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Steven S. An, Ph.D. - Publications

Affiliations: 
2000 Brown University, Providence, RI 
Area:
General Biophysics
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57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Yeung BH, Huang J, An SS, Solway J, Mitzner W, Tang WY. Role of Isocitrate Dehydrogenase 2 on DNA Hydroxymethylation in Human Airway Smooth Muscle Cells. American Journal of Respiratory Cell and Molecular Biology. PMID 32150688 DOI: 10.1165/Rcmb.2019-0323Oc  0.381
2019 Perez-Gonzalez NA, Rochman ND, Yao K, Tao J, Le MT, Flanary S, Sablich L, Toler B, Crentsil E, Takaesu F, Lambrus B, Huang J, Fu V, Chengappa P, Jones TM, ... ... An S, et al. YAP and TAZ regulate cell volume. The Journal of Cell Biology. PMID 31481532 DOI: 10.1083/Jcb.201902067  0.338
2019 Kilic O, Yoon A, Shah SR, Yong HM, Ruiz-Valls A, Chang H, Panettieri RA, Liggett SB, Quiñones-Hinojosa A, An SS, Levchenko A. A microphysiological model of the bronchial airways reveals the interplay of mechanical and biochemical signals in bronchospasm. Nature Biomedical Engineering. PMID 31150010 DOI: 10.1038/S41551-019-0366-7  0.386
2019 Hughes RM, Simons BW, Khan H, Miller R, Kugler V, Torquato S, Theodros D, Haffner MC, Lotan TL, Huang J, Davicioni E, An SS, Riddle RC, Thorek DL, Garraway IP, et al. Asporin Restricts Mesenchymal Stromal Cell Differentiation, Alters the Tumor Microenvironment, and Drives Metastatic Progression. Cancer Research. PMID 31123087 DOI: 10.1158/0008-5472.Can-18-2931  0.311
2019 Ojiaku CA, Chung E, Parikh V, Williams JK, Schwab A, Fuentes AL, Corpuz ML, Lui V, Paek S, Bexiga NM, Narayan S, Nunez FJ, Ahn K, Ostrom RS, An SS, et al. TGF-β1 Decreases β2-Agonist-Induced Relaxation in Human Airway Smooth Muscle. American Journal of Respiratory Cell and Molecular Biology. PMID 30742476 DOI: 10.1165/Rcmb.2018-0301Oc  0.34
2019 Hyun Jo M, Choul Kim B, An SS, Ha T. Molecular Force of Airway Smooth Muscle Cell during Contraction Biophysical Journal. 116: 415a-416a. DOI: 10.1016/J.Bpj.2018.11.2240  0.372
2018 Kim DH, Ewald AJ, Park J, Kshitiz, Kwak M, Gray RS, Su CY, Seo J, An SS, Levchenko A. Biomechanical interplay between anisotropic re-organization of cells and the surrounding matrix underlies transition to invasive cancer spread. Scientific Reports. 8: 14210. PMID 30242256 DOI: 10.1038/S41598-018-32010-3  0.323
2018 Zhu W, Kim BC, Wang M, Huang J, Isak A, Bexiga NM, Monticone R, Ha T, Lakatta EG, An SS. TGFβ1 reinforces arterial aging in the vascular smooth muscle cell through a long-range regulation of the cytoskeletal stiffness. Scientific Reports. 8: 2668. PMID 29422510 DOI: 10.1038/S41598-018-20763-W  0.368
2017 Pera T, Deshpande DA, Ippolito M, Wang B, Gavrila A, Michael JV, Nayak AP, Tompkins E, Farrell E, Kroeze WK, Roth BL, Panettieri RA, Benovic JL, An SS, Dulin NO, et al. Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29042451 DOI: 10.1096/Fj.201700555R  0.306
2017 Ojiaku CA, Cao G, Zhu W, Yoo EJ, Shumyatcher M, Himes BE, An SS, Panettieri RA. TGF-β1 Evokes Human Airway Smooth Muscle Cell Shortening and Hyperresponsiveness via Smad3. American Journal of Respiratory Cell and Molecular Biology. PMID 28984468 DOI: 10.1165/Rcmb.2017-0247Oc  0.36
2017 Yoo EJ, Cao G, Koziol-White CJ, Ojiaku CA, Sunder K, Jude JA, Michael JV, Lam H, Pushkarsky I, Damoiseaux R, Di Carlo D, Ahn K, An SS, Penn RB, Panettieri RA. Gα12 Facilitates Carbachol-Induced Shortening in Human Airway Smooth Muscle By Modulating Phosphoinositide 3-Kinase-Mediated Activation In A RhoA-Dependent Manner. British Journal of Pharmacology. PMID 28921504 DOI: 10.1111/Bph.14040  0.375
