Dara L. Dickstein, Ph.D. - Publications

2005 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Neuroscience Biology, Pathology

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Perez Garcia G, De Gasperi R, Gama Sosa MA, Perez GM, Otero-Pagan A, Pryor D, Abutarboush R, Kawoos U, Hof PR, Dickstein DL, Cook DG, Gandy S, Ahlers ST, Elder GA. Laterality and region-specific tau phosphorylation correlate with PTSD-related behavioral traits in rats exposed to repetitive low-level blast. Acta Neuropathologica Communications. 9: 33. PMID 33648608 DOI: 10.1186/s40478-021-01128-3  0.412
2020 Jacot-Descombes S, Keshav NU, Dickstein DL, Wicinski B, Janssen WGM, Hiester LL, Sarfo EK, Warda T, Fam MM, Harony-Nicolas H, Buxbaum JD, Hof PR, Varghese M. Altered synaptic ultrastructure in the prefrontal cortex of Shank3-deficient rats. Molecular Autism. 11: 89. PMID 33203459 DOI: 10.1186/s13229-020-00393-8  0.7
2020 Dickstein DL, De Gasperi R, Gama Sosa MA, Perez-Garcia G, Short JA, Sosa H, Perez GM, Tschiffely AE, Dams-O'Connor K, Pullman MY, Knesaurek K, Knutsen A, Pham DL, Soleimani L, Jordan BD, et al. Brain and blood biomarkers of tauopathy and neuronal injury in humans and rats with neurobehavioral syndromes following blast exposure. Molecular Psychiatry. PMID 32094584 DOI: 10.1038/S41380-020-0674-Z  0.455
2019 Miller ML, Chadwick B, Dickstein DL, Purushothaman I, Egervari G, Rahman T, Tessereau C, Hof PR, Roussos P, Shen L, Baxter MG, Hurd YL. Cell- and layer-specific transcriptomic strategy for characterizing the molecular phenotype of rat cortical neurons using laser capture microdissection and massively parallel RNA sequencing. Molecular Psychiatry. 24: 473. PMID 30899095 DOI: 10.1038/S41380-019-0390-8  0.348
2018 Raghanti MA, Wicinski B, Meierovich R, Warda T, Dickstein DL, Reidenberg JS, Tang CY, George JC, Hans Thewissen JGM, Butti C, Hof PR. A comparison of the cortical structure of the bowhead whale (Balaena mysticetus), a basal mysticete, with other cetaceans. Anatomical Record (Hoboken, N.J. : 2007). PMID 30332717 DOI: 10.1002/Ar.23991  0.388
2018 Miller ML, Chadwick B, Dickstein DL, Purushothaman I, Egervari G, Rahman T, Tessereau C, Hof PR, Roussos P, Shen L, Baxter MG, Hurd YL. Adolescent exposure to Δ-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons. Molecular Psychiatry. PMID 30283037 DOI: 10.1038/S41380-018-0243-X  0.404
2018 Dickstein DL, Talty R, Bresnahan E, Varghese M, Perry B, Janssen WGM, Sowa A, Giedzinski E, Apodaca L, Baulch J, Acharya M, Parihar V, Limoli CL. Alterations in synaptic density and myelination in response to exposure to high-energy charged particles. The Journal of Comparative Neurology. PMID 30198564 DOI: 10.1002/Cne.24530  0.628
2017 Varghese M, Keshav N, Jacot-Descombes S, Warda T, Wicinski B, Dickstein DL, Harony-Nicolas H, De Rubeis S, Drapeau E, Buxbaum JD, Hof PR. Autism spectrum disorder: neuropathology and animal models. Acta Neuropathologica. PMID 28584888 DOI: 10.1007/S00401-017-1736-4  0.702
