Tarek Z. Deeb, Ph.D. - Publications

Affiliations: 
2007 The George Washington University, Washington, DC, United States 
Area:
Neuroscience Biology, Physiology Biology

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Kelley MR, Deeb TZ, Brandon NJ, Dunlop J, Davies PA, Moss SJ. Compromising KCC2 transporter activity enhances the development of continuous seizure activity. Neuropharmacology. PMID 27108931 DOI: 10.1016/j.neuropharm.2016.04.029  0.52
2016 Nakamura Y, Morrow DH, Modgil A, Huyghe D, Deeb TZ, Lumb MJ, Davies PA, Moss SJ. Proteomic characterization of inhibitory synapses using a novel pHluorin-tagged GABAAR α2 subunit knock-in mouse. The Journal of Biological Chemistry. PMID 27044742 DOI: 10.1074/jbc.M116.724443  0.52
2016 Trattnig SM, Gasiorek A, Deeb TZ, Ortiz EJ, Moss SJ, Jensen AA, Davies PA. Copper and protons directly activate the zinc-activated channel. Biochemical Pharmacology. PMID 26872532 DOI: 10.1016/j.bcp.2016.02.004  0.52
2015 Sivakumaran S, Cardarelli RA, Maguire J, Kelley MR, Silayeva L, Morrow DH, Mukherjee J, Moore YE, Mather RJ, Duggan ME, Brandon NJ, Dunlop J, Zicha S, Moss SJ, Deeb TZ. Selective Inhibition of KCC2 Leads to Hyperexcitability and Epileptiform Discharges in Hippocampal Slices and In Vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8291-6. PMID 26019342 DOI: 10.1523/JNEUROSCI.5205-14.2015  0.52
2015 Silayeva L, Deeb TZ, Hines RM, Kelley MR, Munoz MB, Lee HH, Brandon NJ, Dunlop J, Maguire J, Davies PA, Moss SJ. KCC2 activity is critical in limiting the onset and severity of status epilepticus. Proceedings of the National Academy of Sciences of the United States of America. 112: 3523-8. PMID 25733865 DOI: 10.1073/pnas.1415126112  0.52
2015 Nakamura Y, Darnieder LM, Deeb TZ, Moss SJ. Regulation of GABAARs by phosphorylation. Advances in Pharmacology (San Diego, Calif.). 72: 97-146. PMID 25600368 DOI: 10.1016/bs.apha.2014.11.008  0.52
2014 Kahle KT, Merner ND, Friedel P, Silayeva L, Liang B, Khanna A, Shang Y, Lachance-Touchette P, Bourassa C, Levert A, Dion PA, Walcott B, Spiegelman D, Dionne-Laporte A, Hodgkinson A, ... ... Deeb TZ, et al. Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy. Embo Reports. 15: 766-74. PMID 24928908 DOI: 10.15252/embr.201438840  0.52
2014 Terunuma M, Revilla-Sanchez R, Quadros IM, Deng Q, Deeb TZ, Lumb M, Sicinski P, Haydon PG, Pangalos MN, Moss SJ. Postsynaptic GABAB receptor activity regulates excitatory neuronal architecture and spatial memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 804-16. PMID 24431439 DOI: 10.1523/JNEUROSCI.3320-13.2013  0.52
2013 Kahle KT, Deeb TZ, Puskarjov M, Silayeva L, Liang B, Kaila K, Moss SJ. Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2. Trends in Neurosciences. 36: 726-37. PMID 24139641 DOI: 10.1016/j.tins.2013.08.006  0.52
2013 Baptista-Hon DT, Deeb TZ, Lambert JJ, Peters JA, Hales TG. The minimum M3-M4 loop length of neurotransmitter-activated pentameric receptors is critical for the structural integrity of cytoplasmic portals. The Journal of Biological Chemistry. 288: 21558-68. PMID 23740249 DOI: 10.1074/jbc.M113.481689  0.52
2013 Deeb TZ, Nakamura Y, Frost GD, Davies PA, Moss SJ. Disrupted Cl(-) homeostasis contributes to reductions in the inhibitory efficacy of diazepam during hyperexcited states. The European Journal of Neuroscience. 38: 2453-67. PMID 23627375 DOI: 10.1111/ejn.12241  0.52
2012 Deeb TZ, Maguire J, Moss SJ. Possible alterations in GABAA receptor signaling that underlie benzodiazepine-resistant seizures. Epilepsia. 53: 79-88. PMID 23216581 DOI: 10.1111/epi.12037  0.52
