John P. Svaren - Publications

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
Molecular Biology, Neuroscience Biology

102 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Veneri FA, Prada V, Mastrangelo R, Ferri C, Nobbio L, Passalacqua M, Milanesi M, Bianchi F, Del Carro U, Vallat JM, Duong P, Svaren J, Schenone A, Grandis M, D'Antonio M. A novel mouse model of CMT1B identifies hyperglycosylation as a new pathogenetic mechanism. Human Molecular Genetics. PMID 35908287 DOI: 10.1093/hmg/ddac170  0.33
2022 Ramesh R, Manurung Y, Ma KH, Blakely T, Won S, Ramos OM, Wyatt E, Awatramani R, Svaren J. JUN Regulation of Injury-induced Enhancers in Schwann Cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35906072 DOI: 10.1523/JNEUROSCI.2533-21.2022  0.327
2022 Park HJ, Tsai E, Huang D, Weaver M, Frick L, Alcantara A, Moran JJ, Patzig J, Melendez-Vasquez CV, Crabtree GR, Feltri ML, Svaren J, Casaccia P. ACTL6a coordinates axonal caliber recognition and myelination in the peripheral nerve. Iscience. 25: 104132. PMID 35434551 DOI: 10.1016/j.isci.2022.104132  0.424
2021 Martinez NJ, Braisted JC, Dranchak PK, Moran JJ, Larson H, Queme B, Pak E, Dutra A, Rai G, Cheng KC, Svaren J, Inglese J. Genome-Edited Coincidence and PMP22-HiBiT Fusion Reporter Cell Lines Enable an Artifact-Suppressive Quantitative High-Throughput Screening Strategy for Gene-Dosage Disorder Drug Discovery. Acs Pharmacology & Translational Science. 4: 1422-1436. PMID 34423274 DOI: 10.1021/acsptsci.1c00110  0.422
2021 Duong P, Ma KH, Ramesh R, Moran JJ, Won S, Svaren J. H3K27 demethylases are dispensable for activation of Polycomb-regulated injury response genes in peripheral nerve. The Journal of Biological Chemistry. 100852. PMID 34090875 DOI: 10.1016/j.jbc.2021.100852  0.347
2021 Wagstaff LJ, Gomez-Sanchez JA, Fazal SV, Otto GW, Kilpatrick AM, Michael K, Wong LY, Ma KH, Turmaine M, Svaren J, Gordon T, Arthur-Farraj P, Velasco-Aviles S, Cabedo H, Benito C, et al. Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun. Elife. 10. PMID 33475496 DOI: 10.7554/eLife.62232  0.352
2020 Lupo V, Won S, Frasquet M, Schnitzler MS, Komath SS, Pascual-Pascual SI, Espinós C, Svaren J, Sevilla T. Bi-allelic mutations in EGR2 cause autosomal recessive demyelinating neuropathy by disrupting the EGR2-NAB complex. European Journal of Neurology. PMID 32896048 DOI: 10.1111/Ene.14512  0.388
2020 Damaschke NA, Gawdzik J, Avilla M, Yang B, Svaren J, Roopra A, Luo JH, Yu YP, Keles S, Jarrard DF. CTCF loss mediates unique DNA hypermethylation landscapes in human cancers. Clinical Epigenetics. 12: 80. PMID 32503656 DOI: 10.1186/S13148-020-00869-7  0.343
2020 Pantera H, Hu B, Moiseev D, Dunham C, Rashid J, Moran JJ, Krentz K, Rubinstein CD, Won S, Li J, Svaren J. Pmp22 Super-enhancer Deletion Causes Tomacula Formation and Conduction Block in Peripheral Nerves. Human Molecular Genetics. PMID 32356557 DOI: 10.1093/Hmg/Ddaa082  0.605
2020 Pantera H, Shy ME, Svaren J. Regulating PMP22 expression as a dosage sensitive neuropathy gene. Brain Research. 1726: 146491. PMID 31586623 DOI: 10.1016/J.Brainres.2019.146491  0.518
2019 Wang H, Davison M, Wang K, Xia TH, Kramer M, Call K, Luo J, Wu X, Zuccarino R, Bacon C, Bai Y, Moran JJ, Gutmann L, Feely SME, Grider T, ... ... Svaren J, et al. Transmembrane protease serine 5: a novel Schwann cell plasma marker for CMT1A. Annals of Clinical and Translational Neurology. PMID 31833243 DOI: 10.1002/Acn3.50965  0.31