2017 Gandy S, Dickstein D, Pullman M, Short J, Kostakoglu L, Knesaurek K, Jordan B, Gordon W, Dams-O'Connor K, Tang C, Wong E, DeKosky S, Stone J, Farmer G, Peskind ER, et al. [P4-232]: TAU IMAGING WITH [18 F]T807/AV-1451 IN ATHLETES WITH POST-CONCUSSIVE COMPLAINT AND CONTROLS Alzheimer's & Dementia. 13: P1361-P1361. DOI: 10.1016/J.Jalz.2017.06.2100  0.415
2016 Dickstein DL, Dickstein DR, Janssen WG, Hof PR, Glaser JR, Rodriguez A, O'Connor N, Angstman P, Tappan SJ. Automatic Dendritic Spine Quantification from Confocal Data with Neurolucida 360. Current Protocols in Neuroscience. 77: 1.27.1-1.27.21. PMID 27696360 DOI: 10.1002/Cpns.16  0.484
2016 Dickstein DL, Pullman MY, Fernandez C, Short JA, Kostakoglu L, Knesaurek K, Soleimani L, Jordan BD, Gordon WA, Dams-O'Connor K, Delman BN, Wong E, Tang CY, DeKosky ST, Stone JR, et al. Cerebral [(18) F]T807/AV1451 retention pattern in clinically probable CTE resembles pathognomonic distribution of CTE tauopathy. Translational Psychiatry. 6: e900. PMID 27676441 DOI: 10.1038/Tp.2016.175  0.44
2016 Kajiwara Y, McKenzie A, Dorr N, Gama Sosa MA, Elder G, Schmeidler J, Dickstein DL, Bozdagi O, Zhang B, Buxbaum JD. The human-specific CASP4 gene contributes to Alzheimer-related synaptic and behavioral deficits. Human Molecular Genetics. PMID 27516385 DOI: 10.1093/Hmg/Ddw265  0.463
2016 Lazarczyk MJ, Kemmler JE, Eyford BA, Short JA, Varghese M, Sowa A, Dickstein DR, Yuk FJ, Puri R, Biron KE, Leist M, Jefferies WA, Dickstein DL. Major Histocompatibility Complex class I proteins are critical for maintaining neuronal structural complexity in the aging brain. Scientific Reports. 6: 26199. PMID 27229916 DOI: 10.1038/Srep26199  0.763
2015 Brautigam H, Moreno CL, Steele JW, Bogush A, Dickstein DL, Kwok JB, Schofield PR, Thinakaran G, Mathews PM, Hof PR, Gandy S, Ehrlich ME. Physiologically generated presenilin 1 lacking exon 8 fails to rescue brain PS1-/- phenotype and forms complexes with wildtype PS1 and nicastrin. Scientific Reports. 5: 17042. PMID 26608390 DOI: 10.1038/Srep17042  0.505
2015 Uppal N, Puri R, Yuk F, Janssen WG, Bozdagi-Gunal O, Harony-Nicolas H, Dickstein DL, Buxbaum JD, Hof PR. Ultrastructural analyses in the hippocampus CA1 field in Shank3-deficient mice. Molecular Autism. 6: 41. PMID 26137200 DOI: 10.1186/S13229-015-0036-X  0.527
2015 Elder GA, Gama Sosa MA, De Gasperi R, Stone JR, Dickstein DL, Haghighi F, Hof PR, Ahlers ST. Vascular and inflammatory factors in the pathophysiology of blast-induced brain injury. Frontiers in Neurology. 6: 48. PMID 25852632 DOI: 10.3389/Fneur.2015.00048  0.488
2015 Wang J, Dickstein D, Hof P, Pasinetti GM. P2-315: Preservation of synaptic plasticity and neuronal integrity in a mouse model of Alzheimer's disease Alzheimer's & Dementia. 11: P614-P614. DOI: 10.1016/J.Jalz.2015.06.857  0.665
2014 Price KA, Varghese M, Sowa A, Yuk F, Brautigam H, Ehrlich ME, Dickstein DL. Altered synaptic structure in the hippocampus in a mouse model of Alzheimer's disease with soluble amyloid-β oligomers and no plaque pathology. Molecular Neurodegeneration. 9: 41. PMID 25312309 DOI: 10.1186/1750-1326-9-41  0.757
