| Year |
Citation |
Score |
| 2020 |
Tapia R, Kralicek SE, Hecht GA. Enteropathogenic (EPEC) Recruitment of PAR Polarity Protein Atypical PKCζ to Pedestals and Cell-Cell Contacts Precedes Disruption of Tight Junctions in Intestinal Epithelial Cells. International Journal of Molecular Sciences. 21. PMID 31947656 DOI: 10.3390/Ijms21020527 |
0.465 |
|
| 2020 |
Kralicek SE, Carlino MJ, Hecht GA. Tu1452 ATYPICAL ENTEROPATHOGENIC E. COLI (EPEC) ISOLATES FROM DIARRHEAL SAMPLES WITH HIGH EPEC LOADS HAVE INCREASED AND PREFERENTIAL ADHESION TO COLONIC VERSUS SMALL INTESTINAL EPITHELIAL CELLS Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)33452-1 |
0.426 |
|
| 2020 |
Sitaraman L, Kralicek SE, Hecht GA. Su1200 CLINICAL CHARACTERISTICS AND PRESENTATION OF PATIENTS WITH ENTEROPATHOGENIC ESCHERICHIA COLI INFECTION: AN EMERGING ENTERIC PATHOGEN Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)32048-5 |
0.363 |
|
| 2019 |
Tapia R, Perez-Yepez EA, Carlino MJ, Karandikar UC, Kralicek SE, Estes MK, Hecht GA. Sperm Flagellar 1 Binds Actin in Intestinal Epithelial Cells and Contributes to Formation of Filopodia and Lamellipodia. Gastroenterology. PMID 31473225 DOI: 10.1053/J.Gastro.2019.08.031 |
0.422 |
|
| 2019 |
Carlino MJ, Kralicek SE, Hecht GA. Tu1593 – Virulence Phenotypes of Atypical Enteropathogenic Escherichia Coli Isolated from Patients with Diarrhea in Usa Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)39598-8 |
0.314 |
|
| 2019 |
Kralicek SE, Hecht GA, Pastrana RT. 693 – Atypical Pkcζ Activity and Recruitment to Pedestals Contributes to and Precedes Tight Junction Disruption Induced by Enteropathogenic Escherichia Coli (EPEC) Infection of Intestinal Epithelial Cells Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)37167-7 |
0.498 |
|
| 2019 |
Pastrana RT, Perez-Yepez EA, Carlino MJ, Kralicek SE, Hecht GA. 122 – Calponin-Homology and Microtubule-Associated Protein Interacts with Actin and Contributes to Cell Polarization and Migration of Intestinal Epithelial Cells Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)36856-8 |
0.421 |
|
| 2018 |
Kralicek SE, Nguyen M, Rhee KJ, Tapia R, Hecht G. EPEC NleH1 is significantly more effective in reversing colitis and reducing mortality than NleH2 via differential effects on host signaling pathways. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 29396422 DOI: 10.1038/S41374-017-0016-1 |
0.433 |
|
| 2018 |
Pastrana RT, Kralicek S, Hecht GA. 821 - Intestinal Epithelial Par Polarity Proteins are Mislocalized by Enteropathogenic E. Coli (EPEC) and in Inflamed Colonic Tissues from Patients with Crohn's Disease Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)30979-X |
0.408 |
|
| 2017 |
Tapia R, Kralicek SE, Hecht GA. Modulation of epithelial cell polarity by bacterial pathogens. Annals of the New York Academy of Sciences. PMID 28628193 DOI: 10.1111/Nyas.13388 |
0.431 |
|
| 2017 |
Tapia R, Kralicek SE, Hecht GA. EPEC effector EspF promotes Crumbs3 endocytosis and disrupts epithelial cell polarity. Cellular Microbiology. PMID 28618099 DOI: 10.1111/Cmi.12757 |
0.491 |
|
| 2017 |
Singhal M, Manzella C, Soni V, Alrefai WA, Saksena S, Hecht GA, Dudeja PK, Gill RK. Role of SHP2 Protein Tyrosine Phosphatase in SERT Inhibition by Enteropathogenic E. coli (EPEC). American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00011.2017. PMID 28209599 DOI: 10.1152/Ajpgi.00011.2017 |
0.437 |
|
| 2017 |
Kralicek S, Hecht GA. Enteropathogenic Escherichia Coli (EPEC) Effector NleH1 Suppresses Key Signaling Cascades to Attenuate Intestinal Inflammation in Mice Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)30973-3 |