2017 Barreto Ortiz S, Hori D, Nomura Y, Yun X, Jiang H, Yong H, Chen J, Paek S, Pandey D, Sikka G, Bhatta A, Gillard A, Steppan J, Kim JH, Adachi H, ... ... An SS, et al. Opsin 3 and 4 Mediate Light-Induced Pulmonary Vasorelaxation that is Potentiated by G-Protein Receptor Kinase 2 Inhibition. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00091.2017. PMID 28882814 DOI: 10.1152/Ajplung.00091.2017  0.332
2017 Haffner MC, Esopi DM, Chaux A, Gürel M, Ghosh S, Vaghasia AM, Tsai H, Kim K, Castagna N, Lam H, Hicks J, Wyhs N, Biswal Shinohara D, Hurley PJ, Simons BW, ... ... An SS, et al. AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination. Nature Communications. 8: 142. PMID 28747635 DOI: 10.1038/S41467-017-00084-8  0.348
2017 An SS, Liggett SB. Taste and smell GPCRs in the lung: Evidence for a previously unrecognized widespread chemosensory system. Cellular Signalling. PMID 28167233 DOI: 10.1016/J.Cellsig.2017.02.002  0.389
2017 Steppan J, Bergman Y, Viegas K, Armstrong D, Tan S, Wang H, Melucci S, Hori D, Park SY, Barreto SF, Isak A, Jandu S, Flavahan N, Butlin M, An SS, et al. Tissue Transglutaminase Modulates Vascular Stiffness and Function Through Crosslinking-Dependent and Crosslinking-Independent Functions. Journal of the American Heart Association. 6. PMID 28159817 DOI: 10.1161/Jaha.116.004161  0.352
2017 Kim D, Woo JA, Geffken E, An SS, Liggett SB. Coupling of Airway Smooth Muscle TAS2Rs to Intracellular Signaling and Relaxation is via Gαi1,2,3. American Journal of Respiratory Cell and Molecular Biology. PMID 28145731 DOI: 10.1165/Rcmb.2016-0373Oc  0.367
2017 Mikami M, Zhang Y, Danielsson J, Joell T, Yong HM, Townsend E, Khurana S, An SS, Emala CW. Impaired Relaxation of Airway Smooth Muscle in Mice Lacking the Actin Binding Protein Gelsolin. American Journal of Respiratory Cell and Molecular Biology. PMID 28118027 DOI: 10.1165/Rcmb.2016-0292Oc  0.399
2016 Aisenberg WH, Huang J, Zhu W, Rajkumar P, Cruz R, Santhanam L, Natarajan N, Yong HM, De Santiago B, Oh JJ, Yoon AR, Panettieri RA, Homann O, Sullivan JK, Liggett SB, ... ... An SS, et al. Defining an olfactory receptor function in airway smooth muscle cells. Scientific Reports. 6: 38231. PMID 27905542 DOI: 10.1038/Srep38231  0.399
2016 Kim D, Pauer SH, Yong HM, An SS, Liggett SB. β2-adrenergic Receptors Chaperone Trapped Bitter Taste Receptor 14 to the Cell Surface as a Heterodimer and Exert Unidirectional Desensitization of Taste Receptor Function. The Journal of Biological Chemistry. PMID 27342779 DOI: 10.1074/Jbc.M116.722736  0.333
2016 Park J, Kim DH, Kim HN, Wang CJ, Kwak MK, Hur E, Suh KY, An SS, Levchenko A. Directed migration of cancer cells by the graded texture of the underlying matrix. Nature Materials. PMID 26974411 DOI: 10.1038/Nmat4586  0.353
2016 An SS, Mitzner W, Tang WY, Ahn K, Yoon AR, Huang J, Kilic O, Yong HM, Fahey JW, Kumar S, Biswal S, Holgate ST, Panettieri RA, Solway J, Liggett SB. An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma. The Journal of Allergy and Clinical Immunology. PMID 26936804 DOI: 10.1016/J.Jaci.2015.12.1315  0.344
2015 Aifuwa I, Giri A, Longe N, Lee SH, An SS, Wirtz D. Senescent stromal cells induce cancer cell migration via inhibition of RhoA/ROCK/myosin-based cell contractility. Oncotarget. 6: 30516-31. PMID 26483365 DOI: 10.18632/Oncotarget.5854  0.355
