Marc R. Freeman, Ph.D. - Publications

Affiliations: 
Neurobiology University of Massachusetts Medical School, Worcester, MA, United States 
 Oregon Health and Science University, Portland, OR 
Area:
Glia neurobiology and neurodegeneration

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lin TH, Bis-Brewer DM, Sheehan AE, Townsend LN, Maddison DC, Züchner S, Smith GA, Freeman MR. TSG101 negatively regulates mitochondrial biogenesis in axons. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33972422 DOI: 10.1073/pnas.2018770118  0.44
2021 Ackerman SD, Perez-Catalan NA, Freeman MR, Doe CQ. Astrocytes close a motor circuit critical period. Nature. PMID 33828296 DOI: 10.1038/s41586-021-03441-2  1
2020 Hsu JM, Kang Y, Corty MM, Mathieson D, Peters OM, Freeman MR. Injury-Induced Inhibition of Bystander Neurons Requires dSarm and Signaling from Glia. Neuron. PMID 33296670 DOI: 10.1016/j.neuron.2020.11.012  0.64
2020 Ma Z, Freeman MR. TrpML-mediated astrocyte microdomain Ca transients regulate astrocyte-tracheal interactions. Elife. 9. PMID 33284108 DOI: 10.7554/eLife.58952  0.96
2019 Gu P, Gong J, Shang Y, Wang F, Ruppell KT, Ma Z, Sheehan AE, Freeman MR, Xiang Y. Polymodal Nociception in Drosophila Requires Alternative Splicing of TrpA1. Current Biology : Cb. PMID 31735672 DOI: 10.1016/J.Cub.2019.09.070  0.44
2019 Smith GA, Lin TH, Sheehan AE, Van der Goes van Naters W, Neukomm LJ, Graves HK, Bis-Brewer DM, Züchner S, Freeman MR. Glutathione S-Transferase Regulates Mitochondrial Populations in Axons through Increased Glutathione Oxidation. Neuron. PMID 31101394 DOI: 10.1016/J.Neuron.2019.04.017  0.48
2019 Freeman M. Decision letter: Astrocyte morphogenesis is dependent on BDNF signaling via astrocytic TrkB.T1 Elife. DOI: 10.7554/Elife.44667.018  0.92
2018 Cho S, Muthukumar AK, Stork T, Coutinho-Budd JC, Freeman MR. Focal adhesion molecules regulate astrocyte morphology and glutamate transporters to suppress seizure-like behavior. Proceedings of the National Academy of Sciences of the United States of America. PMID 30327343 DOI: 10.1073/Pnas.1800830115  0.36
2018 Peters OM, Lewis EA, Osterloh JM, Weiss A, Salameh JS, Metterville J, Brown RH, Freeman MR. Loss of Sarm1 does not suppress motor neuron degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis. Human Molecular Genetics. PMID 30010873 DOI: 10.1093/Hmg/Ddy260  0.44
2018 Farley JE, Burdett TC, Barria R, Neukomm LJ, Kenna KP, Landers JE, Freeman MR. Transcription factor Pebbled/RREB1 regulates injury-induced axon degeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 29295933 DOI: 10.1073/Pnas.1715837115  0.44
2017 Coutinho-Budd JC, Sheehan AE, Freeman MR. The secreted neurotrophin Spätzle 3 promotes glial morphogenesis and supports neuronal survival and function. Genes & Development. PMID 29138279 DOI: 10.1101/Gad.305888.117  0.64
2017 Neukomm LJ, Burdett TC, Seeds AM, Hampel S, Coutinho-Budd JC, Farley JE, Wong J, Karadeniz YB, Osterloh JM, Sheehan AE, Freeman MR. Axon Death Pathways Converge on Axundead to Promote Functional and Structural Axon Disassembly. Neuron. 95: 78-91.e5. PMID 28683272 DOI: 10.1016/J.Neuron.2017.06.031  0.44
2017 Lu TY, MacDonald JM, Neukomm LJ, Sheehan AE, Bradshaw R, Logan MA, Freeman MR. Axon degeneration induces glial responses through Draper-TRAF4-JNK signalling. Nature Communications. 8: 14355. PMID 28165006 DOI: 10.1038/Ncomms14355  0.96
2016 Ma Z, Stork T, Bergles DE, Freeman MR. Neuromodulators signal through astrocytes to alter neural circuit activity and behaviour. Nature. PMID 27828941 DOI: 10.1038/Nature20145  0.4
