicity in α/β/γ-Peptides. Journal of the American Chemical Society. PMID 29350033 DOI: 10.1021/Jacs.7B10868 |
0.606 |
|
| 2017 |
Mortenson DE, Kreitler DF, Thomas NC, Guzei IA, Gellman SH, Forest KT. Evaluation of β-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure. Chembiochem : a European Journal of Chemical Biology. PMID 29272560 DOI: 10.1002/Cbic.201700580 |
0.793 |
|
| 2017 |
Wang C, Ma CD, Yeon H, Wang X, Gellman SH, Abbott NL. Non-Additive Interactions Mediated by Water at Chemically Heterogeneous Surfaces: Non-ionic Polar Groups and Hydrophobic Interactions. Journal of the American Chemical Society. PMID 29129065 DOI: 10.1021/Jacs.7B08367 |
0.678 |
|
| 2017 |
Thomas NC, Bartlett GJ, Woolfson DN, Gellman SH. Toward a Soluble Model System for the Amyloid State. Journal of the American Chemical Society. PMID 29116774 DOI: 10.1021/Jacs.7B07225 |
0.343 |
|
| 2017 |
Lee MR, Raman N, Gellman SH, Lynn DM, Palecek SP. Incorporation of β-peptides enhances the antifungal activity and selectivity of the helical antimicrobial peptide aurein 1.2. Acs Chemical Biology. PMID 29091404 DOI: 10.1021/Acschembio.7B00843 |
0.48 |
|
| 2017 |
Cheloha RW, Chen B, Kumar NN, Watanabe T, Thorne RG, Li L, Gardella TJ, Gellman SH. Development of Potent, Protease-Resistant Agonists of the Parathyroid Hormone Receptor with Broad β Residue Distribution. Journal of Medicinal Chemistry. PMID 29064243 DOI: 10.1021/Acs.Jmedchem.7B00876 |
0.384 |
|
| 2017 |
Fisher BF, Hong SH, Gellman SH. Helix Propensities of Amino Acid Residues via Thioester Exchange. Journal of the American Chemical Society. PMID 28898059 DOI: 10.1021/Jacs.7B07930 |
0.423 |
|
| 2017 |
Hager MV, Clydesdale L, Gellman SH, Sexton PM, Wootten D. Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1. Biochemical Pharmacology. PMID 28363772 DOI: 10.1016/J.Bcp.2017.03.018 |
0.404 |
|
| 2016 |
Checco JW, Gellman SH. Iterative non-proteinogenic residue incorporation yields α/β-peptides with a helix-loop-helix tertiary structure and high affinity for VEGF. Chembiochem : a European Journal of Chemical Biology. PMID 27897370 DOI: 10.1002/Cbic.201600545 |
0.794 |
|
| 2016 |
Hager MV, Johnson LM, Wootten D, Sexton PM, Gellman SH. β-Arrestin-Biased Agonists of the GLP-1 Receptor from β-Amino Acid Residue Incorporation into GLP-1 Analogues. Journal of the American Chemical Society. PMID 27813409 DOI: 10.1021/Jacs.6B08323 |
0.592 |
|
| 2016 |
Walsh PS, Blodgett KN, McBurney C, Gellman SH, Zwier TS. Inherent Conformational Preferences of Ac-Gln-Gln-NHBn: Sidechain Hydrogen Bonding Supports a β-Turn in the Gas Phase. Angewandte Chemie (International Ed. in English). PMID 27775204 DOI: 10.1002/Anie.201607842 |
0.38 |
|
| 2016 |
Cheloha RW, Watanabe T, Dean T, Gellman SH, Gardella TJ. Backbone Modification of a Parathyroid Hormone Receptor-1 Antagonist/Inverse Agonist. Acs Chemical Biology. PMID 27533344 DOI: 10.1021/Acschembio.6B00404 |
0.428 |
|
| 2016 |
Fisher BF, Gellman SH. Impact of γ-Amino Acid Residue Preorganization on α/γ-Peptide Foldamer Helicity in Aqueous Solution. Journal of the American Chemical Society. PMID 27529788 DOI: 10.1021/Jacs.6B06177 |
0.501 |
|
| 2016 |
MacDonald MJ, Lavis LD, Hilvert D, Gellman SH. Evaluation of the Ser-His Dipeptide, a Putative Catalyst of Amide and Ester Hydrolysis. Organic Letters. PMID 27400366 DOI: 10.1021/Acs.Orglett.6B01279 |
0.515 |
|
| 2016 |
Checco JW, Gellman SH. Targeting recognition surfaces on natural proteins with peptidic foldamers. Current Opinion in Structural Biology. 39: 96-105. PMID 27390896 DOI: 10.1016/J.Sbi.2016.06.014 |
0.784 |
|
| 2016 |
Kreitler DF, Mortenson DE, Forest KT, Gellman SH. Effects of Single α-to-β Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization. Journal of the American Chemical Society. PMID 27171550 DOI: 10.1021/Jacs.6B01454 |
0.79 |
|
| 2016 |
Walsh PS, Dean JC, McBurney C, Kang H, Gellman SH, Zwier TS. Conformation-specific spectroscopy of capped glutamine-containing peptides: role of a single glutamine residue on peptide backbone preferences. Physical Chemistry Chemical Physics : Pccp. PMID 27054830 DOI: 10.1039/C6Cp01062H |
0.489 |
|
| 2016 |
Ma CD, Acevedo-Vélez C, Wang C, Gellman SH, Abbott NL. Interaction of the Hydrophobic Tip of an Atomic Force Microscope with Oligopeptides Immobilized using Short and Long Tethers. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 26895750 DOI: 10.1021/Acs.Langmuir.5B04618 |
0.719 |
|
| 2015 |
Choi H, Chakraborty S, Liu R, Gellman SH, Weisshaar JC. Single-cell, Time-resolved Antimicrobial Effects of a Highly Cationic, Random Nylon-3 Copolymer on Live E. coli. Acs Chemical Biology. PMID 26493221 DOI: 10.1021/Acschembio.5B00547 |
0.518 |
|
| 2015 |
Mortenson DE, Steinkruger JD, Kreitler DF, Perroni DV, Sorenson GP, Huang L, Mittal R, Yun HG, Travis BR, Mahanthappa MK, Forest KT, Gellman SH. High-resolution structures of a heterochiral coiled coil. Proceedings of the National Academy of Sciences of the United States of America. PMID 26460035 DOI: 10.1073/Pnas.1507918112 |
0.841 |
|
| 2015 |
Kung VM, Cornilescu G, Gellman SH. Impact of Strand Number on Parallel β-Sheet Stability. Angewandte Chemie (International Ed. in English). PMID 26457984 DOI: 10.1002/Anie.201506448 |
0.372 |
|
| 2015 |
Hayouka Z, Thomas NC, Mortenson DE, Satyshur KA, Weisblum B, Forest KT, Gellman SH. Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif. Journal of the American Chemical Society. 137: 11884-7. PMID 26369301 DOI: 10.1021/Jacs.5B07206 |
0.806 |
|
| 2015 |
Checco JW, Lee EF, Evangelista M, Sleebs NJ, Rogers K, Pettikiriarachchi A, Kershaw NJ, Eddinger GA, Belair DG, Wilson JL, Eller CH, Raines RT, Murphy WL, Smith BJ, Gellman SH, et al. α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells. Journal of the American Chemical Society. 137: 11365-75. PMID 26317395 DOI: 10.1021/Jacs.5B05896 |
0.797 |
|
| 2015 |
Fisher BF, Guo L, Dolinar BS, Guzei IA, Gellman SH. Heterogeneous h-bonding in a foldamer helix. Journal of the American Chemical Society. 137: 6484-7. PMID 25974390 DOI: 10.1021/Jacs.5B03382 |
0.473 |
|
| 2015 |
Peterson-Kaufman KJ, Haase HS, Boersma MD, Lee EF, Fairlie WD, Gellman SH. Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics. Acs Chemical Biology. PMID 25946900 DOI: 10.1021/Acschembio.5B00109 |
0.824 |
|
| 2015 |
Demizu Y, Oba M, Okitsu K, Yamashita H, Misawa T, Tanaka M, Kurihara M, Gellman SH. A preorganized β-amino acid bearing a guanidinium side chain and its use in cell-penetrating peptides. Organic & Biomolecular Chemistry. 13: 5617-20. PMID 25897867 DOI: 10.1039/C5Ob00389J |
0.49 |
|
| 2015 |
Checco JW, Kreitler DF, Thomas NC, Belair DG, Rettko NJ, Murphy WL, Forest KT, Gellman SH. Targeting diverse protein-protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold. Proceedings of the National Academy of Sciences of the United States of America. 112: 4552-7. PMID 25825775 DOI: 10.1073/Pnas.1420380112 |
0.791 |
|
| 2015 |
Ma CD, Wang C, Acevedo-Vélez C, Gellman SH, Abbott NL. Modulation of hydrophobic interactions by proximally immobilized ions. Nature. 517: 347-50. PMID 25592540 DOI: 10.1038/Nature14018 |
0.676 |
|
| 2015 |
Cheloha RW, Sullivan JA, Wang T, Sand JM, Sidney J, Sette A, Cook ME, Suresh M, Gellman SH. Consequences of periodic α-to-β(3) residue replacement for immunological recognition of peptide epitopes. Acs Chemical Biology. 10: 844-54. PMID 25559929 DOI: 10.1021/Cb500888Q |
0.46 |
|
| 2014 |
Maynard SJ, Almeida AM, Yoshimi Y, Gellman SH. New charge-bearing amino acid residues that promote β-sheet secondary structure. Journal of the American Chemical Society. 136: 16683-8. PMID 25393077 DOI: 10.1021/Ja510265E |
0.827 |
|
| 2014 |
Giuliano MW, Maynard SJ, Almeida AM, Guo L, Guzei IA, Spencer LC, Gellman SH. A γ-amino acid that favors 12/10-helical secondary structure in α/γ-peptides. Journal of the American Chemical Society. 136: 15046-53. PMID 25301259 DOI: 10.1021/Ja5076585 |
0.84 |
|
| 2014 |
Liu R, Suárez JM, Weisblum B, Gellman SH, McBride SM. Synthetic polymers active against Clostridium difficile vegetative cell growth and spore outgrowth. Journal of the American Chemical Society. 136: 14498-504. PMID 25279431 DOI: 10.1021/Ja506798E |
0.576 |
|
| 2014 |
Chakraborty S, Liu R, Hayouka Z, Chen X, Ehrhardt J, Lu Q, Burke E, Yang Y, Weisblum B, Wong GC, Masters KS, Gellman SH. Ternary nylon-3 copolymers as host-defense peptide mimics: beyond hydrophobic and cationic subunits. Journal of the American Chemical Society. 136: 14530-5. PMID 25269798 DOI: 10.1021/Ja507576A |
0.598 |
|
| 2014 |
Johnson LM, Barrick S, Hager MV, McFedries A, Homan EA, Rabaglia ME, Keller MP, Attie AD, Saghatelian A, Bisello A, Gellman SH. A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo. Journal of the American Chemical Society. 136: 12848-51. PMID 25191938 DOI: 10.1021/Ja507168T |
0.655 |
|
| 2014 |
Choi H, Chakraborty S, Liu R, Gellman SH, Weisshaar JC. Medium effects on minimum inhibitory concentrations of nylon-3 polymers against E. coli. Plos One. 9: e104500. PMID 25153714 DOI: 10.1371/Journal.Pone.0104500 |
0.538 |
|
| 2014 |
Cheloha RW, Maeda A, Dean T, Gardella TJ, Gellman SH. Backbone modification of a polypeptide drug alters duration of action in vivo. Nature Biotechnology. 32: 653-5. PMID 24929976 DOI: 10.1038/Nbt.2920 |
0.312 |
|
| 2014 |
Lee MR, Raman N, Gellman SH, Lynn DM, Palecek SP. Hydrophobicity and helicity regulate the antifungal activity of 14-helical β-peptides. Acs Chemical Biology. 9: 1613-21. PMID 24837702 DOI: 10.1021/Cb500203E |
0.468 |
|
| 2014 |
Mayer C, Müller MM, Gellman SH, Hilvert D. Building proficient enzymes with foldamer prostheses. Angewandte Chemie (International Ed. in English). 53: 6978-81. PMID 24828837 DOI: 10.1002/Anie.201400945 |
0.579 |
|
| 2014 |
