Dara L. Dickstein, Ph.D. - Publications

Affiliations: 
2005 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Neuroscience Biology, Pathology

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Sharma R, Cramer NP, Perry B, Adahman Z, Murphy EK, Xu X, Dardzinski BJ, Galdzicki Z, Perl DP, Dickstein DL, Iacono D. Chronic Exposure to High Altitude: Synaptic, Astroglial and Memory Changes. Scientific Reports. 9: 16406. PMID 31712561 DOI: 10.1038/s41598-019-52563-1  0.36
2019 Miller ML, Chadwick B, Dickstein DL, Purushothaman I, Egervari G, Rahman T, Tessereau C, Hof PR, Roussos P, Shen L, Baxter MG, Hurd YL. Cell- and layer-specific transcriptomic strategy for characterizing the molecular phenotype of rat cortical neurons using laser capture microdissection and massively parallel RNA sequencing. Molecular Psychiatry. 24: 473. PMID 30899095 DOI: 10.1038/s41380-019-0390-8  0.56
2018 Raghanti MA, Wicinski B, Meierovich R, Warda T, Dickstein DL, Reidenberg JS, Tang CY, George JC, Hans Thewissen JGM, Butti C, Hof PR. A comparison of the cortical structure of the bowhead whale (Balaena mysticetus), a basal mysticete, with other cetaceans. Anatomical Record (Hoboken, N.J. : 2007). PMID 30332717 DOI: 10.1002/ar.23991  0.56
2018 Miller ML, Chadwick B, Dickstein DL, Purushothaman I, Egervari G, Rahman T, Tessereau C, Hof PR, Roussos P, Shen L, Baxter MG, Hurd YL. Adolescent exposure to Δ-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons. Molecular Psychiatry. PMID 30283037 DOI: 10.1038/s41380-018-0243-x  0.56
2018 Dickstein DL, Talty R, Bresnahan E, Varghese M, Perry B, Janssen WGM, Sowa A, Giedzinski E, Apodaca L, Baulch J, Acharya M, Parihar V, Limoli CL. Alterations in synaptic density and myelination in response to exposure to high-energy charged particles. The Journal of Comparative Neurology. PMID 30198564 DOI: 10.1002/cne.24530  0.36
2017 Varghese M, Keshav N, Jacot-Descombes S, Warda T, Wicinski B, Dickstein DL, Harony-Nicolas H, De Rubeis S, Drapeau E, Buxbaum JD, Hof PR. Autism spectrum disorder: neuropathology and animal models. Acta Neuropathologica. PMID 28584888 DOI: 10.1007/s00401-017-1736-4  0.56
2016 Dickstein DL, Dickstein DR, Janssen WG, Hof PR, Glaser JR, Rodriguez A, O'Connor N, Angstman P, Tappan SJ. Automatic Dendritic Spine Quantification from Confocal Data with Neurolucida 360. Current Protocols in Neuroscience. 77: 1.27.1-1.27.21. PMID 27696360 DOI: 10.1002/cpns.16  0.56
2016 Lazarczyk MJ, Kemmler JE, Eyford BA, Short JA, Varghese M, Sowa A, Dickstein DR, Yuk FJ, Puri R, Biron KE, Leist M, Jefferies WA, Dickstein DL. Major Histocompatibility Complex class I proteins are critical for maintaining neuronal structural complexity in the aging brain. Scientific Reports. 6: 26199. PMID 27229916 DOI: 10.1038/srep26199  0.36
2015 Brautigam H, Moreno CL, Steele JW, Bogush A, Dickstein DL, Kwok JB, Schofield PR, Thinakaran G, Mathews PM, Hof PR, Gandy S, Ehrlich ME. Physiologically generated presenilin 1 lacking exon 8 fails to rescue brain PS1-/- phenotype and forms complexes with wildtype PS1 and nicastrin. Scientific Reports. 5: 17042. PMID 26608390 DOI: 10.1038/srep17042  0.52
2015 Uppal N, Puri R, Yuk F, Janssen WG, Bozdagi-Gunal O, Harony-Nicolas H, Dickstein DL, Buxbaum JD, Hof PR. Ultrastructural analyses in the hippocampus CA1 field in Shank3-deficient mice. Molecular Autism. 6: 41. PMID 26137200 DOI: 10.1186/s13229-015-0036-x  0.52
