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Scott Snapper - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Crohn's disease, veoIBD
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45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Vardi I, Chermesh I, Werner L, Barel O, Freund T, McCourt C, Fisher Y, Pinsker M, Javasky E, Weiss B, Rechavi G, Hagin D, Snapper SB, Somech R, Konnikova L, et al. Monogenic Inflammatory Bowel Disease: It's Never Too Late to Make a Diagnosis. Frontiers in Immunology. 11: 1775. PMID 33013830 DOI: 10.3389/Fimmu.2020.01775  0.303
2019 Magg T, Shcherbina A, Arslan D, Desai MM, Wall S, Mitsialis V, Conca R, Unal E, Karacabey N, Mukhina A, Rodina Y, Taur PD, Illig D, Marquardt B, Hollizeck S, ... ... Snapper SB, et al. CARMIL2 Deficiency Presenting as Very Early Onset Inflammatory Bowel Disease. Inflammatory Bowel Diseases. PMID 31115454 DOI: 10.1093/Ibd/Izz103  0.333
2019 Tsou A, Goettel J, Biswas A, Kang YH, Saltzman J, Kelly R, Gringauz J, Shen Z, Fox J, Horwitz B, Snapper S. P155 Elucidating Interactions Between The Immune System And The Gut Microbiota In A Reductionist Murine Model Of Inflammatory Bowel Disease Gastroenterology. 156. DOI: 10.1053/J.Gastro.2019.01.241  0.31
2018 Li Y, Führer M, Bahrami E, Socha P, Klaudel-Dreszler M, Bouzidi A, Liu Y, Lehle AS, Magg T, Hollizeck S, Rohlfs M, Conca R, Field M, Warner N, Mordechai S, ... ... Snapper SB, et al. Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases. Proceedings of the National Academy of Sciences of the United States of America. PMID 30591564 DOI: 10.1073/pnas.1813582116  0.327
2018 Haberman Y, Schirmer M, Dexheimer PJ, Karns R, Braun T, Kim MO, Walters TD, Baldassano RN, Noe JD, Rosh J, Markowitz J, Crandall WV, Mack DR, Griffiths AM, Heyman MB, ... ... Snapper S, et al. Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis. Mucosal Immunology. PMID 30542108 DOI: 10.1038/S41385-018-0114-4  0.338
2018 Lehle AS, Farin HF, Marquardt B, Michels BE, Magg T, Li Y, Liu Y, Ghalandary M, Lammens K, Hollizeck S, Rohlfs M, Hauck F, Conca R, Walz C, Weiss B, ... ... Snapper SS, et al. Intestinal Inflammation and Dysregulated Immunity in Patients with Inherited Caspase-8 Deficiency. Gastroenterology. PMID 30267714 DOI: 10.1053/J.Gastro.2018.09.041  0.313
2018 Egg D, Schwab C, Gabrysch A, Arkwright PD, Cheesman E, Giulino-Roth L, Neth O, Snapper S, Okada S, Moutschen M, Delvenne P, Pecher AC, Wolff D, Kim YJ, Seneviratne S, et al. Increased Risk for Malignancies in 131 Affected Mutation Carriers. Frontiers in Immunology. 9: 2012. PMID 30250467 DOI: 10.3389/Fimmu.2018.02012  0.332
2018 Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Alexander Valencia C, Dodd A, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, ... ... Snapper S, et al. Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease. Inflammatory Bowel Diseases. PMID 30124884 DOI: 10.1093/Ibd/Izy265  0.309
2018 Chandradevan R, Hofmekler T, Mondal K, Harun N, Venkateswaran S, Somineni HK, Ballengee CR, Kim MO, Griffiths A, Noe JD, Crandall WV, Snapper S, Rabizadeh S, Rosh JR, Walters TD, et al. Evolution of Pediatric Inflammatory Bowel Disease Unclassified (IBD-U): Incorporated With Serological and Gene Expression Profiles. Inflammatory Bowel Diseases. PMID 29860529 DOI: 10.1093/Ibd/Izy136  0.31
2018 Schwab C, Gabrysch A, Olbrich P, Patiño V, Warnatz K, Wolff D, Hoshino A, Kobayashi M, Imai K, Takagi M, Dybedal I, Haddock JA, Sansom D, Lucena JM, Seidl M, ... ... Snapper S, et al. Phenotype, penetrance, and treatment of 133 CTLA-4-insufficient individuals. The Journal of Allergy and Clinical Immunology. PMID 29729943 DOI: 10.1016/J.Jaci.2018.02.055  0.345