Lee MW, Chakraborty S, Schmidt NW, Murgai R, Gellman SH, Wong GC. Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides. Biochimica Et Biophysica Acta. 1838: 2269-79. PMID 24743021 DOI: 10.1016/J.Bbamem.2014.04.007 |
0.538 |
|
| 2014 |
Gord JR, Walsh PS, Fisher BF, Gellman SH, Zwier TS. Mimicking the first turn of an α-helix with an unnatural backbone: conformation-specific IR and UV spectroscopy of cyclically constrained β/γ-peptides. The Journal of Physical Chemistry. B. 118: 8246-56. PMID 24694352 DOI: 10.1021/Jp5015884 |
0.432 |
|
| 2014 |
Liu R, Chen X, Falk SP, Mowery BP, Karlsson AJ, Weisblum B, Palecek SP, Masters KS, Gellman SH. Structure-activity relationships among antifungal nylon-3 polymers: identification of materials active against drug-resistant strains of Candida albicans. Journal of the American Chemical Society. 136: 4333-42. PMID 24606327 DOI: 10.1021/Ja500036R |
0.302 |
|
| 2014 |
Liu R, Chen X, Chakraborty S, Lemke JJ, Hayouka Z, Chow C, Welch RA, Weisblum B, Masters KS, Gellman SH. Tuning the biological activity profile of antibacterial polymers via subunit substitution pattern. Journal of the American Chemical Society. 136: 4410-8. PMID 24601599 DOI: 10.1021/Ja500367U |
0.568 |
|
| 2014 |
Laaser JE, Skoff DR, Ho JJ, Joo Y, Serrano AL, Steinkruger JD, Gopalan P, Gellman SH, Zanni MT. Two-dimensional sum-frequency generation reveals structure and dynamics of a surface-bound peptide. Journal of the American Chemical Society. 136: 956-62. PMID 24372101 DOI: 10.1021/Ja408682S |
0.811 |
|
| 2014 |
Giuliano MW, Maynard SJ, Almeida AM, Reidenbach AG, Guo L, Ulrich EC, Guzei IA, Gellman SH. ChemInform Abstract: Evaluation of a Cyclopentane-Based γ-Amino Acid for the Ability to Promote α/γ-Peptide Secondary Structure. Cheminform. 45: no-no. DOI: 10.1002/CHIN.201421082 |
0.828 |
|
| 2013 |
Chakraborty S, Liu R, Lemke JJ, Hayouka Z, Welch RA, Weisblum B, Masters KS, Gellman SH. Effects of Cyclic vs. Acyclic Hydrophobic Subunits on the Chemical Structure and Biological Properties of Nylon-3 Co-Polymers. Acs Macro Letters. 2. PMID 24349873 DOI: 10.1021/Mz400239R |
0.562 |
|
| 2013 |
Mortenson DE, Kreitler DF, Yun HG, Gellman SH, Forest KT. Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain. Acta Crystallographica. Section D, Biological Crystallography. 69: 2506-12. PMID 24311591 DOI: 10.1107/S090744491302444X |
0.757 |
|
| 2013 |
Giuliano MW, Maynard SJ, Almeida AM, Reidenbach AG, Guo L, Ulrich EC, Guzei IA, Gellman SH. Evaluation of a cyclopentane-based γ-amino acid for the ability to promote α/γ-peptide secondary structure. The Journal of Organic Chemistry. 78: 12351-61. PMID 24303945 DOI: 10.1021/Jo401501G |
0.848 |
|
| 2013 |
Walsh PS, Kusaka R, Buchanan EG, James WH, Fisher BF, Gellman SH, Zwier TS. Cyclic constraints on conformational flexibility in γ-peptides: conformation specific IR and UV spectroscopy. The Journal of Physical Chemistry. A. 117: 12350-62. PMID 24147873 DOI: 10.1021/Jp408736T |
0.43 |
|
| 2013 |
Hayouka Z, Mortenson DE, Kreitler DF, Weisblum B, Forest KT, Gellman SH. Evidence for phenylalanine zipper-mediated dimerization in the X-ray crystal structure of a magainin 2 analogue. Journal of the American Chemical Society. 135: 15738-41. PMID 24102563 DOI: 10.1021/Ja409082W |
0.792 |
|
| 2013 |
Kusaka R, Zhang D, Walsh PS, Gord JR, Fisher BF, Gellman SH, Zwier TS. Role of ring-constrained γ-amino acid residues in α/γ-peptide folding: single-conformation UV and IR spectroscopy. The Journal of Physical Chemistry. A. 117: 10847-62. PMID 24070234 DOI: 10.1021/Jp408258W |
0.449 |
|
| 2013 |
Smith BJ, Lee EF, Checco JW, Evangelista M, Gellman SH, Fairlie WD. Structure-guided rational design of α/β-peptide foldamers with high affinity for BCL-2 family prosurvival proteins. Chembiochem : a European Journal of Chemical Biology. 14: 1564-72. PMID 23929624 DOI: 10.1002/Cbic.201300351 |
0.783 |
|
| 2013 |
Hayouka Z, Chakraborty S, Liu R, Boersma MD, Weisblum B, Gellman SH. Interplay among subunit identity, subunit proportion, chain length, and stereochemistry in the activity profile of sequence-random peptide mixtures. Journal of the American Chemical Society. 135: 11748-51. PMID 23909610 DOI: 10.1021/Ja406231B |
0.818 |
|
| 2013 |
Shin YH, Mortenson DE, Satyshur KA, Forest KT, Gellman SH. Differential impact of β and γ residue preorganization on α/β/γ-peptide helix stability in water. Journal of the American Chemical Society. 135: 8149-52. PMID 23701135 DOI: 10.1021/Ja403319Q |
0.841 |
|
| 2013 |
Liu R, Chen X, Hayouka Z, Chakraborty S, Falk SP, Weisblum B, Masters KS, Gellman SH. Nylon-3 polymers with selective antifungal activity. Journal of the American Chemical Society. 135: 5270-3. PMID 23547967 DOI: 10.1021/Ja4006404 |
0.496 |
|
| 2013 |
Johnson LM, Gellman SH. α-Helix mimicry with α/β-peptides. Methods in Enzymology. 523: 407-29. PMID 23422441 DOI: 10.1016/B978-0-12-394292-0.00019-9 |
0.679 |
|
| 2013 |
Arnold U, Huck BR, Gellman SH, Raines RT. Protein prosthesis: β-peptides as reverse-turn surrogates. Protein Science : a Publication of the Protein Society. 22: 274-9. PMID 23238807 DOI: 10.1002/Pro.2208 |
0.775 |
|
| 2013 |
Shin YH, Mortenson DE, Satyshur KA, Forest KT, Gellman SH. Differential Impact of beta and gamma Residue Preorganization on alpha / beta / gamma-Peptide Helix Stability in Water. Journal of the American Chemical Society. 135: 8149-8152. DOI: 10.2210/Pdb4Hjb/Pdb |
0.801 |
|
| 2013 |
Choi SH, Ivancic M, Guzei IA, Gellman SH. Structural characterization of peptide oligomers containing (1R,2S)-2-aminocyclohexanecarboxylic acid (cis-ACHC) European Journal of Organic Chemistry. 3464-3469. DOI: 10.1002/Ejoc.201300118 |
0.598 |
|
| 2012 |
Zhang J, Markiewicz MJ, Weisblum B, Stahl SS, Gellman SH. Functionally Diverse Nylon-3 Copolymers from Readily Accessible β-Lactams. Acs Macro Letters. 1: 714-717. PMID 23355958 DOI: 10.1021/Mz300172Y |
0.612 |
|
| 2012 |
Woys AM, Almeida AM, Wang L, Chiu CC, McGovern M, de Pablo JJ, Skinner JL, Gellman SH, Zanni MT. Parallel β-sheet vibrational couplings revealed by 2D IR spectroscopy of an isotopically labeled macrocycle: quantitative benchmark for the interpretation of amyloid and protein infrared spectra. Journal of the American Chemical Society. 134: 19118-28. PMID 23113791 DOI: 10.1021/Ja3074962 |
0.615 |
|
| 2012 |
Steinkruger JD, Bartlett GJ, Woolfson DN, Gellman SH. Strong contributions from vertical triads to helix-partner preferences in parallel coiled coils. Journal of the American Chemical Society. 134: 15652-5. PMID 22974448 DOI: 10.1021/Ja3063088 |
0.782 |
|
| 2012 |
Buchanan EG, James WH, Choi SH, Guo L, Gellman SH, Müller CW, Zwier TS. Single-conformation infrared spectra of model peptides in the amide I and amide II regions: experiment-based determination of local mode frequencies and inter-mode coupling. The Journal of Chemical Physics. 137: 094301. PMID 22957563 DOI: 10.1063/1.4747507 |
0.588 |
|
| 2012 |
Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Kruse AC, Manglik A, Cho KH, Nurva S, Gether U, Guan L, Loland CJ, Byrne B, Kobilka BK, Gellman SH. A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 9485-90. PMID 22730191 DOI: 10.1002/Chem.201200069 |
0.315 |
|
| 2012 |
Guo L, Zhang W, Guzei IA, Spencer LC, Gellman SH. New preorganized γ-amino acids as foldamer building blocks. Organic Letters. 14: 2582-5. PMID 22568480 DOI: 10.1021/Ol3008815 |
0.528 |
|
| 2012 |
Haase HS, Peterson-Kaufman KJ, Lan Levengood SK, Checco JW, Murphy WL, Gellman SH. Extending foldamer design beyond α-helix mimicry: α/β-peptide inhibitors of vascular endothelial growth factor signaling. Journal of the American Chemical Society. 134: 7652-5. PMID 22548447 DOI: 10.1021/Ja302469A |
0.812 |
|
| 2012 |
Johnson LM, Mortenson DE, Yun HG, Horne WS, Ketas TJ, Lu M, Moore JP, Gellman SH. Enhancement of α-helix mimicry by an α/β-peptide foldamer via incorporation of a dense ionic side-chain array. Journal of the American Chemical Society. 134: 7317-20. PMID 22524614 DOI: 10.1021/Ja302428D |
0.848 |
|
| 2012 |
Liu R, Masters KS, Gellman SH. Polymer chain length effects on fibroblast attachment on nylon-3-modified surfaces. Biomacromolecules. 13: 1100-5. PMID 22455338 DOI: 10.1021/Bm201847N |
0.346 |
|
| 2012 |
Steinkruger JD, Bartlett GJ, Hadley EB, Fay L, Woolfson DN, Gellman SH. The d'--d--d' vertical triad is less discriminating than the a'--a--a' vertical triad in the antiparallel coiled-coil dimer motif. Journal of the American Chemical Society. 134: 2626-33. PMID 22296518 DOI: 10.1021/Ja208855X |
0.802 |
|
| 2012 |
Mortenson DE, Satyshur KA, Guzei IA, Forest KT, Gellman SH. Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations. Journal of the American Chemical Society. 134: 2473-6. PMID 22280019 DOI: 10.1021/Ja210045S |
0.771 |
|
| 2012 |
Zhang J, Markiewicz MJ, Mowery BP, Weisblum B, Stahl SS, Gellman SH. C-terminal functionalization of nylon-3 polymers: effects of C-terminal groups on antibacterial and hemolytic activities. Biomacromolecules. 13: 323-31. PMID 22168316 DOI: 10.1021/Bm2013058 |
0.606 |
|
| 2012 |
Almeida AM, Li R, Gellman SH. Parallel β-sheet secondary structure is stabilized and terminated by interstrand disulfide cross-linking. Journal of the American Chemical Society. 134: 75-8. PMID 22148521 DOI: 10.1021/Ja208856C |
0.697 |
|
| 2012 |
Boersma MD, Haase HS, Peterson-Kaufman KJ, Lee EF, Clarke OB, Colman PM, Smith BJ, Horne WS, Fairlie WD, Gellman SH. Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain. Journal of the American Chemical Society. 134: 315-23. PMID 22040025 DOI: 10.1021/Ja207148M |
0.837 |
|
| 2012 |
Johnson LM, Mortenson DE, Yun HG, Horne WS, Ketas TJ, Lu M, Moore JP, Gellman SH. Enhancement of alpha-helix mimicry by an alpha / beta-peptide foldamer via incorporation of a dense ionic side-chain array. Journal of the American Chemical Society. 134: 7317-7320. DOI: 10.2210/Pdb4Dzv/Pdb |