2015 Elder GA, Gama Sosa MA, De Gasperi R, Stone JR, Dickstein DL, Haghighi F, Hof PR, Ahlers ST. Vascular and inflammatory factors in the pathophysiology of blast-induced brain injury. Frontiers in Neurology. 6: 48. PMID 25852632 DOI: 10.3389/fneur.2015.00048  0.52
2014 Price KA, Varghese M, Sowa A, Yuk F, Brautigam H, Ehrlich ME, Dickstein DL. Altered synaptic structure in the hippocampus in a mouse model of Alzheimer's disease with soluble amyloid-β oligomers and no plaque pathology. Molecular Neurodegeneration. 9: 41. PMID 25312309 DOI: 10.1186/1750-1326-9-41  0.52
2014 Gama Sosa MA, De Gasperi R, Janssen PL, Yuk FJ, Anazodo PC, Pricop PE, Paulino AJ, Wicinski B, Shaughness MC, Maudlin-Jeronimo E, Hall AA, Dickstein DL, McCarron RM, Chavko M, Hof PR, et al. Selective vulnerability of the cerebral vasculature to blast injury in a rat model of mild traumatic brain injury. Acta Neuropathologica Communications. 2: 67. PMID 24938728 DOI: 10.1186/2051-5960-2-67  0.52
2014 Steele JW, Brautigam H, Short JA, Sowa A, Shi M, Yadav A, Weaver CM, Westaway D, Fraser PE, St George-Hyslop PH, Gandy S, Hof PR, Dickstein DL. Early fear memory defects are associated with altered synaptic plasticity and molecular architecture in the TgCRND8 Alzheimer's disease mouse model. The Journal of Comparative Neurology. 522: 2319-35. PMID 24415002 DOI: 10.1002/cne.23536  0.52
2013 Brasnjevic I, Lardenoije R, Schmitz C, Van Der Kolk N, Dickstein DL, Takahashi H, Hof PR, Steinbusch HW, Rutten BP. REGION-SPECIFIC NEURON AND SYNAPSE LOSS IN THE HIPPOCAMPUS OF APP(SL)/PS1 KNOCK-IN MICE. Translational Neuroscience. 4: 8-19. PMID 24829793 DOI: 10.2478/s13380-013-0111-8  0.52
2013 Jefferies WA, Price KA, Biron KE, Fenninger F, Pfeifer CG, Dickstein DL. Adjusting the compass: new insights into the role of angiogenesis in Alzheimer's disease. Alzheimer's Research & Therapy. 5: 64. PMID 24351529 DOI: 10.1186/alzrt230  0.52
2013 Sosa MA, De Gasperi R, Paulino AJ, Pricop PE, Shaughness MC, Maudlin-Jeronimo E, Hall AA, Janssen WG, Yuk FJ, Dorr NP, Dickstein DL, McCarron RM, Chavko M, Hof PR, Ahlers ST, et al. Blast overpressure induces shear-related injuries in the brain of rats exposed to a mild traumatic brain injury. Acta Neuropathologica Communications. 1: 51. PMID 24252601 DOI: 10.1186/2051-5960-1-51  0.52
2013 Biron KE, Dickstein DL, Gopaul R, Fenninger F, Jefferies WA. Cessation of neoangiogenesis in Alzheimer's disease follows amyloid-beta immunization. Scientific Reports. 3: 1354. PMID 23446889 DOI: 10.1038/srep01354  0.68
2012 Brautigam H, Steele JW, Westaway D, Fraser PE, St George-Hyslop PH, Gandy S, Hof PR, Dickstein DL. The isotropic fractionator provides evidence for differential loss of hippocampal neurons in two mouse models of Alzheimer's disease. Molecular Neurodegeneration. 7: 58. PMID 23173713 DOI: 10.1186/1750-1326-7-58  0.52
2012 Tyan SH, Shih AY, Walsh JJ, Maruyama H, Sarsoza F, Ku L, Eggert S, Hof PR, Koo EH, Dickstein DL. Amyloid precursor protein (APP) regulates synaptic structure and function. Molecular and Cellular Neurosciences. 51: 43-52. PMID 22884903 DOI: 10.1016/j.mcn.2012.07.009  0.52