0.369 |
|
| 2017 |
Kumar A, Bhat P, Chatterjee I, Anbazhagan AN, Saksena S, Alrefai WA, Hecht GA, Gill RK, Dudeja PK. Transcriptional Regulation of SLC26A3 by Enteropathogenic E.Coli Infection Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)30537-1 |
0.384 |
|
| 2016 |
Eppinga H, Fuhler GM, Peppelenbosch MP, Hecht GA. Gut Microbiota developments with emphasis on Inflammatory Bowel Disease: Report from the Gut Microbiota for Health World Summit 2016. Gastroenterology. PMID 27371370 DOI: 10.1053/J.Gastro.2016.06.024 |
0.307 |
|
| 2016 |
Kralicek S, Nguyen M, Hecht G. Tu1852 Enteropathogenic Escherichia coli (EPEC) Effector NleH1, but not NleH2, Suppresses Activation of MAP Kinase ERK1/2 In Vitro and In Vivo Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)33246-2 |
0.3 |
|
| 2016 |
Pastrana RT, Hecht G. Sa1416 EPEC Effector EspF Promotes Crumbs3 Endocytosis and Disrupts Epithelial Cell Polarity Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)31085-X |
0.371 |
|
| 2015 |
Gujral T, Kumar A, Priyamvada S, Saksena S, Gill RK, Hodges K, Alrefai WA, Hecht GA, Dudeja PK. Mechanisms of DRA recycling in Intestinal Epithelial Cells: Effect of Enteropathogenic E. coli. American Journal of Physiology. Cell Physiology. ajpcell.00107.2015. PMID 26447204 DOI: 10.1152/Ajpcell.00107.2015 |
0.443 |
|
| 2015 |
Nguyen M, Rizvi J, Hecht G. Expression of enteropathogenic Escherichia coli map is significantly different than that of other type III secreted effectors in vivo. Infection and Immunity. 83: 130-7. PMID 25312947 DOI: 10.1128/Iai.02467-14 |
0.368 |
|
| 2015 |
Pastrana RT, Hecht G. Mo1841 EPEC Affects the Crumbs Polarity Complex of Epithelial Cells Gastroenterology. 148. DOI: 10.1016/S0016-5085(15)32470-7 |
0.312 |
|
| 2014 |
Battle SE, Brady MJ, Vanaja SK, Leong JM, Hecht GA. Actin pedestal formation by enterohemorrhagic Escherichia coli enhances bacterial host cell attachment and concomitant type III translocation. Infection and Immunity. 82: 3713-22. PMID 24958711 DOI: 10.1128/Iai.01523-13 |
0.487 |
|
| 2014 |
Glotfelty LG, Zahs A, Hodges K, Shan K, Alto NM, Hecht GA. Enteropathogenic E. coli effectors EspG1/G2 disrupt microtubules, contribute to tight junction perturbation and inhibit restoration. Cellular Microbiology. 16: 1767-83. PMID 24948117 DOI: 10.1111/Cmi.12323 |
0.45 |
|
| 2014 |
Glotfelty LG, Zahs A, Iancu C, Shen L, Hecht GA. Microtubules are required for efficient epithelial tight junction homeostasis and restoration. American Journal of Physiology. Cell Physiology. 307: C245-54. PMID 24920678 DOI: 10.1152/Ajpcell.00336.2013 |
0.347 |
|
| 2014 |
Hodges K, Hecht GA. Mo1946 Interaction of EPEC EspF With 14-3-3 Drives the Redistribution of the Polarity Protein Par1b Leading to Disruption of Epithelial Tight Junctions Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)62536-1 |
0.356 |
|
| 2014 |
Gujral T, Kumar A, Priyamvada S, Gill RK, Alrefai WA, Hecht GA, Dudeja PK. Mo1757 Trafficking of SLC26A3 (DRA) in Intestinal Epithelial Cells: Effect of EPEC Infection Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)62374-X |
0.366 |
|
| 2014 |
Singhal M, Soni V, Kumar A, Alrefai WA, Saksena S, Hecht GA, Dudeja PK, Gill RK. Mo1750 Role of SHP2 Protein Tyrosine Phosphatase in SERT Inhibition by Enteropathogenic E. Coli Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)62367-2 |
0.411 |
|
| 2013 |
Hodges K, Hecht G. Bacterial infections of the small intestine. Current Opinion in Gastroenterology. 29: 159-63. PMID 23380575 DOI: 10.1097/Mog.0B013E32835B422C |
0.419 |
|
| 2013 |