2019 Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Schwab MH, Nave K, et al. Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy. Human Molecular Genetics. 28: 2282. PMID 31220267 DOI: 10.1093/hmg/ddz037  0.351
2019 Tao F, Beecham GW, Rebelo AP, Blanton SH, Moran JJ, Lopez-Anido C, Svaren J, Abreu L, Rizzo D, Kirk CA, Wu X, Feely S, Verhamme C, Saporta MA, Herrmann DN, et al. Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Journal of Neuromuscular Diseases. PMID 30958311 DOI: 10.3233/Jnd-190377  0.313
2019 Svaren J, Moran JJ, Wu X, Zuccarino R, Bacon C, Bai Y, Ramesh R, Gutmann L, Anderson DM, Pavelec D, Shy ME. Schwann Cell Transcript Biomarkers for Hereditary Neuropathy Skin Biopsies. Annals of Neurology. PMID 30945774 DOI: 10.1002/Ana.25480  0.39
2019 Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Schwab MH, Nave K, et al. Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy. Human Molecular Genetics. PMID 30668730 DOI: 10.1093/hmg/ddz021  0.351
2018 Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Markus Schwab H, Nave K, et al. Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy. Human Molecular Genetics. PMID 30535360 DOI: 10.1093/Hmg/Ddy420  0.533
2018 Ma KH, Duong P, Moran JJ, Junaidi N, Svaren J. Polycomb repression regulates Schwann cell proliferation and axon regeneration after nerve injury. Glia. PMID 30306639 DOI: 10.1002/Glia.23500  0.543
2018 Pantera H, Moran JJ, Hung HA, Pak E, Dutra A, Svaren J. Regulation of the neuropathy-associated Pmp22 gene by a distal super-enhancer. Human Molecular Genetics. PMID 29771329 DOI: 10.1093/Hmg/Ddy191  0.857
2018 Bai Y, Wu X, Brennan KM, Wang DS, D'Antonio M, Moran J, Svaren J, Shy ME. Myelin protein zero mutations and the unfolded protein response in Charcot Marie Tooth disease type 1B. Annals of Clinical and Translational Neurology. 5: 445-455. PMID 29687021 DOI: 10.1002/Acn3.543  0.316
2018 Dranchak P, Moran JJ, MacArthur R, Lopez-Anido C, Inglese J, Svaren J. Genome-Edited Cell Lines for High-Throughput Screening. Methods in Molecular Biology (Clifton, N.J.). 1755: 1-17. PMID 29671259 DOI: 10.1007/978-1-4939-7724-6_1  0.408
2018 Lin HP, Oksuz I, Svaren J, Awatramani R. Egr2-dependent microRNA-138 is dispensable for peripheral nerve myelination. Scientific Reports. 8: 3817. PMID 29491350 DOI: 10.1038/S41598-018-22010-8  0.393
2018 Muhammad AKMG, Kim K, Epifantseva I, Aghamaleky-Sarvestany A, Simpkinson ME, Carmona S, Landeros J, Bell S, Svaren J, Baloh RH. Cell transplantation strategies for acquired and inherited disorders of peripheral myelin. Annals of Clinical and Translational Neurology. 5: 186-200. PMID 29468179 DOI: 10.1002/Acn3.517  0.389
2018 Ma KH, Svaren J. Epigenetic Control of Schwann Cells. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 1073858417751112. PMID 29307265 DOI: 10.1177/1073858417751112  0.528
2017 Zhao HT, Damle S, Ikeda-Lee K, Kuntz S, Li J, Mohan A, Kim A, Hung G, Scheideler MA, Scherer SS, Svaren J, Swayze EE, Kordasiewicz HB. PMP22 antisense oligonucleotides reverse Charcot-Marie-Tooth disease type 1A features in rodent models. The Journal of Clinical Investigation. PMID 29202483 DOI: 10.1172/Jci96499  0.406
