Joseph R. Cohen, Ph.D. - Related publications

Affiliations: 
Laboratory of Tumor Immunology and Biology National Cancer Institute, Rockville, MD, United States 
Area:
Cancer
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Wang D, Hu A, Peng H, Li D, Zhang L. Tumor-promoting function of PIMREG in glioma by activating the β-catenin pathway. 3 Biotech. 11: 380. PMID 34458056 DOI: 10.1007/s13205-021-02922-5   
2021 Hou B, Li W, Xia P, Zhao F, Liu Z, Zeng Q, Wang S, Chang D. LHPP suppresses colorectal cancer cell migration and invasion in vitro and in vivo by inhibiting Smad3 phosphorylation in the TGF-β pathway. Cell Death Discovery. 7: 273. PMID 34608127 DOI: 10.1038/s41420-021-00657-z   
2021 Wang C, Tu H, Yang L, Ma C, Hu J, Luo J, Wang H. FOXN3 inhibits cell proliferation and invasion via modulating the AKT/MDM2/p53 axis in human glioma. Aging. 13. PMID 34511432 DOI: 10.18632/aging.203499   
2021 Chen J, Mai H, Chen H, Zhou B, Hou J, Jiang DK. Pan-Cancer Analysis Identified as a Potential Biomarker for Multiple Tumor Types. Frontiers in Molecular Biosciences. 8: 693651. PMID 34490347 DOI: 10.3389/fmolb.2021.693651   
2021 Sato A, Rahman NIA, Shimizu A, Ogita H. Cell-to-cell contact-mediated regulation of tumor behavior in the tumor microenvironment. Cancer Science. PMID 34420253 DOI: 10.1111/cas.15114   
2021 Li W, Song P, Zhao M, Gao L, Xie J, You C. BOP1 Used as a Novel Prognostic Marker and Correlated with Tumor Microenvironment in Pan-Cancer. Journal of Oncology. 2021: 3603030. PMID 34603446 DOI: 10.1155/2021/3603030   
2021 Su X, Xu Y, Fox GC, Xiang J, Kwakwa KA, Davis JL, Belle JI, Lee WC, Wong WH, Fontana F, Hernandez-Aya L, Kobayashi T, Tomasson HM, Su J, Bakewell SJ, et al. Breast cancer derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment. The Journal of Clinical Investigation. PMID 34520398 DOI: 10.1172/JCI145296   
2021 Bondoc A, Glaser K, Jin K, Lake C, Cairo S, Geller J, Tiao G, Aronow B. Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma. Communications Biology. 4: 1049. PMID 34497364 DOI: 10.1038/s42003-021-02562-8   
2021 Zhang N, Shao F, Jia W. Upregulation of microfibrillar-associated protein 2 is closely associated with tumor angiogenesis and poor prognosis in hepatocellular carcinoma. Oncology Letters. 22: 739. PMID 34466151 DOI: 10.3892/ol.2021.13000   
2021 Yan Y, Zhang Y, Li M, Zhang Y, Zhang X, Zhang X, Xu Y, Wei W, Wang J, Xu X, Song Q, Zhao C. C644-0303, A Small Molecule Inhibitor of Wnt/β-catenin Pathway, Suppresses Colorectal Cancer Growth. Cancer Science. PMID 34431598 DOI: 10.1111/cas.15118   
2021 Liu A, Zhou K, Martínez MA, Lopez-Torres B, Martínez M, Martínez-Larrañaga MR, Wang X, Anadón A, Ares I. A "Janus" face of the RASSF4 signal in cell fate. Journal of Cellular Physiology. PMID 34553373 DOI: 10.1002/jcp.30592   
2021 Huang TH, Mokgautsi N, Huang YJ, Wu ATH, Huang HS. Comprehensive Omics Analysis of a Novel Small-Molecule Inhibitor of Chemoresistant Oncogenic Signatures in Colorectal Cancer Cell with Antitumor Effects. Cells. 10. PMID 34440739 DOI: 10.3390/cells10081970   
2021 Yao J, Yang J, Yang Z, Wang XP, Yang T, Ji B, Zhang ZY. FBXW11 contributes to stem-cell-like features and liver metastasis through regulating HIC1-mediated SIRT1 transcription in colorectal cancer. Cell Death & Disease. 12: 930. PMID 34642302 DOI: 10.1038/s41419-021-04185-7   
