Rizwan Haq, Ph.D. - Publications

Affiliations: 
2003 University of Toronto, Toronto, ON, Canada 
Area:
Neuroscience Biology, Molecular Biology, Animal Physiology Biology

15/38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Lauss M, Haq R, Cirenajwis H, Phung B, Harbst K, Staaf J, Rosengren F, Holm K, Aine M, Jirström K, Borg Å, Busch C, Geisler J, Lønning PE, Ringnér M, et al. Genome-Wide DNA Methylation Analysis in Melanoma Reveals the Importance of CpG Methylation in MITF Regulation. The Journal of Investigative Dermatology. 135: 1820-8. PMID 25705847 DOI: 10.1038/jid.2015.61  0.36
2014 Frederick DT, Salas Fragomeni RA, Schalck A, Ferreiro-Neira I, Hoff T, Cooper ZA, Haq R, Panka DJ, Kwong LN, Davies MA, Cusack JC, Flaherty KT, Fisher DE, Mier JW, Wargo JA, et al. Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics. Plos One. 9: e101286. PMID 24983357 DOI: 10.1371/journal.pone.0101286  0.36
2014 Konieczkowski DJ, Johannessen CM, Abudayyeh O, Kim JW, Cooper ZA, Piris A, Frederick DT, Barzily-Rokni M, Straussman R, Haq R, Fisher DE, Mesirov JP, Hahn WC, Flaherty KT, Wargo JA, et al. A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors. Cancer Discovery. 4: 816-27. PMID 24771846 DOI: 10.1158/2159-8290.CD-13-0424  0.36
2013 Haq R, Shoag J, Andreu-Perez P, Yokoyama S, Edelman H, Rowe GC, Frederick DT, Hurley AD, Nellore A, Kung AL, Wargo JA, Song JS, Fisher DE, Arany Z, Widlund HR. Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF. Cancer Cell. 23: 302-15. PMID 23477830 DOI: 10.1016/j.ccr.2013.02.003  0.36
2013 Haq R, Yokoyama S, Hawryluk EB, Jönsson GB, Frederick DT, McHenry K, Porter D, Tran TN, Love KT, Langer R, Anderson DG, Garraway LA, Duncan LM, Morton DL, Hoon DS, et al. BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition. Proceedings of the National Academy of Sciences of the United States of America. 110: 4321-6. PMID 23447565 DOI: 10.1073/pnas.1205575110  0.36
2013 Shoag J, Haq R, Zhang M, Liu L, Rowe GC, Jiang A, Koulisis N, Farrel C, Amos CI, Wei Q, Lee JE, Zhang J, Kupper TS, Qureshi AA, Cui R, et al. PGC-1 coactivators regulate MITF and the tanning response. Molecular Cell. 49: 145-57. PMID 23201126 DOI: 10.1016/j.molcel.2012.10.027  0.36
2012 Li J, Song JS, Bell RJ, Tran TN, Haq R, Liu H, Love KT, Langer R, Anderson DG, Larue L, Fisher DE. YY1 regulates melanocyte development and function by cooperating with MITF. Plos Genetics. 8: e1002688. PMID 22570637 DOI: 10.1371/journal.pgen.1002688  0.36
2011 Yokoyama S, Woods SL, Boyle GM, Aoude LG, MacGregor S, Zismann V, Gartside M, Cust AE, Haq R, Harland M, Taylor JC, Duffy DL, Holohan K, Dutton-Regester K, Palmer JM, et al. A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature. 480: 99-103. PMID 22080950 DOI: 10.1038/nature10630  0.36
2002 Haq R, Brenton JD, Takahashi M, Finan D, Finkielsztein A, Damaraju S, Rottapel R, Zanke B. Constitutive p38HOG mitogen-activated protein kinase activation induces permanent cell cycle arrest and senescence. Cancer Research. 62: 5076-82. PMID 12208764  0.36
2002 Ho JM, Nguyen MH, Dierov JK, Badger KM, Beattie BK, Tartaro P, Haq R, Zanke BW, Carroll MP, Barber DL. TEL-JAK2 constitutively activates the extracellular signal-regulated kinase (ERK), stress-activated protein/Jun kinase (SAPK/JNK), and p38 signaling pathways. Blood. 100: 1438-48. PMID 12149229  0.36