0.825 |
|
| 2012 |
Guo L, Zhang W, Guzei IA, Spencer LC, Gellman SH. Helical secondary structures in 2:1 and 1:2 α/γ-peptide foldamers Tetrahedron. 68: 4413-4417. DOI: 10.1016/J.Tet.2012.01.079 |
0.528 |
|
| 2011 |
Buchanan EG, James WH, Gutberlet A, Dean JC, Guo L, Gellman SH, Zwier TS. Single-conformation spectroscopy and population analysis of model γ-peptides: new tests of amide stacking. Faraday Discussions. 150: 209-26; discussion 2. PMID 22457950 DOI: 10.1039/C1Fd00001B |
0.406 |
|
| 2011 |
Segman-Magidovich S, Lee MR, Vaiser V, Struth B, Gellman SH, Rapaport H. Sheet-like assemblies of charged amphiphilic α/β-peptides at the air-water interface. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 14857-66. PMID 22105992 DOI: 10.1002/Chem.201101775 |
0.482 |
|
| 2011 |
James WH, Buchanan EG, Müller CW, Dean JC, Kosenkov D, Slipchenko LV, Guo L, Reidenbach AG, Gellman SH, Zwier TS. Evolution of amide stacking in larger γ-peptides: triamide H-bonded cycles. The Journal of Physical Chemistry. A. 115: 13783-98. PMID 21978283 DOI: 10.1021/Jp205527E |
0.493 |
|
| 2011 |
James WH, Buchanan EG, Guo L, Gellman SH, Zwier TS. Competition between amide stacking and intramolecular H bonds in γ-peptide derivatives: controlling nearest-neighbor preferences. The Journal of Physical Chemistry. A. 115: 11960-70. PMID 21928850 DOI: 10.1021/Jp2081319 |
0.502 |
|
| 2011 |
Freire F, Gellman SH. Macrocyclic Design Strategies for Small, Stable Parallel β-Sheet Scaffolds. Journal of the American Chemical Society. 133: 12318. PMID 21927061 DOI: 10.1021/Ja2055148 |
0.433 |
|
| 2011 |
Pomerantz WC, Yuwono VM, Drake R, Hartgerink JD, Abbott NL, Gellman SH. Lyotropic liquid crystals formed from ACHC-rich β-peptides. Journal of the American Chemical Society. 133: 13604-13. PMID 21815636 DOI: 10.1021/Ja204874H |
0.82 |
|
| 2011 |
Freire F, Almeida AM, Fisk JD, Steinkruger JD, Gellman SH. Impact of strand length on the stability of parallel-β-sheet secondary structure. Angewandte Chemie (International Ed. in English). 50: 8735-8. PMID 21812082 DOI: 10.1002/Anie.201102986 |
0.825 |
|
| 2011 |
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, et al. Crystal structure of the β2 adrenergic receptor-Gs protein complex. Nature. 477: 549-55. PMID 21772288 DOI: 10.1038/Nature10361 |
0.318 |
|
| 2011 |
Lee EF, Smith BJ, Horne WS, Mayer KN, Evangelista M, Colman PM, Gellman SH, Fairlie WD. Structural basis of Bcl-xL recognition by a BH3-mimetic α/β-peptide generated by sequence-based design. Chembiochem : a European Journal of Chemical Biology. 12: 2025-32. PMID 21744457 DOI: 10.1002/Cbic.201100314 |
0.73 |
|
| 2011 |
Johnson LM, Horne WS, Gellman SH. Broad distribution of energetically important contacts across an extended protein interface. Journal of the American Chemical Society. 133: 10038-41. PMID 21644542 DOI: 10.1021/Ja203358T |
0.719 |
|
| 2011 |
Guo L, Zhang W, Reidenbach AG, Giuliano MW, Guzei IA, Spencer LC, Gellman SH. Characteristic structural parameters for the γ-peptide 14-helix: importance of subunit preorganization. Angewandte Chemie (International Ed. in English). 50: 5843-6. PMID 21567680 DOI: 10.1002/Anie.201101301 |
0.836 |
|
| 2011 |
Sawada T, Gellman SH. Structural mimicry of the α-helix in aqueous solution with an isoatomic α/β/γ-peptide backbone. Journal of the American Chemical Society. 133: 7336-9. PMID 21520956 DOI: 10.1021/Ja202175A |
0.543 |
|
| 2011 |
Acevedo-Vélez C, Andre G, Dufrêne YF, Gellman SH, Abbott NL. Single-molecule force spectroscopy of β-peptides that display well-defined three-dimensional chemical patterns. Journal of the American Chemical Society. 133: 3981-8. PMID 21361359 DOI: 10.1021/Ja1089183 |
0.617 |
|
| 2011 |
Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, et al. Structure and function of an irreversible agonist-β(2) adrenoceptor complex. Nature. 469: 236-40. PMID 21228876 DOI: 10.1038/Nature09665 |
0.323 |
|
| 2011 |
Thiele CM, Pomerantz WC, Abbott NL, Gellman SH. Lyotropic liquid crystalline phases from helical β-peptides as alignment media. Chemical Communications (Cambridge, England). 47: 502-4. PMID 20972503 DOI: 10.1039/C0Cc02123G |
0.794 |
|
| 2011 |
Boersma MD, Haase HS, Peterson-Kaufman KJ, Lee EF, Clarke OB, Colman PM, Smith BJ, Horne WS, Fairlie WD, Gellman SH. Evaluation of Diverse Alpha/Beta-Backbone Patterns for Functional Alpha-Helix Mimicry: Analogues of the Bim Bh3 Domain. Journal of the American Chemical Society. 134: 315. DOI: 10.2210/Pdb4A1U/Pdb |
0.79 |
|
| 2011 |
Lee EF, Smith BJ, Horne WS, Mayer KN, Evangelista M, Colman PM, Gellman SH, Fairlie WD. Cover Picture: Structural Basis of Bcl-xL Recognition by a BH3-Mimetic α/β-Peptide Generated by Sequence-Based Design (ChemBioChem 13/2011) Chembiochem. 12: 1941-1941. DOI: 10.1002/Cbic.201190058 |
0.672 |
|
| 2010 |
Chae PS, Laible PD, Gellman SH. Tripod Amphiphiles for Membrane Protein Manipulation. Molecular Biosystems. 6: 89-94. PMID 23814603 DOI: 10.1039/B915162C |
0.303 |
|
| 2010 |
Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Chandra R, Goren MA, Kruse AC, Nurva S, Loland CJ, Pierre Y, Drew D, Popot JL, Picot D, Fox BG, Guan L, ... ... Gellman SH, et al. Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins. Nature Methods. 7: 1003-8. PMID 21037590 DOI: 10.1038/Nmeth.1526 |
0.303 |
|
| 2010 |
Karlsson AJ, Flessner RM, Gellman SH, Lynn DM, Palecek SP. Polyelectrolyte multilayers fabricated from antifungal β-peptides: design of surfaces that exhibit antifungal activity against Candida albicans. Biomacromolecules. 11: 2321-8. PMID 20831274 DOI: 10.1021/Bm100424S |
0.348 |
|
| 2010 |
Choi SH, Guzei IA, Spencer LC, Gellman SH. Crystallographic characterization of 12-helical secondary structure in β-peptides containing side chain groups. Journal of the American Chemical Society. 132: 13879-85. PMID 20828159 DOI: 10.1021/Ja1062532 |
0.669 |
|
| 2010 |
Price JL, Horne WS, Gellman SH. Structural consequences of beta-amino acid preorganization in a self-assembling alpha/beta-peptide: fundamental studies of foldameric helix bundles. Journal of the American Chemical Society. 132: 12378-87. PMID 20718422 DOI: 10.1021/Ja103543S |
0.795 |
|
| 2010 |
Guo L, Almeida AM, Zhang W, Reidenbach AG, Choi SH, Guzei IA, Gellman SH. Helix formation in preorganized beta/gamma-peptide foldamers: hydrogen-bond analogy to the alpha-helix without alpha-amino acid residues. Journal of the American Chemical Society. 132: 7868-9. PMID 20491510 DOI: 10.1021/Ja103233A |
0.799 |
|
| 2010 |
Dohm MT, Mowery BP, Czyzewski AM, Stahl SS, Gellman SH, Barron AE. Biophysical mimicry of lung surfactant protein B by random nylon-3 copolymers. Journal of the American Chemical Society. 132: 7957-67. PMID 20481635 DOI: 10.1021/Ja909734N |
0.329 |
|
| 2010 |
Steinkruger JD, Woolfson DN, Gellman SH. Side-chain pairing preferences in the parallel coiled-coil dimer motif: insight on ion pairing between core and flanking sites. Journal of the American Chemical Society. 132: 7586-8. PMID 20465308 DOI: 10.1021/Ja100080Q |
0.786 |
|
| 2010 |
Chae PS, Guzei IA, Gellman SH. Crystallographic characterization of N-oxide tripod amphiphiles. Journal of the American Chemical Society. 132: 1953-9. PMID 20095541 DOI: 10.1021/Ja9085148 |
0.323 |
|
| 2010 |
James WH, Baquero EE, Choi SH, Gellman SH, Zwier TS. Laser spectroscopy of conformationally constrained alpha/beta-peptides: Ac-ACPC-Phe-NHMe and Ac-Phe-ACPC-NHMe. The Journal of Physical Chemistry. A. 114: 1581-91. PMID 20039717 DOI: 10.1021/Jp9090975 |
0.611 |
|
| 2010 |
Segman S, Lee MR, Vaiser V, Gellman SH, Rapaport H. Highly stable pleated-sheet secondary structure in assemblies of amphiphilic alpha/beta-peptides at the air-water interface. Angewandte Chemie (International Ed. in English). 49: 716-9. PMID 20025003 DOI: 10.1002/Anie.200904566 |
0.474 |
|
| 2010 |
Price JL, Hadley EB, Steinkruger JD, Gellman SH. Detection and analysis of chimeric tertiary structures by backbone thioester exchange: packing of an alpha helix against an alpha/beta-peptide helix. Angewandte Chemie (International Ed. in English). 49: 368-71. PMID 19967682 DOI: 10.1002/Anie.200904714 |
0.838 |
|
| 2010 |
Zhang J, Gellman SH, Stahl SS. Kinetics of anionic ring-opening polymerization of variously substituted β-lactams: Homopolymerization and copolymerization Macromolecules. 43: 5618-5626. DOI: 10.1021/Ma1010809 |
0.619 |
|
| 2010 |
Choi SH, Guzei IA, Spencer LC, Gellman SH. Erratum: Crystallographic characterization of 12-helical secondary structure in β-peptides containing side chain groups (Journal of the American Chemical Society (2010) 132 (13879-13885)) Journal of the American Chemical Society. 132. DOI: 10.1021/Ja1084354 |
0.449 |
|
| 2010 |
Lee H, LePlae PR, Porter EA, Gellman SH. ChemInform Abstract: An Efficient Route to Either Enantiomer of Orthogonally Protected trans-3-Aminopyrrolidine-4-carboxylic Acid (V). Cheminform. 32: no-no. DOI: 10.1002/chin.200138112 |
0.776 |
|
| 2010 |
Appella DH, Christianson LA, Klein DA, Richards MR, Powell DR, Gellman SH. ChemInform Abstract: Synthesis and Structural Characterization of Helix-Forming β-Peptides: trans-2-Aminocyclopentanecarboxylic Acid Oligomers. Cheminform. 30: no-no. DOI: 10.1002/chin.199952204 |
0.702 |
|
| 2009 |
Guo L, Chi Y, Almeida AM, Guzei IA, Parker BK, Gellman SH. Stereospecific synthesis of conformationally constrained gamma-amino acids: new foldamer building blocks that support helical secondary structure. Journal of the American Chemical Society. 131: 16018-20. PMID 19886693 DOI: 10.1021/Ja907233Q |
0.788 |
|
| 2009 |
Lee MR, Stahl SS, Gellman SH, Masters KS. Nylon-3 copolymers that generate cell-adhesive surfaces identified by library screening. Journal of the American Chemical Society. 131: 16779-89. PMID 19886604 DOI: 10.1021/Ja9050636 |