2021 Ding X, Chen T, Shi Q, Nan P, Wang X, Xie D, Li J. INTS6 promotes colorectal cancer progression by activating of AKT and ERK signaling. Experimental Cell Research. 112826. PMID 34508742 DOI: 10.1016/j.yexcr.2021.112826   
2021 Zhou N, Li S, Wu D, Zhang F, Tang F, Li Y. The lncRNA Promotes Hepatocellular Carcinoma Cell Cycle Progression by Regulating the HuR/CDK4 Axis. Dna and Cell Biology. PMID 34558987 DOI: 10.1089/dna.2021.0235   
2021 Wang Z, Zhao T, Zhang S, Wang J, Chen Y, Zhao H, Yang Y, Shi S, Chen Q, Liu K. The Wnt signaling pathway in tumorigenesis, pharmacological targets, and drug development for cancer therapy. Biomarker Research. 9: 68. PMID 34488905 DOI: 10.1186/s40364-021-00323-7   
2021 Wang K, Qiu X, Zhao Y, Wang H, Chen L. The Wnt/β-catenin signaling pathway in the tumor microenvironment of hepatocellular carcinoma. Cancer Biology & Medicine. PMID 34591416 DOI: 10.20892/j.issn.2095-3941.2021.0306   
2021 Chen Y, Zhang Z, Henson ES, Cuddihy A, Haigh K, Wang R, Haigh JJ, Gibson SB. Autophagy inhibition by TSSC4 (tumor suppressing subtransferable candidate 4) contributes to sustainable cancer cell growth. Autophagy. 1-23. PMID 34530675 DOI: 10.1080/15548627.2021.1973338   
2021 Li W, Hu S, Tian C, Wan X, Yu W, Guo P, Zhao F, Hua C, Lu X, Xue G, Han S, Guo W, Wang D, Deng W. TRIP4 transcriptionally activates DDIT4 and subsequent mTOR signaling to promote glioma progression. Free Radical Biology & Medicine. PMID 34648907 DOI: 10.1016/j.freeradbiomed.2021.10.009   
2021 Zhang J, Zhai J, Wong CC, Chen H, Wang X, Ji J, Yu J. A novel amplification gene PCI domain containing 2 (PCID2) promotes colorectal cancer through directly degrading a tumor suppressor promyelocytic leukemia (PML). Oncogene. PMID 34625711 DOI: 10.1038/s41388-021-01941-z   
2021 Zakir U, Siddiqui NN, Naqvi FU, Khan R. Aberrant STAT1 methylation as a non-invasive biomarker in blood of HCV induced hepatocellular carcinoma. Cancer Biomarkers : Section a of Disease Markers. PMID 34657877 DOI: 10.3233/CBM-210216   
2021 Sun Y, Manceau A, Frydman L, Cappuccio L, Neves D, Basso V, Wang H, Fombonne J, Maisse C, Mehlen P, Paradisi A. Δ40p53 isoform up-regulates netrin-1/UNC5B expression and potentiates netrin-1 pro-oncogenic activity. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34470826 DOI: 10.1073/pnas.2103319118   
2021 Biyik-Sit R, Kruer T, Dougherty S, Bradley JA, Wilkey DW, Merchant ML, Trent JO, Clem BF. Nuclear Pyruvate Kinase M2 (PKM2) Contributes to Phosphoserine Aminotransferase 1 (PSAT1)-Mediated Cell Migration in EGFR-Activated Lung Cancer Cells. Cancers. 13. PMID 34439090 DOI: 10.3390/cancers13163938   
2021 Trivedi P, Patel SK, Bellavia D, Messina E, Palermo R, Ceccarelli S, Marchese C, Anastasiadou E, Minter LM, Felli MP. When Viruses Cross Developmental Pathways. Frontiers in Cell and Developmental Biology. 9: 691644. PMID 34422814 DOI: 10.3389/fcell.2021.691644   
2021 Nowicki A, Kulus M, Wieczorkiewicz M, Pieńkowski W, Stefańska K, Skupin-Mrugalska P, Bryl R, Mozdziak P, Kempisty B, Piotrowska-Kempisty H. Ovarian Cancer and Cancer Stem Cells-Cellular and Molecular Characteristics, Signaling Pathways, and Usefulness as a Diagnostic Tool in Medicine and Oncology. Cancers. 13. PMID 34439332 DOI: 10.3390/cancers13164178   
