| Year |
Citation |
Score |
| 2023 |
Eyford BA, Lazarczyk MJ, Choi KB, Varghese M, Arora H, Kari S, Munro L, Pfeifer CG, Sowa A, Dickstein DR, Dickstein DL, Jefferies WA. Outside-in signaling through the major histocompatibility complex class-I cytoplasmic tail modulates glutamate receptor expression in neurons. Scientific Reports. 13: 13079. PMID 37567897 DOI: 10.1038/s41598-023-38663-z |
0.733 |
|
| 2023 |
Lazarczyk MJ, Eyford BA, Varghese M, Arora H, Munro L, Warda T, Pfeifer CG, Sowa A, Dickstein DR, Rumbell T, Jefferies WA, Dickstein DL. The intracellular domain of major histocompatibility class-I proteins is essential for maintaining excitatory spine density and synaptic ultrastructure in the brain. Scientific Reports. 13: 6448. PMID 37081001 DOI: 10.1038/s41598-023-30054-8 |
0.74 |
|
| 2019 |
Fenninger F, Han J, Stanwood SR, Nohara LL, Arora H, Choi KB, Munro L, Pfeifer CG, Shanina I, Horwitz MS, Jefferies WA. Mutation of an L-Type Calcium Channel Gene Leads to T Lymphocyte Dysfunction. Frontiers in Immunology. 10: 2473. PMID 31736943 DOI: 10.3389/Fimmu.2019.02473 |
0.322 |
|
| 2018 |
Hur WS, Mazinani N, Lu XJD, Yefet LS, Byrnes JR, Ho L, Yeon JH, Filipenko S, Wolberg AS, Jefferies WA, Kastrup CJ. Coagulation factor XIIIa crosslinks amyloid b into dimers and oligomers and to blood proteins. The Journal of Biological Chemistry. PMID 30409906 DOI: 10.1074/Jbc.Ra118.005352 |
0.304 |
|
| 2018 |
Singh CSB, Jefferies WA. P3-206: Attuning Cerebral Vessel Growth In The Alzheimer'S Brain As A Therapeutic Intervention Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1565 |
0.31 |
|
| 2016 |
Lazarczyk MJ, Kemmler JE, Eyford BA, Short JA, Varghese M, Sowa A, Dickstein DR, Yuk FJ, Puri R, Biron KE, Leist M, Jefferies WA, Dickstein DL. Major Histocompatibility Complex class I proteins are critical for maintaining neuronal structural complexity in the aging brain. Scientific Reports. 6: 26199. PMID 27229916 DOI: 10.1038/Srep26199 |
0.741 |
|
| 2015 |
Nohara LL, Stanwood SR, Omilusik KD, Jefferies WA. Tweeters, Woofers and Horns: The Complex Orchestration of Calcium Currents in T Lymphocytes. Frontiers in Immunology. 6: 234. PMID 26052328 DOI: 10.3389/Fimmu.2015.00234 |
0.3 |
|
| 2014 |
Gabathuler R, Vitalis TZ, Nounou MI, Adkins CE, Lockman PR, Jefferies WA. Abstract 642: Transcend, a protein vector for brain delivery, allows trastuzumab to reach the brain at effective concentration after incorporation to form BT2111 Cancer Research. 74: 642-642. DOI: 10.1158/1538-7445.Am2014-642 |
0.346 |
|
| 2014 |
Vitalis T, Jefferies W, Gabathuler R. Abstract 2905: The activity of a new class of biologics: trastuzumab conjugates designed to treat brain metastases of HER2+ breast cancers Cancer Research. 74: 2905-2905. DOI: 10.1158/1538-7445.Am2014-2905 |
0.322 |
|
| 2013 |
Jefferies WA, Price KA, Biron KE, Fenninger F, Pfeifer CG, Dickstein DL. Adjusting the compass: new insights into the role of angiogenesis in Alzheimer's disease. Alzheimer's Research & Therapy. 5: 64. PMID 24351529 DOI: 10.1186/Alzrt230 |