2016 He J, Zhou R, Wu Z, Carrasco MA, Kurshan PT, Farley JE, Simon DJ, Wang G, Han B, Hao J, Heller E, Freeman MR, Shen K, Maniatis T, Tessier-Lavigne M, et al. Prevalent presence of periodic actin-spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species. Proceedings of the National Academy of Sciences of the United States of America. PMID 27162329 DOI: 10.1073/Pnas.1605707113  1
2016 Francis MM, Freeman MR. Dendrites actively restrain axon outgrowth and regeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 27147603 DOI: 10.1073/Pnas.1605215113  1
2016 Henninger N, Bouley J, Sikoglu EM, An J, Moore CM, King JA, Bowser R, Freeman MR, Brown RH. Attenuated traumatic axonal injury and improved functional outcome after traumatic brain injury in mice lacking Sarm1. Brain : a Journal of Neurology. PMID 26912636 DOI: 10.1093/Brain/Aww001  1
2015 Farley JE, Freeman MR. Letting Go of JuNK by Disassembly of Adhesive Complexes. Neuron. 88: 848-50. PMID 26637791 DOI: 10.1016/J.Neuron.2015.11.015  1
2015 Gururajan M, Cavassani KA, Sievert M, Duan P, Lichterman J, Huang JM, Smith B, You S, Nandana S, Chu GC, Mink S, Josson S, Liu C, Morello M, Jones LW, ... ... Freeman MR, et al. SRC family kinase FYN promotes the neuroendocrine phenotype and visceral metastasis in advanced prostate cancer. Oncotarget. PMID 26624980 DOI: 10.18632/Oncotarget.6398  0.68
2015 Jeong P, Ha YS, Yun SJ, Yoon HY, Freeman MR, Kim J, Kim WJ. Assess the expression of ubiquitin specific protease USP2a for bladder cancer diagnosis. Bmc Urology. 15: 80. PMID 26250800 DOI: 10.1186/s12894-015-0074-x  0.84
2015 Sreedharan J, Neukomm LJ, Brown RH, Freeman MR. Age-Dependent TDP-43-Mediated Motor Neuron Degeneration Requires GSK3, hat-trick, and xmas-2. Current Biology : Cb. PMID 26234214 DOI: 10.1016/J.Cub.2015.06.045  1
2015 Morley S, You S, Pollan S, Choi J, Zhou B, Hager MH, Steadman K, Spinelli C, Rajendran K, Gertych A, Kim J, Adam RM, Yang W, Krishnan R, Knudsen BS, ... ... Freeman MR, et al. Regulation of microtubule dynamics by DIAPH3 influences amoeboid tumor cell mechanics and sensitivity to taxanes. Scientific Reports. 5: 12136. PMID 26179371 DOI: 10.1038/srep12136  0.32
2015 Freeman MR. Drosophila Central Nervous System Glia. Cold Spring Harbor Perspectives in Biology. PMID 25722465 DOI: 10.1101/Cshperspect.A020552  1
2015 Wen H, Lee T, You S, Park SH, Song H, Eilber KS, Anger JT, Freeman MR, Park S, Kim J. Urinary metabolite profiling combined with computational analysis predicts interstitial cystitis-associated candidate biomarkers. Journal of Proteome Research. 14: 541-8. PMID 25353990 DOI: 10.1021/pr5007729  0.84
2015 Jeong P, Ha YS, Yun SJ, Yoon HY, Freeman MR, Kim J, Kim WJ. Assess the expression of ubiquitin specific protease USP2a for bladder cancer diagnosis Bmc Urology. 15. DOI: 10.1186/s12894-015-0074-x  0.32
2014 Doherty J, Sheehan AE, Bradshaw R, Fox AN, Lu TY, Freeman MR. PI3K signaling and Stat92E converge to modulate glial responsiveness to axonal injury. Plos Biology. 12: e1001985. PMID 25369313 DOI: 10.1371/Journal.Pbio.1001985  1
2014 Muthukumar AK, Stork T, Freeman MR. Activity-dependent regulation of astrocyte GAT levels during synaptogenesis. Nature Neuroscience. 17: 1340-50. PMID 25151265 DOI: 10.1038/Nn.3791  1
2014 Lu TY, Doherty J, Freeman MR. DRK/DOS/SOS converge with Crk/Mbc/dCed-12 to activate Rac1 during glial engulfment of axonal debris. Proceedings of the National Academy of Sciences of the United States of America. 111: 12544-9. PMID 25099352 DOI: 10.1073/Pnas.1403450111  1