2021 Wu SY, Lin KC, Lawal B, Wu ATH, Wu CZ. MXD3 as an onco-immunological biomarker encompassing the tumor microenvironment, disease staging, prognoses, and therapeutic responses in multiple cancer types. Computational and Structural Biotechnology Journal. 19: 4970-4983. PMID 34584637 DOI: 10.1016/j.csbj.2021.08.047   
2021 Tan T, Li J, Luo R, Wang R, Yin L, Liu M, Zeng Y, Zeng Z, Xie T. Recent Advances in Understanding the Mechanisms of Elemene in Reversing Drug Resistance in Tumor Cells: A Review. Molecules (Basel, Switzerland). 26. PMID 34641334 DOI: 10.3390/molecules26195792   
2021 Wang Y, Li X, Peng S, Hu H, Wang Y, Shao M, Feng G, Liu Y, Bai Y. Single-Cell Analysis Reveals Spatial Heterogeneity of Immune Cells in Lung Adenocarcinoma. Frontiers in Cell and Developmental Biology. 9: 638374. PMID 34513820 DOI: 10.3389/fcell.2021.638374   
2021 Dong C, Li X, Yang J, Yuan D, Zhou Y, Zhang Y, Shi G, Zhang R, Liu J, Fu P, Sun M. PPFIBP1 induces glioma cell migration and invasion through FAK/Src/JNK signaling pathway. Cell Death & Disease. 12: 827. PMID 34480020 DOI: 10.1038/s41419-021-04107-7   
2021 Chen R, Sheng C, Ma R, Zhang L, Yang L, Chen Y. PLAC1 is an independent predictor of poor survival, and promotes cell proliferation and invasion in cervical cancer. Molecular Medicine Reports. 24. PMID 34523695 DOI: 10.3892/mmr.2021.12440   
2021 Gui S, Chen P, Liu Y, Chen Q, Cheng T, Lv S, Zhou T, Song Z, Xiao J, He W, Yuan S, Cheng Z. TUBA1C expression promotes proliferation by regulating the cell cycle and indicates poor prognosis in glioma. Biochemical and Biophysical Research Communications. 577: 130-138. PMID 34517210 DOI: 10.1016/j.bbrc.2021.08.079   
2021 Pan K, Fu J, Xu W. Role of Ubiquitin-Specific Peptidase 47 in Cancers and Other Diseases. Frontiers in Cell and Developmental Biology. 9: 726632. PMID 34604226 DOI: 10.3389/fcell.2021.726632   
2021 Zhou S, Cisse B. Regulation of Microglia for the Treatment of Glioma. World Neurosurgery. 154: 222-227. PMID 34583499 DOI: 10.1016/j.wneu.2021.06.107   
2021 Buechel D, Sugiyama N, Rubinstein N, Saxena M, Kalathur RKR, Lüönd F, Vafaizadeh V, Valenta T, Hausmann G, Cantù C, Basler K, Christofori G. Parsing β-catenin's cell adhesion and Wnt signaling functions in malignant mammary tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34408016 DOI: 10.1073/pnas.2020227118   
2021 Li G, Guo J, Zheng Y, Ding W, Han Z, Qin L, Mo W, Luo M. CXCR5 guides migration and tumor eradication of anti-EGFR chimeric antigen receptor T cells. Molecular Therapy Oncolytics. 22: 507-517. PMID 34553036 DOI: 10.1016/j.omto.2021.07.003   
2021 Supsavhad W, Hassan BB, Simmons JK, Dirksen WP, Elshafae SM, Kohart NA, Demirer AA, Rosol TJ. Effect of Dickkopf-1 (Dkk-1) and SP600125, a JNK Inhibitor, on Wnt Signaling in Canine Prostate Cancer Growth and Bone Metastases. Veterinary Sciences. 8. PMID 34437475 DOI: 10.3390/vetsci8080153   
2021 Li L, Wei H, Zhang YW, Zhao S, Che G, Wang Y, Chen L. Differential expression of long non-coding RNAs as diagnostic markers for lung cancer and other malignant tumors. Aging. 13. PMID 34670194 DOI: 10.18632/aging.203523   
2021 Andrijes R, Hejmadi RK, Pugh M, Rajesh S, Novitskaya V, Ibrahim M, Overduin M, Tselepis C, Middleton GW, Győrffy B, Beggs AD, Berditchevski F. Tetraspanin 6 is a regulator of carcinogenesis in colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34521767 DOI: 10.1073/pnas.2011411118   