2012 Othman NA, Gallacher M, Deeb TZ, Baptista-Hon DT, Perry DC, Hales TG. Influences on blockade by t-butylbicyclo-phosphoro-thionate of GABA(A) receptor spontaneous gating, agonist activation and desensitization. The Journal of Physiology. 590: 163-78. PMID 22083597 DOI: 10.1113/jphysiol.2011.213249  0.8
2012 Baptista-Hon DT, Deeb TZ, Othman NA, Sharp D, Hales TG. The 5-HT3B subunit affects high-potency inhibition of 5-HT3 receptors by morphine. British Journal of Pharmacology. 165: 693-704. PMID 21740409 DOI: 10.1111/j.1476-5381.2011.01582.x  0.8
2011 Deeb TZ, Lee HH, Walker JA, Davies PA, Moss SJ. Hyperpolarizing GABAergic transmission depends on KCC2 function and membrane potential. Channels (Austin, Tex.). 5: 475-81. PMID 22082832 DOI: 10.4161/chan.5.6.17952  0.52
2011 Odajima J, Wills ZP, Ndassa YM, Terunuma M, Kretschmannova K, Deeb TZ, Geng Y, Gawrzak S, Quadros IM, Newman J, Das M, Jecrois ME, Yu Q, Li N, Bienvenu F, et al. Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. Developmental Cell. 21: 655-68. PMID 21944720 DOI: 10.1016/j.devcel.2011.08.009  0.52
2011 Lee HH, Deeb TZ, Walker JA, Davies PA, Moss SJ. NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents. Nature Neuroscience. 14: 736-43. PMID 21532577 DOI: 10.1038/nn.2806  0.52
2010 Wu DF, Othman NA, Sharp D, Mahendra A, Deeb TZ, Hales TG. A conserved cysteine residue in the third transmembrane domain is essential for homomeric 5-HT3 receptor function. The Journal of Physiology. 588: 603-16. PMID 19933756 DOI: 10.1113/jphysiol.2009.181719  0.8
2009 Deeb TZ, Sharp D, Hales TG. Direct subunit-dependent multimodal 5-hydroxytryptamine3 receptor antagonism by methadone. Molecular Pharmacology. 75: 908-17. PMID 19131665 DOI: 10.1124/mol.108.053322  0.8
2008 Livesey MR, Cooper MA, Deeb TZ, Carland JE, Kozuska J, Hales TG, Lambert JJ, Peters JA. Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor. The Journal of Biological Chemistry. 283: 19301-13. PMID 18474595 DOI: 10.1074/jbc.M802406200  0.52
2007 Deeb TZ, Carland JE, Cooper MA, Livesey MR, Lambert JJ, Peters JA, Hales TG. Dynamic modification of a mutant cytoplasmic cysteine residue modulates the conductance of the human 5-HT3A receptor. The Journal of Biological Chemistry. 282: 6172-82. PMID 17200121 DOI: 10.1074/jbc.M607698200  0.52
2007 McCartney MR, Deeb TZ, Henderson TN, Hales TG. Tonically active GABAA receptors in hippocampal pyramidal neurons exhibit constitutive GABA-independent gating. Molecular Pharmacology. 71: 539-48. PMID 17090706 DOI: 10.1124/mol.106.028597  0.8
2006 Peters JA, Carland JE, Cooper MA, Livesey MR, Deeb TZ, Hales TG, Lambert JJ. Novel structural determinants of single-channel conductance in nicotinic acetylcholine and 5-hydroxytryptamine type-3 receptors. Biochemical Society Transactions. 34: 882-6. PMID 17052220 DOI: 10.1042/BST0340882  0.52
2006 Hales TG, Deeb TZ, Tang H, Bollan KA, King DP, Johnson SJ, Connolly CN. An asymmetric contribution to gamma-aminobutyric type A receptor function of a conserved lysine within TM2-3 of alpha1, beta2, and gamma2 subunits. The Journal of Biological Chemistry. 281: 17034-43. PMID 16627470 DOI: 10.1074/jbc.M603599200  0.52
2006 Hales TG, Dunlop JI, Deeb TZ, Carland JE, Kelley SP, Lambert JJ, Peters JA. Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and alpha4beta2 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 281: 8062-71. PMID 16407231 DOI: 10.1074/jbc.M513222200  0.52
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