2014 Mitsis EM, Riggio S, Kostakoglu L, Dickstein DL, Machac J, Delman B, Goldstein M, Jennings D, D'Antonio E, Martin J, Naidich TP, Aloysi A, Fernandez C, Seibyl J, DeKosky ST, et al. Tauopathy PET and amyloid PET in the diagnosis of chronic traumatic encephalopathies: studies of a retired NFL player and of a man with FTD and a severe head injury. Translational Psychiatry. 4: e441. PMID 25226550 DOI: 10.1038/Tp.2014.91  0.473
2014 Gama Sosa MA, De Gasperi R, Janssen PL, Yuk FJ, Anazodo PC, Pricop PE, Paulino AJ, Wicinski B, Shaughness MC, Maudlin-Jeronimo E, Hall AA, Dickstein DL, McCarron RM, Chavko M, Hof PR, et al. Selective vulnerability of the cerebral vasculature to blast injury in a rat model of mild traumatic brain injury. Acta Neuropathologica Communications. 2: 67. PMID 24938728 DOI: 10.1186/2051-5960-2-67  0.46
2014 Steele JW, Brautigam H, Short JA, Sowa A, Shi M, Yadav A, Weaver CM, Westaway D, Fraser PE, St George-Hyslop PH, Gandy S, Hof PR, Dickstein DL. Early fear memory defects are associated with altered synaptic plasticity and molecular architecture in the TgCRND8 Alzheimer's disease mouse model. The Journal of Comparative Neurology. 522: 2319-35. PMID 24415002 DOI: 10.1002/Cne.23536  0.618
2013 Brasnjevic I, Lardenoije R, Schmitz C, Van Der Kolk N, Dickstein DL, Takahashi H, Hof PR, Steinbusch HW, Rutten BP. REGION-SPECIFIC NEURON AND SYNAPSE LOSS IN THE HIPPOCAMPUS OF APP(SL)/PS1 KNOCK-IN MICE. Translational Neuroscience. 4: 8-19. PMID 24829793 DOI: 10.2478/S13380-013-0111-8  0.575
2013 Jefferies WA, Price KA, Biron KE, Fenninger F, Pfeifer CG, Dickstein DL. Adjusting the compass: new insights into the role of angiogenesis in Alzheimer's disease. Alzheimer's Research & Therapy. 5: 64. PMID 24351529 DOI: 10.1186/Alzrt230  0.689
2013 Sosa MA, De Gasperi R, Paulino AJ, Pricop PE, Shaughness MC, Maudlin-Jeronimo E, Hall AA, Janssen WG, Yuk FJ, Dorr NP, Dickstein DL, McCarron RM, Chavko M, Hof PR, Ahlers ST, et al. Blast overpressure induces shear-related injuries in the brain of rats exposed to a mild traumatic brain injury. Acta Neuropathologica Communications. 1: 51. PMID 24252601 DOI: 10.1186/2051-5960-1-51  0.446
2013 Biron KE, Dickstein DL, Gopaul R, Fenninger F, Jefferies WA. Cessation of neoangiogenesis in Alzheimer's disease follows amyloid-beta immunization. Scientific Reports. 3: 1354. PMID 23446889 DOI: 10.1038/Srep01354  0.689
2013 Dickstein DL, Weaver CM, Luebke JI, Hof PR. Dendritic spine changes associated with normal aging. Neuroscience. 251: 21-32. PMID 23069756 DOI: 10.1016/J.Neuroscience.2012.09.077  0.479
2013 Wu J, Dickstein D, Duff K. Mechanism of tau transfer: insights from cell culture and animal models Molecular Neurodegeneration. 8: P50. DOI: 10.1186/1750-1326-8-S1-P50  0.382
2012 Brautigam H, Steele JW, Westaway D, Fraser PE, St George-Hyslop PH, Gandy S, Hof PR, Dickstein DL. The isotropic fractionator provides evidence for differential loss of hippocampal neurons in two mouse models of Alzheimer's disease. Molecular Neurodegeneration. 7: 58. PMID 23173713 DOI: 10.1186/1750-1326-7-58  0.605
2012 Tyan SH, Shih AY, Walsh JJ, Maruyama H, Sarsoza F, Ku L, Eggert S, Hof PR, Koo EH, Dickstein DL. Amyloid precursor protein (APP) regulates synaptic structure and function. Molecular and Cellular Neurosciences. 51: 43-52. PMID 22884903 DOI: 10.1016/J.Mcn.2012.07.009  0.621