2017 Duncan ID, Bugiani M, Radcliff AB, Moran JJ, Lopez-Anido C, Duong P, August BK, Wolf NI, van der Knaap MS, Svaren J. A mutation in the Tubb4a gene leads to microtubule accumulation with hypomyelination and demyelination. Annals of Neurology. PMID 28393430 DOI: 10.1002/Ana.24930  0.357
2016 Ma KH, Svaren J. Epigenomic reprogramming in peripheral nerve injury. Neural Regeneration Research. 11: 1930-1931. PMID 28197188 DOI: 10.4103/1673-5374.197133  0.36
2016 Rodríguez-Molina JF, Lopez-Anido C, Ma KH, Zhang C, Olson T, Muth KN, Weider M, Svaren J. Dual specificity phosphatase 15 regulates Erk activation in Schwann cells. Journal of Neurochemistry. PMID 27891578 DOI: 10.1111/Jnc.13911  0.609
2016 Gopinath C, Law WD, Rodríguez-Molina JF, Prasad AB, Song L, Crawford GE, Mullikin JC, Svaren J, Antonellis A. Stringent comparative sequence analysis reveals SOX10 as a putative inhibitor of glial cell differentiation. Bmc Genomics. 17: 887. PMID 27821050 DOI: 10.1186/S12864-016-3167-3  0.598
2016 Ma KH, Hung HA, Svaren J. Epigenomic Regulation of Schwann Cell Reprogramming in Peripheral Nerve Injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 9135-47. PMID 27581455 DOI: 10.1523/Jneurosci.1370-16.2016  0.814
2016 Fogarty EA, Brewer MH, Rodriguez-Molina JF, Law WD, Ma KH, Steinberg NM, Svaren J, Antonellis A. SOX10 Regulates an Alternative Promoter at the Charcot-Marie-Tooth Disease Locus MTMR2. Human Molecular Genetics. PMID 27466180 DOI: 10.1093/Hmg/Ddw233  0.575
2016 Lopez-Anido C, Poitelon Y, Gopinath C, Moran JJ, Ma KH, Law WD, Antonellis A, Feltri ML, Svaren J. Tead1 regulates the expression of Peripheral Myelin Protein 22 during Schwann cell development. Human Molecular Genetics. PMID 27288457 DOI: 10.1093/Hmg/Ddw158  0.643
2016 Poitelon Y, Lopez-Anido C, Catignas K, Berti C, Palmisano M, Williamson C, Ameroso D, Abiko K, Hwang Y, Gregorieff A, Wrana JL, Asmani M, Zhao R, Sim FJ, Wrabetz L, ... Svaren J, et al. YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells. Nature Neuroscience. PMID 27273766 DOI: 10.1038/Nn.4316  0.55
2016 Damaschke NA, Yang B, Montgomery A, Svaren J, Roopra A, Luo J, Keles S, Jarrard D. Abstract 4434: CTCF acts as a master regulator to direct epigenetic events important for tumor development and progression Cancer Research. 76: 4434-4434. DOI: 10.1158/1538-7445.Am2016-4434  0.389
2015 Ma KH, Hung HA, Srinivasan R, Xie H, Orkin SH, Svaren J. Regulation of Peripheral Nerve Myelin Maintenance by Gene Repression through Polycomb Repressive Complex 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8640-52. PMID 26041929 DOI: 10.1523/Jneurosci.2257-14.2015  0.86
2015 Lopez-Anido C, Sun G, Koenning M, Srinivasan R, Hung HA, Emery B, Keles S, Svaren J. Differential Sox10 genomic occupancy in myelinating glia. Glia. PMID 25974668 DOI: 10.1002/Glia.22855  0.861
2015 Hung HA, Sun G, Keles S, Svaren J. Dynamic regulation of Schwann cell enhancers after peripheral nerve injury. The Journal of Biological Chemistry. 290: 6937-50. PMID 25614629 DOI: 10.1074/Jbc.M114.622878  0.836
2015 Romens SE, McDonald J, Svaren J, Pollak SD. Associations between early life stress and gene methylation in children. Child Development. 86: 303-9. PMID 25056599 DOI: 10.1111/Cdev.12270  0.34