0.316 |
|
| 2009 |
James WH, Müller CW, Buchanan EG, Nix MG, Guo L, Roskop L, Gordon MS, Slipchenko LV, Gellman SH, Zwier TS. Intramolecular amide stacking and its competition with hydrogen bonding in a small foldamer. Journal of the American Chemical Society. 131: 14243-5. PMID 19757786 DOI: 10.1021/Ja9054965 |
0.493 |
|
| 2009 |
Horne WS, Johnson LM, Ketas TJ, Klasse PJ, Lu M, Moore JP, Gellman SH. Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers. Proceedings of the National Academy of Sciences of the United States of America. 106: 14751-6. PMID 19706443 DOI: 10.1073/Pnas.0902663106 |
0.776 |
|
| 2009 |
Pomerantz WC, Hadley EB, Fry CG, Gellman SH. In situ monitoring of backbone thioester exchange by 19F NMR. Chembiochem : a European Journal of Chemical Biology. 10: 2177-81. PMID 19644993 DOI: 10.1002/Cbic.200900380 |
0.809 |
|
| 2009 |
Mowery BP, Lindner AH, Weisblum B, Stahl SS, Gellman SH. Structure-activity relationships among random nylon-3 copolymers that mimic antibacterial host-defense peptides. Journal of the American Chemical Society. 131: 9735-45. PMID 19601684 DOI: 10.1021/Ja901613G |
0.488 |
|
| 2009 |
Giuliano MW, Horne WS, Gellman SH. An alpha/beta-peptide helix bundle with a pure beta3-amino acid core and a distinctive quaternary structure. Journal of the American Chemical Society. 131: 9860-1. PMID 19580264 DOI: 10.1021/Ja8099294 |
0.862 |
|
| 2009 |
Lu D, Windsor MA, Gellman SH, Keck JL. Peptide inhibitors identify roles for SSB C-terminal residues in SSB/exonuclease I complex formation. Biochemistry. 48: 6764-71. PMID 19527069 DOI: 10.1021/Bi900361R |
0.806 |
|
| 2009 |
Karlsson AJ, Pomerantz WC, Neilsen KJ, Gellman SH, Palecek SP. Effect of sequence and structural properties on 14-helical beta-peptide activity against Candida albicans planktonic cells and biofilms. Acs Chemical Biology. 4: 567-79. PMID 19518070 DOI: 10.1021/Cb900093R |
0.796 |
|
| 2009 |
Miller CA, Gellman SH, Abbott NL, de Pablo JJ. Association of helical beta-peptides and their aggregation behavior from the potential of mean force in explicit solvent. Biophysical Journal. 96: 4349-62. PMID 19486660 DOI: 10.1016/J.Bpj.2008.11.076 |
0.644 |
|
| 2009 |
Freire F, Gellman SH. Macrocyclic design strategies for small, stable parallel beta-sheet scaffolds. Journal of the American Chemical Society. 131: 7970-2. PMID 19456161 DOI: 10.1021/ja902210f |
0.367 |
|
| 2009 |
James WH, Baquero EE, Shubert VA, Choi SH, Gellman SH, Zwier TS. Single-conformation and diastereomer specific ultraviolet and infrared spectroscopy of model synthetic foldamers: alpha/beta-peptides. Journal of the American Chemical Society. 131: 6574-90. PMID 19366210 DOI: 10.1021/Ja901051V |
0.607 |
|
| 2009 |
Lee EF, Sadowsky JD, Smith BJ, Czabotar PE, Peterson-Kaufman KJ, Colman PM, Gellman SH, Fairlie WD. High-resolution structural characterization of a helical alpha/beta-peptide foldamer bound to the anti-apoptotic protein Bcl-xL. Angewandte Chemie (International Ed. in English). 48: 4318-22. PMID 19229915 DOI: 10.1002/Anie.200805761 |
0.751 |
|
| 2009 |
Choi SH, Guzei IA, Spencer LC, Gellman SH. Crystallographic characterization of helical secondary structures in 2:1 and 1:2 alpha/beta-peptides. Journal of the American Chemical Society. 131: 2917-24. PMID 19203269 DOI: 10.1021/Ja808168Y |
0.641 |
|
| 2009 |
Zhang J, Kissounko DA, Lee SE, Gellman SH, Stahl SS. Access to poly-beta-peptides with functionalized side chains and end groups via controlled ring-opening polymerization of beta-lactams. Journal of the American Chemical Society. 131: 1589-97. PMID 19125651 DOI: 10.1021/Ja8069192 |
0.719 |
|
| 2009 |
Müller MM, Windsor MA, Pomerantz WC, Gellman SH, Hilvert D. A rationally designed aldolase foldamer. Angewandte Chemie (International Ed. in English). 48: 922-5. PMID 19090515 DOI: 10.1002/Anie.200804996 |
0.797 |
|
| 2008 |
Pizzey CL, Pomerantz WC, Sung BJ, Yuwono VM, Gellman SH, Hartgerink JD, Yethiraj A, Abbott NL. Characterization of nanofibers formed by self-assembly of beta-peptide oligomers using small angle x-ray scattering. The Journal of Chemical Physics. 129: 095103. PMID 19044891 DOI: 10.1063/1.2955745 |
0.801 |
|
| 2008 |
Lee MR, Stahl SS, Gellman SH. Synthesis of beta-lactams bearing functionalized side chains from a readily available precursor. Organic Letters. 10: 5317-9. PMID 18956871 DOI: 10.1021/Ol802274X |
0.37 |
|
| 2008 |
Vaz E, Pomerantz WC, Geyer M, Gellman SH, Brunsveld L. Comparison of design strategies for promotion of beta-peptide 14-helix stability in water. Chembiochem : a European Journal of Chemical Biology. 9: 2254-9. PMID 18756554 DOI: 10.1002/Cbic.200800355 |
0.801 |
|
| 2008 |
Miller CA, Hernández-Ortiz JP, Abbott NL, Gellman SH, de Pablo JJ. Dipole-induced self-assembly of helical beta-peptides. The Journal of Chemical Physics. 129: 015102. PMID 18624501 DOI: 10.1063/1.2928700 |
0.645 |
|
| 2008 |
Miller CA, Gellman SH, Abbott NL, de Pablo JJ. Mechanical stability of helical beta-peptides and a comparison of explicit and implicit solvent models. Biophysical Journal. 95: 3123-36. PMID 18621835 DOI: 10.1529/Biophysj.108.134833 |
0.663 |
|
| 2008 |
Horne WS, Gellman SH. Foldamers with heterogeneous backbones. Accounts of Chemical Research. 41: 1399-408. PMID 18590282 DOI: 10.1021/Ar800009N |
0.737 |
|
| 2008 |
Horne WS, Price JL, Gellman SH. Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly. Proceedings of the National Academy of Sciences of the United States of America. 105: 9151-6. PMID 18587049 DOI: 10.1073/Pnas.0801135105 |
0.799 |
|
| 2008 |
Freire F, Fisk JD, Peoples AJ, Ivancic M, Guzei IA, Gellman SH. Diacid linkers that promote parallel beta-sheet secondary structure in water. Journal of the American Chemical Society. 130: 7839-41. PMID 18507461 DOI: 10.1021/Ja802042C |
0.646 |
|
| 2008 |
Boersma MD, Sadowsky JD, Tomita YA, Gellman SH. Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein-protein recognition: application to the Bim BH3 domain. Protein Science : a Publication of the Protein Society. 17: 1232-40. PMID 18467496 DOI: 10.1110/Ps.032896.107 |
0.81 |
|
| 2008 |
Choi SH, Guzei IA, Spencer LC, Gellman SH. Crystallographic characterization of helical secondary structures in alpha/beta-peptides with 1:1 residue alternation. Journal of the American Chemical Society. 130: 6544-50. PMID 18439014 DOI: 10.1021/Ja800355P |
0.653 |
|
| 2008 |
Peterson KJ, Sadowsky JD, Scheef EA, Pal S, Kourentzi KD, Willson RC, Bresnick EH, Sheibani N, Gellman SH. A fluorescence polarization assay for identifying ligands that bind to vascular endothelial growth factor Analytical Biochemistry. 378: 8-14. PMID 18413228 DOI: 10.1016/J.Ab.2008.03.043 |
0.675 |
|
| 2008 |
Zhu X, Koenig P, Gellman SH, Yethiraj A, Cui Q. Establishing effective simulation protocols for beta- and alpha/beta-peptides. II. Molecular mechanical (MM) model for a cyclic beta-residue. The Journal of Physical Chemistry. B. 112: 5439-48. PMID 18402479 DOI: 10.1021/Jp077601Y |
0.514 |
|
| 2008 |
Pomerantz WC, Grygiel TL, Lai JR, Gellman SH. Distinctive circular dichroism signature for 14-helix-bundle formation by beta-peptides. Organic Letters. 10: 1799-802. PMID 18396884 DOI: 10.1021/Ol800622E |
0.809 |
|
| 2008 |
Akkarawongsa R, Potocky TB, English EP, Gellman SH, Brandt CR. Inhibition of herpes simplex virus type 1 infection by cationic beta-peptides. Antimicrobial Agents and Chemotherapy. 52: 2120-9. PMID 18391029 DOI: 10.1128/Aac.01424-07 |
0.843 |
|
| 2008 |
Chi Y, Guo L, Kopf NA, Gellman SH. Enantioselective organocatalytic Michael addition of aldehydes to nitroethylene: efficient access to gamma2-amino acids. Journal of the American Chemical Society. 130: 5608-9. PMID 18386925 DOI: 10.1021/Ja800345R |
0.683 |
|
| 2008 |
Baquero EE, James WH, Choi SH, Gellman SH, Zwier TS. Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta3-hPhe-beta3-hAla-NHMe and Ac-beta3-hAla-beta3-hPhe-NHMe. Journal of the American Chemical Society. 130: 4795-807. PMID 18345673 DOI: 10.1021/Ja078272Q |
0.573 |
|
| 2008 |
Baquero EE, James WH, Choi SH, Gellman SH, Zwier TS. Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta3-hPhe-NHMe and Ac-beta3-hTyr-NHMe. Journal of the American Chemical Society. 130: 4784-94. PMID 18345672 DOI: 10.1021/Ja078271Y |
0.574 |
|
| 2008 |
Horne WS, Boersma MD, Windsor MA, Gellman SH. Sequence-based design of alpha/beta-peptide foldamers that mimic BH3 domains. Angewandte Chemie (International Ed. in English). 47: 2853-6. PMID 18330876 DOI: 10.1002/Anie.200705315 |
0.797 |
|
| 2008 |
Murray JK, Sadowsky JD, Scalf M, Smith LM, Tomita Y, Gellman SH. Exploration of structure--activity relationships among foldamer ligands for a specific protein binding site via parallel and split-and-mix library synthesis. Journal of Combinatorial Chemistry. 10: 204-15. PMID 18275161 DOI: 10.1021/Cc700153Z |
0.821 |
|
| 2008 |
Hadley EB, Testa OD, Woolfson DN, Gellman SH. Preferred side-chain constellations at antiparallel coiled-coil interfaces. Proceedings of the National Academy of Sciences of the United States of America. 105: 530-5. PMID 18184807 DOI: 10.1073/Pnas.0709068105 |
0.795 |
|
| 2008 |
Pomerantz WC, Yuwono VM, Pizzey CL, Hartgerink JD, Abbott NL, Gellman SH. Nanofibers and lyotropic liquid crystals from a class of self-assembling beta-peptides. Angewandte Chemie (International Ed. in English). 47: 1241-4. PMID 18183558 DOI: 10.1002/Anie.200704372 |
0.782 |
|
| 2008 |
Horne WS, Price JL, Gellman SH. Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, (9151-9156) DOI: 10.1073/pnas.0801135105) Proceedings of the National Academy of Sciences of the United States of America. 105: 17205. DOI: 10.1073/pnas.0808591105 |
0.513 |
|
| 2008 |
Chi Y, Guo L, Kopf NA, Gellman SH, Wiesner M, Revell JD, Tonazzi S, Wennemers H. Access to γ2-Amino Acids Synfacts. 2008: 648-648. DOI: 10.1055/S-2008-1072761 |