2012 Midthune B, Tyan SH, Walsh JJ, Sarsoza F, Eggert S, Hof PR, Dickstein DL, Koo EH. Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function. Molecular and Cellular Neurosciences. 49: 448-55. PMID 22353605 DOI: 10.1016/J.Mcn.2012.02.001  0.557
2012 Yadav A, Gao YZ, Rodriguez A, Dickstein DL, Wearne SL, Luebke JI, Hof PR, Weaver CM. Morphologic evidence for spatially clustered spines in apical dendrites of monkey neocortical pyramidal cells. The Journal of Comparative Neurology. 520: 2888-902. PMID 22315181 DOI: 10.1002/Cne.23070  0.444
2011 Biron KE, Dickstein DL, Gopaul R, Jefferies WA. Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease. Plos One. 6: e23789. PMID 21909359 DOI: 10.1371/Journal.Pone.0023789  0.697
2011 Wang J, Ono K, Dickstein DL, Arrieta-Cruz I, Zhao W, Qian X, Lamparello A, Subnani R, Ferruzzi M, Pavlides C, Ho L, Hof PR, Teplow DB, Pasinetti GM. Carvedilol as a potential novel agent for the treatment of Alzheimer's disease. Neurobiology of Aging. 32: 2321.e1-12. PMID 20579773 DOI: 10.1016/J.Neurobiolaging.2010.05.004  0.683
2011 Bloss EB, Morrison JH, Hof PR, Dickstein DL. Influence of aging and neurodegeneration on dendritic spine morphology Translational Neuroscience. 2: 49-60. DOI: 10.2478/S13380-011-0008-3  0.541
2010 Bozdagi O, Sakurai T, Papapetrou D, Wang X, Dickstein DL, Takahashi N, Kajiwara Y, Yang M, Katz AM, Scattoni ML, Harris MJ, Saxena R, Silverman JL, Crawley JN, Zhou Q, et al. Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication. Molecular Autism. 1: 15. PMID 21167025 DOI: 10.1186/2040-2392-1-15  0.46
2010 Takahashi H, Brasnjevic I, Rutten BP, Van Der Kolk N, Perl DP, Bouras C, Steinbusch HW, Schmitz C, Hof PR, Dickstein DL. Hippocampal interneuron loss in an APP/PS1 double mutant mouse and in Alzheimer's disease. Brain Structure & Function. 214: 145-60. PMID 20213270 DOI: 10.1007/S00429-010-0242-4  0.586
2010 Dickstein DL, Brautigam H, Stockton SD, Schmeidler J, Hof PR. Changes in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau. Brain Structure & Function. 214: 161-79. PMID 20213269 DOI: 10.1007/S00429-010-0245-1  0.601
2010 Luebke JI, Weaver CM, Rocher AB, Rodriguez A, Crimins JL, Dickstein DL, Wearne SL, Hof PR. Dendritic vulnerability in neurodegenerative disease: insights from analyses of cortical pyramidal neurons in transgenic mouse models. Brain Structure & Function. 214: 181-99. PMID 20177698 DOI: 10.1007/S00429-010-0244-2  0.578
2010 Dickstein DL, Walsh J, Brautigam H, Stockton SD, Gandy S, Hof PR. Role of vascular risk factors and vascular dysfunction in Alzheimer's disease. The Mount Sinai Journal of Medicine, New York. 77: 82-102. PMID 20101718 DOI: 10.1002/Msj.20155  0.51
2010 Gama Sosa MA, Gasperi RD, Rocher AB, Wang AC, Janssen WG, Flores T, Perez GM, Schmeidler J, Dickstein DL, Hof PR, Elder GA. Age-related vascular pathology in transgenic mice expressing presenilin 1-associated familial Alzheimer's disease mutations. The American Journal of Pathology. 176: 353-68. PMID 20008141 DOI: 10.2353/Ajpath.2010.090482  0.555