2015 Lopez-Anido C, Sun G, Koenning M, Srinivasan R, Hung HA, Emery B, Keles S, Svaren J. Differential Sox10 genomic occupancy in myelinating glia Glia. DOI: 10.1002/glia.22855  0.795
2014 Sun G, Srinivasan R, Lopez-Anido C, Hung HA, Svaren J, Kele? S. In silico pooling of ChIP-seq control experiments. Plos One. 9: e109691. PMID 25380244 DOI: 10.1371/Journal.Pone.0109691  0.762
2014 Inglese J, Dranchak P, Moran JJ, Jang SW, Srinivasan R, Santiago Y, Zhang L, Guha R, Martinez N, MacArthur R, Cost GJ, Svaren J. Genome editing-enabled HTS assays expand drug target pathways for Charcot-Marie-tooth disease. Acs Chemical Biology. 9: 2594-602. PMID 25188731 DOI: 10.1021/Cb5005492  0.782
2014 Svaren J. MicroRNA and transcriptional crosstalk in myelinating glia. Neurochemistry International. 77: 50-57. PMID 24979526 DOI: 10.1016/J.Neuint.2014.06.010  0.589
2014 Brewer MH, Ma KH, Beecham GW, Gopinath C, Baas F, Choi BO, Reilly MM, Shy ME, Züchner S, Svaren J, Antonellis A. Haplotype-specific modulation of a SOX10/CREB response element at the Charcot-Marie-Tooth disease type 4C locus SH3TC2. Human Molecular Genetics. 23: 5171-87. PMID 24833716 DOI: 10.1093/Hmg/Ddu240  0.553
2014 Yang B, Wagner J, Damaschke N, Yao T, Wuerzberger-Davis SM, Lee MH, Svaren J, Miyamoto S, Jarrard DF. A novel pathway links oxidative stress to loss of insulin growth factor-2 (IGF2) imprinting through NF-κB activation. Plos One. 9: e88052. PMID 24558376 DOI: 10.1371/Journal.Pone.0088052  0.403
2014 Kim EH, Gasper DJ, Lee SH, Plisch EH, Svaren J, Suresh M. Bach2 regulates homeostasis of Foxp3+ regulatory T cells and protects against fatal lung disease in mice. Journal of Immunology (Baltimore, Md. : 1950). 192: 985-95. PMID 24367030 DOI: 10.4049/Jimmunol.1302378  0.346
2014 Pemberton TJ, Choi S, Mayer JA, Li FY, Gokey N, Svaren J, Safra N, Bannasch DL, Sullivan K, Breuhaus B, Patel PI, Duncan ID. A mutation in the canine gene encoding folliculin-interacting protein 2 (FNIP2) associated with a unique disruption in spinal cord myelination. Glia. 62: 39-51. PMID 24272703 DOI: 10.1002/Glia.22582  0.82
2013 Bujalka H, Koenning M, Jackson S, Perreau VM, Pope B, Hay CM, Mitew S, Hill AF, Lu QR, Wegner M, Srinivasan R, Svaren J, Willingham M, Barres BA, Emery B. MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes. Plos Biology. 11: e1001625. PMID 23966833 DOI: 10.1371/Journal.Pbio.1001625  0.598
2012 Oliver SS, Musselman CA, Srinivasan R, Svaren JP, Kutateladze TG, Denu JM. Multivalent recognition of histone tails by the PHD fingers of CHD5. Biochemistry. 51: 6534-44. PMID 22834704 DOI: 10.1021/Bi3006972  0.348
2012 Jang SW, Lopez-Anido C, MacArthur R, Svaren J, Inglese J. Identification of drug modulators targeting gene-dosage disease CMT1A Acs Chemical Biology. 7: 1205-1213. PMID 22530759 DOI: 10.1021/Cb300048D  0.805
2012 Srinivasan R, Sun G, Keles S, Jones EA, Jang SW, Krueger C, Moran JJ, Svaren J. Genome-wide analysis of EGR2/SOX10 binding in myelinating peripheral nerve. Nucleic Acids Research. 40: 6449-60. PMID 22492709 DOI: 10.1093/Nar/Gks313  0.845
2012 Hung H, Kohnken R, Svaren J. The Nucleosome Remodeling and Deacetylase Chromatin Remodeling (NuRD) Complex Is Required for Peripheral Nerve Myelination The Journal of Neuroscience. 32: 1517-1527. PMID 22302795 DOI: 10.1523/Jneurosci.2895-11.2012  0.856