2015 Hurley PJ, Hughes RM, Simons B, Huang J, Miller RM, Shinder B, Haffner MC, Esopi D, Kinura Y, Jabbari J, Ross AE, Erho N, Vergara IA, Faraj SF, Davicioni E, ... ... An S, et al. Androgen Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression. Cancer Research. PMID 26294211 DOI: 10.1158/0008-5472.Can-15-0024  0.326
2015 Camoretti-Mercado B, Pauer SH, Yong HM, Smith DC, Deshpande DA, An SS, Liggett SB. Pleiotropic Effects of Bitter Taste Receptors on [Ca2+]i Mobilization, Hyperpolarization, and Relaxation of Human Airway Smooth Muscle Cells. Plos One. 10: e0131582. PMID 26121686 DOI: 10.1371/Journal.Pone.0131582  0.333
2015 Yoon AR, Stasinopoulos I, Kim JH, Yong HM, Kilic O, Wirtz D, Bhujwalla ZM, An SS. COX-2 dependent regulation of mechanotransduction in human breast cancer cells. Cancer Biology & Therapy. 16: 430-7. PMID 25701047 DOI: 10.1080/15384047.2014.1003004  0.363
2015 Gajula RP, Chettiar ST, Williams RD, Nugent K, Kato Y, Wang H, Malek R, Taparra K, Cades J, Annadanam A, Yoon AR, Fertig E, Firulli BA, Mazzacurati L, Burns TF, ... ... An SS, et al. Structure-function studies of the bHLH phosphorylation domain of TWIST1 in prostate cancer cells. Neoplasia (New York, N.Y.). 17: 16-31. PMID 25622896 DOI: 10.1016/J.Neo.2014.10.009  0.322
2015 Moon YW, Rao G, Kim JJ, Shim HS, Park KS, An SS, Kim B, Steeg PS, Sarfaraz S, Changwoo Lee L, Voeller D, Choi EY, Luo J, Palmieri D, Chung HC, et al. LAMC2 enhances the metastatic potential of lung adenocarcinoma. Cell Death and Differentiation. 22: 1341-52. PMID 25591736 DOI: 10.1038/Cdd.2014.228  0.306
2015 Shiraishi T, Verdone JE, Huang J, Kahlert UD, Hernandez JR, Torga G, Zarif JC, Epstein T, Gatenby R, McCartney A, Elisseeff JH, Mooney SM, An SS, Pienta KJ. Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells. Oncotarget. 6: 130-43. PMID 25426557 DOI: 10.18632/Oncotarget.2766  0.336
2014 Wang WC, Pauer SH, Smith DC, Dixon MA, Disimile DJ, Panebra A, An SS, Camoretti-Mercado B, Liggett SB. Targeted transgenesis identifies Gαs as the bottleneck in β2-adrenergic receptor cell signaling and physiological function in airway smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 307: L775-80. PMID 25260754 DOI: 10.1152/Ajplung.00209.2014  0.362
2014 Morgan SJ, Deshpande DA, Tiegs BC, Misior AM, Yan H, Hershfeld AV, Rich TC, Panettieri RA, An SS, Penn RB. β-Agonist-mediated relaxation of airway smooth muscle is protein kinase A-dependent. The Journal of Biological Chemistry. 289: 23065-74. PMID 24973219 DOI: 10.1074/Jbc.M114.557652  0.372
2014 Fitzgerald R, DeSantiago B, Lee DY, Yang G, Kim JY, Foster DB, Chan-Li Y, Horton MR, Panettieri RA, Wang R, An SS. H2S relaxes isolated human airway smooth muscle cells via the sarcolemmal K(ATP) channel. Biochemical and Biophysical Research Communications. 446: 393-8. PMID 24613832 DOI: 10.1016/J.Bbrc.2014.02.129  0.347
2014 Robinett KS, Koziol-White CJ, Akoluk A, An SS, Panettieri RA, Liggett SB. Bitter taste receptor function in asthmatic and nonasthmatic human airway smooth muscle cells. American Journal of Respiratory Cell and Molecular Biology. 50: 678-83. PMID 24219573 DOI: 10.1165/Rcmb.2013-0439Rc  0.403
2013 Gajula RP, Chettiar ST, Williams RD, Thiyagarajan S, Kato Y, Aziz K, Wang R, Gandhi N, Wild AT, Vesuna F, Ma J, Salih T, Cades J, Fertig E, Biswal S, ... ... An SS, et al. The twist box domain is required for Twist1-induced prostate cancer metastasis. Molecular Cancer Research : McR. 11: 1387-400. PMID 23982216 DOI: 10.1158/1541-7786.Mcr-13-0218-T  0.343
