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David R. McMillen, Ph.D. - Publications

Affiliations: 
2000 University of Toronto, Toronto, ON, Canada 
Area:
General Biophysics, Aerospace Engineering
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Hussey BJ, McMillen DR. Programmable T7-based synthetic transcription factors. Nucleic Acids Research. PMID 30169636 DOI: 10.1093/Nar/Gky785  0.331
2016 Harris EA, Buzina A, Moffat J, McMillen DR. Design and experimental validation of small activating RNAs targeting an exogenous promoter in human cells. Acs Synthetic Biology. PMID 28033709 DOI: 10.1021/Acssynbio.6B00125  0.304
2016 Tang ZF, McMillen DR. Design principles for the analysis and construction of robustly homeostatic biological networks. Journal of Theoretical Biology. PMID 27378006 DOI: 10.1016/J.Jtbi.2016.06.036  0.451
2016 Harris EA, Koh EJ, Moffat J, McMillen DR. Automated inference procedure for the determination of cell growth parameters. Physical Review. E. 93: 012402. PMID 26871096 DOI: 10.1103/Physreve.93.012402  0.309
2015 Mazumder M, Brechun KE, Kim YB, Hoffmann SA, Chen YY, Keiski CL, Arndt KM, McMillen DR, Woolley GA. An Escherichia coli system for evolving improved light-controlled DNA-binding proteins. Protein Engineering, Design & Selection : Peds. 28: 293-302. PMID 26245690 DOI: 10.1093/Protein/Gzv033  0.618
2014 Mazumder M, McMillen DR. Design and characterization of a dual-mode promoter with activation and repression capability for tuning gene expression in yeast. Nucleic Acids Research. 42: 9514-22. PMID 25056312 DOI: 10.1093/Nar/Gku651  0.685
2013 Ang J, Harris E, Hussey BJ, Kil R, McMillen DR. Tuning response curves for synthetic biology. Acs Synthetic Biology. 2: 547-67. PMID 23905721 DOI: 10.1021/Sb4000564  0.727
2013 Ang J, McMillen DR. Physical constraints on biological integral control design for homeostasis and sensory adaptation. Biophysical Journal. 104: 505-15. PMID 23442873 DOI: 10.1016/J.Bpj.2012.12.015  0.735
2011 Ang J, Ingalls B, McMillen D. Probing the input-output behavior of biochemical and genetic systems system identification methods from control theory. Methods in Enzymology. 487: 279-317. PMID 21187229 DOI: 10.1016/B978-0-12-381270-4.00010-X  0.732
2011 Bagh S, Mandal M, Ang J, McMillen DR. An active intracellular device to prevent lethal disease outcomes in virus-infected bacterial cells. Biotechnology and Bioengineering. 108: 645-54. PMID 20967799 DOI: 10.1002/Bit.22969  0.695
2010 Bagh S, Mandal M, McMillen DR. Minimal genetic device with multiple tunable functions. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 82: 021911. PMID 20866841 DOI: 10.1103/Physreve.82.021911  0.395
2010 Ang J, Bagh S, Ingalls BP, McMillen DR. Considerations for using integral feedback control to construct a perfectly adapting synthetic gene network. Journal of Theoretical Biology. 266: 723-38. PMID 20688080 DOI: 10.1016/J.Jtbi.2010.07.034  0.729
2009 Bagh S, McMillen DR. A synthetic genetic circuit whose signal-response curve is temperature-tunable from band-detection to sigmoidal behaviour Natural Computing. 9: 991-1006. DOI: 10.1007/S11047-009-9167-3  0.386
2008 Iafolla MA, Dong GQ, McMillen DR. Increasing the efficiency of bacterial transcription simulations: when to exclude the genome without loss of accuracy. Bmc Bioinformatics. 9: 373. PMID 18789148 DOI: 10.1186/1471-2105-9-373  0.316
2008 Bagh S, Mazumder M, Velauthapillai T, Sardana V, Dong GQ, Movva AB, Lim LH, McMillen DR. Plasmid-borne prokaryotic gene expression: sources of variability and quantitative system characterization. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 77: 021919. PMID 18352063 DOI: 10.1103/Physreve.77.021919  0.67
2008 Dong GQ, McMillen DR. Effects of protein maturation on the noise in gene expression. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 77: 021908. PMID 18352052 DOI: 10.1103/Physreve.77.021908  0.34
2008 Iafolla MA, Mazumder M, Sardana V, Velauthapillai T, Pannu K, McMillen DR. Dark proteins: effect of inclusion body formation on quantification of protein expression. Proteins. 72: 1233-42. PMID 18350571 DOI: 10.1002/Prot.22024  0.645
2007 Dong GQ, Jakobowski L, Iafolla MA, McMillen DR. Simplification of stochastic chemical reaction models with fast and slow dynamics. Journal of Biological Physics. 33: 67-95. PMID 19669554 DOI: 10.1007/S10867-007-9043-2  0.376
2006 Dong CG, Jakobowski L, McMillen DR. Systematic reduction of a stochastic signalling cascade model. Journal of Biological Physics. 32: 173-6. PMID 19669460 DOI: 10.1007/S10867-006-9005-0  0.365
2006 Iafolla MA, McMillen DR. Extracting biochemical parameters for cellular modeling: A mean-field approach. The Journal of Physical Chemistry. B. 110: 22019-28. PMID 17064172 DOI: 10.1021/Jp062739M  0.337
2006 Guido NJ, Wang X, Adalsteinsson D, McMillen D, Hasty J, Cantor CR, Elston TC, Collins JJ. A bottom-up approach to gene regulation. Nature. 439: 856-60. PMID 16482159 DOI: 10.1038/Nature04473  0.431
2004 Adalsteinsson D, McMillen D, Elston TC. Biochemical Network Stochastic Simulator (BioNetS): software for stochastic modeling of biochemical networks. Bmc Bioinformatics. 5: 24. PMID 15113411 DOI: 10.1186/1471-2105-5-24  0.379
2003 McMillen D, Kopell N. Noise-stabilized long-distance synchronization in populations of model neurons. Journal of Computational Neuroscience. 15: 143-57. PMID 14512745 DOI: 10.1023/A:1025860724292  0.325
2002 Hasty J, McMillen D, Collins JJ. Engineered gene circuits. Nature. 420: 224-30. PMID 12432407 DOI: 10.1038/Nature01257  0.437
2002 McMillen D, Kopell N, Hasty J, Collins JJ. Synchronizing genetic relaxation oscillators by intercell signaling. Proceedings of the National Academy of Sciences of the United States of America. 99: 679-84. PMID 11805323 DOI: 10.1073/Pnas.022642299  0.398
2001 Hasty J, Isaacs F, Dolnik M, McMillen D, Collins JJ. Designer gene networks: Towards fundamental cellular control. Chaos (Woodbury, N.Y.). 11: 207-220. PMID 12779454 DOI: 10.1063/1.1345702  0.455
2001 Hasty J, McMillen D, Isaacs F, Collins JJ. Computational studies of gene regulatory networks: in numero molecular biology. Nature Reviews. Genetics. 2: 268-79. PMID 11283699 DOI: 10.1038/35066056  0.374
1999 McMillen DR, D'Eleuterio GM, Halperin JR. Simple central pattern generator model using phasic analog neurons. Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics. 59: 6994-9. PMID 11969687 DOI: 10.1103/Physreve.59.6994  0.66
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