0.648 |
|
| 2013 |
Omilusik KD, Nohara LL, Stanwood S, Jefferies WA. Weft, warp, and weave: the intricate tapestry of calcium channels regulating T lymphocyte function. Frontiers in Immunology. 4: 164. PMID 23805141 DOI: 10.3389/Fimmu.2013.00164 |
0.301 |
|
| 2013 |
Biron KE, Dickstein DL, Gopaul R, Fenninger F, Jefferies WA. Cessation of neoangiogenesis in Alzheimer's disease follows amyloid-beta immunization. Scientific Reports. 3: 1354. PMID 23446889 DOI: 10.1038/Srep01354 |
0.651 |
|
| 2013 |
Gabathuler R, Vitalis TZ, Nounou MI, Iqbal U, Moreno M, Adkins CE, Torrell TO, Jefferies WA, Lockman PR. Abstract A247: BT2111, a new anticancer agent composed of trastuzumab and transcend a vector for brain delivery for the treatment of metastatic Her2+ breast cancer. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A247 |
0.329 |
|
| 2012 |
Basha G, Omilusik K, Chavez-Steenbock A, Reinicke AT, Lack N, Choi KB, Jefferies WA. A CD74-dependent MHC class I endolysosomal cross-presentation pathway. Nature Immunology. 13: 237-45. PMID 22306692 DOI: 10.1038/Ni.2225 |
0.305 |
|
| 2011 |
Biron KE, Dickstein DL, Gopaul R, Jefferies WA. Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease. Plos One. 6: e23789. PMID 21909359 DOI: 10.1371/Journal.Pone.0023789 |
0.66 |
|
| 2011 |
Omilusik K, Priatel JJ, Chen X, Wang YT, Xu H, Choi KB, Gopaul R, McIntyre-Smith A, Teh HS, Tan R, Bech-Hansen NT, Waterfield D, Fedida D, Hunt SV, Jefferies WA. The Ca(v)1.4 calcium channel is a critical regulator of T cell receptor signaling and naive T cell homeostasis. Immunity. 35: 349-60. PMID 21835646 DOI: 10.1016/J.Immuni.2011.07.011 |
0.321 |
|
| 2010 |
Bennett J, Basivireddy J, Kollar A, Biron KE, Reickmann P, Jefferies WA, McQuaid S. Blood-brain barrier disruption and enhanced vascular permeability in the multiple sclerosis model EAE. Journal of Neuroimmunology. 229: 180-91. PMID 20832870 DOI: 10.1016/J.Jneuroim.2010.08.011 |
0.312 |
|
| 2009 |
Reinicke AT, Omilusik KD, Basha G, Jefferies WA. Dendritic cell cross-priming is essential for immune responses to Listeria monocytogenes. Plos One. 4: e7210. PMID 19806187 DOI: 10.1371/Journal.Pone.0007210 |
0.329 |
|
| 2009 |
Kennard ML, Shimizu KY, Gabathuler R, Rothenberger S, Theilmann D, Jefferies WA. Expression of cell surface GPI-anchored human p97 in baculovirus-infected insect cells. Biotechnology and Bioengineering. 55: 41-53. PMID 18636443 DOI: 10.1002/(Sici)1097-0290(19970705)55:1<41::Aid-Bit6>3.0.Co;2-X |
0.327 |
|
| 2008 |
Setiadi AF, Omilusik K, David MD, Seipp RP, Hartikainen J, Gopaul R, Choi KB, Jefferies WA. Epigenetic enhancement of antigen processing and presentation promotes immune recognition of tumors. Cancer Research. 68: 9601-7. PMID 19047136 DOI: 10.1158/0008-5472.Can-07-5270 |
0.305 |
|
| 2008 |
Basha G, Lizée G, Reinicke AT, Seipp RP, Omilusik KD, Jefferies WA. MHC class I endosomal and lysosomal trafficking coincides with exogenous antigen loading in dendritic cells. Plos One. 3: e3247. PMID 18802471 DOI: 10.1371/Journal.Pone.0003247 |