2014 Yang W, Ramachandran A, You S, Jeong H, Morley S, Mulone MD, Logvinenko T, Kim J, Hwang D, Freeman MR, Adam RM. Integration of proteomic and transcriptomic profiles identifies a novel PDGF-MYC network in human smooth muscle cells. Cell Communication and Signaling : Ccs. 12: 44. PMID 25080971 DOI: 10.1186/s12964-014-0044-z  0.32
2014 Burdett TC, Freeman MR. Neuroscience. Astrocytes eyeball axonal mitochondria. Science (New York, N.Y.). 345: 385-6. PMID 25061193 DOI: 10.1126/Science.1258295  1
2014 Stork T, Sheehan A, Tasdemir-Yilmaz OE, Freeman MR. Neuron-glia interactions through the Heartless FGF receptor signaling pathway mediate morphogenesis of Drosophila astrocytes. Neuron. 83: 388-403. PMID 25033182 DOI: 10.1016/J.Neuron.2014.06.026  1
2014 Neukomm LJ, Burdett TC, Gonzalez MA, Züchner S, Freeman MR. Rapid in vivo forward genetic approach for identifying axon death genes in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 111: 9965-70. PMID 24958874 DOI: 10.1073/Pnas.1406230111  1
2014 Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment. Proteomics. 14: 1845-56. PMID 24946052 DOI: 10.1002/pmic.201400008  0.32
2014 Freeman MR. Signaling mechanisms regulating Wallerian degeneration. Current Opinion in Neurobiology. 27: 224-31. PMID 24907513 DOI: 10.1016/J.Conb.2014.05.001  1
2014 Neukomm LJ, Freeman MR. Diverse cellular and molecular modes of axon degeneration. Trends in Cell Biology. 24: 515-23. PMID 24780172 DOI: 10.1016/J.Tcb.2014.04.003  1
2014 Rooney TM, Freeman MR. Drosophila models of neuronal injury. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 54: 291-5. PMID 24615442 DOI: 10.1093/Ilar/Ilt057  1
2014 Morley S, Hager MH, Pollan SG, Knudsen B, Di Vizio D, Freeman MR. Trading in your spindles for blebs: the amoeboid tumor cell phenotype in prostate cancer. Asian Journal of Andrology. 16: 530-5. PMID 24589458 DOI: 10.4103/1008-682X.122877  0.32
2014 Kerr KS, Fuentes-Medel Y, Brewer C, Barria R, Ashley J, Abruzzi KC, Sheehan A, Tasdemir-Yilmaz OE, Freeman MR, Budnik V. Glial wingless/Wnt regulates glutamate receptor clustering and synaptic physiology at the Drosophila neuromuscular junction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2910-20. PMID 24553932 DOI: 10.1523/Jneurosci.3714-13.2014  1
2014 Chu GC, Zhau HE, Wang R, Rogatko A, Feng X, Zayzafoon M, Liu Y, Farach-Carson MC, You S, Kim J, Freeman MR, Chung LW. RANK- and c-Met-mediated signal network promotes prostate cancer metastatic colonization. Endocrine-Related Cancer. 21: 311-26. PMID 24478054 DOI: 10.1530/Erc-13-0548  0.68
2014 Kim J, Morley S, Le M, Bedoret D, Umetsu DT, Di Vizio D, Freeman MR. Enhanced shedding of extracellular vesicles from amoeboid prostate cancer cells: potential effects on the tumor microenvironment. Cancer Biology & Therapy. 15: 409-18. PMID 24423651 DOI: 10.4161/cbt.27627  0.32
2014 Tasdemir-Yilmaz OE, Freeman MR. Astrocytes engage unique molecular programs to engulf pruned neuronal debris from distinct subsets of neurons. Genes & Development. 28: 20-33. PMID 24361692 DOI: 10.1101/Gad.229518.113  1
2014 Mukhopadhyay NK, Kim J, You S, Morello M, Hager MH, Huang WC, Ramachandran A, Yang J, Cinar B, Rubin MA, Adam RM, Oesterreich S, Di Vizio D, Freeman MR. Scaffold attachment factor B1 regulates the androgen receptor in concert with the growth inhibitory kinase MST1 and the methyltransferase EZH2. Oncogene. 33: 3235-45. PMID 23893242 DOI: 10.1038/Onc.2013.294  0.32
2013 Corty MM, Freeman MR. Cell biology in neuroscience: Architects in neural circuit design: glia control neuron numbers and connectivity. The Journal of Cell Biology. 203: 395-405. PMID 24217617 DOI: 10.1083/Jcb.201306099  1
