cached image

Dirk Görlich, Ph.D. - Publications

Affiliations: 
Max Planck Institute for Biophysical Chemistry, Göttingen, Göttingen, Niedersachsen, Germany 
Area:
Nuclear Pore
Website:
http://www.uni-goettingen.de/en/57954.html

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 García-García M, Sánchez-Perales S, Jarabo P, Calvo E, Huyton T, Fu L, Ng SC, Sotodosos-Alonso L, Vázquez J, Casas-Tintó S, Görlich D, Echarri A, Del Pozo MA. Mechanical control of nuclear import by Importin-7 is regulated by its dominant cargo YAP. Nature Communications. 13: 1174. PMID 35246520 DOI: 10.1038/s41467-022-28693-y  0.307
2019 Vera Rodriguez A, Frey S, Görlich D. Engineered SUMO/protease system identifies Pdr6 as a bidirectional nuclear transport receptor. The Journal of Cell Biology. PMID 31023724 DOI: 10.1083/jcb.201812091  0.339
2019 Aksu M, Trakhanov S, Vera Rodriguez A, Görlich D. Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122. The Journal of Cell Biology. PMID 31023722 DOI: 10.1083/jcb.201812093  0.323
2018 Aksu M, Pleiner T, Karaca S, Kappert C, Dehne HJ, Seibel K, Urlaub H, Bohnsack MT, Görlich D. Xpo7 is a broad-spectrum exportin and a nuclear import receptor. The Journal of Cell Biology. PMID 29748336 DOI: 10.1083/jcb.201712013  0.326
2018 Ananth AN, Mishra A, Frey S, Dwarkasing A, Versloot R, van der Giessen E, Görlich D, Onck P, Dekker C. Spatial structure of disordered proteins dictates conductance and selectivity in Nuclear Pore Complex mimics. Elife. 7. PMID 29442997 DOI: 10.7554/Elife.31510  0.33
2016 Aksu M, Trakhanov S, Görlich D. Structure of the exportin Xpo4 in complex with RanGTP and the hypusine-containing translation factor eIF5A. Nature Communications. 7: 11952. PMID 27306458 DOI: 10.1038/ncomms11952  0.348
2016 Schmidt HB, Görlich D. Transport Selectivity of Nuclear Pores, Phase Separation, and Membraneless Organelles. Trends in Biochemical Sciences. 41: 46-61. PMID 26705895 DOI: 10.1016/j.tibs.2015.11.001  0.333
2015 Kirli K, Karaca S, Dehne HJ, Samwer M, Pan KT, Lenz C, Urlaub H, Görlich D. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife. 4. PMID 26673895 DOI: 10.7554/eLife.11466  0.311
2015 Frey S, Görlich D. The Xenopus laevis Atg4B Protease: Insights into Substrate Recognition and Application for Tag Removal from Proteins Expressed in Pro- and Eukaryotic Hosts. Plos One. 10: e0125099. PMID 25923686 DOI: 10.1371/journal.pone.0125099  0.312
2014 Hattangadi SM, Martinez-Morilla S, Patterson HC, Shi J, Burke K, Avila-Figueroa A, Venkatesan S, Wang J, Paulsen K, Görlich D, Murata-Hori M, Lodish HF. Histones to the cytosol: exportin 7 is essential for normal terminal erythroid nuclear maturation. Blood. 124: 1931-40. PMID 25092175 DOI: 10.1182/Blood-2013-11-537761  0.336
2012 Hülsmann BB, Labokha AA, Görlich D. The permeability of reconstituted nuclear pores provides direct evidence for the selective phase model. Cell. 150: 738-51. PMID 22901806 DOI: 10.1016/j.cell.2012.07.019  0.317
2011 Güttler T, Görlich D. Ran-dependent nuclear export mediators: a structural perspective. The Embo Journal. 30: 3457-74. PMID 21878989 DOI: 10.1038/emboj.2011.287  0.403