2018 Shaw KA, Cutler DJ, Okou D, Dodd A, Aronow BJ, Haberman Y, Stevens C, Walters TD, Griffiths A, Baldassano RN, Noe JD, Hyams JS, Crandall WV, Kirschner BS, Heyman MB, ... Snapper S, et al. Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort. Genes and Immunity. PMID 29593342 DOI: 10.1038/S41435-018-0015-2  0.327
2018 Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Dodd A, Quinn K, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, ... ... Snapper S, et al. Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients with Crohn's Disease. Gastroenterology. PMID 29454792 DOI: 10.1053/J.Gastro.2018.02.016  0.319
2018 McCabe A, Brendel C, Frei S, Klatt D, Bentler M, Snapper S, Williams DA. Interleukin-10 Signaling in Hematopoietic Stem and Progenitor Cells Maintains Stem Cell Function and Regulates Inflammation-Induced Myeloid Cell Output Blood. 132: 2407-2407. DOI: 10.1182/Blood-2018-99-116168  0.374
2018 Farachi S, Werner L, Konnikova L, Rea F, Vardi I, Romeo E, Barel O, De Angelis P, Dall’Oglio L, Rechavi G, Snapper S, Somech R, Weiss B, Cancrini C, Shouval D. DOP010 Activating PIK3CD mutations cause severe intestinal lymphonodular hyperplasia and an IBD-like phenotype Journal of Crohn's and Colitis. 12: S036-S037. DOI: 10.1093/Ecco-Jcc/Jjx180.047  0.348
2017 Li J, Shouval D, Doty A, Snapper S, Glover S. P356 Treatment with anakinra induces T cell production of IL22 and GI mucosal healing in an IL-10RA mutation patient Journal of Crohn's and Colitis. 11: S258-S258. DOI: 10.1093/Ecco-Jcc/Jjx002.481  0.307
2016 Koroleva E, Muraoka W, Spencer C, Gubernatorova E, Halperin S, Snapper S, Tumanov A. O-009 Lymphotoxin Links Microbiota and Group 3 Innate Lymphoid Cells to Protect Against Intestinal Inflammation. Inflammatory Bowel Diseases. 22: S3-4. PMID 26849727 DOI: 10.1097/01.Mib.0000480047.19127.68  0.367
2016 Biswas A, Shouval D, Goettel J, Field M, Griffith A, Pai SY, Notarangelo L, Geha R, Snapper S. O-008 Aberrant Anti-inflammatory Macrophage Function and Differentiation in Wiskott-Aldrich Syndrome Protein-Deficient Mice and Humans. Inflammatory Bowel Diseases. 22: S3. PMID 26849726 DOI: 10.1097/01.Mib.0000480046.11503.1E  0.302
2016 Redhu N, Shouval D, Bakthavatchalu V, Wang C, Conaway E, Goettel J, Mack M, Bleich A, Bry L, Fox J, Snapper S, Horwitz B. O-005 YI Microbiota Drives Inflammation by Altering Intestinal Lamina Propria Macrophage Phenotype in a Novel IL10R-Deficient Model of Very Early Onset IBD. Inflammatory Bowel Diseases. 22: S2-S3. PMID 26849723 DOI: 10.1097/01.Mib.0000480043.65761.B2  0.311
2016 Sugimura R, Han A, Jha D, Lu Y, Goettel JA, Serrao E, Rowe RG, Wong I, Sousa P, Ditadi A, Keller G, Engelman A, Snapper S, Doulatov S, Daley GQ. Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells Via Transcription Factor Conversion of Hemogenic Endothelium Blood. 128: 371-371. DOI: 10.1182/Blood.V128.22.371.371  0.371
2016 Otsubo T, Alsahwi N, Wahed R, Anand R, Cheifetz AS, Wolf JL, Bousvaros A, Snapper S, Lamont JT, Robson S, Moss AC, Kokkotou E. P-108 Infliximab-Associated Suppression of Cytokine Release by Mucosal Explants Predicts Success of Anti-TNF Therapy in Patients with Inflammatory Bowel Disease Inflammatory Bowel Diseases. 22. DOI: 10.1097/01.Mib.0000480213.77049.Cc  0.301
2015 Volpi S, Santori E, Abernethy K, Mizui M, Dahlberg CI, Recher M, Capuder K, Csizmadia E, Ryan D, Mathew D, Tsokos GC, Snapper S, Westerberg LS, Thrasher AJ, Candotti F, et al. N-WASP is required for B cell-mediated autoimmunity in the Wiskott-Aldrich syndrome. Blood. PMID 26468226 DOI: 10.1182/Blood-2015-05-643817  0.383