Saulnier DM, Ringel Y, Heyman MB, Foster JA, Bercik P, Shulman RJ, Versalovic J, Verdu EF, Dinan TG, Hecht G, Guarner F. The intestinal microbiome, probiotics and prebiotics in neurogastroenterology. Gut Microbes. 4: 17-27. PMID 23202796 DOI: 10.4161/Gmic.22973 |
0.327 |
|
| 2013 |
Nguyen MT, Hecht GA. Tu2014 Expression of EPEC MAP Is Significantly Different Than That of Other Type 3 Secreted Effectors In Vivo Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63370-3 |
0.369 |
|
| 2013 |
Nguyen MT, Rhee K, Hecht GA. 892 EPEC NleH1 and NleH2 Protect Against Host Inflammation and Improve DSS-Induced Colitis and Survival in Mice Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)60567-3 |
0.302 |
|
| 2012 |
Glotfelty LG, Hecht GA. Enteropathogenic E. coli effectors EspG1/G2 disrupt tight junctions: new roles and mechanisms. Annals of the New York Academy of Sciences. 1258: 149-58. PMID 22731728 DOI: 10.1111/J.1749-6632.2012.06563.X |
0.51 |
|
| 2012 |
Annaba F, Sarwar Z, Gill RK, Ghosh A, Saksena S, Borthakur A, Hecht GA, Dudeja PK, Alrefai WA. Enteropathogenic Escherichia coli inhibits ileal sodium-dependent bile acid transporter ASBT American Journal of Physiology - Gastrointestinal and Liver Physiology. 302: G1216-G1222. PMID 22403793 DOI: 10.1152/Ajpgi.00017.2012 |
0.523 |
|
| 2012 |
Hodges K, Hecht G. Interspecies communication in the gut, from bacterial delivery to host-cell response. The Journal of Physiology. 590: 433-40. PMID 22106176 DOI: 10.1113/Jphysiol.2011.220822 |
0.468 |
|
| 2012 |
Guzman JE, Guzman YM, Royan SV, Rhee K, Jones R, Hecht GA. Mo1809 Enteropathogenic E. coli Non-Lee Encoded Effectors NleH1 and NleH2 Attenuate Activation of Mitogen-Activated Protein Kinases Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)62662-6 |
0.434 |
|
| 2012 |
Glotfelty L, Hecht GA. 213 The Effect of Enteropathogenic E. coli EspG1/2-mediated Microtubule Disruption on Intestinal Epithelial Tight Junction Regulation and Recovery Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)60202-9 |
0.465 |
|
| 2012 |
Battle S, Leong JM, Hecht GA. 87 EHEC Tir Effects Translocation of Type III Secretion System Effectors Partially Through Its Role in Intimate Adherence Gastroenterology. 142: S-21. DOI: 10.1016/S0016-5085(12)60082-1 |
0.327 |
|
| 2011 |
Rhee KJ, Cheng H, Harris A, Morin C, Kaper JB, Hecht G. Determination of spatial and temporal colonization of enteropathogenic E. coli and enterohemorrhagic E. coli in mice using bioluminescent in vivo imaging. Gut Microbes. 2: 34-41. PMID 21637016 DOI: 10.1016/S0016-5085(10)62688-1 |
0.411 |
|
| 2011 |
Hodges K, Koutsouris A, Hecht GA. EPEC ESPF Disrupts Tight Junction Barrier Function Through Direct Interaction With 14-3-3 Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)60036-X |
0.325 |
|
| 2010 |
Thanabalasuriar A, Koutsouris A, Hecht G, Gruenheid S. The bacterial virulence factor NleA's involvement in intestinal tight junction disruption during enteropathogenic E. coli infection is independent of its putative PDZ binding domain. Gut Microbes. 1: 114-118. PMID 21326920 DOI: 10.4161/Gmic.1.2.11685 |
0.438 |
|
| 2010 |
Royan SV, Jones RM, Koutsouris A, Roxas JL, Falzari K, Weflen AW, Kim A, Bellmeyer A, Turner JR, Neish AS, Rhee KJ, Viswanathan VK, Hecht GA. Enteropathogenic E. coli non-LEE encoded effectors NleH1 and NleH2 attenuate NF-κB activation. Molecular Microbiology. 78: 1232-45. PMID 21091507 DOI: 10.1111/J.1365-2958.2010.07400.X |
0.789 |
|
| 2010 |