2012 Jones EA, Brewer MH, Srinivasan R, Krueger C, Sun G, Charney KN, Keles S, Antonellis A, Svaren J. Distal enhancers upstream of the Charcot-Marie-Tooth type 1A disease gene PMP22. Human Molecular Genetics. 21: 1581-91. PMID 22180461 DOI: 10.1093/Hmg/Ddr595  0.597
2012 Gokey NG, Srinivasan R, Lopez-Anido C, Krueger C, Svaren J. Developmental regulation of microRNA expression in Schwann cells. Molecular and Cellular Biology. 32: 558-68. PMID 22064487 DOI: 10.1128/Mcb.06270-11  0.8
2012 Hodonsky CJ, Kleinbrink EL, Charney KN, Prasad M, Bessling SL, Jones EA, Srinivasan R, Svaren J, McCallion AS, Antonellis A. SOX10 regulates expression of the SH3-domain kinase binding protein 1 (Sh3kbp1) locus in Schwann cells via an alternative promoter. Molecular and Cellular Neurosciences. 49: 85-96. PMID 22037207 DOI: 10.1016/J.Mcn.2011.10.004  0.573
2011 Gokey NG, Lopez-Anido C, Gillian-Daniel AL, Svaren J. Early growth response 1 (Egr1) regulates cholesterol biosynthetic gene expression. The Journal of Biological Chemistry. 286: 29501-10. PMID 21712389 DOI: 10.1074/Jbc.M111.263509  0.793
2011 Prasad MK, Reed X, Gorkin DU, Cronin JC, McAdow AR, Chain K, Hodonsky CJ, Jones EA, Svaren J, Antonellis A, Johnson SL, Loftus SK, Pavan WJ, McCallion AS. SOX10 directly modulates ERBB3 transcription via an intronic neural crest enhancer. Bmc Developmental Biology. 11: 40. PMID 21672228 DOI: 10.1186/1471-213X-11-40  0.462
2011 Jagalur NB, Ghazvini M, Mandemakers W, Driegen S, Maas A, Jones EA, Jaegle M, Grosveld F, Svaren J, Meijer D. Functional dissection of the Oct6 Schwann cell enhancer reveals an essential role for dimeric Sox10 binding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8585-94. PMID 21653862 DOI: 10.1523/Jneurosci.0659-11.2011  0.596
2011 Chen Y, Wang H, Yoon SO, Xu X, Hottiger MO, Svaren J, Nave KA, Kim HA, Olson EN, Lu QR. HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination. Nature Neuroscience. 14: 437-41. PMID 21423191 DOI: 10.1038/Nn.2780  0.529
2011 Jones EA, Lopez-Anido C, Srinivasan R, Krueger C, Chang LW, Nagarajan R, Svaren J. Regulation of the PMP22 gene through an intronic enhancer. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4242-50. PMID 21411665 DOI: 10.1523/Jneurosci.5893-10.2011  0.623
2010 He Y, Kim JY, Dupree J, Tewari A, Melendez-Vasquez C, Svaren J, Casaccia P. Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination. Nature Neuroscience. 13: 1472-80. PMID 21057508 DOI: 10.1038/Nn.2686  0.58
2010 Jang SW, Srinivasan R, Jones EA, Sun G, Keles S, Krueger C, Chang LW, Nagarajan R, Svaren J. Locus-wide identification of Egr2/Krox20 regulatory targets in myelin genes. Journal of Neurochemistry. 115: 1409-20. PMID 21044070 DOI: 10.1111/J.1471-4159.2010.07045.X  0.858
2009 Jang SW, Svaren J. Induction of myelin protein zero by early growth response 2 through upstream and intragenic elements. The Journal of Biological Chemistry. 284: 20111-20. PMID 19487693 DOI: 10.1074/Jbc.M109.022426  0.847
2008 Svaren J, Meijer D. The molecular machinery of myelin gene transcription in Schwann cells Glia. 56: 1541-1551. PMID 18803322 DOI: 10.1002/Glia.20767  0.575
2008 Fu VX, Dobosy JR, Desotelle JA, Almassi N, Ewald JA, Srinivasan R, Berres M, Svaren J, Weindruch R, Jarrard DF. Aging and cancer-related loss of insulin-like growth factor 2 imprinting in the mouse and human prostate. Cancer Research. 68: 6797-802. PMID 18701505 DOI: 10.1158/0008-5472.Can-08-1714  0.323