2015 Dahlberg CI, Torres ML, Petersen SH, Baptista MA, Keszei M, Volpi S, Grasset EK, Karlsson MC, Walter JE, Snapper SB, Notarangelo LD, Westerberg LS. Deletion of WASp and N-WASp in B cells cripples the germinal center response and results in production of IgM autoantibodies. Journal of Autoimmunity. PMID 26143192 DOI: 10.1016/J.Jaut.2015.06.003  0.304
2013 Schell C, Baumhakl L, Salou S, Conzelmann AC, Meyer C, Helmstädter M, Wrede C, Grahammer F, Eimer S, Kerjaschki D, Walz G, Snapper S, Huber TB. N-wasp is required for stabilization of podocyte foot processes. Journal of the American Society of Nephrology : Jasn. 24: 713-21. PMID 23471198 DOI: 10.1681/Asn.2012080844  0.323
2013 Garber J, Mallick E, Scanlon K, Donnenberg M, Leong J, Snapper S. O-029 The Attaching-and-effacing Pathogen Effector EspF Exploits Homeostatic Tight Junction Regulatory Activities of N-WASP and SNX9 to Induce Intestinal Barrier Dysfunction Inflammatory Bowel Diseases. 19: S16-S17. DOI: 10.1097/01.Mib.0000438580.80786.65  0.324
2013 Shouval D, Biswas A, Goettel J, McCann K, Conaway E, Lavoie S, Samsom J, Escher J, Somech R, Weiss B, Conklin L, Bhan A, Muise A, Horwitz B, Snapper S. O-022 YI Innate Immune IL10 Receptor Signaling Regulates Mucosal Homeostasis and the Function of Anti-inflammatory Macrophages Inflammatory Bowel Diseases. 19. DOI: 10.1097/01.Mib.0000438573.48506.67  0.314
2013 Dhillon SS, Mastropaolo LA, Thoeni CE, Elkadri AA, Xu W, Walters TD, Guo C, Mack DR, Huynh HQ, Baksh S, Silverberg MS, Fiedler K, Brumell J, Snapper S, Muise AM. Tu1943 Higher Activity of the Inducible Nitric Oxide Synthase Contributes to Very Early Onset of Inflammatory Bowel Disease Gastroenterology. 144: S-886. DOI: 10.1016/S0016-5085(13)63299-0  0.306
2013 Goettel JA, Ouahed J, McCann K, Muise AM, Snapper S. Mo1976 Development of Novel Humanized Murine Models to Assess Mucosal Homeostasis: Human T Cells From Ipex (Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked) Patients Transfer Clinical Phenotype to Immunodeficient Mice Expressing Human Class II Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)62628-1  0.306
2013 Wurbel M, Ibourk M, McIntire MG, Fiebiger E, Snapper S. Sa1794 CCL25/CCR9 Interactions Are Not Necessary for T Cell Colitogenicity but Are Required for Innate Immune Cell Protection in Murine Experimental Chronic Colitis Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)61105-1  0.368
2012 Recher M, Burns SO, de la Fuente MA, Volpi S, Dahlberg C, Walter JE, Moffitt K, Mathew D, Honke N, Lang PA, Patrizi L, Falet H, Keszei M, Mizui M, Csizmadia E, ... ... Snapper S, et al. B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice. Blood. 119: 2819-28. PMID 22302739 DOI: 10.1182/Blood-2011-09-379412  0.356
2012 Shouval D, Goettel J, Wurbel M, Horwitz B, Snapper S. IL-10 Receptor Signaling in Intestinal Innate Immune Cells is Critical for Maintaining Mucosal Homeostasis: P-237 YI Inflammatory Bowel Diseases. 18. DOI: 10.1097/00054725-201212001-00270  0.313
2012 Garber J, Mallick E, Leong J, Snapper S. Enteropathogenic E. coli Induces Intestinal Barrier Dysfunction by Exploiting Novel N-WASP-Mediated Cytoskeletal Junction Regulatory Activities Inflammatory Bowel Diseases. 18: S99. DOI: 10.1097/00054725-201212001-00250  0.318
2011 Wurbel M, McIntire M, Pardo M, Snapper S, Fiebiger E. Gradual disappearance of intestinal CD103+ dendritic cells in intestinal mucosa of CCR9−/− mice in an experimental chronic DSS-mediated colitis: P-215. Inflammatory Bowel Diseases. 17. DOI: 10.1097/00054725-201112002-00249  0.301