Vingadassalom D, Campellone KG, Brady MJ, Skehan B, Battle SE, Robbins D, Kapoor A, Hecht G, Snapper SB, Leong JM. Enterohemorrhagic E. coli requires N-WASP for efficient type III translocation but not for EspFU-mediated actin pedestal formation. Plos Pathogens. 6: e1001056. PMID 20808845 DOI: 10.1371/Journal.Ppat.1001056 |
0.423 |
|
| 2010 |
Roxas JL, Koutsouris A, Bellmeyer A, Tesfay S, Royan S, Falzari K, Harris A, Cheng H, Rhee KJ, Hecht G. Enterohemorrhagic E. coli alters murine intestinal epithelial tight junction protein expression and barrier function in a Shiga toxin independent manner. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 1152-68. PMID 20479715 DOI: 10.1038/Labinvest.2010.91 |
0.414 |
|
| 2010 |
Weflen AW, Alto NM, Viswanathan VK, Hecht G. E. coli secreted protein F promotes EPEC invasion of intestinal epithelial cells via an SNX9-dependent mechanism. Cellular Microbiology. 12: 919-29. PMID 20088948 DOI: 10.1111/J.1462-5822.2010.01440.X |
0.814 |
|
| 2010 |
Thanabalasuriar A, Koutsouris A, Weflen A, Mimee M, Hecht G, Gruenheid S. The bacterial virulence factor NleA is required for the disruption of intestinal tight junctions by enteropathogenic Escherichia coli. Cellular Microbiology. 12: 31-41. PMID 19712078 DOI: 10.1111/J.1462-5822.2009.01376.X |
0.822 |
|
| 2010 |
Weflen AW, Alto NM, Hecht GA. 26 Enteropathogenic E. coli Secreted Protein F Interaction With Sorting Nexin 9 Induces Clathrin-Dependent Membrane Remodeling and Bacterial Invasion of Intestinal Epithelial Cells Independent of Dynamin Activity Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)60020-0 |
0.819 |
|
| 2009 |
Esmaili A, Nazir SF, Borthakur A, Yu D, Turner JR, Saksena S, Singla A, Hecht GA, Alrefai WA, Gill RK. Enteropathogenic Escherichia coli Infection Inhibits Intestinal Serotonin Transporter Function and Expression Gastroenterology. 137: 2074-2083. PMID 19747920 DOI: 10.1053/J.Gastro.2009.09.002 |
0.397 |
|
| 2009 |
Matkowskyj K, Royan SV, Blunier A, Hecht G, Rao M, Benya RV. Age-dependent differences in galanin-dependent colonic fluid secretion after infection with Salmonella typhimurium. Gut. 58: 1201-6. PMID 19671554 DOI: 10.1136/Gut.2008.163832 |
0.318 |
|
| 2009 |
Ashokkumar B, Kumar JS, Hecht GA, Said HM. Enteropathogenic Escherichia coli inhibits intestinal vitamin B1 (thiamin) uptake: studies with human-derived intestinal epithelial Caco-2 cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G825-33. PMID 19628653 DOI: 10.1152/Ajpgi.00250.2009 |
0.471 |
|
| 2009 |
Bellmeyer A, Cotton C, Kanteti R, Koutsouris A, Viswanathan VK, Hecht G. Enterohemorrhagic Escherichia coli suppresses inflammatory response to cytokines and its own toxin. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G576-81. PMID 19556613 DOI: 10.1152/Ajpgi.00050.2009 |
0.45 |
|
| 2009 |
Weflen AW, Alto NM, Hecht GA. Tight junctions and enteropathogenic E. coli. Annals of the New York Academy of Sciences. 1165: 169-74. PMID 19538303 DOI: 10.1111/J.1749-6632.2009.04060.X |
0.81 |
|
| 2009 |
Viswanathan VK, Hodges K, Hecht G. Enteric infection meets intestinal function: how bacterial pathogens cause diarrhoea. Nature Reviews. Microbiology. 7: 110-9. PMID 19116615 DOI: 10.1038/nrmicro2053 |
0.314 |
|
| 2009 |
Weflen AW, Hecht GA. 553 ESPF Promotes EPEC Invasion of Intestinal Epithelial Cells via An Snx9-Dependent, Dynamin-Independent Mechanism Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60388-7 |
0.789 |
|
| 2009 |
Royan SV, Jones R, Roxas JL, Koutsouris A, Bellmeyer A, Viswanathan V, Neish AS, Turner JR, Hecht GA. 118 Enteropathogenic E. coli Non-Lee Encoded Effectors NleH1 and NleH2 Inhibit NF-κB Activation Gastroenterology. 136: A-21. DOI: 10.1016/S0016-5085(09)60101-3 |