2021 Kadry YA, Lee JY, Witze ES. Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis. Open Biology. 11: 210033. PMID 34610265 DOI: 10.1098/rsob.210033   
2021 Caforio M, de Billy E, De Angelis B, Iacovelli S, Quintarelli C, Paganelli V, Folgiero V. PI3K/Akt Pathway: The Indestructible Role of a Vintage Target as a Support to the Most Recent Immunotherapeutic Approaches. Cancers. 13. PMID 34439194 DOI: 10.3390/cancers13164040   
2021 Li M, Cai L, Wang X, Yu Y, Jian W, Bao G, Gao Z, Guo J, Zhang J, Li C, Zhang C. RHBDD1 promotes proliferation, migration, invasion and EMT in renal cell carcinoma via the EGFR/AKT signaling pathway. Molecular Medicine Reports. 24. PMID 34581421 DOI: 10.3892/mmr.2021.12466   
2021 Leystra AA, Harvey KN, Kaunga E, Hensley H, Vanderveer LA, Devarajan K, Clapper ML. High Variability in Cellular Proliferation, Gene Expression, and Cytokine Production in the Nonneoplastic Colonic Epithelium of Young Mice. Frontiers in Oncology. 11: 705562. PMID 34513688 DOI: 10.3389/fonc.2021.705562   
2021 Xu H, Wong CC, Li W, Zhou Y, Li Y, Wang L, Liu L, Yu J. RING-finger protein 6 promotes colorectal tumorigenesis by transcriptionally activating SF3B2. Oncogene. PMID 34611311 DOI: 10.1038/s41388-021-01872-9   
2021 Cheng L, Creasy T, Pilataxi F, Greenlees L, Vence L, Sridhar S, Streicher K. Effects of combination treatment with durvalumab plus tremelimumab on the tumor microenvironment in non-small-cell lung carcinoma. Cancer Immunology, Immunotherapy : Cii. PMID 34623465 DOI: 10.1007/s00262-021-03065-5   
2021 Araújo TG, Mota STS, Ferreira HSV, Ribeiro MA, Goulart LR, Vecchi L. Annexin A1 as a Regulator of Immune Response in Cancer. Cells. 10. PMID 34571894 DOI: 10.3390/cells10092245   
2021 Taguchi J, Shibata H, Kabata M, Kato M, Fukuda K, Tanaka A, Ohta S, Ukai T, Mitsunaga K, Yamada Y, Nagaoka SI, Yamazawa S, Ohnishi K, Woltjen K, Ushiku T, et al. DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency. Nature Communications. 12: 5041. PMID 34413299 DOI: 10.1038/s41467-021-25249-4   
2021 Stasevich EM, Murashko MM, Zinevich LS, Demin DE, Schwartz AM. The Role of Non-Coding RNAs in the Regulation of the Proto-Oncogene MYC in Different Types of Cancer. Biomedicines. 9. PMID 34440124 DOI: 10.3390/biomedicines9080921   
2021 Zhang Z, Li X, Yan X, Qiu H, Li G, Guo X, Lu Y, Yang J, Jiao M, Chen X, Zhu S, Dang C, Wang W, Chu D. Delta-like ligand 4 level in colorectal cancer is associated with tumor aggressiveness, body mass index and clinical outcome. Cancer Biomarkers : Section a of Disease Markers. PMID 34487019 DOI: 10.3233/CBM-200986   
2021 Manrique-Rincón AJ, Ruas LP, Fogagnolo CT, Brenneman RJ, Berezhnoy A, Castelucci B, Consonni SR, Gilboa E, Bajgelman MC. Aptamer-mediated transcriptional gene silencing of inhibits regulatory T cells and potentiates antitumor response. Molecular Therapy. Nucleic Acids. 25: 143-151. PMID 34457999 DOI: 10.1016/j.omtn.2021.05.005   
2021 Zhang M, Wang D, Su L, Ma J, Wang S, Cui M, Hong S, Guan B, Ma X. Activity of Wnt/PCP Regulation Pathway Classifies Patients of Low-Grade Glioma Into Molecularly Distinct Subgroups With Prognostic Difference. Frontiers in Oncology. 11: 726034. PMID 34540693 DOI: 10.3389/fonc.2021.726034