2010 Ader C, Frey S, Maas W, Schmidt HB, Görlich D, Baldus M. Amyloid-like interactions within nucleoporin FG hydrogels. Proceedings of the National Academy of Sciences of the United States of America. 107: 6281-5. PMID 20304795 DOI: 10.1073/Pnas.0910163107  0.36
2009 Monecke T, Güttler T, Neumann P, Dickmanns A, Görlich D, Ficner R. Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP. Science (New York, N.Y.). 324: 1087-91. PMID 19389996 DOI: 10.1126/science.1173388  0.332
2007 Frey S, Görlich D. A saturated FG-repeat hydrogel can reproduce the permeability properties of nuclear pore complexes. Cell. 130: 512-23. PMID 17693259 DOI: 10.1016/j.cell.2007.06.024  0.414
2006 Frey S, Richter RP, Görlich D. FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties. Science (New York, N.Y.). 314: 815-7. PMID 17082456 DOI: 10.1126/science.1132516  0.365
2004 Mingot JM, Bohnsack MT, Jäkle U, Görlich D. Exportin 7 defines a novel general nuclear export pathway. The Embo Journal. 23: 3227-36. PMID 15282546 DOI: 10.1038/sj.emboj.7600338  0.406
2003 Stüven T, Hartmann E, Görlich D. Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes. The Embo Journal. 22: 5928-40. PMID 14592989 DOI: 10.1093/emboj/cdg565  0.375
2003 Görlich D, Seewald MJ, Ribbeck K. Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation. The Embo Journal. 22: 1088-100. PMID 12606574 DOI: 10.1093/emboj/cdg113  0.324
2002 Bohnsack MT, Regener K, Schwappach B, Saffrich R, Paraskeva E, Hartmann E, Görlich D. Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. The Embo Journal. 21: 6205-15. PMID 12426392 DOI: 10.1093/emboj/cdf613  0.417
2002 Ribbeck K, Görlich D. The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion. The Embo Journal. 21: 2664-71. PMID 12032079 DOI: 10.1093/emboj/21.11.2664  0.355
2002 Jäkel S, Mingot JM, Schwarzmaier P, Hartmann E, Görlich D. Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. The Embo Journal. 21: 377-86. PMID 11823430 DOI: 10.1093/emboj/21.3.377  0.448
2001 Köhler M, Görlich D, Hartmann E, Franke J. Adenoviral E1A protein nuclear import is preferentially mediated by importin alpha3 in vitro. Virology. 289: 186-91. PMID 11689041 DOI: 10.1006/viro.2001.1151  0.312
2001 Dean KA, von Ahsen O, Görlich D, Fried HM. Signal recognition particle protein 19 is imported into the nucleus by importin 8 (RanBP8) and transportin. Journal of Cell Science. 114: 3479-85. PMID 11682607  0.463
2001 Mingot JM, Kostka S, Kraft R, Hartmann E, Görlich D. Importin 13: a novel mediator of nuclear import and export. The Embo Journal. 20: 3685-94. PMID 11447110 DOI: 10.1093/emboj/20.14.3685  0.475
2001 Ferrando-May E, Cordes V, Biller-Ckovric I, Mirkovic J, Görlich D, Nicotera P. Caspases mediate nucleoporin cleavage, but not early redistribution of nuclear transport factors and modulation of nuclear permeability in apoptosis. Cell Death and Differentiation. 8: 495-505. PMID 11423910 DOI: 10.1038/sj.cdd.4400837  0.347
2001 Ribbeck K, Görlich D. Kinetic analysis of translocation through nuclear pore complexes. The Embo Journal. 20: 1320-30. PMID 11250898 DOI: 10.1093/emboj/20.6.1320  0.317
2000 Kutay U, Hartmann E, Treichel N, Calado A, Carmo-Fonseca M, Prehn S, Kraft R, Gorlich D, Bischoff FR. Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily. The Journal of Biological Chemistry. 275: 40163-8. PMID 11024021 DOI: 10.1074/Jbc.M006242200  0.77