0.371 |
|
| 2008 |
Borthakur A, Gill RK, Tyagi S, Koutsouris A, Alrefai WA, Hecht GA, Ramaswamy K, Dudeja PK. The probiotic Lactobacillus acidophilus stimulates chloride/hydroxyl exchange activity in human intestinal epithelial cells Journal of Nutrition. 138: 1355-1359. PMID 18567760 DOI: 10.1093/Jn/138.7.1355 |
0.397 |
|
| 2008 |
Hodges K, Alto NM, Ramaswamy K, Dudeja PK, Hecht G. The enteropathogenic Escherichia coli effector protein EspF decreases sodium hydrogen exchanger 3 activity. Cellular Microbiology. 10: 1735-45. PMID 18433466 DOI: 10.1111/J.1462-5822.2008.01163.X |
0.484 |
|
| 2008 |
Viswanathan VK, Weflen A, Koutsouris A, Roxas JL, Hecht G. Enteropathogenic E. coli-induced barrier function alteration is not a consequence of host cell apoptosis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G1165-70. PMID 18356531 DOI: 10.1152/Ajpgi.00596.2007 |
0.813 |
|
| 2008 |
Weflen AW, Koutsouris A, Royan SV, Roxas JL, Viswanathan VK, Hecht G. M1174 Enteropathogenic E. coli-Induced Barrier Function Alteration Is Not a Consequence of Host Cell Death Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)61649-2 |
0.789 |
|
| 2008 |
Weflen AW, Alto NM, Viswanathan VK, Hecht G. 722 Differential Role of E. coli Secreted Protein F in the Engulfment of Enteropathogenic E. coli By Epithelial Cells and Macrophages Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)60484-9 |
0.791 |
|
| 2008 |
Esmaili A, Borthakur A, Nazir S, Yu D, Turner JR, Alrefai WA, Hecht G, Dudeja PK, Gill RK. 719 Mechanisms of Inhibition of Serotonin Transporter (SERT) in Response to Infection By Enteropathogenic E. coli (EPEC) Gastroenterology. 134: A-103. DOI: 10.1016/S0016-5085(08)60481-3 |
0.383 |
|
| 2008 |
Hodges K, Ramaswamy K, Dudeja PK, Hecht G. 718 Enhanced Cytoskeletal Association of Ezrin By ESPF Is Involved in EPEC-Mediated Suppression of NHE3 Activity Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)60480-1 |
0.438 |
|
| 2007 |
Alto NM, Weflen AW, Rardin MJ, Yarar D, Lazar CS, Tonikian R, Koller A, Taylor SS, Boone C, Sidhu SS, Schmid SL, Hecht GA, Dixon JE. The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways. The Journal of Cell Biology. 178: 1265-78. PMID 17893247 DOI: 10.1083/Jcb.200705021 |
0.79 |
|
| 2007 |
Gill RK, Borthakur A, Hodges K, Turner JR, Clayburgh DR, Saksena S, Zaheer A, Ramaswamy K, Hecht G, Dudeja PK. Mechanism underlying inhibition of intestinal apical Cl-/OH- exchange following infection with enteropathogenic E. coli Journal of Clinical Investigation. 117: 428-437. PMID 17256057 DOI: 10.1172/Jci29625 |
0.497 |
|
| 2006 |
McVay LD, Keilbaugh SA, Wong TM, Kierstein S, Shin ME, Lehrke M, Lefterova MI, Shifflett DE, Barnes SL, Cominelli F, Cohn SM, Hecht G, Lazar MA, Haczku A, Wu GD. Absence of bacterially induced RELMbeta reduces injury in the dextran sodium sulfate model of colitis. The Journal of Clinical Investigation. 116: 2914-23. PMID 17024245 DOI: 10.1172/Jci28121 |
0.467 |
|
| 2006 |
Hodges K, Gill R, Ramaswamy K, Dudeja PK, Hecht G. Rapid activation of Na+/H+ exchange by EPEC is PKC mediated. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G959-68. PMID 16782696 DOI: 10.1152/Ajpgi.00274.2005 |
0.422 |
|
| 2006 |
Sharma R, Tesfay S, Tomson FL, Kanteti RP, Viswanathan VK, Hecht G. Balance of bacterial pro- and anti-inflammatory mediators dictates net effect of enteropathogenic Escherichia coli on intestinal epithelial cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G685-94. PMID 16322091 DOI: 10.1152/Ajpgi.00404.2005 |
0.385 |
|
| 2006 |