0.605 |
|
| 2008 |
Chi Y, Guo L, Kopf NA, Gellman SH. ChemInform Abstract: Enantioselective Organocatalytic Michael Addition of Aldehydes to Nitroethylene: Efficient Access to γ2-Amino Acids. Cheminform. 39. DOI: 10.1002/CHIN.200833059 |
0.505 |
|
| 2007 |
Mowery BP, Lee SE, Kissounko DA, Epand RF, Epand RM, Weisblum B, Stahl SS, Gellman SH. Mimicry of antimicrobial host-defense peptides by random copolymers. Journal of the American Chemical Society. 129: 15474-6. PMID 18034491 DOI: 10.1021/Ja077288D |
0.43 |
|
| 2007 |
Choi SH, Guzei IA, Gellman SH. Crystallographic characterization of the alpha/beta-peptide 14/15-helix. Journal of the American Chemical Society. 129: 13780-1. PMID 17949002 DOI: 10.1021/Ja0753344 |
0.653 |
|
| 2007 |
Cornilescu G, Hadley EB, Woll MG, Markley JL, Gellman SH, Cornilescu CC. Solution structure of a small protein containing a fluorinated side chain in the core. Protein Science : a Publication of the Protein Society. 16: 2089. PMID 17915350 DOI: 10.1110/Ps.062557707 |
0.805 |
|
| 2007 |
Hadley EB, Witek AM, Freire F, Peoples AJ, Gellman SH. Thermodynamic analysis of beta-sheet secondary structure by backbone thioester exchange. Angewandte Chemie (International Ed. in English). 46: 7056-9. PMID 17691093 DOI: 10.1002/Anie.200702449 |
0.8 |
|
| 2007 |
Tang L, Hopper ED, Tong Y, Sadowsky JD, Peterson KJ, Gellman SH, Fitzgerald MC. H/D exchange- and mass spectrometry-based strategy for the thermodynamic analysis of protein-ligand binding. Analytical Chemistry. 79: 5869-77. PMID 17580981 DOI: 10.1021/Ac0700777 |
0.668 |
|
| 2007 |
Potocky TB, Silvius J, Menon AK, Gellman SH. HeLa cell entry by guanidinium-rich beta-peptides: importance of specific cation-cell surface interactions. Chembiochem : a European Journal of Chemical Biology. 8: 917-26. PMID 17503427 DOI: 10.1002/Cbic.200600563 |
0.813 |
|
| 2007 |
Sadowsky JD, Murray JK, Tomita Y, Gellman SH. Exploration of backbone space in foldamers containing alpha- and beta-amino acid residues: developing protease-resistant oligomers that bind tightly to the BH3-recognition cleft of Bcl-xL. Chembiochem : a European Journal of Chemical Biology. 8: 903-16. PMID 17503422 DOI: 10.1002/Cbic.200600546 |
0.819 |
|
| 2007 |
Price JL, Horne WS, Gellman SH. Discrete heterogeneous quaternary structure formed by alpha/beta-peptide foldamers and alpha-peptides. Journal of the American Chemical Society. 129: 6376-7. PMID 17465552 DOI: 10.1021/Ja071203R |
0.804 |
|
| 2007 |
Chi Y, English EP, Pomerantz WC, Horne WS, Joyce LA, Alexander LR, Fleming WS, Hopkins EA, Gellman SH. Practical synthesis of enantiomerically pure beta2-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes. Journal of the American Chemical Society. 129: 6050-5. PMID 17439122 DOI: 10.1021/Ja070063I |
0.822 |
|
| 2007 |
Murray JK, Gellman SH. Targeting protein-protein interactions: lessons from p53/MDM2. Biopolymers. 88: 657-86. PMID 17427181 DOI: 10.1002/Bip.20741 |
0.674 |
|
| 2007 |
Murray JK, Gellman SH. Parallel synthesis of peptide libraries using microwave irradiation. Nature Protocols. 2: 624-31. PMID 17406623 DOI: 10.1038/Nprot.2007.23 |
0.717 |
|
| 2007 |
Lee MR, Raguse TL, Schinnerl M, Pomerantz WC, Wang X, Wipf P, Gellman SH. Origins of the high 14-helix propensity of cyclohexyl-rigidified residues in beta-peptides. Organic Letters. 9: 1801-4. PMID 17394351 DOI: 10.1021/Ol070511R |
0.855 |
|
| 2007 |
Horne WS, Price JL, Keck JL, Gellman SH. Helix bundle quaternary structure from alpha/beta-peptide foldamers. Journal of the American Chemical Society. 129: 4178-80. PMID 17362016 DOI: 10.1021/Ja070396F |
0.792 |
|
| 2007 |
Schmitt MA, Weisblum B, Gellman SH. Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides. Journal of the American Chemical Society. 129: 417-28. PMID 17212422 DOI: 10.1021/Ja0666553 |
0.79 |
|
| 2007 |
Sadowsky JD, Fairlie WD, Hadley EB, Lee HS, Umezawa N, Nikolovska-Coleska Z, Wang S, Huang DC, Tomita Y, Gellman SH. (alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions. Journal of the American Chemical Society. 129: 139-54. PMID 17199293 DOI: 10.1021/Ja0662523 |
0.836 |
|
| 2007 |
Bell CM, Kissounko DA, Gellman SH, Stahl SS. Catalytic metathesis of simple secondary amides. Angewandte Chemie (International Ed. in English). 46: 761-3. PMID 17163571 DOI: 10.1002/Anie.200603588 |
0.304 |
|
| 2007 |
Cornilescu G, Hadley EB, Woll MG, Markley JL, Gellman SH, Cornilescu CC. Solution structure of a small protein containing a fluorinated side chain in the core. Protein Science : a Publication of the Protein Society. 16: 14-9. PMID 17123960 DOI: 10.1110/ps.062557707 |
0.806 |
|
| 2007 |
Pomerantz WC, Cadwell KD, Hsu YJ, Gellman SH, Abbott NL. Sequence dependent behavior of amphiphilic β-peptides on gold surfaces Chemistry of Materials. 19: 4436-4441. DOI: 10.1021/Cm070265D |
0.794 |
|
| 2006 |
Hadley EB, Gellman SH. An antiparallel alpha-helical coiled-coil model system for rapid assessment of side-chain recognition at the hydrophobic interface. Journal of the American Chemical Society. 128: 16444-5. PMID 17177361 DOI: 10.1021/Ja067178R |
0.784 |
|
| 2006 |
Lai JR, Epand RF, Weisblum B, Epand RM, Gellman SH. Roles of salt and conformation in the biological and physicochemical behavior of protegrin-1 and designed analogues: correlation of antimicrobial, hemolytic, and lipid bilayer-perturbing activities. Biochemistry. 45: 15718-30. PMID 17176094 DOI: 10.1021/Bi0617759 |
0.678 |
|
| 2006 |
Woll MG, Hadley EB, Mecozzi S, Gellman SH. Stabilizing and destabilizing effects of phenylalanine --> F5-phenylalanine mutations on the folding of a small protein. Journal of the American Chemical Society. 128: 15932-3. PMID 17165695 DOI: 10.1021/Ja0634573 |
0.79 |
|
| 2006 |
Karlsson AJ, Pomerantz WC, Weisblum B, Gellman SH, Palecek SP. Antifungal activity from 14-helical beta-peptides. Journal of the American Chemical Society. 128: 12630-1. PMID 17002340 DOI: 10.1021/Ja064630Y |
0.795 |
|
| 2006 |
Pal S, Wu J, Murray JK, Gellman SH, Wozniak MA, Keely PJ, Boyer ME, Gomez TM, Hasso SM, Fallon JF, Bresnick EH. An antiangiogenic neurokinin-B/thromboxane A2 regulatory axis. The Journal of Cell Biology. 174: 1047-58. PMID 17000881 DOI: 10.1083/Jcb.200603152 |
0.586 |
|
| 2006 |
Rathore N, Gellman SH, de Pablo JJ. Thermodynamic stability of beta-peptide helices and the role of cyclic residues. Biophysical Journal. 91: 3425-35. PMID 16905613 DOI: 10.1529/Biophysj.106.084491 |
0.537 |
|
| 2006 |
Pomerantz WC, Abbott NL, Gellman SH. Lyotropic liquid crystals from designed helical beta-peptides. Journal of the American Chemical Society. 128: 8730-1. PMID 16819857 DOI: 10.1021/Ja062412Z |
0.814 |
|
| 2006 |
Fisk JD, Schmitt MA, Gellman SH. Thermodynamic analysis of autonomous parallel beta-sheet formation in water. Journal of the American Chemical Society. 128: 7148-9. PMID 16734453 DOI: 10.1021/Ja060942P |
0.791 |
|
| 2006 |
Chi Y, Gellman SH. Enantioselective organocatalytic aminomethylation of aldehydes: a role for ionic interactions and efficient access to beta2-amino acids. Journal of the American Chemical Society. 128: 6804-5. PMID 16719457 DOI: 10.1021/Ja061731N |
0.641 |
|
| 2006 |
Schmitt MA, Choi SH, Guzei IA, Gellman SH. New helical foldamers: heterogeneous backbones with 1:2 and 2:1 alpha:beta-amino acid residue patterns. Journal of the American Chemical Society. 128: 4538-9. PMID 16594667 DOI: 10.1021/Ja060281W |
0.793 |
|
| 2006 |
Epand RF, Schmitt MA, Gellman SH, Epand RM. Role of membrane lipids in the mechanism of bacterial species selective toxicity by two alpha/beta-antimicrobial peptides. Biochimica Et Biophysica Acta. 1758: 1343-50. PMID 16564494 DOI: 10.1016/J.Bbamem.2006.01.018 |
0.764 |
|
| 2006 |
Murray JK, Gellman SH. Microwave-assisted parallel synthesis of a 14-helical beta-peptide library. Journal of Combinatorial Chemistry. 8: 58-65. PMID 16398554 DOI: 10.1021/Cc0501099 |
0.731 |
|
| 2006 |
English EP, Chumanov RS, Gellman SH, Compton T. Rational development of beta-peptide inhibitors of human cytomegalovirus entry. The Journal of Biological Chemistry. 281: 2661-7. PMID 16275647 DOI: 10.1074/Jbc.M508485200 |
0.828 |
|
| 2006 |
Cornilescu C, Cornilescu G, Hadley E, Gellman S, Markley J. Solution structure of chicken villin headpiece subdomain containing a fluorinated side chain in the core Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Jm0/Pdb |
0.762 |
|
| 2006 |
Pal S, Wu J, Murray JK, Gellman SH, Wozniak MA, Keely PJ, Boyer ME, Gomez TM, Hasso SM, Fallon JF, Bresnick EH. Correction: Ubp6 delays destruction Journal of Cell Biology. 175: 671-671. DOI: 10.1083/Jcb.20060315220061030C |
0.58 |
|
| 2005 |
Epand RF, Schmitt MA, Gellman SH, Sen A, Auger M, Hughes DW, Epand RM. Bacterial species selective toxicity of two isomeric alpha/beta-peptides: role of membrane lipids. Molecular Membrane Biology. 22: 457-69. PMID 16373318 DOI: 10.1080/09687860500370562 |
0.772 |
|
| 2005 |
Murray JK, Farooqi B, Sadowsky JD, Scalf M, Freund WA, Smith LM, Chen J, Gellman SH. Efficient synthesis of a beta-peptide combinatorial library with microwave irradiation. Journal of the American Chemical Society. 127: 13271-80. PMID 16173757 DOI: 10.1021/Ja052733V |
0.838 |
|
| 2005 |
Schmitt MA, Choi SH, Guzei IA, Gellman SH. Residue requirements for helical folding in short alpha/beta-peptides: crystallographic characterization of the 11-helix in an optimized sequence. Journal of the American Chemical Society. 127: 13130-1. PMID 16173725 DOI: 10.1021/Ja0536163 |
0.803 |
|
| 2005 |
Chi Y, Gellman SH. Diphenylprolinol methyl ether: a highly enantioselective catalyst for Michael addition of aldehydes to simple enones. Organic Letters. 7: 4253-6. PMID 16146400 DOI: 10.1021/Ol0517729 |
0.481 |
|
| 2005 |