2013 Freeman MR, Rowitch DH. Evolving concepts of gliogenesis: a look way back and ahead to the next 25 years. Neuron. 80: 613-23. PMID 24183014 DOI: 10.1016/J.Neuron.2013.10.034  1
2013 Milde S, Fox AN, Freeman MR, Coleman MP. Deletions within its subcellular targeting domain enhance the axon protective capacity of Nmnat2 in vivo. Scientific Reports. 3: 2567. PMID 23995269 DOI: 10.1038/Srep02567  1
2013 Li X, Chen YT, Josson S, Mukhopadhyay NK, Kim J, Freeman MR, Huang WC. MicroRNA-185 and 342 inhibit tumorigenicity and induce apoptosis through blockade of the SREBP metabolic pathway in prostate cancer cells. Plos One. 8: e70987. PMID 23951060 DOI: 10.1371/Journal.Pone.0070987  0.32
2013 Coutinho-Budd J, Freeman MR. Probing the enigma: unraveling glial cell biology in invertebrates. Current Opinion in Neurobiology. 23: 1073-9. PMID 23896311 DOI: 10.1016/J.Conb.2013.07.002  1
2013 Ayala G, Morello M, Frolov A, You S, Li R, Rosati F, Bartolucci G, Danza G, Adam RM, Thompson TC, Lisanti MP, Freeman MR, Di Vizio D. Loss of caveolin-1 in prostate cancer stroma correlates with reduced relapse-free survival and is functionally relevant to tumour progression. The Journal of Pathology. 231: 77-87. PMID 23729330 DOI: 10.1002/Path.4217  0.32
2013 Freeman MR. The ubiquitin ligase Siah2 is revealed as an accomplice of the androgen receptor in castration resistant prostate cancer. Asian Journal of Andrology. 15: 447-8. PMID 23708461 DOI: 10.1038/aja.2013.62  0.32
2013 Macdonald JM, Doherty J, Hackett R, Freeman MR. The c-Jun kinase signaling cascade promotes glial engulfment activity through activation of draper and phagocytic function. Cell Death and Differentiation. 20: 1140-8. PMID 23618811 DOI: 10.1038/Cdd.2013.30  1
2013 Solomon KR, Allott EH, Freeman MR, Freedland SJ. Words of wisdom. Re: Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1. European Urology. 63: 1128-9. PMID 23608078 DOI: 10.1016/j.eururo.2013.03.017  0.32
2013 Park JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS, Kim KP. Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. Proteomics. 13: 2125-34. PMID 23585444 DOI: 10.1002/pmic.201200323  0.32
2013 Franz MC, Anderle P, Bürzle M, Suzuki Y, Freeman MR, Hediger MA, Kovacs G. Zinc transporters in prostate cancer. Molecular Aspects of Medicine. 34: 735-41. PMID 23506906 DOI: 10.1016/j.mam.2012.11.007  0.32
2013 Liu Z, Zanata SM, Kim J, Peterson MA, Di Vizio D, Chirieac LR, Pyne S, Agostini M, Freeman MR, Loda M. The ubiquitin-specific protease USP2a prevents endocytosis-mediated EGFR degradation. Oncogene. 32: 1660-9. PMID 22710717 DOI: 10.1038/onc.2012.188  0.32
2013 Freeman MR, Solomon KR. Statin drugs and prostate cancer: Time to consider proactive strategies in patients Journal of Urology. 189: 1192-1193. DOI: 10.1016/j.juro.2013.01.033  0.32
2013 Stork T, Freeman MR. Invertebrate Glia Comprehensive Developmental Neuroscience: Patterning and Cell Type Specification in the Developing Cns and Pns. 891-910. DOI: 10.1016/B978-0-12-397265-1.00090-3  1
2012 Gonzalez MA, Van Booven D, Hulme W, Ulloa RH, Lebrigio RF, Osterloh J, Logan M, Freeman M, Zuchner S. Whole Genome Sequencing and a New Bioinformatics Platform Allow for Rapid Gene Identification in D. melanogaster EMS Screens. Biology. 1: 766-77. PMID 24832518 DOI: 10.3390/Biology1030766  1
2012 You S, Yang W, Anger JT, Freeman MR, Kim J. 'Omics' approaches to understanding interstitial cystitis/painful bladder syndrome/bladder pain syndrome. International Neurourology Journal. 16: 159-68. PMID 23346481 DOI: 10.5213/inj.2012.16.4.159  0.32