0.605 |
|
| 2008 |
Zhang QJ, Li XL, Wang D, Huang XC, Mathis JM, Duan WM, Knight D, Shi R, Glass J, Zhang DQ, Eisenbach L, Jefferies WA. Trogocytosis of MHC-I/peptide complexes derived from tumors and infected cells enhances dendritic cell cross-priming and promotes adaptive T cell responses. Plos One. 3: e3097. PMID 18769733 DOI: 10.1371/Journal.Pone.0003097 |
0.356 |
|
| 2008 |
Karkan D, Pfeifer C, Vitalis TZ, Arthur G, Ujiie M, Chen Q, Tsai S, Koliatis G, Gabathuler R, Jefferies WA. A unique carrier for delivery of therapeutic compounds beyond the blood-brain barrier. Plos One. 3: e2469. PMID 18575595 DOI: 10.1371/Journal.Pone.0002469 |
0.347 |
|
| 2008 |
Lou Y, Basha G, Seipp RP, Cai B, Chen SS, Moise AR, Jeffries AP, Gopaul RS, Vitalis TZ, Jefferies WA. Combining the antigen processing components TAP and Tapasin elicits enhanced tumor-free survival. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 1494-501. PMID 18316574 DOI: 10.1158/1078-0432.Ccr-07-1066 |
0.324 |
|
| 2007 |
Zhang QJ, Seipp RP, Chen SS, Vitalis TZ, Li XL, Choi KB, Jeffries A, Jefferies WA. TAP expression reduces IL-10 expressing tumor infiltrating lymphocytes and restores immunosurveillance against melanoma. International Journal of Cancer. 120: 1935-41. PMID 17278102 DOI: 10.1002/Ijc.22371 |
0.323 |
|
| 2007 |
Lou Y, Seipp RP, Cai B, Chen SS, Vitalis TZ, Choi KB, Jeffries AP, Gopaul RS, Li XL, Seliger B, Pearson TW, Jefferies WA. Tumour immunity and T cell memory are induced by low dose inoculation with a non-replicating adenovirus encoding TAP1. Vaccine. 25: 2331-9. PMID 17229499 DOI: 10.1016/J.Vaccine.2006.11.064 |
0.324 |
|
| 2006 |
Kotturi MF, Hunt SV, Jefferies WA. Roles of CRAC and Cav-like channels in T cells: more than one gatekeeper? Trends in Pharmacological Sciences. 27: 360-7. PMID 16766050 DOI: 10.1016/J.Tips.2006.05.007 |
0.701 |
|
| 2006 |
Dickstein DL, Biron KE, Ujiie M, Pfeifer CG, Jeffries AR, Jefferies WA. Abeta peptide immunization restores blood-brain barrier integrity in Alzheimer disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 426-33. PMID 16507760 DOI: 10.1096/Fj.05-3956Com |
0.657 |
|
| 2005 |
Vitalis TZ, Zhang QJ, Alimonti J, Chen SS, Basha G, Moise A, Tiong J, Tian MM, Choi KB, Waterfield D, Jeffries A, Jefferies WA. Using the TAP component of the antigen-processing machinery as a molecular adjuvant. Plos Pathogens. 1: e36. PMID 16389301 DOI: 10.1371/Journal.Ppat.0010036 |
0.752 |
|
| 2005 |
Kotturi MF, Jefferies WA. Molecular characterization of L-type calcium channel splice variants expressed in human T lymphocytes. Molecular Immunology. 42: 1461-74. PMID 15899519 DOI: 10.1016/J.Molimm.2005.01.014 |
0.696 |
|
| 2005 |
Lizée G, Basha G, Jefferies WA. Tails of wonder: endocytic-sorting motifs key for exogenous antigen presentation. Trends in Immunology. 26: 141-9. PMID 15745856 DOI: 10.1016/J.It.2005.01.005 |
0.611 |
|
| 2005 |