Sadowsky JD, Schmitt MA, Lee HS, Umezawa N, Wang S, Tomita Y, Gellman SH. Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition. Journal of the American Chemical Society. 127: 11966-8. PMID 16117535 DOI: 10.1021/Ja053678T |
0.83 |
|
| 2005 |
Peelen TJ, Chi Y, Gellman SH. Enantioselective organocatalytic Michael additions of aldehydes to enones with imidazolidinones: cocatalyst effects and evidence for an enamine intermediate. Journal of the American Chemical Society. 127: 11598-9. PMID 16104725 DOI: 10.1021/Ja0532584 |
0.518 |
|
| 2005 |
Porter EA, Weisblum B, Gellman SH. Use of parallel synthesis to probe structure-activity relationships among 12-helical beta-peptides: evidence of a limit on antimicrobial activity. Journal of the American Chemical Society. 127: 11516-29. PMID 16089482 DOI: 10.1021/Ja0519785 |
0.804 |
|
| 2005 |
Chi Y, Peelen TJ, Gellman SH. A rapid 1H NMR assay for enantiomeric excess of alpha-substituted aldehydes. Organic Letters. 7: 3469-72. PMID 16048319 DOI: 10.1021/Ol051174U |
0.533 |
|
| 2005 |
Theisen MJ, Potocky TB, McQuade DT, Gellman SH, Chiu ML. Crystallization of bacteriorhodopsin solubilized by a tripod amphiphile. Biochimica Et Biophysica Acta. 1751: 213-6. PMID 15963773 DOI: 10.1016/J.Bbapap.2005.04.011 |
0.764 |
|
| 2005 |
Eldred SE, Pancost MR, Otte KM, Rozema D, Stahl SS, Gellman SH. Effects of side chain configuration and backbone spacing on the gene delivery properties of lysine-derived cationic polymers. Bioconjugate Chemistry. 16: 694-9. PMID 15898739 DOI: 10.1021/Bc050017C |
0.387 |
|
| 2005 |
Huck BR, Gellman SH. Synthesis of 2,2-disubstituted pyrrolidine-4-carboxylic acid derivatives and their incorporation into beta-peptide oligomers. The Journal of Organic Chemistry. 70: 3353-62. PMID 15844969 DOI: 10.1021/Jo048639Z |
0.803 |
|
| 2005 |
Murray JK, Gellman SH. Application of microwave irradiation to the synthesis of 14-helical beta-peptides. Organic Letters. 7: 1517-20. PMID 15816741 DOI: 10.1021/Ol0501727 |
0.749 |
|
| 2005 |
Espinosa JF, Syud FA, Gellman SH. An autonomously folding beta-hairpin derived from the human YAP65 WW domain: attempts to define a minimum ligand-binding motif. Biopolymers. 80: 303-11. PMID 15800888 DOI: 10.1002/Bip.20205 |
0.793 |
|
| 2005 |
Potocky TB, Menon AK, Gellman SH. Effects of conformational stability and geometry of guanidinium display on cell entry by beta-peptides. Journal of the American Chemical Society. 127: 3686-7. PMID 15771489 DOI: 10.1021/Ja042566J |
0.811 |
|
| 2005 |
De Stasio G, Schmitt MA, Gellman SH. Spectromicroscopy at the organic-inorganic interface in biominerals American Journal of Science. 305: 673-686. DOI: 10.2475/Ajs.305.6-8.673 |
0.705 |
|
| 2005 |
Gelman MA, Gellman SH. Using Constrained β-Amino Acid Residues to Control β-Peptide Shape and Function Enantioselective Synthesis of β-Amino Acids: Second Edition. 527-591. DOI: 10.1002/0471698482.ch22 |
0.824 |
|
| 2004 |
Peelen TJ, Chi Y, English EP, Gellman SH. Synthesis of 4,4-disubstituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into 12-helical beta-peptides. Organic Letters. 6: 4411-4. PMID 15548038 DOI: 10.1021/Ol0483293 |
0.864 |
|
| 2004 |
Woll MG, Gellman SH. Backbone thioester exchange: a new approach to evaluating higher order structural stability in polypeptides. Journal of the American Chemical Society. 126: 11172-4. PMID 15355097 DOI: 10.1021/Ja046891I |
0.802 |
|
| 2004 |
Lai JR, Fisk JD, Weisblum B, Gellman SH. Hydrophobic core repacking in a coiled-coil dimer via phage display: insights into plasticity and specificity at a protein-protein interface. Journal of the American Chemical Society. 126: 10514-5. PMID 15327289 DOI: 10.1021/Ja047710F |
0.717 |
|
| 2004 |
Epand RF, Raguse TL, Gellman SH, Epand RM. Antimicrobial 14-helical beta-peptides: potent bilayer disrupting agents. Biochemistry. 43: 9527-35. PMID 15260496 DOI: 10.1021/Bi049414L |
0.852 |
|
| 2004 |
Schmitt MA, Weisblum B, Gellman SH. Unexpected relationships between structure and function in alpha,beta-peptides: antimicrobial foldamers with heterogeneous backbones. Journal of the American Chemical Society. 126: 6848-9. PMID 15174837 DOI: 10.1021/Ja048546Z |
0.771 |
|
| 2004 |
Langenhan JM, Gellman SH. Effects of alternative side chain pairings and reverse turn sequences on antiparallel sheet structure in beta-peptide hairpins. Organic Letters. 6: 937-40. PMID 15012069 DOI: 10.1021/Ol0364430 |
0.808 |
|
| 2004 |
Gelman MA, Weisblum B, Lynn DM, Gellman SH. Biocidal activity of polystyrenes that are cationic by virtue of protonation. Organic Letters. 6: 557-60. PMID 14961622 DOI: 10.1021/Ol036341+ |
0.807 |
|
| 2004 |
Hayen A, Schmitt MA, Ngassa FN, Thomasson KA, Gellman SH. Two helical conformations from a single foldamer backbone: "split personality" in short alpha/beta-peptides. Angewandte Chemie (International Ed. in English). 43: 505-10. PMID 14735547 DOI: 10.1002/Anie.200352125 |
0.775 |
|
| 2003 |
Huck BR, Fisk JD, Guzei IA, Carlson HA, Gellman SH. Secondary structural preferences of 2,2-disubstituted pyrrolidine-4-carboxylic acid oligomers: beta-peptide foldamers that cannot form internal hydrogen bonds. Journal of the American Chemical Society. 125: 9035-7. PMID 15369358 DOI: 10.1021/Ja034561C |
0.821 |
|
| 2003 |
Potocky TB, Menon AK, Gellman SH. Cytoplasmic and nuclear delivery of a TAT-derived peptide and a beta-peptide after endocytic uptake into HeLa cells. The Journal of Biological Chemistry. 278: 50188-94. PMID 14517218 DOI: 10.1074/Jbc.M308719200 |
0.801 |
|
| 2003 |
Gelman MA, Richter S, Cao H, Umezawa N, Gellman SH, Rana TM. Selective binding of TAR RNA by a Tat-derived beta-peptide. Organic Letters. 5: 3563-5. PMID 14507173 DOI: 10.1021/Ol034977V |
0.835 |
|
| 2003 |
Brückner AM, Chakraborty P, Gellman SH, Diederichsen U. Molecular architecture with functionalized beta-peptide helices. Angewandte Chemie (International Ed. in English). 42: 4395-9. PMID 14502721 DOI: 10.1002/Anie.200351871 |
0.483 |
|
| 2003 |
Langenhan JM, Gellman SH. Preparation of protected syn-alpha,beta-dialkyl beta-amino acids that contain polar side chain functionality. The Journal of Organic Chemistry. 68: 6440-3. PMID 12895085 DOI: 10.1021/Jo034583H |
0.769 |
|
| 2003 |
Park JS, Lee HS, Lai JR, Kim BM, Gellman SH. Accommodation of alpha-substituted residues in the beta-peptide 12-helix: expanding the range of substitution patterns available to a foldamer scaffold. Journal of the American Chemical Society. 125: 8539-45. PMID 12848561 DOI: 10.1021/Ja034180Z |
0.772 |
|
| 2003 |
Langenhan JM, Guzei IA, Gellman SH. Parallel sheet secondary structure in beta-peptides. Angewandte Chemie (International Ed. in English). 42: 2402-5. PMID 12783508 DOI: 10.1002/Anie.200350932 |
0.797 |
|
| 2003 |
Raguse TL, Lai JR, Gellman SH. Environment-independent 14-helix formation in short beta-peptides: striking a balance between shape control and functional diversity. Journal of the American Chemical Society. 125: 5592-3. PMID 12733872 DOI: 10.1021/Ja0341485 |
0.859 |
|
| 2003 |
Epand RF, Umezawa N, Porter EA, Gellman SH, Epand RM. Interactions of the antimicrobial beta-peptide beta-17 with phospholipid vesicles differ from membrane interactions of magainins. European Journal of Biochemistry / Febs. 270: 1240-8. PMID 12631282 DOI: 10.1046/J.1432-1033.2003.03484.X |
0.774 |
|
| 2003 |
Lai JR, Gellman SH. Reinvestigation of the proposed folding and self-association of the Neuropeptide Head Activator. Protein Science : a Publication of the Protein Society. 12: 560-6. PMID 12592026 DOI: 10.1110/Ps.0232103 |
0.681 |
|
| 2003 |
Lee HS, Park JS, Kim BM, Gellman SH. Efficient synthesis of enantiomerically pure beta2-amino acids via chiral isoxazolidinones. The Journal of Organic Chemistry. 68: 1575-8. PMID 12585907 DOI: 10.1021/Jo026738B |
0.627 |
|
| 2003 |
Syud FA, Stanger HE, Mortell HS, Espinosa JF, Fisk JD, Fry CG, Gellman SH. Influence of strand number on antiparallel beta-sheet stability in designed three- and four-stranded beta-sheets. Journal of Molecular Biology. 326: 553-68. PMID 12559922 DOI: 10.1016/S0022-2836(02)01304-9 |
0.83 |
|
| 2003 |
Syud FA, Stanger HE, Schenck Mortell H, Espinosa JF, Fisk JD, Fry CG, Gellman SH. Corrigendum to “Influence of Strand Number on Antiparallel β-Sheet Stability in Designed Three- and Four-Stranded β-Sheets” Journal of Molecular Biology. 328: 303. DOI: 10.1016/S0022-2836(03)00303-6 |
0.784 |
|
| 2003 |
Schinnerl M, Murray J, Langenhan J, Gellman S. Asymmetric Synthesis of a New Helix-Forming β-Amino Acid: trans-4-Aminopiperidine-3-carboxylic Acid European Journal of Organic Chemistry. 2003: 721-726. DOI: 10.1002/Ejoc.200390112 |
0.829 |
|
| 2003 |
Brückner AM, Garcia M, Marsh A, Gellman SH, Diederichsen U. Synthesis of Novel Nucleo‐β‐Amino Acids and Nucleobase‐Functionalized β‐Peptides European Journal of Organic Chemistry. 2003: 3555-3561. DOI: 10.1002/Ejoc.200300269 |
0.392 |
|
| 2003 |
Langenhan JM, Gellman SH. Preparation of Protected syn-α,β-Dialkyl β-Amino Acids that Contain Polar Side Chain Functionality. Cheminform. 34. DOI: 10.1002/CHIN.200349072 |
0.712 |
|
| 2003 |
Brückner AM, Chakraborty P, Gellman SH, Diederichsen U. Molekulare Architektur mit funktionalisiertenβ-Peptid-Helices Angewandte Chemie. 115: 4532-4536. DOI: 10.1002/Ange.200351871 |
0.472 |
|
| 2002 |
Raguse TL, Porter EA, Weisblum B, Gellman SH. Structure-activity studies of 14-helical antimicrobial beta-peptides: probing the relationship between conformational stability and antimicrobial potency. Journal of the American Chemical Society. 124: 12774-85. PMID 12392424 DOI: 10.1021/Ja0270423 |
0.859 |
|
| 2002 |
Woll MG, Fisk JD, LePlae PR, Gellman SH. Stereoselective synthesis of 3-substituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into short 12-helical beta-peptides that fold in water. Journal of the American Chemical Society. 124: 12447-52. PMID 12381185 DOI: 10.1021/Ja0258778 |