2012 Kim J, Keay SK, You S, Loda M, Freeman MR. A synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2. Plos One. 7: e50392. PMID 23236372 DOI: 10.1371/journal.pone.0050392  0.32
2012 Di Vizio D, Morello M, Dudley AC, Schow PW, Adam RM, Morley S, Mulholland D, Rotinen M, Hager MH, Insabato L, Moses MA, Demichelis F, Lisanti MP, Wu H, Klagsbrun M, ... ... Freeman MR, et al. Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease. The American Journal of Pathology. 181: 1573-84. PMID 23022210 DOI: 10.1016/J.Ajpath.2012.07.030  0.32
2012 Fuentes-Medel Y, Ashley J, Barria R, Maloney R, Freeman M, Budnik V. Integration of a retrograde signal during synapse formation by glia-secreted TGF-β ligand. Current Biology : Cb. 22: 1831-8. PMID 22959350 DOI: 10.1016/J.Cub.2012.07.063  1
2012 Wishart TM, Rooney TM, Lamont DJ, Wright AK, Morton AJ, Jackson M, Freeman MR, Gillingwater TH. Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo. Plos Genetics. 8: e1002936. PMID 22952455 DOI: 10.1371/Journal.Pgen.1002936  1
2012 Pelton K, Freeman MR, Solomon KR. Cholesterol and prostate cancer. Current Opinion in Pharmacology. 12: 751-9. PMID 22824430 DOI: 10.1016/j.coph.2012.07.006  0.32
2012 Pelton K, Krieder J, Joiner D, Freeman MR, Goldstein SA, Solomon KR. Hypercholesterolemia promotes an osteoporotic phenotype. The American Journal of Pathology. 181: 928-36. PMID 22770664 DOI: 10.1016/J.Ajpath.2012.05.034  0.32
2012 Kim J, Di Vizio D, Kim TK, Kim J, Kim M, Pelton K, Clinton SK, Hai T, Hwang D, Solomon KR, Freeman MR. The response of the prostate to circulating cholesterol: activating transcription factor 3 (ATF3) as a prominent node in a cholesterol-sensing network. Plos One. 7: e39448. PMID 22768301 DOI: 10.1371/Journal.Pone.0039448  0.32
2012 Yang W, Kim Y, Kim TK, Keay SK, Kim KP, Steen H, Freeman MR, Hwang D, Kim J. Integration analysis of quantitative proteomics and transcriptomics data identifies potential targets of frizzled-8 protein-related antiproliferative factor in vivo. Bju International. 110: E1138-46. PMID 22738385 DOI: 10.1111/J.1464-410X.2012.11299.X  0.32
2012 Ziegenfuss JS, Doherty J, Freeman MR. Distinct molecular pathways mediate glial activation and engulfment of axonal debris after axotomy. Nature Neuroscience. 15: 979-87. PMID 22706267 DOI: 10.1038/Nn.3135  1
2012 Osterloh JM, Yang J, Rooney TM, Fox AN, Adalbert R, Powell EH, Sheehan AE, Avery MA, Hackett R, Logan MA, MacDonald JM, Ziegenfuss JS, Milde S, Hou YJ, Nathan C, ... ... Freeman MR, et al. dSarm/Sarm1 is required for activation of an injury-induced axon death pathway. Science (New York, N.Y.). 337: 481-4. PMID 22678360 DOI: 10.1126/Science.1223899  1
2012 Hager MH, Morley S, Bielenberg DR, Gao S, Morello M, Holcomb IN, Liu W, Mouneimne G, Demichelis F, Kim J, Solomon KR, Adam RM, Isaacs WB, Higgs HN, Vessella RL, ... ... Freeman MR, et al. DIAPH3 governs the cellular transition to the amoeboid tumour phenotype. Embo Molecular Medicine. 4: 743-60. PMID 22593025 DOI: 10.1002/Emmm.201200242  0.32
2012 Logan MA, Hackett R, Doherty J, Sheehan A, Speese SD, Freeman MR. Negative regulation of glial engulfment activity by Draper terminates glial responses to axon injury. Nature Neuroscience. 15: 722-30. PMID 22426252 DOI: 10.1038/Nn.3066  1
2012 Avery MA, Rooney TM, Pandya JD, Wishart TM, Gillingwater TH, Geddes JW, Sullivan PG, Freeman MR. WldS prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca2+ buffering. Current Biology : Cb. 22: 596-600. PMID 22425157 DOI: 10.1016/J.Cub.2012.02.043  1