Borthakur A, Gill RK, Hodges K, Ramaswamy K, Hecht G, Dudeja PK. Enteropathogenic Escherichia coli inhibits butyrate uptake in Caco-2 cells by altering the apical membrane MCT1 level American Journal of Physiology - Gastrointestinal and Liver Physiology. 290: G30-G35. PMID 16150873 DOI: 10.1152/Ajpgi.00302.2005 |
0.44 |
|
| 2005 |
Shifflett DE, Clayburgh DR, Koutsouris A, Turner JR, Hecht GA. Enteropathogenic E. coli disrupts tight junction barrier function and structure in vivo. Laboratory Investigation; a Journal of Technical Methods and Pathology. 85: 1308-24. PMID 16127426 DOI: 10.1038/Labinvest.3700330 |
0.427 |
|
| 2005 |
Tomson FL, Viswanathan VK, Kanack KJ, Kanteti RP, Straub KV, Menet M, Kaper JB, Hecht G. Enteropathogenic Escherichia coli EspG disrupts microtubules and in conjunction with Orf3 enhances perturbation of the tight junction barrier. Molecular Microbiology. 56: 447-64. PMID 15813736 DOI: 10.1111/J.1365-2958.2005.04571.X |
0.448 |
|
| 2005 |
Hecht GA. Early enterocyte responses to enteropathogenic E. coli. Journal of Pediatric Gastroenterology and Nutrition. 40: S32. PMID 15805842 DOI: 10.1097/00005176-200504001-00019 |
0.344 |
|
| 2004 |
Tomson FL, Koutsouris A, Viswanathan VK, Turner JR, Savkovic SD, Hecht G. Differing roles of protein kinase C-zeta in disruption of tight junction barrier by enteropathogenic and enterohemorrhagic Escherichia coli. Gastroenterology. 127: 859-69. PMID 15362041 DOI: 10.1053/J.Gastro.2004.06.014 |
0.336 |
|
| 2004 |
Viswanathan VK, Lukic S, Koutsouris A, Miao R, Muza MM, Hecht G. Cytokeratin 18 interacts with the enteropathogenic Escherichia coli secreted protein F (EspF) and is redistributed after infection. Cellular Microbiology. 6: 987-97. PMID 15339273 DOI: 10.1111/J.1462-5822.2004.00416.X |
0.476 |
|
| 2004 |
Muza-Moons MM, Schneeberger EE, Hecht GA. Enteropathogenic Escherichia coli infection leads to appearance of aberrant tight junctions strands in the lateral membrane of intestinal epithelial cells. Cellular Microbiology. 6: 783-93. PMID 15236645 DOI: 10.1111/J.1462-5822.2004.00404.X |
0.781 |
|
| 2004 |
Viswanathan VK, Koutsouris A, Lukic S, Pilkinton M, Simonovic I, Simonovic M, Hecht G. Comparative analysis of EspF from enteropathogenic and enterohemorrhagic Escherichia coli in alteration of epithelial barrier function. Infection and Immunity. 72: 3218-27. PMID 15155623 DOI: 10.1128/Iai.72.6.3218-3227.2004 |
0.447 |
|
| 2004 |
Hecht G, Hodges K, Gill RK, Kear F, Tyagi S, Malakooti J, Ramaswamy K, Dudeja PK. Differential regulation of Na+/H+ exchange isoform activities by enteropathogenic E. coli in human intestinal epithelial cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 287: G370-8. PMID 15075254 DOI: 10.1152/Ajpgi.00432.2003 |
0.436 |
|
| 2004 |
Viswanathan VK, Sharma R, Hecht G. Microbes and their products--physiological effects upon mammalian mucosa. Advanced Drug Delivery Reviews. 56: 727-62. PMID 15063587 DOI: 10.1016/J.Addr.2003.09.005 |
0.435 |
|
| 2003 |
Muza-Moons MM, Koutsouris A, Hecht G. Disruption of cell polarity by enteropathogenic Escherichia coli enables basolateral membrane proteins to migrate apically and to potentiate physiological consequences. Infection and Immunity. 71: 7069-78. PMID 14638797 DOI: 10.1128/IAI.71.12.7069-7078.2003 |
0.769 |
|
| 2003 |
Berkes J, Viswanathan VK, Savkovic SD, Hecht G. Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation. Gut. 52: 439-51. PMID 12584232 DOI: 10.1136/Gut.52.3.439 |
0.472 |
|
| 2003 |
Savkovic SD, Tomson FL, Muza M, Hecht G. Characterization of in vitro and in vivo murine models of human enteropathogenic E. coli (EPEC) infection Gastroenterology. 124: A558. DOI: 10.1016/S0016-5085(03)82826-3 |