2011 Boden E, Goettel J, Ahmed O, Moran C, Nguyen D, Dunkin D, Mayer L, Snapper S. The Wiskott Aldrich Syndrome protein (WASp) reduces T cell proliferation and regulatory T cell induction via increased sensitivity to TGFβ: P-210. Inflammatory Bowel Diseases. 17. DOI: 10.1097/00054725-201112002-00244  0.35
2011 Boden E, Ahuja V, Moran C, Nguyen D, Mayer L, Snapper S. The Wiskott-Aldrich Syndrome protein alters Treg homeostasis via reduced strength of T cell receptor signaling. Inflammatory Bowel Diseases. 17. DOI: 10.1093/Ibd/17.Supplement1.S3C  0.325
2010 Westerberg LS, Meelu P, Baptista M, Eston MA, Adamovich DA, Cotta-de-Almeida V, Seed B, Rosen MK, Vandenberghe P, Thrasher AJ, Klein C, Alt FW, Snapper SB. Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes. The Journal of Experimental Medicine. 207: 1145-52. PMID 20513746 DOI: 10.1084/Jem.20091245  0.648
2010 Nguyen D, Eston M, Snapper S. Aberrant Innate Immune Cells can Induce Normal T Cells to Become Colitogenic Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.109  0.37
2010 Quintana F, Santiago A, Yeste A, Tukpah A, Blanco LR, Garber J, Snapper S, Mittal A, Oukka M, Weiner H. AHR Controls the Production of Mucosal IL-22 by CD4+ T Cells and NK Cells Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.090  0.318
2009 Adamovich DA, Nakamura F, Worth A, Burns S, Thrasher AJ, Hartwig JH, Snapper SB. Activating mutations of N-WASP alter Shigella pathogenesis. Biochemical and Biophysical Research Communications. 384: 284-9. PMID 19379711 DOI: 10.1016/J.Bbrc.2009.04.050  0.635
2009 Boztug K, Kotlarz D, Glocker E, Gertz ME, Schäffer AA, Noyan F, Perro M, Diestelhorst J, Allroth A, Murugan D, Hätscher N, Pfeifer D, Sykora K, Sauer M, Kreipe H, ... ... Snapper S, et al. Severe Early-Onset Inflammatory Bowel Disease Caused by IL10 Receptor Deficiency Can Be Cured by Allogeneic Hematopoietic Stem Cell Transplantation. Blood. 114: 713-713. DOI: 10.1182/Blood.V114.22.713.713  0.331
2009 Glocker E, Kotlarz D, Boztug K, Gertz E, Schaffer A, Koletzko S, Shah N, Segal A, Snapper S, Grimbacher B, Klein C. Early-onset inflammatory bowel disease caused by loss-of-function mutations in the IL10-receptor genes: P-0168. Inflammatory Bowel Diseases. 15. DOI: 10.1097/00054725-200912002-00177  0.331
2008 Maillard M, Nguyen D, Boden E, Snapper S. Regulatory T cell-based cellular therapy prevents colitis in WASP-deficient mice: O-021. Inflammatory Bowel Diseases. 14. DOI: 10.1097/00054725-200801001-00021  0.302
2005 Papayannopoulos V, Co C, Prehoda KE, Snapper S, Taunton J, Lim WA. A polybasic motif allows N-WASP to act as a sensor of PIP(2) density. Molecular Cell. 17: 181-91. PMID 15664188 DOI: 10.1016/J.Molcel.2004.11.054  0.32
2002 Krawczyk C, Oliveira-dos-Santos A, Sasaki T, Griffiths E, Ohashi PS, Snapper S, Alt F, Penninger JM. Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells. Immunity. 16: 331-43. PMID 11911819 DOI: 10.1016/S1074-7613(02)00291-1  0.345
2001 Dao T, Exley M, Mehal WZ, Tahir SMA, Snapper S, Taniguchi M, Balk SP, Crispe IN. Involvement of CD1 in Peripheral Deletion of T Lymphocytes Is Independent of NK T Cells Journal of Immunology. 166: 3090-3097. PMID 11207260 DOI: 10.4049/Jimmunol.166.5.3090  0.355
1999 Sonoda KH, Exley M, Snapper S, Balk SP, Stein-Streilein J. Cd1-Reactive Natural Killer T Cells Are Required for Development of Systemic Tolerance through an Immune-Privileged Site Journal of Experimental Medicine. 190: 1215-1226. PMID 10544194 DOI: 10.1084/Jem.190.9.1215  0.34
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