2012 Freeman MR, Yang W, Di Vizio D. Caveolin-1 and prostate cancer progression. Advances in Experimental Medicine and Biology. 729: 95-110. PMID 22411316 DOI: 10.1007/978-1-4614-1222-9_7  0.32
2012 Kim J, Kim WJ, Liu Z, Loda M, Freeman MR. The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer. Cell Cycle (Georgetown, Tex.). 11: 1123-30. PMID 22370483 DOI: 10.4161/cc.11.6.19550  0.32
2012 Mostaghel EA, Solomon KR, Pelton K, Freeman MR, Montgomery RB. Impact of circulating cholesterol levels on growth and intratumoral androgen concentration of prostate tumors. Plos One. 7: e30062. PMID 22279565 DOI: 10.1371/journal.pone.0030062  0.32
2012 Stork T, Bernardos R, Freeman MR. Analysis of glial cell development and function in Drosophila. Cold Spring Harbor Protocols. 2012: 1-17. PMID 22194269 DOI: 10.1101/Pdb.Top067587  1
2011 Kim J, Freeman MR. Antiproliferative factor signaling and interstitial cystitis/painful bladder syndrome. International Neurourology Journal. 15: 184-91. PMID 22259731 DOI: 10.5213/inj.2011.15.4.184  0.32
2011 Freeman MR, Kim J, Lisanti MP, Di Vizio D. A metabolic perturbation by U0126 identifies a role for glutamine in resveratrol-induced cell death. Cancer Biology & Therapy. 12: 966-77. PMID 22108021 DOI: 10.4161/Cbt.12.11.18136  0.32
2011 Freeman MR, Solomon KR. Cholesterol and benign prostate disease. Differentiation; Research in Biological Diversity. 82: 244-52. PMID 21862201 DOI: 10.1016/j.diff.2011.04.005  0.32
2011 Dowal L, Yang W, Freeman MR, Steen H, Flaumenhaft R. Proteomic analysis of palmitoylated platelet proteins. Blood. 118: e62-73. PMID 21813449 DOI: 10.1182/Blood-2011-05-353078  0.32
2011 Solomon KR, Freeman MR. The complex interplay between cholesterol and prostate malignancy. The Urologic Clinics of North America. 38: 243-59. PMID 21798387 DOI: 10.1016/j.ucl.2011.04.001  0.32
2011 Featherstone D, Freeman M. Introduction Glia. 59: 1213-1214. PMID 21732422 DOI: 10.1002/Glia.21197  1
2011 Cinar B, Collak FK, Lopez D, Akgul S, Mukhopadhyay NK, Kilicarslan M, Gioeli DG, Freeman MR. MST1 is a multifunctional caspase-independent inhibitor of androgenic signaling. Cancer Research. 71: 4303-13. PMID 21512132 DOI: 10.1158/0008-5472.Can-10-4532  0.32
2011 Yang W, Chung YG, Kim Y, Kim TK, Keay SK, Zhang CO, Ji M, Hwang D, Kim KP, Steen H, Freeman MR, Kim J. Quantitative proteomics identifies a beta-catenin network as an element of the signaling response to Frizzled-8 protein-related antiproliferative factor. Molecular & Cellular Proteomics : McP. 10: M110.007492. PMID 21422242 DOI: 10.1074/Mcp.M110.007492  0.32
2011 Wu X, Gao H, Ke W, Hager M, Xiao S, Freeman MR, Zhu Z. VentX trans-activates p53 and p16ink4a to regulate cellular senescence. The Journal of Biological Chemistry. 286: 12693-701. PMID 21325273 DOI: 10.1074/jbc.M110.206078  0.32
2011 Kim J, Ji M, DiDonato JA, Rackley RR, Kuang M, Sadhukhan PC, Mauney JR, Keay SK, Freeman MR, Liou LS, Adam RM. An hTERT-immortalized human urothelial cell line that responds to anti-proliferative factor. In Vitro Cellular & Developmental Biology. Animal. 47: 2-9. PMID 21136194 DOI: 10.1007/S11626-010-9350-Y  0.32
2010 Freeman MR. Specification and morphogenesis of astrocytes. Science (New York, N.Y.). 330: 774-8. PMID 21051628 DOI: 10.1126/Science.1190928  1
2010 Pelton K, Di Vizio D, Insabato L, Schaffner CP, Freeman MR, Solomon KR. Ezetimibe reduces enlarged prostate in an animal model of benign prostatic hyperplasia. The Journal of Urology. 184: 1555-9. PMID 20728125 DOI: 10.1016/j.juro.2010.05.083  0.32