2002 Haq R, Halupa A, Beattie BK, Mason JM, Zanke BW, Barber DL. Regulation of erythropoietin-induced STAT serine phosphorylation by distinct mitogen-activated protein kinases. The Journal of Biological Chemistry. 277: 17359-66. PMID 11875080 DOI: 10.1074/jbc.M201842200  0.36
2001 Haq R, Randall S, Midmer M, Yee K, Zanke B. NKIATRE is a novel conserved cdc2-related kinase. Genomics. 71: 131-41. PMID 11161806 DOI: 10.1006/geno.2000.6424  0.36
2000 Jones NL, Islur A, Haq R, Mascarenhas M, Karmali MA, Perdue MH, Zanke BW, Sherman PM. Escherichia coli Shiga toxins induce apoptosis in epithelial cells that is regulated by the Bcl-2 family. American Journal of Physiology. Gastrointestinal and Liver Physiology. 278: G811-9. PMID 10801274  0.36
1999 Midmer M, Haq R, Squire JA, Zanke BW. Identification of NKIAMRE, the human homologue to the mitogen-activated protein kinase-/cyclin-dependent kinase-related protein kinase NKIATRE, and its loss in leukemic blasts with chromosome arm 5q deletion Cancer Research. 59: 4069-4074. PMID 10463609  0.36
1998 Haq R, Zanke B. Inhibition of apoptotic signaling pathways in cancer cells as a mechanism of chemotherapy resistance. Cancer Metastasis Reviews. 17: 233-9. PMID 9770120 DOI: 10.1023/A:1006075007857  0.36
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2019 Montero J, Gstalder C, Kim DJ, Sadowicz D, Miles W, Manos M, Cidado JR, Paul Secrist J, Tron AE, Flaherty K, Stephen Hodi F, Yoon CH, Letai A, Fisher DE, Haq R. Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies. Nature Communications. 10: 5157. PMID 31727958 DOI: 10.1038/s41467-019-12477-y  0.01
2019 Naik GS, Waikar SS, Johnson AEW, Buchbinder EI, Haq R, Hodi FS, Schoenfeld JD, Ott PA. Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibition. Journal For Immunotherapy of Cancer. 7: 89. PMID 30922394 DOI: 10.1186/s40425-019-0512-5  0.01
2018 Jerby-Arnon L, Shah P, Cuoco MS, Rodman C, Su MJ, Melms JC, Leeson R, Kanodia A, Mei S, Lin JR, Wang S, Rabasha B, Liu D, Zhang G, Margolais C, ... ... Haq R, et al. A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade. Cell. 175: 984-997.e24. PMID 30388455 DOI: 10.1016/j.cell.2018.09.006  0.01
2018 Miao D, Margolis CA, Vokes NI, Liu D, Taylor-Weiner A, Wankowicz SM, Adeegbe D, Keliher D, Schilling B, Tracy A, Manos M, Chau NG, Hanna GJ, Polak P, Rodig SJ, ... ... Haq R, et al. Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors. Nature Genetics. PMID 30150660 DOI: 10.1038/s41588-018-0200-2  0.01
2018 Berndt N, Rösner J, Haq RU, Kann O, Kovács R, Holzhütter HG, Spies C, Liotta A. Possible neurotoxicity of the anesthetic propofol: evidence for the inhibition of complex II of the respiratory chain in area CA3 of rat hippocampal slices. Archives of Toxicology. PMID 30143847 DOI: 10.1007/s00204-018-2295-8  0.01
2017 Haq R. Trapping Cancers as They Adapt to Survive. Cancer Discovery. 7: 1216-1217. PMID 29097618 DOI: 10.1158/2159-8290.CD-17-0976  0.01
2017 Lee H, Hodi FS, Giobbie-Hurder A, Ott PA, Buchbinder EI, Haq R, Tolaney S, Barroso-Sousa R, Zhang K, Donahue H, Davis M, Gargano ME, Kelley KM, Carroll RS, Kaiser UB, et al. Characterization of Thyroid Disorders in Patients Receiving Immune Checkpoint Inhibition Therapy. Cancer Immunology Research. PMID 29079654 DOI: 10.1158/2326-6066.CIR-17-0208  0.01
2017 Wang DY, Eroglu Z, Ozgun A, Leger PD, Zhao S, Ye F, Luke JJ, Joseph RW, Haq R, Ott PA, Hodi FS, Sosman J, Johnson DB, Buchbinder EL. Clinical features of acquired resistance to anti-PD-1 therapy in advanced melanoma. Cancer Immunology Research. PMID 28396509 DOI: 10.1158/2326-6066.CIR-16-0287  0.01