2010 Elder GA, Gama Sosa MA, De Gasperi R, Dickstein DL, Hof PR. Presenilin transgenic mice as models of Alzheimer's disease. Brain Structure & Function. 214: 127-43. PMID 19921519 DOI: 10.1007/S00429-009-0227-3  0.574
2010 Dickstein DL, Morrison JH, Hof PR. Neuropathology of Aging Imaging the Aging Brain. DOI: 10.1093/acprof:oso/9780195328875.003.0003  0.34
2010 Brautigam H, Klingstedt T, Prokop S, Holtzman DM, Heppner FL, Haroutunian V, Dickstein DL, Hof PR, Nilsson PR, Gandy S. O4-08-06: New Conformation-Sensing Imaging Compounds Distinguish Protein Deposits In Apoe ε3/ε3 Alzheimer's Patients From that in Apoe ε4/ε4 Alzheimer's Patients Alzheimer's & Dementia. 6: e19-e20. DOI: 10.1016/J.Jalz.2010.08.059  0.473
2010 Walsh JJ, Tyan S, Midthune B, Yu-Jung Shih A, Eggert S, Hof PR, Koo E, Dickstein DL. P1-135: Comparison of neuronal morphology in pyramidal neurons of the CA1, dentate gyrus, and prefrontal cortex of APP knockout and APLP2 knockout mice Alzheimer's & Dementia. 6: S213-S213. DOI: 10.1016/J.Jalz.2010.05.684  0.5
2010 Dickstein DL, Rodriguez A, Rocher AB, Wearne SL, Luebke JI, Weaver CM, Hof PR. P2-331: NeuronStudio: An automated quantitative software to assess changes in spine pathology in Alzheimer models Alzheimer's & Dementia. 6: S410-S410. DOI: 10.1016/J.Jalz.2010.05.1382  0.492
2010 Tyan S, Midthune B, Eggert S, Dickstein DL, Koo EH. P2-328: Role of amyloid precursor proteins and beta-amyloid-induced synaptic dysfunction Alzheimer's & Dementia. 6: S409-S409. DOI: 10.1016/J.Jalz.2010.05.1379  0.386
2009 Franciosi S, Gama Sosa MA, English DF, Oler E, Oung T, Janssen WG, De Gasperi R, Schmeidler J, Dickstein DL, Schmitz C, Gandy S, Hof PR, Buxbaum JD, Elder GA. Novel cerebrovascular pathology in mice fed a high cholesterol diet. Molecular Neurodegeneration. 4: 42. PMID 19852847 DOI: 10.1186/1750-1326-4-42  0.445
2009 Pedrini S, Thomas C, Brautigam H, Schmeidler J, Ho L, Fraser P, Westaway D, Hyslop PS, Martins RN, Buxbaum JD, Pasinetti GM, Dickstein DL, Hof PR, Ehrlich ME, Gandy S. Dietary composition modulates brain mass and solubilizable Abeta levels in a mouse model of aggressive Alzheimer's amyloid pathology. Molecular Neurodegeneration. 4: 40. PMID 19845940 DOI: 10.1186/1750-1326-4-40  0.671
2009 Aslund A, Sigurdson CJ, Klingstedt T, Grathwohl S, Bolmont T, Dickstein DL, Glimsdal E, Prokop S, Lindgren M, Konradsson P, Holtzman DM, Hof PR, Heppner FL, Gandy S, Jucker M, et al. Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses. Acs Chemical Biology. 4: 673-84. PMID 19624097 DOI: 10.1021/Cb900112V  0.522
2009 Ho L, Chen LH, Wang J, Zhao W, Talcott ST, Ono K, Teplow D, Humala N, Cheng A, Percival SS, Ferruzzi M, Janle E, Dickstein DL, Pasinetti GM. Heterogeneity in red wine polyphenolic contents differentially influences Alzheimer's disease-type neuropathology and cognitive deterioration. Journal of Alzheimer's Disease : Jad. 16: 59-72. PMID 19158422 DOI: 10.3233/Jad-2009-0916  0.605