2010 McPhee CK, Logan MA, Freeman MR, Baehrecke EH. Activation of autophagy during cell death requires the engulfment receptor Draper. Nature. 465: 1093-6. PMID 20577216 DOI: 10.1038/Nature09127  1
2010 Peleg S, Sellin JH, Wang Y, Freeman MR, Umar S. Suppression of aberrant transient receptor potential cation channel, subfamily V, member 6 expression in hyperproliferative colonic crypts by dietary calcium. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G593-601. PMID 20508153 DOI: 10.1152/ajpgi.00193.2010  0.32
2010 Freeman MR, Di Vizio D, Solomon KR. The Rafts of the Medusa: cholesterol targeting in cancer therapy. Oncogene. 29: 3745-7. PMID 20440260 DOI: 10.1038/onc.2010.132  0.32
2010 Yang W, Cai Q, Lui VW, Everley PA, Kim J, Bhola N, Quesnelle KM, Zetter BR, Steen H, Freeman MR, Grandis JR. Quantitative proteomics analysis reveals molecular networks regulated by epidermal growth factor receptor level in head and neck cancer. Journal of Proteome Research. 9: 3073-82. PMID 20426488 DOI: 10.1021/Pr901211J  0.32
2010 Coleman MP, Freeman MR. Wallerian degeneration, wld(s), and nmnat. Annual Review of Neuroscience. 33: 245-67. PMID 20345246 DOI: 10.1146/Annurev-Neuro-060909-153248  1
2010 Yang W, Di Vizio D, Kirchner M, Steen H, Freeman MR. Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes. Molecular & Cellular Proteomics : McP. 9: 54-70. PMID 19801377 DOI: 10.1074/Mcp.M800448-Mcp200  0.32
2009 Osterloh JM, Freeman MR. Neuronal death or dismemberment mediated by Sox14. Nature Neuroscience. 12: 1479-80. PMID 19935724 DOI: 10.1038/Nn1209-1479  1
2009 Fuentes-Medel Y, Logan MA, Ashley J, Ataman B, Budnik V, Freeman MR. Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris. Plos Biology. 7: e1000184. PMID 19707574 DOI: 10.1371/Journal.Pbio.1000184  1
2009 Freeman M. Marc Freeman: fishing for the function of fly glia. Interview by Ruth Williams. The Journal of Cell Biology. 186: 302-3. PMID 19667123 DOI: 10.1083/jcb.1863pi  0.36
2009 Vaezzadeh AR, Steen H, Freeman MR, Lee RS. Proteomics and opportunities for clinical translation in urological disease. The Journal of Urology. 182: 835-43. PMID 19616261 DOI: 10.1016/J.Juro.2009.05.001  0.32
2009 Di Vizio D, Morello M, Sotgia F, Pestell RG, Freeman MR, Lisanti MP. An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation. Cell Cycle (Georgetown, Tex.). 8: 2420-4. PMID 19556867 DOI: 10.4161/Cc.8.15.9116  0.32
2009 Di Vizio D, Kim J, Hager MH, Morello M, Yang W, Lafargue CJ, True LD, Rubin MA, Adam RM, Beroukhim R, Demichelis F, Freeman MR. Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease. Cancer Research. 69: 5601-9. PMID 19549916 DOI: 10.1158/0008-5472.Can-08-3860  0.32
2009 Kim J, Yanagihara Y, Kikugawa T, Ji M, Tanji N, Masayoshi Y, Freeman MR. A signaling network in phenylephrine-induced benign prostatic hyperplasia. Endocrinology. 150: 3576-83. PMID 19443575 DOI: 10.1210/en.2008-1782  0.32
2009 Doherty J, Logan MA, Ta?demir OE, Freeman MR. Ensheathing glia function as phagocytes in the adult Drosophila brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4768-81. PMID 19369546 DOI: 10.1523/Jneurosci.5951-08.2009  1
2009 Mukhopadhyay NK, Kim J, Cinar B, Ramachandran A, Hager MH, Di Vizio D, Adam RM, Rubin MA, Raychaudhuri P, De Benedetti A, Freeman MR. Heterogeneous nuclear ribonucleoprotein K is a novel regulator of androgen receptor translation. Cancer Research. 69: 2210-8. PMID 19258514 DOI: 10.1158/0008-5472.Can-08-2308  0.32