0.38 |
|
| 2003 |
Hecht G, Gill R, Hodges K, Kear F, Saksena S, Alrefai WA, Ramaswamy K, Dudeja PK. EnteropathogenicE. coli (EPEC) infection inhibits apical Cl-/OH-exchange activity in Caco-2 cells Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)82440-X |
0.428 |
|
| 2003 |
Hecht G, Gill RK, Hodges K, Kear F, Tyagi S, Malakooti J, Ramaswamy K, Dudeja PK. Differential regulation of NHE2 and NHE3 (Na+/H+ exchanger isoforms) by enteropathogenic E. coli (EPEC) in caco-2 cells Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)81545-7 |
0.403 |
|
| 2003 |
Mittal N, Hecht G, Dirisina R, Bajalo N, Savkovic S, Barrett TA. T cell-induced clearance of enteropathogenic E. coli (EPEC) in murine intestine Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)80753-9 |
0.44 |
|
| 2003 |
Savkovic SD, Berkes JL, Enke R, Viswanathan VK, Hecht G. Type III secretion and EspF are involved in EPEC-induced epithelial inflammation Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)80554-1 |
0.349 |
|
| 2003 |
Viswanathan VK, Lukic S, Simonovic I, Koutsouris A, Miao R, Hecht G. Cytokeratin 18 interacts with enteropathogenic E. coli (EPEC) secreted protein F (EspF) and is redistributed following infection Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)80132-4 |
0.434 |
|
| 2002 |
Elliott SJ, O'Connell CB, Koutsouris A, Brinkley C, Donnenberg MS, Hecht G, Kaper JB. A gene from the locus of enterocyte effacement that is required for enteropathogenic Escherichia coli to increase tight-junction permeability encodes a chaperone for EspF. Infection and Immunity. 70: 2271-7. PMID 11953359 DOI: 10.1128/Iai.70.5.2271-2277.2002 |
0.338 |
|
| 2001 |
Simonovic I, Arpin M, Koutsouris A, Falk-Krzesinski HJ, Hecht G. Enteropathogenic Escherichia coli activates ezrin, which participates in disruption of tight junction barrier function. Infection and Immunity. 69: 5679-88. PMID 11500444 DOI: 10.1128/Iai.69.9.5679-5688.2001 |
0.553 |
|
| 2001 |
Hecht G. Microbes and microbial toxins: paradigms for microbial-mucosal interactions. VII. Enteropathogenic Escherichia coli: physiological alterations from an extracellular position. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G1-7. PMID 11408249 DOI: 10.1152/Ajpgi.2001.281.1.G1 |
0.514 |
|
| 2001 |
McNamara BP, Koutsouris A, O'Connell CB, Nougayréde JP, Donnenberg MS, Hecht G. Translocated EspF protein from enteropathogenic Escherichia coli disrupts host intestinal barrier function. The Journal of Clinical Investigation. 107: 621-9. PMID 11238563 DOI: 10.1172/Jci11138 |
0.514 |
|
| 2001 |
Hecht G, Koutsouris A, Muza MM. EPEC infection allows migration of β1 integrin to apical membrane which contributes to functional perturbations Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)81616-2 |
0.35 |
|
| 2001 |
Muza MM, Schneeberger E, Koutsouris A, Hecht G. EPEC intection of intestinal epithelial cells induces formation of aberrant tight junction strands in the lateral membrane Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80537-9 |
0.445 |
|
| 2000 |
Viswanathan VK, Hecht G. Innate immunity and the gut. Current Opinion in Gastroenterology. 16: 546-51. PMID 17031136 DOI: 10.1097/00001574-200011000-00015 |
0.391 |
|
| 2000 |
Matkowskyj KA, Danilkovich A, Marrero J, Savkovic SD, Hecht G, Benya RV. Galanin-1 receptor up-regulation mediates the excess colonic fluid production caused by infection with enteric pathogens. Nature Medicine. 6: 1048-51. PMID 10973327 DOI: 10.1038/79563 |
0.346 |
|
| 2000 |