2013 Jung SM, Jandu S, Steppan J, Belkin A, An SS, Pak A, Choi EY, Nyhan D, Butlin M, Viegas K, Avolio A, Berkowitz DE, Santhanam L. Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice. American Journal of Physiology. Heart and Circulatory Physiology. 305: H803-10. PMID 23873798 DOI: 10.1152/Ajpheart.00103.2013  0.655
2013 Kim JJ, Yin B, Christudass CS, Terada N, Rajagopalan K, Fabry B, Lee DY, Shiraishi T, Getzenberg RH, Veltri RW, An SS, Mooney SM. Acquisition of paclitaxel resistance is associated with a more aggressive and invasive phenotype in prostate cancer. Journal of Cellular Biochemistry. 114: 1286-93. PMID 23192682 DOI: 10.1002/Jcb.24464  0.302
2013 Gajula R, Chettiar S, Williams R, Thiyagarajan S, Aziz K, Gandhi N, Wild A, Salih T, Kato Y, Cades J, Fertig E, Chung C, Herman J, Hales R, Rudin C, ... An S, et al. Abstract B45: The Twist box domain is required for Twist1-induced metastasis of prostate cancer cells Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-B45  0.359
2013 Gajula RP, Chettiar ST, Williams RD, Thiyagarajan S, Kato Y, Aziz K, Wang R, Gandhi N, Wild AT, Vesuna F, Ma J, Salih T, Cades J, Fertig E, Biswal S, ... ... An S, et al. Abstract 1493: The Twist box is required for Twist1-induced prostate cancer metastasis. Cancer Research. 73: 1493-1493. DOI: 10.1158/1538-7445.Am2013-1493  0.357
2013 Yoon AR, Stasinopoulos I, An S, Bhujwalla ZM. Abstract 1098: Mechano-molecular imaging of the role of COX-2 in cell traction force. Cancer Research. 73: 1098-1098. DOI: 10.1158/1538-7445.Am2013-1098  0.355
2012 An SS, Wang WC, Koziol-White CJ, Ahn K, Lee DY, Kurten RC, Panettieri RA, Liggett SB. TAS2R activation promotes airway smooth muscle relaxation despite β(2)-adrenergic receptor tachyphylaxis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 303: L304-11. PMID 22683571 DOI: 10.1152/Ajplung.00126.2012  0.351
2012 Garzon-Muvdi T, Schiapparelli P, ap Rhys C, Guerrero-Cazares H, Smith C, Kim DH, Kone L, Farber H, Lee DY, An SS, Levchenko A, Quiñones-Hinojosa A. Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation. Plos Biology. 10: e1001320. PMID 22570591 DOI: 10.1371/Journal.Pbio.1001320  0.363
2012 Saxena H, Deshpande DA, Tiegs BC, Yan H, Battafarano RJ, Burrows WM, Damera G, Panettieri RA, Dubose TD, An SS, Penn RB. The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH British Journal of Pharmacology. 166: 981-990. PMID 22145625 DOI: 10.1111/J.1476-5381.2011.01807.X  0.334
2011 Deshpande DA, Robinett KS, Wang WC, Sham JS, An SS, Liggett SB. Bronchodilator activity of bitter tastants in human tissue. Nature Medicine. 17: 776-8. PMID 21738150 DOI: 10.1038/Nm0711-776B  0.347
2011 An SS, Askovich PS, Zarembinski TI, Ahn K, Peltier JM, von Rechenberg M, Sahasrabudhe S, Fredberg JJ. A novel small molecule target in human airway smooth muscle for potential treatment of obstructive lung diseases: a staged high-throughput biophysical screening. Respiratory Research. 12: 8. PMID 21232113 DOI: 10.1186/1465-9921-12-8  0.321
2010 Deshpande DA, Wang WC, McIlmoyle EL, Robinett KS, Schillinger RM, An SS, Sham JS, Liggett SB. Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction. Nature Medicine. 16: 1299-304. PMID 20972434 DOI: 10.1038/Nm.2237  0.374