2009 Avery MA, Sheehan AE, Kerr KS, Wang J, Freeman MR. Wld S requires Nmnat1 enzymatic activity and N16-VCP interactions to suppress Wallerian degeneration. The Journal of Cell Biology. 184: 501-13. PMID 19237597 DOI: 10.1083/Jcb.200808042  1
2009 Qi M, Liu Y, Freeman MR, Solomon KR. Cholesterol-regulated stress fiber formation. Journal of Cellular Biochemistry. 106: 1031-40. PMID 19229870 DOI: 10.1002/jcb.22081  0.32
2009 Solomon KR, Pelton K, Boucher K, Joo J, Tully C, Zurakowski D, Schaffner CP, Kim J, Freeman MR. Ezetimibe is an inhibitor of tumor angiogenesis. The American Journal of Pathology. 174: 1017-26. PMID 19179610 DOI: 10.2353/ajpath.2009.080551  0.32
2009 Kim J, Keay SK, Freeman MR. Heparin-binding epidermal growth factor-like growth factor functionally antagonizes interstitial cystitis antiproliferative factor via mitogen-activated protein kinase pathway activation Bju International. 103: 541-546. PMID 18990151 DOI: 10.1111/j.1464-410X.2008.08097.x  0.32
2008 Ziegenfuss JS, Biswas R, Avery MA, Hong K, Sheehan AE, Yeung YG, Stanley ER, Freeman MR. Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling. Nature. 453: 935-9. PMID 18432193 DOI: 10.1038/Nature06901  1
2007 Freeman MR. A look inside. Neuron Glia Biology. 3: 1-3. PMID 18634573 DOI: 10.1017/S1740925X07000646  1
2007 Logan MA, Freeman MR. The scoop on the fly brain: glial engulfment functions in Drosophila. Neuron Glia Biology. 3: 63-74. PMID 18172512 DOI: 10.1017/S1740925X07000646  1
2007 Emery P, Freeman MR. Glia got rhythm. Neuron. 55: 337-9. PMID 17678846 DOI: 10.1016/J.Neuron.2007.07.014  1
2006 MacDonald JM, Beach MG, Porpiglia E, Sheehan AE, Watts RJ, Freeman MR. The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons. Neuron. 50: 869-81. PMID 16772169 DOI: 10.1016/J.Neuron.2006.04.028  1
2006 Freeman MR. Sculpting the nervous system: glial control of neuronal development. Current Opinion in Neurobiology. 16: 119-25. PMID 16387489 DOI: 10.1016/J.Conb.2005.12.004  1
2006 Freeman MR, Doherty J. Glial cell biology in Drosophila and vertebrates. Trends in Neurosciences. 29: 82-90. PMID 16377000 DOI: 10.1016/J.Tins.2005.12.002  1
2005 Freeman MR. Glial (and neuronal) cells missing. Neuron. 48: 163-5. PMID 16242394 DOI: 10.1016/J.Neuron.2005.10.002  1
2005 Freeman MR. Glial control of synaptogenesis. Cell. 120: 292-3. PMID 15707887 DOI: 10.1016/J.Cell.2005.01.021  1
2003 Freeman MR, Delrow J, Kim J, Johnson E, Doe CQ. Unwrapping glial biology: Gcm target genes regulating glial development, diversification, and function. Neuron. 38: 567-80. PMID 12765609 DOI: 10.1016/S0896-6273(03)00289-7  1
2001 Freeman MR, Doe CQ. Moving muscle. Jeb signaling in Drosophila. Developmental Cell. 1: 587-8. PMID 11709176 DOI: 10.1016/S1534-5807(01)00080-6  1
2001 Freeman MR, Doe CQ. Asymmetric Prospero localization is required to generate mixed neuronal/glial lineages in the Drosophila CNS. Development (Cambridge, England). 128: 4103-12. PMID 11641232  1
1999 Freeman MR, Dobritsa A, Gaines P, Segraves WA, Carlson JR. The dare gene: steroid hormone production, olfactory behavior, and neural degeneration in Drosophila. Development (Cambridge, England). 126: 4591-602. PMID 10498693  1
1999 Buszczak M, Freeman MR, Carlson JR, Bender M, Cooley L, Segraves WA. Ecdysone response genes govern egg chamber development during mid-oogenesis in Drosophila. Development (Cambridge, England). 126: 4581-9. PMID 10498692  1
1999 Clyne PJ, Warr CG, Freeman MR, Lessing D, Kim J, Carlson JR. A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila. Neuron. 22: 327-38. PMID 10069338 DOI: 10.1016/S0896-6273(00)81093-4  1
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