2000 Villa Braslavsky CI, Nowak C, Görlich D, Wittinghofer A, Kuhlmann J. Different structural and kinetic requirements for the interaction of Ran with the Ran-binding domains from RanBP2 and importin-beta. Biochemistry. 39: 11629-39. PMID 10995230 DOI: 10.1021/bi001010f  0.453
2000 Lipowsky G, Bischoff FR, Schwarzmaier P, Kraft R, Kostka S, Hartmann E, Kutay U, Görlich D. Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes. The Embo Journal. 19: 4362-71. PMID 10944119 DOI: 10.1093/Emboj/19.16.4362  0.741
2000 Bannister AJ, Miska EA, Görlich D, Kouzarides T. Acetylation of importin-alpha nuclear import factors by CBP/p300. Current Biology : Cb. 10: 467-70. PMID 10801418 DOI: 10.1016/S0960-9822(00)00445-0  0.404
2000 Bachi A, Braun IC, Rodrigues JP, Panté N, Ribbeck K, von Kobbe C, Kutay U, Wilm M, Görlich D, Carmo-Fonseca M, Izaurralde E. The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates. Rna (New York, N.Y.). 6: 136-58. PMID 10668806 DOI: 10.1017/S1355838200991994  0.762
2000 Vetter IR, Nowak C, Nishimoto T, Kuhlmann J, Arndt A, Kutay U, Görlich D, Wittinghofer A. Novel types of interactions of the small GTPase Ran with its effectors Acta Crystallographica Section a Foundations of Crystallography. 56: s101-s101. DOI: 10.1107/S0108767300022716  0.664
1999 Görlich D, Kutay U. Transport between the cell nucleus and the cytoplasm. Annual Review of Cell and Developmental Biology. 15: 607-60. PMID 10611974 DOI: 10.1146/Annurev.Cellbio.15.1.607  0.766
1999 Bayliss R, Ribbeck K, Akin D, Kent HM, Feldherr CM, Görlich D, Stewart M. Interaction between NTF2 and xFxFG-containing nucleoporins is required to mediate nuclear import of RanGDP. Journal of Molecular Biology. 293: 579-93. PMID 10543952 DOI: 10.1006/Jmbi.1999.3166  0.423
1999 Köhler M, Speck C, Christiansen M, Bischoff FR, Prehn S, Haller H, Görlich D, Hartmann E. Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import. Molecular and Cellular Biology. 19: 7782-91. PMID 10523667 DOI: 10.1128/Mcb.19.11.7782  0.371
1999 Jullien D, Görlich D, Laemmli UK, Adachi Y. Nuclear import of RPA in Xenopus egg extracts requires a novel protein XRIPalpha but not importin alpha. The Embo Journal. 18: 4348-58. PMID 10428972 DOI: 10.1093/Emboj/18.15.4348  0.459
1999 Vetter IR, Arndt A, Kutay U, Görlich D, Wittinghofer A. Structural view of the Ran-Importin beta interaction at 2.3 A resolution. Cell. 97: 635-46. PMID 10367892 DOI: 10.1016/S0092-8674(00)80774-6  0.776
1999 Jäkel S, Albig W, Kutay U, Bischoff FR, Schwamborn K, Doenecke D, Görlich D. The importin beta/importin 7 heterodimer is a functional nuclear import receptor for histone H1. The Embo Journal. 18: 2411-23. PMID 10228156 DOI: 10.1093/Emboj/18.9.2411  0.764
1999 Paraskeva E, Izaurralde E, Bischoff FR, Huber J, Kutay U, Hartmann E, Lührmann R, Görlich D. CRM1-mediated recycling of snurportin 1 to the cytoplasm. The Journal of Cell Biology. 145: 255-64. PMID 10209022 DOI: 10.1083/Jcb.145.2.255  0.786
1999 Lipowsky G, Bischoff FR, Izaurralde E, Kutay U, Schäfer S, Gross HJ, Beier H, Görlich D. Coordination of tRNA nuclear export with processing of tRNA. Rna (New York, N.Y.). 5: 539-49. PMID 10199570 DOI: 10.1017/S1355838299982134  0.697