Creagh AL, Tiong JW, Tian MM, Haynes CA, Jefferies WA. Calorimetric studies of melanotransferrin (p97) and its interaction with iron. The Journal of Biological Chemistry. 280: 15735-41. PMID 15705575 DOI: 10.1074/Jbc.M414650200 |
0.755 |
|
| 2004 |
Leitch J, Fraser K, Lane C, Putzu K, Adema GJ, Zhang QJ, Jefferies WA, Bramson JL, Wan Y. CTL-dependent and -independent antitumor immunity is determined by the tumor not the vaccine. Journal of Immunology (Baltimore, Md. : 1950). 172: 5200-5. PMID 15100257 DOI: 10.4049/Jimmunol.172.9.5200 |
0.319 |
|
| 2004 |
Yang J, Tiong J, Kennard M, Jefferies WA. Deletion of the GPI pre-anchor sequence in human p97--a general approach for generating the soluble form of GPI-linked proteins. Protein Expression and Purification. 34: 28-48. PMID 14766298 DOI: 10.1016/J.Pep.2003.09.007 |
0.769 |
|
| 2004 |
Dickstein DL, Jeffries AR, Jefferies WA. P4-378 The effect of a-beta immunization on blood-brain barrier integrity in the TG2576 AD model mouse Neurobiology of Aging. 25: S582. DOI: 10.1016/S0197-4580(04)81936-5 |
0.65 |
|
| 2004 |
Pfeifer CG, Su G, McCalmon S, Jefferies WA. P2-126 Gene expression of brain endothelial cells in response to Alzheimer disease-associated stresses Neurobiology of Aging. 25: S260. DOI: 10.1016/S0197-4580(04)80873-X |
0.343 |
|
| 2003 |
Ujiie M, Dickstein DL, Carlow DA, Jefferies WA. Blood-brain barrier permeability precedes senile plaque formation in an Alzheimer disease model. Microcirculation (New York, N.Y. : 1994). 10: 463-70. PMID 14745459 DOI: 10.1038/Sj.Mn.7800212 |
0.646 |
|
| 2003 |
Moroo I, Ujiie M, Walker BL, Tiong JW, Vitalis TZ, Karkan D, Gabathuler R, Moise AR, Jefferies WA. Identification of a novel route of iron transcytosis across the mammalian blood-brain barrier. Microcirculation (New York, N.Y. : 1994). 10: 457-62. PMID 14745458 DOI: 10.1038/Sj.Mn.7800213 |
0.745 |
|
| 2003 |
Lizée G, Basha G, Tiong J, Julien JP, Tian M, Biron KE, Jefferies WA. Control of dendritic cell cross-presentation by the major histocompatibility complex class I cytoplasmic domain. Nature Immunology. 4: 1065-73. PMID 14566337 DOI: 10.1038/Ni989 |
0.765 |
|
| 2003 |
Kotturi MF, Carlow DA, Lee JC, Ziltener HJ, Jefferies WA. Identification and functional characterization of voltage-dependent calcium channels in T lymphocytes. The Journal of Biological Chemistry. 278: 46949-60. PMID 12954628 DOI: 10.1074/Jbc.M309268200 |
0.716 |
|
| 2002 |
Sala R, Jefferies WA, Walker B, Yang J, Tiong J, Law SK, Carlevaro MF, Di Marco E, Vacca A, Cancedda R, Cancedda FD, Ribatti D. The human melanoma associated protein melanotransferrin promotes endothelial cell migration and angiogenesis in vivo. European Journal of Cell Biology. 81: 599-607. PMID 12494997 DOI: 10.1078/0171-9335-00280 |
0.716 |
|
| 2002 |
Demeule M, Poirier J, Jodoin J, Bertrand Y, Desrosiers RR, Dagenais C, Nguyen T, Lanthier J, Gabathuler R, Kennard M, Jefferies WA, Karkan D, Tsai S, Fenart L, Cecchelli R, et al. High transcytosis of melanotransferrin (P97) across the blood-brain barrier. Journal of Neurochemistry. 83: 924-33. PMID 12421365 DOI: 10.1046/J.1471-4159.2002.01201.X |