2009 Brennan AR, Yuan P, Dickstein DL, Rocher AB, Hof PR, Manji H, Arnsten AF. Protein kinase C activity is associated with prefrontal cortical decline in aging. Neurobiology of Aging. 30: 782-92. PMID 17919783 DOI: 10.1016/J.Neurobiolaging.2007.08.020  0.458
2008 Rodriguez A, Ehlenberger DB, Dickstein DL, Hof PR, Wearne SL. Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images. Plos One. 3: e1997. PMID 18431482 DOI: 10.1371/Journal.Pone.0001997  0.472
2008 Stockton SD, Dickstein DL, Christoffel D, Hof PR. P1-112: Hippocampal cell loss in the HTAU mouse model during disease progression Alzheimer's & Dementia. 4: T239-T240. DOI: 10.1016/J.Jalz.2008.05.699  0.481
2008 Dickstein DL, Hof PR. P1-057: Dendritic alterations in layer II/III pyramidal neurons in the frontal cortex of HTAU mice during disease progression Alzheimer's & Dementia. 4: T222-T222. DOI: 10.1016/J.Jalz.2008.05.643  0.504
2007 Dickstein DL, Kabaso D, Rocher AB, Luebke JI, Wearne SL, Hof PR. Changes in the structural complexity of the aged brain. Aging Cell. 6: 275-84. PMID 17465981 DOI: 10.1111/J.1474-9726.2007.00289.X  0.548
2007 Franciosi S, De Gasperi R, Dickstein DL, English DF, Rocher AB, Janssen WG, Christoffel D, Sosa MA, Hof PR, Buxbaum JD, Elder GA. Pepsin pretreatment allows collagen IV immunostaining of blood vessels in adult mouse brain. Journal of Neuroscience Methods. 163: 76-82. PMID 17403541 DOI: 10.1016/J.Jneumeth.2007.02.020  0.467
2006 Wang J, Ho L, Zhao Z, Seror I, Humala N, Dickstein DL, Thiyagarajan M, Percival SS, Talcott ST, Pasinetti GM. Moderate consumption of Cabernet Sauvignon attenuates Abeta neuropathology in a mouse model of Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2313-20. PMID 17077308 DOI: 10.1096/Fj.06-6281Com  0.601
2006 Dickstein DL, Biron KE, Ujiie M, Pfeifer CG, Jeffries AR, Jefferies WA. Abeta peptide immunization restores blood-brain barrier integrity in Alzheimer disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 426-33. PMID 16507760 DOI: 10.1096/Fj.05-3956Com  0.674
2006 Dickstein DL, Janssen WG, Rocher AB, Flores T, Senturk E, DeGasperi R, Elder GA, Gama-Sosa MA, Hof PR. P1-065: Neuronal degeneration in transgenic mice expressing the entire transcript unit of mutant presenilin 1 Alzheimer's & Dementia. 2: S113-S114. DOI: 10.1016/J.Jalz.2006.05.440  0.487
2004 Dickstein DL, Jeffries AR, Jefferies WA. P4-378 The effect of a-beta immunization on blood-brain barrier integrity in the TG2576 AD model mouse Neurobiology of Aging. 25: S582. DOI: 10.1016/S0197-4580(04)81936-5  0.644
2003 Ujiie M, Dickstein DL, Carlow DA, Jefferies WA. Blood-brain barrier permeability precedes senile plaque formation in an Alzheimer disease model. Microcirculation (New York, N.Y. : 1994). 10: 463-70. PMID 14745459 DOI: 10.1038/Sj.Mn.7800212  0.686
2002 Ujiie M, Dickstein DL, Jefferies WA. p97 as a biomarker for Alzheimer disease. Frontiers in Bioscience : a Journal and Virtual Library. 7: e42-7. PMID 11815303 DOI: 10.2741/Ujiie  0.659
2001 Jefferies WA, Dickstein DL, Ujiie M. Assessing p97 as an Alzheimer's disease serum biomarker. Journal of Alzheimer's Disease : Jad. 3: 339-344. PMID 12214055 DOI: 10.3233/Jad-2001-3309  0.658
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