1999 Ribbeck K, Kutay U, Paraskeva E, Görlich D. The translocation of transportin-cargo complexes through nuclear pores is independent of both Ran and energy. Current Biology : Cb. 9: 47-50. PMID 9889126 DOI: 10.1016/S0960-9822(99)80046-3  0.765
1998 Ribbeck K, Lipowsky G, Kent HM, Stewart M, Görlich D. NTF2 mediates nuclear import of Ran. The Embo Journal. 17: 6587-98. PMID 9822603 DOI: 10.1093/Emboj/17.22.6587  0.474
1998 Jäkel S, Görlich D. Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells. The Embo Journal. 17: 4491-502. PMID 9687515 DOI: 10.1093/emboj/17.15.4491  0.509
1998 Kutay U, Lipowsky G, Izaurralde E, Bischoff FR, Schwarzmaier P, Hartmann E, Görlich D. Identification of a tRNA-specific nuclear export receptor. Molecular Cell. 1: 359-69. PMID 9660920 DOI: 10.1016/S1097-2765(00)80036-2  0.762
1997 Bischoff FR, Görlich D. RanBP1 is crucial for the release of RanGTP from importin beta-related nuclear transport factors. Febs Letters. 419: 249-54. PMID 9428644 DOI: 10.1016/S0014-5793(97)01467-1  0.389
1997 Izaurralde E, Kutay U, von Kobbe C, Mattaj IW, Görlich D. The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus. The Embo Journal. 16: 6535-47. PMID 9351834 DOI: 10.1093/Emboj/16.21.6535  0.795
1997 Kutay U, Bischoff FR, Kostka S, Kraft R, Görlich D. Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor. Cell. 90: 1061-71. PMID 9323134 DOI: 10.1016/S0092-8674(00)80372-4  0.739
1997 Schlenstedt G, Smirnova E, Deane R, Solsbacher J, Kutay U, Görlich D, Ponstingl H, Bischoff FR. Yrb4p, a yeast ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus. The Embo Journal. 16: 6237-49. PMID 9321403 DOI: 10.1093/Emboj/16.20.6237  0.784
1997 Deane R, Schäfer W, Zimmermann HP, Mueller L, Görlich D, Prehn S, Ponstingl H, Bischoff FR. Ran-binding protein 5 (RanBP5) is related to the nuclear transport factor importin-beta but interacts differently with RanBP1. Molecular and Cellular Biology. 17: 5087-96. PMID 9271386  0.553
1997 Görlich D. Nuclear protein import. Current Opinion in Cell Biology. 9: 412-9. PMID 9159081 DOI: 10.1016/S0955-0674(97)80015-4  0.367
1997 Kutay U, Izaurralde E, Bischoff FR, Mattaj IW, Görlich D. Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex. The Embo Journal. 16: 1153-63. PMID 9135132 DOI: 10.1093/Emboj/16.6.1153  0.784
1996 Laskey RA, Görlich D, Madine MA, Makkerh JP, Romanowski P. Regulatory roles of the nuclear envelope. Experimental Cell Research. 229: 204-11. PMID 8986599 DOI: 10.1006/excr.1996.0361  0.648
1996 Görlich D, Panté N, Kutay U, Aebi U, Bischoff FR. Identification of different roles for RanGDP and RanGTP in nuclear protein import. The Embo Journal. 15: 5584-94. PMID 8896452 DOI: 10.1002/J.1460-2075.1996.Tb00943.X  0.798
1996 Görlich D, Kraft R, Kostka S, Vogel F, Hartmann E, Laskey RA, Mattaj IW, Izaurralde E. Importin provides a link between nuclear protein import and U snRNA export. Cell. 87: 21-32. PMID 8858145 DOI: 10.1016/S0092-8674(00)81319-7  0.684
1996 Lewis JD, Görlich D, Mattaj IW. A yeast cap binding protein complex (yCBC) acts at an early step in pre-mRNA splicing. Nucleic Acids Research. 24: 3332-6. PMID 8811086  0.302