0.365 |
|
| 2002 |
Ujiie M, Dickstein DL, Jefferies WA. p97 as a biomarker for Alzheimer disease. Frontiers in Bioscience : a Journal and Virtual Library. 7: e42-7. PMID 11815303 DOI: 10.2741/Ujiie |
0.664 |
|
| 2001 |
Jefferies WA, Dickstein DL, Ujiie M. Assessing p97 as an Alzheimer's disease serum biomarker. Journal of Alzheimer's Disease : Jad. 3: 339-344. PMID 12214055 DOI: 10.3233/Jad-2001-3309 |
0.663 |
|
| 2001 |
Feldman H, Gabathuler R, Kennard M, Nurminen J, Levy D, Foti S, Foti D, Beattie BL, Jefferies WA. Serum p97 levels as an aid to identifying Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 3: 507-516. PMID 12214037 DOI: 10.3233/Jad-2001-3510 |
0.309 |
|
| 2001 |
Walker BL, Tiong JW, Jefferies WA. Iron metabolism in mammalian cells. International Review of Cytology. 211: 241-78. PMID 11597005 DOI: 10.1016/S0074-7696(01)11020-X |
0.733 |
|
| 2000 |
Alimonti J, Zhang Q, Gabathuler R, Reid G, Chen SS, Jefferies WA. TAP expression provides a general method for improving the recognition of malignant cells in vivo. Nature Biotechnology. 18: 515-520. PMID 10802618 DOI: 10.1038/75373 |
0.335 |
|
| 2000 |
Zhang QJ, Chen SS, Saari CA, Massuci MG, Tufaro F, Jefferies WA. Evidence of selective processing of immunodominant epitopes in virally infected cells Journal of Immunology. 164: 4513-4521. PMID 10779752 DOI: 10.4049/Jimmunol.164.9.4513 |
0.329 |
|
| 1999 |
Yamada T, Tsujioka Y, Taguchi J, Takahashi M, Tsuboi Y, Moroo I, Yang J, Jefferies WA. Melanotransferrin is produced by senile plaque-associated reactive microglia in Alzheimer's disease. Brain Research. 845: 1-5. PMID 10529437 DOI: 10.1016/S0006-8993(99)01767-9 |
0.37 |
|
| 1999 |
Hegedus DD, Pfeifer TA, Theilmann DA, Kennard ML, Gabathuler R, Jefferies WA, Grigliatti TA. Differences in the expression and localization of human melanotransferrin in lepidopteran and dipteran insect cell lines. Protein Expression and Purification. 15: 296-307. PMID 10092489 DOI: 10.1006/Prep.1998.1021 |
0.346 |
|
| 1998 |
Gabathuler R, Alimonti J, Zhang Q, Kolaitis G, Reid G, Jefferies WA. Surrogate Antigen Processing Mediated by TAP-dependent Antigenic Peptide Secretion Journal of Cell Biology. 140: 17-27. PMID 9425150 DOI: 10.1083/Jcb.140.1.17 |
0.323 |
|
| 1996 |
Jefferies WA, Gabathuler R, Rothenberger S, Kennard ML. Pumping iron in the '90s. Trends in Cell Biology. 6: 223-228. PMID 15157460 DOI: 10.1016/0962-8924(96)10019-2 |
0.366 |
|
| 1996 |
Kennard ML, Feldman H, Yamada T, Jefferies WA. Serum levels of the iron binding protein p97 are elevated in Alzheimer's disease. Nature Medicine. 2: 1230-1235. PMID 8898750 DOI: 10.1038/Nm1196-1230 |
0.312 |
|
| 1996 |
Jefferies WA, Food MR, Gabathuler R, Rothenberger S, Yamada T, Yasuhara O, McGeer PL. Reactive microglia specifically associated with amyloid plaques in Alzheimer's disease brain tissue express melanotransferrin. Brain Research. 712: 122-6. PMID 8705294 DOI: 10.1016/0006-8993(95)01407-1 |