2012 Midthune B, Tyan SH, Walsh JJ, Sarsoza F, Eggert S, Hof PR, Dickstein DL, Koo EH. Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function. Molecular and Cellular Neurosciences. 49: 448-55. PMID 22353605 DOI: 10.1016/j.mcn.2012.02.001  0.52
2012 Yadav A, Gao YZ, Rodriguez A, Dickstein DL, Wearne SL, Luebke JI, Hof PR, Weaver CM. Morphologic evidence for spatially clustered spines in apical dendrites of monkey neocortical pyramidal cells. The Journal of Comparative Neurology. 520: 2888-902. PMID 22315181 DOI: 10.1002/cne.23070  0.52
2011 Biron KE, Dickstein DL, Gopaul R, Jefferies WA. Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease. Plos One. 6: e23789. PMID 21909359 DOI: 10.1371/journal.pone.0023789  0.68
2011 Wang J, Ono K, Dickstein DL, Arrieta-Cruz I, Zhao W, Qian X, Lamparello A, Subnani R, Ferruzzi M, Pavlides C, Ho L, Hof PR, Teplow DB, Pasinetti GM. Carvedilol as a potential novel agent for the treatment of Alzheimer's disease. Neurobiology of Aging. 32: 2321.e1-12. PMID 20579773 DOI: 10.1016/j.neurobiolaging.2010.05.004  0.52
2010 Bozdagi O, Sakurai T, Papapetrou D, Wang X, Dickstein DL, Takahashi N, Kajiwara Y, Yang M, Katz AM, Scattoni ML, Harris MJ, Saxena R, Silverman JL, Crawley JN, Zhou Q, et al. Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication. Molecular Autism. 1: 15. PMID 21167025 DOI: 10.1186/2040-2392-1-15  0.52
2010 Takahashi H, Brasnjevic I, Rutten BP, Van Der Kolk N, Perl DP, Bouras C, Steinbusch HW, Schmitz C, Hof PR, Dickstein DL. Hippocampal interneuron loss in an APP/PS1 double mutant mouse and in Alzheimer's disease. Brain Structure & Function. 214: 145-60. PMID 20213270 DOI: 10.1007/s00429-010-0242-4  0.56
2010 Dickstein DL, Brautigam H, Stockton SD, Schmeidler J, Hof PR. Changes in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau. Brain Structure & Function. 214: 161-79. PMID 20213269 DOI: 10.1007/s00429-010-0245-1  0.52
2010 Luebke JI, Weaver CM, Rocher AB, Rodriguez A, Crimins JL, Dickstein DL, Wearne SL, Hof PR. Dendritic vulnerability in neurodegenerative disease: insights from analyses of cortical pyramidal neurons in transgenic mouse models. Brain Structure & Function. 214: 181-99. PMID 20177698 DOI: 10.1007/s00429-010-0244-2  0.52
2010 Dickstein DL, Walsh J, Brautigam H, Stockton SD, Gandy S, Hof PR. Role of vascular risk factors and vascular dysfunction in Alzheimer's disease. The Mount Sinai Journal of Medicine, New York. 77: 82-102. PMID 20101718 DOI: 10.1002/msj.20155  0.52
2010 Gama Sosa MA, Gasperi RD, Rocher AB, Wang AC, Janssen WG, Flores T, Perez GM, Schmeidler J, Dickstein DL, Hof PR, Elder GA. Age-related vascular pathology in transgenic mice expressing presenilin 1-associated familial Alzheimer's disease mutations. The American Journal of Pathology. 176: 353-68. PMID 20008141 DOI: 10.2353/ajpath.2010.090482  0.52
2010 Elder GA, Gama Sosa MA, De Gasperi R, Dickstein DL, Hof PR. Presenilin transgenic mice as models of Alzheimer's disease. Brain Structure & Function. 214: 127-43. PMID 19921519 DOI: 10.1007/s00429-009-0227-3  0.56
2009 Franciosi S, Gama Sosa MA, English DF, Oler E, Oung T, Janssen WG, De Gasperi R, Schmeidler J, Dickstein DL, Schmitz C, Gandy S, Hof PR, Buxbaum JD, Elder GA. Novel cerebrovascular pathology in mice fed a high cholesterol diet. Molecular Neurodegeneration. 4: 42. PMID 19852847 DOI: 10.1186/1750-1326-4-42  0.52