2010 Pechkovsky DV, Hackett TL, An SS, Shaheen F, Murray LA, Knight DA. Human lung parenchyma but not proximal bronchi produces fibroblasts with enhanced TGF-beta signaling and alpha-SMA expression. American Journal of Respiratory Cell and Molecular Biology. 43: 641-51. PMID 20061511 DOI: 10.1165/Rcmb.2009-0318Oc  0.32
2009 An SS, Kim J, Ahn K, Trepat X, Drake KJ, Kumar S, Ling G, Purington C, Rangasamy T, Kensler TW, Mitzner W, Fredberg JJ, Biswal S. Cell stiffness, contractile stress and the role of extracellular matrix. Biochemical and Biophysical Research Communications. 382: 697-703. PMID 19327344 DOI: 10.1016/J.Bbrc.2009.03.118  0.396
2007 Trepat X, Deng L, An SS, Navajas D, Tschumperlin DJ, Gerthoffer WT, Butler JP, Fredberg JJ. Universal physical responses to stretch in the living cell. Nature. 447: 592-5. PMID 17538621 DOI: 10.1038/Nature05824  0.32
2007 An SS, Bai TR, Bates JH, Black JL, Brown RH, Brusasco V, Chitano P, Deng L, Dowell M, Eidelman DH, Fabry B, Fairbank NJ, Ford LE, Fredberg JJ, Gerthoffer WT, et al. Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. The European Respiratory Journal. 29: 834-60. PMID 17470619 DOI: 10.1183/09031936.00112606  0.331
2006 An SS, Fabry B, Trepat X, Wang N, Fredberg JJ. Do biophysical properties of the airway smooth muscle in culture predict airway hyperresponsiveness? American Journal of Respiratory Cell and Molecular Biology. 35: 55-64. PMID 16484685 DOI: 10.1165/Rcmb.2005-0453Oc  0.391
2006 Ratnovsky A, An S, Mellema M, Shore S, Fredberg J. Mechanics and remodeling of the airway smooth muscle cell: effects of adipose hormones Journal of Biomechanics. 39: S582-S583. DOI: 10.1016/S0021-9290(06)85411-4  0.389
2005 Laudadio RE, Millet EJ, Fabry B, An SS, Butler JP, Fredberg JJ. Rat airway smooth muscle cell during actin modulation: rheology and glassy dynamics. American Journal of Physiology. Cell Physiology. 289: C1388-95. PMID 16120653 DOI: 10.1152/Ajpcell.00060.2005  0.373
2005 An SS, Pennella CM, Gonnabathula A, Chen J, Wang N, Gaestel M, Hassoun PM, Fredberg JJ, Kayyali US. Hypoxia alters biophysical properties of endothelial cells via p38 MAPK- and Rho kinase-dependent pathways. American Journal of Physiology. Cell Physiology. 289: C521-30. PMID 15857906 DOI: 10.1152/Ajpcell.00429.2004  0.381
2004 An SS, Fabry B, Mellema M, Bursac P, Gerthoffer WT, Kayyali US, Gaestel M, Shore SA, Fredberg JJ. Role of heat shock protein 27 in cytoskeletal remodeling of the airway smooth muscle cell. Journal of Applied Physiology (Bethesda, Md. : 1985). 96: 1701-13. PMID 14729728 DOI: 10.1152/Japplphysiol.01129.2003  0.325
2002 An SS, Laudadio RE, Lai J, Rogers RA, Fredberg JJ. Stiffness changes in cultured airway smooth muscle cells. American Journal of Physiology. Cell Physiology. 283: C792-801. PMID 12176736 DOI: 10.1152/Ajpcell.00425.2001  0.353
2000 An SS, Hai CM. Mechanical signals and mechanosensitive modulation of intracellular [Ca(2+)] in smooth muscle. American Journal of Physiology. Cell Physiology. 279: C1375-84. PMID 11029285 DOI: 10.1152/Ajpcell.2000.279.5.C1375  0.532
1999 An SS, Hai CM. Mechanical strain modulates maximal phosphatidylinositol turnover in airway smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 277: L968-L974. PMID 29592323 DOI: 10.1152/ajplung.1999.277.5.L968  0.546
1999 An SS, Hai CM. Mechanical strain modulates maximal phosphatidylinositol turnover in airway smooth muscle. The American Journal of Physiology. 277: L968-74. PMID 10564182 DOI: 10.1152/Ajplung.1999.277.5.L968  0.579
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