Marrero JA, Matkowskyj KA, Yung K, Hecht G, Benya RV. Dextran sulfate sodium-induced murine colitis activates NF-kappaB and increases galanin-1 receptor expression. American Journal of Physiology. Gastrointestinal and Liver Physiology. 278: G797-804. PMID 10801272 DOI: 10.1152/Ajpgi.2000.278.5.G797 |
0.315 |
|
| 2000 |
Simonovic I, Konstantinou M, Brown N, Walden W, Hecht G. Infection of intestinal epithelial cells with enteropathogenic Escherichia coli activates iron regulatory processes Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)85327-5 |
0.415 |
|
| 2000 |
Simonovic I, Rosenberg J, Koutsouris A, Hecht G. Enteropathogenic E. coli dephosphorylates occludin disrupting its association with intestinal epithelial tight junctions Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)84868-4 |
0.451 |
|
| 2000 |
Hecht G, McNamara B, Koutsouris A, Donnenberg M. Enteropathogenic E. coli secreted protein F is required for alteration of host intestinal epithelial barrier function Gastroenterology. 118: A433. DOI: 10.1016/S0016-5085(00)83847-0 |
0.496 |
|
| 2000 |
Savkovic SD, Ramaswamy A, Koutsouris A, Hecht G. Enteropathogenic E. coli activates NF-kB, but does not increase paracellular permeability, by a calcium-independent/MAP kinase-dependent pathway Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)82488-9 |
0.326 |
|
| 1999 |
Hecht G, Marrero JA, Danilkovich A, Matkowskyj KA, Savkovic SD, Koutsouris A, Benya RV. Pathogenic Escherichia coli increase Cl- secretion from intestinal epithelia by upregulating galanin-1 receptor expression. The Journal of Clinical Investigation. 104: 253-62. PMID 10430606 DOI: 10.1172/Jci6373 |
0.465 |
|
| 1998 |
Benya RV, Matkowskyj KA, Danilkovich A, Hecht G. Galanin causes Cl- secretion in the human colon. Potential significance of inflammation-associated NF-kappa B activation on galanin-1 receptor expression and function. Annals of the New York Academy of Sciences. 863: 64-77. PMID 9928160 DOI: 10.1111/J.1749-6632.1998.Tb10684.X |
0.35 |
|
| 1997 |
Yuhan R, Koutsouris A, Savkovlc SD, Hecht G. Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeability Gastroenterology. 113: 1873-1882. PMID 9394726 DOI: 10.1016/S0016-5085(97)70006-4 |
0.394 |
|
| 1997 |
Savkovic SD, Koutsouris A, Hecht G. Activation of NF-κB in intestinal epithelial cells by enteropathogenic Escherichia coli American Journal of Physiology - Cell Physiology. 273: C1160-C1167. PMID 9357759 DOI: 10.1152/Ajpcell.1997.273.4.C1160 |
0.405 |
|
| 1997 |
Tripuraneni J, Koutsouris A, Pestic L, De Lanerolle P, Hecht G. The toxin of diarrheic shellfish poisoning, okadaic acid, increases intestinal epithelial paracellular permeability Gastroenterology. 112: 100-108. PMID 8978348 DOI: 10.1016/S0016-5085(97)70224-5 |
0.4 |
|
| 1994 |
Spitz J, Hecht G, Taveras M, Aoys E, Alverdy J. The effect of dexamethasone administration on rat intestinal permeability: The role of bacterial adherence Gastroenterology. 106: 35-41. PMID 8276206 DOI: 10.1016/S0016-5085(94)94155-6 |
0.38 |
|
| 1994 |
Hecht G, Robinson B, Koutsouris A. Reversible disassembly of an intestinal epithelial monolayer by prolonged exposure to phorbol ester American Journal of Physiology - Gastrointestinal and Liver Physiology. 266: G214-G221. PMID 8141294 DOI: 10.1152/Ajpgi.1994.266.2.G214 |
0.386 |
|
| 1992 |
Hecht G, Koutsouris A, Pothoulakis C, LaMont JT, Madara JL. Clostridium difficile toxin B disrupts the barrier function of T84 monolayers. Gastroenterology. 102: 416-23. PMID 1732112 DOI: 10.1016/0016-5085(92)90085-D |
0.42 |
|
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