0.406 |
|
| 1996 |
Rothenberger S, Food MR, Gabathuler R, Kennard ML, Yamada T, Yasuhara O, McGeer PL, Jefferies WA. Coincident expression and distribution of melanotransferrin and transferrin receptor in human brain capillary endothelium. Brain Research. 712: 117-21. PMID 8705293 DOI: 10.1016/0006-8993(96)88505-2 |
0.401 |
|
| 1996 |
Brennan J, Mahon G, Mager DL, Jefferies WA, Takei F. Recognition of class I major histocompatibility complex molecules by Ly-49: specificities and domain interactions. The Journal of Experimental Medicine. 183: 1553-9. PMID 8666913 DOI: 10.1084/Jem.183.4.1553 |
0.303 |
|
| 1996 |
Feldman H, Kennard M, Yamada T, Adams S, Jefferies W. 680 Serum levels of the iron binding protein p97: A novel biological marker of Alzheimer's disease Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80682-8 |
0.339 |
|
| 1995 |
Kennard ML, Richardson DR, Gabathuler R, Ponka P, Jefferies WA. A novel iron uptake mechanism mediated by GPI-anchored human p97. The Embo Journal. 14: 4178-4186. DOI: 10.1002/J.1460-2075.1995.Tb00091.X |
0.372 |
|
| 1994 |
Gabathuler R, Reid G, Kolaitis G, Driscoll J, Jefferies WA. Comparison of cell lines deficient in antigen presentation reveals a functional role for TAP-1 alone in antigen processing. Journal of Experimental Medicine. 180: 1415-1425. PMID 7931074 DOI: 10.1084/Jem.180.4.1415 |
0.34 |
|
| 1992 |
Michaelis C, Banfield BW, Gruenheid S, Tsang Y, Lippe R, Jefferies WA, Wattenberg BW, Tufaro F. Toxin resistance and reduced secretion in a mouse L-cell mutant defective in herpes virus propagation Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 70: 1209-1217. PMID 1338412 DOI: 10.1139/O92-167 |
0.319 |
|
| 1991 |
Lippé R, Luke E, Kuah YT, Lomas C, Jefferies WA. Adenovirus infection inhibits the phosphorylation of major histocompatibility complex class I proteins. The Journal of Experimental Medicine. 174: 1159-66. PMID 1658186 DOI: 10.1084/Jem.174.5.1159 |
0.335 |
|
| 1990 |
Jefferies WA, Burgert HG. E3/19K from adenovirus 2 is an immunosubversive protein that binds to a structural motif regulating the intracellular transport of major histocompatibility complex class I proteins. Journal of Experimental Medicine. 172: 1653-1664. PMID 2147948 DOI: 10.1084/Jem.172.6.1653 |
0.341 |
|
| 1987 |
Paterson DJ, Jefferies WA, Green JR, Brandon MR, Corthesy P, Puklavec M, Williams AF. Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. Molecular Immunology. 24: 1281-90. PMID 2828930 DOI: 10.1016/0161-5890(87)90122-2 |
0.33 |
|
| 1985 |
Jefferies WA, Green JR, Williams AF. Authentic T helper CD4 (W3/25) antigen on rat peritoneal macrophages. The Journal of Experimental Medicine. 162: 117-27. PMID 3159821 DOI: 10.1084/Jem.162.1.117 |
0.3 |
|
| 1984 |
Jefferies WA, Brandon MR, Hunt SV, Williams AF, Gatter KC, Mason DY. Transferrin receptor on endothelium of brain capillaries Nature. 312: 162-163. PMID 6095085 DOI: 10.1038/312162A0 |
0.369 |
|
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