1996 Görlich D, Henklein P, Laskey RA, Hartmann E. A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus. The Embo Journal. 15: 1810-7. PMID 8617226  0.687
1996 Görlich D, Mattaj IW. Nucleocytoplasmic transport. Science (New York, N.Y.). 271: 1513-8. PMID 8599106 DOI: 10.1126/science.271.5255.1513  0.338
1995 Hartmann E, Görlich D. A Ran-binding motif in nuclear pore proteins. Trends in Cell Biology. 5: 192-3. PMID 14731447 DOI: 10.1016/0962-8924(95)80004-Z  0.414
1995 Görlich D, Laskey RA. Roles of importin in nuclear protein import. Cold Spring Harbor Symposia On Quantitative Biology. 60: 695-9. PMID 8824444  0.618
1995 Oliver J, Jungnickel B, Görlich D, Rapoport T, High S. The Sec61 complex is essential for the insertion of proteins into the membrane of the endoplasmic reticulum. Febs Letters. 362: 126-30. PMID 7720858 DOI: 10.1016/0014-5793(95)00223-V  0.694
1995 Görlich D, Vogel F, Mills AD, Hartmann E, Laskey RA. Distinct functions for the two importin subunits in nuclear protein import. Nature. 377: 246-8. PMID 7675110 DOI: 10.1038/377246a0  0.699
1995 Görlich D, Kostka S, Kraft R, Dingwall C, Laskey RA, Hartmann E, Prehn S. Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope. Current Biology : Cb. 5: 383-92. PMID 7627554 DOI: 10.1016/S0960-9822(95)00079-0  0.678
1994 Kalies KU, Görlich D, Rapoport TA. Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex. The Journal of Cell Biology. 126: 925-34. PMID 8051212 DOI: 10.1083/Jcb.126.4.925  0.713
1994 Görlich D, Prehn S, Laskey RA, Hartmann E. Isolation of a protein that is essential for the first step of nuclear protein import. Cell. 79: 767-78. PMID 8001116 DOI: 10.1016/0092-8674(94)90067-1  0.642
1993 Görlich D, Rapoport TA. Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane. Cell. 75: 615-30. PMID 8242738 DOI: 10.1016/0092-8674(93)90483-7  0.686
1993 Hartmann E, Görlich D, Kostka S, Otto A, Kraft R, Knespel S, Bürger E, Rapoport TA, Prehn S. A tetrameric complex of membrane proteins in the endoplasmic reticulum. European Journal of Biochemistry / Febs. 214: 375-81. PMID 7916687 DOI: 10.1111/J.1432-1033.1993.Tb17933.X  0.702
1992 Görlich D, Prehn S, Hartmann E, Kalies KU, Rapoport TA. A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation. Cell. 71: 489-503. PMID 1423609 DOI: 10.1016/0092-8674(92)90517-G  0.678
1992 Rapoport TA, Görlich D, Müsch A, Hartmann E, Prehn S, Wiedmann M, Otto A, Kostka S, Kraft R. Components and mechanism of protein translocation across the ER membrane. Antonie Van Leeuwenhoek. 61: 119-22. PMID 1316096 DOI: 10.1007/Bf00580618  0.654
1992 Görlich D, Hartmann E, Prehn S, Rapoport TA. A protein of the endoplasmic reticulum involved early in polypeptide translocation. Nature. 357: 47-52. PMID 1315422 DOI: 10.1038/357047A0  0.675
1991 Görlich D, Kurzchalia TV, Wiedmann M, Rapoport TA. Probing the molecular environment of translocating polypeptide chains by cross-linking. Methods in Cell Biology. 34: 241-62. PMID 1943803 DOI: 10.1016/S0091-679X(08)61684-2  0.574
1990 Vogel F, Hartmann E, Görlich D, Rapoport TA. Segregation of the signal sequence receptor protein in the rough endoplasmic reticulum membrane. European Journal of Cell Biology. 53: 197-202. PMID 1964414  0.66
Show low-probability matches.