2008 Dobosy JR, Fu VX, Desotelle JA, Srinivasan R, Kenowski ML, Almassi N, Weindruch R, Svaren J, Jarrard DF. A methyl-deficient diet modifies histone methylation and alters Igf2 and H19 repression in the prostate. The Prostate. 68: 1187-95. PMID 18459101 DOI: 10.1002/Pros.20782  0.307
2008 Mager GM, Ward RM, Srinivasan R, Jang SW, Wrabetz L, Svaren J. Active gene repression by the Egr2.NAB complex during peripheral nerve myelination. The Journal of Biological Chemistry. 283: 18187-97. PMID 18456662 DOI: 10.1074/Jbc.M803330200  0.842
2008 Tureyen K, Brooks N, Bowen K, Svaren J, Vemuganti R. Transcription factor early growth response-1 induction mediates inflammatory gene expression and brain damage following transient focal ischemia. Journal of Neurochemistry. 105: 1313-24. PMID 18208539 DOI: 10.1111/J.1471-4159.2008.05233.X  0.329
2007 Jones EA, Jang SW, Mager GM, Chang LW, Srinivasan R, Gokey NG, Ward RM, Nagarajan R, Svaren J. Interactions of Sox10 and Egr2 in myelin gene regulation. Neuron Glia Biology. 3: 377-87. PMID 18634568 DOI: 10.1017/S1740925X08000173  0.806
2007 Srinivasan R, Jang SW, Ward RM, Sachdev S, Ezashi T, Svaren J. Differential regulation of NAB corepressor genes in Schwann cells. Bmc Molecular Biology. 8: 117. PMID 18096076 DOI: 10.1186/1471-2199-8-117  0.827
2007 Shamim M, Nanjappa SG, Singh A, Plisch EH, LeBlanc SE, Walent J, Svaren J, Seroogy C, Suresh M. Cbl-b regulates antigen-induced TCR down-regulation and IFN-gamma production by effector CD8 T cells without affecting functional avidity. Journal of Immunology (Baltimore, Md. : 1950). 179: 7233-43. PMID 18025165 DOI: 10.4049/Jimmunol.179.11.7233  0.744
2007 Muir P, Schaefer SL, Manley PA, Svaren JP, Oldenhoff WE, Hao Z. Expression of immune response genes in the stifle joint of dogs with oligoarthritis and degenerative cranial cruciate ligament rupture Veterinary Immunology and Immunopathology. 119: 214-221. PMID 17629954 DOI: 10.1016/J.Vetimm.2007.05.016  0.309
2007 LeBlanc SE, Ward RM, Svaren J. Neuropathy-associated Egr2 mutants disrupt cooperative activation of myelin protein zero by Egr2 and Sox10. Molecular and Cellular Biology. 27: 3521-9. PMID 17325040 DOI: 10.1128/Mcb.01689-06  0.839
2006 Jang SW, LeBlanc SE, Roopra A, Wrabetz L, Svaren J. In vivo detection of Egr2 binding to target genes during peripheral nerve myelination. Journal of Neurochemistry. 98: 1678-87. PMID 16923174 DOI: 10.1111/J.1471-4159.2006.04069.X  0.855
2006 Srinivasan R, Mager GM, Ward RM, Mayer J, Svaren J. NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex. The Journal of Biological Chemistry. 281: 15129-37. PMID 16574654 DOI: 10.1074/Jbc.M600775200  0.814
2006 LeBlanc SE, Jang SW, Ward RM, Wrabetz L, Svaren J. Direct regulation of myelin protein zero expression by the Egr2 transactivator. The Journal of Biological Chemistry. 281: 5453-60. PMID 16373334 DOI: 10.1074/Jbc.M512159200  0.855
2005 Le N, Nagarajan R, Wang JY, Svaren J, LaPash C, Araki T, Schmidt RE, Milbrandt J. Nab proteins are essential for peripheral nervous system myelination. Nature Neuroscience. 8: 932-40. PMID 16136673 DOI: 10.1038/Nn1490  0.578