2016 Gee MS, Ghazani AA, Haq R, Wargo JA, Sebas M, Sullivan RJ, Lee H, Weissleder R. Point of care assessment of melanoma tumor signaling and metastatic burden from μNMR analysis of tumor fine needle aspirates and peripheral blood. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 27993725 DOI: 10.1016/j.nano.2016.12.006  0.01
2014 Bhavsar B, Choksi B, Sanmukhani J, Dogra A, Haq R, Mehta S, Mukherjee S, Subramanian V, Sheikh S, Mittal R. Clindamycin 1% Nano-emulsion Gel Formulation for the Treatment of Acne Vulgaris: Results of a Randomized, Active Controlled, Multicentre, Phase IV Clinical Trial. Journal of Clinical and Diagnostic Research : Jcdr. 8: YC05-9. PMID 25302253 DOI: 10.7860/JCDR/2014/9111.4769  0.01
2014 Haq R, Flaherty K. The melanoma metastasis X-factor. Pigment Cell & Melanoma Research. 27: 698. PMID 24953382 DOI: 10.1111/pcmr.12285  0.01
2014 Hollnagel JO, Maslarova A, Haq RU, Heinemann U. GABAB receptor dependent modulation of sharp wave-ripple complexes in the rat hippocampus in vitro. Neuroscience Letters. 574: 15-20. PMID 24796812 DOI: 10.1016/j.neulet.2014.04.045  0.01
2014 Haq R. Metabolic dysregulation in melanoma: cause or consequence? Cancer Discovery. 4: 390-1. PMID 24706656 DOI: 10.1158/2159-8290.CD-14-0173  0.01
2014 Haq R, Fisher DE, Widlund HR. Molecular pathways: BRAF induces bioenergetic adaptation by attenuating oxidative phosphorylation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 2257-63. PMID 24610826 DOI: 10.1158/1078-0432.CCR-13-0898  0.01
2013 Haq R, Fisher DE. Improving apoptotic responses to targeted therapy. Oncotarget. 4: 1331. PMID 23934756  0.01
2013 Haq R, Fisher DE. Targeting melanoma by small molecules: challenges ahead. Pigment Cell & Melanoma Research. 26: 464-9. PMID 23611259 DOI: 10.1111/pcmr.12109  0.01
2011 Haq R, Fisher DE. Biology and clinical relevance of the micropthalmia family of transcription factors in human cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 3474-82. PMID 21670463 DOI: 10.1200/JCO.2010.32.6223  0.01
2011 Haq Ru, Farooq U, Wahab A, Raza M, Ahmad VU, Khan RA. Investigation of antitussive and toxicological activity of Ballota limbata in mice. Pharmaceutical Biology. 49: 627-32. PMID 21554006 DOI: 10.3109/13880209.2011.563317  0.01
2009 Wójtowicz AM, van den Boom L, Chakrabarty A, Maggio N, Haq RU, Behrens CJ, Heinemann U. Monoamines block kainate- and carbachol-induced gamma-oscillations but augment stimulus-induced gamma-oscillations in rat hippocampus in vitro. Hippocampus. 19: 273-88. PMID 19173289 DOI: 10.1002/hipo.20508  0.01
2006 Prutkin JM, Haq R. A dish best served hot. The American Journal of Medicine. 119: 307-9. PMID 16564770 DOI: 10.1016/j.amjmed.2005.07.030  0.01
2006 McGill GG, Haq R, Nishimura EK, Fisher DE. c-Met expression is regulated by Mitf in the melanocyte lineage. The Journal of Biological Chemistry. 281: 10365-73. PMID 16455654 DOI: 10.1074/jbc.M513094200  0.01
2003 Haq R. Age-old theories die hard. Clinical and Investigative Medicine. MéDecine Clinique Et Experimentale. 26: 116-20. PMID 12858945  0.01
2003 Haq RU, Pendlebury WW, Fries TJ, Tandan R. Chronic inflammatory demyelinating polyradiculoneuropathy in diabetic patients. Muscle & Nerve. 27: 465-70. PMID 12661048 DOI: 10.1002/mus.1250  0.01
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