0.847 |
|
| 2002 |
Lai JR, Huck BR, Weisblum B, Gellman SH. Design of non-cysteine-containing antimicrobial beta-hairpins: structure-activity relationship studies with linear protegrin-1 analogues. Biochemistry. 41: 12835-42. PMID 12379126 DOI: 10.1021/Bi026127D |
0.838 |
|
| 2002 |
Porter EA, Wang X, Schmitt MA, Gellman SH. Synthesis and 12-helical secondary structure of beta-peptides containing (2R,3R)-aminoproline. Organic Letters. 4: 3317-9. PMID 12227778 DOI: 10.1021/Ol0266370 |
0.841 |
|
| 2002 |
Arnold U, Hinderaker MP, Nilsson BL, Huck BR, Gellman SH, Raines RT. Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turn. Journal of the American Chemical Society. 124: 8522-3. PMID 12121081 DOI: 10.1021/Ja026114N |
0.78 |
|
| 2002 |
Porter EA, Weisblum B, Gellman SH. Mimicry of host-defense peptides by unnatural oligomers: antimicrobial beta-peptides. Journal of the American Chemical Society. 124: 7324-30. PMID 12071741 DOI: 10.1021/Ja0260871 |
0.798 |
|
| 2002 |
LePlae PR, Fisk JD, Porter EA, Weisblum B, Gellman SH. Tolerance of acyclic residues in the beta-peptide 12-helix: access to diverse side-chain arrays for biological applications. Journal of the American Chemical Society. 124: 6820-1. PMID 12059191 DOI: 10.1021/Ja017869H |
0.858 |
|
| 2002 |
Gellman SH, Woolfson DN. Mini-proteins Trp the light fantastic. Nature Structural Biology. 9: 408-10. PMID 12032551 DOI: 10.1038/Nsb0602-408 |
0.403 |
|
| 2002 |
Espinosa JF, Syud FA, Gellman SH. Analysis of the factors that stabilize a designed two-stranded antiparallel beta-sheet. Protein Science : a Publication of the Protein Society. 11: 1492-505. PMID 12021448 DOI: 10.1110/Ps.4140102 |
0.819 |
|
| 2002 |
Hilario J, Kubelka J, Syud FA, Gellman SH, Keiderling TA. Spectroscopic characterization of selected beta- sheet hairpin models. Biopolymers. 67: 233-6. PMID 12012436 DOI: 10.1002/Bip.10094 |
0.775 |
|
| 2002 |
Umezawa N, Gelman MA, Haigis MC, Raines RT, Gellman SH. Translocation of a beta-peptide across cell membranes. Journal of the American Chemical Society. 124: 368-9. PMID 11792194 DOI: 10.1021/Ja017283V |
0.856 |
|
| 2002 |
Knight SM, Umezawa N, Lee HS, Gellman SH, Kay BK. A fluorescence polarization assay for the identification of inhibitors of the p53-DM2 protein-protein interaction. Analytical Biochemistry. 300: 230-6. PMID 11779115 DOI: 10.1006/Abio.2001.5468 |
0.567 |
|
| 2002 |
Porter EA, Wang X, Schmitt MA, Gellman SH. Synthesis and 12-helical secondary structure of β-peptides containing (2R,3R)-Aminoproline Organic Letters. 4: 3317-3319. DOI: 10.1021/ol0266370 |
0.815 |
|
| 2002 |
Raguse TL, Porter EA, Weisblum B, Gellman SH. Structure - Activity studies of 14-helical antimicrobial β-peptides: Probing the relationship between conformational stability and antimicrobial potency Journal of the American Chemical Society. 124: 12774-12785. DOI: 10.1021/ja0270423 |
0.833 |
|
| 2002 |
Raguse TL, Lai JR, Gellman SH. Evidence that the β-peptide 14-helix is stabilized by β3-residues with side-chain branching adjacent to the β-carbon atom Helvetica Chimica Acta. 85: 4154-4164. DOI: 10.1002/Hlca.200290001 |
0.825 |
|
| 2001 |
Raguse TL, Lai JR, LePlae PR, Gellman SH. Toward beta-peptide tertiary structure: self-association of an amphiphilic 14-helix in aqueous solution. Organic Letters. 3: 3963-6. PMID 11720580 DOI: 10.1021/Ol016868R |
0.847 |
|
| 2001 |
Cheng RP, Gellman SH, DeGrado WF. beta-Peptides: from structure to function. Chemical Reviews. 101: 3219-32. PMID 11710070 DOI: 10.1021/Cr000045I |
0.495 |
|
| 2001 |
Woll MG, Lai JR, Guzei IA, Taylor SJ, Smith ME, Gellman SH. Parallel sheet secondary structure in gamma-peptides. Journal of the American Chemical Society. 123: 11077-8. PMID 11686719 DOI: 10.1021/Ja011719P |
0.836 |
|
| 2001 |
Stanger HE, Syud FA, Espinosa JF, Giriat I, Muir T, Gellman SH. Length-dependent stability and strand length limits in antiparallel beta -sheet secondary structure. Proceedings of the National Academy of Sciences of the United States of America. 98: 12015-20. PMID 11593011 DOI: 10.1073/Pnas.211536998 |
0.821 |
|
| 2001 |
Syud FA, Stanger HE, Gellman SH. Interstrand side chain--side chain interactions in a designed beta-hairpin: significance of both lateral and diagonal pairings. Journal of the American Chemical Society. 123: 8667-77. PMID 11535071 DOI: 10.1021/Ja0109803 |
0.801 |
|
| 2001 |
LePlae PR, Umezawa N, Lee HS, Gellman SH. An efficient route to either enantiomer of trans-2-aminocyclopentanecarboxylic acid. The Journal of Organic Chemistry. 66: 5629-32. PMID 11485497 DOI: 10.1021/Jo010279H |
0.778 |
|
| 2001 |
Langenhan JM, Fisk JD, Gellman SH. Evaluation of hydrogen bonding complementarity between a secondary sulfonamide and an alpha-amino acid residue. Organic Letters. 3: 2559-62. PMID 11483060 DOI: 10.1021/Ol016237X |
0.809 |
|
| 2001 |
Lee HS, Syud FA, Wang X, Gellman SH. Diversity in short beta-peptide 12-helices: high-resolution structural analysis in aqueous solution of a hexamer containing sulfonylated pyrrolidine residues. Journal of the American Chemical Society. 123: 7721-2. PMID 11481004 DOI: 10.1021/Ja010734R |
0.85 |
|
| 2001 |
McKay SL, Haptonstall B, Gellman SH. Beyond the hydrophobic effect: attractions involving heteroaromatic rings in aqueous solution. Journal of the American Chemical Society. 123: 1244-5. PMID 11456685 DOI: 10.1021/Ja003256D |
0.706 |
|
| 2001 |
Fisk JD, Gellman SH. A parallel beta-sheet model system that folds in water. Journal of the American Chemical Society. 123: 343-4. PMID 11456526 DOI: 10.1021/Ja002493D |
0.563 |
|
| 2001 |
Lee HS, LePlae PR, Porter EA, Gellman SH. An efficient route to either enantiomer of orthogonally protected trans-3-aminopyrrolidine-4-carboxylic acid. The Journal of Organic Chemistry. 66: 3597-9. PMID 11348151 DOI: 10.1021/Jo001534L |
0.779 |
|
| 2001 |
Espinosa JF, Muñoz V, Gellman SH. Interplay between hydrophobic cluster and loop propensity in beta-hairpin formation. Journal of Molecular Biology. 306: 397-402. PMID 11178900 DOI: 10.1006/Jmbi.2000.4349 |
0.436 |
|
| 2001 |
Chung YJ, Huck BR, Christianson LA, Stanger HE, Krauthäuser S, Powell DR, Gellman SH. Stereochemical Control of Hairpin Formation in β-Peptides Containing Dinipecotic Acid Reverse Turn Segments [J. Am. Chem. Soc.2000,122, 3995−4004]. Journal of the American Chemical Society. 123: 5851-5851. DOI: 10.1021/Ja0151549 |
0.785 |
|
| 2001 |
Cheng RP, Gellman SH, DeGrado WF. β-peptides: From structure to function Chemical Reviews. 101: 3219-3232. DOI: 10.1021/cr000045i |
0.372 |
|
| 2000 |
Yu SM, McQuade DT, Quinn MA, Hackenberger CP, Krebs MP, Polans AS, Gellman SH. An improved tripod amphiphile for membrane protein solubilization. Protein Science : a Publication of the Protein Society. 9: 2518-27. PMID 11206073 DOI: 10.1110/Ps.9.12.2518 |
0.602 |
|
| 2000 |
Huck BR, Fisk JD, Gellman SH. Promotion of sheet formation in alpha-peptide strands by a beta-peptide reverse turn. Organic Letters. 2: 2607-10. PMID 10990408 DOI: 10.1021/Ol006120T |
0.856 |
|
| 2000 |
Appella DH, LePlae PR, Raguse TL, Gellman SH. (R,R,R)-2,5-diaminocylohexanecarboxylic acid, a building block for water-soluble, helix-forming beta-peptides. The Journal of Organic Chemistry. 65: 4766-9. PMID 10959893 DOI: 10.1021/Jo000277H |
0.799 |
|
| 2000 |
Gardner RR, McKay SL, Gellman SH. Solvent-dependent stabilization of the E configuration of propargylic secondary amides. Organic Letters. 2: 2335-8. PMID 10930277 DOI: 10.1021/Ol006096J |
0.712 |
|
| 2000 |
Porter EA, Wang X, Lee HS, Weisblum B, Gellman SH. Non-haemolytic beta-amino-acid oligomers. Nature. 404: 565. PMID 10766230 DOI: 10.1038/35007145 |
0.806 |
|
| 2000 |
McQuade DT, Quinn MA, Yu SM, Polans AS, Krebs MP, Gellman SH. Rigid Amphiphiles for Membrane Protein Manipulation. Angewandte Chemie (International Ed. in English). 39: 758-761. PMID 10760860 DOI: 10.1002/(Sici)1521-3757(20000218)112:4<774::Aid-Ange774>3.0.Co;2-W |
0.564 |
|
| 2000 |
Chung YJ, Huck BR, Christianson LA, Stanger HE, Krauthäuser S, Powell DR, Gellman SH. Stereochemical control of hairpin formation in β-peptides containing dinipecotic acid reverse turn segments Journal of the American Chemical Society. 122: 3995-4004. DOI: 10.1021/Ja993416P |
0.796 |
|
| 2000 |
Barchi JJ, Huang X, Appella DH, Christianson LA, Durell SR, Gellman SH. Solution conformations of helix-forming β-amino acid homooligomers Journal of the American Chemical Society. 122: 2711-2718. DOI: 10.1021/Ja9930014 |
0.686 |
|
| 2000 |
Fisk JD, Powell DR, Gellman SH. Control of hairpin formation via proline configuration in parallel β- sheet model systems Journal of the American Chemical Society. 122: 5443-5447. DOI: 10.1021/Ja9929483 |
0.607 |
|
| 2000 |
Wang X, Espinosa JF, Gellman SH. 12-Helix Formation in Aqueous Solution with Short β-Peptides Containing Pyrrolidine-Based Residues Journal of the American Chemical Society. 122: 4821-4822. DOI: 10.1021/Ja000093K |
0.472 |
|
| 2000 |
Christianson LA, Lucero MJ, Appella DH, Klein DA, Gellman SH. Improved treatment of cyclic ?-amino acids and successful prediction of ?-peptide secondary structure using a modified force field: AMBER*C Journal of Computational Chemistry. 21: 763-773. DOI: 10.1002/(Sici)1096-987X(20000715)21:9<763::Aid-Jcc5>3.0.Co;2-C |
0.65 |
|
| 1999 |
Huck BR, Langenhan JM, Gellman SH. Non-hydrogen-bonded secondary structure in beta-peptides: evidence from circular dichroism of (S)-pyrrolidine-3-carboxylic acid oligomers and (S)-nipecotic acid oligomers. Organic Letters. 1: 1717-20. PMID 10836030 DOI: 10.1021/Ol9909482 |
0.819 |
|
| 1999 |
Syud FA, Espinosa JF, Gellman SH. NMR-based quanfification of β-sheet populations in aqueous solution through use of reference peptides for the folded and unfolded states [6] Journal of the American Chemical Society. 121: 11577-11578. DOI: 10.1021/Ja992733T |