2005 Leblanc SE, Srinivasan R, Ferri C, Mager GM, Gillian-Daniel AL, Wrabetz L, Svaren J. Regulation of cholesterol/lipid biosynthetic genes by Egr2/Krox20 during peripheral nerve myelination. Journal of Neurochemistry. 93: 737-48. PMID 15836632 DOI: 10.1111/J.1471-4159.2005.03056.X  0.823
2005 Fu VX, Kenowski ML, Schwarze SR, LeBlanc S, Svaren J, Jarrard DF. 252: A Loss of Insulin-Like Growth Factor-2 (IGF2) Imprinting is Modulated by CTCF Downregulation at Senescence in Human Epithelial Cells Journal of Urology. 173: 69-69. DOI: 10.1016/S0022-5347(18)34517-8  0.744
2004 Fu VX, Schwarze SR, Kenowski ML, Leblanc S, Svaren J, Jarrard DF. A loss of insulin-like growth factor-2 imprinting is modulated by CCCTC-binding factor down-regulation at senescence in human epithelial cells. The Journal of Biological Chemistry. 279: 52218-26. PMID 15471867 DOI: 10.1074/Jbc.M405015200  0.787
2004 Pal S, Nemeth MJ, Bodine D, Miller JL, Svaren J, Thein SL, Lowry PJ, Bresnick EH. Neurokinin-B transcription in erythroid cells: direct activation by the hematopoietic transcription factor GATA-1. The Journal of Biological Chemistry. 279: 31348-56. PMID 15123623 DOI: 10.1074/Jbc.M403475200  0.36
2004 Gillian AL, Svaren J. The Ddx20/DP103 Dead Box Protein Represses Transcriptional Activation by Egr2/Krox-20 Journal of Biological Chemistry. 279: 9056-9063. PMID 14699164 DOI: 10.1074/Jbc.M309308200  0.546
2002 Venken K, Di Maria E, Bellone E, Balestra P, Cassandrini D, Mandich P, De Jonghe P, Timmerman V, Svaren J. Search for mutations in the EGR2 corepressor proteins, NAB1 and NAB2, in human peripheral neuropathies. Neurogenetics. 4: 37-41. PMID 12030330 DOI: 10.1007/S10048-001-0124-2  0.385
2001 Nagarajan R, Svaren J, Le N, Araki T, Watson M, Milbrandt J. EGR2 mutations in inherited neuropathies dominant-negatively inhibit myelin gene expression. Neuron. 30: 355-68. PMID 11394999 DOI: 10.1016/S0896-6273(01)00282-3  0.595
2001 Houston P, Campbell CJ, Svaren J, Milbrandt J, Braddock M. The transcriptional corepressor NAB2 blocks Egr-1-mediated growth factor activation and angiogenesis. Biochemical and Biophysical Research Communications. 283: 480-6. PMID 11327726 DOI: 10.1006/Bbrc.2001.4810  0.388
2000 Svaren J, Ehrig T, Abdulkadir SA, Ehrengruber MU, Watson MA, Milbrandt J. EGR1 Target Genes in Prostate Carcinoma Cells Identified by Microarray Analysis Journal of Biological Chemistry. 275: 38524-38531. PMID 10984481 DOI: 10.1074/Jbc.M005220200  0.427
2000 Sevetson BR, Svaren J, Milbrandt J. A Novel Activation Function for NAB Proteins in EGR-dependent Transcription of the Luteinizing Hormone β Gene Journal of Biological Chemistry. 275: 9749-9757. PMID 10734128 DOI: 10.1074/Jbc.275.13.9749  0.478
2000 Bergh FT, Flinn EM, Svaren J, Wright AP, Hörz W. Comparison of nucleosome remodeling by the yeast transcription factor Pho4 and the glucocorticoid receptor Journal of Biological Chemistry. 275: 9035-9042. PMID 10722753 DOI: 10.1074/Jbc.275.12.9035  0.404
1999 Warner LE, Svaren J, Milbrandt J, Lupski JR. Functional Consequences of Mutations in the Early Growth Response 2 Gene (EGR2) Correlate with Severity of Human Myelinopathies Human Molecular Genetics. 8: 1245-1251. PMID 10369870 DOI: 10.1093/Hmg/8.7.1245  0.433