2009 Pedrini S, Thomas C, Brautigam H, Schmeidler J, Ho L, Fraser P, Westaway D, Hyslop PS, Martins RN, Buxbaum JD, Pasinetti GM, Dickstein DL, Hof PR, Ehrlich ME, Gandy S. Dietary composition modulates brain mass and solubilizable Abeta levels in a mouse model of aggressive Alzheimer's amyloid pathology. Molecular Neurodegeneration. 4: 40. PMID 19845940 DOI: 10.1186/1750-1326-4-40  0.52
2009 Aslund A, Sigurdson CJ, Klingstedt T, Grathwohl S, Bolmont T, Dickstein DL, Glimsdal E, Prokop S, Lindgren M, Konradsson P, Holtzman DM, Hof PR, Heppner FL, Gandy S, Jucker M, et al. Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses. Acs Chemical Biology. 4: 673-84. PMID 19624097 DOI: 10.1021/cb900112v  0.52
2009 Ho L, Chen LH, Wang J, Zhao W, Talcott ST, Ono K, Teplow D, Humala N, Cheng A, Percival SS, Ferruzzi M, Janle E, Dickstein DL, Pasinetti GM. Heterogeneity in red wine polyphenolic contents differentially influences Alzheimer's disease-type neuropathology and cognitive deterioration. Journal of Alzheimer's Disease : Jad. 16: 59-72. PMID 19158422 DOI: 10.3233/JAD-2009-0916  0.52
2009 Brennan AR, Yuan P, Dickstein DL, Rocher AB, Hof PR, Manji H, Arnsten AF. Protein kinase C activity is associated with prefrontal cortical decline in aging. Neurobiology of Aging. 30: 782-92. PMID 17919783 DOI: 10.1016/j.neurobiolaging.2007.08.020  0.56
2008 Rodriguez A, Ehlenberger DB, Dickstein DL, Hof PR, Wearne SL. Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images. Plos One. 3: e1997. PMID 18431482 DOI: 10.1371/journal.pone.0001997  0.52
2007 Dickstein DL, Kabaso D, Rocher AB, Luebke JI, Wearne SL, Hof PR. Changes in the structural complexity of the aged brain. Aging Cell. 6: 275-84. PMID 17465981 DOI: 10.1111/j.1474-9726.2007.00289.x  0.52
2007 Franciosi S, De Gasperi R, Dickstein DL, English DF, Rocher AB, Janssen WG, Christoffel D, Sosa MA, Hof PR, Buxbaum JD, Elder GA. Pepsin pretreatment allows collagen IV immunostaining of blood vessels in adult mouse brain. Journal of Neuroscience Methods. 163: 76-82. PMID 17403541 DOI: 10.1016/j.jneumeth.2007.02.020  0.52
2006 Wang J, Ho L, Zhao Z, Seror I, Humala N, Dickstein DL, Thiyagarajan M, Percival SS, Talcott ST, Pasinetti GM. Moderate consumption of Cabernet Sauvignon attenuates Abeta neuropathology in a mouse model of Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2313-20. PMID 17077308 DOI: 10.1096/fj.06-6281com  0.52
2006 Dickstein DL, Biron KE, Ujiie M, Pfeifer CG, Jeffries AR, Jefferies WA. Abeta peptide immunization restores blood-brain barrier integrity in Alzheimer disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 426-33. PMID 16507760 DOI: 10.1096/fj.05-3956com  0.68
2003 Ujiie M, Dickstein DL, Carlow DA, Jefferies WA. Blood-brain barrier permeability precedes senile plaque formation in an Alzheimer disease model. Microcirculation (New York, N.Y. : 1994). 10: 463-70. PMID 14745459 DOI: 10.1038/sj.mn.7800212  0.68
2002 Ujiie M, Dickstein DL, Jefferies WA. p97 as a biomarker for Alzheimer disease. Frontiers in Bioscience : a Journal and Virtual Library. 7: e42-7. PMID 11815303  0.68
2001 Jefferies WA, Dickstein DL, Ujiie M. Assessing p97 as an Alzheimer's disease serum biomarker. Journal of Alzheimer's Disease : Jad. 3: 339-344. PMID 12214055  0.68
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