0.794 |
|
| 1999 |
Appella DH, Christianson LA, Klein DA, Richards MR, Powell DR, Gellman SH. Synthesis and structural characterization of helix-forming β-peptides: Trans-2-aminocyclopentanecarboxylic acid oligomers Journal of the American Chemical Society. 121: 7574-7581. DOI: 10.1021/Ja991185G |
0.734 |
|
| 1999 |
Appella DH, Christianson LA, Karle IL, Powell DR, Gellman SH. Synthesis and characterization of trans-2-aminocyclohexanecarboxylic acid oligomers: An unnatural helical secondary structure and implications for β-peptide tertiary structure Journal of the American Chemical Society. 121: 6206-6212. DOI: 10.1021/Ja990748L |
0.724 |
|
| 1999 |
Daugherty DL, Gellman SH. A fluorescence assay for leucine zipper dimerization: Avoiding unintended consequences of fluorophore attachment Journal of the American Chemical Society. 121: 4325-4333. DOI: 10.1021/Ja990178P |
0.314 |
|
| 1999 |
Appella DH, Barchi JJ, Durell SR, Gellman SH. Formation of short, stable helices in aqueous solution by β-amino acid hexamers [2] Journal of the American Chemical Society. 121: 2309-2310. DOI: 10.1021/Ja983918N |
0.657 |
|
| 1999 |
Gardner RR, Liang aG, Gellman SH. β-Turn and β-Hairpin Mimicry with Tetrasubstituted Alkenes Journal of the American Chemical Society. 121: 1806-1816. DOI: 10.1021/Ja9824526 |
0.377 |
|
| 1998 |
Gellman SH. Minimal model systems for beta sheet secondary structure in proteins. Current Opinion in Chemical Biology. 2: 717-25. PMID 9914187 DOI: 10.1016/S1367-5931(98)80109-9 |
0.454 |
|
| 1998 |
Chung YJ, Christianson LA, Stanger HE, Powell DR, Gellman SH. A β-Peptide Reverse Turn that Promotes Hairpin Formation Journal of the American Chemical Society. 120: 10555-10556. DOI: 10.1021/Ja982249A |
0.447 |
|
| 1998 |
Applequist J, Bode KA, Appella DH, Christianson LA, Gellman SH. Theoretical and Experimental Circular Dichroic Spectra of the Novel Helical Foldamer Poly[(1R,2R)-trans-2-aminocyclopentanecarboxylic acid] Journal of the American Chemical Society. 120: 4891-4892. DOI: 10.1021/Ja9742186 |
0.597 |
|
| 1998 |
Stanger HE, Gellman SH. Rules for Antiparallel β-Sheet Design: d-Pro-Gly Is Superior tol-Asn-Gly for β-Hairpin Nucleation1 Journal of the American Chemical Society. 120: 4236-4237. DOI: 10.1021/Ja973704Q |
0.306 |
|
| 1998 |
Gellman SH. Foldamers: A Manifesto Accounts of Chemical Research. 31: 173-180. DOI: 10.1021/Ar960298R |
0.313 |
|
| 1997 |
Appella DH, Christianson LA, Klein DA, Powell DR, Huang X, Barchi JJ, Gellman SH. Residue-based control of helix shape in β-peptide oligomers Nature. 387: 381-384. PMID 9163422 DOI: 10.1038/387381A0 |
0.766 |
|
| 1997 |
Krauthäuser S, Christianson LA, Powell DR, Gellman SH. Antiparallel Sheet Formation in β-Peptide Foldamers: Effects of β-Amino Acid Substitution on Conformational Preference1 Journal of the American Chemical Society. 119: 11719-11720. DOI: 10.1021/Ja9730627 |
0.462 |
|
| 1997 |
McQuade DT, McKay SL, Powell DR, Gellman SH. Indifference to hydrogen bonding in a family of secondary amides Journal of the American Chemical Society. 119: 8528-8532. DOI: 10.1021/Ja9711019 |
0.773 |
|
| 1997 |
Haque TS, Gellman SH. Insights on β-Hairpin Stability in Aqueous Solution from Peptides with Enforced Type I‘ and Type II‘ β-Turns Journal of the American Chemical Society. 119: 2303-2304. DOI: 10.1021/Ja963653H |
0.388 |
|
| 1997 |
Holmgren SK, Savage PB, Desper JM, Schladetzky KD, Powell DR, Gellman SH. Steric control of oxidation selectivity in macrycyclic phosphine oxide-dithioethers Tetrahedron. 53: 12249-12262. DOI: 10.1016/S0040-4020(97)00557-7 |
0.453 |
|
| 1996 |
Appella DH, Christianson LA, Karle IL, Powell DR, Gellman SH. β-Peptide foldamers: Robust helix formation in a new family of β-amino acid oligomers Journal of the American Chemical Society. 118: 13071-13072. DOI: 10.1021/Ja963290L |
0.687 |
|
| 1996 |
Schenck HL, Dado GP, Gellman SH. Redox-Triggered Secondary Structure Changes in the Aggregated States of a Designed Methionine-Rich Peptide Journal of the American Chemical Society. 118: 12487-12494. DOI: 10.1021/Ja962026P |
0.508 |
|
| 1996 |
Haque TS, Little JC, Gellman SH. Stereochemical Requirements for β-Hairpin Formation: Model Studies with Four-Residue Peptides and Depsipeptides Journal of the American Chemical Society. 118: 6975-6985. DOI: 10.1021/Ja960429J |
0.374 |
|
| 1995 |
Gardner RR, Gellman SH. Evaluation of the Conformation-Directing Effects of Secondary Hydrogen-Bonding Interactions in Flexible Tetrapeptide Analogs Journal of the American Chemical Society. 117: 10411-10412. DOI: 10.1021/Ja00146A038 |
0.3 |
|
| 1995 |
Newcomb LF, Haque TS, Gellman SH. Searching for Minimum Increments of Hydrophobic Collapse: Flexible Dinaphthyl Carboxylates Journal of the American Chemical Society. 117: 6509-6519. DOI: 10.1021/Ja00129A014 |
0.31 |
|
| 1995 |
McQuade DT, Barrett DG, Desper JM, Hayashi RK, Gellman SH. Effects of amphiphilic topology on self-association in solution, at the air-water interface, and in the solid state Journal of the American Chemical Society. 117: 4862-4869. DOI: 10.1021/Ja00122A017 |
0.559 |
|
| 1995 |
Gardner RR, Liang G, Gellman SH. An Achiral Dipeptide Mimetic That Promotes .beta.-Hairpin Formation Journal of the American Chemical Society. 117: 3280-3281. DOI: 10.1021/Ja00116A036 |
0.36 |
|
| 1994 |
Gallo EA, Gellman SH. Effect of a C-Terminal Cationic Group on the Competition between .alpha.-Helical Turn and .beta.-Turn in a Model Depsipeptide Journal of the American Chemical Society. 116: 11560-11561. DOI: 10.1021/Ja00104A043 |
0.377 |
|
| 1994 |
Haque TS, Little JC, Gellman SH. Mirror Image Reverse Turns Promote Beta -Hairpin Formation Journal of the American Chemical Society. 116: 4105-4106. DOI: 10.1021/Ja00088A067 |
0.325 |
|
| 1994 |
Savage PB, Holmgren SK, Gellman SH. Anion and ion pair complexation by a macrocyclic phosphine oxide disulfoxide Journal of the American Chemical Society. 116: 4069-4070. DOI: 10.1021/Ja00088A049 |
0.443 |
|
| 1994 |
Dado GP, Gellman SH. Intramolecular Hydrogen Bonding in Derivatives of .beta.-Alanine and .gamma.-Amino Butyric Acid; Model Studies for the Folding of Unnatural Polypeptide Backbones Journal of the American Chemical Society. 116: 1054-1062. DOI: 10.1021/Ja00082A029 |
0.393 |
|
| 1994 |
Barrett DG, Liang GB, McQuade DT, Desper JM, Schladetzky KD, Gellman SH. Synthetic studies on the 1,6-methano[10]annulene skeleton: A new route that provides derivatives substituted at the bridge and on the annulene ring Journal of the American Chemical Society. 116: 10525-10532. |
0.541 |
|
| 1993 |
Savage PB, Holmgren SK, Desper JM, Gellman SH. Macrocycles containing sulfur and phosphorus: Structure and complexation properties Pure and Applied Chemistry. 65: 461-466. DOI: 10.1351/Pac199365030461 |
0.483 |
|
| 1993 |
Dado GP, Gellman SH. Redox control of secondary structure in a designed peptide Journal of the American Chemical Society. 115: 12609-12610. DOI: 10.1021/Ja00079A060 |
0.434 |
|
| 1993 |
Savage PB, Gellman SH. Complexation of hexosammonium ions: evidence for contributions from OH.cntdot..cntdot..cntdot.OH hydrogen bonds in a hydroxylic medium Journal of the American Chemical Society. 115: 10448-10449. DOI: 10.1021/Ja00075A106 |
0.469 |
|
| 1993 |
Gallo EA, Gellman SH. Hydrogen-bond-mediated folding in depsipeptide models of .beta.-turns and .alpha.-helical turns Journal of the American Chemical Society. 115: 9774-9788. DOI: 10.1021/Ja00074A052 |
0.456 |
|
| 1993 |
Savage PB, Holmgren SK, Gellman SH. Optimization of a phosphine oxide disulfoxide array for multipoint hydrogen bonding to ammonium ions Journal of the American Chemical Society. 115: 7900-7901. DOI: 10.1021/Ja00070A055 |
0.463 |
|
| 1992 |
Dado GP, Desper JM, Holmgren SK, Rito CJ, Gellman SH. Effects of covalent modifications on the solid-state folding and packing of N-malonylglycine derivatives Journal of the American Chemical Society. 114: 4834-4843. DOI: 10.1021/Ja00038A057 |
0.31 |
|
| 1992 |
Liang GB, Rito CJ, Gellman SH. Thermodynamic analysis of .beta.-turn formation in Pro-Ala, Pro-Gly, and Pro-Val model peptides in methylene chloride Journal of the American Chemical Society. 114: 4440-4442. DOI: 10.1021/Ja00037A083 |
0.496 |
|
| 1992 |
Savage PB, Desper JM, Gellman SH. Stereoselective oxidation of an eleven-membered heterocycle Tetrahedron Letters. 33: 2107-2110. DOI: 10.1016/0040-4039(92)88152-U |
0.475 |
|
| 1992 |
Gellman SH, Powell DR, Desper JM. An unusual hydrogen bonding pattern in a crystallographically observed β-turn Tetrahedron Letters. 33: 1963-1964. DOI: 10.1016/0040-4039(92)88114-K |
0.322 |
|
| 1991 |
Gellman SH. On the role of methionine residues in the sequence-independent recognition of nonpolar protein surfaces. Biochemistry. 30: 6633-6. PMID 2065050 DOI: 10.1021/Bi00241A001 |
0.303 |
|
| 1986 |
Gellman SH, Petter R, Breslow R. Catalytic hydrolysis of a phosphate triester by tetracoordinated zinc complexes. Journal of the American Chemical Society. 108: 2388-94. PMID 22175588 DOI: 10.1021/Ja00269A041 |
0.439 |
|
| 1985 |
Svastits EW, Dawson JH, Breslow R, Gellman SH. Functionalized nitrogen atom transfer catalyzed by cytochrome P-450 Journal of the American Chemical Society. 107: 6427-6428. DOI: 10.1021/Ja00308A064 |
0.41 |
|
| 1983 |
Breslow R, Gellman SH. Intramolecular nitrene carbon-hydrogen insertions mediated by transition-metal complexes as nitrogen analogs of cytochrome P-450 reactions Journal of the American Chemical Society. 105: 6728-6729. DOI: 10.1021/Ja00360A039 |
0.43 |
|
| 1982 |
Breslow R, Gellman SH. Tosylamidation of cyclohexane by a cytochrome P-450 model Journal of the Chemical Society, Chemical Communications. 1400-1401. DOI: 10.1039/C39820001400 |
0.411 |
|
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