1999 Dorn C, Ou Q, Svaren J, Crawford PA, Sadovsky Y. Activation of luteinizing hormone beta gene by gonadotropin-releasing hormone requires the synergy of early growth response-1 and steroidogenic factor-1. The Journal of Biological Chemistry. 274: 13870-6. PMID 10318795 DOI: 10.1074/Jbc.274.20.13870  0.401
1998 Svaren J, Sevetson BR, Golda T, Stanton JJ, Swirnoff AH, Milbrandt J. Novel mutants of NAB corepressors enhance activation by Egr transactivators The Embo Journal. 17: 6010-6019. PMID 9774344 DOI: 10.1093/Emboj/17.20.6010  0.414
1998 McAndrew PC, Svaren J, Martin SR, Hörz W, Goding CR. Requirements for Chromatin Modulation and Transcription Activation by the Pho4 Acidic Activation Domain Molecular and Cellular Biology. 18: 5818-5827. PMID 9742099 DOI: 10.1128/Mcb.18.10.5818  0.38
1998 Qu Z, Wolfraim LA, Svaren J, Ehrengruber MU, Davidson N, Milbrandt J. The transcriptional corepressor NAB2 inhibits NGF-induced differentiation of PC12 cells Journal of Cell Biology. 142: 1075-1082. PMID 9722618 DOI: 10.1083/Jcb.142.4.1075  0.374
1998 Swirnoff AH, Apel ED, Svaren J, Sevetson BR, Zimonjic DB, Popescu NC, Milbrandt J. Nab1, a Corepressor of NGFI-A (Egr-1), Contains an Active Transcriptional Repression Domain Molecular and Cellular Biology. 18: 512-524. PMID 9418898 DOI: 10.1128/Mcb.18.1.512  0.512
1997 Svaren J, Apel ED, Simburger KS, Jenkins NA, Gilbert DJ, Copeland NA, Milbrandt J. The Nab2 and Stat6 genes share a common transcription termination region. Genomics. 41: 33-9. PMID 9126479 DOI: 10.1006/Geno.1997.4609  0.451
1997 Svaren J, Hörz W. Transcription factors vs nucleosomes: regulation of the PH05 promoter in yeast Trends in Biochemical Sciences. 22: 93-97. PMID 9066259 DOI: 10.1016/S0968-0004(97)01001-3  0.384
1996 Barbaric S, Münsterkötter M, Svaren J, Hörz W. The Homeodomain Protein Pho2 and the Basic-Helix-Loop-Helix Protein Pho4 Bind DNA Cooperatively at the Yeast PHO5 Promoter Nucleic Acids Research. 24: 4479-4486. PMID 8948638 DOI: 10.1093/Nar/24.22.4479  0.384
1996 Svaren J, Hörz W. Regulation of gene expression by nucleosomes. Current Opinion in Genetics & Development. 6: 164-170. PMID 8722172 DOI: 10.1016/S0959-437X(96)80046-3  0.44
1996 Svaren J, Sevetson BR, Apel ED, Zimonjic DB, Popescu NC, Milbrandt J. NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli. Molecular and Cellular Biology. 16: 3545-3553. PMID 8668170 DOI: 10.1128/Mcb.16.7.3545  0.495
1995 Svaren J, Hörz W. Interplay between nucleosomes and transcription factors at the yeastPHO5promoter Seminars in Cell Biology. 6: 177-183. PMID 8562909 DOI: 10.1006/Scel.1995.0025  0.401
1994 Svaren J, Schmitz J, Hörz W. The transactivation domain of Pho4 is required for nucleosome disruption at the PHO5 promoter. The Embo Journal. 13: 4856-4862. DOI: 10.1002/J.1460-2075.1994.Tb06812.X  0.39
1994 Venter U, Svaren J, Schmitz J, Schmid A, Hörz W. A nucleosome precludes binding of the transcription factor Pho4 in vivo to a critical target site in the PHO5 promoter. The Embo Journal. 13: 4848-4855. DOI: 10.1002/J.1460-2075.1994.Tb06811.X  0.409
1993 Svaren J, Hörz W. Histones, nucleosomes and transcription. Current Opinion in Genetics & Development. 3: 219-225. PMID 8389216 DOI: 10.1016/0959-437X(93)90026-L  0.426
1990 Svaren J, Chalkley R. The structure and assembly of active chromatin. Trends in Genetics : Tig. 6: 52-6. PMID 2186529 DOI: 10.1016/0168-9525(90)90074-G  0.364
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